Sample preparation for gas analysis using inductive heating

Improved gas analysis for non-gaseous samples is provided by placing the sample in direct contact with an inductive heating element, followed by inductively heating the heating element to provide gas for analysis. Disposable sample vials including such a heating element can be employed, or a sample tube including an inductive heating element can be configured to mate to the input gas line of a gas analysis system.

Vaporisation injector

The invention relates to a vaporization injector for a gas chromatograph, said injector comprising a structure ( 11 ) mounted in a detachable manner on the gas chromatograph body and including the sample introduction means, the vaporization chamber and pneumatic connections for feeding the carrier gas to the vaporization chamber and to the septum purge means, as well as pneumatic connections for evacuating the splitted sample and carrier gases.

Needle seal force sensor

Described are techniques for force sensing. A computing device is configured to have a desired force setting. A first vertical position of a needle is determined using the computer device. A control signal is sent from the computing device to a positioning device. In response to the control signal, the needle is positioned at the first vertical position. When in the first vertical position, surfaces of a tip of the needle are in contact with surfaces of an opening of a sealing member and positioning the needle causes application of a force at surfaces of the opening in contact with surfaces of the tip of the needle. In response to application of the force, a spring is compressed a distance that is proportional to the force. The force is measured using a force sensor.

Helium Conservation Device for a Gas Chromatograph

A device for conserving helium gas in a gas chromatograph system is characterized in that during the majority of an analytical separation, helium is used as the carrier gas while an auxiliary non-helium gas is used to pressurize the inlet and provide for septum purge and split vent flow. Prior an injection period, a coaxial helium flow is established at the column entrance wherein the coaxial helium flow is less than the column flow. Following the injection and sample transfer period, a coaxial helium flow is established wherein the flow is greater than the column flow.

Optically heated analyte desorber for gas chromatography analysis

Analytes are rapidly desorbed from a carbonaceous sorbent powder with improved quantitation and reduced analyte re-adsorption, thermal degradation, and rearrangement. The sample is distributed in a thin layer onto a desorption surface within a chamber. The layer can be a monolayer. Heating light irradiates the sample through a window, directly and rapidly heating the sample while the desorbed analytes diffuse into a vacuum or are removed by a carrier gas. Finally, the sorbent is flushed from the chamber by a transport gas. The desorption surface can be an inner surface of the window, or a surface of a porous frit that divides the chamber into two sections. The frit can be stainless steel or glass. The carrier gas can be helium, argon, or carbon dioxide. The light source can be a tungsten halogen lamp. A heater can control the chamber temperature according to a heating profile.

MEMBER COUPLING MECHANISM

A member coupling mechanism capable of coupling two members using a necessary tightening force even in a limited space by a small and simple configuration. A member coupling mechanism includes a first member including a member coupling portion having an open apical surface, a second member coupled to the member coupling portion of the first member, an elastic sealing member inserted between the first member and the second member to seal an opening of the apical surface of the member coupling portion, a coupling member that couples the first member and the second member together, and an acting portion that exerts a force on the coupling member. 1. A member coupling mechanism comprising:a first member including a member coupling portion having an open apical surface;a second member coupled to the member coupling portion of the first member;an elastic sealing member inserted between the first member and the second member to seal an opening of the apical surface of the member coupling portion;a coupling member including a first engaged portion engaged with an end portion on a side of the apical surface in the member coupling portion of the first member, a second engaged portion engaged with an end portion of the second member on a side of the first member, the second member being disposed on a side of the member coupling portion of the first member, and an elastically deformed portion which is elastically deformed and generates an elastic force for deforming the elastic sealing member by an amount necessary for airtightness by pressing the elastic sealing member using the first engaged portion and the second engaged portion in a direction in which the first engaged portion and the second engaged portion approach each other when an deformation amount becomes a predetermined amount; andan acting portion that exerts a force for elastically deforming the elastically deformed portion on the coupling member.2. The member coupling mechanism according to claim 1 , wherein both ...

Instrument for analytical sample preparation

An instrument for extraction based molecular sample preparation and related processes is disclosed. The instrument includes a thermally conductive pressure resistant heating chamber and a thermally conductive sample cup positioned in the thermally conductive pressure resistant heating chamber for heating liquids and solids together in the thermally conductive sample cup. A liquid delivery inlet fixture in the thermally conductive pressure resistant heating chamber delivers liquids (solvent) from a supply to the thermally conductive sample cup in the thermally conductive pressure resistant heating chamber, and a chiller in liquid communication with the thermally conductive sample cup in the thermally conductive pressure resistant heating chamber receives heated liquids from the thermally conductive pressure resistant heating chamber when the chamber is opened to atmospheric pressure.

Opening sealing structure, sample vaporization unit, and gas chromatograph

An opening sealing structure is provided with a housing, a step portion, a seal cap, an elastic sealing member, and a cap fixture. The housing has a cap mounting portion having a a cylindrical shape. The step portion is provided on the outer peripheral surface of the cap mounting portion and has a side surface facing the base end side of the cap mounting portion. The side surface of the step portion is inclined along the circumferential direction of the cap mounting portion from the tip end side of the cap mounting portion to the base end side and its inclination angle is smaller on the base end side of the cap mounting portion than on the tip end side. The cap fixture has a cap holding portion movably engaged with the seal cap in a circumferential direction of its outer peripheral surface and an elastic portion connected to the cap holding portion. The elastic portion is provided with a protrusion which engages the side surface of the step portion.

Systems and Methods for Conserving Carrier Gas

A device for a gas chromatograph system includes an injector, a conduit assembly, a flow restrictor, and a pressure controller. The injector is connected to a carrier gas source and an auxiliary gas source. The conduit assembly surrounds the input end of an analytical column. A carrier gas is supplied at a constant pressure through a flow restrictor to the injector. A pressure controller is configured to control the pressure of an auxiliary gas supplied to the injector from the auxiliary source. The pressure controller is configured to operate in a first mode to provide a first auxiliary gas pressure sufficient to force a flow of the auxiliary gas and a sample onto the analytical column during an inject phase and to operate in a second mode to provide a second auxiliary gas pressure below a threshold necessary to flow auxiliary gas into the analytical column during a resolving phase.

AUTOMATED THERMAL DESORPTION SYSTEMS AND METHODS

According to embodiments of the technology, an automated thermal desorption system includes a sample tube including a chamber to contain an analyte, visible indicia on the sample tube, a thermal desorption apparatus, and a sample tube monitoring system. The thermal desorption apparatus is configured to receive the sample tube and includes a heating device. The heating device is configured to heat the sample tube in the thermal desorption apparatus and thereby desorb the analyte from the sample tube. The sample tube monitoring system includes: an optical sensor configured to read the visible indicia on the sample tube and to generate an output signal corresponding thereto; and a controller configured to receive the output signal corresponding to the visible indicia from the optical sensor and to determine an orientation of the sample tube with respect to the thermal desorption apparatus based on the output signal. 1. An automated thermal desorption system including:a sample tube including a chamber to contain an analyte;visible indicia on the sample tube;a thermal desorption apparatus configured to receive the sample tube and including a heating device, wherein the heating device is configured to heat the sample tube in the thermal desorption apparatus and thereby desorb the analyte from the sample tube; and 'an optical sensor configured to read the visible indicia on the sample tube and to generate an output signal corresponding thereto; and', 'a sample tube monitoring system includinga controller configured to receive the output signal corresponding to the visible indicia from the optical sensor and to determine an orientation of the sample tube with respect to the thermal desorption apparatus based on the output signal.2. The automated thermal desorption system of wherein the visible indicia is a barcode.3. The automated thermal desorption system of wherein the barcode is substantially permanently located on the sample tube.4. The automated thermal desorption ...

Sample injector with disconnectable injection needle

A sample injector ( 500 ) for injecting a fluid into a fluidic path, wherein the sample injector ( 500 ) comprises a robot arm ( 502 ) configured for moving an injection needle ( 506 ), when being connected to the robot arm ( 502 ), between a fluid container ( 510 ) containing the fluid and a seat ( 508 ) in fluid communication with the fluidic path, the injection needle ( 506 ) configured for aspirating the fluid from the fluid container ( 510 ), when the injection needle ( 506 ) has been moved to the fluid container ( 510 ), and for injecting aspirated fluid into the fluidic path, when the injection needle ( 506 ) is accommodated in the seat ( 508 ), and the seat ( 508 ) configured for accommodating the injection needle ( 506 ) and providing fluid communication with the fluidic path, wherein the robot arm ( 502 ) is configured for selectively disconnecting the injection needle ( 506 ) from the robot arm ( 502 ) when the injection needle ( 506 ) is accommodated in the seat ( 508 ), and wherein the robot arm ( 502 ) is configured for performing a further task while the injection needle ( 506 ) is disconnected from the robot arm ( 502 ).

Gas chromatograph device with positioning system for the inlet liner and the column and method of use thereof

A gas chromatograph with a positioning system for the inlet liner and the column includes a column and the positioning system for the inlet liner and the column. The column is configured for gas chromatography. Wherein, the positioning system for the inlet liner and the column is configured to position the inlet liner and the column with respect to one another. The positioning system for the inlet liner and the column is configured to repeatably and optimally position the inlet liner and the column with respect to one another. The positioning system for the inlet liner and the column positions the inlet liner in a perpendicular orientation to the column.

Hybrid capillary/packed trap and method of use

A hybrid trap including a replaceable open-tubular capillary trap followed by a packed trap is used to collect, preconcentrate, and recover a sample, such as VOCs and SVOCs found in air. The capillary stage prevents losses and carryover of the heavy fraction and can also collect the particles in air that contain the heavier SVOCs, also preventing them from reaching the packed stage. The packed stage traps lighter organic compounds that are not as prone to carryover due to channeling. The capillary and packed traps together provide quantitative recovery of compounds boiling from as low as −50° C. to as high as 600° C. The sample can be directly desorbed onto the GC column, which avoids losses and contamination caused by other approaches that thermally desorb samples through transfer lines and rotary valves more remote to the GC oven.

Method for analyzing a cork stopper for the presence of 2,4,6-trichloroanisole and device for performing the same

A non-destructive method for analyzing a cork stopper for the presence of 2,4,6-trichloroanisole. The stopper is introduced into a hermetically closed container. The container containing the stopper is heated under conditions vaporizing any 2,4,6-trichloroanisole present in the stopper. A gaseous sample of the atmosphere surrounding the stopper in the container is collected and analyzed for the presence of 2,4,6-trichloroanisole. This method allows the selection, in a batch of cork stoppers, of the stoppers that are substantially free of 2,4,6-trichloroanisole, in a non-destructive manner.

Rapid Equilibrator for Water Isotope Analysis

Technologies for rapid equilibration for water isotope analysis are disclosed. In at least one illustrative embodiment, a vaporizer may include an injection block that defines a chamber and a septum positioned over an inlet of the chamber to seal the chamber. The chamber may be configured to be fluidly coupled to a pump to develop a vacuum within the chamber, and the septum may be configured to receive a needle that is inserted into the chamber. A thermally conductive wool may be positioned within the chamber and may be configured to receive a tip of the needle. 1. A vaporizer comprising:an injection block that defines a chamber, wherein the chamber is configured to be fluidly coupled to a pump to develop a vacuum within the chamber,a septum positioned over an inlet of the chamber to seal the chamber, the septum configured to receive a needle that is inserted into the chamber, anda thermally conductive wool positioned within the chamber and configured to receive a tip of the needle.2. The vaporizer of claim 1 , wherein the injection block is configured to be heated to heat the thermally conductive wool.3. The vaporizer of claim 2 , wherein the injection block is configured to be heated with at least one of a resistive heating element claim 2 , an inductive heating element claim 2 , or an infrared light.4. The vaporizer of claim 2 , wherein the thermally conductive wool is configured to heat the tip of the needle.5. The vaporizer of claim 1 , wherein the wool is configured to be heated with at least one of a resistive heating element claim 1 , an inductive heating element claim 1 , or an infrared light.6. The vaporizer of claim 1 , wherein the needle is configured to be heated with at least one of a resistive heating element claim 1 , an inductive heating element claim 1 , or an infrared light.7. The vaporizer of claim 1 , wherein the thermally conductive wool comprises a wire mesh.8. The vaporizer of claim 1 , wherein the thermally conductive wool comprises at least ...

Automated analysis systems

The disclosure relates to systems and methods for performing high performance liquid chromatography (HPLC) on a liquid sample. The methods include automatically, using a computer, controlling a liquid sample including a plurality of components to flow through a first flow path in a system for HPLC. Flowing through the first flow path includes flowing the liquid sample through a capture column. The capture column is capable of trapping at least some of the components of the liquid sample. The method includes automatically, using the computer, controlling a solvent to flow through a second flow path in the system for HPLC. Flowing through the second flow path includes flowing the solvent through the capture column to elute the trapped components from the capture column; flowing the solvent and eluted components through an analysis column capable of separating the eluted components; and flowing the separated components to a detector.

Quantification of asphaltene inhibitors in crude oil using thermal analysis coupled with mass spectrometry

The present invention generally relates to a novel method for the characterization and quantification of involatile macromolecules in hydrocarbon samples of crude oil. More particularly, the method utilizes pyrolysis/gas chromatography/mass spectrometry (PY/GC/MS, PY/GC/MS/MS or PY/GC/triple quad MS) to detect and quantify polymeric asphaltene inhibitors in crude oil.

ANALYSIS SYSTEM, ANALYSIS ASSISTANCE DEVICE, ANALYSIS EXECUTION METHOD AND ANALYSIS ASSISTANCE METHOD

At least one of method information representing an analysis execution method to be used for analysis of a sample and device information for specifying the configuration of an analysis device is acquired as analysis information by an analysis information acquirer. Syringe information for specifying the configuration of a syringe is acquired by a syringe information acquirer. Based on the analysis information and the syringe information, whether the syringe is suitable for analysis of the sample is judged by a judge. The result of judgement by the judge is presented by a presenter. 1. An analysis system comprising:an analysis device that includes an analyzer for analyzing a sample and a sample injector that has a syringe and supplies the sample to the analyzer;an analysis information acquirer that acquires at least one of method information representing an analysis method to be used for analysis of the sample and device information for specifying a configuration of the analysis device as analysis information;a syringe information acquirer that acquires syringe information for specifying a configuration of the syringe;a judge that judges whether the syringe is suitable for analysis of the sample based on the analysis information acquired by the analysis information acquirer and the syringe information acquired by the syringe information acquirer; anda presenter that presents a result of judgement by the judge.2. The analysis system according to claim 1 , whereinthe presenter presents the result of judgement in a case where the judge judges that the syringe is unsuitable for analysis of the sample.3. The analysis system according to claim 1 , whereinthe syringe information acquired by the syringe information acquirer includes any or all of a barrel size, a barrel material, a plunger size, a plunger material, a tip shape, a tip material and a size of a needle of the syringe.4. The analysis system according to claim 1 , whereinthe judge judges that the syringe is ...

Fluid Transfer from Digital Microfluidic Device

Methods and systems for processing fluids utilizing a digital microfluidic device and transferring droplets from the digital microfluidic device to a downstream analyzer are described herein. Methods and systems in accordance with the present teachings can allow for the withdrawal of fluid from a digital microfluidic device, and can in some aspects enable the integration of a digital microfluidic device as a direct, in-line sample processing platform from which a droplet can be transferred to a downstream analyzer. 1. A method of processing a sample comprising:disposing a sample droplet between a top plate and a bottom plate of a digital microfluidic device, andremoving at least a portion of the droplet from the digital microfluidic device via a sampling hole extending through the plate.2. The method of claim 1 , further comprising:pre-filling the sampling hole with an aqueous solution to form an extraction droplet in the sampling hole,contacting the sample droplet and the extraction droplet with one another so as to form a merged droplet at least partially disposed in the sampling hole, wherein at least a portion of the merged droplet is removed from the digital microfluidic device via the sampling hole.3. The method of claim 2 , further comprising transferring the merged droplet to an analysis device.4. The method of claim 2 , further comprising moving the sample droplet toward the sampling hole by actuating one or more actuation electrodes associated with the bottom plate.5. The method of claim 4 , wherein moving the sample droplet toward the sampling hole comprises manipulating the sample droplet to be disposed adjacent the sampling hole.6. The method of claim 4 , wherein a plurality of actuation electrodes are disposed within the bottom plate claim 4 , and wherein actuating the plurality of actuation electrodes comprises controlling the voltages applied to the different actuation electrodes so as to move the sample droplet.7. The method of claim 1 , wherein at ...

Automated Apparatus for Sample Pyrolysis

An apparatus for generating gas from a sample (battery) by pyrolysis of the sample in order to collect or analyze gas generated inside the sample due to the thermal behaviors of the sample. More specifically, provided is an apparatus wherein not only gas generated due to the thermal behaviors of a sample (battery) can be generated by heating the sample (battery itself), but also a series of processes provided to collect or analyze the generated gas can be automatically controlled.

Qualitative and Quantitative Analysis Method for High Molecular Weight Additive by Using Size-Exclusion Chromatography-Pyrolysis-Gas Chromatography/Mass Spectrometry

A method for securing qualitative and quantitative information of a high molecular weight additive in a polymer resin sample is disclosed herein. In some embodiments, the method includes separating a fraction of a polymer resin sample using size exclusion chromatography (SEC), wherein the fraction corresponding to a high molecular weight additive, pyrolyzing the fraction in a pyrolysis-gas chromatography/mass spectrometer (Py-GC/MS) to obtain a mass spectrum of the pyrolyzed fraction; identifying a structure of the high molecular weight additive by comparing m/z values for fragment peaks in the mass spectrum to m/z values for fragment peaks in a mass spectrum of a standard, and determining the amount of the high molecular weight additive in the polymer resin sample, relative to the total weight of the polymer resin sample by comparing a sum of areas of the fragment peaks to a calibration line of the standard. 1. A method of analyzing a polymer resin sample , the polymer resins sample comprising a polymer resin and a high molecular weight additive containing a piperidine or a morpholine moiety , the method comprising:separating a fraction of the polymer resin sample using size exclusion chromatography (SEC), wherein the fraction corresponding to the high molecular weight additive;pyrolyzing the fraction in a pyrolysis-gas chromatography/mass spectrometer (Py-GC/MS) to obtain a mass spectrum of the pyrolyzed fraction;identifying a structure of the high molecular weight additive by comparing m/z values for fragment peaks derived from the piperidine or the morpholine moiety in the mass spectrum to m/z values for fragment peaks derived from the piperidine or the mopholine moiety from a mass spectrum of a standard, the standard being a solution of the high molecular weight additive; anddetermining the amount of the high molecular weight additive in the polymer resin sample, relative to the total weight of the polymer resin sample by comparing a sum of areas of the ...

DEVICES, SYSTEMS AND METHODS FOR ANALYZING FLUID STREAMS

Certain embodiments described herein are directed to systems and methods that can be used to analyze species in a fluid stream. In some configurations, a sorbent tube effective to directly sample aromatics and/or polyaromatics in a fluid stream is described. 110-. (canceled)11. A sorbent tube effective to reversibly adsorb BTEX and PAHs analytes within a range of C4 to C44 in a liquefied petroleum gas stream , the sorbent tube comprising:a body comprising (i) and inlet and an outlet; and (ii) three sorbent each of which is different and separated from each other by a fluid permeable barrier, the three sorbent materials comprising glass beads and two different graphitized carbon blacks, and arranged to occupy the entire internal volume of the body with a strongest adsorption strength adjacent to the outlet and the glass beads adjacent to the inlet, wherein the glass beads comprise a surface area to adsorb BTEX and PAH analyte species with 22 carbons or more in the liquefied petroleum gas stream, and wherein the other sorbent materials adsorb the BTEX and PAH analytes within a range of C4 to C44 other than the BTEX and PAH analyte species with 22 carbons or more adsorbed by the glass beads.12. The sorbent tube of claim 11 , further comprising at least one additional sorbent material in the body claim 11 , wherein the two different graphitized carbon blacks and the at least one additional sorbent material are packed in the body from a weakest adsorption sorbent strength adjacent to the glass beads at the inlet and the strongest sorbent strength adjacent to the outlet.13. The sorbent tube of claim 12 , in which the at least one additional sorbent material comprises glass wool.14. The sorbent tube of claim 12 , in which the at least one additional sorbent material comprises glass particles.15. The sorbent tube of claim 12 , in which the at least one additional sorbent material comprises a graphitized carbon black.1618-. (canceled)19. The sorbent tube of claim 11 , ...

Pretreatment Method For Analyzing Dioxin Compounds And Analytical Method Using The Same

A pretreatment method for analyzing dioxin compounds and an analytical method using the same, in which a column packed with polymer beads that are capable of selectively adsorbing dioxin compounds is used in a purification step during pretreatment, thereby remarkably reducing a time required for pretreatment and improving a recovery rate of an internal standard for purification, are provided. 1. A pretreatment method for analyzing dioxin compounds , the method comprising the steps of:1) obtaining a liquid extract including dioxin compounds from a sample;2) adsorbing the dioxin compounds onto polymer beads by passing the liquid extract through a column packed with the polymer beads;3) removing substances which are not adsorbed onto the polymer beads by passing a first solvent through the column packed with the dioxin compound-adsorbed polymer beads; and4) obtaining an eluate including dioxin compounds which are eluted in a second solvent by passing the second solvent through the column packed with polymer beads from which the unadsorbed substances have been removed, wherein the polymer beads are porous particles including one or more hydrophobic repeating units derived from a vinyl aromatic monomer having a non-polar functional group and one or more hydrophilic repeating units derived from a vinyl aromatic monomer having a polar functional group.2. The pretreatment method for analyzing dioxin compounds of claim 1 ,wherein the dioxin compounds are polychlorinated dibenzo-p-dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), or a combination thereof.3. The pretreatment method for analyzing dioxin compounds of claim 1 ,wherein extraction of the liquid extract is performed by liquid-liquid extraction, solid phase extraction, Soxhlet extraction, or a combination thereof.4. The pretreatment method for analyzing dioxin compounds of claim 1 ,wherein the polymer beads include the hydrophobic repeating unit and the hydrophilic repeating unit at a molar ratio of 99:1 to 40: ...

Proteoform Specific Process Validation

A system and method is provided for validating the manufacturing process for the production of complex biological compositions, and particularly for providing process validation information for evaluation by a federal regulatory agency. The system and method continuously and chronologically assess the concentration of proteoforms within the biological composition as it is being produced in a fermentor. Samples from the fermentor are analyzed in a pre-selected array of analysis columns, with data generated by the columns being accumulated and evaluated, and particularly compared with data from previous stages in the production process. A continuous process validation system includes top-down and bottom-up analysis sectors, each including a plurality of different analysis columns that can be selected by the controller for a particular biological composition and a particular production process.

Methods For Analyzing Hydrocarbons And Hydrocarbon Blends For Chemical Compositions

The present invention is generally related to the analysis of chemical compositions of hydrocarbons and hydrocarbon blends. This method applies specifically to the problem of analyzing extremely complex hydrocarbon-containing mixtures when the number and diversity of molecules makes it impossible to realistically identify and quantify them individually in a reasonable timeframe and cost. The advantage to this method over prior art is the ability to separate and identify chemical constituents and solvent fractions based on their solvent-solubility characteristics, their high performance liquid chromatographic (HPLC) adsorption and desorption behaviors, and their interactions with stationary phases; and subsequently identify and quantify them at least partially using various combinations of non-destructive HPLC, destructive HPLC, and stand-alone detectors presently not routinely used for HPLC but reconfigured to obtain spectra on the fly. This analytical method is especially useful for, but not limited to, asphalt binders and asphalt binder blends, modified asphalts, asphalt modifiers, asphalt additives, polymer-modified asphalts, asphalts containing rejuvenators and softening agents, asphalts containing recycled products, aged asphalts, and air-blown asphalts, which may contain wide varieties of different types of additives and chemistries, and forensic applications, and environmental pollutant identification.

HEATING APPARATUS FOR A GAS CHROMATOGRAPH, AND HEATING METHOD FOR A GAS CHROMATOGRAPH

To provide a heating apparatus for a gas chromatograph, and a heating method for a gas chromatograph, wherein vapor phase components can be analyzed at an arbitrary temperature and can be instantaneously heated and pyrolized at a set temperature, thereby enabling analysis to be carried out with good reproducibility. The heating apparatus for a gas chromatograph is structured in that the ceramic heater is disposed around the periphery of the sample tube to heat the sample housed in the sample tube , the temperature of the sample is incrementally elevated, and the high-frequency coil , disposed around the periphery of the ceramic heater , heats the pyrofoil wrapping the sample to the Curie point, and the sample is instantaneously heated and pyrolized. 1. A heating apparatus for a gas chromatograph having a sample housed in a sample tube is heated for producing a vapor phase component , the vapor phase component being transported by a carrier gas from the sample tube to a detector , comprising:a temperature-elevating heating section for heating the sample; andan instantaneous heating section for heating and pyrolyzing the sample by heating a ferromagnetic material around the sample to a Curie point.2. The heating apparatus for a gas chromatograph according to claim 1 , wherein the temperature-elevating heating section is spaced away around a periphery of the sample tube claim 1 , and the instantaneous heating section is spaced away around a periphery of the temperature-elevating heating section.3. The heating apparatus for a gas chromatograph according to claim 1 , further comprising an adsorption tube for collecting a vapor phase component split out from the sample tube.4. The heating apparatus for a gas chromatograph according to claim 1 , further comprising:a valve capable of switching between a first state in which a first port and an eighth port are communicated, a second port and a third port are communicated, a fourth port and a fifth port are communicated, and ...

SAMPLE PRECONCENTRATION SYSTEM AND METHOD FOR USE WITH GAS CHROMATOGRAPHY

The disclosed system and method concentrates and enriches a chemical sample while removing water and/or CO2 prior to analysis, improving detection limits and repeatability of quantitative chemical analysis without the need for cryogenic or sub-ambient cooling. The system can include a valve system, a dewpoint control zone, and a multi-capillary column trapping system (MCCTS). During a first time period, the valve system can couple the dewpoint control zone to the MCCTS. During a second time period, the valve system can couple the MCCTS to the chemical separation column such the dewpoint control zone is bypassed. Excess water included in the sample can condense in the dewpoint control zone as the sample transfers to the dewpoint control zone and MCCTS. When the sample is transferred from the MCCTS to the chemical separation column, the condensed water in the dewpoint control zone is not transferred to a chemical separation column. 1. A chemical analysis system , comprising:a valve system;a dewpoint control zone, the dewpoint control zone comprising a tube having a first end and a second end, wherein the first end of the dewpoint control zone tube is fluidly coupled to a sample source and the second end of the dewpoint control zone is coupled to the valve system;a multi-capillary column trapping system (MCCTS), the MCCTS comprising a first end and a second end, the first end of the MCCTS fluidly coupled to the valve system;a chemical separation column having a first end and a second end, the first end of the chemical separation column fluidly coupled to the valve system; and during a first time period, couple the second end of the dewpoint control zone tube to the first end of the MCCTS, and', 'during a second time period after the first time period, couple the first end of the MCCTS to the chemical separation column., 'a detector coupled to the second end of the chemical separation column, wherein the valve system is configured to2. The chemical analysis system of ...

Detection of Substances of Interest Using Gas-Solid Phase Chemistry

The present disclosure is directed to methods and systems for detecting a chemical substance. The methods and systems include using gas-solid phase chemistry to chemically and/or physically modify a substance of interest so that the substance can be vaporized and detected through an analysis of the substance. 1. A substance detection system , the system comprising:a sampling trap including a substantially non-volatile substance of interest;a housing including a clustering agent, the housing configured to vaporize the clustering agent;a thermal desorber configured to receive the sampling trap, wherein the desorber is configured to vaporize the substance of interest;a transfer line, wherein the transfer line connects the housing to the desorber and transfers the vaporized clustering agent from the housing to the desorber, wherein the vaporized clustering agent increases the volatility of the substance of interest;an analysis device coupled in flow communication with the desorber, the analysis device configured to receive the vaporized substance of interest from the desorber and perform an analysis of the substance of interest.2. The system of claim 1 , wherein the clustering agent includes at least one of an organic acid claim 1 , a crown ether claim 1 , an amine claim 1 , an ester claim 1 , an amide and combinations thereof.3. The system of claim 1 , wherein the substance of interest includes at least one of an explosive claim 1 , an energetic material claim 1 , a taggant claim 1 , a narcotic claim 1 , a toxin claim 1 , a chemical warfare agent claim 1 , a biological warfare agent claim 1 , a pollutant claim 1 , a pesticide claim 1 , a toxic industrial chemical claim 1 , a toxic industrial material claim 1 , a homemade explosive claim 1 , a pharmaceutical trace contaminant and combinations thereof.4. The system of claim 3 , wherein the substance of interest includes at least one of nitrates claim 3 , chlorates claim 3 , perchlorates claim 3 , nitrites claim 3 , ...

REFERENCE SAMPLE FOR ANALYSIS

A reference sample for analysis that is optimal for calibration of a pyrolysis gas chromatograph-mass spectrometer and with which precise calibration is always possible by preventing a reference substance from evaporating is provided. A reference sample sheet is provided by distributing a target component or target components with a uniform normality in a base made of a high polymer material, and the reference sample sheet is rolled up so that the target component or target components can be prevented from evaporating from the reference sample sheet even in the case where a component has volatility. A reference sample for calibration of a pyrolysis gas chromatograph-mass spectrometer can be easily, quickly, and efficiently collected by punching out the reference sample sheet using a micro-puncher 1. A calibration method for a pyrolysis gas chromatograph-mass spectrometer , where a pyrolyzer is arranged in a front stage of an injection port for a sample gas to be subjected to a gas chromatograph so that a gas generated by heating a sample in the pyrolyzer is introduced through the injection port of the gas chromatograph so as to pass through a separation column and then be led to a mass spectrometer for analysis , the method comprising:forming a reference sample sheet where at least one target component is distributed in a base made of a high polymer in such a manner that the normality is uniform;taking a necessary amount of the reference sample sheet for calibration at the time of the calibration, wherein the necessary amount of the reference sample sheet is taken by using a puncher to punch out the reference sample sheet; andheating the necessary amount of the reference sample sheet in the pyrolyzer for direct analysis without carrying out solvent extraction.2. The calibration method for the pyrolysis gas chromatograph-mass spectrometer according to claim 1 , wherein the reference sample sheet is a sheet roll.3. The calibration method for the pyrolysis gas ...

Method and apparatus for inspecting a gas sample

An apparatus for detecting a presence of at least one analyte in a gas sample. The apparatus comprises a pump for drawing a gas sample from an ambient air, a passage having first and second ends, a chamber connected to the first end and containing a concentrating element for collecting at least one analyte from the gas sample, a chromatographic separator connected to a second end of the passage, and a gas source for streaming a carrier gas via the chamber to transfer the at least one analyte toward at least one chemical detector, via the chromatographic separator, in a first direction. The pump draws the gas sample via the chamber in a second direction and the first and second directions are substantially opposing to one another.

Sampling pumps and closed loop control of sampling pumps to load traps

Certain configurations of devices and systems which are configured to draw a selected volume of an air sample into a trap are described. In some examples, the devices and systems comprise a pump and a mass flow sensor to draw a selected volume of the air sample through a trap even where variable restriction occurs.

Method for Simultaneous Determination of Nitrogen And Oxygen Isotope Compositions of Natural Nitrate and Nitrite

The disclosure describes a method for simultaneous determination of nitrogen and oxygen isotope compositions of natural nitrate and nitrite, which quantitatively converts natural nitrate and nitrite into an organic ester and a nitro-compounds respectively, and then nitrate and nitrite δ18O and δ15N are simultaneously determined by adopting a gas chromatography/pyrolysis/gas chromatography/isotope ratio mass spectrometry coupling technology (GC/Py/GC/IRMS). According to the method for simultaneously determining the nitrogen and oxygen isotope compositions of the natural nitrate salt and nitrite salt, the small amount of sample does not result in the loss, acquisition, exchange and fractionation of nitrogen and oxygen.

Staged Preconcentration and Parallel Column Gas Chromatography

We disclose a device that both extracts and preconcentrates volatile analytes in preparation for separation by gas chromatography. The device includes a conduit that may include two, and sometimes three, separate sections that are connected end-to-end, but which may be separated prior to inserting into a gas chromatograph port. The inner surface of each section is coated with one or more sorbents, each with a different affinity for volatile analytes. The sorbents may be positioned along the sections of the column in order of relative affinity for volatile analytes. The sections may be heated independently of each other to release the volatile analytes from the sorbents more quickly. This device reduces the time and the temperature required to achieve separation by gas chromatography. The device may be used to perform gas chromatography in ubiquitous environments such as the home or a mobile situation.

Adapter housing and connecting device for chromatography

An adapter housing is described that can be used for high performance liquid chromatography, which can be releasably connected to a socket unit. The adapter housing includes a bore which passes through the adapter housing and a pre-column which can be arranged in the bore to protect the separation column from contaminants and/or to concentrate the fluid to be analyzed. A sealing element seals the adapter housing in relation to the socket unit at the end-face wall of a pilot bore.

CHAMBERED SEPTUM

A septum contains at least one internal chamber along the central axis of the septum. The chamber provides relief space into which the sealing sections of the septum can deform as a needle passes through the septum. Incorporation of the chamber reduces surface area contact and friction between the septum and needle, which results in reduced septum tearing and reduced production of particulate matter from abrasion. 1) A septum comprising:a body formed of resilient, elastomeric material, the body having a top surface, a bottom surface, and at least one side extending between the top surface and the bottom surface, the body including a central axis; andat least one internal chamber within the body, the central axis extending through the chamber.2) The septum of claim 1 , further comprising an upper seal between the at least one chamber and the top surface claim 1 , and a bottom seal between the at least one chamber and the bottom surface.3) The septum of claim 2 , wherein the upper seal has a thickness between about 0.1 mm and about 2 mm claim 2 , and wherein the lower seal has a thickness between about 0.1 mm and about 2 mm.4) The septum of claim 1 , wherein the chamber has a diameter between about 0.06 mm and 13 mm.5) The septum of claim 1 , wherein the body includes a first portion and a second portion claim 1 , the second portion including a recess sized and shaped to receive at least a portion of the first portion.6) The septum of claim 5 , wherein the first portion is cylindrically-shaped and wherein the recess is sized and shaped to receive at least a portion of the cylindrically-shaped first portion.7) The septum of claim 6 , wherein the first portion and the recess engage via a tongue-and-groove fit.8) The septum of claim 5 , wherein the chamber is formed between the first portion and the second portion.9) The septum of claim 5 , wherein the first portion is formed of a first elastomeric material claim 5 , wherein the second portion is formed of a second ...

MULTIPLE SAMPLE CHROMATOGRAPHY USING A STOCHASTIC INJECTION TECHNIQUE

The invention relates to a method for simultaneously analyzing at least two samples using a chromatography device comprising a chromatography column having an inlet and an outlet, and at least one detector placed at the outlet of the chromatography column, the method comprising steps of: injecting fractions of each independent sample at the inlet of the chromatography column, the fractions of each independent sample being injected according to a specific injection timing sequence derived from a pseudo-random binary sequence associated with said independent sample; recording a signal generated by said detector for a period of time at least equal to a duration of the longest of the specific injection timing sequences; cross-correlating the recorded signal and a derived correlation function, said derived correlation function being derived from the pseudo-random binary sequence associated with one of the independent samples, so as to obtain an individual correlogram signal specific to said independent sample; and analyzing data of interest of the individual correlogram signal so as to obtain an output signal indicative of a composition of the sample. 1. A method for simultaneously analyzing at least two samples using a chromatography device comprising a chromatography column having an inlet and an outlet , and at least one detector placed at the outlet of the chromatography column , the method comprising steps of:injecting fractions of each independent sample at the inlet of the chromatography column, the fractions of each independent sample being injected according to a specific injection timing sequence derived from a pseudo-random binary sequence associated with said independent sample;recording a signal generated by said detector for a period of time at least equal to a duration of the longest of the specific injection timing sequences;cross-correlating the recorded signal and a derived correlation function, said derived correlation function being derived from the ...

METHOD TO DETERMINE TRANSFORMATION OF KEROGEN TO OIL/GAS AT DIFFERENT MATURITIES USING STEP-WISE PYROLYSIS-GAS CHROMATOGRAPHY

A method for evaluating a degree of transformation ratio of kerogen to oil and/or gas and/or gas to oil generation index using a pyrolysis gas chromatography is disclosed. The method comprises providing a rock sample in powdered form; determining, by a source rock analysis instrument, total organic carbon in said rock sample, remaining hydrocarbon generation potential in rock sample, and a maturity of rock sample; feeding said sample in a pyrolyzer if said sample satisfies a pre-defined condition; analyzing, said sample in said pyrolyzer, by heating said sample at a pre-specified pyrolysis temperature in pre-specified pyrolysis steps and for pre-specified pyrolysis time; determining, by a gas chromatograph, a peak area of hydrocarbons present in said sample analyzed; evaluating, in a said degree of transformation ratio of said sample to oil and/or gas and/or said gas to oil generation index. 1. A method for evaluating a degree of transformation ratio of kerogen to oil and/or gas and gas to oil generation index using a pyrolysis gas chromatography , said method comprising:providing a rock sample in powdered form;determining, by a source rock analysis instrument, total organic carbon (TOC) in said rock sample, remaining hydrocarbon generation potential (S2) in rock sample, and a maturity (Tmax) of rock sample;feeding said sample in a tube of a pyrolyzer if said sample satisfies a pre-defined condition;analyzing, said sample in said pyrolyzer, by heating said sample at a pre-specified pyrolysis temperature in pre-specified pyrolysis steps and for pre-specified pyrolysis time;determining, by a gas chromatograph, a peak area of hydrocarbons present in said sample analyzed;evaluating, by said gas chromatograph, said degree of transformation ratio of said sample to oil and/or gas and/or said gas to oil generation index.2. The method as claimed in claim 1 , wherein evaluating said transformation of said sample to said oil and/or gas and/or said gas to oil generation index ...

Hydrocarbon Analysis Methods

A method for determining asphaltene stability in a hydrocarbon-containing material having solvated asphaltenes therein is disclosed. In at least one embodiment, it involves the steps of: (a) precipitating an amount of the asphaltenes from a liquid sample of the hydrocarbon-containing material with an alkane mobile phase solvent in a column; (b) dissolving a first amount and a second amount of the precipitated asphaltenes by changing the alkane mobile phase solvent to a final mobile phase solvent having a solubility parameter that is higher than the alkane mobile phase solvent; (c) monitoring the concentration of eluted fractions from the column; (d) creating a solubility profile of the dissolved asphaltenes in the hydrocarbon-containing material; and (e) determining one or more asphaltene stability parameters of the hydrocarbon-containing material. 1. A method for determining an effectiveness of one or more asphaltene dispersant additives for inhibiting or preventing asphaltene precipitation in a hydrocarbon-containing material subjected to an elevated temperature and pressure conditions , the method comprising the steps of:(a) subjecting a first column having an inert packing material therein to a first set of the elevated temperature and pressure conditions comprising a temperature ranging from 140 degree C. to 450 degree C. and a pressure ranging from 1 to 200 standard atmosphere (atm);(b) precipitating an amount of asphaltenes from a first hydrocarbon-containing material sample having solvated asphaltenes therein with one or more first asphaltene-precipitating mobile phase solvents and capturing precipitated asphaltenes in the inert packing material in the first column;{'sup': '0.5', '(c) dissolving an amount of the precipitated asphaltenes at a predetermined temperature with one or more first solvents having a solubility parameter of at least 21 MPabut no greater than 30 MPa.sup.0.5 to elute a first fraction having dissolved asphaltenes therein;'}(d) ...

DEVICE AND METHOD FOR INTERFACING TWO SEPARATION TECHNIQUES

The present invention relates to an evaporative membrane concentration device adapted to interface two liquid flow processes, such as two low or high resolution separation techniques or a low or high resolution separation technique and a liquid flow detection technique. For example, the two liquid flow processes may be a liquid chromatography technique and a liquid flow detection technique or a multi-dimensional separation technique, for example, two dimensional liquid chromatography (LC×LC) or solvent extraction, such as liquid-liquid extraction or solid phase extraction, with a liquid chromatography technique (LLE or SPE-LC). Methods of using the device and separation and/or chromatographic methods using the device are also described. 1. An evaporative membrane modulation device comprising:i) an evaporative membrane concentration module comprising a heating element;ii) a means of measuring output flow rate of a liquid sample from the module; andiii) a controller operably connected to the means of measuring flow rate of the liquid sample and operably connected to the heating element;wherein the controller adjusts the intensity of the heating element such that the output flow rate from the module is a desired output flow rate and whereinthe heating element is situated to heat the flow of liquid sample within the evaporative membrane concentration module.2. (canceled)3. The evaporative membrane device according to wherein the heating element is selected from one or more light emitting diodes claim 1 , a thermoelectric heating/cooling element claim 1 , a resistive heating element or a microwave heating element.4. (canceled)5. The evaporative membrane device according to further comprising a liquid flow channel connected to an inlet and an outlet.6. The evaporative membrane device according to wherein the liquid flow channel is etched in a polymeric material.7. The evaporative membrane device according to where the polymeric material is semi-transparent or transparent. ...

Method for preparing a sample for chromatographic separation processes and system for carrying out a sample preparation

A method for preparing a sample for chromatographic separation processes, in which a sample vessel is partially filled with a substance to be examined and is closed, is described. The substance to be examined is subjected to a thermo-chemical reaction in which at least one sample component is converted into another substance, and in which by use of a removing device samples are removed from the sample vessel for analytical examination. Also, the sample vessel forms a cavity, into which the substance to be examined is introduced as a core and a heating section for indirect heat transfer is applied along the filling of substance to be examined.

Graphene-Based Inorganic-Organic Hybrid Materials and Separation of Racemic Mixtures

A variety of inorganic-organic hybrid materials and various methods for preparing and using the same are described. The hybrid materials are graphene or graphitic materials populated with organic molecules and may have a variety of surface defects, pits or three-dimensional architecture, thereby increasing the surface area of the material. The hybrid materials may take the form of three dimensional graphene nanosheets (3D GNS). If the organic molecules are enantiospecific molecules, the hybrid materials can be used for chiral separation of racemic mixtures. 1. A method for chiral separation of racemic mixtures comprising:providing a column containing an enantioselective two- or three-dimensional graphene or graphitic material;flowing a racemic mixture through the column such that first and second enantiomers in the racemic mixture encounter the enantioselective two- or three-dimensional graphene or graphite and are separated thereby.2. The method of wherein the two- or three-dimensional graphene or graphitic material is populated with enantioselective organic molecules.3. The method of wherein the two- or three-dimensional material is a two-or three-dimensional graphene nanosheet.4. The method of comprising a three dimensional graphene nanosheet wherein the three dimensional graphene nanosheet is a non-contiguous three dimensional graphene material comprising graphene walls and voids.5. The method of wherein the non-contiguous three dimensional graphene material comprising graphene walls and voids is disordered.6. The method of claim wherein the racemic mixture is ibuprofen and the enantioselective molecule is (S)-(+)-2-pyrrolidinemethanol.7. An apparatus for chiral separation of racemic mixtures claim 4 , the apparatus comprising a column containing enantioselective two- or three-dimensional graphene or graphitic material.8. The apparatus of wherein the two- or three-dimensional graphene or graphitic material is populated with enantioselective organic molecules.9. ...

PREPROCESSING APPARATUS FOR GAS ANALYSIS

Provided herein is a preprocessing apparatus for gas analysis that enables preprocessing for gas analysis to be performed without requiring a cryogen. A preprocessing apparatus for gas analysis mainly includes a gas flow path , a cooling portion , and a plurality of valves V to V that serve as gas flow path connection changing means for changing the gas flow path. The cooling portion is operable to cool the collecting portion , and is constituted from a heat conductor , a cooling device , and a sealed structure . The cooling device can cooled a contact cooling section to an extremely low temperature by utilizing electrical energy. The cooling device is used to bring the collecting portion to a first temperature at which the target gas to be analyzed is solidified, and to thereafter bring the collecting portion to a second temperature at which only the target gas to be analyzed is gasified. By performing such processes, the target gas to be analyzed can be extracted by removing gases of impurities from a mixed gas. 1. A preprocessing apparatus for gas analysis comprising:a gas flow path including a collecting portion that is cooled to a plurality of temperature levels in order to separate a gas having the lowest solidification temperature, as a target gas to be analyzed, from a mixed gas containing a plurality of kinds of gases and to collect other kinds of gases other than the target gas, as gases of impurities;a cooling device operable to cool the collecting portion of the gas flow path to the plurality of temperature levels;a gas flow path connection changing means for connecting the gas flow path to a vacuum pump when evacuating the gas flow path, connecting the gas flow path to a gas generating source when introducing the mixed gas into the gas flow path after the gas flow path has been evacuated, and connecting the gas flow path to a gas analysis device in order to supply the target gas to be analyzed, which has been separated by the collecting portion, to the ...

Inverted Wick Type Temperature Control System

A sample vessel assembly to carry out a sorption analysis in a container provided with a cooling liquid. The sample vessel assembly includes a sample vessel configured to be suspended within the container. The sample vessel has a sample holding region at a sample end of the vessel to hold a sample to be analyzed. A wick is disposed on the sample vessel and surrounds the sample holding region. The wick extends from the sample holding region to project toward a bottom of the container and draw the cooling liquid over the sample holding region when the sample vessel is disposed in an analysis position in the container. 1. A sample vessel assembly for carrying out a sorption analysis in a container provided with a cooling liquid , the sample vessel assembly comprising:a sample vessel configured to be suspended within the container, the sample vessel having a sample holding region at a sample end of said vessel for holding a sample to be analyzed;a wick disposed on said sample vessel and surrounding said sample holding region, said wick extending from said sample holding region for projecting toward a bottom of the container and drawing the cooling liquid over said sample holding region when said sample vessel is disposed in an analysis position in the container.2. The sample vessel assembly according to claim 1 , wherein said wick includes a wick base and a wick lid that engages said wick base claim 1 , said wick base and said wick lid define a cavity there between claim 1 , said cavity is dimensioned for receiving the sample holding region therein.3. The sample vessel assembly according to claim 2 , wherein said sample vessel has a stem for insertion of a sample into said sample vessel and said wick lid has an aperture formed therein to receive said stem and allow said lid to be slid along said stem to said wick base.4. The sample vessel assembly according to claim 2 , wherein said sample vessel has a stem with a straight wall and said sample holding region has a ...

THERMAL CONDUCTIVITY DETECTOR AND GAS CHROMATOGRAPH INCLUDING SAME

A thermal conductivity detector includes a first pipe path that houses a filament, a second pipe path and a third pipe path that connects the first pipe path to the second pipe path. In the third pipe path, first, second and third gas lead-in portions are arranged in this order from the first pipe path toward the second pipe path. A carrier gas is led to the first and third gas lead-in portions alternately, and a sample gas is led to the second gas lead-in portion. The distance between the second and third gas lead-in portions is equal to or smaller than 1.3 times of a maximum dimension of an opening formed at the second gas lead-in portion. At least part of the third pipe path between the second gas lead-in portion and the third gas lead-in portion has a cross sectional area that is equal to or smaller than an area of the opening formed at the second gas lead-in portion. 1. A thermal conductivity detector for a gas chromatograph , comprising:a heat generator that is driven to maintain a certain temperature and in which a resistive value changes in accordance with thermal conductivity of a gas flowing around the heat generator;a first flow path that houses the heat generator; anda second flow path; anda third flow path that connects the first flow path to the second flow path, whereinfirst and third openings to which a carrier gas is led alternately and a second opening to which a sample gas is led are formed at the third flow path,the first opening, the second opening and the third opening are provided to be arranged in this order from the first flow path toward the second flow path,a distance between the second and third openings in the third flow path is equal to or smaller than 1.3 times of a maximum dimension of the second opening, andat least part of a portion between the second opening and the third opening of the third flow path has a cross sectional area equal to or smaller than an area of the second opening.2. The thermal conductivity detector according to ...

DETECTION OF SUBSTANCES OF INTEREST USING GAS-SOLID PHASE CHEMISTRY

The present disclosure is directed to methods and systems for detecting a chemical substance. The methods and systems include using gas-solid phase chemistry to chemically and/or physically modify a substance of interest so that the substance can be vaporized and detected through an analysis of the substance. 1. A method for detecting a substance of interest , the method comprising:collecting a sample of a substantially non-volatile substance of interest on a sampling trap;inserting the trap into a thermal desorber;introducing a vaporized clustering agent into the desorber, wherein the clustering agent increases the volatility of the substance of interest;vaporizing the substance of interest;transferring the vaporized substance of interest into a detector;performing an analysis of the substance of interest; and,detecting the substance of interest.2. The method of claim 1 , wherein the clustering agent includes at least one of an organic acid claim 1 , a crown ether claim 1 , an amine claim 1 , an ester claim 1 , an amide and combinations thereof.3. The method of claim 1 , wherein the substance of interest includes at least one of an explosive claim 1 , an energetic material claim 1 , a taggant claim 1 , a narcotic claim 1 , a toxin claim 1 , a chemical warfare agent claim 1 , a biological warfare agent claim 1 , a pollutant claim 1 , a pesticide claim 1 , a toxic industrial chemical claim 1 , a toxic industrial material claim 1 , a homemade explosive claim 1 , a pharmaceutical trace contaminant and combinations thereof.4. The method of claim 3 , wherein the substance of interest includes at least one of nitrates claim 3 , chlorates claim 3 , perchlorates claim 3 , nitrites claim 3 , chlorites claim 3 , permanganates claim 3 , chromates claim 3 , dichromates claim 3 , bromates claim 3 , iodates claim 3 , and combinations thereof.5. The method of claim 1 , wherein the vaporized clustering agent is introduced into the desorber at a flow rate of from about 5 cc/min to ...

Multi-Capillary Column Pre-Concentration System for Enhanced Sensitivity in Gas Chromatography (GC) and Gas Chromatography-Mass Spectrometry (GCMS)

A multi-capillary column pre-concentration trap for use in various chromatography techniques (e.g., gas chromatography (GC) or gas chromatography-mass spectrometry (GCMS)) is disclosed. In some examples, the trap can include a plurality of capillary columns connected in series in order of increasing strength (i.e., increasing chemical affinity for one or more sample compounds). A sample can enter the trap, flowing from a sample vial to a relatively weak column to the relatively strongest column of the trap by way of any additional columns included in the trap, for example. In some examples, the trap can be heated and backflushed so that the sample exits the trap through the head of the relatively weak column. Next, the sample can be injected into a chemical analysis device for performing the chromatography technique (e.g., GC or GCMS) or it can be injected into a secondary multi-capillary column trap for further concentration. 1. A first trap for pre-concentrating a sample before chemical analysis , the first trap comprising:a first primary capillary column having a first strength;a second primary capillary column having a second strength, greater than the first strength, the second primary capillary column coupled to the first primary capillary column in series, and during an adsorption process, allow the sample to flow through the first primary capillary column and the second primary capillary column in a first direction, the first direction being from the first primary capillary column to the second primary capillary column, and', 'during a desorption process, allow a desorption gas to flow through the first primary capillary column and the second primary capillary column in a second direction, the second direction being from the second primary capillary column to the first primary capillary column., 'one or more valves configured to2. The first trap of claim 1 , further comprising a first adsorbent material within the first primary capillary column and a second ...

Gaseous Mercury Detection Systems, Calibration Systems, and Related Methods

Embodiments disclosed herein are directed to gaseous mercury detection systems, calibration systems, and related methods. The gaseous mercury detection systems are configured to detect gas-phase mercury-compounds present in ambient air. For example, the gaseous mercury detection systems collect gas-phase mercury-compounds from ambient air and release the gas-phase mercury-compounds at concentrations capable of being measured by a gas-chromatography mass spectrometer without heating the gas-phase mercury-compounds above a decomposition temperature of at least one gaseous mercury compound that may present in the mercury-containing gas. The calibration systems are configured to determine an accuracy of or calibrate a gaseous mercury detection system. The disclosed calibration systems may be integrated with or distinct from the gaseous mercury detection systems disclosed herein. 1. A method of collecting and releasing Gaseous Mercury Oxide , Gaseous Mercury Sulfate , Gaseous Mercury Nitrite , Gaseous Mercury Nitrate , Gaseous Mercury Iodide , or Gaseous Mercury Fluoride in ambient air , the method comprising:cooling a collection surface to a collection temperature within five degrees Celsius above of the ambient-air dew point temperature;drawing over the collection surface the ambient air at a collection flow rate;collecting on the collection surface the at least one of Gaseous Mercury Oxide, Gaseous Mercury Sulfate, Gaseous Mercury Nitrite, Gaseous Mercury Nitrate, Gaseous Mercury Iodide, or Gaseous Mercury Fluoride present in the ambient air, the Gaseous Mercury Oxide, Gaseous Mercury Sulfate, Gaseous Mercury Nitrite, Gaseous Mercury Nitrate, Gaseous Mercury Iodide, or Gaseous Mercury Fluoride becoming Mercury Oxide, Mercury Sulfate, Mercury Nitrite, Mercury Nitrate, Mercury Iodide, or Mercury Fluoride on the collection surface;heating the collection surface to a temperature sufficient to release the at least one of Mercury Oxide, Mercury Sulfate, Mercury Nitrite, ...

Breath analyzer

A cooling unit (cryo-focus unit) cools breath introduced into a carrier gas from a sample introduction unit, to trap volatile components in the breath into a column. A heater heats the volatile components trapped in the column to desorb the volatile components. Amass spectrometry (MS) section detects the volatile components desorbed by the heater and separated in a process of passing through the column. The breath introduced into the carrier gas from the sample introduction unit is cooled by the cooling unit, whereby more volatile components in the breath are trapped, and those volatile components can be desorbed, and can be detected by the MS section.

METHOD OF DETECTING AN ANALYTE USING CHROMATOGRAPHIC ENRICHMENT

A device is provided. The device comprises a casing comprising an interior, a first opening, and a second opening; and a porous carrier comprising a sample-receiving zone and a target analyte-binding zone. The porous carrier defines a first fluid pathway that extends from the sample-receiving zone to the target analyte-binding zone. At least portion of the porous carrier is disposed in the interior of the casing. A second fluid pathway comprising a central axis extends through the casing from the first opening and the second opening, the second fluid pathway intersecting the porous carrier at the target analyte-binding zone. The central axis is oriented orthogonally with respect to the porous carrier. Methods of using the device to detect a target analyte are also provided. 1. A method of detecting a target microorganism , comprising: a casing comprising a first and second opening; and', wherein the porous carrier comprises a sample-receiving zone at a first predefined location and an target analyte-binding zone at a second predefined location, the porous carrier defining a first fluid pathway extending from the sample-receiving zone through the target analyte-binding zone;', 'wherein at least portion of the porous carrier is disposed in the casing;, 'the porous carrier;'}, 'wherein a second fluid pathway extends through the casing from the first opening to the second opening, the second fluid pathway intersecting the porous carrier at the target analyte-binding zone;, 'contacting a liquid sample with a porous carrier of a sample preparation device, the device comprisingallowing at least a portion of the liquid sample to move longitudinally through the porous carrier from the sample-receiving zone toward the target analyte-binding zone;after the at least a portion of the liquid has moved to the target analyte-binding zone, urging a detachment member through the second fluid pathway from the first opening to the second opening and thereby expelling a portion of the ...

Fast Gas Chromatographic System used for the Rapid Analysis of Components Spanning a Wide Molecular Weight Range

A chromatographic system for rapid analysis of fluid components having a wide molecular range in a single sample is disclosed. A single isothermal oven having a switching valve controls the flow between a single column module and a dual column module. The single column module contains a shielded column with an input receiving components from a sample input and output to a detector via the valve. The dual column module contains two shielded columns wrapped adjacent one another on a single ring with separate inputs and outputs and in communication with one another and detectors through the switching valve. One or both columns in the dual column module can be heated and monitored with one or more sensor wires. 1) A chromatographic system for rapid analysis of fluid components having a wide molecular range in a single sample having: i. a sample inlet;', 'ii. a switching valve, said switching valve having multiple ports, an active state, and an inactive state; and', 'iii. fluid communication members;', 'iv. a carrier gas inlet;, 'a. an isothermal oven, said isothermal oven comprising i. a single column, said single column having sheathing along a majority of its length and an unsheathed section at each end;', 'ii. single inlet port, said single inlet port in fluid communication with said single column and said sample inlet;', 'iii. single outlet port said single outlet port in fluid communication with said single column and said switching valve;, 'b. a single column module, said single column module comprisingc. a first detector module, said first detector module in fluid communication with said switching valve;{'b': '140', 'd. a second detector module ();'}{'b': 180', '160, 'claim-text': [{'b': '162', 'i. a second column ();'}, {'b': '204', 'ii. a second inlet port (), said second inlet port in fluid communication with said second column and said switching valve;'}, {'b': '202', 'iii. a second outlet port (), said second outlet port in fluid communication with said ...

AUTOSAMPLER SEAL PACK FOR REDUCING A CARRYOVER PERCENTAGE

A seal pack of a sample manager of a liquid chromatography system having a plurality of wash flow pathways fluidically connected to a central pathway that accommodates a sample needle, wherein a first wash flow pathway is vertically offset from a second wash flow pathway, such that a wash solution flows axially along an exterior surface of the sample needle in a vertical direction to wash the sample needle when flowing from the first wash flow pathway to the vertically offset second wash flow pathway, is provided. Furthermore, an autosampler and associated methods are also provided. 1. A seal pack of a sample manager of a liquid chromatography system , the seal pack comprising:a plurality of wash flow pathways fluidically connected to a central pathway that accommodates a sample needle, wherein a first wash flow pathway is vertically offset from a second wash flow pathway, such that a wash solution flows axially along an exterior surface of the sample needle in a vertical direction to wash the sample needle when flowing from the first wash flow pathway to the vertically offset second wash flow pathway.2. The seal pack of claim 1 , wherein the wash solution flows within the central pathway between the first wash flow pathway and the second wash flow pathway.3. The seal pack of claim 1 , wherein the wash solution washes the sample needle as the sample needle moves vertically within the seal pack.4. The seal pack of claim 1 , further comprising an upper body portion claim 1 , a middle portion claim 1 , and a lower body portion claim 1 , which form a general body structure of the seal pack.5. The seal pack of claim 4 , wherein the first wash flow pathway and the second wash flow pathway are both disposed within the upper body portion.6. The seal pack of claim 1 , wherein the first wash flow pathway includes a wash inlet fluidically connected to an external wash reservoir of the liquid chromatography system.7. The seal pack of claim 1 , wherein the exterior surface of ...

System and methods for monitoring leaks in underground storage tanks

Leak detection system and method for monitoring leaks in underground and aboveground storage tanks, pipelines or other containments, including single, double or triple wall containments are provided. A leak detection apparatus includes an oxidation chamber, a chemical marker concentrator, a mass spectrometer (MS) ion trap and a scroll vacuum pump. Vapor samples carrying marker chemicals introduced into a tank, pipeline, or other containment are injected at sample injection point into an oxidation chamber. Oxygen from an oxygen source is fed into oxidation chamber to destroy or oxidize contaminates such as hydrocarbons in the vapor without destroying or oxidizing the chemical markers. Effluent from the oxidation chamber is passed to an elongate conduit with a metal foil or screen suspended within the conduit. The marker chemicals are attracted by a chemical coating on the foil/screen and released by heating the metal. The released marker chemicals are fed into a mass spec ion trap for leakage analysis and results.

Pressure driven microfluidic injection for chemical separations

Methods that allow independently applied pressures to a BGE reservoir and a sample reservoir for pressure-driven injection that can inject a discrete sample plug into a separation channel that does not require voltage applied to the sample reservoir and can allow for in-channel focusing methods to be used. The methods are particularly suitable for use with a mass spectrometer.

PYROLYSIS TO DETERMINE HYDROCARBON EXPULSION EFFICIENCY OF HYDROCARBON SOURCE ROCK

Some examples of pyrolysis to determine hydrocarbon expulsion efficiency of hydrocarbon source rock can be implemented by performing an open system pyrolysis of a hydrocarbon source rock sample obtained from a natural system. Sample includes hydrocarbon source rocks having an equivalent spherical diameter of substantially at least one centimeter. After the open system pyrolysis, the sample can be crushed and thermally vaporized. A hydrocarbon expulsion efficiency of hydrocarbon source rock in the natural system can be determined based on hydrocarbons recovered in response to the open system pyrolysis and in response to the crushing and thermal vaporization. 1. A method comprising:performing an open system pyrolysis of a hydrocarbon source rock sample obtained from a natural system, the hydrocarbon source rock sample comprising hydrocarbon source rocks having an equivalent spherical diameter of substantially at least one centimeter;recovering hydrocarbons released by the hydrocarbon source rock sample in response to the open system pyrolysis;performing a thermo-vaporization on the pyrolyzed hydrocarbon source rock sample on which the open system pyrolysis was performed;recovering hydrocarbons released by the pyrolyzed hydrocarbon source rock sample in response to the thermo-vaporization; anddetermining a hydrocarbon expulsion efficiency of hydrocarbon source rock in the natural system based on the recovered hydrocarbons released by the hydrocarbon source rock sample in response to the open system pyrolysis and based on the recovered hydrocarbons released by the pyrolyzed hydrocarbon source rock sample in response to thermo-vaporization.2. The method of claim 1 , wherein the natural system comprises a subsurface system comprising a hydrocarbon reservoir.3. The method of claim 1 , further comprising crushing the pyrolyzed hydrocarbon source rock prior to performing the thermo-vaporization.4. The method of claim 1 , wherein determining the hydrocarbon expulsion ...

SAMPLE INTRODUCTION DEVICE

A sample introduction device includes a tube holding unit a tube heating unit and a movement mechanism The tube holding unit holds a sample tube The tube heating unit comes into contact with the sample tube held in the tube holding unit and heats the sample tube to desorb sample components in the sample tube The tube holding unit and the tube heating unit are attached to the movement mechanism so as to be able to move separately. The movement mechanism includes a nut which can be attached to and detached from the tube holding unit and the tube heating unit and a support shaft which supports the nut such that the nut can move. 1. A sample introduction device for heating a sample tube which contains a sample to desorb a sample component and to introduce the sample component to an analyzing unit , the device comprising:a tube holding unit which holds the sample tube;a tube heating unit which comes into contact with the sample tube held in the tube holding unit and heats the sample tube to desorb the sample component in the sample tube; anda movement mechanism to which the tube holding unit and the tube heating unit are attached such that the tube holding unit and the tube heating unit can move separately, whereinthe movement mechanism includesa connecting member which can be attached to and detached from the tube holding unit and the tube heating unit, anda support portion which supports the connecting member such that the connecting member can move.2. The sample introduction device according to claim 1 , whereinthe support portion includes a support shaft which extends in a straight line, andthe connecting member is supported by the support shaft such that the connecting member can move on a straight line along the support shaft.3. The sample introduction device according to claim 1 , wherein the connecting member includes a magnet which can be attached to and detached from the tube holding unit and the tube heating unit due to magnetic force.4. The sample ...

Method of preparing delta-9-tetrahydrocannabinol

A method of preparing tetrahydrocannabinol using extraction of plant material with a non-polar solvent followed by vacuum distillation and collection of a constant boiling fraction. Additional distillation steps and chromatographic steps, including HPLC reversed phase HPLC and flash chromatography, may be performed.

Method of preparing delta-9-tetrahydrocannabinol

A method of preparing tetrahydrocannabinol using extraction of plant material with a non-polar solvent followed by vacuum distillation and collection of a constant boiling fraction. Additional distillation steps and chromatographic steps, including HPLC, reversed phase HPLC and flash chromatography, may be performed.

Micropump

A microsized pump is set forth. It comprises a substrate which at least partially defines one or more walls of a longitudinally extending tunnel. The tunnel has a vibratable wall portion. A sonic energy generator is positioned in sonic energy transmitting relation to the vibratable wall portion. The sonic energy generator is adapted to generate elastic waves which travel along the longitudinal extension of the tunnel. The pump is useful for moving material along the tunnel whereby chemical and biological analysis and reactions can be carried out on a micro scale.

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Calibration method for pyrolysis gas chromatograph mass spectrometer

一种吡仑帕奈片有关物质的检测方法

本发明涉及一种吡仑帕奈片有关物质的检测方法，属于药物分析技术领域。本发明的检测方法采用流动相A和流动相B为混合流动相进行梯度洗脱，流动相A为水相，流动相B为有机相；梯度洗脱过程中流动相A和流动相B的初始比例为25～35:75～65或70:30；在0‑8分钟内，流动相A和流动相B的体积比保持初始比例不变；在8‑30分钟内，流动相A和流动相B的体积比由初始比例匀速渐变至40:60；在30‑40分钟内，流动相A和流动相B的体积比保持40:60不变；在40‑50分钟内，流动相A和流动相B的体积比由40:60匀速渐变至70:30；在50‑60分钟内，流动相A和流动相B的体积比保持70:30不变。

Installation for determining thermal stability of hydrocarbon oils

Изобретение относитс  к установке дл  определени  термической стабильности углеводородных масел может быть использовано в нефтехимии и позвол ет повысить достоверность анализа и снизить трудоемкость. Установка содержит пиролизер, выполненный в виде электропечи 1 с размещенными внутри нее V-образной трубкой 2. и термопарой 3, устройство дл  подачи пробы масла, выполненное в виде Y-образной трубки 4 с глухим отростком. В трубке 4 расположена стекл нна  лодочка 5 с анализируемым маслом. Трубка 2 св зана через кран-дозатрр 6 с хроматографической колонкой 7 и с хроматографом 8, имеющим детектор по теплопроводности . В хроматографе 8 помещен сосуд 9 с газом-носителем. 1 ил., 1 табл. (Л с N9 00 о сл 00 ф The invention relates to an apparatus for determining the thermal stability of hydrocarbon oils that can be used in the petrochemical industry and makes it possible to increase the reliability of the analysis and reduce the labor intensity. The installation contains a pyrolyzer, made in the form of an electric furnace 1 with a V-shaped tube 2 and a thermocouple 3 placed inside it, an oil sample supply device, made in the form of a Y-shaped tube 4 with a blind process. In tube 4 there is a glass boat 5 with oil analyzed. Tube 2 is connected via a docking cock 6 with a chromatographic column 7 and with a chromatograph 8 having a thermal conductivity detector. In the chromatograph 8 placed the vessel 9 with a carrier gas. 1 ill., 1 tab. (L with N9 00 about SL 00 f

带腔室隔膜

一种隔膜，其沿着隔膜的中心轴线包含至少一个内部腔室。该腔室提供了释放空间，当针穿过隔膜时，隔膜的密封部分可变形到该释放空间中。腔室的结合减少了隔膜和针之间的表面积接触和摩擦，从而减少了隔膜的撕裂并减少了研磨产生的颗粒物。

一种汽车内饰材料中冷凝组分定性定量测试方法

本发明公开了一种汽车内饰材料中冷凝组分定性定量测试方法，该方法通过以下步骤实现：1)将汽车内饰材料裁剪为圆形并置于起雾杯中，并且将质量为m 1 的铝箔盖于起雾杯杯口上；2)对位于起雾杯内的汽车内饰材料进行雾化处理，雾化完毕后，取下铝箔进行干燥并称重，获得质量为m 2 的冷凝后铝箔；3)确定出冷凝组分的总含量；4)采用红外光谱仪对上述冷凝后铝箔上的冷凝组分进行定性测试，获得冷凝组分的主要组成物质；5)根据上述获得的冷凝组分的主要组成物质选择对应的有机溶剂，采用有机溶剂对上述质量为m 2 的冷凝后铝箔上冷凝组分进行溶解，获得有机溶液；6)采用气相色谱与质谱联用仪对上述有机溶液中的冷凝组分进行定性定量测试。

Capillar gas chromatograph

Изобретение относитс  к области аналитического приборостроени , в частности к газовым хроматографам, использующим высокоэффективные капилл рные хроматографические колонки. Изобретение предназначено дл  анализа многокомпонентных смесей газов и жидкостей, в особенности дл  анализа микропримесей веществ в газовых и жидких смес х. Цель изобретени  - повышение точности за счет исключени  неконтролируемых потерь компонентов пробы и упрощение процесса. Адсорбционна  ловушка анализируемых веществ установлена между испарителем и делителем потока, а в трубопроводе дл  сброса части потока газа-носител  из делител  потока в атмосферу установлен управл емый запорный клапан. 1 ил. The invention relates to the field of analytical instrumentation, in particular to gas chromatographs using high performance capillary chromatographic columns. The invention is intended for the analysis of multicomponent mixtures of gases and liquids, in particular for the analysis of trace impurities of substances in gas and liquid mixtures. The purpose of the invention is to improve accuracy by eliminating uncontrolled loss of sample components and simplifying the process. An adsorption trap of the analyzed substances is installed between the evaporator and the flow divider, and a controlled shut-off valve is installed in the pipeline to discharge part of the carrier gas flow from the flow divider to the atmosphere. 1 il.

一种全氟磺酸相对分子质量及分布的分析方法

本发明公开了一种全氟磺酸相对分子质量及分布的分析方法，包括：(1)全氟磺酸待测样品溶液的制备；(2)混合标准样品溶液的配制；(3)设置色谱分析条件；(4)标准曲线的制作；(5)全氟磺酸待测样品分析。本发明具有准确、高效、重现性好和操作简单的优点。

Device for introducing liquid sample in gas chromatograph

Automatic sample injection device

Novel multiple-dimension gas phase chromatographic device and analyte conveying method using multiple cooling wire connections

本发明提供一种MDGC装置，包括一种能够冷却部分化学样品至少两次的低温捕集装置，配置有位于低温捕集器上游的检测器装置，能够识别该部分化学样品，从而控制化学样品在低温捕集装置中的停留时间。

A novel single purification column kit for simultaneously removing sulfur, water and polar organic chemical materials containing sample

본 발명은 가스크로마토그래피를 이용하여 황, 극성물질, 수분을 함유하는 시료(예, 해양퇴적물)에 존재하는 유기염소계농약(OCPs)이나 폴리클로리네이티드바이페닐(PCBs), 다환방향족탄화수소(PAHs) 등을 분석하기 위한 전처리 과정에서, 황, 극성물질 및 수분을 제거하기 위해 소요되는 수 단계의 정제 과정을 단일 과정으로 단축하여 이들을 간편하게 정제할 수 있는 컬럼정제키트에 관한 것으로서, 유리관 하단에 극성 유기물질 흡착제(예: 실리카겔, 플로리실, 알루미나 등)가 충진되고 그 위에는 무수황산나트륨(Na 2 SO 4 )과 활성 구리(Cu)의 혼합물이 충진된 것을 특징으로 하는 새로운 컬럼정제장치를 제공할 수 있다.

Device and method of hydrogen to carbon ratio determination and adjustment in liquid fraction of pyrolysis product

Группа изобретений относится к определению и регулированию отношения водорода к углероду в жидком углеводороде. Представлен способ определения отношения водорода к углероду жидкой фракции в процессе пиролиза, в котором известное количество углеводородного сырья, содержащего известное количество меченого газа, некоторое количество углерода в углеводородном сырье и некоторое количество водорода в углеводородном сырье, загружают в пиролитическую печь, работающую в условиях процесса пиролитического крекинга, для получения продукта пиролиза, в котором указанный продукт пиролиза содержит жидкую фракцию и газообразную фракцию, причем указанная жидкая фракция имеет содержание водорода и содержание углерода, чтобы тем самым получить отношение водорода к углероду жидкой фракции, и указанная газообразная фракция имеет некоторую концентрацию меченого газа в газообразной фракции, некоторое содержание водорода и некоторое содержание углерода в газообразной фракции, включающий этапы: (a) определения содержания водорода и содержания углерода в указанном углеводородном сырье; (b) определения содержания водорода и содержания углерода в указанной газообразной фракции посредством определения концентрации меченого газа в указанной газообразной фракции, использования определенной таким образом концентрации меченого газа в газообразной фракции для определения доли указанного продукта пиролиза, которая является указанной газообразной фракцией, и использования таким образом определенной доли указанного продукта пиролиза, которая является указанной газообразной фракцией, при определении содержания водорода и содержания углерода в указанной газообразной фракции и (с) определения отношения водорода к углероду указанной жидкой фракции посредством вычитания определенной величины содержания водорода в указанной газообразной фракции из определенной величины содержания водорода в указанном углеводородном сырье для получения содержания водорода в указанной жидкой фракции, вычитания определенной ...

Apparatus for, and methods of, operating upon a fluid

A filter comprises a nonporous support member open at one end and a porous disc rigidly secured to the support member at an opposite, preferably smaller, end. The disc may be formed from fibers preferably having a thickness of approximately 0.5-50 micrometers, or it may be formed from a plurality of particles or beads retained by a pair of membranes. When the disc is relatively small such as approximately 1 millimeter in diameter, it may be pressed into a constricted end of the support member. When the disc has an increased diameter, it may be rigidly supported by a retainer preferably made from a mesh material and welded to the support member. For even larger disc sizes, the disc may be supported between two (2) retainers preferably welded to the support member. A plurality of receptacles may be disposed in a tray to, serve as the filters, or receive the filters. The fluid may be introduced into, and retained in, the support members and discs by capillary action. The fluid may be passed through the filters by centrifuging the tray with the filters. The trays bearing the filters may be centered in a container to inhibit contact with the container walls and fluid vapor may be passed through the container to interact with material on the centered filters. An absorbent sheet moistened with the fluid may be positioned against the container walls to maximize vapor content within the container.

Gas chromatograph

Disclosed is a method and apparatus for injecting samples into the evaporator of a gas chromatograph effected by a sample carrier, whereafter the thus formed vapors are transferred into the flow of a carrier gas. According to one aspect of the invention, the evaporator of the gas chromatograph is sealed only for a period of the sample introduction subsequent to the physical communication of the evaporator with the sample carrier. Vapors of the substance under analysis are conveyed from the evaporator into the chromatographic column via a flow constrictor of constant cross-sectional diameter. According to another aspect of the invention the flow constrictor of constant cross-section is positioned essentially after the passageway communicating the sample carrier with the evaporator but prior to the passageway for evacuating the vapors from the evaporator to the chromatographic column. The sample carrier is provided with a sealing element for sealingly blocking the passageway communicating the sample carrier with the evaporator during sample injection.

Method for testing harmful volatile matters of non-metallic materials of passenger vehicle

本发明公开了一种乘用车非金属材料有害挥发物测试方法，所述测试方法将非金属材料装入采样袋，并配备同规格空白采样袋，通过加热使有害挥发物质从待检测的吸附物体中脱离出来，通过TENAX采样管采集苯类物质，并通过热解吸系统提取TENAX采样管内的苯类物质，导入气体色谱‑质谱仪，通过苯类物质分析曲线获得各苯类物质的定量值，通过DNPH采样管采集醛酮类物质，并通过乙腈洗脱DNPH采样管制成醛酮类物质试剂，导入高效液相色谱仪‑二极管阵列检测器，通过醛酮类物质分析曲线获得各醛酮类物质的定量值，最终计算获得个有害挥发物质浓度。本发明通过检测各非金属材料中挥发出有害物质浓度，进而锁定不合格车内饰总成，实现有针对性的改进。

Quantitative analysis method of monomers in binders of photoresists

본 발명은 박막 트랜지스터 액정표시장치(thin film transistor-liquid crystal display, TFT-LCD)용 칼라필터(color filter, CF) 감광재 바인더(photoresist(PR) binder)의 모노머(monomer) 정량분석방법에 관한 것으로, 정성분석에 활용하였던 Py-GC/MS를 이용하여 TFT-LCD용 칼라필터 감광재(PR) 바인더의 모노머를 정량분석할 수 있었다.

Method for determining content of K powder in human hair by flash evaporation-gas chromatography-mass spectrometry

本发明提供了一种利用闪蒸‑气相色谱质谱法测定人体毛发中K粉含量的方法，与现有技术相比，本发明无需复杂的样品前处理过程，开发的闪蒸‑气相色谱质谱法操作简便、环保，能够有效节约分析时间、简化实验步骤，本发明消耗的样品量少，一次处理仅需一根毛发(0.3mg)，能够大大减低取样的难度，本发明开发的方法可适用于分析人体毛发中氯胺酮的含量，对吸食毒品和药物滥用的监控具有十分深远的意义。

System, apparatus and method for monitoring organic compounds in a gaseous medium

Изобретение относится к системе и устройству микромониторинга. Система для анализа по меньшей мере одного химического соединения в газовой смеси, содержащая: пробоотборный вход; фильтр; ловушку; хроматографическую колонку; детектор; и насос, причем пробоотборный вход, ловушка и насос соединены по текучей среде с образованием первого пути потока газа, в котором насос расположен ниже пробоотборного входа и ловушки по ходу потока, причем пробоотборный вход, фильтр, ловушка, хроматографическая колонка, детектор и насос соединены по текучей среде с образованием второго пути потока газа, в котором насос расположен ниже всех указанных компонентов по ходу потока, при этом газовая смесь представляет собой воздух. Технический результат - повышение эффективности определения органических соединений в газовых средах без использования сжатого газа. 2 н. и 16 з.п. ф-лы, 15 ил. РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 2 733 529 C2 (51) МПК G01N 1/00 (2006.01) G01N 7/00 (2006.01) G01N 9/00 (2006.01) G01N 19/10 (2006.01) G01N 25/00 (2006.01) G01N 27/00 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ОПИСАНИЕ ИЗОБРЕТЕНИЯ К ПАТЕНТУ (52) СПК G01N 1/00 (2020.05); G01N 7/00 (2020.05); G01N 9/00 (2020.05); G01N 19/10 (2020.05); G01N 25/00 (2020.05); G01N 27/00 (2020.05) (21)(22) Заявка: 2018139275, 14.04.2017 14.04.2017 (73) Патентообладатель(и): ЙЕЛЬСКИЙ УНИВЕРСИТЕТ (US) Дата регистрации: 02.10.2020 Приоритет(ы): (30) Конвенционный приоритет: 15.04.2016 US 62/322,980 (43) Дата публикации заявки: 15.05.2020 Бюл. № 14 (45) Опубликовано: 02.10.2020 Бюл. № 28 (86) Заявка PCT: US 2017/027523 (14.04.2017) C 2 C 2 (85) Дата начала рассмотрения заявки PCT на национальной фазе: 15.11.2018 (87) Публикация заявки PCT: 2 7 3 3 5 2 9 WO 2017/180933 (19.10.2017) R U 2 7 3 3 5 2 9 (56) Список документов, цитированных в отчете о поиске: US 8347688 B2, 08.01.2013. US 8230719 B2, 31.07.2012. US 6460401 B1, 08.10.2002. RU 2009144885 A, 10.06.2011. R U (24) Дата начала отсчета срока ...

Improved Recovery of Organic Compounds in Liquid Samples Using Full Evaporative Vacuum Extraction, Thermal Desorption, and GCMS Analysis

吸着剤を含む試料抽出装置が、試料を含有する試料バイアルに結合されている間に、試料抽出装置を通して真空引きして試料の揮発性マトリックスを蒸発させ、試料の揮発した標的化合物を吸着剤に搬送する。随意に、揮発性マトリックスが蒸発すると、試料バイアルが加熱され、及び／又は真空レベルが高められ、より重い標的化合物を吸着剤へと移送する。複数のサンプリング装置が、並行して抽出され得る。試料抽出装置は、試料抽出装置をガスクロマトグラフに直接結合する熱脱着装置に挿入することができる。いくつかの実施形態では、試料は、ガスクロマトグラフィ又は別の好適な技法を使用して脱着及び分析される。本明細書に開示される技術は、水、食品、飲料、土、及び他のマトリックス中の揮発性有機化合物及び半揮発性有機化合物の分析に使用される。

Apparatus and method for determining and controlling the hydrogen-to-carbon ratio of a pyrolysis

一种用于测定热解产物液体馏分的氢－碳比的方法及装置，其通过测定热解产物气体馏分的氢－碳比，再从所测得的热解炉烃进料的氢－碳比中减去上述所测得的值。使用所测得的液体馏分的氢－碳比的值作为裂解度的量度并用于热解炉响应于液体馏分所需的与实际的氢－碳比之间的差值的控制。

Method and apparatus for testing coal coking properties

A method of testing the coking qualities of sample quantities of coal in a test container and the structure of the test container are disclosed. A test container which is ideally reusable is adapted to receive one or more samples of coal to be tested and then the test container is inserted into a coking oven along with additional, conventional coal during a conventional coking operation. Following the completion or substantial completion of the coking operation, the test container is recovered and from the conventional converted coke and the sample(s) of coke are removed from the container for testing and evaluation. The container is recharged with one or more additional samples of coke and reused in another conventional coking operation.

Flow control system and comprise the monitoring device for detecting airborne analysis thing of described flow control system

在此披露了一种用于维持稳定空气流量的流量调节系统，该流量调节系统包括至少一个泵、一个质量流量传感器、一个环境温度传感器、一个环境压力传感器、一个测量所述质量流量传感器的温度的温度补偿传感器，以及一个控制系统；以及一种用于使用所述流量调节系统来测量流量的方法；一种用于监测同时以气相和颗粒相存在于空气中的空气传播化合物的装置，其中该装置包括一个取样装置、一个浓缩捕集器1、一个校准调谐模块、一个空模块、所述流量调节系统、一个色谱单元，以及一个检测单元；以及一种通过使用所述监测装置来检测空气流中的空气传播化合物的方法。

Flow regulating system and monitoring device comprising said flow regulating system for the detection of air borne analytes

적어도 하나의 펌프, 질량 유량 센서, 주위 온도 센서, 주위 압력 센서, 상기 질량 유량 센서의 온도를 측정하는 온도 보정 센서, 및 제어 시스템을 포함하는 안정된 공기 흐름을 유지하기 위한 유량 조절 시스템, 뿐만 아니라 상기 유량 조절 시스템을 이용하여 유량을 측정하는 방법, 샘플링 장치, 농축 트랩(1), 보정 및 조정 모듈, 블랭크 모듈, 상기 유량 조절 시스템, 크로마토그래피 유닛, 및 검출 유닛을 포함하는, 공기 중에 기상 및 입자상으로 존재하는 공중 화합물들의 모니터링 장치, 및 상기 모니터링 장치를 이용하여 공기 흐름 내 공중 화합물들을 검출하는 방법이 개시된다. A flow control system for maintaining a stable air flow including at least one pump, a mass flow sensor, an ambient temperature sensor, an ambient pressure sensor, a temperature correction sensor for measuring the temperature of the mass flow sensor, and a control system, A method for measuring a flow rate using a flow rate control system, comprising the steps of: measuring a gas phase and a particulate phase in the air, comprising a sampling device, a concentration trap (1), a calibration and adjustment module, a blank module, A method for monitoring public compounds in an air stream using the monitoring device, and a method for detecting air compounds in an air flow.

Hybrid capillary/filled trap and method of use

Preparation method and application of load-controllable strong-cation solid-phase extraction filler

本发明涉及一种担载量可控的强阳离子固相萃取填料的制备方法及应用，其结构式如图。以含有苯环结构的聚合物为反应物，选择不同的磺化剂，采用表面修饰法一步制备固相萃取填料。该固相萃取填料具有担载量可控、比表面积大、富集效率高、制备简单和节约成本等优点。本发明制备的固相萃取填料适用于动物源食品中β‑受体激动剂的检测前处理工作，具有良好的经济和社会效益。 图1一种强阳离子固相萃取填料的结构示意图其中，

Analyte pre-concentrator for gas chromatography

An analyte pre-concentrator for gas chromatography is disclosed generally comprising a tube having a restricted outlet and packed with an adsorbent, wherein the tube serves as the liner of a chromatographic injector, as an adsorbent trap coupled to a chromatographic column, and/or as an adsorbent trap coupled to a headspace sampler. Preferably, a heating device allows the tube to be heated. In a preferred embodiment, the analyte pre-concentrator further comprises a column isolating accessory so that a chromatographic column can be temporarily isolated from substances flowing through the tube.

System and method for extracting headspace vapor

A system and method for extracting headspace vapor is generally disclosed comprising pressurizing a vessel containing headspace vapor with a carrier gas and subsequently venting the sample mixture through an adsorbent trap and out a vent. A flow controller is employed to gradually regulate the flow therethrough as the pressure drops as a result of the gradual depletion of headspace vapor in the vessel and, in certain embodiments, the flow controller maintains a constant flow rate. Due to the time saved, in some embodiments, multiple pressurization-venting cycles are implemented to maximize the amount of vapor extracted from the vial. Due to the constant flow rate, in certain embodiments, the pressure decay is monitored and compared to reference values in order to determine whether the sample vessel has a leak or other defect.

Application of double-positive imidazolium salt ionic liquid in extraction of bisphenol compounds and micro-extraction technology based on ionic liquid

本发明提供了双阳性咪唑盐离子液体在双酚类化合物萃取中的应用，双阳性咪唑盐类离子包括[C 4 (MIM) 2 ]Br 2 和[C 6 (MIM) 2 ]Br 2 中的一种或组合。此外还提供了一种基于双阳性咪唑盐离子液体的微萃取技术，提取剂为具有双个咪唑环的双阳性咪唑盐类离子液体。萃取过程为先将待萃取基质后加入离心管中并进行稀释，再将提取剂加入所述离心管中得到混合液体，调节混合液体的PH至2～6；接着，在混合液体中加入LiNTf 2 并进行超声处理；最后将混合液体冷却并进行离心处理，获得沉降物后即完成萃取。本发明所示的微萃取方法具有操作简便，省时高效，绿色环保的优点。并且方法的线性范围宽，重现性好，检测限低，适合于复杂基质中双酚类化合物的检测分析。

Method for measuring content of toxic substances and metabolites thereof in sewage

本发明公开了一种测定污水中毒品及其代谢物含量的方法，包括以下步骤：步骤1，调节污水检材样品的pH值至小于2，过滤杂质待分析用；步骤2，固相萃取：萃取前依次利用甲醇、超纯水活化固相萃取柱，混合氘代内标工作溶液与待测样品混匀后，转移至固相萃取柱中，用超纯水淋洗，真空抽固相萃取柱，用5％氨甲醇溶液洗脱，真空抽固相萃取柱，收集洗脱液；将洗脱液吹至近干，加入0.1％甲酸水溶液混匀，用0.22μm尼龙微孔滤膜过滤，作为检材样品提取液，供仪器检测；步骤3，将检材样品提取液进行液相色谱‑串联质谱分析，检测各毒品及其代谢物的含量。本发明基本包括现有案例中的所涉及的各种毒品，以满足实际工作的需要。

detection device and detection method

本发明公开了一种检测设备和检测方法。检测设备包括：采样装置，用于采集将要被检测的样品；预处理进样装置，用于对来自采样装置的样品预处理；样品分析装置，用于分离来自预处理进样装置的被预处理的样品和分析分离后的样品。本发明的检测设备实现小型化，并且能够在不开包的情况下快速准确地检测气相物质或颗粒物质，精确度高，适于机场、口岸、地铁站等安检。

Method for detecting capsaicin compounds in duck neck

本发明公开了一种检测鸭脖中辣椒素类化合物含量的方法，包括以下步骤：提取鸭脖中的辣椒素类化合物，得到提取液；向提取液中加入由石墨化炭黑、十八烷基硅烷键合硅胶、氨丙基键合硅胶组成的净化材料，混合均匀后进行离心，离心液经微孔滤膜过滤；所得滤液利用高效液相色谱法进行检测，即可检测出鸭脖中辣椒素类化合物含量；在检测之前利用由石墨化炭黑、十八烷基硅烷键合硅胶、氨丙基键合硅胶组成的净化材料对提取液进行净化处理，以选择性吸附提取液中的色素、脂肪等杂质；此种净化方法可有效降低检测成本，有效提高检测效率，结果稳定性强，回收率高。

Gas analyzer and gas analysis method

Focusing device based on bonded plate structures

The invention provides a low mass and size thermal focusing device for a gas phase analytical device. The device has two or more plates bonded together. The device also has at least one channel with an entrance and exit is formed within allowing ingress and egress of a gas stream. The device also has a temperature reduction module in thermal contact with at least one plate of the device. Thermal focusing devices with additional plates and/or channels are also disclosed.

The quantitative analysis method of ethylidene norborene in ethylene propylene diene monomer using pyrolyzer gaschromatography massspectrometer

PURPOSE: A calculation method of ethylidene norbornene in an ethylene propylene diene monomer rubber material is provided to reliably calculate the content of ethylene propylene copolymer by implementing one time analysis. CONSTITUTION: A calculation method of ethylidene norbornene with a double bond in an ethylene propylene diene monomer rubber material includes the following steps: the characterized peak of diene monomer with a double bond by comparing the spectrum of ethylene propylene copolymer and ethylene propylene diene monomer displayed by a pyrolysis gas chromatography analysis method; and a calibration curve is deduced by analysis spectrum result for each ethylene propylene diene monomer, and the content of diene monomer with a double bond is quantified.

Gas chromatography sampling device and gas chromatograph

本申请涉及一种气相色谱进样装置及气相色谱仪，其中气相色谱进样装置包括：进样口主体，所述进样口主体上安装有支撑套，所述支撑套的内部连接有导流芯柱；所述进样口主体的内部设置有衬管，所述衬管的至少一部分伸入所述导流芯柱的导流腔室，所述支撑套、所述导流芯柱以及所述衬管之间分别设置有间隙，所述导流芯柱的顶部与所述支撑套之间设置有吹扫气流腔室；所述支撑套的侧壁上分别设置有载气入口及隔垫吹扫出口，所述载气入口及所述隔垫吹扫出口分别与所述导流腔室及所述吹扫气流腔室相通；通入载气由所述载气入口进入所述导流腔室并引流至所述衬管的上部外侧，吹扫载气由所述吹扫气流腔室通过所述隔垫吹扫出口向外排出。

Gas chromatograph

Изобретение относрРтс  к газовому анализу микропримесей в воздухе. Целью изобретени   вл етс  повышение эффективности разделени  микропримесей за счет уменьшени  размывани  фронта раздел емых веществ и уменьшени  мертвых объемов.. Устройство содержит источник газа-носител ,кран- переключатель, испаритель с двум  камерами испарени , разделительную колонку и детектор, обогатительную колонку, установленную в одной из камер испарени , причем кран-переключатель установлен между выходами из обеих камер испарени  и входом в разделительную колонку так,что он или соедин ет выход первой камеры с разделительной колонкой, или соеди- н ё-т обе камеры последовательно и выход второй камеры испарени  с разделительной колонкой. 2 ил. С (Л ND ГчЭ 05 00 The invention relates to gas analysis of trace contaminants in the air. The aim of the invention is to increase the efficiency of separation of microimpurities by reducing the smearing of the front of the substances to be separated and the reduction of dead volumes. The device contains a source of carrier gas, a faucet-switch, a vaporizer with two evaporation chambers, a separation column and a concentrator installed in one from the evaporation chambers, the tap-switch being installed between the outlets from both evaporation chambers and the entrance to the separation column so that it either connects the output of the first chamber with column-inflammatory or soedi- n g t-two chambers in series and the output of the second evaporation chamber with the separation column. 2 Il. C (L ND GcE 05 00

Sample collection and thermal desorption sampling device and method and trace detection equipment

本发明提供了一种样品采集和热解析进样装置，包括：样品采集结构；活塞式吸附器，具有能够与样品采集结构连通的用于吸附所采集的样品的吸附腔；活塞缸，限定用于容纳该吸附器并与吸附腔连通的活塞腔；热解析腔，与吸附腔和活塞腔连通并热解析被吸附在吸附腔内的样品；和泵，通过导管与活塞腔连通并通过样品采集结构将环境气体中的样品抽吸到吸附腔，所述吸附器被构造成能够在样品采集位置和样品解析位置之间在活塞腔内移动，在采集位置中吸附腔定位在热解析腔外并与样品采集结构连通以吸附由其采集的样品，在解析位置中吸附腔定位在热解析腔内使所吸附的样品在热解析腔内被热解析。还提供了采用上述装置进行样品采集和解析的方法和痕量检测设备。

Detection method for nano-plastic in biological tissue

本发明公开了一种用于生物组织中纳塑料的检测方法，属于纳塑料分析领域。该方法包括以下步骤：(1)采用碱消化法对水生动物组织进行消解；(2)采用蛋白质沉淀法使步骤(1)所得消解液中具有提取的纳塑料的蛋白质沉淀；(3)采用裂解气相色谱‑质谱法对步骤(2)所得沉淀进行定量分析。本发明实现了对复杂生物组织中纳塑料进行成分鉴定和质量定量。在优化后的碱种类及浓度等条件下，采用本方法对聚苯乙烯(PS)纳米塑料和聚甲基丙烯酸甲酯(PMMA)纳米塑料的检测限分别为0.03μg/g和0.09μg/g。该方法还保持了纳米塑料的原始形态和尺寸，具有重现性好，灵敏度高的优点，可用于多种纳塑料的定量分析。

Method for identifying pharmacodynamic components of traditional Chinese medicine based on knocking out target components and application

本发明公开了一种基于目标成分敲出的中药药效组分辨识的方法及应用，属于制药技术、药物筛选领域。所述的方法包括提取中药化学成分，敲出目标成分制备不同组分群，鉴定敲出成分评价敲出效果，量化敲出成分真实还原不同组分群在中药中的比例，确定主要药效组分群。本发明制备并筛选出具有抗白血病效应的青黛提取物敲出组分。为后续的青黛质量控制、抗白血病的药效研究及药物制剂提供基础支持，对于其它药物同样具有借鉴和推广价值。

Methods of collecting and analyzing human breath

Method for separating monocyclic, bicyclic, tricyclic and polycyclic aromatic hydrocarbons from high-sulfur crude oil

本发明属于石油化工分析实验技术领域，公开了一种高硫原油单环、双环、三环和多环芳烃分离方法，所述原油单环芳烃、双环芳烃、三环芳烃和多环芳烃分离方法包括：实验前准备工作；高硫原油四组分分离；高硫原油中芳香烃分离。本发明提供的高硫原油单环、双环、三环和多环芳烃分离方法，采用实验常用的小型氧化铝柱层析方法，使用正己烷和二氯甲烷的不同配比溶剂分离出不同环数芳香烃化合物。同时，本发明还包括以下创新点：1)实验器具和试剂在地球化学实验室易得、操作简单高效且经济成本低；2)独特的分离方法非常适用于高硫原油的芳香烃不同环数化合物的分离；3)创新了三环芳香烃的精确分离方法。