ФАРМАЦЕВТИЧЕСКИЕ КОМПОЗИЦИИ, ОБЛАДАЮЩИЕ ПОВЫШЕННОЙ ЭФФЕКТИВНОСТЬЮ И УЛУЧШЕННОЙ ОБРАБАТЫВАЕМОСТЬЮ

FIELD: chemistry. SUBSTANCE: invention relates to a polymer comprising hydroxypropyl methyl cellulose acetate succinate (HPMC-AS) wherein a percentage of a total degree of substitution (DS) of succinoyl in position C 6 -OH is less than or equal to 6% (C 6 C3 Suc , % ≤ 6%) and in position C 3 -OH is from 58 to 84% (58% < C 3 C3 Suc , % < 84%), and percentage of a total DS of acetyl in position C 6 -OH ranges from 33 to 51% (33% < C 6 C3 Ac , % < 51%) and in position C 3 -OH ranges from 16 to 20% (16% < C 3 C3 Ac , % < 20%). Invention relates to a composition for improving the efficiency and improving the processability of a medicament that comprises a medicament and a said polymer, as well as a process for the preparation of hydroxypropyl methyl cellulose acetate succinate (HPMC-AS) having a percentage of a total DS of succinoyl in position C 6 -OH less than or equal to 6% (C 6 C3 Suc , % ≤ 6%) and in position C 3 -OH from 58 to 84% (58% < C 3 C3 Suc , % < 84%), and a percentage of a total DS of acetyl, in position C 6 -OH of 33 to 51% (33% < C 6 C3 Ac , % < 51%) and in position C 3 -OH of 16 to 20% (16% < C 3 C3 Ac , % < 20%), comprising steps of (a) reacting acetic anhydride and sodium acetate with hydroxyl propyl methylcellulose to form an intermediate at a temperature in the range of from about 85 to about 115°C; (b) maintaining the temperature for a period of 30 minutes to 2.5 hours and (c) reacting succinic anhydride with the intermediate product at a temperature for a period of 2.5 to 23.5 hours to obtain HPMC-AS. EFFECT: increasing the effectiveness of the drug and improving processability. 10 cl, 16 dwg, 11 tbl РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 2 656 662 C2 (51) МПК C08B 13/00 (2006.01) C08L 1/32 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ОПИСАНИЕ ИЗОБРЕТЕНИЯ К ПАТЕНТУ (52) СПК A61K 31/397 (2017.08); A61K 31/4418 (2017.08); A61K 47/38 (2017.08); C08B 13/00 (2017.08); C08L 1/32 (2017.08) (21)( ...

ФИКСАТОРЫ ДЛЯ ВОЛОС, ВКЛЮЧАЮЩИЕ ПОЛИГЛЮКОЗНЫЕ ПОЛИМЕРЫ НА ОСНОВЕ ПРОСТОГО ЭФИРА ЦЕЛЛЮЛОЗЫ

ВОДОРАСТВОРИМАЯ НИЗКОЗАМЕЩЕННАЯ ГИДРОКСИЭТИЛЦЕЛЛЮЛОЗА, ЕЕ ПРОИЗВОДНЫЕ, СПОСОБ ЕЕ ПОЛУЧЕНИЯ И ПРИМЕНЕНИЕ

... 1. Композиция, включающая гидроксиэтилцеллюлозу (ГЭЦ), содержащую гидроксиэтильные группы, которые равномерно распределены в главной цепи целлюлозы, где доля незамещенных тримеров (НЗР) меньше примерно 0,21, водорастворимость превышает примерно 90%, а гидроксиэтильное молярное замещение превышает примерно 0,7 и составляет меньше примерно 1,3. ! 2. Композиция по п.1, в которой гидроксиэтилцеллюлозу далее модифицируют одним или несколькими заместителями, содержащими химическую функциональную группу, выбранную из группы, включающей неионогенные, анионогенные, катионогенные группы и их смеси. ! 3. Композиция по п.2, в которой заместители присоединяются к главной цепи гидроксиэтилцеллюлозы посредством простого эфирного, сложноэфирного или уретанового связующего остатка. ! 4. Композиция по п.2, содержащиеся в которой заместители обладают неионогенной химической функциональной группой. ! 5. Композиция по п.4, в которой заместители отвечают формуле --R или --A-R, ! где А выбирают из группы, включающей ...

Biopolymer compositions and products thereof

OPHTALMIC COMPOSITIONS

An aqueous ophthalmic solution containing 0.2 to 2.5 percent by weight a polymeric demulcent, 0.045 to 0.065 percent by weight a calcium salt, and 0.14 to 1.4 percent by weight a phosphate salt. The solution has a viscosity of 20 to 150 centipoise and is buffered to a PH 5.5 to 8.5.

[BIOPOLIMERNYE] COMPOSITIONS AND PRODUCTS ON THEIR BASIS

METHOD FOR PRODUCING HYPROMELLOSE PHTHALATE

HYDROXYPROPYL METHYL CELLULOSE ACETATE SUCCINATE WITH ENHANCED ACETATE AND SUCCINATE SUBSTITUTION

Disclosed are polymers of hydroxypropyl methyl cellulose acetate succinate (HPMCAS) with unique degrees of substitution of hydroxypropoxy, methoxy, acetyl, and succinoyl groups. When used in making compositions comprising a low- solubility active agent and such polymers, the polymers provide increased aqueous concentrations and/or improved physical stability of the active agent.

OPHTALMIC COMPOSITIONS

An aqueous ophthalmic solution containing 0.2 to 2.5 percent by weight a polymeric demulcent, 0.045 to 0.065 percent by weight a calcium salt, and 0.14 to 1.4 percent by weight a phosphate salt. The solution has a viscosity of 20 to 150 centipoise and is buffered to a PH 5.5 to 8.5.

LOW MOLECULAR WEIGHT CELLULOSE MIXED ESTERS AND THEIR USE AS LOW VISCOSITY BINDERS AND MODIFIERS IN COATING COMPOSITIONS

Cellulose mixed esters are disclosed having low molecular weights and low degrees of polymerization. These new cellulose mixed esters include cellulose acetate propionate and cellulose acetate butyrate. The esters exhibit solubility in a wide range of organic solvents with minimal viscosity increase, are compatible with a wide variety of resins, and are useful in coatings and inks compositions as binder resins and rheology modifiers.

Hair Fixatives Including Cellulose Ether Based Polyglucose Polymers

A hair fixative composition includes at least one carboxylated cellulose ether based polyglucose polymer, an alcohol based solvent system, and a cosmetically acceptable additive, wherein the polyglucose polymer is soluble in the alcohol based solvent system. The polyglucose polymer is obtained by reacting at least one cellulose ether with at least one anhydride.

BIODEGRADABLE BLENDS AND FILMS HAVING NANO-STRUCTURAL FEATURES

СПОСОБЫ И КОМПОЗИЦИИ ДЛЯ РЕГУЛИРОВАНИЯ ВЕСА И ДЛЯ УЛУЧШЕНИЯ ГЛИКЕМИЧЕСКОГО КОНТРОЛЯ

... 1. Модифицированный пищевой продукт или продукт питания, содержащий пригодный в пищу полимерный гидрогель.2. Модифицированный пищевой продукт или продукт питания по п.1, отличающийся тем, что указанный пригодный в пищу полимерный гидрогель имеет коэффициент набухания 40 или больше.3. Модифицированный пищевой продукт или продукт питания по п.1, отличающийся тем, что указанный пригодный в пищу полимерный гидрогель имеет коэффициент набухания 80 или больше.4. Модифицированный пищевой продукт или продукт питания по п.1, отличающийся тем, что указанный пригодный в пищу полимерный гидрогель имеет модуль упругости не менее 200 Па.5. Модифицированный пищевой продукт или продукт питания по п.1, отличающийся тем, что указанный пригодный в пищу полимерный гидрогель имеет вязкость не менее 15 s.6. Модифицированный пищевой продукт или продукт питания по п.1, отличающийся тем, что пищевой продукт или продукт питания содержит углеводы, а указанный пригодный в пищу полимерный гидрогель заменяет по крайней ...

Bindemittelzusammensetzung bzw. Trägerzusammensetzung

PHARMAZEUTISCHE ZUSAMMENSETZUNGEN MIT VERBESSERTER LEISTUNG ENTHALTEND EIN HPMCA POLYMER

ALKENYL OR ALKYL SUCCINIC ACID ESTER ABSTENTION WASSERLOESLICHE OF CELLULOSEETHER.

POLYMER/CELLULOSE ESTER COMPOSITION

Hair fixatives including starch ester based polyglucose polymers

WATER-SOLUBLE, LOW SUBSTITUTION HYDROXYETHYLCELLULOSE, DERIVATIVES THEREOF, PROCESS OF MAKING, AND USES THEREOF

본 발명은 히드록시에틸 몰 치환도 (HE-MS)가 약 0.7 내지 1.3인 수용성 히드록시에틸셀룰로스 (HEC) 및 이의 유도체에 관한 것이다. 상기 HEC는 수성 시스템을 증점시키는데 있어서 종래 기술의 HEC 제품보다 더욱 효율적이며, 낮은 수 활성 시스템에서 독특한 유동학적 특성을 나타낸다. 상기 HEC는 비치환 무수 글루코스 삼량체 비율 (U3R)이 0.21 미만이고, 수 용해도가 90 중량％를 초과함으로써 종래 기술 및 시판되는 HEC 제품과 차별화될 수 있다. 또한 본 발명은 수용성 저치환 HEC의 제조를 위한 독특한 연속적 가성 환원 히드록시에틸화 방법, 및 기능성 시스템에서의 이의 용도에 관한 것이다. The present invention relates to water soluble hydroxyethylcellulose (HEC) and derivatives thereof having a hydroxyethyl molar substitution degree (HE-MS) of about 0.7 to 1.3. The HEC is more efficient than prior art HEC products for thickening aqueous systems and exhibits unique rheological properties in low water active systems. The HECs can be differentiated from conventional and commercially available HEC products by having an unsubstituted anhydroglucose trimer ratio (U3R) of less than 0.21 and a water solubility of greater than 90% by weight. The present invention also relates to a unique continuous caustic reduced hydroxyethylation process for the preparation of water soluble low substituted HECs, and to their use in functional systems. 수용성 저치환 히드록시에틸셀룰로스, 히드록시에틸 몰 치환도, 비치환 삼량체 비율, 수 용해도 Water-soluble low-substituted hydroxyethylcellulose, hydroxyethyl molar substitution degree, unsubstituted trimer ratio, water solubility

체중 관리 및 혈당 조절 개선을 위한 방법 및 조성물

... 본 발명은 체중 관리 및 혈당 조절에 유용한 방법, 조성물 및 변형된 식품 또는 식품재료를 제공한다.

Cellulose complex

The present invention relates to a cellulose composite in which it is difficult for separation or coagulation to occur, and in greater detail, relates to the above cellulose composite, wherein the cellulose composite comprises cellulose and one or more types of aqueous carboxymethyl cellulose and the tan[delta] of an aqueous dispersion in which the cellulose composite has been dispersed at 1 mass% in ion-exchanged water is at most 0.6.

ACETYLATED CELLULOSE ETHER, METHOD FOR PREPARING SAME, AND ARTICLE COMPRISING THE ACETYLATED CELLULOSE ETHER

Disclosed are an acetylated cellulose ether, a method for preparing same, and an article comprising same. The disclosed acetylated cellulose ether has a degree of substitution (DS) by an alkyl group of 1-2, a degree of molar substitution (MS) by a hydroxyl alkyl group of 0-1, a degree of substitution (DS) by an acetyl group of 1-2; and an apparent density of 0.1-0.4.

HYDROXYPROPYL METHYL CELLULOSE PHTHALATE AND METHOD FOR PRODUCING THE SAME

There is provided a method for producing hydroxypropyl methyl cellulose phthalate (HPMCP), including an esterification step of reacting hydroxypropyl methyl cellulose with a carboxybenzoylating agent in the presence of an aliphatic carboxylic acid in a kneader reactor equipped with two or more stirring blades rotating around their own axes and orbitally revolving, to obtain a reaction product solution containing HPMCP; a precipitation step of precipitating the HPMCP by mixing the reaction product solution with water to obtain a suspension of the precipitated HPMCP; and a washing and recovery step of washing the HPMCP in the suspension and recovering the washed HPMCP. Further, there is provided HPMCP having yellowness at 20° C. of 10.0 or less, as determined in a 10% by mass solution of the HPMCP in acetone.

Composition for hot-melt extrusion and method for producing hot-melt extrusion product using same

Provided are a composition for hot-melt extrusion which can be hot-melt extruded at a temperature lower than a conventional temperature and therefore free of heat-induced deactivation of a drug; and a method for producing a hot-melt extrusion product which is simpler than a spray-drying method. More specifically, provided is a composition for hot-melt extrusion including a drug and hypromellose acetate succinate (HPMCAS) having a hydroxypropoxy molar substitution of 0.40 or more. Also provided is a method for producing a hot-melt extrusion product including a step of hot-melt extruding a composition for hot-melt extrusion including a drug and hypromellose acetate succinate having a hydroxypropoxy molar substitution of 0.40 or more at a hot-melt temperature of melting temperature of the hypromellose acetate succinate or higher, or at a hot-melt temperature equal to or higher than a temperature at which both the hypromellose acetate succinate and the drug become melted.

Hair fixatives including starch ester based polyglucose polymers

A hair fixative composition includes at least one carboxylated starch ester based polyglucose polymer, an alcohol based solvent system, and a cosmetically acceptable additive, wherein the polyglucose polymer is soluble in the alcohol based solvent system. The polyglucose polymer is obtained by reacting at least one starch ester with at least one anhydride.

LOW-MOLECULAR WEIGHT CELLULOSE-MIXED ESTERS AND THEIR USE AS LOW VISCOSITY BINDERS AND MODIFIERS IN COATING COMPOSITIONS

PROBLEM TO BE SOLVED: To provide low-molecular weight cellulose-mixed esters that has low degree of polymerization and are useful in coating and ink compositions as low viscosity binder resins and rheology modifiers. SOLUTION: This invention relates to cellulose-mixed esters having a total degree of substitution per anhydroglucose unit of from about 3.08 to about 3.50, and having the following substitutions: a degree of substitution per anhydroglucose unit of hydroxyl of no more than about 0.70; a degree of substitution per anhydroglucose unit of C3-C4 esters from about 0.80 to about 1.40, and a degree of substitution per anhydroglucose unit of acetyl of from about 1.20 to about 2.34. The mixed esters exhibit an inherent viscosity from about 0.05 to about 0.12 dL/g, as measured in a 60/40 (wt./wt.) solution of phenol/tetrachloroethane at 25[deg.] °C; a number average molecular weight (Mn) of from about 1,000 to about 5,600; a weight average molecular weight (Mw) of from about 1,500 to about ...

ВОДОРАСТВОРИМАЯ НИЗКОЗАМЕЩЕННАЯ ГИДРОКСИЭТИЛЦЕЛЛЮЛОЗА, ЕЕ ПРОИЗВОДНЫЕ, СПОСОБ ЕЕ ПОЛУЧЕНИЯ И ПРИМЕНЕНИЕ

FIELD: chemistry. SUBSTANCE: invention relates to water-soluble hydroxyethyl cellulose and derivatives thereof. Hydroxyethyl cellulose and derivatives thereof are characterised by ratio of unsubstituted trimers less than approximately 0.21, hydroxyethyl molar substitution between approximately 0.7 and 1.3 and water-solubility of over 90%. Hydroxyethyl cellulose is obtained using a suspension method. Cellulose, water and alkali are mixed and react in an organic solvent. Molar ratio of water to anhydroglucose in the prepared alkaline cellulose mixture lies between approximately 5 and 35, and molar ratio of alkali to anhydroglucose is greater than approximately 1.6. Ethylene oxide is added. A sufficient amount of acid is continuously added so as to reduce the molar ratio of alkali to anyhydroglucose to at least approximately 0.4 and preferably higher than approximately 0.04 while simultaneously reacting ethylene oxide with alkaline cellulose. If needed, at least one deriving agent is added to obtain modified hydroxyethyl cellulose. A viscosity lowering agent is then added. This water-soluble hydroxyethyl cellulose and its derivatives are used in compositions for personal care agents, compositions for household care agents, pharmaceutical compositions, building compositions, emulsion polymerisation compositions, compositions of working fluids for oil fields, compositions of working fluids for civil engineering, compositions for coating paper, compositions for making paper, compositions for applying architectural coatings, compositions for applying industrial coatings, compositions for printing ink, adhesive compositions and compositions for processing and extracting minerals. EFFECT: obtained hydroxyethyl cellulose and its derivatives is more efficient when concentrating aqueous systems than existing hydroxyethyl cellulose products, and demonstrates unique rheological properties in systems with low water activity. 34 cl, 8 ex, 16 tbl, 24 ex, 1 dwg РОССИЙСКАЯ ФЕДЕРАЦИЯ ( ...

PHARMACEUTICAL COMPOSITIONS WITH IMPROVED ACHIEVEMENT CONTAINING A HPMCA POLYMER

Methods and compositions for weight management and for improving glycemic control

The present invention provides methods, compositions and modified foods and foodstuffs useful for weight management and glycemic control.

Preparation method of solvent-free water-dispersible hydroxypropyl methly cellulose phthalate nanoparticle

Polysaccharide, neutralized and polysaccharide composition containing same

Polysaccharide. il a des groupes hydrophile fonctionnels et des groupes nitrate de la manière suivante: (CF DESSIN DANS BOPI) X et Y représentant le nombre de groupes hydroxyle fonctionnels et de groupes nitrate par motif répétitif du polysaccharide respectivement. Industrie du papier. Polysaccharide. it has functional hydrophilic groups and nitrate groups as follows: (CF DRAWING IN BOPI) X and Y representing the number of functional hydroxyl groups and nitrate groups per repeating unit of the polysaccharide respectively. Paper industry.

FLAME RETARDANT CELLULOSE ESTER FORMULATION

The present invention relates to a cellulose ester formulation comprising phosphorus-containing propionic acid derivatives as a flame retarding plasticizer. The cellulose ester formulation of the present invention comprises: a) at least one type of cellulose ester; and b) at least one type of phosphorus-containing propionic acid derivatives represented by chemical formula (I). Surprisingly, the cellulose ester formulation does not require an additional plasticizer, and obtains the same level of flame retardancy as the prior art without a need of a halogen compound or aryl phosphate. COPYRIGHT KIPO 2016 ...

가열 용융 압출용 조성물 및 이를 이용한 가열 용융 압출 성형물의 제조 방법

종래보다도 낮은 온도에서 가열 용융 압출함으로써, 열 등에 의한 약물의 실활이 없는, 가열 용융 압출 조성물 및 스프레이 드라이법보다도 간편한 방법에 의해 가열 용융 압출 성형물이 얻어지는 가열 용융 압출 성형물의 제조 방법을 제공한다. 구체적으로는 히드록시프로폭시기의 몰 치환도가 0.40 이상인 히프로멜로오스아세트산에스테르숙신산에스테르(HPMCAS)와 약물을 적어도 포함하는 가열 용융 압출용 조성물을 제공한다. 또한, 히드록시프로폭시기의 몰 치환도가 0.40 이상인 히프로멜로오스아세트산에스테르숙신산에스테르와 약물을 적어도 포함하는 가열 용융 압출용 조성물을 히프로멜로오스아세트산에스테르숙신산에스테르의 용융 온도 이상, 또는 히프로멜로오스아세트산에스테르숙신산에스테르 및 약물과 함께 용융하게 되는 온도 이상의 가열 용융 온도에서 가열 용융하고, 압출하는 공정을 적어도 포함하는 가열 용융 압출 성형물의 제조 방법을 제공한다. The present invention provides a method for producing a hot-melt extruded product in which a heated melt-extruded product is obtained by a method that is simpler than a heated melt-extruded composition and a spray-dry method without thermal deformation of the drug by heating and melt- Specifically, there is provided a composition for hot melt extrusion comprising at least a hydromoroxacetic ester succinic acid ester (HPMCAS) having a molar substitution degree of a hydroxypropoxy group of 0.40 or more and a drug. The composition for hot melt extrusion containing at least a hydromoroxacetic ester succinic acid ester having a molar substitution degree of the hydroxypropoxy group of not less than 0.40 and a drug is heated at a temperature not lower than the melting temperature of the hydromelose acetic acid ester succinic acid ester, Meloxacetate ester succinic ester and meloxic acid ester succinic acid ester together with the drug at a heating and melting temperature equal to or higher than a temperature at which the meloxic acid ester succinic acid ester and the drug are melted together, and extruding the melted extrudate.

composições de éster de celulose/elastômero, artigo, e, processo para produzir uma composição de éster de celulose/elastômero

WATER-SOLUBLE, LOW SUBSTITUTION HYDROXYETHYLCELLULOSE, DERIVATIVES THEREOF, PROCESS OF MAKING, AND USES THEREOF

This invention relates to water-soluble hydroxyethylcelluloses (HECs) and derivatives thereof having a hydroxyethyl molar substitution (HE- MS) from about 0.7 to 1.3. These HECs are more efficient in thickening aqueous systems than prior art HEC products and show unique rheology in low water activity systems. These HECs can be distinguished from prior art and commercial HEC products by having an unsubstituted anhydroglucose trimer ratio (U3R) less than 0.21 and a water solubility greater than 90 wt %. This invention also relates to a unique continuous caustic reduction hydroxyethylation process for making the water-soluble, lowly substituted HECs and uses thereof in functional systems.

NOVEL ESTERIFIED CELLULOSE ETHERS OF VERY HIGH MOLECULAR WEIGHT

Esterified cellulose ethers which comprise (i) groups of the formula -C(O) - R - COOA or (ii) a combination of aliphatic monovalent acyl groups and groups of the formula -C(O) - R - COOA, wherein R is a divalent aliphatic or aromatic hydrocarbon group and A is hydrogen or a cation, which have a viscosity of up 50 mPa.s, measured as a 10 wt% solution of the esterified cellulose ether in acetone at 20°C, and a weight average molecular weight Mw of at least 220,000 Dalton, or which have a viscosity of up 100 mPa.s, measured as a 10 wt% solution of the esterified cellulose ether in acetone at 20°C, and a weight average molecular weight Mw of at least 310,000 Dalton are useful for preparing solid dispersions comprising drugs.

PREPARATION METHOD OF ACETYLATED CELLULOSE ETHER, AND ACETYLATED CELLULOSE ETHER PREPARED THEREBY

Disclosed is a preparation method of an acetylated cellulose ether, and an acetylated cellulose ether prepared thereby. The preparation method of an acetylated cellulose ether comprises the following steps: dissolving an acetylated cellulose ether in an organic solvent to obtain a mixture containing an acetylated cellulose ether solution; removing an insoluble component which does not dissolve in the organic solvent, from the mixture; and injecting the mixture into water to precipitate an acetylated cellulose ether. An acetylated cellulose ether prepared by the method has a turbidity of less than 40 FTU.

CROSSLINKABLE COATING SYSTEMS CONTAINING CARBOXYALKYLCELLULOSE ESTERS

An aminoplast crosslinker system is disclosed having improved cure speed as measured by mar resistance and block and print resistance test results. A carboxyalkyl cellulose ester, such as carboxymethyl cellulose acetate butyrate, is dissolved in a solvent, such as methanol or ethanol, and subsequently blended with an aminoplast crosslinker. This mixture may be used as such, or may be added to a mixture containing an alkyd resin or any other compatible polymer. The finished mixture can then be catalyzed with PTSA or any other catalyst material. In a coating, the system provides dramatically improved cure response and print and block resistance over a crosslinker containing an acrylic polyol or Styrene Allyl Alcohol, while at the same time providing improved flow and leveling.

METHOD FOR PRODUCING HYPROMELLOSE ACETATE SUCCINATE

There is provided a method for producing hypromellose acetate succinate (HPMCAS), the method not requiring any special device and facilitating removal of impurities. More specifically, there is provided a method for producing HPMCAS, including an esterification step of esterifying hypromellose with an acetylating agent and a succinoylating agent in the presence of an aliphatic carboxylic acid to obtain a reaction product solution containing HPMCAS; a precipitation step of precipitating the HPMCAS by mixing the reaction product solution with water to obtain a suspension of the precipitated HPMCAS; a neutralization step of neutralizing the suspension with a basic substance to obtain a neutralized suspension; and a washing step of washing the HPMCAS contained in the neutralized suspension to obtain the washed HPMCAS.

BINDER FOR LITHIUM ION BATTERIES, AND ELECTRODE AND SEPARATOR USING SAME

Provided is a nonaqueous binder for electrodes or separators, which is used in a lithium ion battery that has excellent cycle life characteristics at high temperatures. A nonaqueous binder for electrodes or separators of lithium ion batteries, which is obtained by complexing cellulose nanofibers and a thermoplastic fluororesin, and which is characterized in that the cellulose nanofibers have a fiber size (diameter) of from 0.002 μm to 1 μm (inclusive), a fiber length of from 0.5 μm to 10 mm (inclusive), and an aspect ratio ((fiber length of cellulose nanofibers)/(fiber diameter of cellulose nanofibers)) of from 2 to 100,000 (inclusive). 1. A composite nonaqueous binder of a cellulose nanofiber and a thermoplastic fluororesin for an electrode or a separator of a lithium ion battery ,wherein the cellulose nanofiber is a cellulose having a fiber diameter (diameter) of 0.002 □m or more and 1 □m or less, a fiber length of 0.5 □m or more and 10 mm or less, and an aspect ratio (fiber length of the cellulose nanofiber/fiber diameter of the cellulose nanofiber) of 2 or more and 100,000 or less.2. The binder according to claim 1 , wherein claim 1 , when the total amount of solid contents of the cellulose nanofiber and the thermoplastic fluororesin is taken as 100 mass % claim 1 , the cellulose nanofiber is contained in an amount of 5 mass % or more and 80 mass % or less claim 1 , and the thermoplastic fluororesin is contained in an amount of 20 mass % or more and 95 mass % or less.3. The binder according to claim 1 , wherein the cellulose nanofiber comprises a cellulose nanofiber subjected to polybasic acid semi-esterification treatment to replace some of hydroxyl groups with carboxyl groups.4. The binder according to claim 1 , wherein the cellulose nanofiber comprises a cellulose nanofiber subjected to ethylene oxide addition treatment or propylene oxide addition treatment.5. The binder according to claim 1 , wherein the thermoplastic fluororesin comprises a polyvinylidene ...

Hydroxypropyl methyl cellulose acetate succinate with enhanced acetate and succinate substitution

Disclosed are polymers of hydroxypropyl methyl cellulose acetate succinate (HPMCAS) with unique degrees of substitution of hydroxypropoxy, methoxy, acetyl, and succinoyl groups. When used in making compositions comprising a low-solubility active agent and such polymers, the polymers provide increased aqueous concentrations and/or improved physical stability of the active agent.

Cellulose ester/elastomer compositions

A cellulose ester composition is provided comprising at least one cellulose ester and at least one additive selected from the group consisting of a compatibilizer, and a plasticizer. Processes for producing the cellulose ester composition are also provided. In another embodiment, a cellulose ester/elastomer composition is provided comprising at least one elastomer, at least one cellulose ester; and at least one additive; wherein the additive is at least one selected from the group consisting of a compatibilizer and a plasticizer. Processes for producing the cellulose ester/elastomer composition is also provided as well as articles comprising the cellulose ester/elastomer composition.

Pharmaceutical Compositions With Enhanced Performance and Improved Processability

The presently disclosed and claimed inventive concept(s) relates to a polymer for enhancing drug performance and improving processability. Specifically, the polymer comprises hydroxypropyl methyl cellulose acetate succinate (HPMC-AS). On the HPMC-AS, the percentage of total succinoyl degree of substitution is less than 12% at C6-OH position and greater than 53% at C3-OH, and the percentage of total acetyl degree of substitution is greater than 32% at C6-OH position.

BULK MATERIAL COVER COMPOSITIONS AND METHODS OF APPLYING

A cover material for a bulk material pile and method for applying the cover material are disclosed. The cover composition comprises liquid, cement and/or fly ash, fiber, water dispersible polymer and acid.

CELLULOSE DERIVATIVE, RESIN COMPOSITION, MOLDED ARTICLE AND PROCESS FOR PRODUCTION THEREOF, AND HOUSING FOR ELECTRIC AND ELECTRONIC DEVICE

A cellulose derivative, contains A) a hydrocarbon group; B) a group containing an acyl group: -CO-RB and an ethyleneoxy group: -C2H4-O- (RB represents a hydrocarbon group); and C) an acyl group: -CO-RC (RC represents a hydrocarbon group).

LOW MOLECULAR WEIGHT CELLULOSE MIXED ESTERS AND THEIR USE AS LOW VISCOSITY BINDERS AND MODIFIERS IN COATING COMPOSITIONS

Cellulose mixed esters are disclosed having low molecular weights and low degrees of polymerization. These new cellulose mixed esters include cellulose acetate propionate and cellulose acetate butyrate. The esters exhibit solubility in a wide range of organic solvents with minimal viscosity increase, are compatible with a wide variety of resins, and are useful in coatings and inks compositions as binder resins and rheology modifiers.

アセテートおよびサクシネートの置換が向上されたヒドロキシプロピルメチルセルロースアセテートサクシネート

СПОСОБЫ И КОМПОЗИЦИИ ДЛЯ РЕГУЛИРОВАНИЯ ВЕСА И ДЛЯ УЛУЧШЕНИЯ ГЛИКЕМИЧЕСКОГО КОНТРОЛЯ

1. Модифицированный пищевой продукт или продукт питания, содержащий пригодный в пищу полимерный гидрогель.2. Модифицированный пищевой продукт или продукт питания по п. 1, отличающийся тем, что указанный пригодный в пищу полимерный гидрогель имеет коэффициент набухания 40 или больше.3. Модифицированный пищевой продукт или продукт питания по п. 1, отличающийся тем, что указанный пригодный в пищу полимерный гидрогель имеет коэффициент набухания 80 или больше.4. Модифицированный пищевой продукт или продукт питания по п. 1, отличающийся тем, что указанный пригодный в пищу полимерный гидрогель имеет модуль упругости не менее 200 Па.5. Модифицированный пищевой продукт или продукт питания по п. 1, отличающийся тем, что указанный пригодный в пищу полимерный гидрогель имеет вязкость не менее 15 s.6. Модифицированный пищевой продукт или продукт питания по п. 1, отличающийся тем, что пищевой продукт или продукт питания содержит углеводы, а указанный пригодный в пищу полимерный гидрогель заменяет по крайней мере часть углеводного содержимого по отношению к соответствующему обыкновенному пищевому продукту или продукту питания.7. Модифицированный пищевой продукт или продукт питания по п. 6, отличающийся тем, что указанный пищевой продукт или продукт питания содержит углеводы из зерна, хлебных злаков или крахмалистых овощей.8. Модифицированная мука, содержащая пригодный в пищу полимерный гидрогель, выбранный из пригодных в пищу полимерных гидрогелей, сформированных поперечной сшивкой гидрофильного полимера поликарбоксильной кислотой и пригодных в пищу полимерных гидрогелей.9. Модифицированная мука по п. 8, отличающаяся тем, что ука РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 2014 110 522 A (51) МПК A23L 1/05 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ЗАЯВКА НА ИЗОБРЕТЕНИЕ (21)(22) Заявка: 2014110522/13, 19.03.2014 (71) Заявитель(и): УАН С.Р.Л. (IT), ДЖЕЛЕЗИС АйПи, ЛПи (US) Приоритет(ы): (30) Конвенционный приоритет: (72) Автор(ы): САННИНО Алессандро (IT), ...

ФАРМАЦЕВТИЧЕСКИЕ КОМПОЗИЦИИ, ОБЛАДАЮЩИЕ ПОВЫШЕННОЙ ЭФФЕКТИВНОСТЬЮ И УЛУЧШЕННОЙ ОБРАБАТЫВАЕМОСТЬЮ

ALKENYL- ODER ALKYLBERNSTEINSAEUREESTER ENTHALTENDE WASSERLOESLICHE CELLULOSEETHER.

New water-soluble cellulose ether derivs. (I) are mfd. by reaction of 100 pts.wt. of a water-soluble cellulose ether (II) with 3-30 (pref. 5-25) pts.wt. 8-18C (pref. 10-14C) alk(en)ylsuccinic anhydride (III), in the absence of water and of alkali, at elevated temp., under conditions such that 1-8 wt.% of (III) (w.r.t. (II) reacts with (II). Reaction is carried out at 40-150 (pref. 60-110) deg.C for 0.5-12 (pref. 2-6) hrs; pref. 3-6 wt.% of (III) reacts with (II). (I) are mfd. e.g. by dissolving (III) in an aprotic solvent and spraying onto solid (II), with agitation.

Improvements in and relating to emulsion paints

Thixotropic emulsion paints are produced by heating an aqueous emulsion paint containing a cellulose ether as thickener and polyvinyl acetate as binder, in a closed vessel at 45 DEG to 65 DEG C. for at least 2 days. Conventional ingredients which may be included are fungicides such as mercury dinaphthymethane disulphonate and tributyl tin acetate, resinate or oxide, bactericides such as p-chloro-m-cresol and sodium pentachlorophenate, corrosion inhibitors such as sodium benzoate, wetting agents such as sodium hexametaphosphate, unspecified plasticizers and pigments such as titanium dioxide and china clay.

LOW-MOLECULAR CARBOXYALKYLCELLULOSEESTER AND THEIR USE AS NIEDERVISKOSE BONDING AGENTS AND MODIFYING AGENT IN COATING COMPOSITIONS

INTERLACE-CASH POLYMER DISPERSIONS, PROCEDURES FOR THEIR PRODUCTION AND USE

Adhesive composition or structure

PHARMACEUTICAL COMPOSITIONS WITH ENHANCED PERFORMANCE AND IMPROVED PROCESSABILITY

The presently disclosed and claimed inventive concept(s) relates to a polymer for enhancing drug performance and improving processability. Specifically, the polymer comprises hydroxypropyl methyl cellulose acetate succinate (HPMC-AS). On the HPMC- AS, the percentage of total succinoyl degree of substitution is less than 12% at C6-OH position and greater than 53% at C3-OH, and the percentage of total acetyl degree of substitution is greater than 32% at C6-OH position.

셀룰로오스 에테르의 에스테르를 제조하기 위한 효율적인 방법

The method of producing an esterified cellulose ether is such that a wet cellulosic ether having a water content of at least 10 percent based on the weight of the wet cellulose ether is reacted with an aliphatic monocarboxylic acid anhydride, a dicarboxylic acid anhydride, Can be produced effectively. Further improvements in efficiency and in the reduction of process steps can be achieved in a process for producing esterified cellulose ethers, the process comprising the steps of: a) reacting cellulose with an alkaline substance to produce alkali cellulose B) reacting the produced alkali cellulose with at least one etherifying agent and washing the produced cellulose ether to obtain a wet cellulosic ether having a water content of at least 10 weight percent, and c) Reacting the ether with an aliphatic monocarboxylic acid anhydride and / or a dicarboxylic acid anhydride and with a depolymerization agent.

USE OF CARBOXYALKYL CELLULOSE ESTERS, SUCH AS CARBOXYMETHYL CELLULOSE ACETATE BUTYRATE, TO FORM AQUEOUS DISPERSIONS OF HYDROPHOBIC MATERIALS IN WATER

The present invention relates to methods of dispersing hydrophobic materials into water, using carboxyalkyl cellulose esters such as carboxymethyl cellulose acetate butyrate (CMCAB), and to the resulting aqueous dispersions. The invention relates also to finished coating films made from such dispersions, which exhibit reduced water sensitivity without increasing the film dry time beyond that obtained from aqueous dispersions using conventional surfactants.

Process for producing dispersion of esterified cellulose ether

A process for producing an aqueous composition comprising a dispersed esterified cellulose ether comprises the steps of grinding, in the presence of an aqueous diluent an esterified cellulose ether comprising (i) groups of the formula —C(O)—R—COOA or (ii) a combination of aliphatic monovalent acyl groups and groups of the formula —C(O)—R—COOA, wherein R is a N divalent aliphatic or aromatic hydrocarbon group and A is hydrogen or a cation, blending a salt of a fatty acid with the esterified cellulose ether and choosing the amounts of aqueous diluent, esterified cellulose ether and salt of a fatty acid that the produced aqueous composition comprises at least 20 percent of the dispersed esterified cellulose ether and heating the aqueous composition to a temperature of from 37 to 80 C during or after the grinding step.

Esterified cellulose ethers of low acetone-insoluble content

Esterified cellulose ethers which have i) as ester groups aliphatic monovalent acyl groups or groups of the formula —C(O)—R—COOA or a combination of aliphatic monovalent acyl groups and groups of the formula —C(O)—R—COOA, wherein R is a divalent aliphatic or aromatic hydrocarbon group and A is hydrogen or a cation, and ii) a content of not more than 0.85 weight percent acetone-insoluble esterified cellulose ether particles, when the esterified cellulose ether is present in a mixture of 12.5 weight parts of esterified cellulose ether and 87.5 weight parts of acetone at 21° C., the weight percent acetone-insoluble esterified cellulose ether particles being based on the total weight of the esterified cellulose ether, wherein iii) not more than 14 percent of the acetone-insoluble esterified cellulose ether particles have a particle size of more than 90 micrometers.

PHARMACEUTICAL COMPOSITIONS WITH ENHANCED PERFORMANCE

Pharmaceutical compositions of a low-solubility drug and lower alkanoate-, phthalate- and trimellitate esters of hydroxypropyl methyl cellulose and lower alkanoate- and succinate esters of cellulose and methyl cellulose are disclosed that provide enhanced concentrations of the drug in a use environment.

PREPARATION METHOD OF SOLVENT-FREE WATER-DISPERSIBLE HYDROXYPROPYL METHYL CELLULOSE PHTHALATE NANOPARTICLE

The present invention relates to a preparation method of solvent-free water-dispersible hydroxypropyl methyl cellulose phthalate nanoparticle, and more particularly, to a preparation method of solvent-free water-dispersible hydroxypropyl methyl cellulose phthalate nanoparticle, which is environment-friendly and advantageous in disintegration and dissolution when used as an enteric coating material, which is prepared by obtaining suitable hydroxypropyl methyl cellulose phthalate (HPMCP) particle through aqueous emulsification process and regulating content of remaining electrolyte through ion exchange process.

LOW MOLECULAR WEIGHT CELLULOSE MIXED ESTERS AND THEIR USE AS LOW VISCOSITY BINDERS AND MODIFIERS IN COATING COMPOSITIONS

ФИКСАТОРЫ ДЛЯ ВОЛОС, ВКЛЮЧАЮЩИЕ ПОЛИГЛЮКОЗНЫЕ ПОЛИМЕРЫ НА ОСНОВЕ СЛОЖНЫХ ЭФИРОВ КРАХМАЛА

FIELD: chemistry.SUBSTANCE: group of inventions relates to hair care. Hair fixation composition includes at least one polyglycosic polymer based on carboxylated starch esters, which is soluble in an alcohol-based solvent system, obtained by reacting at least one starch ester with at least two cyclic anhydrides, with the following structure (I):(I),in which R=H, Ror R,or a combination thereof, wherein at least one R is Rand where Ris: -CO-R, where Ris C-C-alkyl group; and Ris: a) -CO-CH-CH (R) -COOH, where R=H or C-Can alkenyl group, or b) -CO-CH=CH-COOH; or c) -CO-CH-C (= CH) -COOH; or d) -CO-CH-COOH, or e) -CO-CH-COOH; and where n = 10–500; solvent system based on alcohols, including at least one C-C-linear alcohol, C-C-trimethyl alcohol or mixture thereof in amount of 15 wt. %; and at least one cosmetically acceptable additive. Also disclosed is a method of producing the composition and use of a polyglucose polymer based on carboxylated starch esters as a hair fixing polymer.EFFECT: group of inventions provides excellent fixation of wave in high humidity conditions.15 cl, 9 tbl, 5 ex РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 2 700 697 C1 (51) МПК A61K 8/34 (2006.01) A61K 8/73 (2006.01) A61K 8/85 (2006.01) A61Q 5/06 (2006.01) C08L 1/32 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ОПИСАНИЕ ИЗОБРЕТЕНИЯ К ПАТЕНТУ (52) СПК A61K 8/34 (2013.01); A61K 8/73 (2013.01); A61K 8/85 (2013.01); A61Q 5/06 (2013.01); C08L 1/32 (2013.01) (21)(22) Заявка: 2016127938, 17.12.2014 (24) Дата начала отсчета срока действия патента: R U 17.12.2014 (72) Автор(ы): БЕВИНАКАТТИ Ханамантса (US) (73) Патентообладатель(и): АКЦО НОБЕЛЬ КЕМИКАЛЗ ИНТЕРНЭШНЛ Б.В. (NL) Дата регистрации: 19.09.2019 20.12.2013 US 61/919,066; 14.02.2014 EP 14155145.7 (45) Опубликовано: 19.09.2019 Бюл. № 26 (85) Дата начала рассмотрения заявки PCT на национальной фазе: 20.07.2016 (86) Заявка PCT: 2 7 0 0 6 9 7 (56) Список документов, цитированных в отчете о поиске: US 3790664 A, 05.02.1974. FR 2778559 ...

СОСТАВ ДЛЯ ПОЛУЧЕНИЯ БИОРАЗЛАГАЕМОЙ ПОЛИМЕРНОЙ ПЛЕНКИ НА ОСНОВЕ ПРИРОДНЫХ МАТЕРИАЛОВ

FIELD: biochemistry. SUBSTANCE: invention relates to production of biodegradable polymer film for use in food industry, in particular in dairy industry, for packing such products as curd, soft cheeses and butter. Composition contains gelatin, carrageenan, agar-agar and / or hydroxypropyl methylcellulose and water. EFFECT: invention provides a biodegradable polymer film with high strength and high degree of decomposition (not more than 1–2 months) for packaging food products and prolonging their storage life. 4 cl, 8 tbl, 3 ex РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 2 693 776 C1 (51) МПК C08L 1/32 (2006.01) C08L 101/16 (2006.01) C08J 5/18 (2006.01) C08L 5/12 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ОПИСАНИЕ ИЗОБРЕТЕНИЯ К ПАТЕНТУ (52) СПК C08L 1/32 (2019.02); C08L 5/12 (2019.02); C08L 101/16 (2019.02); C08J 5/18 (2019.02) (21)(22) Заявка: 2018133758, 24.09.2018 (24) Дата начала отсчета срока действия патента: Дата регистрации: 04.07.2019 (45) Опубликовано: 04.07.2019 Бюл. № 19 2223653 C2, 20.02.2004. EP 1580228 A1, 28.09.2005. RU 2649981 C1, 06.04.2018. RU 2375877 C2, 20.12.2009. EP 3109272 A1, 28.12.2016. (54) СОСТАВ ДЛЯ ПОЛУЧЕНИЯ БИОРАЗЛАГАЕМОЙ ПОЛИМЕРНОЙ ПЛЕНКИ НА ОСНОВЕ ПРИРОДНЫХ МАТЕРИАЛОВ (57) Реферат: Изобретение относится к созданию гидроксипропилметилцеллюлозу и воду. биоразлагаемой полимерной пленки для Изобретение обеспечивает получение использования в пищевой промышленности, в биоразлагаемой полимерной пленки с высокой частности в молочной промышленности, для прочностью и высокой степенью разложения (не упаковывания таких продуктов, как творог, более 1-2 месяцев) для упаковки пищевых мягкие сыры и сливочное масло. Состав содержит продуктов и продления их сроков хранения. 3 з.п. желатин, каррагинан, агар-агар и/или ф-лы, 8 табл., 3 пр. R U 2 6 9 3 7 7 6 (56) Список документов, цитированных в отчете о поиске: RU 2604223 C1, 10.12.2016. RU Стр.: 1 C 1 C 1 Адрес для переписки: 650000, г. Кемерово, ул. Красная, 6, КемГУ, Центр ...

METHODS AND COMPOSITIONS FOR WEIGHT MANAGEMENT AND FOR IMPROVING GLYCEMIC CONTROL

The present invention provides methods, compositions and modified foods and foodstuffs useful for weight management and glycemic control.

Cellulose derivative and process for production thereof, resin composition, molded article and process for production thereof, and housing for electronic device

Disclosed is a cellulose derivative having good thermal plasticity, strength and elongation at break and is suitable for molding. Also disclosed is a resin composition. The cellulose derivative is produced by substituting at least some of hydrogen atoms in hydroxy groups contained in cellulose by a hydrocarbon group and an aliphatic oxycarbonyl group or an aromatic oxycarbonyl group.

체중 관리 및 혈당 조절 개선을 위한 방법 및 조성물

본 발명은 체중 관리 및 혈당 조절에 유용한 방법, 조성물 및 변형된 식품 또는 식품재료를 제공한다. The present invention provides methods, compositions and modified foods or food materials useful for weight management and blood glucose control.

HYDROXYPROPYL METHYL CELLULOSE ACETATE SUCCINATE WITH ENHANCED ACETATE AND SUCCINATE SUBSTITUTION

Cellulose complex

COMPOSITION FOR HEAT MELT EXTRUSION AND METHOD FOR PRODUCING HEAT MELT EXTRUDED PRODUCT USING SAME

Provided is a composition for heat melt extrusion, which contains at least a medicament and a hypromellose acetate succinate (HPMCAS) that has a degree of molar substitution of hydroxypropoxy groups of 0.40 or more and a ratio (molar ratio) of acetyl groups to succinyl groups of less than 1.6. Also provided is a method for producing a heat melt extruded product, which comprises at least a step wherein a composition for heat melt extrusion containing at least a medicament and a hypromellose acetate succinate that has a degree of molar substitution of hydroxypropoxy groups of 0.40 or more and a ratio (molar ratio) of acetyl groups to succinyl groups of less than 1.6 is heated, melted and extruded at a heat melt temperature that is not less than the melting temperature of the hypromellose acetate succinate or not less than the temperature at which both the hypromellose acetate succinate and the medicament are melted.

AQUEOUS DISPERSIONS UTILIZING CARBOXYALKYL CELLULOSE ESTERS AND WATER REDUCIBLE POLYMERS

Aqueous dispersions containing hydrophobic materials that are useful as reduced volatile organic content may be utilized as a coating, a stain, a resin, a polymer, or an additive. Specifically, the aqueous dispersion may contain one or more of a carboxyalkyl cellulose ester, such as carboxymethyl cellulose acetate butyrate, a fluorosurfactant, such as a polyoxetane fluorosurfactant or a fluoroaliphatic polymeric ester based surfactant, a water dispersible resin, and optionally, a C-11 ketone and/or surfactant.

PREPARATION METHOD OF ENTERIC AQUEOUS DISPERSED HYDROXYPROPYL METHYLCELLULOSE PHTHALATE NANOPARTICLE

The present invention relates to a process for preparing enteric water-dispersible hydroxypropyl methylcellulose phthalate nanoparticles, in particular, to a process for preparing enteric water-dispersible hydroxypropyl methylcellulose phthalate nanoparticles in a cost-effective and time-saving manner, in which hydroxypropyl methylcellulose phthalate nanoparticles are prepared without using an emulsifier, wherein the residual electrolyte content is adjusted through ion exchange step for a short period of time followed by the addition of a plasticizer, thereby the environment-friendly water-dispersible hydroxypropyl methylcellulose phthalate nanoparticles showing excellent film properties and enteric coating properties are prepared.

AQUEOUS COMPOSITION COMPRISING DISPERSED ESTERIFIED CELLULOSE ETHER

An aqueous composition which is useful for producing coatings and capsule shells comprises a) dispersed particles of an esterified cellulose ether comprising (i) groups of the formula —C(O)—R—COOA or (ii) a combination of aliphatic monovalent acyl groups and groups of the formula —C(O)—R—COOA, wherein R is a divalent hydrocarbon group and A is hydrogen or a cation, and the total degree of ester substitution is more than 0.70, and b) an esterified cellulose ether comprising aliphatic monovalent acyl groups and groups of the formula —C(O)—R—COOH, R being a divalent hydrocarbon group, wherein I) the degree of neutralization of the groups —C(O)—R—COOH is not more than 0.4, II) the total degree of ester substitution is from 0.03 to 0.70, and III) the esterified cellulose ether b) has a solubility in water of at least 2.0 weight percent at 2° C. 2. The aqueous composition of comprising at least 15 percent of the dispersed particles a) claim 1 , based on the total weight of the aqueous composition.3. The aqueous composition of comprising at least 2 percent of the esterified cellulose ether b) claim 1 , based on the total weight of the aqueous composition.4. The aqueous composition of claim 1 , wherein the median particle size claim 1 , d50 claim 1 , of the dispersed esterified cellulose ether particles a) is up to 7 micrometers claim 1 , such median particle size (d50) being the size at which 50 volume percent of the particles have a smaller equivalent diameter and 50 volume percent have a larger equivalent diameter.5. The aqueous composition of claim 1 , wherein the total degree of ester substitution of the dispersed esterified cellulose ether particles a) is from 0.75 to 1.10.6. The aqueous composition of claim 1 , wherein the total degree of ester substitution of the esterified cellulose ether b) is from 0.20 to 0.60.7. The aqueous composition of wherein the aqueous composition additionally comprises c) 0.05 to 20 percent of a salt of a fatty acid claim 1 , based on the ...

Aqueous dispersions utilizing carboxyalkyl cellulose esters and water reducible polymers

Aqueous dispersions containing hydrophobic materials that are useful as reduced volatile organic content may be utilized as a coating, a stain, a resin, a polymer, or an additive. Specifically, the aqueous dispersion may contain one or more of a carboxyalkyl cellulose ester, such as carboxymethyl cellulose acetate butyrate, a fluorosurfactant, such as a polyoxetane fluorosurfactant or a fluoroaliphatic polymeric ester based surfactant, a water dispersible resin, and optionally, a C-11 ketone and/or surfactant.

CELLULOSE ESTER/ELASTOMER COMPOSITIONS

A cellulose ester composition is provided comprising at least one cellulose ester and at least one additive selected from the group consisting of a compatibilizer, and a plasticizer. Processes for producing the cellulose ester composition are also provided. In another embodiment, a cellulose ester/elastomer composition is provided comprising at least one elastomer, at least one cellulose ester; and at least one additive; wherein the additive is at least one selected from the group consisting of a compatibilizer and a plasticizer. Processes for producing the cellulose ester/elastomer composition is also provided as well as articles comprising the cellulose ester/elastomer composition.

СПОСОБЫ И КОМПОЗИЦИИ ДЛЯ ОПТИМИЗАЦИИ ВЕСА И ДЛЯ УЛУЧШЕНИЯ УРОВНЯ ГЛЮКОЗЫ В КРОВИ

FIELD: medicine, pharmaceutics. SUBSTANCE: invention refers to modified food applicable for weight management and blood glucose improvement. The modified food contains an edible polymer hydrogel representing a polysaccharide cross-linked with citric acid. What is also presented is a method for increasing control in an individual in need thereof providing oral administration of the above polymer hydrogel into the above individual. EFFECT: invention enables increasing saturation and reducing the amount of consumed food, as well as improving the glycaemic control. 48 cl, 9 dwg, 9 tbl, 32 ex РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (51) МПК A23L 1/05 A23L 1/29 A23L 2/39 A23L 2/52 A21D 2/08 (13) 2 518 262 C2 (2006.01) (2006.01) (2006.01) (2006.01) (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ОПИСАНИЕ (21)(22) Заявка: ИЗОБРЕТЕНИЯ К ПАТЕНТУ 2011124705/13, 18.11.2009 (24) Дата начала отсчета срока действия патента: 18.11.2009 Приоритет(ы): (30) Конвенционный приоритет: (72) Автор(ы): САННИНО Алессандро (IT), АМБРОСИО Луиджи (IT), РОН Ейал (US), ЗОХАР Йишай (US) R U (73) Патентообладатель(и): УАН С.Р.Л. (IT), ДЖЕЛЕЗИС АйПи, ЛПи (US) 18.11.2008 US 61/115,759; 11.02.2009 US 61/151,745; 07.04.2009 US 61/167,291 (43) Дата публикации заявки: 10.01.2013 Бюл. № 1 (56) Список документов, цитированных в отчете о поиске: US 2008227944 A1, 18.09.2008. US 2005118326 A1, 02.06.2005 . US 2008095911 A1, 24.04.2008. US 2001006677 A1, 05.07.2005 (86) Заявка PCT: US 2009/064988 (18.11.2009) C 2 C 2 (85) Дата начала рассмотрения заявки PCT на национальной фазе: 20.06.2011 (87) Публикация заявки PCT: 2 5 1 8 2 6 2 WO 2010/059725 (27.05.2010) R U 2 5 1 8 2 6 2 (45) Опубликовано: 10.06.2014 Бюл. № 16 Адрес для переписки: 190000, Санкт-Петербург, ул. Малая Морская, 15, офис 5, ВОХ-сервис 1125, ООО "ПАТЕНТИКА" (54) СПОСОБЫ И КОМПОЗИЦИИ ДЛЯ ОПТИМИЗАЦИИ ВЕСА И ДЛЯ УЛУЧШЕНИЯ УРОВНЯ ГЛЮКОЗЫ В КРОВИ (57) Реферат: Изобретение относится к модифицированным нуждающегося в этом субъекта, ...

ФИКСАТОРЫ ДЛЯ ВОЛОС, ВКЛЮЧАЮЩИЕ ПОЛИГЛЮКОЗНЫЕ ПОЛИМЕРЫ НА ОСНОВЕ СЛОЖНЫХ ЭФИРОВ КРАХМАЛА

РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 2016 127 938 A (51) МПК A61K 8/85 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ЗАЯВКА НА ИЗОБРЕТЕНИЕ (21)(22) Заявка: 2016127938, 17.12.2014 (71) Заявитель(и): АКЦО НОБЕЛЬ КЕМИКАЛЗ ИНТЕРНЭШНЛ Б.В. (NL) Приоритет(ы): (30) Конвенционный приоритет: 20.12.2013 US 61/919,066; 14.02.2014 EP 14155145.7 (72) Автор(ы): БЕВИНАКАТТИ Ханамантса (US) (85) Дата начала рассмотрения заявки PCT на национальной фазе: 20.07.2016 EP 2014/078227 (17.12.2014) (87) Публикация заявки PCT: R U Адрес для переписки: 129090, Москва, ул. Б.Спасская, 25, строение 3, ООО "Юридическая фирма Городисский и Партнеры" (54) ФИКСАТОРЫ ДЛЯ ВОЛОС, ВКЛЮЧАЮЩИЕ ПОЛИГЛЮКОЗНЫЕ ПОЛИМЕРЫ НА ОСНОВЕ СЛОЖНЫХ ЭФИРОВ КРАХМАЛА (57) Формула изобретения 1. Композиция для фиксации волос, включающая: по меньшей мере, один полиглюкозный полимер на основе карбоксилированных сложных эфиров крахмала, полученный взаимодействием, по меньшей мере, одного сложного эфира крахмала с, по меньшей мере, одним циклическим ангидридом; систему растворителей на основе спиртов, где система растворителей на основе спиртов включает, по меньшей мере, один C1-C6- линейный или разветвленный спирт или их смесь; и по меньшей мере, одну косметически приемлемую добавку, где, по меньшей мере, один полиглюкозный полимер на основе карбоксилированных сложных эфиров крахмала является растворимым в системе растворителей на основе спиртов. 2. Композиция по п. 1, где, по меньшей мере, один сложный эфир крахмала получен взаимодействием крахмала, по меньшей мере, с одним вторым ангидридом. 3. Композиция по п. 1 или 2, где, по меньшей мере, один циклический ангидрид выбран из группы, состоящей из янтарного ангидрида, алкенилянтарного ангидрида, малеинового ангидрида, итаконового ангидрида, фталевого ангидрида, тетрагидрофталевого ангидрида и их комбинаций. Стр.: 1 A 2 0 1 6 1 2 7 9 3 8 A WO 2015/091650 (25.06.2015) 2 0 1 6 1 2 7 9 3 8 (86) Заявка PCT: R U (43) Дата публикации заявки: 25.01.2018 ...

Binder and vehicle compositions comprising a neutralized polysaccharide derivative

USE OF CARBOXYALKYL CELLULOSE ESTERS, SUCH AS CARBOXYMETHYL CELLULOSE ACETATE BUTYRATE, TO FORM AQUEOUS DISPERSIONS OF HYDROPHOBIC MATERIALS IN WATER

PHARMACEUTICAL COMPOSITIONS WITH ENHANCED PERFORMANCE

PHARMACEUTICAL COMPOSITIONS WITH ENHANCED PERFORMANCE

Disclosed are polymers of hydroxypropyl methyl cellulose acetate succinate (HPMCAS) and hydroxypropyl methyl cellulose acetate (HPMCA) with unique degrees of substitution of hydroxypropoxy, methoxy, acetyl, and succinoyl groups. When used in making compositions comprising a low-solubility drug and such polymers, the polymers provide enhanced aqueous concentrations and/or improved physical stability.

CELLULOSIC POLYMER NANOPARTICLES AND METHODS OF FORMING THEM

Nanoparticles including a cellulosic polymer and a hydrophobic material and methods for forming them.

MOLDING MATERIAL, MOLDED ARTICLE, METHOD FOR PRODUCING THE SAME, AND HOUSING FOR ELECTRIC AND ELECTRONIC EQUIPMENT

PROBLEM TO BE SOLVED: To provide a molding material and a molded article having excellent rigidity, bending strength, heat resistance, impact resistance, molding processability, and low-temperature impact resistance, and in addition, a molding material and a molded article with excellent falling ball impact strength and Vicat softening temperature. SOLUTION: The molding material contains: a cellulose derivative containing at least one group in which a hydrogen atom of a hydroxyl group in the cellulose is substituted by (A) a hydrocarbon group expressed by -RA and at least one group in which a hydrogen atom of a hydroxyl group is substituted by (B) an acyl group expressed by -CO-RB (where RB represents a hydrocarbon group); and an aliphatic polyester elastomer having an average molecular weight of not less than 10,000. COPYRIGHT: (C)2011,JPO&INPIT ...

REN VERWENDUNG ALS NIEDERVISKOSE BINDEMITTEL UND MODIFIZIERUNGSMITTEL IN BESCHICHTUNGSZUSAMMENSETZUNGEN

ALLERGEN INACTIVATOR

Biodegradable blends and films having nano-structural features

A thermoplastic polymer composition with a tertiary blend of a carbon dioxide-derived polymer, a thermoplastic cellulose derivative, and a thermoplastic compatibilizer is described. The composition can be melt-processed into flexible, thin films that have fine nano-scale structural features in both the cross-directional and machine-directional orientations, for use in various products. The films, which are made from relatively brittle materials, exhibit a greater degree of ductility, elongation capacity, and strength than the primary, original component materials as binary -blends from which the film is made.

PHARMACEUTICAL COMPOSITIONS WITH ENHANCED PERFORMANCE AND IMPROVED PROCESSABILITY

The presently disclosed and claimed inventive concept(s) relates to a polymer for enhancing drug performance and improving processability. Specifically, the polymer comprises hydroxypropyl methyl cellulose acetate succinate (HPMC-AS). On the HPMC- AS, the percentage of total succinoyl degree of substitution is less than 12% at C6-OH position and greater than 53% at C3-OH, and the percentage of total acetyl degree of substitution is greater than 32% at C6-OH position.

BIOPOLYMER COMPOSITIONS AND PRODUCTS THEREOF

This invention relates to biopolymer-based compositions and biopolymer-based formed bodies such as film, sheet, capsule, casing or coating-film or spray thereof. In another embodiment, the invention relates to a process for producing a biopolymer-based starting material and biopolymer-based formed bodies such as cited above, for the manufacture of pharmaceutical, veterinary, food for cosmetic products.

LOW MOLECULAR WEIGHT CARBOXYALKYCELLULOSE ESTERS AND THEIR USE AS LOW VISCOSITY BINDERS AND MODIFIERS IN COATING COMPOSITIONS

成形材料、成形体、及びその製造方法、並びに電気電子機器用筐体

A polysaccharide derivative, a neutralized ploysaccharide derivative and a composition comprising the neutralized polysaccharide derivative

The polysaccharide derivative has hydrophilic functional groups and nitrate groups per one repeating unit in the following range: 0.2 Подробнее

Moisture and oil barrier

Provided is the use of a film of a cellulose ester as a barrier against moisture and oil. The cellulose ester has free hydroxyl groups and ester substituents. The ester substituents are each individually selected from C1 to C6 alkyl ester groups (preferably butyrate). The free hydroxyl groups are present in an amount in the range 15 % to 40 mol%. The film is useful as a barrier layer for food packaging. Also provided is a composition comprising the cellulose ester and a further film-forming material, a packaging material comprising a film of the composition, and a method for manufacturing the packaging material.

METHODS AND COMPOSITIONS FOR WEIGHT MANAGEMENT AND FOR IMPROVING GLYCEMIC CONTROL, COMPRISING CROSS-LINKED, EDIBLE POLYMER HYDROGELS

The present invention provides a modified food or foodstuff comprising an edible polymer hydrogel comprising carboxymethylcellulose crosslinked with citric acid and is in the form of dehydrated particulates individually coated with a moisture barrier. Also provided is the use of a hydrogel for enhancing glycemic control in a subject.

THE POLYSACCHARIDE, POLYSACCHARIDE WHICH NEUTRALIZES AND COMPOSITION COMPRISING THE SAME.

셀룰로스 에스테르 및 셀룰로스 에스테르/엘라스토머 조성물 및 제조 방법

본 발명은 하나 이상의 셀룰로스 에스테르, 및 상용화제 및 가소제로 이루어진 군으로부터 선택된 하나 이상의 첨가제를 포함하는 셀룰로스 에스테르 조성물을 제공한다. 본 발명은 셀룰로스 에스테르 조성물을 제조하는 방법 또한 제공한다. 또다른 구현예에서 하나 이상의 엘라스토머, 하나 이상의 셀룰로스 에스테르 및 하나 이상의 첨가제를 포함하는 셀룰로스 에스테르/엘라스토머 조성물을 제공하고, 여기서 첨가제는 상용화제 및 가소제로 이루어진 군으로부터 선택된 하나 이상이다. 본 발명은 셀룰로스 에스테르/엘라스토머 조성물의 제조 방법 뿐만 아니라 셀룰로스 에스테르/엘라스토머 조성물을 포함하는 물품 또한 제공한다. The present invention provides a cellulose ester composition comprising at least one cellulose ester, and at least one additive selected from the group consisting of compatibilizers and plasticizers. The invention also provides a method of making a cellulose ester composition. In another embodiment, there is provided a cellulose ester / elastomer composition comprising at least one elastomer, at least one cellulosic ester, and at least one additive, wherein the additive is at least one selected from the group consisting of compatibilizers and plasticizers. The present invention also provides articles comprising a cellulose ester / elastomer composition as well as a method of making a cellulose ester / elastomer composition.

Method of preparing acetylated cellulose ether and acetylated cellulose ether prepared by using the method

Water-soluble polysaccharide ethers and their use

The invention relates to modified polysaccharide ethers having a weight-averaged molecular weight of 40000 to 50000 g/mole, zero shear viscosity of more than 10 Pas, and pseudoplasticity of more than 20, obtainable by reacting cellulose-based polysaccharide ether(s) with at least one mesogenic modification agent or modified polysaccharide ethers, obtainable by reacting polysaccharide ether(s) selected from the group consisting of hydroxypropylmethyl cellulose (HPMC), hydroxyethylmethyl cellulose (HEMC), methyl cellulose, and cellulose ethers with methyl and/or ethyl and/or propyl groups and mixtures thereof, with at least one mesogenic modification agent. Said substances can be used to produce gel-like to stable aqueous preparations having viscoelastic flow properties, which are suited for use in the human body, particularly within the scope of ophthalmologic procedures.

Acetylated cellulose ether and articles comprising the same

Acetylated cellulose ether and an article including the same. The acetylated cellulose ether has a degree of substitution (DS) of alkyl group of 1 to 2, a molar substitution (MS) of hydroxyalkyl group of 0 to 1, and a degree of substitution (DS) of acetyl group of 1 to 2.

RESIN COMPOSITION AND MOLDED ARTICLE

A cellulose acetate resin composition having a cellulose acetate ether compound and a stabilizer; 2. The resin composition according to claim 1 ,wherein the specific atomic group represented by formula (1-1) or (1-2) has a substitution degree of 0.05 to 0.20.4. The resin composition according to claim 3 ,wherein Y in formula (2) is a group selected from a hydrogen atom and a methyl group; and Z is a group selected from the group consisting of a hydrogen atom, a methyl group, a methoxycarbonyl group, an ethyl acetoacetate oxycarbonyl group, an acetyloxy group, a phenyl group, a cyano group and a pyrrolidonyl group.5. The resin composition according to claim 4 ,wherein Y in formula (2) is a group selected from a hydrogen atom and a methyl group; and Z is a group selected from the group consisting of a hydrogen atom, a cyano group, an ethyl acetoacetate oxycarbonyl group, and a methoxycarbonyl group.6. The resin composition according to claim 1 , containing at least one thermoplastic resin.7. The resin composition according to claim 6 ,wherein polymer compound residues in formulas (1-1) and (1-2) contain a component of the thermoplastic resin as a repeating unit.9. The resin composition according to claim 6 ,wherein the thermoplastic resin forms a continuous phase and the cellulose acetate ether compound forms a dispersed phase.10. The resin composition according to claim 1 ,wherein the stabilizer is a stabilizer of a phosphite compound or a hindered phenol compound.11. The resin composition according to claim 1 , containing at least one phosphorus compound flame retardant.12. The resin composition according to claim 1 , containing a fluorine-series resin.14. The resin composition according to claim 1 ,wherein the cellulose acetate ether compound is contained in a mass ratio of 10% or more and less than 50%, based on the total mass of the resin composition.16. A molded article formed of the cellulose acetate resin composition according to . The present invention ...

ESTERIFIED CELLULOSE ETHERS COMPRISING PHTHALYL GROUPS

An esterified cellulose ether is provided wherein the ester groups are phthalyl groups, the degree of substitution of phthalyl groups is from 0.02 to 0.18, the degree of neutralization of phthalyl groups is not more than 0.75, and the esterified cellulose ether has a solubility in water of at least 2.0 weight percent at 2° C. 1. A hydroxypropyl methyl cellulose phthalate , wherein{'sub': 6', '4', '6', '4', '6', '4, 'sup': −', '−, 'the degree of substitution of phthalyl groups is from 0.02 to 0.18, the degree of neutralization of phthalyl groups is not more than 0.75, wherein the degree of neutralization=[—C(O)—CH—COO]/[—C(O)—CH—COO+—C(O)—CH—COOH], and'}the hydroxypropyl methyl cellulose phthalate has a solubility in water of at least 2.0 weight percent at 2° C.2. The hydroxypropyl methyl cellulose phthalate of wherein the degree of substitution of phthalyl groups is from 0.05 to 0.17.3. The hydroxypropyl methyl cellulose phthalate of wherein the degree of neutralization of phthalyl groups is not more than 0.6.4. The hydroxypropyl methyl cellulose phthalate of wherein at least 85 wt % of the hydroxypropyl methyl cellulose phthalate is soluble in a mixture of 2.5 weight parts of the hydroxypropyl methyl cellulose phthalate and 97.5 weight parts of water at 2° C.5. A liquid composition comprising the hydroxypropyl methyl cellulose phthalate of dissolved in an aqueous liquid.6. The liquid composition of having a temperature of 15° C. or less.7. A liquid composition comprising at least one hydroxypropyl methyl cellulose phthalate of and an organic diluent.8. A process for coating a dosage form comprising the step of contacting the liquid composition of with the dosage form.9. A process for the manufacture of capsule shells comprising the step of contacting the liquid composition of with dipping pins.10. A coated dosage form wherein the coating comprises at least one hydroxypropyl methyl cellulose phthalate of .11. A polymeric capsule shell comprising at least one ...

Bulk material cover compositions and methods of applying

A cover material for a bulk material pile and method for applying the cover material are disclosed. The cover composition is free of fiber, clay, cement and pozzolanic material and comprises: 95 to 99.75 percent by weight water, 0.25 to 5 percent by weight of a water dispersible cellulosic polymer; and sufficient acid to maintain the pH of the solution between 1.0 and 6.0.

METHOD FOR PRODUCING NANOPARTICLES

The present invention describes a method for producing nanoparticles, wherein the nanoparticles contain or consist of hydroxypropyl methylcellulose acetate succinate (HPMCAS), and wherein i) HPMCAS is dissolved in an organic solvent in order to obtain an organic solution and ii) the organic solution is mixed with water to precipitate the nanoparticles in order to obtain precipitated nanoparticles and a mixed liquid phase as well as nanoparticles obtained by that method.

Composition for hot melt extrusion and method for producing hot melt extrudate by using same

Provided is a composition for hot melt extrusion including a drug and hypromellose acetate succinate (HPMCAS) having a hydroxypropoxy molar substitution of 0.40 or more and a mole ratio of an acetyl group to a succinyl group of less than 1.6. Further, provided is a method for producing a hot melt extrudate including the step of hot melt-extruding a composition for hot melt extrusion including a drug and hypromellose acetate succinate having a molar hydroxypropoxy substitution of 0.40 or more and a mole ratio of an acetyl group to a succinyl group of less than 1.6, at a hot melt temperature of not lower than a melting temperature of the hypromellose acetate succinate or of not lower than a temperature at which both the hypromellose acetate succinate and the drug are melted.

Process of preparing a high molecular weight esterified cellulose ether

An esterified cellulose ether of increased weight average molecular weight is produced in a process for reacting a cellulose ether with an aliphatic monocarboxylic acid anhydride and a dicarboxylic acid anhydride, wherein the process comprises the steps of a) preparing a reaction mixture comprising the cellulose ether, the dicarboxylic acid anhydride and a reaction diluent and heating the reaction mixture to a temperature of from 60 C to 110 C prior to, during or after mixing the components of the reaction mixture, and b) adding continuously or in at least three portions the monocarboxylic acid anhydride to the reaction mixture of step a) and completing the reaction.

Process for producing esterified cellulose ethers of very high molecular weight and low viscosity

A modified process for producing an esterified cellulose ether is provided which comprises the stages of i) preparing a reaction mixture comprising a cellulose ether, an aliphatic monocarboxylic acid anhydride, a dicarboxylic acid anhydride, and a reaction diluent and heating the reaction mixture to a temperature of from 60° C. to 110° C. prior to, during or after mixing the components of the reaction mixture to conduct an esterification reaction, and ii) before the esterification reaction is completed, adding an additional amount of reaction diluent continuously or in one or more portions to the reaction mixture and allowing the esterification reaction to further proceed.

NOVEL ESTERIFIED CELLULOSE ETHERS OF VERY HIGH MOLECULAR WEIGHT

Esterified cellulose ethers which comprise (i) groups of the formula —C(O)—R—COOA or (ii) a combination of aliphatic monovalent acyl groups and groups of the formula —C(O)—R—COOA, wherein R is a divalent aliphatic or aromatic hydrocarbon group and A is hydrogen or a cation, 1. A hydroxypropyl methyl cellulose acetate succinatehaving a DS(methoxyl) of from 1.6 to 2.05,having a viscosity of up to 50 mPa·s, measured as a 10 wt. % solution of the hydroxypropyl methyl cellulose acetate succinate in acetone at 20° C., and{'sub': 'w', 'having a weight average molecular weight Mof at least 220.000 Dalton,'}wherein the hydroxypropyl methyl cellulose acetate succinate has been produced by reacting a hydroxypropyl methyl cellulose having a DS(methoxyl) of from 1.6 to 2.05 with acetic anhydride and succinic anhydride in an aliphatic carboxylic acid as a reaction diluent at a molar ratio of aliphatic carboxylic acid to succinic anhydride of up to 12/1.2. The hydroxypropyl methyl cellulose acetate succinate of having a weight average molecular weight Mof at least 250 claim 1 ,000 Dalton.3. The hydroxypropyl methyl cellulose acetate succinate of having a viscosity of up 40 mPa·s claim 1 , measured as a 10 wt. % solution of the hydroxypropyl methyl cellulose acetate succinate in acetone at 20° C.4. The hydroxypropyl methyl cellulose acetate succinate of having a DS(methoxyl) of from 1.7 to 2.05.5. A composition comprising a liquid diluent and at least one hydroxypropyl methyl cellulose acetate succinate of .6. The composition of comprising from 5 to 20 percent of at least one hydroxypropyl methyl cellulose acetate succinate claim 5 , from 65 to 94 percent of a liquid diluent claim 5 , and from 1 to 15 percent of an active ingredient claim 5 , based on the total weight of the composition.7. A solid dispersion comprising at least one active ingredient and at least one hydroxypropyl methyl cellulose acetate succinate of .8. A dosage form being coated with at least one hydroxypropyl ...

Pharmaceutical Compositions With Enhanced Performance and Improved Processability

The presently disclosed and claimed inventive concept(s) relates to a polymer for enhancing drug performance and improving processability. Specifically, the polymer comprises hydroxypropyl methyl cellulose acetate succinate (HPMC-AS). On the HPMC-AS, the percentage of total succinoyl degree of substitution is less than 12% at C6-OH position and greater than 53% at C3-OH, and the percentage of total acetyl degree of substitution is greater than 32% at C6-OH position.

DISPERSION COMPRISING AN ESTERIFIED CELLULOSE ETHER

An aqueous composition useful for producing capsules shells comprises a) at least one dispersed esterified cellulose ether comprising (i) groups of the formula —C(O)—R—COOA or (ii) a combination of aliphatic monovalent acyl groups and groups of the formula —C(O)—R—COOA, wherein R is a divalent aliphatic or aromatic hydrocarbon group and A is hydrogen or a cation, and b) from 0.05 to 20 percent of at least one salt of a fatty acid, based on the weight of the dispersed esterified cellulose ether, wherein the median particle size, d50, of the dispersed esterified cellulose ether particles is up to 7 micrometers, such median particle size (d50) being the size at which 50 mass percent of the particles have a smaller equivalent diameter and 50 mass percent have a larger equivalent diameter. 1. An aqueous composition comprisinga) at least one dispersed esterified cellulose ether comprising (i) groups of the formula —C(O)—R—COOA or (ii) a combination of aliphatic monovalent acyl groups and groups of the formula —C(O)—R—COOA, wherein R is a divalent aliphatic or aromatic hydrocarbon group and A is hydrogen or a cation, andb) from 0.05 to 20 percent of at least one salt of a fatty acid, based on the weight of the dispersed esterified cellulose ether,wherein the median particle size, d50, of the dispersed esterified cellulose ether particles is up to 5 micrometers, such median particle size (d50) being the size at which 50 mass percent of the particles have a smaller equivalent diameter and 50 mass percent have a larger equivalent diameter.2. The aqueous composition of comprising from 0.5 to 10 percent of an ammonium claim 1 , alkali metal or alkaline earth metal salt of a saturated or unsaturated fatty acid claim 1 , based on the weight of the dispersed esterified cellulose ether.3. The aqueous composition of wherein the salt of a fatty acid is an ammonium claim 1 , alkali metal or alkaline earth metal salt of stearic acid or oleic acid.4. The aqueous composition of ...

CELLULOSE ETHER ACETATE PHTHALATES

A cellulose ether acetate phthalate is provided, wherein the degree of substitution of phthalyl groups is from 0.02 to 0.25, the degree of neutralization of phthalyl groups is not more than 0.5, the degree of substitution of acetyl groups is from 0.02 to 0.40, and the total degree of substitution of phthalyl and acetyl groups is not more than 0.50. The cellulose ether acetate phthalate has a solubility in water of at least 2.0 weight percent at 2° C. 1. A hydroxypropyl methyl cellulose acetate phthalate wherein{'sub': 6', '4', '6', '4', '6', '4, 'sup': −', '−, 'the degree of substitution of phthalyl groups is from 0.02 to 0.25, the degree of neutralization of phthalyl groups is not more than 0.5, wherein the degree of neutralization=[—C(O)—CH—COO]/[—C(O)—CH—COO+—C(O)—CH—COOH], and'}the degree of substitution of acetyl groups is from 0.07 to 0.25.2. The hydroxypropyl methyl cellulose acetate phthalate of having a solubility in water of at least 2.0 weight percent at 2° C.3. The hydroxypropyl methyl cellulose acetate phthalate of wherein the degree of substitution of phthalyl groups is from 0.04 to 0.15.4. The hydroxypropyl methyl cellulose acetate phthalate of wherein at least 85 wt. % of the hydroxypropyl methyl cellulose acetate phthalate is soluble in a mixture of 2.5 weight parts of the hydroxypropyl methyl cellulose acetate phthalate and 97.5 weight parts of water at 2° C.5. A liquid composition comprising at least one hydroxypropyl methyl cellulose acetate phthalate of dissolved in an aqueous liquid.6. The liquid composition of having a temperature of less than 15° C.7. A liquid composition comprising at least one hydroxypropyl methyl cellulose acetate phthalate of and an organic diluent.8. A process for coating a dosage form comprising the step of contacting the liquid composition of with the dosage form.9. A process for the manufacture of capsule shells comprising the step of contacting the liquid composition of with dipping pins.10. A coated dosage form ...

Acetylated cellulose ether, method for preparing same, and article comprising the acetylated cellulose ether

Disclosed are acetylated cellulose ether, a method of preparing the same, and an article including the same. The disclosed acetylated cellulose ether has a degree of substitution (DS) of alkyl group of 1 to 2, a molar substitution (MS) of hydroxyalkyl group of 0 to 1, and a degree of substitution (DS) of acetyl group of 1 to 2; and a bulk density of 0.1 to 0.4.

WATER-REDISPERSIBLE POLYMER POWDER

In a water-redispersible polymer powder—the polymer is at least one esterified cellulose ether comprising (i) groups of the formula —C(O)—R—COOA or (ii) a combination of aliphatic monovalent acyl groups and groups of the formula —C(O)—R—COOA, wherein R is a divalent aliphatic or aromatic hydrocarbon group and A is hydrogen or a cation, and—the polymer powder comprises from 0.05 to 20 percent of at least one salt of a fatty acid, based on the weight of the esterified cellulose ether(s). 1. A water-redispersible polymer powder , whereinthe polymer is at least one esterified cellulose ether comprising (i) groups of the formula —C(O)—R—COOA or (ii) a combination of aliphatic monovalent acyl groups and groups of the formula —C(O)—R—COOA, wherein R is a divalent aliphatic or aromatic hydrocarbon group and A is hydrogen or a cation, andthe polymer powder comprises from 0.05 to 20 percent of at least one salt of a fatty acid, based on the weight of the esterified cellulose ether(s).2. The water-redispersible polymer powder of comprising from 0.5 to 10 percent of an ammonium claim 1 , alkali metal or alkaline earth metal salt of a saturated or unsaturated fatty acid claim 1 , based on the weight of the esterified cellulose ether.3. The water-redispersible polymer powder of wherein the salt of a fatty acid is an ammonium claim 1 , alkali metal or alkaline earth metal salt of stearic acid or oleic acid.4. The water-redispersible polymer powder of wherein the degree of neutralization of the groups —C(O)—R—COOA is not more than 0.4.5. The water-redispersible polymer powder of wherein the aliphatic monovalent acyl groups in the esterified cellulose ether are acetyl claim 1 , propionyl or butyryl groups claim 1 , and the groups of the formula —C(O)—R—COOA are —C(O)—CH—CH—COOA claim 1 , —C(O)—CH═CH—COOA claim 1 , or —C(O)—CH—COOA groups.6. The water-redispersible polymer powder of wherein the esterified cellulose ether is hydroxypropyl methyl cellulose acetate succinate.7. The ...

INJECTION MOLDING COMPOSITION CONTAINING HYPROMELLOSE ACETATE SUCCINATE AND METHOD FOR PRODUCING SAME

An injection molding composition is capable of being injection-molded easily at a temperature lower than that of a conventional composition, and an injection molded product has improved strength. More specifically, an injection molding composition containing HPMCAS has a hydroxypropoxy molar substitution of 0.40 or more. In addition, a method produces an injection molded product including a step of injecting into a mold the injection molding composition at from 50 to 250° C. 1. An injection molding composition comprising hypromellose acetate succinate having a hydroxypropoxy molar substitution of 0.40 or more.2. The injection molding composition according to claim 1 , wherein the hypromellose acetate succinate has a glass transition temperature (Tg) of 110° C. or less.3. A method for producing an injection molded product claim 1 , comprising a step of injecting into a mold the injection molding composition as claimed in at from 50 to 250° C.4. The method for producing an injection molded product according to wherein the injection molded product is a hard capsule.5. A method for producing an injection molded product claim 2 , comprising a step of injecting into a mold the injection molding composition as claimed in at from 50 to 250° C.6. The method for producing an injection molded product according to wherein the injection molded product is a hard capsule. The present invention relates to an injection-molded product using a hypromellose acetate succinate and a method for producing the injection-molded product.Injection molding is one of the methods for producing a pharmaceutical solid preparation such as a hard capsule. This method is advantageous because it does not require a solvent so that energy in the drying step can be reduced.For such a pharmaceutical solid preparation, a pharmaceutically acceptable, for example, an orally administrable polymer is generally used. As one example of the polymer, there is a hypromellose acetate succinate (which may hereinafter ...

Hair Fixatives Including Starch Ester Based Polyglucose Polymers

A hair fixative composition includes at least one carboxylated starch ester based polyglucose polymer, an alcohol based solvent system, and a cosmetically acceptable additive, wherein the polyglucose polymer is soluble in the alcohol based solvent system. The polyglucose polymer is obtained by reacting at least one starch ester with at least one cyclic anhydride.

METHODS AND COMPOSITIONS FOR WEIGHT MANAGEMENT AND FOR IMPROVING GLYCEMIC CONTROL

The present invention provides methods, compositions and modified foods and foodstuffs useful for weight management and glycemic control. 1. A modified food or foodstuff comprising an edible polymer hydrogel.248-. (canceled)49. A method of enhancing glycemic control in a subject in need thereof , comprising the step of orally administering to the subject an effective amount of an edible polymer hydrogel wherein said edible polymer hydrogel swells in the subject's stomach , the subject's small intestine or both.50. The method of claim 49 , wherein the edible polymer hydrogel is administered to the subject with food or up to two hours prior to eating.51. The method of claim 49 , wherein the edible polymer hydrogel has a swelling ratio of more than 40.52. The method of claim 49 , wherein the edible polymer hydrogel has an elastic modulus of at least 200 Pa.53. The method of claim 49 , wherein the edible polymer hydrogel has a viscosity of at least 15 s.54. The method of claim 49 , wherein the edible polymer hydrogel swells in both the stomach and small intestine of the subject.55. The method of claim 49 , wherein the edible polymer hydrogel swells in the subject's small intestine but not in the subject's stomach.56. The method of claim 55 , wherein the edible polymer hydrogel is administered with an enteric coating.57. The method of claim 49 , wherein the subject is obese claim 49 , overweight or normal weight.58. The method of claim 49 , wherein the edible polymer hydrogel is administered in an amount sufficient to increase the viscosity and elastic modulus of the gastrointestinal content and slow gastric emptying and absorption of carbohydrates and fats in the subject's small intestine.59. The method of claim 49 , wherein the polymer gel comprises a hydrophilic polymer cross-linked with a polycarboxylic acid.60. The method of claim 59 , wherein the hydrophilic polymer is an anionic polymer.61. The method of claim 60 , wherein the anionic polymer is ...

Processes for making cellulose ester compositions

A cellulose ester composition is provided comprising at least one cellulose ester and at least one additive selected from the group consisting of a compatibilizer, and a plasticizer. Processes for producing the cellulose ester composition are also provided. In another embodiment, a cellulose ester/elastomer composition is provided comprising at least one elastomer, at least one cellulose ester; and at least one additive; wherein the additive is at least one selected from the group consisting of a compatibilizer and a plasticizer. Processes for producing the cellulose ester/elastomer composition is also provided as well as articles comprising the cellulose ester/elastomer composition.

Poly(hydroxy ether) polymers blended with cyclic ester polymers

WHEREIN EACH R, individually, is selected from the class consisting of hydrogen, alkyl, halo, and alkoxy; A is the oxy group; x is an integer from 1 to 4; y is an integer from 1 to 4; z is an integar of zero or one; with the provisos that (a) the sum of x + y + z is at least 4 and not greater than 7, and (b) the total number of R variables which are substituents other than hydrogen does not exceed 3, with or without recurring units of the formula (II) wherein each R'' is selected from the class consisting of, individually, hydrogen, alkyl, cycloalkyl, aryl, and chloroalkyl, and, together with the ethylene moiety of the oxyethylene chain of Unit II, a saturated cycloaliphatic hydrocarbon ring having from 4 to 8 carbon atoms; and thermoplastic, normally solid polymer which can be a condensation polymer, and/or an addition polymer of olefinically unsaturated monomers having no more than one hydrogen bonded to each carbon of each olefinically unsaturated group thereof, including such polymers as cellulose derivatives, nylons, polyester polymers, polyoxyalkylenes, polycarbonates, poly(fluorocarbons), coumarone-indene resins, maleic acid or anhydride addition polymers and copolymers, stilbene addition polymers and copolymers, chlorinated polyethers, aromatic poly(hydroxy ether) polymers, polysufones, polypeptides, etc. These novel blends are useful in the production of fibers, films, coatings, adhesives, wire and cable coatings, molding materials, extrusion materials, or shaped articles, having one or more unique properties, such as, dyeability, improved stress crack resistance, improved optical properties, e.g., improved hiding power, low haze, high gloss and/or high light transmission, improved plasticization, improved toughness, improved melt processability, improved impact resistance, and/or improved ability to disperse additives, such as, fillers coloring agents, antioxidants, extenders, etc. Uniform, thermoplastic, normally solid blends containing cyclic ...

Methods and compositions for weight management and for improving glycemic control

초고분자량의 신규한 에스테르화된 셀룰로스 에테르

에스테르화된 셀룰로스 에테르로서, (i) 화학식 -C(O)-R-COOA의 그룹 또는 (ii) 지방족 1가 아실 그룹과 화학식 -C(O)-R-COOA의 그룹의 배합물을 포함하고, 여기서 R은 2가 지방족 또는 방향족 탄화수소 그룹이고, A는 수소 또는 양이온이며, 20℃에서 아세톤 중의 상기 에스테르화된 셀룰로스 에테르의 10중량% 용액으로서 측정된 바 50mPaㆍs 이하의 점도를 갖고 220,000달턴 이상의 중량 평균 분자량 M w 를 갖거나; 20℃에서 아세톤 중의 상기 에스테르화된 셀룰로스 에테르의 10중량% 용액으로서 측정된 바 100mPaㆍs 이하의 점도를 갖고 310,000달턴 이상의 중량 평균 분자량 M w 를 갖는 에스테르화된 셀룰로스 에테르는, 약물을 포함하는 고체 분산체의 제조에 유용하다.

Low molecular weight carboxyalkylcellulose esters and their use as low viscosity binders and modifiers in coating compositions

Carboxyalkylcellulose esters are disclosed having relatively low degrees of polymerization. These new carboxyalkylcellulose esters include carboxymethylcellulose acetate, carboxymethylcellulose acetate propionate, and carboxymethylcellulose acetate butyrate. The inventive esters exhibit solubility in a range of organic solvents, and are useful in coatings and ink compositions as binder resins and rheology modifiers.

Cellulose esters or ethers blended with cyclic ester polymers

Uniform, thermoplastic, normally solid blends containing cyclic ester polymers containing recurring units of the formula WHEREIN EACH R, individually, is selected from the class consisting of hydrogen, alkyl, halo, and alkoxy; A is the oxy group; x is an integer from 1 to 4; y is an integer from 1 to 4; z is an integer of zero or one; with the provisos that (a) the sum of x + y + z is at least 4 and not greater than 7, and (b) the total number of R variables which are substituents other than hydrogen does not exceed 3, with or without recurring units of the formula wherein each R'' is selected from the class consisting of, individually, hydrogen, alkyl, cyclcoalkyl, aryl, and chloroalkyl, and, together with the ethylene moiety of the oxyethylene chain of Unit II, a saturated cycloaliphatic hydrocarbon ring having from 4 to 8 carbon atoms; and thermoplastic normally solid polymer which can be a condensation polymer, and/or an addition polymer of olefinically unsaturated monomers having no more than one hydrogen bonded to each carbon of each olefinically unsaturated group thereof, including such polymers as cellulose derivatives, nylons, polyester polymers, polyoxyalkylenes, polycarbonates, poly(fluorocarbons), coumaroneindene resins, maleic acid or anhydride addition polymers and copolymers, stilbene addition polymers and copolymers, chlorinated polyethers, aromatic poly(hydroxy ether) polymers, polysufones, polypeptides, etc. These novel blends are useful in the production of fibers, films, coatings, adhesives, wire and cable coatings, molding materials, extrusion materials, or shaped articles, having one or more unique properties, such as, dyeability, improved stress crack resistance, improved optical properties, e.g., improved hiding power, low haze, high gloss and/or high light transmission, improved plasticization, improved toughness, improved melt processability, improved impact resistance, and/or improved ability to disperse additives, such as, fillers ...

Polysaccharide based cement additives

A composition comprising a carboxylated, sulfonated polysaccharide and a wellbore servicing fluid. A wellbore servicing composition comprising a hydraulic cement and a carboxylated, sulfonated polysaccharide. A wellbore servicing composition comprising a polysaccharide having carboxylate and sulfonate groups.

Polysaccharide based cement additives

A composition comprising a carboxylated, sulfonated polysaccharide and a wellbore servicing fluid. A wellbore servicing composition comprising a hydraulic cement and a carboxylated, sulfonated polysaccharide. A wellbore servicing composition comprising a polysaccharide having carboxylate and sulfonate groups.

Biodegradable blends and films having nano-structural features

A thermoplastic polymer composition with a tertiary blend of a carbon dioxide-derived polymer, a thermoplastic cellulose derivative, and a thermoplastic compatibilizer is described. The composition can be melt-processed into flexible, thin films that have fine nano-scale structural features in both the cross-directional and machine-directional orientations, for use in various products. The films, which are made from relatively brittle materials, exhibit a greater degree of ductility, elongation capacity, and strength than the primary, original component materials as binary-blends from which the film is made.

The water-soluble esterified cellulose ether

1. i) R이 2가 탄화수소 기인, 식 - C(O) - R - COOH의 기 또는 지방족 1가 아실 기와 식 -C(O) - R - COOH의 기의 조합을 포함하고, ii) 최대 70,000 달톤의 중량 평균 분자량 M w 를 갖고, iii) 0.4 이하의 - C(O) - R - COOH 기의 중화도를 갖고, 그리고 iv) 2℃에서 적어도 2.0 중량 퍼센트의 물에서 용해도를 가지며, 장용성 캡슐을 제조하는데 유용한 에스테르화된 셀룰로오스 에테르.

Cellulose composite

Pharmaceutical compositions with enhanced performance and improved processability

본원에 개시되고 청구된 발명의 개념(들)은 약물 성능을 증진시키고 가공성을 개선시키기 위한 중합체에 관한 것이다. 구체적으로, 상기 중합체는 히드록시프로필 메틸 셀룰로스 아세테이트 숙시네이트 (HPMC-AS)를 포함한다. HPMC-AS 상에서, 숙시노일의 총 치환도의 백분율은 C6-OH 위치에서 12% 미만이고 C3-OH에서 53% 초과이고, 아세틸의 총 치환도의 백분율은 C6-OH 위치에서 32% 초과이다.

Usage of carboxymethyl cellulose acetate butyrate

一种用于改善在涂层纤维素基材(例如人造纤维板)上的固着性的方法。所述方法包括以下步骤：将含水的羧甲基纤维素乙酸酯丁酸酯胶料组合物施用到人造纤维基材上，形成施胶的基材。然后干燥施胶的基材。接下来，施用含水的涂料组合物，形成涂层的施胶基材。然后干燥涂层的施胶基材。根据本发明，用于所述方法的含水羧甲基纤维素乙酸酯丁酸酯胶料组合物含有羧甲基纤维素乙酸酯丁酸酯、水和有机溶剂。本发明也涉及一种施胶的人造纤维基材，其含有人造纤维基材和羧甲基纤维素乙酸酯丁酸酯胶料。所述羧甲基纤维素乙酸酯丁酸酯可以是内施胶剂或者外施胶剂。

Aqueous dispersions utilizing carboxyalkyl cellulose esters and water reducible polymers

Aqueous dispersions containing hydrophobic materials that are useful as reduced volatile organic content may be utilized as a coating, a stain, a resin, a polymer, or an additive. Specifically, the aqueous dispersion may contain one or more of a carboxyalkyl cellulose ester, such as carboxymethyl cellulose acetate butyrate, a fluorosurfactant, such as a polyoxetane fluorosurfactant or a fluoroaliphatic polymeric ester based surfactant, a water dispersible resin, and optionally, a C-11 ketone and/or surfactant.

Water-redispersible polymer powder

In a water-redispersible polymer powder - the polymer is at least one esterified cellulose ether comprising (i) groups of the formula -C(O) - R - COOA or (ii) a combination of aliphatic monovalent acyl groups and groups of the formula -C(O) - R - COOA, wherein R is a divalent aliphatic or aromatic hydrocarbon group and A is hydrogen or a cation, and - the polymer powder comprises from 0.05 to 20 percent of at least one salt of a fatty acid, based on the weight of the esterified cellulose ether(s).

Aqueous composition comprising dispersed esterified cellulose ether

An aqueous composition which is useful for producing coatings and capsule shells comprises a) dispersed particles of an esterified cellulose ether comprising (i) groups of the formula —C(O)—R—COOA or (ii) a combination of aliphatic monovalent acyl groups and groups of the formula —C(O)—R—COOA, wherein R is a divalent hydrocarbon group and A is hydrogen or a cation, and the total degree of ester substitution is more than 0.70, and b) an esterified cellulose ether comprising aliphatic monovalent acyl groups and groups of the formula —C(O)—R—COOH, R being a divalent hydrocarbon group, wherein I) the degree of neutralization of the groups —C(O)—R—COOH is not more than 0.4, II) the total degree of ester substitution is from 0.03 to 0.70, and III) the esterified cellulose ether b) has a solubility in water of at least 2.0 weight percent at 2° C.

Pharmaceutical composition having enhanced performance and improved processability

Methods and compositions for weight management and blood glucose management

Lithium-surfur cell adhesive and positive active substance copmosition comprising same and lithium-surfur cell using same

本发明公开了一种用于锂硫电池的包括丁二烯基共聚物的粘合剂。该粘合剂具有化学耐多硫化物性，在电池的工作温度下稳定，在有机溶剂中形成乳剂，并对锂硫电池中使用的正极活性物质和电极具有高的粘附性。由于对正极活性物质具有高的粘附性，所公开的粘合剂组合物使得用于电池的正极活性物质具有较高的相对量，从而得到高容量的锂硫电池。

MOLDING MATERIAL, MOLDED BODY, MANUFACTURING METHOD THEREOF, AND CASE FOR ELECTRIC AND ELECTRONIC DEVICE

Acetylated cellulose ether and articles comprising the same

아세틸화 셀룰로오스 에테르 및 이를 포함하는 물품이 개시된다. 개시된 아세틸화 셀룰로오스 에테르는, 1~2의 알킬기 치환도(DS), 0~1의 히드록시알킬기 치환도(MS) 및 1~2의 아세틸기 치환도(DS)를 갖는다.

Cellulose derivative and process for production thereof, cellulose resin composition, molded article and method for production thereof, and housing for electrochemical device

Disclosed is a cellulose derivative having good thermal plasticity, strength and heat resistance and suitable for molding. In the cellulose derivative, at least a part of hydrogen atoms in hydroxy groups contained in the cellulose moiety is substituted by a hydrocarbon group having 1 to 7 carbon atoms and an aliphatic acyl group having 4 to 11 carbon atoms.

Cellulose derivative, thermoforming material, molded body, method for producing the same, and casing for electric and electronic equipment

Pharmaceutical compositions with enhanced performance comprising a hpmca polymer

Disclosed are polymers of hydroxypropyl methyl cellulose acetate succinate (HPMCAS) and hydroxypropyl methyl cellulose acetate (HPMCA) with unique degrees of substitution of hydroxypropoxy, methoxy, acetyl, and succinoyl groups. When used in making compositions comprising a low-solubility drug and such polymers, the polymers provide enhanced aqueous concentrations and/or improved physical stability.

The pharmaceutical composition of performance and improved processability with enhancing

本文公开和要求保护的发明构思涉及用于增强药物性能和改善加工性的聚合物。具体地，所述聚合物包含醋酸羟丙基甲基纤维素琥珀酸酯(HPMC‑AS)。在所述HPMC‑AS上，琥珀酰基总取代度的百分比在C6‑OH位置小于12％并且在C3‑OH位置大于53％，并且乙酰基总取代度的百分比在C6‑OH位置大于32％。

esterified cellulose ether, composition, solid dispersion, dosage form and capsule shell

resumo “éter de celulose esterificado, composição, dispersão sólida, forma de dosagem e invólucro de cápsula” éteres de celulose esterificados compreendendo (i) grupos da fórmula –c(o)-r-cooa ou (ii) uma combinação de grupos acila alifáticos monovalentes e grupos da fórmula –c(o)-r-cooa, onde r é um grupo hidrocarboneto alifático ou aromático divalente e a é hidrogênio ou um cátion, que tem uma viscosidade de até 50 mpa.s, medida como uma solução de 10% em peso do éter de celulose esterificado em acetona a 20ºc, e um peso molecular médio ponderal mw de pelo menos 220.000 daltons e uma viscosidade de até 100 mpa.s, medida como solução de 10% em peso do éter de celulose esterificado em acetona a 20ºc, e um peso molecular médio ponderal mw de pelo menos 310.000 daltons são úteis no preparo de fármacos compreendendo dispersões sólidas. "esterified cellulose ether, composition, solid dispersion, dosage form and capsule shell" esterified cellulose ethers comprising (i) groups of the formula -c (o) -r-cooa or (ii) a combination of aliphatic acyl groups monovalent groups and groups of the formula -c (o) -r-cooa, where r is a divalent aliphatic or aromatic hydrocarbon group and a is hydrogen or a cation, which has a viscosity of up to 50 mpa.s, measured as a solution of 10 % by weight of acetone esterified cellulose ether at 20 ° C, and a weight average molecular weight mw of at least 220,000 daltons and a viscosity of up to 100 mpa.s measured as a 10% by weight solution of acetone esterified cellulose ether at 20 ° C, and a weight average molecular weight mw of at least 310,000 daltons are useful in the preparation of drugs comprising solid dispersions.

Dispersion comprising an esterified cellulose ether

하기를 포함하는 캡슐 쉘 제조에 유용한 수성 조성물: a) (i) 화학식 -C(O)-R-COOA의 기 또는 (ii) 지방족 1가 아실기와 화학식 -C(O)-R-COOA(식 중, R은 2가 지방족 또는 방향족 탄화수소기이고, A는 수소 또는 양이온이다)의 조합을 포함하는 적어도 1종의 분산 에스테르화된 셀룰로오스 에테르, 및 b) 상기 분산 에스테르화된 셀룰로오스 에테르의 중량을 기준으로 하여, 0.05 내지 20%의 적어도 1종의 지방산의 염(여기에서 상기 분산 에스테르화된 셀룰로오스 에테르 입자의 중위 입자 크기(d50)는 최대 7 마이크로미터이고, 상기 중위 입자 크기(d50)는 상기 입자의 50 질량%가 소형 등가 직경을 갖고 50 질량%가 대형 등가 직경을 갖는 크기이다) Aqueous compositions useful for preparing capsule shells comprising: a) (i) a group of the formula -C(O)-R-COOA or (ii) an aliphatic monovalent acyl group with the formula -C(O)-R-COOA wherein R is a divalent aliphatic or aromatic hydrocarbon group, and A is hydrogen or a cation) at least one dispersion esterified cellulose ether, and b) based on the weight of the dispersion esterified cellulose ether wherein 0.05 to 20% of a salt of at least one fatty acid, wherein the median particle size (d50) of the dispersed esterified cellulose ether particles is at most 7 micrometers, and the median particle size (d50) is the particle size 50% by mass of has a small equivalent diameter and 50% by mass has a large equivalent diameter)

Hydroxypropyl methylcellulose phthalate particles and their production method

Soluble ester cellulose ether with low degree of neutralization

一种包含脂肪族单价酰基和式‑C(O)‑R‑COOH的基团的酯化纤维素醚，R是二价烃基，所述酯化纤维素醚具有以下性质：i)所述基团‑C(O)‑R‑COOH的中和度不大于0.4，ii)总酯取代度是0.10到0.70，以及iii)所述酯化纤维素醚在2C下在水中的溶解度是至少2.0重量％。

Positive active material composition for lithium sulfur battery and lithium sulfur battery fabricated using binder

본 발명은 리튬 황 전지용 바인더에 관한 것으로서, 이 바인더는 아크릴로니트릴 함유 공중합체를 포함한다. The present invention relates to a binder for a lithium sulfur battery, the binder comprising an acrylonitrile-containing copolymer. 본 발명의 바인더는 결착력이 매우 우수하여, 그 사용량을 줄일수 있으므로, 많은 양극 활물질을 사용할 수 있어, 고용량 리튬 황 전지를 제공할 수 있다. Since the binder of the present invention has excellent binding power and can reduce the amount of use thereof, many positive electrode active materials can be used, thereby providing a high capacity lithium sulfur battery.

Optical film, circularly polarizing plate and organic electroluminescent display device

Provided is an optical film containing a cellulose derivative, the optical film having an in-plane retardation Ro 550 within the range of 120 to 160 nm measured at a wavelength of 550 nm under an atmosphere of a temperature of 23° C. and a relative humidity of 55%, and a ratio Ro 450 /Ro 550 within the range of 0.65 to 0.99, Ro 450 /Ro 550 being a ratio of an in-plane retardation Ro 450 measured at a wavelength of 450 nm to the in-plane retardation Ro 550 measured at a wavelength of 550 nm, wherein, a substituent of a glucose skeleton in the cellulose derivative satisfies the requirements (a) and (b) which are described in the specification, and the optical film contains a compound A satisfying the following condition defined by Expression (a1) which is described in the specification.

Biodegradable blends and films having nano-structural features

本发明描述了一种具有二氧化碳衍生的聚合物、热塑性纤维素衍生物和热塑性增容剂的三元共混物的热塑性聚合物组合物。所述组合物可熔融加工为在横向和纵向上均具有细密的纳米级结构特征的柔韧性薄膜。该膜由相对较脆的材料制得，与用于制备膜的作为二元共混物的主要的、原始的组分材料相比，显示更大程度的延展性、伸长能力和强度。

HPMCAS and its production method and the composition containing it

提供一种乙酸琥珀酸羟丙甲纤维素(HPMCAS)，其显示高的溶解度并且当溶解在溶剂中时能够抑制未溶解材料的生成；提供一种含有HPMCAS的组合物；以及提供用于生产该HPMCAS的方法。更具体地，提供一种HPMCAS，其具有2位MS与3位MS的1.2或更小的比率，其中2位MS意指已将在HPMCAS的每个葡萄糖单元的2位碳上的羟基基团的氢原子直接代替的羟丙基基团的摩尔取代度，并且3位MS意指已将在HPMCAS的每个葡萄糖单元的3位碳上的羟基基团的氢原子直接代替的羟丙基基团的摩尔取代度；提供一种包含该HPMCAS以及溶剂的组合物；以及用于生产该HPMCAS的方法。

Hydroxypropyl methyl cellulose phthalate, method for producing the same, and composition for hot-melt extrusion

[과제] 세정 회수 공정에 제공되는 반응 혼합물 중의 아세트산을 저감시킬 수 있고, 유동성이 우수한 히드록시프로필메틸셀룰로오스프탈레이트(HPMCP)를 효율적으로 제조한다. [해결수단] 용매로서 아세트산을 사용하고, 히드록시프로필메틸셀룰로오스(HPMC)와 무수 프탈산의 에스테르화 반응을 행함으로써, HPMCP를 함유하는 반응 용액을 얻는 에스테르화 반응 공정과, 상기 반응 용액에 물을 가함으로써, 물 첨가 반응 용액을 얻는 물 첨가 공정과, 상기 물 첨가 반응 용액으로부터 상기 아세트산의 적어도 일부를 제거함으로써, 상기 아세트산의 함유량이 저감된 혼합물을 얻는 아세트산 제거 공정과, 상기 혼합물을 세정하여 상기 HPMCP를 회수하는 세정 회수 공정을 적어도 포함하는 HPMCP의 제조 방법 등을 제공한다.

Biopolymer compositions and products thereof

This invention relates to biopolymer-based compositions and biopolymer-based formed bodies such as film, sheet, capsule, casing or coating-film or spray thereof. In another embodiment, the invention relates to a process for producing a biopolymer-based starting material and biopolymer-based formed bodies such as cited above, for the manufacture of pharmaceutical, veterinary, food for cosmetic products.

Water-soluble esterified cellulose ethers having a low degree of neutralization

An esterified cellulose ether comprising aliphatic monovalent acyl groups and groups of the formula - C(O) - R - COOH, R being a divalent hydrocarbon group, has the following properties: i) the degree of neutralization of the groups - C(O) - R - COOH is not more than 0.4, ii) the total degree of ester substitution is from 0.10 to 0.70, and iii) the esterified cellulose ether has a solubility in water of at least 2.0 weight percent at 2 C.

Low molecular weight cellulose mixed esters and their use as low viscosity binders and modifiers in coating compositions

Cellulose mixed esters are disclosed having low molecular weights and low degrees of polymerization. These new cellulose mixed esters include cellulose acetate propionate and cellulose acetate butyrate. The esters exhibit solubility in a wide range of organic solvents with minimal viscosity increase, are compatible with a wide variety of resins, and are useful in coatings and inks compositions as binder resins and rheology modifiers.

Efficient process for preparing an ester of a cellulose ether

A process for producing an esterified cellulose ether can be efficiently be produced by reacting a moist cellulose ether having a water content of at least 10 percent, based on the weight of the moist cellulose ether, with an aliphatic monocarboxylic acid anhydride, a dicarboxylic acid anhydride or a combination thereof. Further improvements in efficiency and reduction in process steps are achieved in a process for producing an esterified cellulose ether which comprises the steps of a) reacting cellulose with an alkaline material to produce alkali cellulose, b) reacting the produced alkali cellulose with one or more etherifying agents and washing the produced cellulose ether to obtain a moist cellulose ether having a water content of at least 10 weight percent, and c) reacting the moist cellulose ether with an aliphatic monocarboxylic acid anhydride and/or a dicarboxylic acid anhydride and with a depolymerizing agent.

Cross-linkable polymer dispersions, method for the production thereof and use thereof

The invention relates to compositions comprising an aqueous dispersion of selected polymers and selected polyaldehydes as cross-linking agents. Said formulations may be used to produce adhesives with a very high resistance to boiling water.

Low-substituted hydroxypropyl cellulose, production method thereof, and solid preparation

양호한 결합성 및 캐핑 방지 성능을 갖는 저치환도 히드록시프로필 셀룰로오스를 제공한다. 구체적으로는, 히드록시프로폭시기 함유량이 5 내지 16질량％이며, 동적 화상 해석법에 의해 전체 입자를 미립자와, 구상 입자와, 장섬유상 입자 및 단섬유상 입자로 이루어지는 섬유상 입자로 분류한 경우, 상기 장섬유상 입자의 체적 분율이 15 내지 50％이며, 상기 단섬유상 입자의 체적 분율이 23 내지 60％인 저치환도 히드록시프로필 셀룰로오스, 및 이 저치환도 히드록시프로필 셀룰로오스를 포함하는 고형 제제를 제공한다. 또한, 길이 평균 섬유 길이가 2.40 내지 3.50mm인 시트상 펄프 또는 칩상 펄프와, 알칼리 금속 수산화물 용액을 접촉시켜 알칼리 셀룰로오스를 얻는 공정과, 상기 알칼리 셀룰로오스와 산화프로필렌을 반응시켜 반응 생성물을 얻는 공정과, 상기 반응 생성물을, 적어도 산을 포함하는 수중에 분산시켜 일부 용해시킨 후, 산으로 중화하여 조 저치환도 히드록시프로필 셀룰로오스를 석출시키는 공정 등을 포함하는 상기 저치환도 히드록시프로필 셀룰로오스의 제조 방법을 제공한다. A low-substituted hydroxypropyl cellulose having good bonding properties and anti-capping performance is provided. Specifically, when the hydroxypropoxyl group content is 5 to 16% by mass, and all the particles are classified into fine particles, spherical particles, and fibrous particles composed of long fibrous particles and short fibrous particles by a dynamic image analysis method, the above Low-substituted hydroxypropyl cellulose having a volume fraction of long fibrous particles of 15 to 50% and a volume fraction of short fibrous particles of 23 to 60%, and a solid preparation containing the low-substituted hydroxypropyl cellulose do. Further, a step of contacting sheet-like pulp or chip-like pulp having a length average fiber length of 2.40 to 3.50 mm with an alkali metal hydroxide solution to obtain alkali cellulose, and a step of reacting the alkali cellulose with propylene oxide to obtain a reaction product; A process for producing the low-substituted hydroxypropyl cellulose comprising a step of dispersing the reaction product in water containing at least an acid to partially dissolve it, and then neutralizing the reaction product with an acid to precipitate crude low-substituted hydroxypropyl cellulose. provides

Water-soluble esterified cellulose ethers having a low degree of neutralization

RESUMEN DE LA INVENCIÓN La presente invención se refiere a un éter de celulosa esterificado que comprende grupos acilo monovalentes alifáticos y grupos de la fórmula -C(O)-R-COOH, R siendo un grupo hidrocarburo divalente, tiene las siguientes propiedades: i) el grado de neutralización de los grupos -C(O)-R-COOH no es más de 0.4, ii) el grado total de la sustitución de éster es desde 0.10 hasta 0.70, y iii) el éter de celulosa esterificado tiene una solubilidad en agua de al menos 2.0 porciento en peso a 2 C. SUMMARY OF THE INVENTION The present invention relates to an esterified cellulose ether comprising aliphatic monovalent acyl groups and groups of the formula -C (O) -R-COOH, R being a divalent hydrocarbon group, has the following properties: i) the degree of neutralization of the groups -C (O) -R-COOH is not more than 0.4, ii) the total degree of ester substitution is from 0.10 to 0.70, and iii) the esterified cellulose ether has a solubility in water of at least 2.0 weight percent at 2 C.

Water-soluble ethers substituted with alkenyl or alkyl succinic acid esters

A method for the production of new derivatives of watersoluble cellulose ethers by the reaction of 100 parts by weight of a water-soluble cellulose ether with 3 to 30 parts by weight of C 8-18 alkyl(ene) succinic acid anhydride, in the absence of water and under neutral or acid conditions at elevated temperature, until, in analytically detectable terms, 1 to 8% by weight, based on the cellulose ether, of alk(en)yl succinic acid has reacted with the cellulose molecule; the products of the method; and their use as thickners for aqueous surfactant solutions, dye dispersions, and for hydraulically setting building materials or their use as protective colloids or emulsifiers in the suspension polymerization of water-insoluble monomers in aqueous phase.

Hydroxypropyl methyl cellulose acetate succinate with enhanced acetate and succinate substitution

Process for producing esterified cellulose ether dispersions

一种生产包含分散的酯化纤维素醚的水性组合物的方法包含以下步骤：在水性稀释剂存在下，研磨酯化纤维素醚，其包含(i)式‑C(O)‑R‑COOA的基团或(ii)脂肪族单价酰基和式‑C(O)‑R‑COOA的基团的组合，其中R是二价脂肪族或芳香族烃基并且A是氢或阳离子，将脂肪酸盐与酯化纤维素醚掺合，并选择水性稀释剂、酯化纤维素醚和脂肪酸盐的量，使得所产生的水性组合物包含至少20％的分散的酯化纤维素醚，以及在研磨步骤期间或之后将水性组合物加热至37至80℃的温度。

Process for producing esterified cellulose ethers of very high molecular weight and low viscosity

Cellulose derivative and method for producing the same, cellulose resin composition, molded matter and method for making the same, and electrical and electronic equipment housing

A cellulose derivative obtained from cellulose by substitution of hydrocarbyl groups ranging in carbon number from 1 to 7 and aliphatic acyl groups ranging in carbon number from 4 to 11 for at least part of the hydrogen atoms of hydroxyl groups contained in the cellulose. The cellulose derivative can exhibit good thermal plasticity, strength, heat resistance and mold working suitability.

Hydroxypropyl methyl cellulose acetate succinate with enhanced acetate and succinate substitution.

Se describen polímeros de acetato succinato de hidroxipropil metil celulosa (HPMCAS) con grados únicos de substitución de grupos hidroxipropoxi, metoxi, acetilo y succinoilo. Cuando se usan para hacer composiciones comprendiendo un agente activo de baja solubilidad y tales polímeros, los polímeros proporcionan concentraciones acuosas incrementadas y/o estabilidad físiça mejorada del agente activo.

Composition containing the neutralized polysaccharide derivative

내용없음 No content

Composite for cellulose fiber dispersion and cellulose fiber composition

Provided are a composite for cellulose fiber dispersion that can inexpensively and sufficiently disperse cellulose fibers, particularly nanocellulose, in a hydrophobic resin and a cellulose fiber composition containing the composite. A composite for cellulose fiber dispersion according to the present invention has a structure in which a vinyl polymer is grafted to a cellulose derivative. A cellulose fiber composition according to the present invention contains the composite and cellulose fibers and more specifically also contains an organic solvent, a resin precursor, or a resin.

All-solid secondary cell, solid electrolyte composition and cell electrode sheet used for same, and method for manufacturing cell electrode sheet and all-solid secondary cell

　An all-solid secondary cell provided with a positive electrode active material layer, a negative electrode active material layer, and an inorganic solid electrolyte layer, wherein at least one of the positive electrode active material layer, the negative electrode active material layer, and the inorganic solid electrolyte layer contains a cellulose polymer and an inorganic solid electrolyte exhibiting conductivity with respect to ions of a metal belonging to group 1 or 2 of the periodic table.

Cellulose complex

本发明涉及一种难以发生分离·凝集的纤维素复合体，更具体地，涉及下述一种纤维素复合体，该纤维素复合体含有纤维素与1种以上的水溶性羧甲基纤维素，使该纤维素复合体以1质量％的量分散于离子交换水中而得的水分散液的tanδ在0.6以下。

Pharmaceutical compositions with enhanced performance and improved processability.

El concepto(s) inventivo(s) actualmente descrito(s) y reivindicado(s) se refiere a un polímero para mejorar el rendimiento de fármaco y mejorar la capacidad de procesamiento. De manera específica, el polímero comprende acetato succinato de hidroxipropilmetilcelulosa (HPMC-AS). En el HPMC-AS, el porcentaje de grado de sustitución total de succinoilo es menor que 12% en la posición C6-OH y mayor que 53% en C3-OH, y el porcentaje de grado de sustitución total de acetilo es mayor que 32% en la posición C6-OH.

Hypromellose acetate succinate, method for producing the same, and composition containing the same

Processes for making cellulose estate/elastomer compositions

A cellulose ester composition is provided comprising at least one cellulose ester and at least one additive selected from the group consisting of a compatibilizer, and a plasticizer. Processes for producing the cellulose ester composition are also provided. In another embodiment, a cellulose ester/elastomer composition is provided comprising at least one elastomer, at least one cellulose ester; and at least one additive; wherein the additive is at least one selected from the group consisting of a compatibilizer and a plasticizer. Processes for producing the cellulose ester/elastomer composition is also provided as well as articles comprising the cellulose ester/elastomer composition.

Include the dispersion of esterified cellulose ether

一种可用于生产胶囊壳的水性组合物包含a)至少一种分散的酯化纤维素醚，其包含(i)式‑C(O)‑R‑COOA的基团或(ii)脂肪族单价酰基和式‑C(O)‑R‑COOA的基团的组合，其中R为二价脂肪族或芳香族烃基并且A为氢或阳离子，以及b)以分散的酯化纤维素醚的重量计，0.05％至20％的至少一种脂肪酸盐，其中分散的酯化纤维素醚颗粒的中值粒度d50为至多7微米，此类中值粒度(d50)为在50质量％的颗粒具有较小等效直径并且50质量％具有较大等效直径下的尺寸。

Polyesters blended with cyclic ester polymers

Uniform, thermoplastic, normally solid blends containing cyclic ester polymers and thermoplastic, normally solid polymer which can be a condensation polymer, and/or an addition polymer of olefinically unsaturated monomers having no more than one hydrogen bonded to each carbon of each olefinically unsaturated group thereof, including such polymers as cellulose derivatives, nylons, polyester polymers, polyoxyalkylenes, polycarbonates, poly(fluorocarbons), coumarone-indene resins, maleic acid or anhydride addition polymers and copolymers, stilbene addition polymers and copolymers, chlorinated polyethers, aromatic poly(hydroxy ether) polymers, polysufones, polypeptides, etc. These novel blends are useful in the production of fibers, films, coatings, adhesives, wire and cable coatings, molding materials, extrusion materials, or shaped articles, having one or more unique properties, such as, dyeability, improved stress crack resistance, improved optical properties, e.g., improved hiding power, low haze, high gloss and/or high light transmission, improved plasticization, improved toughness, improved melt processability, improved impact resistance, and/or improved ability to disperse additives, such as, fillers coloring agents, antioxidants, extenders, etc.

Hydroxypropyl methyl cellulose acetate succinate with increased acetate and succinate substitution

Se describen pol&iacute;meros de succinato acetato de hidroxipropil metil celulosa (HPMCAS, por siglas en ingl&eacute;s) con grados &uacute;nicos de sustituci&oacute;n de grupos de hidroxipropoxi, metoxi, acetilo, y succino&iacute;lo. Cuando se usan en la fabricaci&oacute;n de composiciones que comprenden un agente activo de baja solubilidad y los pol&iacute;meros en cuesti&oacute;n, los pol&iacute;meros proporcionan aumento de las concentraciones acuosas y/o estabilidad f&iacute;sica mejorada del agente activo. Polymers of hydroxypropyl methyl cellulose acetate (HPMCAS) with unique degrees of substitution of hydroxypropoxy, methoxy, acetyl, and succinine groups are described. When used in the manufacture of compositions comprising a low solubility active agent and the polymers in question, the polymers provide increased aqueous concentrations and / or improved physical stability of the active agent.

Hydroxyalkyl alkyl cellulose, method for producing the same, and solid preparation

양호한 유동성과 높은 성형성을 나타내는 히드록시알킬 알킬 셀룰로오스를 제공한다. 구체적으로는, 건식 레이저 회절법에 의한 체적 기준의 평균 입자 직경이 50 내지 100㎛이며, 동적 화상 해석법에 의해 전체 입자를 미립자와 구상 입자와 섬유상 입자로 분류하면, 장섬유상 입자 및 단섬유상 입자의 합계인 상기 섬유상 입자의 상기 전체 입자에 대한 체적 분율이 45 내지 70％이며, 상기 미립자의 상기 전체 입자에 대한 체적 분율이 2.0％ 미만인 히드록시알킬 알킬 셀룰로오스, 및 상기 히드록시알킬 알킬 셀룰로오스를 적어도 포함하는 고형 제제 등을 제공한다. A hydroxyalkyl alkyl cellulose exhibiting good fluidity and high moldability is provided. Specifically, when the average particle size on a volume basis by dry laser diffraction is 50 to 100 μm, and all the particles are classified into fine particles, spherical particles, and fibrous particles by dynamic image analysis, long filamentous particles and short filamentous particles are At least a hydroxyalkyl alkyl cellulose and a hydroxyalkyl alkyl cellulose in which the volume fraction of the total fibrous particles relative to the total particles is 45 to 70% and the volume fraction of the fine particles relative to the total particles is less than 2.0% It provides a solid preparation and the like.