09-01-2014 дата публикации
Номер: US20140011416A1
Принадлежит:
A randomly-oriented 3-D fibrous structure and a method for making the same. The method involves electrospinning a spinning dope with an electrospinning apparatus, wherein the spinning dope comprises: a solvent; a polymer dissolved in the solvent, wherein the dissolved polymer is in subunits having molecular weights that are about 5 to about 150 kDa; and a surfactant; to form one or more fibers that comprise a polymer-surfactant complex and that arrange randomly and evenly in three dimensions when contacting a collecting board of the electrospinning apparatus thereby forming the randomly-oriented 3-D fibrous structure. 2. The method of claim 1 , wherein the polymer is selected from the group consisting of protein claim 1 , synthetic polymer claim 1 , and combinations thereof.3. The method of claim of claim 2 , wherein the protein is selected from the group consisting of plant protein claim 2 , animal protein claim 2 , and combinations thereof.4. The method of claim 1 , wherein the spinning dope has a concentration of the surfactant that is about 5 to about 300 percent by weight of the polymer.5. The method of claim 1 , wherein the surfactant is selected from the group consisting of anionic surfactant claim 1 , cationic surfactant claim 1 , nonionic surfactant claim 1 , zwitterionic surfactant claim 1 , and combinations thereof.6. The method of claim 1 , wherein the solvent is selected from the group consisting of water claim 1 , phosphate buffered saline (PBS) claim 1 , carbonate buffer claim 1 , tris-glycine buffer claim 1 , borate buffer claim 1 , acetate buffer claim 1 , n-cyclohexyl-2-aminoethanesulfonic acid (CHES) buffer claim 1 , citric buffer claim 1 , ethanol claim 1 , chloroform claim 1 , 1 claim 1 ,4-dioxane claim 1 , methanol claim 1 , ethylene glycol claim 1 , acetone claim 1 , ethyl acetate claim 1 , methyl acetate claim 1 , hexane claim 1 , petrol ether claim 1 , citrus terpenes claim 1 , diethyl ether claim 1 , dichloromethane claim 1 , ...
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