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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 9819. Отображено 100.
02-08-2012 дата публикации

Sampling and rejection device

Номер: US20120192949A1
Автор: Kevin Petzoldt
Принадлежит: Individual

A sampling and rejection device for a boiler or steam generating system is described. The sampling and rejection device receives the condensate or fluid and allows a volume of the condensate to liquefy or the fluid to build up in the interior of the sampling and rejection device. One or more conductivity, pH, and temperature sensors or probes are positioned in the sampling and rejection device to measure the condensate. The sampling and rejection device includes a collection vessel to hold and temporarily store the condensate. The sampling and rejection device includes an outlet or a return line (to a central boiler) and a drain line. If the sensor measures undesirable conductivity, pH, or temperature in the condensate in the collection vessel, then a valve to the drain line is opened and the condensate is rejected.

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18-10-2012 дата публикации

Assembly and Method for Measuring Pourable Products

Номер: US20120260743A1
Принадлежит: BUEHLER AG

The invention relates to an assembly and method for cost-effective in-line NIR measurement, in particular for cost-effective in-line NIR measurement of ingredients, quality parameters or in general product characteristics of cereal grains, inter alia, and constituents thereof in product streams ( 3 ) in flour mills or animal feed mills or the like. Using at least one measuring probe ( 1 ), the reflection spectra are advantageously recorded on free-flowing product ( 3 ) in a flow tube and are transmitted to an evaluating device ( 2 ) disposed spatially separately therefrom and having an integrated spectrometer ( 12 ). The measured values determined by the evaluating device ( 2 ) are transmitted to a control unit ( 24 ) or to a management system ( 22 ), where they can be used for monitoring and/or regulating the processes or installations. In comparison to NIR systems used until now, the costs per measuring location can be greatly reduced by the simple product presentation and re-use of the evaluating device.

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31-01-2013 дата публикации

Device for taking a sample of liquid contained in a flexible bag

Номер: US20130028811A1
Принадлежит: B Braun Medical SAS

The application relates to taking a sample of liquid contained in a flexible closed container. The problem to be resolved relates to piercing the wall of the container with a non-cutting piece, whilst obtaining a precise and clean opening for accessing the liquid and preventing any unintended flow or spill of liquid. A device for taking a sample of liquid contained in a flexible bag comprises a first section having a base surface and a film perforating element protruding from the base surface. The device also includes a second section having a base surface surrounding a cavity, adapted for receiving the film perforating element of the first section. The first section has an adhesive surface surrounding the film perforating element, and the second section has an adhesive surface surrounding the cavity. Furthermore, one of the two sections has an opening in the base surface, inside of the adhesive surface.

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28-02-2013 дата публикации

Dual Function Liquid Sampler

Номер: US20130047752A1
Автор: John Linderman
Принадлежит: Individual

In one embodiment, a fluid sampling apparatus is disclosed. The apparatus includes an inlet that is fluidically linked to a vacuum compartment through a one-way intake valve and a storage compartment that is fluidically linked to the vacuum compartment through a one-way exit valve; and a plunger for intaking a sample through the inlet into the vacuum compartment and then pushing the sample into the storage compartment. A method of fabrication and use are provided.

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28-03-2013 дата публикации

Sampling device and method of use thereof

Номер: US20130074581A1
Принадлежит: Mettler Toledo AG

An sampling device for capturing a material sample and a method of using said device to process said material sample in situ within the device. Embodiments of the invention may be disposed as elongate probes having extendable sample capture elements. A sample capture element of such a device may include a sample capture pocket located near a distal end thereof for capturing and trapping a sample of material. The sample capture pocket may be provided with a port for receiving material therein and a port for expelling material therefrom. These ports may be placed in communication with corresponding material transfer channels extending through the sample capture element to allow for the in situ processing of a material sample, and the subsequent discharge of the sample to an analyzer or another downstream location.

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14-11-2013 дата публикации

In situ marine sample collection system and methods

Номер: US20130298702A1
Принадлежит: Woods Hole Oceanographic Institute WHOI

According to one aspect, the invention relates to a marine sample collection system adapted for in situ use. The system includes a first filter head and a second filter head for filtering material of interest from ambient marine fluid passing therethrough and a respective filter flow meter disposed downstream of each of the filter heads for measuring volumetric flow through each filter head. The system also includes a pump downstream of the filter heads for inducing flow through the filter heads and an outlet flow meter disposed downstream of the pump for measuring volumetric flow through the pump. An optional controller compares a sum of an output of the flow meters associated with the first and second filter heads and an output of the outlet flow meter to determine if there is leakage in the system.

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01-01-2015 дата публикации

System, Apparatus, and method for Measuring Surface Materials

Номер: US20150000375A1
Принадлежит: Desert Research Institute DRI

In one embodiment, the present disclosure provides a particulate monitoring system. The system includes a vehicle. A wake conditioner is mounted in the vehicle. A sample inlet is placed in communication with an engineered vehicle wake that will be produced by the wake conditioner when the vehicle is in motion.

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01-01-2015 дата публикации

SAMPLE PROCESSING APPARATUS AND AN ERROR DETECTING METHOD FOR SAMPLE PROCESSING APPARATUS

Номер: US20150000428A1
Принадлежит:

A sample processing apparatus comprises an aspirating member which comprises a pump at one side and which is configured to aspirate a sample from the other side, a sensor which is configured to sense the presence or absence of a liquid at a predetermined position of the aspirating member, and a controller which is programmed to execute operations. The operations comprise controlling the aspirating member to aspirate a sample, obtaining a first sensing result by the sensor when the aspirating member aspirates a sample, controlling the aspirating member to aspirate air after aspirating a sample, obtaining a second sensing result by the sensor when the aspirating member aspirates air, and detecting an error in the aspirating operation, based on the first sensing result and the second sensing result. 1. A sample processing apparatus , comprising:an aspirating member which comprises a pump at one side and which is configured to aspirate a sample from the other side;a sensor which is configured to sense the presence or absence of a liquid at a predetermined position of the aspirating member; anda controller which is programmed to execute operations, wherein the operations comprise:controlling the aspirating member to aspirate a sample;obtaining a first sensing result by the sensor when the aspirating member aspirates a sample;controlling the aspirating member to aspirate air after aspirating a sample;obtaining a second sensing result by the sensor when the aspirating member aspirates air; anddetecting an error in the aspirating operation, based on the first sensing result and the second sensing result.2. The sample processing apparatus of claim 1 , whereinthe aspirating member comprises an aspirating pipette on the other side; andthe aspirating pipette aspirates sample in a container through an aspiration orifice.3. The sample processing apparatus of claim 2 , whereinthe controller elevates the aspirating pipette to position the aspiration orifice outside the sample when ...

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04-01-2018 дата публикации

Single-Platform Integrated Aquatic Species and Habitat Sampling System

Номер: US20180001974A1
Автор: Joseph Merz

Low or no disturbance sampling can be accomplished such as through a single-platform aquatic species and habitat sampling system with data integration and rapid processing capabilities that can address the need for sampling at variable depths over varied habitats, along with the simultaneous collection of linked physical and biological data. The platform may be based on a 24-36 foot boat, and may include a net mouth opener brace for an adjustable concentrator net and smaller drift net which may be attached to an adjustable sample chamber, perhaps containing variable mesh capture nets as well as cameras, water sampling equipment, and water quality sensors integrated with a fish finder, GPS, and other monitoring and data recording equipment. The depth of the net mouth opener brace and sample chamber may be adjustable using a depth control.

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07-01-2016 дата публикации

Single-Platform Integrated Aquatic Species and Habitat Sampling System

Номер: US20160003713A1
Автор: Merz Joseph
Принадлежит:

Low or no disturbance sampling can be accomplished such as through a single-platform aquatic species and habitat sampling system with data integration and rapid processing capabilities that can address the need for sampling at variable depths over varied habitats, along with the simultaneous collection of linked physical and biological data. The platform may be based on a 24-36 foot boat, and may include a net mouth opener brace for an adjustable concentrator net and smaller drift net which may be attached to an adjustable sample chamber, perhaps containing variable mesh capture nets as well as cameras, water sampling equipment, and water quality sensors integrated with a fish finder, GPS, and other monitoring and data recording equipment. The depth of the net mouth opener brace and sample chamber may be adjustable using a depth control. 1. An aquatic sampling platform comprising:a boat;a net mouth opener brace mounted substantially to the fore of said boat;a concentrator net comprising a front end and a back end, said front end adjustably attached to said net mouth opener brace;a first depth control to which said concentrator net is immediately responsive;an organismically unrestrictive live well;a drift net mounted to said front end of said concentrator net;a tube connecting said drift net to said organismically unrestrictive live well;a second depth control to which said organismically unrestrictive live well is responsive;at least one organismically unrestrictive live well continuous monitoring multienvironmental sensor;at least one noninvasive aquatic species genetic material sampling system integrated into said organismically unrestrictive live well; anda through-hull immediate access hatch from said boat to said organismically unrestrictive live well.228-. (canceled)29. A multiple aquatic environment sampling platform comprising:a boat;a net mouth opener brace mounted to said boat;a concentrator net comprising a front end and a back end, said front end ...

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02-01-2020 дата публикации

Pressure Reduction System and Method for Reducing the Pressure of High Pressure Aerosols

Номер: US20200003662A1
Принадлежит:

A pressure reduction system and methods therefore that include features for reducing the pressure of a high pressure aerosol to ambient pressure without significantly changing the characteristics of the aerosol are provided. In this manner, the non-volatile particulate matter concentration in a sample stream obtained from the aerosol stream at ambient pressure is representative of the non-volatile particulate matter concentration that was present in the aerosol stream at high pressure prior to the pressure reduction. 1. A pressure reduction system , comprising:an enclosure defining a first chamber and a second chamber positioned downstream of the first chamber;an inlet port fluidly connecting a high pressure environment and the first chamber, the inlet port defining a first expansion orifice through which an aerosol stream comprised of non-volatile particulates is delivered to the first chamber from the high pressure environment, wherein the aerosol stream has a first pressure drop after passing through the first expansion orifice from a high pressure to an intermediate pressure;a transition tube fluidly connecting the first chamber and the second chamber, the transition tube defining an inlet and a second expansion orifice through which the aerosol stream is delivered to the second chamber from the first chamber, wherein the aerosol stream has a second pressure drop after passing through the second expansion from the intermediate pressure to a low pressure; anda sample outlet port defining a sample outlet of the second chamber, wherein a portion of the aerosol stream having the low pressure is configured to flow through the sample outlet.2. The pressure reduction system of claim 1 , wherein the pressure reduction system defines a main axis claim 1 , and wherein the inlet of the transition tube is concentrically aligned with the first expansion orifice of the inlet port along the main axis.3. The pressure reduction system of claim 1 , wherein the first expansion ...

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07-01-2021 дата публикации

Soil Sampling Apparatus

Номер: US20210003483A1
Автор: DeWind Ryan
Принадлежит:

A soil sample collection apparatus is comprised of an extension member, a soil sample collection container, and a collection panel. The extension member includes first and second ends. The soil sample collection container includes first and second ends, the first end of the soil sample collection container being coupled to the second end of the extension member. The collection panel is proximate to the first end of the soil sample collection container, the collection panel moveable to an open position during collection of a soil sample and a closed position during extraction of the soil sample.

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07-01-2021 дата публикации

Device and method for determining liquid contact and liquid volume in a liquid dispenser based on sound

Номер: US20210003484A1
Автор: Pei-Ming WU, Sandor Kovacs
Принадлежит: MESO SCALE TECHNOLOGIES LLC

Devices and methods for determining whether a contact of a liquid dispenser with a liquid based on sound and/or for determining a liquid volume in the liquid dispenser are provided. According to an embodiment, the liquid dispenser includes a sound generator and an acoustic sensor, and at least one of the sound generator or the acoustic sensor is disposed within the dispense chamber portion. According to an embodiment, the liquid dispenser includes a sound generator and an acoustic sensor, and further includes one or more side conduits, where at least one of the sound generator or the acoustic sensor is disposed within a cavity of a respective one of the one or more side conduits, wherein the cavity and a connector of each of the one or more side conduits are free from resonance within a frequency range of the sound sensed by the acoustic sensor.

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07-01-2021 дата публикации

KETONE BODY SENSING DEVICE AND METHOD

Номер: US20210003564A1
Принадлежит:

Devices, patch sensors, and methods for detecting a ketone body are disclosed. An exemplary device includes a collection apparatus for collecting a sample amount of interstitial fluid and a ketone body indicator having an initial negative state and having a positive state when at least a threshold value of the ketone body is collected in the sample amount.

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03-01-2019 дата публикации

Speed Loop for Take-Off and Return by Single Pipeline Probe

Номер: US20190003932A1
Автор: Rolston Claude A.
Принадлежит: MUSTANG SAMPLING LLC

A sample take-off system incorporating a small volume pump with a speed loop for pressurizing excess extracted sample for return into the process stream using a single multi-channel probe for both take-off and return of the excess extracted sample is illustrated and described. 1. A sample probe system comprising:an elongated sample extraction probe having a fluid sample extraction port, an extracted fluid sample exit port, a first extracted fluid communication channel extending generally axially in a direction of elongation of the sample extraction probe for a first select length sufficient to extend between the fluid sample extraction port and the extracted fluid sample exit port, the sample probe defining a return fluid sample reinjection input, a return fluid sample reinjection outlet, and a second reinjection fluid communication channel extending axially for a second select length generally parallel to at least a portion of the first extracted fluid communication channel,the first axially extending channel establishing fluid communication of a first select length between the fluid sample source and the extracted fluid sample exit port and the second axially extending channel defining a second select length extending a select axial distance along the probe;a sample take-off line in fluid communication with the extracted fluid sample exit port;a sample return line connected to the sample take-off line and in fluid communication with the return fluid sample reinjection outlet; and,a pump disposed along the sample return line upstream of the return fluid sample reinjection outlet, the pump for increasing the pressure of return fluid sample in the sample return line to pressurize fluid sample passing therethrough to provide a speed loop reinjection system.2. The system of where the sample probe defines a unitary structure and the first select length corresponds to the entire length of elongation of the probe and the second select length is less than the first select ...

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03-01-2019 дата публикации

SYSTEM AND METHOD FOR DESORBING AND DETECTING AN ANALYTE SORBED ON A SOLID PHASE MICROEXTRACTION DEVICE

Номер: US20190003936A1
Принадлежит:

Disclosed herein is a system for desorbing and detecting an analyte sorbed on a solid phase microextraction (SPME) device. This SPME device The system includes a desorption chamber containing solvent required for desorption of analytes from SPME device; a flow injector in fluid connection with the desorption chamber, the desorption chamber and the flow injector being fluidly connected by at least a flow-insulating fluid connector; a solvent source in fluid connection with the flow injector; and a fluid switch that: in a desorption position, allows the solvent to be sprayed from the flow injector while flow-insulating any desorption solution in the desorption chamber, and in an detecting position, turns off the solvent source while maintaining the fluid connection between the flow injector and the desorption chamber, transferring the desorption solution through the flow-insulating fluid connector to the flow injector as a substantially undiluted plug of liquid. The SPME device can be configured to be various morphologies such as, fibers, blades, thin film membranes and even magnetic particles. When magnetic particles are used an additional holder that contains an embedded magnet which holds a plate with a well to hold said magnetic particles is added to the system. 1. A system for desorbing and detecting an analyte sorbed on a solid phase microextraction (SPME) device , the system comprising:a desorption chamber containing the desorption fluid forming a dome in contact with said SPME device;a flow injector in fluid connection with the desorption chamber, the desorption chamber and the flow injector being fluidly connected by at least a flow-insulating fluid connector;a solvent source in fluid connection with the flow injector; and (a) in a desorption position, allows the solvent to be sprayed from the flow injector while flow-insulating any desorption solution in the desorption chamber, and', '(b) in an detecting position, isolates the solvent source from the flow ...

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08-01-2015 дата публикации

Sampling Separation Module for Subsea or Surface Application

Номер: US20150007648A1
Принадлежит:

The disclosure describes a system to segregate, enrich and capture oil, water and gas samples from a multiphase flow. The system can be used in a subsea location, on the surface or in any other condition where it is connected to a flow of different phases of gas and/or liquid. The samples obtained are representative in composition of the phases flowing at well head conditions in terms of both pressure and temperature. Additionally, a relatively small volume of each phase is used in obtaining the samples. The system connects and disconnects to ports installed at the sampling location nearby the wellhead or the production line. The sampling flow is controlled by means of a pump. The collected samples are separated in mono (or nearly mono)—phase samples (oil, water and gas) and stored in individual bottles. 1. A system for separating and sampling fluid from a multiphase fluid , the system comprising:a separation chamber; andan inlet port operatively connected to the separation chamber at an inlet location for flowing the multiphase fluid into the separation chamber;an upper outlet port operatively connected to the separation chamber at an upper outlet location, the upper outlet location being above the inlet location during operation;a first sensor configured and operatively connected to make measurements indicative of phase content of fluid passing through the upper outlet port;a lower outlet port operatively connected to the separation chamber at a lower outlet location, the lower outlet location being below the inlet location during operation;a second sensor configured and operatively connected to make measurements indicative of phase content of fluid passing through the lower outlet port; anda pumping system adapted and configured to circulate fluid into the separation chamber via the inlet port and out of the separation chamber via the upper outlet port or the lower outlet port, wherein a desired fluid phase is accumulated within the separation chamber.25-. ( ...

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27-01-2022 дата публикации

SAMPLE PRESSURE REDUCING SYSTEM

Номер: US20220026314A1
Автор: Klentzman James T.
Принадлежит:

A sample pressure reducing system is provided that integrates various pressure applications into a single system that provides the end user with a high-integrity sample without damaging equipment. The system facilitates sampling high-pressure product into a low-pressure container. The system fills and transfers product to reduce pressure automatically and repeatedly. 1. A system for sampling a crude oil sample at a reduced pressure , the system comprising:a dual-cavity cylinder comprising each of a first cavity and a second cavity;a piston positioned between the first cavity and the second cavity;a blanket gas applied to the second cavity of the dual-cavity cylinder;a first solenoid;wherein when the first solenoid is activated, sample is provided to the system.2. The system of claim 1 , wherein the system includes a second solenoid claim 1 , and wherein when the second solenoid is activated claim 1 , sample is provided to the first cavity in the dual-cavity cylinder.3. The system of claim 1 , wherein the system includes a sample container from which sample from the dual-cavity cylinder may be transferred when the dual-cavity cylinder reaches a predetermined volume of sample.4. The system of claim 3 , wherein the system includes each of a first actuation valve and a second actuation valve claim 3 , wherein each of the first actuation valve and the second actuation valve are in communication with the dual-cavity cylinder claim 3 , and wherein when the first actuation valve is open claim 3 , sample is provided to the dual-cavity cylinder via the first actuation valve claim 3 , and wherein when the second actuation valve is open claim 3 , sample is provided from the dual-cavity cylinder to the sample container via the second actuation valve.5. The system of claim 1 , wherein the system includes a maximum proximity switch associated with the dual-cavity cylinder claim 1 , and wherein when a volume of sample reaches a predetermined maximum volume in the dual-cavity ...

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27-01-2022 дата публикации

Specimen collector including multiple specimen wells

Номер: US20220026315A1
Принадлежит: Entellect Medical Holdings

A specimen collector for gathering tissue specimens includes a housing extending along a first axis between a first opening and a second opening to define a hollow interior. An inlet port and an outlet port are located axially between the first and second openings. A specimen tray defines a first specimen well and a second specimen well and is slideably disposed within the housing and axially slideable between a first position to dispose the first specimen well in fluid communication with the inlet and outlet ports and a second position to dispose the second specimen well in fluid communication with the inlet and outlet ports. The specimen tray comprises a pair of tray components each defining a respective one of the first and second wells and jointly slideable. The pair of tray components are separable from one another and each individually removable from the housing.

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12-01-2017 дата публикации

Apparatus, System and Method for Selecting a Target Material

Номер: US20170010188A1
Принадлежит: RareCyte, Inc.

This disclosure is directed to a device and a system for picking a target analyte of a suspension. A picker introduces at least one force, such as by a magnetic gradient and/or by a pressure gradient, to extract the target analyte from a specimen. The magnetic gradient may be introduced by a magnet, such as a permanent magnet or an electromagnet, and the pressure gradient may be introduced by a pump which moves within a fluid-primed cannula to create the pressure gradient, thereby drawing the target analyte into the cannula. The picker may also expel the target analyte onto or into a substrate, such as a well plate, after the target analyte has been drawn into the picker by reversing the pressure gradient or removing the magnetic gradient. 1. A system comprising: a pump block comprising a first end and a second end comprising a seal,', 'a piston at least partially housed within the pump block and partially extending through the seal, wherein the piston translates relative to the pump block, and', 'a cannula comprising an adapter end and a tube end, wherein the adapter end is connected to the pump block and the tube end extends away from the pump block;, 'a picker comprising'}a driver;a coupling mating the driver to the piston; anda mount connecting the picker to an imaging or detection device.2. The system of claim 1 , further comprising a light source connected to the picker.3. The system of claim 1 , wherein a full rotation of the piston includes 1-10 claim 1 ,000 steps.4. The system of claim 3 , wherein each step includes 1-10 claim 3 ,000 micro-steps.5. The system of claim 4 , wherein each step or micro-step equates to a volume equal to or less than 1 picoliter claim 4 , 10 picoliters claim 4 , 100 picoliters claim 4 , 1 nanoliter claim 4 , 1 microliter claim 4 , or 1 milliliter.6. The system of claim 1 , further comprising a housing to encase as least a portion of the driver claim 1 , the coupling claim 1 , a first end of the piston claim 1 , and at least a ...

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14-01-2016 дата публикации

SAMPLE-TAKING UNIT

Номер: US20160011082A1
Принадлежит:

A sample-taking unit having a sampling unit and a hold-down device which is movable relative thereto in a parallel manner, said sample-taking unit including a self-holding mechanism which, as a result of a self-locking effect, automatically fixes the hold-down device in a lowered fixing position against an upward movement until the self-locking effect is removed again as a result of the self-holding mechanism being acted upon with a detaching force, preferably as a result of contact between the sampling unit and a clamping element of the self-holding mechanism. 1. A sample-taking unit for taking samples from a container , the sample-taking unit comprising:a) a sampling unit including a penetrating element, wherein the sampling unit is configured to be moved from a second end position into a first end position, in which the penetrating element projects into the container in the second end position, in which the penetrating element does not project into the container in the first end position, and b1) be moved from a fixing position into a release position, in which the hold-down device fixes the container in the fixing position, in which the hold-down device does not act upon the container in the release position, and', 'b2) maintain the fixing position using a holding mechanism whilst the sampling unit is moved from the second end position in a direction of the first end position,, 'b) a hold-down device configured to be moved relative to the penetrating element, wherein the hold-down device is also configured to'}c) in which the holding mechanism is a self-holding mechanism where the hold-down device is fixed in the fixing position as a result of a self-locking effect with a clamping force.2. The sample-taking unit of claim 1 , in that the self-holding mechanism comprises a clamping element and a clamping body between which the self-locking effect is active.3. The sample-taking unit of claim 2 , in that the clamping body comprises a clamping rail.4. The sample- ...

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10-01-2019 дата публикации

SPECIMEN COLLECTION DEVICE, HOLDER FOR SPECIMEN COLLECTION DEVICE, AND SPECIMEN PRE-PROCESSING METHOD THAT USES SPECIMEN COLLECTION DEVICE

Номер: US20190011334A1
Принадлежит: SHIMADZU CORPORATION

This specimen collection device has a channel through which a specimen can be drawn by capillarity. The channel has two channel sections that extend from the tip side to the base side and are connected at the tip side. One of the channel sections is connected to a base side specimen intake port, and the other terminates at a location prior to reaching the base end. An air hole is provided at this terminating location. The specimen collection device is equipped with an extraction unit for collecting a prescribed amount of the specimen. The extraction unit includes the two channel sections on the tip side of the air hole, and can be severed from the other sections of the device body of the specimen collection device via a severable section. 1. A sample collection device comprising:a device main body that has a proximal end and a distal end and that has an opening as a sample suction port on a proximal side thereof;a flow channel for sample collection that is provided in the device main body so as to have a thickness small enough to suck a sample by capillary action and that has two channels connected to each other on a distal side of the device main body and extending from the distal side toward the proximal side of the device main body, one of the channels communicating with the sample suction port and another channel terminating before reaching the proximal end;an air hole that communicates with a terminal of the another channel; andat least one extraction part that includes a portion of the two channels located on a distal side of the air hole of the device main body and that can be cut off from a rest of the device main body by cutting grooves.2. The sample collection device according to claim 1 , whereina position of the at least one extraction part is determined so that when blood is collected as a sample and centrifuged in such a manner that centrifugal force acts in a direction from the proximal end toward the distal end of the device main body, a plasma ...

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10-01-2019 дата публикации

Sampling container for a remotely operated vehicle

Номер: US20190011335A1
Принадлежит: Aquabotix Technology Corp

A sampling container apparatus for a remotely operated vehicle (“ROV”) is disclosed. An example sampling container includes a tank configured to hold a sample collected from an underwater environment. The tank includes at least one opening that contains a plunger therein. The plunger includes a contraction or retraction mechanism that pulls the plunger into the tank causing the plunger to actuate from an open position to a closed position. The plunger is retained in the open position by a retainer plate. To enable the plunger to actuate to the closed position, the tank is rotated relative to the retainer plate, causing the plunger to traverse a travel channel in the retainer plate. The travel channel includes a plunger window, which when reached by the plunger, enables the plunger to be pulled through the retainer plate, thereby sealing the opening of the tank and preserving the collected sample.

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10-01-2019 дата публикации

Instrument for analytical sample preparation

Номер: US20190011338A1
Принадлежит: CEM Corp

An instrument for extraction based molecular sample preparation and related processes is disclosed. The instrument includes a thermally conductive pressure resistant heating chamber and a thermally conductive sample cup positioned in the thermally conductive pressure resistant heating chamber for heating liquids and solids together in the thermally conductive sample cup. A liquid delivery inlet fixture in the thermally conductive pressure resistant heating chamber delivers liquids (solvent) from a supply to the thermally conductive sample cup in the thermally conductive pressure resistant heating chamber, and a chiller in liquid communication with the thermally conductive sample cup in the thermally conductive pressure resistant heating chamber receives heated liquids from the thermally conductive pressure resistant heating chamber when the chamber is opened to atmospheric pressure.

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14-01-2021 дата публикации

FLUID SAMPLE COLLECTION SYSTEM FOR PUMPED FLUID SOURCE

Номер: US20210010911A1
Принадлежит:

A fluid sample collection system for directly collecting a fluid sample from a fluid source includes a fluid collector and a fluid line. The fluid collector includes (i) a sample vial including a sample vial body and a vial cap that is selectively coupled and sealed to the sample vial body; (ii) a collector body that defines a passenger vial chamber, the sample vial being positioned at least partially within the passenger vial chamber during collection of the fluid; and (iii) a cap access facilitator that is configured to engage a portion of the sample vial to enable a user to selectively couple the vial cap to the sample vial body to seal the sample vial so that the fluid is retained within the sample vial. The fluid line extends between the fluid source and the fluid collector to substantially directly transmit the fluid sample to the fluid collector without exposing the fluid sample to the ambient environment that surrounds the fluid sample collection system. 125-. (canceled)26. A fluid sample collection system for directly collecting a fluid sample from a fluid source without exposing the fluid sample to an ambient environment that surrounds the fluid sample collection system , the fluid sample collection system comprising:a fluid collector including:(i) a sample vial that is configured to retain fluid from the fluid source, the sample vial including a sample vial body and a vial cap that is selectively coupled and sealed to the sample vial body;(ii) a collector body that defines a passenger vial chamber, the sample vial being positioned at least partially within the passenger vial chamber during collection of the fluid; and(iii) a cap access facilitator that is configured to engage a portion of the sample vial to enable a user to selectively couple the vial cap to the sample vial body to seal the sample vial so that the fluid is retained within the sample vial; anda fluid line that extends between the fluid source and the fluid collector, the fluid line being ...

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10-01-2019 дата публикации

Sampling device

Номер: US20190011472A1
Автор: Erwin Trummer
Принадлежит: Zeta Biopharma GmbH

A sampling device (1) for filling a sample vessel (4) with sample material from a material container, wherein the sampling device (1) comprises a first locking unit (2), a sterilization unit and a sampling chamber (3), wherein the sampling chamber (3) has an internal chamber space (5), a manipulation unit (6), an opening unit (7) arranged within the internal chamber space (5) as well as a coupling unit (8) arranged within the internal chamber space (5), the first locking unit (2) is arranged between the material container and the coupling unit (8), and the sterilization unit is connected to the internal chamber space (5) and configured to sterilize the internal chamber space (5), wherein the manipulation unit (6) is configured to accommodate the sample vessel (4) at least in part within the internal chamber space (5), movable between the opening unit (7) and the coupling unit (8), the opening unit (7) is configured to open and close the sample vessel (4), and the coupling unit (8) is configured to be coupleable to the sample vessel (4).

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15-01-2015 дата публикации

SAMPLING DEVICE FOR THERMAL ANALYSIS

Номер: US20150013478A1
Принадлежит:

A sampling device comprises a container having an essential cylindrical part and a bottom part. The container further comprises an inner wall member and an outer wall member. The inner wall member and the outer wall member are essentially coaxially arranged in the cylindrical part of the container and joined at the top part of the container, and the inner and outer wall members define a closed insulating space between the outer surface of the inner wall member and the inner surface of the outer wall member. The sampling device further comprises temperature responsive means adapted to extend into the sample quantity during thermal analysis. Spacer means is arranged in the insulating space in the bottom part of the container and/or in the cylindrical part of the container in the vicinity of the bottom part. 1. Sampling device for thermal analysis of solidifying metal , comprising:a container adapted to be immersed into a metal melt and filled with a sample quantity of said metal melt;the container comprising a top part open at the top thereof, a bottom part adapted to be the first part of the container immersed into the melt when taking a sample quantity, and an essentially cylindrical part arranged between the top part and the bottom part;the container further comprising an inner wall member and an outer wall member;the inner wall member having an inner surface intended to contact a sample quantity of the metal melt during thermal analysis, and an outer surface;the outer wall member having an inner surface, and an outer surface adapted to be exposed to the ambient air during thermal analysis;wherein the inner wall member and the outer wall member are essentially coaxially arranged in the essentially cylindrical part of the container and joined at the top part of the container, the inner and outer wall members defining a closed insulating space between the outer surface of the inner wall member and the inner surface of the outer wall member;the sampling device further ...

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09-01-2020 дата публикации

Long-term in-situ sampling and analysis device for sediment pore water and method thereof

Номер: US20200011768A1
Принадлежит: Guangzhou Marine Geological Survey

The present application discloses a long-term, in-situ sampling and analysis device for sediment pore water and a method thereof. The long-term in-situ sampling and analysis device for sediment pore water includes a bracket, a probe, an elevator, a diverting device, a first water storage device, and a second water storage device, a peristaltic pump, a dissolved gas of sediment pore water analysis device and an in-situ environment measurement device. The present application can collect and store the sediment pore water in an in-situ, long-term and time-phased manner, and in low measuring error level.

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03-02-2022 дата публикации

DEVICE FOR CAPTURING IN SITU AQUATIC MICROBIOMES

Номер: US20220033872A1
Принадлежит:

The present disclosure relates to a portable device for collecting and/or concentrating in situ plankton microbiome, configured for submersion in water. The device herein disclosed is a compact and low-cost autonomous biosampler, with the ability to yield DNA samples for later genomic analysis. 1. A portable device for collecting and/or concentrating in situ plankton microbiome configured for submersion in water , comprising:an inlet for water containing the plankton microbiome;an outlet for water depleted of plankton microbiome;a plurality of valves placed between the inlet and the outlet;a set of sensors for measuring flow and pressure;a pump for pumping water from the inlet to the outlet such that water is passed across a filter cartridge,wherein the filter cartridge comprises a plurality of filters for in situ filtration of water containing plankton microbiome;a microcontroller for controlling the opening and closing of a plurality of valves and the speed of water pumping such that the device collects and/or concentrates in situ plankton microbiome;a reservoir containing a preserving solution for preserving nucleic acids.2. The device according to claim 1 , wherein the filter cartridge comprises at least 16 filters each having a pore size of 0.22 μm.3. The device according to claim 1 , comprising at least 2 filter cartridges.4. The device according to claim 1 , wherein the preserving solution is injectable into the filter cartridge.5. The device according to claim 1 , wherein the set of sensors comprises a pressure sensor for controlling and maintaining the pressure of the filter cartridge from 1 bar to 1.3 bar.6. The device according to claim 1 , wherein the set of sensors comprises a flow sensor for detecting and/or controlling the flow of water passing through the filter cartridge.7. The device according to claim 1 , for concentrating in situ plankton microbiome nucleic acids by filtration.8. The device according to claim 1 , wherein said device operates at a ...

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21-01-2016 дата публикации

MICROFLUIDICS CARTRIDGE WITH PIPETTING GUIDE

Номер: US20160016170A1
Принадлежит: TECAN TRADING AG

A disposable cartridge configured as a digital microfluidics system for manipulating samples in liquid portions having a cartridge accommodation site and a central control unit for controlling selection of individual electrodes of an electrode array located at the site and for providing plural electrodes with individual voltage pulses for manipulating liquid portions by electrowetting. The cartridge has a hydrophobic working surface and a rigid cover with a second hydrophobic surface, the hydrophobic surfaces facing each other and being separated in parallel planes by a gap. The cartridge has plural pipetting guides for safe entering/withdrawing liquids into/from the gap with a pipette tip. At least one of the pipetting guides provides an abutting surface sealingly admittable by a counter surface of a pipette tip, located at a pipetting orifice that reaches through the rigid cover, and configured to prevent a pipette tip from touching the hydrophobic working surface.

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03-02-2022 дата публикации

FERMENTATION MONITORING SYSTEM

Номер: US20220034760A1
Принадлежит:

A method and system for monitoring wine fermentation is provided. The system comprises a sensor conduit and a sensor enclosure. The sensor enclosure comprises a leveling indicator that indicates if the sensor conduit is vertical. 120-. (canceled)21. A system for monitoring , wherein the system comprises:a conduit;at least three legs; and the enclosure comprises a level configured to indicate when the conduit is vertical,', 'the at least three legs enable the conduit to be vertically positioned for monitoring, and', 'each of the at least three legs is individually adjustable in height., 'an enclosure operably coupled to the conduit and the at least three legs, wherein22. The system according to claim 21 , wherein the level comprises a bubble level.23. The system according to claim 21 , wherein the system is operable to monitor wine fermentation.24. The system according to claim 21 , wherein the system is operable to monitor a vat.25. The system according to claim 21 , wherein a filter is coupled to the enclosure.26. The system according to claim 21 , wherein an antenna is coupled to the enclosure.27. The system according to claim 21 , wherein the system is operable to monitor wine fermentation in a barrel.28. The system according to claim 21 , wherein the conduit extends through a bung.29. The system according to claim 28 , wherein a size of the bung is selected according to a bung hole of a barrel claim 28 , and wherein the hung is interchangeable with bungs of other diameters.30. The system according to claim 28 , wherein the bung is made of a material that degrades over time claim 28 , and wherein a degraded bung is interchangeable with a new bung.31. A method for monitoring claim 28 , wherein the method comprises:inserting a conduit into a container, wherein the conduit is operably coupled to an enclosure; and the level indicates when the conduit is vertical,', 'the enclosure is coupled to a plurality of legs, and', 'positioning the enclosure comprises adjusting ...

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19-01-2017 дата публикации

SELF-SEALING SAMPLING PORT FOR SANITARY PIPING

Номер: US20170016806A1
Автор: Dupont, SR. Paul Robert
Принадлежит:

A system is provided allowing for sanitary sampling of piping without disassembly thereof, the system having: a sampling port disposed in communication with a pipe, the sampling port having a distal portion in communication with an interior of the pipe and a proximal opening; a pressure retention ring having an open central portion, the pressure retention ring being configured to engage the proximal opening of the sampling port; and a septum disposed between the sampling port and the pressure retention ring having a lower section, an upper section and a central portion, wherein the lower section comprises an elastomeric portion of a first hardness having a diameter that is substantially the same as the interior diameter of the sampling port, wherein the upper section comprises an elastomeric portion of a second hardness having a diameter that is substantially the same as the interior diameter of the open central portion of the pressure retention ring, wherein the central portion of the septum extending from the respective diameters of the upper and lower sections substantially to the outer diameter of the pressure retention ring and substantially flat portion of the sampling port, acting as a gasket, wherein the second hardness is harder than the first hardness; wherein a sanitary sample is taken by inserting a cannula through the septum, extracting the sanitary sample and removing the cannula from the septum. 1. A system allowing for sanitary sampling of piping without disassembly thereof , the system comprising:a sampling port disposed in communication with a pipe, said sampling port comprising a distal portion in communication with an interior of said pipe and a proximal opening;a pressure retention ring comprising an open central portion, said pressure retention ring being configured to engage said proximal opening of said sampling port; anda septum disposed between said sampling port and said pressure retention ring comprising a lower section, an upper section ...

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21-01-2016 дата публикации

Device and method for drawing a liquid from a process tank

Номер: US20160018296A1

A device for drawing a liquid from a process tank, in particular, a process tank to be protected from contamination, comprising: a first receptacle for receiving the liquid withdrawn from the process tank. A first liquid line, connecting the process tank with the first receptacle and having a first end that can be connected with the process tank and a second end opening into the first receptacle; and at least one first valve assembly, which is arranged between the first and second ends of the first liquid line and is designed to block or release liquid transport through the first liquid line. The device has at least one pressure sensor, which is connected with the first receptacle, in particular, for detecting a pressure prevailing within the first receptacle and/or is arranged at the second end of the first liquid line. The device is designed to transport liquid from the process tank to the first receptacle in a first operating mode, characterized in that the device is designed to block liquid transport from the process tank to the first receptacle in a second operating mode, wherein said device is designed such that a pressure difference (p 1 −p 2 ) between the first and the second ends of the first liquid line is greater than or equal to zero, in particular, greater than a predetermined permissible minimum value greater than or equal to zero, in particular, greater than a predetermined minimum value, both in the first operating mode and the second operating mode and as long as the first end of the first liquid line is connected with the process tank and the process tank is to be protected from contamination.

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17-04-2014 дата публикации

Devices and methods for determination of bioavailability of pollutants

Номер: US20140102182A1

Contaminant mass collection in saturated sedimentary environments for bioavailability determination. A casing includes a screen between the environment that is subject to sampling, such as a saturated sediment and the device itself. The casing includes a water intake zone, a pump, and sorptive media. The water intake zone, the pump, the screen and the sorptive media, are all operably linked in sequence. The screened casing is secured to form an in situ device; the screen is in fluid communication with the water intake zone and excludes endemic sediments and aquatic life. The in situ device is deployed in the saturated sedimentary environment. The pump operates to concentrate analytes from the selected environment in the sorptive media, where the concentrated analytes include the analyte mass of time-weighted fluid samples.

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21-01-2021 дата публикации

METHOD FOR ASSESSING THE LETHALITY AND THE LEVEL OF CROSS CONTAMINATION CONTROL OF A PROCESS NON-INVASIVELY

Номер: US20210017574A1
Принадлежит:

Methods and devices for non-invasively assessing lethality and/or cross contamination of a process. In some embodiments, an aggregating sampler is used, such as a fixture catcher, to obtain samples before, after and/or during the process. In some embodiments, an isolated packet of bacteria is exposed to the active elements of the process without contacting the product. In other embodiments, a method to measure lethality using microgenomic analysis is reported. In still other embodiments, a procedure is reported to use the knowledge from a microgenomic process to use direct qPCR for identified genera species to measure cross contamination. These metrics have special utility in the validation of wash water performance but may have utility is assessing process performance when unpackaged product is treated as for blanching and irradiation. Process performance can include verification of process delivery or for research. 1. A method for measuring a lethality of a process that is compatible with use during commercial food processing operations , the method comprising:obtaining a before measure of microbial load of one or more genera or species of abundant wild type bacteria selected to serve as surrogates for one or more target organisms;obtaining an after measure of microbial load of the same abundant wild type bacteria; andreporting the log of the ratios of abundance as the lethality.2. The method of measuring lethality of where an aggregating sampler is used to collect sample of the abundant wild type bacteria for enumeration from which the after and/or the before measures are obtained.3. The method of measuring lethality of where the aggregating sampler is one or more fixed catchers.4. The method of where relative metagenomic levels and a reference enumeration are used to measure either or both of the before and after measures of microbial load.5. The method of where thiosulfate is used to quench residual sanitizer for analysis.6. The method of where metagenomic ...

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16-01-2020 дата публикации

Passive Micro-vessel and Sensor

Номер: US20200018152A1
Автор: Angelescu Dan E.
Принадлежит:

An electrically passive device and method for in-situ acoustic emission, and/or releasing, sampling and/or measuring of a fluid or various material(s) is provided. The device may provide a robust timing mechanism to release, sample and/or perform measurements on a predefined schedule, and, in various embodiments, emits an acoustic signal sequence(s) that may be used for triangulation of the device position within, for example, a hydrocarbon reservoir or a living body. 1. A device comprising:an isolated cavity that is initially inaccessible to an external fluid;a device body including one or more structural elements supporting a mechanical structure, the mechanical structure separating the isolated cavity from the external fluid;a piercing structure for piercing the mechanical structure; anda membrane, wherein pressure applied to the membrane drives the piercing structure into the mechanical structure, causing the mechanical structure to collapse, rupture and/or fracture, opening a passage for the external fluid to enter the isolated cavity.2. The device according to claim 1 , wherein the isolated cavity is in fluidic communication with a sampling chamber.3. The device according to claim 2 , further comprising a tube coupled to the isolated cavity claim 2 , the tube further coupled to a sampling chamber such that external fluid from the isolated cavity can flow into the sampling chamber.4. The device according to claim 1 , further including a one-way check valve between the isolated cavity and the sampling chamber that allows fluid flow into the sampling chamber.5. The device according to claim 1 , further comprising an electrically passive timing mechanism including a fluidic timing cavity claim 1 , wherein at the end of a timing interval fluid within the timing cavity drives the piercing structure into the mechanical structure claim 1 , causing the mechanical structure to collapse claim 1 , rupture and/or fracture.6. The device according to claim 5 , wherein the ...

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16-01-2020 дата публикации

DEVICE FOR MULTI-PARAMETER INTEGRATED MONITORING OF DEEP SUBMARINE TURBIDITY CURRENT

Номер: US20200018678A1
Принадлежит: OCEAN UNIVERSITY OF CHINA

A device for multi-parameter integrated monitoring of a deep submarine turbidity current primarily includes cement pile pore-pressure monitoring, optical turbidity monitoring, floating ball flow velocity monitoring, and turbidity current sediment sampling, can observe the turbidity, excess pore pressure, flow velocity, and other parameters of the turbidity current, can fulfill simultaneous and real-time transmission for in-situ monitoring, and can complete multiple tasks at the same observing position, so that the situation where the sampling position and the observing position are different due to the movement of an apparatus along with a ship during ordinary work is avoided. 1. A device for multi-parameter integrated monitoring of a deep submarine turbidity current , comprising:an upper part and a lower part; [ 'a plurality of water-permeable stone rings are clamped in the cement pile in a spaced manner in a vertical direction and have an outer diameter identical to an outer diameter of the cement pile and an inner diameter identical to an outer diameter of the casing pipe;', 'the lower part comprises a cement pile, and a casing pipe embedded into the cement pile to form a combined-type pore-pressure monitoring probe rod;'}, 'a plurality of inner water-permeable stones and a plurality of FBG pore-pressure sensors are arranged on an inner wall of the casing pipe and are located on the water-permeable stone rings, the plurality of FBG pore-pressure sensors have bottoms connected with the plurality of inner water-permeable stones and upper parts connected with a top water-permeable stone, seawater from above enters the probe rod through the top water-permeable stone, and a pressure of the seawater and a pore pressure of seabed sediments act on the plurality of FBG pore-pressure sensors;', a control circuit board and a slide rail are mounted in the glass cover, a scattered light receiving system and an infrared excitation light source configured for emitting an ...

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26-01-2017 дата публикации

Method and apparatus for acquiring blood for testing

Номер: US20170023446A1
Принадлежит: NEOTERYX LLC

A blood sampling device is provided having holder with a manipulating end and an absorbent probe on the opposing end. The probe is made of pyrolyzed porous carbon sized to directly absorb a predetermined volume of liquid, preferably biological fluid, in a predetermined amount of time. Shapes for absorbent probes of differing materials are provided.

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10-02-2022 дата публикации

SUBSTRATE ANALYZING METHOD AND SUBSTRATE ANALYZING DEVICE

Номер: US20220042882A1
Принадлежит: IAS, INC.

A substrate analysis method using a nozzle for substrate analysis which discharges an analysis liquid from a tip thereof, scans a substrate surface with a discharged analysis liquid, and sucks the analysis liquid. This is done by arranging a liquid catch plate that catches the discharged analysis liquid, thus retaining analysis liquid discharged between the nozzle tip and the liquid catch plate; positioning the substrate so that the end part thereof can be inserted between the nozzle tip and the liquid catch plate; bringing the end part of the substrate into contact with analysis liquid retained between the nozzle tip and liquid catch plate; and moving the nozzle and liquid catch plate concurrently along a periphery of the substrate, while keeping the end part of the substrate in contact with the analysis liquid, to analyze the end part of the substrate. 1. An analysis method of a substrate by use of a nozzle for substrate analysis , which discharges an analysis liquid from a tip of the nozzle , scans a surface of the substrate with a discharged analysis liquid , and then sucks the analysis liquid , comprising the steps of:arranging, opposite to a nozzle tip, a liquid catch plate that catches the discharged analysis liquid, to thereby retain the analysis liquid discharged from the tip between the nozzle tip and the liquid catch plate;positioning the substrate so that the end part thereof can be inserted between the nozzle tip and the liquid catch plate;bringing the end part of the substrate into contact with the analysis liquid retained between the nozzle tip and the liquid catch plate; andmoving the nozzle and the liquid catch plate concurrently along a periphery of the substrate, while keeping the end part of the substrate in contact with the analysis liquid, to thereby analyze the end part of the substrate.2. The analysis method of a substrate according to claim 1 , wherein the liquid catch plate is hydrophobic.3. The analysis method of a substrate according to ...

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24-01-2019 дата публикации

AUTOSAMPLER

Номер: US20190025161A1
Автор: Nakamura Takafumi
Принадлежит: SHIMADZU CORPORATION

An autosampler includes a pressure release operation unit for performing, by controlling operation of a needle drive mechanism and a switching mechanism, before a tip end of a needle is pulled out from an injection port following a state where a sampling channel is disposed between a feeding device and an analytical column, a pressure release operation of switching the switching mechanism in such a way that the sampling channel is not disposed between the feeding device and the analytical column and a system including the sampling channel is made an open system, and of performing standby until a pressure inside the sampling channel is returned to atmospheric pressure. 1. An autosampler comprising:a sampling channel including, at one end, a needle for suctioning a sample from a sample container containing a sample, and including a sample loop for retaining the sample suctioned through the needle;a needle drive mechanism for moving the needle;an injection port that is connected to the sampling channel by insertion of a tip end of the needle;a switching mechanism for switching, when the tip end of the needle is inserted in the injection port, to one of a state where the sampling channel is disposed between a feeding device for feeding a mobile phase and an analytical column for separating a sample into components and a state where the sampling channel is not disposed between the feeding device and the analytical column, and for switching, in a state where the sampling channel is not disposed between the feeding device and the analytical column, a system including the sampling channel between an open system and a closed system; anda pressure release operation unit for performing, by controlling operation of the needle drive mechanism and the switching mechanism, before the tip end of the needle is pulled out from the injection port following a state where the sampling channel is disposed between the feeding device and the analytical column, a pressure release operation ...

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28-01-2021 дата публикации

STERILE SAMPLING APPARATUS

Номер: US20210024869A1
Принадлежит:

A sterile sampling apparatus includes a first to seventh flow paths, a sampling section, a first and second pumps, and a first to sixth opening/closing mechanism. The sampling section is disposed in the seventh flow path. The first pump is disposed in the sixth flow path. The second pump is disposed in the seventh flow path. The second flow path includes a first opening/closing mechanism. The third flow path includes a second opening/closing mechanism. The fourth flow path includes a third opening/closing mechanism. The first flow path includes a fourth opening/closing mechanism. The sixth flow path includes a fifth opening/closing mechanism. The seventh flow path includes a sixth opening/closing mechanism. The rate of the second pump is higher than that of the first pump. 1. A sterile sampling apparatus comprising:a first flow path configured to be connected to a first tank for accommodating a culture medium containing cells;a second flow path configured to be connected to a second tank for accommodating a buffer solution;a third flow path configured to communicate with ambient air:a fourth flow path includes a first branch portion where the second flow path and the third flow path are configured to be joined together;a fifth flow path includes a second branch portion where the first flow path and the fourth flow path are configured to be joined together;a sixth flow path configured to branch off from a third branch portion which is downstream of the fifth flow path;a seventh flow path configured to branch off from the third branch portion; anda sampling section configured to be disposed in the seventh flow path,wherein a first pump that sends a fluid in the sixth flow path is disposed in the sixth flow path,wherein a second pump that sends a fluid in the seventh flow path is disposed in the seventh flow path,wherein the second flow path includes a first opening/closing mechanism,wherein the third flow path includes a second opening/closing mechanism,wherein the ...

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29-01-2015 дата публикации

SAMPLE TAKING DEVICE

Номер: US20150031072A1
Принадлежит: HEXASCREEN CULTURE TECHNOLOGIES, S.L.

Sample taking device for extracting a fluid sample from a vessel comprising: a cover portion for closing the vessel such that, in use a headspace is defined between the cover portion and fluid held in the vessel, a sampling chamber comprising a sampling inlet and a sampling outlet, a cannula adapted to provide, in use, fluid communication between the fluid held in the vessel and the sampling chamber through the sampling inlet, and ports to operate the device in at least two operating conditions: a sample preparing condition in which a pressure in the headspace is greater than that of the sampling chamber such that fluid flows through the cannula towards the sampling chamber and can be retained therein, and a sample dispensing condition in which fluid retained in the sampling chamber can be delivered through the sampling outlet and fluid remaining inside the cannula can return to the vessel. 1. A sample taking device for extracting a fluid sample from a vessel comprising:a cover portion suitable for closing the vessel such that, in use, a headspace is defined between the cover portion and a fluid held in the vessel,a sampling chamber comprising a sampling inlet and a sampling outlet,a cannula configured to provide, in use, fluid communication between the fluid held in the vessel and the sampling chamber through the sampling inlet, and a) a sample preparing condition in which a pressure in the headspace is greater than that of the sampling chamber such that fluid flows through the cannula towards the sampling chamber and can be retained therein, and', 'b) a sample dispensing condition in which fluid retained in the sampling chamber can be delivered through the sampling outlet and fluid remaining inside the cannula can return to the vessel., 'ports configured to operate the device in at least two operating conditions2. A sample taking device of claim 1 , wherein in the sample dispensing condition a pressure in the sampling chamber is greater than that of the headspace. ...

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17-02-2022 дата публикации

DUAL DELIVERY NEEDLE WASH SYSTEM

Номер: US20220048035A1
Принадлежит: WATERS TECHNOLOGIES CORPORATION

Described herein are systems and methods used for washing needle assemblies with multiple needles. 1. A system for washing a needle assembly having a first needle and a second needle , the system comprising:a wash tower comprising an elongate body defining an opening in a top surface thereof and a passageway extending downwardly therefrom;a first port disposed proximate the top surface of the wash tower and in fluid communication with the passageway;a second port disposed proximate a bottom surface of the wash tower and in fluid communication with the passageway;a pumping system configured to deliver a wash solution to at least one of the first port or the second port; andan aspiration system configured to engage at least a portion of the needle assembly so as to evacuate any wash solution or solution vapors resident in the needle assembly or the wash tower.2. The system of claim 1 , wherein the pumping system is configured to deliver the wash solution to the first port and the second port simultaneously.3. The system of claim 2 , wherein the opening is configured to at least partially receive the needle assembly and the first needle is a puncture needle having an outer diameter and an inner diameter and the second needle is a sample needle disposable within the inner diameter of the puncture needle.4. The system of claim 3 , wherein the aspiration system is in fluid communication with the inner diameter of the puncture needle.5. The system of further comprising a seal assembly disposed at a distal end of the passageway and configured to engage a distal end of the sample needle.6. The system of further comprising a force sensor configured to provide feedback on the engagement of the sample needle with the seal assembly.7. The system of further comprising a stop mechanism configured to control movement of the needle assembly relative to the wash tower.8. The system of further comprising a controller in electrical communication with the pumping system claim 3 , the ...

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31-01-2019 дата публикации

DEVICE AND METHOD FOR DRAWING A LIQUID FROM A PROCESS TANK

Номер: US20190033176A1
Принадлежит:

The application discloses a device for drawing a liquid from a process tank to be protected from contamination, including: a first receptacle for receiving the liquid withdrawn from the process tank; a first liquid line connecting the process tank with the first receptacle; and at least one first valve assembly disposed in the first liquid line and designed to block or release liquid transport through the first liquid line. The device includes at least one pressure sensor for detecting a pressure within the first receptacle. The device is designed such that a pressure difference between the first and the second ends of the first liquid line is greater than a predetermined minimum value when the first liquid line is connected with the process tank and the process tank is to be protected from contamination. 1. A liquid sample drawing device , comprising:a receptacle embodied to receive and to contain a liquid sample;a liquid line having a first end and a second end, wherein the first end is embodied to connect to a process tank, and wherein the second end opens into the receptacle;a valve assembly disposed in the liquid line between the first end and the second end, wherein the valve assembly is configured to selectively block or allow liquid transport through the liquid line;a pressure sensor connected with the receptacle and configured to measure a pressure within the receptacle and to output a pressure measurement signal based on the measured pressure;a gas pressure controller connected with the receptacle via a gas line opening into the receptacle, wherein the gas pressure controller is configured to control and to regulate a gas pressure in the receptacle; anda control unit configured to receive the pressure measurement signal from the pressure sensor and further configured to control the valve assembly and the gas pressure controller,wherein the control unit is further configured to regulate and to control, based on the pressure measurement signal, a pressure ...

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31-01-2019 дата публикации

Pathologic Staging Compression Apparatus And Methods

Номер: US20190033178A1
Автор: Bodell Alex, Stern Charles
Принадлежит: Parker Isaac Instruments, LLC

A filtration assembly for separating solids from liquids contained in a sample, and a method for preparing such a sample are disclosed herein. According to one embodiment, the filtration assembly includes an inner element () with proximal and distal ends () and a sample () disposed therein. A reinforcing sleeve () is disposed around the inner element () to form a sample receiver () with proximal and distal ends (). A filter () is disposed at the open proximal end of the sample receiver () and a filtrate receiver () is placed over the filter () and threadedly engaged with the sample receiver () to clamp the filter () therebetween. Then, the receivers () are inverted and a pressure is applied to the sample () to force a liquid component () through the filter () into the filtrate receiver (), while solids () are retained in the sample receiver (). 1. A method of treating a sample including a solid tissue and a solvent bearing fat dissolved from the solid tissue comprising:(a) placing the sample in contact with a filter;(b) applying pressure to the sample so as to force the solvent and fat through the filter while retaining the solid tissue on the filter and compressing the solid tissue;(c) controlling the pressure-applying step so as to compress the solid tissue to a predetermined degree; and(d) recovering the compressed solid tissue.2. The method according to claim 1 , wherein the step of placing the sample in contact with a filter includes placing the sample in a bore of a sample receiver claim 1 , and securing a filter adjacent a proximal end of the bore so that the sample is disposed between a piston and the filter claim 1 , and wherein the pressure-applying step pressure includes urging the piston disposed in the bore toward the proximal end and toward the filter.3. The method according to claim 2 , wherein the step of controlling the pressure-applying step includes controlling the magnitude of a force applied to the piston to urge the piston toward the proximal ...

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30-01-2020 дата публикации

METHODS AND SYSTEMS FOR PREPARING CYTOLOGICAL SAMPLES

Номер: US20200033238A1
Автор: Musat Sorin
Принадлежит:

The disclosed methods for preparing cytological samples may include placing a cytological sample in a concave filter in a filtration system, applying a negative pressure to an outer side of the concave filter with a vacuum device to withdraw a liquid from the cytological sample, applying a sectionable matrix material over the filtered cellular material within the concave filter, and removing an assembly including the filtered cellular material and the sectionable matrix material from the filtration system. Various other related methods, systems, and materials are also disclosed. 1. A method for preparing cytological samples , the method comprising:placing a cytological sample in a concave filter in a filtration system;applying a negative pressure to an outer side of the concave filter with a vacuum device to withdraw a liquid from the cytological sample and to maintain a filtered cellular material on an inner surface of the concave filter;applying a sectionable matrix material over the filtered cellular material within the concave filter; andremoving an assembly including the filtered cellular material and the sectionable matrix material from the filtration system.2. The method of claim 1 , wherein applying the sectionable matrix material over the filtered cellular material comprises applying a liquid or molten sectionable matrix material over the filtered cellular material.3. The method of claim 2 , further comprising hardening the sectionable matrix material to form the assembly including the filtered cellular material and the sectionable matrix material.4. The method of claim 1 , wherein applying the sectionable matrix material over the filtered cellular material comprises applying a pre-formed and pre-shaped sectionable matrix material over the filtered cellular material.5. The method of claim 1 , further comprising positioning a lower sectionable matrix material under the concave filter prior to applying the negative pressure to the outer side of the concave ...

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04-02-2021 дата публикации

METHOD FOR DOSING AN AMOUNT OF LIQUID WITH A PERISTALTIC PUMP

Номер: US20210033500A1
Принадлежит:

The present disclosure conveys a method for dosing an amount of liquid with a peristaltic pump in an analyzer, wherein the analyzer is configured to determine a concentration of a measurand of a sample, wherein the peristaltic pump includes at least one rotor having at least two rollers, the method comprising the steps: determining the position of at least one roller of the peristaltic pump; moving the rotor of the peristaltic pump to an initial position if it is not already in an initial position; and dosing the amount of liquid to be conveyed by moving the rotor by counting roller passes through a reference position. The present disclosure further discloses an analyzer for implementing the method. 1. A method for dosing an amount of liquid with a peristaltic pump in an analyzer configured to determine a concentration of a measurand of a sample , the method comprising:providing a peristaltic pump that includes a tube and at least one rotor including at least two rollers, which are configured to contact and deform the tube, the tube having an inlet side and an outlet side;determining a position of at least one of the at least two rollers of the peristaltic pump;moving the at least one roller into an initial position when the at least one roller is not yet in an initial position; anddosing a desired amount of liquid by moving the at least one roller by counting roller passes through a reference position.2. The method of claim 1 , further comprising discarding contents of the tube of the peristaltic pump disposed in a region of the tube that is on the outlet side before the initial position is reached.3. An analyzer for determining a concentration of a measurand of a liquid sample claim 1 , the analyzer comprising:a peristaltic pump that includes a tube and at least one rotor including at least two rollers, which are configured to contact and deform the tube, the tube having an inlet side and an outlet side; and{'claim-ref': {'@idref': 'CLM-00001', 'claim 1'}, 'a data ...

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04-02-2021 дата публикации

APPARATUS AND METHOD FOR ANALYSING AND PROCESSING GRANULAR MATERIAL

Номер: US20210033547A1
Принадлежит:

A method of analysing granular material in a slurry, the method comprising: compacting the granular material in the slurry to form one or more pucks; irradiating said pucks with X-Ray radiation and detecting X-ray energy transmitted through said one or more irradiated pucks; irradiating a reference material with X-Ray radiation, said reference material having known material characteristics and detecting X-ray energy transmitted through said reference material; comparing X-ray energy transmission through said one or more pucks with the reference material to compute, using a processing unit, one or more particle characteristics of the granular material in the one or more pucks. 1. A method of analysing granular material in a slurry , the method comprising:compacting the granular material in the slurry to form one or more pucks;irradiating a section of said pucks with X-Ray radiation and detecting X-ray energy transmission through said one or more irradiated pucks;irradiating a section of reference material with X-Ray radiation, said reference material having known material characteristics and detecting X-ray energy transmitted though said reference material; andcomparing X ray energy transmission through said one or more pucks with the reference material to compute, using a processing unit, one or more particle characteristics of the granular material in the one or more pucks.2. A method of analysing granular material in the slurry in accordance with wherein the step of comparing X ray energy transmission through said one or more pucks with the reference puck is used for computing average density or relative average density of the granular material in the one or more pucks.3. A method of analysing granular material in the slurry in accordance with wherein the step of forming said one or more pucks comprises the steps of directing one or more streams of slurry into a collection chamber claim 1 , filtering said slurry to separate the granular material from the slurry ...

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24-02-2022 дата публикации

DEVICE FOR SAMPLING SOIL OF TROPICAL LOWLAND RAINFOREST

Номер: US20220057300A1

The present invention discloses a device for sampling soil of tropical lowland rainforest, comprising a driving motor, a probe rod and a sampling barrel. An output shaft of the driving motor is fixedly connected with the top end of the probe rod. The probe rod is hollow. The sampling barrel is disposed in the probe rod. An opening of the bottom end of the sampling barrel faces to the soil inlet. Two baffle plates are also arranged in the probe rod. The side wall of the baffle plate is arc-shaped, and the bottom end of the baffle plate is semicircular. The semicircular baffle plates can pass through the space and can be jointed to form a cylinder with a closed bottom end. Two linear motors are fixedly arranged in the probe rod and can respectively drive the two baffle plates to move. 1. A device for sampling soil of tropical lowland rainforest , comprising a driving motor , a probe rod and a sampling barrel , wherein an output shaft of the driving motor is fixedly connected with a top end of the probe rod; a spiral coil is fixedly arranged on an outer wall of the probe rod; the probe rod is hollow , and a soil inlet is formed in a bottom end of the probe rod; the sampling barrel is disposed in the probe rod; an opening of the bottom end of the sampling barrel faces to the soil inlet; the sampling barrel is detachably connected with the probe rod; a space is reserved between the bottom end of the sampling barrel and the soil inlet; two baffle plates are arranged in the probe rod; the side wall of the baffle plate is arc-shaped , and the bottom end of the baffle plate is semicircular; the semicircular baffle plates can pass through the space and can be jointed to form a cylinder with a closed bottom end; two linear motors are fixedly arranged in the probe rod to respectively drive the two baffle plates to move; the probe rod is further internally provided with a power supply , a programmable logic controller (PLC) and a displacement sensor; the linear motors , the ...

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24-02-2022 дата публикации

Pressure Controlled Fluid Sampler and Method

Номер: US20220057301A1
Принадлежит:

A fluid sampler system includes a fluidic head including a gas aperture capable of communication with a pressurized gas source, a liquid conduit capable of communication with a sample reservoir, and a seal capable of forming a compression seal to the sample reservoir when gas pressure is applied to the sample reservoir through the gas aperture and capable of displacing a portion of the sample through the liquid conduit; and a positioning apparatus capable of positioning the fluidic head and the sample reservoir in communication with one another. A method for providing an aliquot of sample, includes forming a releasable compression seal to a reservoir including a liquid sample; pressurizing the reservoir with compressed gas; displacing an aliquot of the sample from the reservoir; and transferring the displaced aliquot of the sample to a location. 1. A method for providing an aliquot of sample , comprising:forming a releasable compression seal to a first reservoir comprising a first liquid sample;pressurizing the first reservoir with compressed gas;submerging a conduit in the first liquid;displacing a first aliquot of the first liquid sample from the first reservoir into the conduit;isolating a desired amount of the first aliquot by controlling the filling of the conduit by removing the conduit from the first liquid and controlling the pressure in the first reservoir; andtransferring the displaced first aliquot of the first liquid sample to a first location.2. The method of claim 1 , wherein isolating a desired amount of the first aliquot comprises measuring the presence of a fluid claim 1 , flow rate claim 1 , fluid volume or fluid interface of the displaced first aliquot of the first liquid sample and adjusting the pressure of the compressed gas.3. The method of claim 1 , further comprising providing an inline sensor capable of detecting a fluid or fluid interface.4. The method of claim 1 , further comprising:forming a releasable compression seal to a second ...

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24-02-2022 дата публикации

METHODS AND COMPOSITIONS FOR EXOSOME-BASED DIAGNOSTICS AND DIAGNOSIS OF DISEASE

Номер: US20220057392A1
Принадлежит:

The invention encompasses an innovative system for exosome-based diagnostics of infection and/or inflammation that is based on a novel exosome isolation kit from biological fluids such as urine and saliva in the form of a syringe, and a rapid diagnostic test device that simultaneously detects exosomal biomarkers based on a quantitative assay and disease (infection/inflammation) biomarkers. 1. An exosome collection device comprising:a. a syringe;b. three integrated filters incorporated into the syringe;c. an exosome collection opening;wherein the first filter is about 0.1 to about 1.0 micrometer filter with pores at the level of 150 ml,the second filter is about 0.20 to about 0.30 micrometer filter at the level of 100 ml,the third filter is about 250 to about 750 kDalton filter at the level of 50 ml, andwherein the exosome collection opening comprises an penetrable opening to allow collection of the exosomes using a needle and syringe.2. The exosome collection device of claim 1 , wherein the first filter is a 0.8 micrometer filter with pores at the level of 150 ml.3. The exosome collection device of claim 1 , wherein the second filter is a 0.22 micrometer filter at the level of 100 ml claim 1 , and4. The exosome collection device of claim 1 , wherein the third filter is a 500 kDalton filter at the level of 50 ml.5. The exosome collection device of claim 1 , wherein the exosomes are isolated from biological fluids claim 1 , including blood claim 1 , blood plasma claim 1 , sweat claim 1 , urine claim 1 , and saliva.6. The exosome collection device of claim 5 , wherein the biological fluid sample is urine.7. The exosome collection device of claim 6 , wherein the urine has been treated with a protease inhibitor.8. The exosome collection device of claim 1 , wherein the exosomes are urinary exosomes.9. The exosome collection device of claim 1 , wherein the integrated filters is a fiber-based filtration cartridge.109. The exosome collection device of claim 1 , wherein the ...

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07-02-2019 дата публикации

In-Line Thermal Isolator for Liquid Sample Conditioning

Номер: US20190041298A1
Автор: Rolston Claude A.
Принадлежит: MUSTANG SAMPLING LLC

A generally cylindrical, elongated thermal isolator for in-line placement proximate to a vaporizer of a sample take-off conditioning system for minimizing upstream heat migration from a sample vaporizer to prevent liquid sample pre-vaporization. 1. An in-line thermal isolator disposed proximate to an entry port of a sample vaporizer to minimize heat migration axially from a sample vaporizer to an upstream sample conduit , the isolator featuring an elongated , generally cylindrical body incorporating an axial bore for accommodating fluid flow from a sample source and a threaded fitting member adapted for in-line sealable connection with a mating threaded member formed in said sample conduit.2. The in-line thermal isolator of formed from a polymeric material selected from the group consisting of PETE and PEEK.3. The in-line thermal isolator of where the axial bore restricts fluid flow.4. The in-line thermal isolator of where the thermal isolator includes compression fittings on each end.5. The in-line thermal isolator of where the thermal isolator defines a unitary cylindrical structure female threaded fittings recessed in each end.6. The system of further characterized by the material for the thermal isolator being selected from the group consisting of synthetic polymers and ceramics.7. A method of preventing further thermally-induced sample pre-vaporization sample conduit comprising the step of inserting an isolator according to upstream from a sample vaporizer in the sample conduit line to prevent heat migration.8. (canceled)9. An in-line fluid conduit thermal isolator comprising:a generally tubular body of a select length defining a first end and a second end, said tubular body being composed of a heat-transfer insulating material and including axial bore extending through the select length for fluid passage from an upstream fluid inlet to a downstream fluid outlet, said first end including a first mating element of a first cooperating interengagable sealing ...

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16-02-2017 дата публикации

SYSTEMS, DEVICES, AND METHODS FOR BODILY FLUID SAMPLE COLLECTION

Номер: US20170042460A1
Принадлежит:

Bodily fluid sample collection systems, devices, and method are provided. The device may comprise a first portion comprising at least a sample collection channel configured to draw the fluid sample into the sample collection channel via a first type of motive force. The sample collection device may include a second portion comprising a sample container for receiving the bodily fluid sample collected in the sample collection channel, the sample container operably engagable to be in fluid communication with the collection channel, whereupon when fluid communication is established, the container provides a second motive force different from the first motive force to move a majority of the bodily fluid sample from the channel into the container. 1. A device for collecting a bodily fluid sample , the device comprising:a first portion comprising a plurality of capillary sample collection channels;a second portion comprising a plurality of sample containers for receiving the bodily fluid sample collected in the sample collection channels, wherein the sample containers have gas permeable and penetration re-sealable enclosure, wherein the gas permeable closure allows for sample to be transferred from the capillary channels to the containers without having to use a separate motive force.2. A device for collecting a bodily fluid sample , the device comprising:a first portion comprising a plurality of capillary sample collection channels;a second portion comprising a plurality of sample containers for receiving the bodily fluid sample collected in the sample collection channels, wherein the sample containers have gas permeable and penetration re-sealable enclosure, wherein the gas permeable closure allows for sample to be transferred from the capillary channels to the containers without having to use a separate motive force, wherein a flow facilitator to provide a favorable pathway to from the channels into the container.369-. (canceled)70. The device of claim 1 , wherein an ...

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15-02-2018 дата публикации

LIQUID SAMPLING

Номер: US20180045616A1
Принадлежит:

The invention provides a liquid sampler for the automated sampling of liquids at dedicated pre-determined intervals. The liquid sampler includes a liquid inlet connectable to a liquid circuit containing a liquid to be sampled, a sampling reservoir for collecting a liquid sample, and a sampling pump connected to the liquid inlet, operable to extract a discrete amount of liquid from the liquid inlet and to discharge the discrete amount of liquid into the sampling reservoir. 1. A liquid sampler , which includes:a liquid inlet connectable to a liquid circuit containing a liquid to be sampled;a sampling reservoir for collecting a liquid sample; anda sampling pump, the sampling pump connected to the liquid inlet, operable to extract a discrete amount of liquid from the liquid inlet and to discharge the discrete amount of liquid into the sampling reservoir.2. The liquid sampler of claim 1 , wherein liquid inlet includes a flow control valve claim 1 , such as a restriction valve claim 1 , operable to control any one or both of the flow and pressure of the liquid from the liquid inlet to the sampling pump.3. The liquid sampler of claim 2 , which includes a liquid flow chamber connected to the liquid inlet claim 2 , the liquid flow chamber providing a constant volume of fresh liquid for extraction by the sampling pump.4. The liquid sampler of claim 3 , wherein the liquid flow chamber includes an output port providing flow communication with the sampling pump.5. The liquid sampler of or claim 3 , wherein the liquid flow chamber includes a liquid outlet connectable to a liquid circuit containing the liquid to be sampled claim 3 , for returning the excess fresh liquid to the liquid circuit.6. The liquid sampler of any one of to claim 3 , which includes a liquid conditioning sensor in communication with a liquid to be sampled.7. The liquid sampler of claim 6 , wherein the liquid conditioning sensor is a di-electric sensor.8. The liquid sampler of any one of to claim 6 , which ...

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13-02-2020 дата публикации

SYSTEMS, DEVICES, AND METHODS FOR POINT-OF-USE TESTING FOR FLUID CONTAMINATION

Номер: US20200047093A1
Принадлежит:

Systems, devices, and methods for detecting contamination (e.g., bacteria) in fluid are provided. The systems, devices, and methods allow for filtering a fluid sample using a filter to capture and concentrate cells (e.g., bacteria) to detect electrochemical properties thereof. The cells can be exposed to a reagent that diffuses into the cells to produce a product of interest that can be used in analysis of the fluid sample. The product of interest can diffuse out of the filter into a fluid storage component for detection and analysis by an analysis component. After the sampling is completed, the filter can be detached and discarded. Other aspects of the present disclosure, including enhancements and various systems and methods for concentrating cells and analyzing the same, are also provided. 1. A system for sampling fluid , comprising:a filter housing having an inlet and an outlet;at least one filter disposed in the filter housing;a fluid storage chamber in fluid communication with the at least one filter;at least one electrode in fluid communication with the at least one filter; andone or more reagents located in at least one of the filter housing, the at least one filter, and one or more electrodes of the at least one electrode,wherein the filter housing and the at least one filter are configured such that one or more cells contained within a fluid sample that is passed into the filter housing via the inlet becomes located in at least one concentration region disposed in the filter housing and reacts with the one or more reagents to produce one or more redox species, the one or more redox species being part of fluid from the fluid sample and other material that passes out of the filter housing via the outlet, andwherein the one or more electrodes of the at least one electrode is configured to measure one or more electrochemical properties of the produced one or more redox species.2. The system of claim 1 ,wherein the inlet of the filter housing is disposed on a ...

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14-02-2019 дата публикации

Sample Probe for Dissolution Testing and the Like

Номер: US20190049344A1
Принадлежит: DISTEK, INC.

In one embodiment, a sample probe has a cap and a base, wherein the cap includes a grip portion and a projection portion. The projection portion fits within a hollow portion of a filter such that the filter is disposed on the outside of the projection portion and the filter and the cap form a cap assemblage. The base comprises a base recess that receives a portion of the cap assemblage including the filter. The cap and base include corresponding media transfer regions adjacent and connected to the filter that reduces flow resistance and chances of blockage and/or contamination during dissolution-testing sampling using the sample probe. 11100. An article of manufacture (e.g. , ) comprising:{'b': 1102', '1504', '1503', '1504, 'a cap (e.g., ) having a projection (e.g., ) with a duct (e.g., ) through the projection (e.g., ); and'}{'b': 1101', '1403', '1401', '1402', '1403', '1101, 'claim-text': [{'b': 1504', '1701', '1201', '1102', '1201, 'the projection (e.g., ) is adapted to fit within a recess (e.g., ) of a filter (e.g., ) to form a cap-filter assemblage (e.g., /);'}, {'b': 1201', '1102', '1201', '1403', '1101', '1102', '1201', '1101, 'the filter (e.g., ) and the projection of the cap-filter assemblage (e.g., /) are adapted to fit within the recess (e.g., ) of the base (e.g., ) to form a cap-filter-base assemblage (e.g., //);'}, {'b': 1102', '1201', '1101', '1201, 'the cap-filter-base assemblage (e.g., //) defines at least one media transfer region adjacent to the filter (e.g., ); and'}, {'b': 1401', '1402', '1101', '1102', '1201', '1101', '1103', '1100, 'the duct (e.g., /) of the base (e.g., ) in the cap-filter-base assemblage (e.g., //) is adapted to receive a cannula (e.g., ) to form a sample probe (e.g., ).'}], 'a base (e.g., ) having a recess (e.g., ) and a duct (e.g., /) in fluid communication with the recess (e.g., ) of the base (e.g., ) wherein2150411021701120112011504110212011504. The article of claim 1 , wherein the projection (e.g. claim 1 , ) of the cap ( ...

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13-02-2020 дата публикации

APPARATUS AND METHOD FOR ANALYSING A SOLID SPECIMEN MATERIAL

Номер: US20200049597A1
Принадлежит: TECHNISCHE UNIVERSITÄT WIEN

An apparatus and a method for analysing a solid specimen material by means of ablating particles of the solid specimen material by laser into a carrier liquid, having: a specimen holder for arranging the solid specimen material covered by the carrier liquid, a laser apparatus for irradiating the solid specimen material to produce a suspension of particles of the solid specimen material and the carrier liquid, an analysis apparatus for analysing the particles, an ablation cell with the specimen holder, having a liquid channel for the carrier liquid and having an entry window made of a material that transmits the laser beam, a supply line for supplying the carrier liquid into the liquid channel of the ablation cell and a discharge line for discharging the suspension of particles of the solid specimen material and the carrier liquid from the liquid channel of the ablation cell into the analysis apparatus. 1. A device for analysing a solid sample material by means of laser ablation of particles of the solid sample material in a carrier liquid , comprising:a sample holder for positioning the solid sample material covered with the carrier liquid;a laser device for irradiating the solid sample material with a laser beam in a manner such that a suspension of particles of the solid sample material and of the carrier liquid can be produced,an analytical device for analysing the particles of the solid sample material,wherein the sample holder is in an ablation cell comprising a liquid channel for the carrier liquid and an entry window produced from a material that is transparent to the laser beam of the laser device,a supply line to supply the carrier liquid to the liquid channel of the ablation cell,a discharge line to discharge the suspension of particles of the solid sample material and of the carrier liquid from the liquid channel of the ablation cell to the analytical device anda dosing device for introducing a defined volume of a standard liquid into the supply line.2. ...

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13-02-2020 дата публикации

Liquid dispenser with manifold mount for modular independently-actuated pipette channels

Номер: US20200049727A1
Принадлежит: Becton Dickinson and Co

Automated pipetting systems and methods are disclosed for aspirating and dispensing fluids, particularly biological samples. In one aspect, a liquid dispenser includes a manifold and one or more pipette channels. The manifold includes a vacuum channel, a pressure channel, and a plurality of lanes. Each lane includes an electrical connector, a port to the pressure channel, and a port to the vacuum channel. The pipette channels can be modular. Each pipette channel includes a single dispense head and can be selectively and independently coupled to any one lane of the plurality of lanes. In some aspects, a valve in the pipette channel is in simultaneous fluid communication with a pressure port and a vacuum port of the manifold. The valve selectively diverts gas under pressure and gas under vacuum to the dispense head in response to control signals received through the electrical connector of the manifold.

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10-03-2022 дата публикации

GREASE EVALUATION

Номер: US20220074916A1
Принадлежит:

Methods of evaluating viscous compositions are disclosed. The methods may be used to evaluate degradation levels of lubricants including grease. The methods may include preparing a surface for testing by leveling and flattening a viscous composition, placing a drop of a liquid on the flattened leveled surface, evaluating the observed contact angle between the drop and the surface, and then comparing the observed contact angle to a reference contact angle. 1. A method of evaluating lubricant comprising:a. acquiring a sample of a mechanically used grease from a mechanical device;{'claim-text': ['i. orienting a portion of the sample to level and', 'ii. flattening the portion of the sample;'], '#text': 'b. preparing a grease surface for testing by'}c. placing a drop of a liquid on the grease surface;d. evaluating an observed contact angle between the drop and the grease surface; ande. comparing the observed contact angle to a reference contact angle;f. wherein the mechanically used grease is degraded as compared to a pristine grease of the same type.2. The method of wherein the mechanically used grease has experienced bleed off as compared to the pristine grease of the same type.3. The method of wherein the mechanically used grease has experienced oxidation as compared to the pristine grease of the same type.4. The method of wherein the mechanically used grease has experienced mechanical degradation as compared to the pristine grease of the same type.5. The method of wherein the mechanically used grease has experienced contamination as compared to the pristine grease of the same type.6. The method of wherein the mechanically used grease has experienced water contamination as compared to the pristine grease of the same type.7. The method of wherein the observed contact angle correlates with the kinematic viscosity of the mechanically used grease across varying degradation levels for a degradation type wherein the degradation type is selected from bleed off claim 1 , ...

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10-03-2022 дата публикации

LIQUID DISPENSER WITH MANIFOLD MOUNT FOR MODULAR INDEPENDENTLY-ACTUATED PIPETTE CHANNELS

Номер: US20220074962A1
Принадлежит:

Automated pipetting systems and methods are disclosed for aspirating and dispensing fluids, particularly biological samples. In one aspect, a liquid dispenser includes a manifold and one or more pipette channels. The manifold includes a vacuum channel, a pressure channel, and a plurality of lanes. Each lane includes an electrical connector, a port to the pressure channel, and a port to the vacuum channel. The pipette channels can be modular. Each pipette channel includes a single dispense head and can be selectively and independently coupled to any one lane of the plurality of lanes. In some aspects, a valve in the pipette channel is in simultaneous fluid communication with a pressure port and a vacuum port of the manifold. The valve selectively diverts gas under pressure and gas under vacuum to the dispense head in response to control signals received through the electrical connector of the manifold. 1170-. (canceled)171. A kit comprising:{'claim-text': ['a pressure channel,', 'a vacuum channel,', 'a plurality of pressure cross-channels, each pressure cross-channel beginning at the pressure channel and terminating at a surface of the manifold, and', 'a plurality of vacuum cross-channels, each vacuum cross-channel beginning at the vacuum channel and terminating at the surface of the manifold; and'], '#text': 'a manifold comprising:'}{'claim-text': ['a single dispense head,', 'a pressure port configured to receive gas under pressure from one pressure cross-channel, and', 'a vacuum port configured to receive gas under vacuum from one vacuum cross-channel,', 'wherein each of the plurality of pipette channels is configured to selectively and independently couple to the manifold.'], '#text': 'a plurality of pipette channels, each of the plurality of pipette channels comprising:'}172. The kit of claim 171 , wherein the pressure channel and the vacuum channel are physically and fluidically isolated from each other within the manifold.173. The kit of claim 172 , wherein ...

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20-02-2020 дата публикации

Sample collection system for interplanetary vehicle

Номер: US20200055619A1
Принадлежит: Honeybee Robotics LLC

A system and method of acquiring and delivering samples, such as in association with an interplanetary vehicle is provided. The system includes a gas delivery assembly having a storage tank with a compressed gas. A sampler device is provided having a hollow interior, the hollow interior having a curved and angled surface, an open end and an exit end. A plurality of nozzles are fluidly coupled between the hollow interior and the storage tank, at least one of the plurality of nozzles arranged to direct the compressed gas towards the exit end. A sample capture assembly is further provided having a container fluidly coupled to the exit end.

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02-03-2017 дата публикации

PATHOLOGIC STAGING COMPRESSION APPARATUS AND METHODS

Номер: US20170059455A1
Автор: Bodell Alex, Stern Charles
Принадлежит:

A filtration assembly for separating solids from liquids contained in a sample, and a method for preparing such a sample are disclosed herein. According to one embodiment, the filtration assembly includes an inner element () with proximal and distal ends () and a sample () disposed therein. A reinforcing sleeve () is disposed around the inner element () to form a sample receiver () with proximal and distal ends (). A filter () is disposed at the open proximal end of the sample receiver () and a filtrate receiver () is placed over the filter () and threadedly engaged with the sample receiver () to clamp the filter () therebetween. Then, the receivers () are inverted and a pressure is applied to the sample () to force a liquid component () through the filter () into the filtrate receiver (), while solids () are retained in the sample receiver (). 1. A method of treating a sample including a solid tissue and a solvent bearing fat dissolved from the solid tissue comprising:(a) placing the sample in contact with a filter;(b) applying pressure to the sample so as to force the solvent and fat through the filter while retaining the solid tissue on the filter and compressing the solid tissue;(c) controlling the pressure-applying step so as to compress the solid tissue to a predetermined degree; and(d) recovering the compressed solid tissue.2. The method according to claim 1 , wherein the step of placing the sample in contact with a filter includes placing the sample in a bore of a sample receiver claim 1 , and securing a filter adjacent a proximal end of the bore so that the sample is disposed between a piston and the filter claim 1 , and wherein the pressure-applying step pressure includes urging the piston disposed in the bore toward the proximal end and toward the filter.3. The method according to claim 2 , wherein the step of controlling the pressure-applying step includes controlling the magnitude of a force applied to the piston to urge the piston toward the proximal ...

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04-03-2021 дата публикации

Cryogenic Liquid Composite Sampling Systems and Methods

Номер: US20210063285A1
Принадлежит: MUSTANG SAMPLING LLC

A cryogenic liquid sampling system including a chamber having affixed therein a sample pump to pull a cryogenic liquid sample from an external source and an enclosure. The enclosure includes a supply port to receive an input stream of a gas, an input port connected to the chamber via a vacuum line, a sample pump port connected to the chamber via a pump line and configured to feed therethrough gas received at the supply port to the sample pump, a vacuum device connected to the input port and configured to generate a vacuum within the chamber by pulling air from the vacuum line, and processing circuitry to control the vacuum device and the sample pump to perform transfer of a cryogenic liquid sample from the external source to an external device.

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04-03-2021 дата публикации

FLUID SAMPLING VESSEL AND SYSTEM

Номер: US20210063286A1
Автор: HALL Bernard
Принадлежит: Checkfluid Inc.

A fluid sampling system and fluid sampling vessel therefor permit sampling of fluids from industrial machines or fluid storage containers using one hand while being able to retain sampled fluids without spillage and without permitting contaminants to enter the sampling bottle before, during and/or after sampling. 1. A fluid sampling vessel comprising:a bottle having a mouth; a sampling port through a top of the cap fluidly connecting an interior volume of the bottle with an external environment,', 'an open-ended conduit extending from the sampling port at an underside of the cap into the bottle when the cap is engaged with the bottle so that fluid entering the sampling port from the external environment can flow from a first end of the conduit to a second end of the conduit into the bottle, the conduit comprising a guide portion proximate the first end and a valve retaining portion proximate the second end and longitudinally aligned with the guide portion, the guide portion separated from the valve retaining portion by a valve seat;, 'a cap for the bottle, the cap comprising a rim sealingly engageable with the mouth of the bottle,'}a spring-loaded ball valve situated in the valve retaining portion, the spring-loaded ball valve comprising a ball and a spring, the ball seated on the spring and biased by the spring toward the valve seat, the ball preventing fluid from flowing between the guide portion and the valve retaining portion when the ball is seated on the valve seat and permitting fluid to flow between the guide portion and the valve retaining portion when the ball is pushed away from the valve seat against the bias of the spring; anda removable retainer mounted proximate the second end of the conduit, the retainer preventing the spring and the ball from exiting the conduit through the second end while permitting fluid to flow out of the conduit into the bottle.2. The vessel of claim 1 , wherein the rim is sealingly engageable with the mouth of the bottle by a ...

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12-03-2015 дата публикации

Systems and Methods for Incubating Samples

Номер: US20150072378A1
Автор: Kokawa Hidesuke
Принадлежит:

Provided are incubation systems for incubating samples for an assay. In certain aspects, the systems include a rotary platform, a sample container positioned at a peripheral edge of the platform, a plurality of activity sites including at least a first and a second activity site, a processor, and a memory that includes instructions. When executed by the processor, the instructions cause the system to rotate the rotary platform to move the sample container from the first activity site to the second activity site, extract a first portion of the sample from the sample container at the first activity site for a measurement based on a first incubation time period, and extract a second portion of the sample from the sample container at the second activity site for a measurement based on a second incubation time period, the second incubation time period being longer than the first incubation time period. Methods for incubating samples, e.g., methods which employ the systems of the present disclosure, are also provided. 1. An incubation system for incubating samples for an assay , the incubating system comprising:a rotary platform;a sample container comprising a sample positioned at a peripheral edge of the platform;a plurality of activity sites comprising at least a first and a second activity site;a processor; and rotate the rotary platform to move the sample container from the first activity site to the second activity site;', 'extract a first portion of the sample from the sample container at the first activity site for a measurement based on a first incubation time period; and', 'extract a second portion of the sample from the sample container at the second activity site for a measurement based on a second incubation time period, the second incubation time period being longer than the first incubation time period., 'a memory comprising instructions when executed by the processor cause the system to2. The incubating system of claim 1 , wherein the plurality of activity ...

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28-02-2019 дата публикации

METHOD OF DETERMINING PROTEIN EXPRESSION

Номер: US20190065673A1
Автор: Huang Ruo-Pan
Принадлежит:

Provided are embodiments of a method for determining a serum protein biomarker profile of a subject patient comprising: wicking blood from a subject onto a fluid sample collecting comb consisting of a absorbent strips, each absorbent strip consisting of a fibrous absorbent wick configured to absorb a predetermined volume of blood; drying the blood samples on the wicks and eluting serum proteins into an elution buffer; determining the identities and levels of the extracted proteins by microarray analysis; comparing by computer the identities and levels of the extracted proteins with a reference database generated from the blood samples from a plurality of subjects collected by a fluid sample collecting comb and producing a computer-generated report of the identities and levels of the biomarkers of the subject and adjusting the treatment based on the identities and amounts of the protein biomarkers of the blood sample of the subject. 113-. (canceled)14. A biological fluid sample collector comprising a sample collecting comb , said comb consisting of a plurality of absorbent strips , wherein each absorbent strip consists of a fibrous absorbent wick having a proximal end disposed between and adhering to a first holding strip and a second holding strip and a distal end extending from the holding strips , and wherein the plurality of fibrous absorbent strips is disposed between a first gripping sheet and a second gripping sheet and wherein the plurality of fibrous absorbent strips are attached to the first gripping sheet and optionally the second gripping sheet.15. The biological fluid sample collector of claim 14 , wherein the holding strips are attached to the fibrous absorbent wicks by an adhesive.16. The biological fluid sample collector of claim 14 , wherein the extended distal end of each fibrous absorbent strip is configured to absorb about 20 μl of a liquid.17. The biological fluid sample collector of further comprising a foldable cover extending from the first ...

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27-02-2020 дата публикации

PARTICLE SAMPLE PREPARATION WITH FILTRATION

Номер: US20200064240A1
Принадлежит:

A liquid transfer line receives a liquid having particles suspended therein and transfers the liquid to a capillary tube. A support tube secures the capillary tube therein. The support tube is substantially airtight except at a designated position. An optional securement secures the capillary tube within the support tube. A discharge end of the capillary tube is spaced from, and receded into, a discharge end of the support tube. A chuck is positioned below the support tube and is operable to open and to close to seal the designated position of the support tube. A sample substrate filters the liquid introduced through the liquid transfer line. Yet further, the sample preparation system comprises a pump that draws a vacuum that exhausts portions of the liquid that are not retained on the sample substrate. 1. A sample preparation system , comprising:a capillary tube having a discharge end; the liquid transfer line receives a liquid comprising suspended particles; and', 'transfers the received liquid to the capillary tube;, 'a liquid transfer line that terminates into the capillary tube, whereina support tube having a discharge end, the support tube positioned about the capillary tube such that the discharge end of the capillary tube is spaced from and receded into the discharge end of the support tube; the sample substrate receives the liquid discharged from the capillary tube;', 'the sample substrate filters the suspended particles from the liquid;, 'a sample substrate positionable adjacent to the support tube, whereina chuck interposed between a support member and the sample substrate, the chuck operable to open and close, thereby selectively creating a seal between the sample substrate and the support tube; anda pump that draws the liquid through the sample substrate.2. The sample preparation system according to claim 1 , wherein the capillary tube comprises an opening having a length and a width such that the width is orthogonal to the length claim 1 , and the ...

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09-03-2017 дата публикации

AUTOMATIC ASEPTIC SAMPLING VALVE FOR SAMPLING FROM ENCLOSED CONTAINERS

Номер: US20170067801A1
Принадлежит: Bend Research, Inc.

A sample can be collected from an enclosed container by opening a sample collection valve and drawing the sample from the enclosed container. After delivery of the sample out of a fluid flow path, a sanitizing fluid can be directed along the fluid flow path to sanitize the fluid flow path. 1. A fluid sampling system , comprising:a variable volume reservoir moveable between a first configuration that defines a first volume for receiving a fluid sample and a second configuration that defines a second volume, the first volume being larger than the second;a sample collection valve moveable between an open configuration and a closed configuration;a sample delivery flow path extending between at least the sample collection valve and the variable volume reservoir;a sanitizing fluid valve moveable between an open configuration and a closed configuration; anda sanitizing fluid flow path extending at least between the sanitizing fluid valve and the sample collection valve,wherein movement of the variable volume reservoir from the first configuration to the second configuration causes the fluid sample to be discharged from the variable volume reservoir.2. The fluid sampling system of claim 1 , wherein the variable volume reservoir comprises:a variable volume reservoir inlet through which the fluid sample is received into the variable volume reservoir; anda variable volume reservoir outlet through which the fluid sample is discharged from the variable volume reservoir.3. The fluid sampling system of claim 1 , wherein claim 1 , when the sample collection valve is in the closed configuration and the sanitizing fluid valve is in the open configuration claim 1 , the sanitizing fluid flow path extends at least from the sanitizing fluid valve to the sample collection valve and from the sample collection valve to the variable volume reservoir.4. The fluid sampling system of claim 1 , further comprising:a gas delivery valve moveable between an open configuration and a closed ...

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27-02-2020 дата публикации

Automatic sampling of hot phosphoric acid for the determination of chemical element concentrations and control of semiconductor processes

Номер: US20200066537A1
Принадлежит: Elemental Scientific Inc

Systems and methods for automatic sampling of a sample for the determination of chemical element concentrations and control of semiconductor processes are described. A system embodiment includes a remote sampling system configured to collect a sample of phosphoric acid at a first location, the remote sampling system including a remote valve having a holding loop coupled thereto; and an analysis system configured for positioning at a second location remote from the first location, the analysis system coupled to the remote valve via a transfer line, the analysis system including an analysis device configured to determine a concentration of one or more components of the sample of phosphoric acid and including a sample pump at the second location configured to introduce the sample from the holding loop into the transfer line for analysis by the analysis device.

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24-03-2022 дата публикации

Method and System for Sample Collection, Storage, Preparation and Detection

Номер: US20220088601A1
Принадлежит:

A collection device for a biological sample to capture target compounds such as viruses or other pathogens or particles for testing from within the sample and move the captured target compound to a separate chamber for subsequent processing. The collection device can include an openable substance blister including capture particles located in a cup interior. Capture particles can attract and bind the target compounds from the sample. An extraction tube extracts any nucleic acid from the target compound for storage or subsequent amplification and testing to confirm presence of known microorganisms. The extraction tube can comprise a heat-deformable material and can be connected to a microfluidic cartridge for further processing of nucleic acid including, amplification and detection. The microfluidic cartridge includes valves and a plurality of chambers for amplification. 1. A sample collection and processing device comprising:a cup having an opening configured for collecting a sample; attraction means for attracting the capture particles capturing at least a portion of the sample;', 'said attraction means moving said capture particles capturing at least a portion of the sample to an attachment tube, said attachment tube configured for attachment to a processing device., 'a substance comprising capture particles within an interior of said cup, the capture particles capturing at least a portion of the sample; and'}2. The sample collection and processing device according to wherein the substance is contained in an openable compartment within an interior of said cup and further comprising opening means for opening the openable compartment to release the substance claim 1 , the openable component is a blister claim 1 , the capture particles of the substance comprises magnetic capture beads claim 1 , upon opening of the openable compartment the magnetic capture beads capture and bind to the at least one portion of the sample and said attraction means is a magnet for ...

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24-03-2022 дата публикации

Plumbed in-line sensor system for swimming pools and spas

Номер: US20220089459A1
Принадлежит: ZODIAC POOL SYSTEMS LLC

A sensor system for swimming pools and spas is detailed herein. The sensor system can include one or more sensors positioned in a sensor housing located within a cavity of a pipe and in-line with an inlet and an outlet of the pipe. The sensor housing can divert a portion of water flowing through the cavity to an interior of the sensor housing and to an area around the sensors and maintain at least some of the diverted water in the area around the sensors even if the water is not flowing through or is drained from the pipe.

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05-03-2020 дата публикации

Systems And Methods For Simultaneous Detection And Identification Of Microorganisms Within A Fluid Sample

Номер: US20200070146A1
Автор: Tomaras Andrew
Принадлежит:

An optical measurement instrument is an integrated instrument that includes an optical cavity with a light source, a sample cuvette, and an optical sensor. The light source and sensor are on a bench that is on a translational or rotational mechanical platform such that optical beam can be moved to multiple sample containers. Each sample containers holds a distinct microorganism-attracting substance and a portion of a fluid sample containing an unknown microorganism. Each distinct microorganism-attracting substance is configured to bind with a single type of microorganism. The unknown microorganism in the fluid sample binds with the distinct microorganism-attracting substance in a single sample container. The instrument incubates the microorganism in the single sample container and detects the presence of the microorganism in the single sample container to thereby simultaneously identify the unknown microorganism. 1. A specimen collection device , comprising:an inlet; anda plurality of fluid containers in fluid communication with the inlet, each of the plurality of fluid containers including a distinct microorganism-attracting substance disposed therein, the distinct microorganism-attracting substance of each of the plurality of fluid containers being configured to attract a respective one of a plurality of types of microorganisms such that each of the plurality of fluid containers is associated with the respective one of the plurality of types of microorganisms.2. The specimen collection device of claim 1 , wherein each of the microorganism-attracting substances includes an affinity body coupled to one or more molecules of respective one of a plurality of types of binding partners claim 1 , the respective one of the plurality of types of binding partners of each distinct microorganism-attracting substance being configured to bind with the respective one of the plurality of types of microorganisms.3. The specimen collection device of claim 2 , wherein the affinity ...

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17-03-2016 дата публикации

METHODS FOR SAMPLING FROM NON-ATMOSPHERIC VESSELS IN A PARALLEL REACTOR SYSTEM

Номер: US20160076977A1
Принадлежит:

Methods for sampling reactor contents in parallel reactor systems are disclosed. The methods may be used to sample reactor contents in non-atmospheric (e.g., pressurized) reaction vessels. 1. A method for sampling a non-atmospheric reaction vessel of a parallel reactor system , the reactor system including a reactor array comprising at least two reaction vessels , antechambers disposed above each reaction vessel , antechamber sealing members , a port valve disposed between each antechamber and each reaction vessel and a sampling system for sampling material from the reaction vessels , the sampling system comprising a sampling pump , a sampling needle having a tip , and a sampling valve disposed between the sampling pump and tip , the method comprising:lowering the sampling needle into an antechamber to form a substantially fluid-tight seal between the antechamber sealing member and the sampling needle;lowering the sampling needle into the reaction vessel, the vessel having reactor material therein;introducing material from the reaction vessel into the sampling needle to form a sampling slug;raising the sampling needle to position the tip of the sampling needle in the antechamber;closing the port valve after the tip of the sampling needle is positioned in the antechamber;retracting the slug so that a first portion is disposed between the sampling valve and the sampling pump and a second portion is disposed between the sampling valve and the tip of the sampling needle; anddischarging the slug into a target substrate.2. The method as set forth in further comprising depressurizing the antechamber after retracting the slug.3. The method as set forth in or wherein the second portion of material disposed between the sampling valve and the tip of the sampling needle upon retracting the slug is suspended in the sampling system by surface tension.4. The method as set forth in wherein the reactor array comprises 2 reaction vessels or more or 4 reaction vessels or more claim 1 ...

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07-03-2019 дата публикации

SAMPLE PREPARING APPARATUS, SAMPLE PREPARING SYSTEM, SAMPLE PREPARING METHOD, AND PARTICLE ANALYZER

Номер: US20190072578A1
Автор: BUSCHKE David
Принадлежит:

To accurately analyze measurement target particles in each specimen, while reducing variation in dispensing amounts of specimens which is caused by different viscosities of the respective specimens. A sample preparing apparatus includes: a measurement section configured to measure a specimen obtained from a specimen container and obtain viscosity information relating to viscosity of the specimen; a sample preparation section configured to prepare a measurement sample by aspirating the specimen from the specimen container discharging the specimen into a mixing container and mixing the specimen with a labeling substance in the mixing container and a control section configured to determine, on the basis of viscosity information, at least one of an aspiration condition for aspirating the specimen and a discharge condition for discharging the specimen, and control the sample preparation section 1. A sample preparing apparatus comprising:a sample preparation section configured to prepare a measurement sample by dispensing a specimen from a specimen container into a mixing container, and mixing the specimen with a reagent in the mixing container; anda control section configured to control the sample preparation section to dispense the specimen into the mixing container in accordance with a dispensing condition based on a viscosity of the specimen.2. The sample preparing apparatus of claim 1 , further comprising a measurement section configured to measure the specimen to obtain viscosity information relating to the viscosity of the specimen claim 1 , whereinthe control section controls the sample preparation section to dispense the specimen into the mixing container in accordance with a dispensing condition based on the viscosity information.3. The sample preparing apparatus of claim 1 , wherein the reagent contains a labeling substance.4. The sample preparing apparatus of claim 1 , wherein the control section determines the dispensing condition so that an amount of the ...

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05-03-2020 дата публикации

MODULAR SYSTEM FOR UPSTREAM WASTEWATER SAMPLING

Номер: US20200072709A1
Принадлежит:

A wastewater sampling system including: an inlet tube; an outlet port; a high-flow circuit fluidly coupling the inlet tube to the outlet port; a first pump, along the high-flow circuit, configured to pump wastewater through the high flow circuit; a sampling circuit, fluidly coupled to the high-flow circuit via a junction, comprising a solid waste filter fluidly coupled to the junction and a solid-phase extraction cartridge fluidly coupled to an outlet of the solid waste filter; a second pump along the sampling circuit; a controller configured to, during a sampling cycle at a first time, activate the first pump; at a second time, activate the second pump; and at a third time succeeding the second time by a sampling duration, deactivate the second pump. 1. A wastewater sampling system comprising:an inlet tube configured to extend into a sewage flow;an outlet port;a high-flow circuit fluidly coupling the inlet tube to the outlet port;a first pump positioned along the high-flow circuit and configured to pump wastewater from the sewage flow, through the inlet tube, and out of the outlet port; a solid waste filter fluidly coupled to the junction; and', 'a solid-phase extraction cartridge fluidly coupled to an outlet of the solid waste filter;, 'a sampling circuit fluidly coupled to the high-flow circuit via a junction and comprisinga second pump positioned along the sampling circuit; and at a first time, activate the first pump to initiate flow of wastewater from the sewage flow through the high-flow circuit;', 'at a second time, activate the second pump to divert wastewater from the high-flow circuit into the sampling circuit via the junction; and', 'at a third time succeeding the second time by a sampling duration, deactivate the second pump., 'a controller configured to, during a sampling cycle2. The wastewater sampling system of further comprising an external casing suspended above a sewage flow at a sewage access point claim 1 , the external casing housing:the high- ...

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05-03-2020 дата публикации

IN-SITU MEASUREMENT OF NITRATE IN SOIL

Номер: US20200072737A1
Принадлежит:

A system for measuring with the aid of light absorption spectrometry the concentration of one or more analytes in porewater in soil, the system comprising: one or more monitoring unit(s), each monitoring unit comprising a porewater sampler (), an optical flow cell () with a tube connecting the liquid inlet port of said optical flow cell to said porewater sampler; and vacuum arrangement to enable extraction of porewater; at least one light source () for generating a light beam to be transmitted through said optical flow cell (); and at least one detector () for obtaining spectral information from the beam exiting said optical flow cell. A method of measurement is also provided. 1) A system for measuring with the aid of light absorption spectrometry the concentration of one or more analytes in porewater in soil , the system comprising:one or more monitoring unit(s), each monitoring unit comprising a porewater sampler, an optical flow cell with a tube connecting the liquid inlet port of said optical flow cell to said porewater sampler; and vacuum arrangement to enable extraction of porewater;at least one light source for generating a light beam to be transmitted through said optical flow cell; andat least one detector for obtaining spectral information from the beam exiting said optical flow cell.2) A system according to claim 1 , comprising:one or more monitoring unit(s), each monitoring unit consisting of a porewater sampler, an optical flow cell and a sampling cell, with tubes connecting the liquid inlet and outlet ports of said optical flow cell to said porewater sampler and sampling cell, respectively;a vacuum generating device to enable extraction of porewater;at least one light source for generating a light beam to be transmitted through said optical flow cell; andat least one detector for obtaining spectral information from the beam exiting said optical flow cell.3) A system according to claim 1 , comprising an array of individual monitoring units installed at ...

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18-03-2021 дата публикации

Device for surface sampling

Номер: US20210080356A1
Автор: Lennart Sjölén
Принадлежит: Expertus Kemiteknik Ab

Device (1) for surface sampling, comprising: a flat material layer (2) comprising a surface portion (2c) and a circumferential edge portion (2d) defining the boundary of the surface portion (2c), further comprising a sampling volume (2a), wherein the sampling volume (2a) is adapted to comprise a filler device (2b) for filling out the sampling volume (2a), a protective layer (3) arranged on the surface portion (2c) of the material layer (2) by an adhesive (4) arranged on the material layer (2), wherein a portion (3a) of the protective layer (3) extends beyond the boundary of the surface portion (2c) for facilitating a removal of the protective layer (3) from the material layer (2).

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26-03-2015 дата публикации

DEVICE FOR SAMPLING FLUID UNDER PRESSURE FOR GEOLOGICAL SITE DEVELOPMENT MONITORING

Номер: US20150083403A1
Принадлежит:

The invention relates to a fluid sampling device comprising a sample chamber () including a lower piston (), an upper piston () and an intermediate piston (). Intermediate piston () is moved so as to guarantee a substantially constant volume for chamber () when closing the chamber. 1) A device for sampling at least one fluid under pressure , comprising a sample chamber defining an inner volume intended to receive said fluid , characterized in that said device comprises a lower piston arranged in the lower part of said chamber , an upper piston arranged in the upper part of said chamber , an intermediate piston arranged between said lower and upper pistons , means for closing and opening said chamber by moving said lower piston , and means for moving said intermediate piston allowing to define a substantially constant volume for said chamber upon closing of said chamber.2) A device as claimed in claim 1 , wherein the volume of said chamber is defined by said intermediate piston and said lower piston.3) A device as claimed in claim 2 , wherein said intermediate piston is arranged at a substantially constant distance from said lower piston in open position and in closed position of said chamber claim 2 , said intermediate piston resting against said upper piston when said chamber is in closed position.4) A device as claimed in claim 2 , wherein said device comprises means for transferring the fluid out of the chamber claim 2 , said transfer means comprising means for controlling the joint descent of said upper piston and of said intermediate piston from the upper part to the lower part of said chamber.5) A device as claimed in claim 1 , wherein the volume of said chamber is defined by said by said intermediate piston and said upper piston.6) A device as claimed in claim 5 , wherein said intermediate piston is arranged at a substantially constant distance from said upper piston in open position and in closed position of said chamber claim 5 , said intermediate piston ...

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22-03-2018 дата публикации

Materials Transport Device for Diagnostic and Tissue Engineering Applications

Номер: US20180078932A1
Принадлежит:

Devices that can transport biological materials are described. The devices incorporate capillary channeled fibers that can effectively transport living cells as well as other biological materials such as nutrients, growth factors, waste materials, etc. The devices can include a sorptive material at one end of the fibers that can improve transport of materials through the devices. The devices can differentially transport different cell types, particularly when the fibers are held in a vertical orientation. Diagnostic devices that incorporate the capillary channeled fibers are described that can be utilized to separate cell types from one another. Tissue engineering scaffolds that incorporate the capillary channeled fibers are described that can more efficiently transport materials into and out of the scaffolds. 1. A device for transporting biological materials comprising:a plurality of capillary channeled fibers, each capillary channeled fiber having a longitudinal axis along a length of the fiber, an outer surface, and a non-circular cross section that is perpendicular to the longitudinal axis of the fiber, each capillary channeled fiber including a plurality of co-linear open-topped channels extending along the entire length of the fiber, each open-topped channel being open at the outer surface of the fiber, each open-topped channel being defined by two opposed walls, each wall extending in a first direction that is along the length of and parallel to the longitudinal axis of the fiber and each wall also extending in a second direction that is perpendicular to the longitudinal axis of the fiber, with each wall forming a side wall of one channel and each wall forming a part of the exterior surface of an open-topped fiber, the plurality of capillary channeled fibers being held adjacent to one another and generally aligned with one another in a bundle such that at least one closed channel is formed between a first open-topped channel of a first fiber and a second open ...

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31-03-2022 дата публикации

METHOD AND ARRANGEMENT FOR FEEDBACK BASED CONTROL IN CHEMICAL REFINING OF WOOD

Номер: US20220097252A1
Принадлежит:

Method and control system are provided for controlling values of process parameters of a pretreatment process of wood particles. A sampler is used to obtain a sample of a product flow of said pretreatment process after said wood particles have undergone steam explosion in a hemihydrolysis reactor. A particle measurement device is used to measure one or more characteristics of particles in said sample and to produce one or more pieces of measurement information indicative of the measured characteristics. Said one or more pieces of measurement information are used to select one or more values of one or more of said process parameters. 1. A method for controlling values of process parameters of a pretreatment process of wood particles , the method comprising:using a sampler to obtain a sample of a product flow of said pretreatment process after said wood particles have undergone steam explosion in a hemihydrolysis reactor;using a particle measurement device to measure one or more characteristics of particles in said sample and to produce one or more pieces of measurement information indicative of the measured characteristics; andusing said one or more pieces of measurement information to select one or more values of one or more of said process parameters;wherein said using of said one or more pieces of measurement information to select one or more values of said one or more of said process parameters comprises selecting at least a value of a second residence time of said product flow in an impregnating vessel that precedes said hemihydrolysis reactor in said pretreatment.2. The method according to claim 1 , wherein said one or more of said process parameters comprise at least one of:a temperature in said hemihydrolysis reactor,a pressure difference between an input and output of said hemihydrolysis reactor, anda first residence time of said product flow in said hemihydrolysis reactor.3. The method according to claim 2 , wherein:said particle measurement device is ...

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23-03-2017 дата публикации

Post-Probe Upstream Metering Pump for Insuring NGL Phase Change Completion in Sample Conditioning

Номер: US20170082524A1
Автор: Curtis Micah A.
Принадлежит: MUSTANG SAMPLING LLC

A post-probe upstream metering pump for insuring phase change completion of a multi-phase fluid such as Natural Gas Liquid (NGL) in a sample conditioning system having a pipeline sample take-off probe for fluid extraction, a sample conditioning unit for conditioning the extracted fluid to a select range of temperature and pressure for analysis of the fluid sample by an associated analyzer without dew point dropout or phase separation, and a metering pump disposed in-line between the sample take-off probe and the sample conditioning unit to pressurize the fluid sample to condense into a substantially fully liquid phase and to reduce lag time between extraction and fluid sample conditioning. 1. A system for multi-phase fluid sample extraction , comprising:a) a sample take-off probe for extracting multi-phase fluid from a pipeline;b) a sample conditioning unit for vaporizing the extracted fluid sample and maintaining the vaporized sample in select temperature and pressure ranges to prevent dew point dropout and passing the conditioned vaporized sample to a downstream analyzer; andc) a metering pump disposed in-line between the sample take-off probe and the sample conditioning unit to increase pressure on and condense the extracted fluid sample to maximize transition of the multi-phase fluid sample into a single fully liquid phase.2. The system of further comprising a particulate coalescing filter disposed in-line between the sample take-off probe and the metering pump.3. The system of where the metering pump is a pneumatic pump.4. The system of where the pneumatic pump includes a pneumatic controller and an air isolation valve.5. The system of where the pneumatic controller includes at least one feedback sensor.6. The system of where the multi-phase fluid is natural gas liquid and further including a speed loop return to the pipeline.7. The system of where the metering pump generates a pressure of at least 400 PSIG.8. The system of where the metering pump generates ...

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31-03-2022 дата публикации

LIQUID TRANSFER DEVICE

Номер: US20220099471A1
Принадлежит:

A device for transferring liquids and liquid samples in certain quantities includes a first housing, a second housing, and a liquid extraction assembly. The first housing includes a first sidewall, a first top wall, an extrusion portion, and a first receiving cavity. The extrusion portion is disposed in the first receiving cavity. The second housing includes a second sidewall, a second top wall, and a second receiving cavity. The first housing is received in the second receiving cavity. The liquid extraction assembly includes a liquid extraction pipe and a liquid extraction head. By thumb or finger pressure, the first housing can be moved into the second receiving cavity to compress the extrusion portion to cause release of a sample, or released to gather a sample. 1. A liquid transfer device , comprising:a first housing;a second housing; anda liquid extraction assembly;wherein the first housing comprises a first sidewall, a first top wall, and an extrusion portion, the first sidewall is connected to the first top wall, the first sidewall and the first top wall cooperatively define a first receiving cavity, the extrusion portion is disposed on the first top wall and received in the first receiving cavity, the second housing comprises a second sidewall and a second top wall, the second sidewall is connected to the second top wall, the second sidewall and the second top wall cooperatively define a second receiving cavity, the first housing is received in the second receiving cavity;wherein the liquid extraction assembly comprises a liquid extraction pipe and a liquid extraction head connected to the liquid extraction pipe, the liquid extraction pipe is disposed between the first top wall and the second top wall and corresponds to the extrusion portion, the liquid extraction head extends out of the second top wall, the extrusion portion is configured to squeeze the liquid extraction pipe, the first housing is configured to move back and forth along a central axis of ...

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31-03-2022 дата публикации

PROCESS WATER ANALYSIS SAMPLING ARRANGEMENT

Номер: US20220099537A1
Принадлежит: HACH LANGE GMBH

A process water analysis sampling assembly includes an immersion probe having a first filter unit and a second filter unit which are fluidically separated from each other, a flushing liquid tank, and a fluidics control. The fluidics control includes a pump arrangement which is fluidically connected to each of the first filter unit and the second filter unit, at least two liquid pumps which are arranged to be mutually independent from each other, and a valve arrangement having plurality of switchable valves. The fluidics control controls a sampling and a flushing of the immersion probe. The fluidic control fluidically connects the flushing liquid tank to one of the first filter unit and the second filter unit and simultaneously connects an analysis unit to the other one of the first filter unit and the second filter unit. 1. A process water analysis sampling assembly comprising:an immersion probe comprising a first filter unit and a second filter unit which are fluidically separated from each other;a flushing liquid tank; and{'claim-text': ['a pump arrangement which is fluidically connected to each of the first filter unit and the second filter unit,', 'at least two liquid pumps which are arranged to be mutually independent from each other, and', 'a valve arrangement which comprises a plurality of switchable valves,'], '#text': 'a fluidics control comprising,'}{'claim-text': ['to control a sampling and a flushing of the immersion probe,', 'so that the flushing liquid tank is fluidically connected to one of the first filter unit and the second filter unit, and', 'so that an analysis unit is simultaneously connected to the other one of the first filter unit and the second filter unit.'], '#text': 'the fluidics control being configured,'}2. The process water analysis sampling arrangement as recited in claim 1 , further comprising:a cleaning gas pump which is configured to pump a cleaning gas,wherein{'claim-text': ['a first cleaning gas outlet which is arranged at a ...

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31-03-2022 дата публикации

Hazardous contaminant collection kit and rapid testing

Номер: US20220099648A1
Принадлежит: Becton Dickinson and Co

Contamination detection systems, kits, and techniques are described for testing surfaces for the presence of hazardous contaminants, while minimizing user exposure to these contaminants. Even trace amounts of contaminants can be detected. A collection kit provides a swab that is simple to use, easy to hold and grip, allows the user to swab large areas of a surface, and keeps the user's hands away from the surface being tested. The kit also provides open and closed fluid transfer mechanism to transfer the collected fluid to a detection device while minimizing user exposure to hazardous contaminants in the collected fluid. Contamination detection kits can rapidly collect and detect hazardous drugs, including trace amounts of antineoplastic agents, in healthcare settings at the site of contamination.

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19-06-2014 дата публикации

Gradually-Ascending Spiraled Passive Sampler for Measuring Sediment-Water Diffusion Flux of Organic Pollutants

Номер: US20140165712A1

The present invention discloses a gradually-ascending spiraled passive sampler for measuring sediment-water diffusion flux of organic polutants, which comprises a sediment pore-water sampler and a water sampler arranged above the sediment pore-water sampler, wherein a plurality of sediment sampling units are vertically arranged in the sediment pore-water sampler, and the water sampler is provided with a plurality of water sampling units arranged transversely along the vertical direction in sequence.

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29-03-2018 дата публикации

ACTIVELY SHAKEN IN-SITU PASSIVE SAMPLING DEVICE

Номер: US20180088008A1
Принадлежит:

A vibrating platform for the deploying of passive sampling devices in sediments and other media to be sampled. The vibrating platform can greatly enhance the rate of mass transfer of analytes, such as polycyclic aromatic hydrocarbons and polychlorinated biphenyls, into passive sampler material by disrupting the formation of a depletion layer in proximity of the passive sampler material. 1. A passive sampling device (PSD) comprising at least one cage and at least one vibrating device , wherein at least one passive sampler is in each cage.2. The PSD of claim 1 , wherein the at least one cage is in direct contact with the at least one vibrating device.3. The PSD of claim 1 , further comprising at least one pulse-pause timer.4. The PSD of claim 1 , wherein the at least one cage can comprise a pocket which the passive sampler can be inserted into.5. The PSD of claim 1 , wherein the cage comprises metal claim 1 , polymer claim 1 , or a combination thereof claim 1 , and is substantially resistant to corrosion in claim 1 , and is durable enough to be placed in claim 1 , an environment to be tested.6. The PSD of claim 5 , wherein the cage comprises copper claim 5 , stainless steel claim 5 , or alloys comprising copper claim 5 , nickel claim 5 , and/or chromium.7. The PSD of claim 1 , wherein the cage is open to the environment for the flow of analyte into and out of the cage.8. The PSD of claim 1 , wherein at least one passive sampler comprises a material selected from the group consisting of silicone rubber claim 1 , low-density polyethylene (LDPE) claim 1 , polyethylene (PE) claim 1 , polyoxymethylene (POM) claim 1 , polydimethylsiloxane (PDMS) claim 1 , polyethersulfone (PES) claim 1 , and polyacrylate (PA) claim 1 , optionally impregnated with a performance reference compound.9. A method of determining the amount of an analyte in an environment claim 1 , said method comprising:(a) positioning a PSD in the environment for time x, wherein the PSD comprises at least one ...

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21-03-2019 дата публикации

LIQUID DISPENSER WITH MANIFOLD MOUNT FOR MODULAR INDEPENDENTLY-ACTUATED PIPETTE CHANNELS

Номер: US20190086436A1
Принадлежит:

Automated pipetting systems and methods are disclosed for aspirating and dispensing fluids, particularly biological samples. In one aspect, a liquid dispenser includes a manifold and one or more pipette channels. The manifold includes a vacuum channel, a pressure channel, and a plurality of lanes. Each lane includes an electrical connector, a port to the pressure channel, and a port to the vacuum channel. The pipette channels can be modular. Each pipette channel includes a single dispense head and can be selectively and independently coupled to any one lane of the plurality of lanes. In some aspects, a valve in the pipette channel is in simultaneous fluid communication with a pressure port and a vacuum port of the manifold. The valve selectively diverts gas under pressure and gas under vacuum to the dispense head in response to control signals received through the electrical connector of the manifold. 188-. (canceled)89. A liquid dispenser comprising:a manifold comprising a vacuum channel, a pressure channel, and a plurality of lanes, each lane comprising an electrical connector, a port to the pressure channel, and a port to the vacuum channel;one or more pipette channels, each pipette channel comprising a single dispense head and configured to couple to the electrical connector, the pressure port, and the vacuum port of any one lane of the plurality of lanes; andwherein each pipette channel comprises a first portion that does not move relative to the manifold when the pipette channel is coupled to the manifold and a second portion that moves relative to the manifold when the pipette channel is coupled to the manifold,wherein a valve is enclosed within the first portion of each pipette channel, the dispense head is coupled to the second portion, and a tube connecting the valve and the dispense head is configured to move within the first portion when the second portion moves relative to the first portion.90. The liquid dispenser of claim 89 , wherein the valve is ...

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19-03-2020 дата публикации

METHODS AND DEVICES FOR SAMPLE CAPTURE USING GAS-PULSE NANOPARTICLE DISPLACEMENT

Номер: US20200088608A1
Принадлежит:

The present disclosure provides for sampling instruments and methods of collecting sample particles. The sampling instrument can include a high-pressure pulsed valve coupled to a gas flow system to displace a sample from a surface. Also included can be a voltage supply coupled to a voltage switch, a suction device, a sample collector, and a collection filter. To collect a sample, extractive particles can be deposited onto a sample present on a substrate. At least a portion of the sample becomes coupled to a portion of the extractive particles to form sample particles. High-pressure gas can be discharged at the sample, thereby aerosolizing a portion of the sample particles to disperse aerosolized sample particles. A portion of the aerosolized sample particles can be collected onto a collection filter to form a collected sample. 1. A sampling instrument , comprising:a high-pressure pulsed valve coupled to a gas flow system to displace a sample from a surface;a voltage supply coupled to a high voltage switch;a suction device;a sample collector; anda collection filter.2. The sampling instrument of claim 1 , wherein the sampling instrument is portable.3. The sampling instrument of claim 1 , wherein the gas flow system comprises a high-pressure gas dispenser.4. The sampling instrument of claim 3 , wherein the high-pressure gas dispenser is selected from a COcartridge or a refillable gas cylinder.5. The sampling instrument of claim 1 , wherein gas from the gas flow system is dispensed at a pressure of about 10 PSIG to about 100 PSIG.6. The sampling instrument of claim 1 , wherein the sample collector comprises a tube or a syringe.7. The sampling instrument of claim 1 , the high-pressure pulsed valve is operated by a battery.8. The sampling instrument of claim 1 , wherein the high-pressure pulsed valve operates at a pressure of about 10 psi to about 100 psi and a pulse repetition rate from single shot to about 100 Hz.9. The sampling instrument of claim 1 , further ...

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01-04-2021 дата публикации

SYSTEM AND DEVICES FOR MONITORING CELL-CONTAINING MATERIALS AND METHODS OF THEIR USE

Номер: US20210096094A1
Принадлежит:

The present application is directed to a system for collecting or extruding a cell-containing biological material. The system includes an extrusion/collection device comprising: an orifice and a chamber operably connected to the orifice and an electrical impedance spectroscopy (EIS) device, operably connected to the extrusion/collection device. The EIS device monitors biologically relevant attributes of a cell-containing biological material as it is extruded from or collected into the extrusion/collection device. Also disclosed are methods of using the system disclosed herein. 1. A system for collecting or extruding a cell-containing biological material , said system comprising: an orifice and', 'a chamber operably connected to the orifice and, 'an extrusion/collection device comprisingan electrical impedance spectroscopy (EIS) device, operably connected to the extrusion/collection device, wherein the EIS device monitors biologically relevant attributes of a cell-containing biological material as it is extruded from or collected into the extrusion/collection device.2. The system according to claim 1 , wherein the extrusion/collection device is a syringe.3. The system according to claim 2 , wherein the extrusion/collection device further comprises a fitting for connecting a cannula to the syringe.4. The system according to claim 3 , wherein the fitting is a Luer taper fitting.5. The system according to claim 3 , wherein the fitting comprises a passage through which the cell-containing biological material passes when it is extruded from or collected into the extrusion/collection device.6. The system according to claim 5 , wherein the fitting comprises anti-parallel electrodes positioned in the passage to create an electrical field for detecting impedance of the cell-containing biological material.7. The system according to further comprising: receive one or more of the biologically relevant attributes of the cell-containing biological material from the EIS device; and ...

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16-04-2015 дата публикации

Fixed Chamber Separator With Adjustment Withdrawal Member

Номер: US20150104824A1
Принадлежит:

A separation device that can include a separation tube or container that has a wall defining an internal volume into which a material can be placed is disclosed. The material can include a multi-component mixture or solution. A secondary tube or withdrawal cannula can be placed and/or moved within the tube to withdrawal a material form the tube. 1. A system to access at least one component of a multiple component material , comprising:a separation container configured to receive the multiple component material including a sidewall extending from a first end to a second end, the sidewall having an internal surface;a first internal extension wall portion extending towards a central axis of the separation container; anda withdrawal member moveable within the container and configured to interact with the first internal extension wall to assist in removing at least one component of the multiple component material from the separation container;wherein the withdrawal member is moveable between a first position and a second position within the separation container and relative to the first internal extension wall.2. The system of claim 1 , wherein the first internal extension wall portion is angled towards the second end of the separation container.3. The system of claim 1 , wherein the first internal extension wall portion includes a first section and a second section claim 1 , wherein the first section is angled at a first angle towards the second end and the second section is angled at a second angle towards the first end of the container;wherein the withdrawal member is configured to move from the first position to access a component at the first section to the second position to access a second component at the second section.4. The system of claim 3 , wherein the withdrawal member includes:an elongated portion having a withdrawal bore formed therethrough; andan distal portion having a sealing portion at an end of the elongated portion and at least one port formed ...

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13-04-2017 дата публикации

ACTUATION DEVICE FOR A PISTON OF A SYRINGE

Номер: US20170102403A1
Принадлежит: CTC Analytics AG

The present application relates to an actuation device for a piston of a syringe. The actuation device comprises a holder for a barrel of the syringe, a coupling which is linearly movable relative to the holder and has a seat into which the piston of the syringe can be inserted, at least one securing element with which the piston can be secured releasably in the seat, and a linear drive for the coupling. The coupling has at least two electrically conductive contact elements which are arranged inside the seat in order to come into contact with corresponding electrically conductive contact faces of the piston when the piston is inserted into the seat. The present application further relates to a sampling system with an actuation device and with at least one syringe, and also to a syringe suitable for the sampling system. 114-. canceled15. An actuation device for a piston of a syringe , comprising a holder for a barrel of the syringe , a coupling which is linearly movable relative to the holder and has a seat into which the piston of the syringe can be inserted , at least one securing element with which the piston can be secured releasably in the seat , and a linear drive for the coupling , wherein the coupling has at least two electrically conductive contact elements which are arranged inside the seat in order to come into contact with corresponding electrically conductive contact faces of the piston when the piston is inserted into the seat.16. The actuation device according to claim 15 , wherein an inner wall of the seat is designed as a first contact element of the at least two contact elements.17. The actuation device according to claim 15 , wherein a first contact element of the at least two contact elements is designed as a round face claim 15 , and the at least one further contact element is designed as a circle concentric to the round face.18. The actuation device according to claim 15 , wherein the at least two contact elements are prestressed inside the seat ...

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19-04-2018 дата публикации

Media suction devices and methods

Номер: US20180105785A1
Принадлежит: Janssen Biotech Inc

Devices and methods are provided for removing media from a culture vessel that decreases disruption of the interface between the cellular material and media within the vessel such that aspiration and removal of cells or cell clusters along with the media is minimized. In addition, the media fluid turbulence is decreased so as to minimize the activation or disruption of cells and cell clusters.

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11-04-2019 дата публикации

Improved apparatus and method for sampling fluids without volume limitation

Номер: US20190107468A1
Автор: Mohammad Ghadyani
Принадлежит: Individual

An improved apparatus and method for sampling fluids without volume limitation comprises, in one implementation, a holder unit, a pumping unit, and a control unit. The pumping unit includes an inlet channel, an outlet channel, a pumping motor, and a circulation hose in which the pumping motor is configured to circulate a fluid specimen from the inlet channel to the outlet channel into the circulation hose. The circulation hose is attached to the outlet channel, and secured to the holder unit displaced from a user to prevent direct contact with the fluid specimen during sampling when dealing with a hazardous specimen. The control unit includes a switch, a regulating module, and an electronic board, and is configured to regulate circulation of the fluid specimen through the pumping unit. The switch is configured to START/END the sampling process and to send signals to the electronic board to stay ON/OFF during sampling, and the regulating module is configured to adjust voltage of the pumping motor consistent with viscosity of the fluid specimen to allow circulation without volume limitation.

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28-04-2016 дата публикации

Emission monitoring system for a venting system of a nuclear power plant and nuclear power plant having the emission monitoring system

Номер: US20160118149A1
Автор: Axel Hill
Принадлежит: AREVA GMBH

An emission monitoring system for a venting system of a nuclear power plant is configured for low consumption of energy while having high reliability of measurement results. The emission monitoring system has a pressure relief line connected to a containment and contains a high-pressure section, a low-pressure section, and a sampling line, which, on the inlet side, opens into the low-pressure section of the pressure relief line and is guided from there to a functional path through which steam flows. An ejector containing a pump fluid connector, a suction connector and an outlet connector is provided. A pump fluid feed line has an inlet side opening into the high-pressure section of the pressure relief line and is guided from there to the ejector and connected to the pump fluid connector. A sample return line is guided from the functional path to the ejector and connected to the suction connector.

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09-06-2022 дата публикации

MICROSCOPIC OBJECT COLLECTION SYSTEM AND MICROSCOPIC OBJECT COLLECTION METHOD

Номер: US20220178798A1
Принадлежит:

A laser module includes a plurality of light emission regions and the plurality of light emission regions emit a plurality of laser beams. An optical waveguide and a lens condense the plurality of laser beams to an identical focal point. An adjustment mechanism is configured to adjust relative positional relation between the sample stage and a condenser lens (the optical waveguide and the lens). A controller is configured to switch between a single-point irradiation mode and a multi-point irradiation mode. The single-point irradiation mode refers to a mode in which the adjustment mechanism is controlled such that the focal point of the plurality of laser beams falls on the thin film. The multi-point irradiation mode refers to a mode in which the adjustment mechanism is controlled such that the focal point does not fall on the thin film. 1: A microscopic object collection system that collects a plurality of microscopic objects dispersed in a liquid , the microscopic object collection system comprising:a holder configured to hold a substrate provided with a photothermal conversion region;a laser beam source including a plurality of light emission regions, the plurality of light emission regions emitting a plurality of laser beams;a condenser lens that condenses the plurality of laser beams to an identical focal point;an adjustment mechanism configured to adjust relative positional relation between the holder and the condenser lens; anda controller that controls the adjustment mechanism, whereinthe controller is configured to switch between a single-point irradiation mode and a multi-point irradiation mode, the single-point irradiation mode and the multi-point irradiation mode each being a mode for irradiating the photothermal conversion region with at least one of the plurality of laser beams,the single-point irradiation mode is a mode in which the adjustment mechanism is controlled such that the focal point of the plurality of laser beams falls on the photothermal ...

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13-05-2021 дата публикации

FIELD FLOW FRACTIONATION DEVICE

Номер: US20210138482A1
Принадлежит: SHIMADZU CORPORATION

A field-flow fractionation device includes a separation channel, a carrier fluid supplier, a separation membrane, a waste liquid chamber, a cross-flow flow rate adjuster, and a carrier fluid adder. The carrier fluid adder is configured to add, to a flow of a carrier fluid having passed through the separation membrane, a flow of another carrier fluid at a carrier fluid adding position set on an upstream side of the cross-flow flow rate adjuster so that the flow rate of the carrier fluid flowing into the cross-flow flow rate adjuster is larger than the flow rate of the carrier fluid having passed through the separation membrane. 1. A field-flow fractionation device comprising:a separation channel provided with an inlet port and an outlet port at both ends thereof, the channel forming a space through which a carrier fluid is to flow;a carrier fluid supplier which supplies the carrier fluid to the separation channel via the inlet port;a separation membrane which blocks particles to be separated from passing therethrough while passing the carrier fluid therethrough, the membrane forming a wall surface defining the separation channel;a waste liquid chamber which forms a space in which the carrier fluid having passed in the separation channel through the separation membrane flows, the waste liquid chamber having a discharge port for discharging the carrier fluid having passed through the separation membrane to the outside;a cross-flow flow rate adjuster connected to the discharge port, the cross-flow flow rate adjuster configured to adjust a flow rate of a cross flow formed by the carrier fluid passing through the separation membrane from the separation channel by adjusting a flow rate of the carrier fluid discharged from the waste liquid chamber via the discharge port to a preset flow rate; anda carrier fluid adder which adds another flow of the carrier fluid to a flow of the carrier fluid having passed through the separation membrane at a carrier fluid adding position ...

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27-04-2017 дата публикации

Fluid Sampling

Номер: US20170115190A1
Автор: Jim Hall, Sven Lataire
Принадлежит: SGS North America Inc

A fluid sampling device having a first conduit configured to couple an outlet of a fluid source to a sample inlet port; a second conduit configured to couple a sample outlet port to an inlet of the fluid source; an expansion chamber including an inlet and an outlet coupled to the first and second conduits by a valve assembly; and a pressure relief valve configured to couple the outlet of the expansion chamber to the inlet of the fluid source. The fluid sampling device facilitates acquisition of a fluid sample and subsequent purging of its internal components while inhibiting the release of sample fluid to the surrounding environment, thereby protecting the environment and sampling personnel from harmful chemical release. The fluid sampling device may facilitate a sample acquisition process that provides closed-loop flush and expansion operations for obtaining a representative sample at the appropriate fill density of the sample vessel.

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03-05-2018 дата публикации

Microorganism sampling method, microorganism sampling device and sampling kit comprising such a sampling device

Номер: US20180116641A1
Принадлежит:

A sampling method using a sampling device () comprising a container () comprising a body () consisting of a soft pouch, and a lid (), in which at least one among the container () and the lid () is provided with a discharging member () suitable for, in an open state, discharging at least one part of the gases contained in the internal space () of the body () of the container (), wherein the sampling method comprises the steps consisting in:—collecting a biological material in the body () of the container (), and assembling the lid () on the neck () of the container (),—and placing an internal space () of the body () of the container () under anaerobic conditions by placing the discharging member () in the open state, by compressing the body () of the container () and by placing the discharging member () in a closed state. 12. A sampling method for sampling microorganisms contained in biological matter , the sampling method employing a sampling device () comprising:{'b': 5', '6', '7', '10', '12', '7', '6', '6', '5, 'a container () comprising a body () which comprises an internal space () configured to receive the biological matter, and a neck () which delimits an access opening () to the internal space () of the body (), the body () of the container () being constituted by a flexible bag,'}{'b': 30', '10', '5', '12', '10', '7', '6, 'a cover () configured to be removably and sealingly mounted on the neck () of the container () so as to obturate the access opening () of the neck () and close the internal space () of the body (),'}{'b': 5', '30', '25', '40', '45', '48', '7', '25', '40', '45', '48', '25', '40', '45', '48', '7', '25', '40', '45', '48', '7', '25', '40', '45', '48', '40', '7', '6', '5, 'wherein at least one of the container () and the cover () is provided with at least one transfer member (, , , ) internally comprising a passage between the internal space () and an external environment, the transfer member (, , , ) having an open state in which said transfer ...

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05-05-2016 дата публикации

Sensor system and method for sensing chlorine concentration

Номер: US20160123950A1
Принадлежит: ECOLAB USA INC

Certain embodiments include a sensor system for measuring chlorine concentration in water. The sensor system can have a manifold including one or more flow passages for receiving fluid flow. The sensor system can have a probe for measuring chlorine concentration in fluid communication with a flow passage of the one or more flow passages of the manifold. The probe can have a probe body oriented to direct incoming fluid from one or more flow passages of the manifold toward an end of the probe body. The probe can have a plurality of flutes defined on an outer surface of the probe body. The flutes can be shaped and oriented to direct fluid from the end proximal to the electrodes, back toward the one or more flow passages of the manifold.

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03-05-2018 дата публикации

MEDIA SUCTION DEVICES AND METHODS

Номер: US20180119082A1
Принадлежит: JANSSEN BIOTECH, INC.

Devices and methods are provided for removing media from a culture vessel that decreases disruption of the interface between the cellular material and media within the vessel such that aspiration and removal of cells or cell clusters along with the media is minimized. In addition, the media fluid turbulence is decreased so as to minimize the activation or disruption of cells and cell clusters. 1. An apparatus for removing media from a culture vessel containing cellular material , the apparatus comprising:a hollow tubing having a proximal portion and a distal portion, the distal portion having a curved section; andat least one opening in the curved section.2. The apparatus of claim 1 , wherein the opening is at a distal-most end of the distal portion.3. The apparatus of claim 2 , wherein the at least one opening in the curved section is disposed in at least one of an inside curvature of the curved section and an outside curvature of the curved section.4. The apparatus of claim 1 , wherein the at least one opening in the curved section is spaced apart from a distal peak of the curved section.5. A suction device claim 1 , comprising:a proximal portion defining a longitudinal axis; anda distal portion having a curved section defining an arc and a terminal section having an opening therein;wherein the arc is defined starting from the longitudinal axis of the proximal portion and is greater than 90°.6. The suction device of claim 5 , wherein the suction device comprises a second opening.7. The suction device of claim 6 , wherein the second opening is in the curved section.8. The suction device of claim 5 , wherein the terminal section extends beyond the curved section.9. The suction device of claim 8 , wherein the terminal section is parallel to the longitudinal axis.10. The suction device of claim 9 , wherein the suction device comprises a second opening in the terminal section.11. A cellular culture vessel claim 9 , comprising:a body configured to contain a cellular ...

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