Поиск патентов

Настройки

Глубина выборки

Укажите год

Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

Подробнее

Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

Подробнее

Форма поиска

Ключевые слова. Может быть несколько по одной на строку

Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка

Автор

Ведите корректный номера.

Владелец

Ведите корректный номера.

Классы IPC

Ведите корректный номера.

Классы CPC

Ведите корректный номера.

Начиная с года

Укажите год

Заканчивая годом

Укажите год

Применить Всего найдено 22687. Отображено 100.

05-01-2012 дата публикации

Instrument for cassette for sample preparation

Номер: US20120003631A1

Автор: David Hsiang Hu, Jesus Ching, Phillip You Fai Lee, Steve Jia Chang Yu

Принадлежит: GENTURADX Inc

A parallel processing system for processing samples is described. In one embodiment, the parallel processing system includes an instrument interface parallel controller to control a tray motor driving system, a close-loop heater control and detection system, a magnetic particle transfer system, a reagent release system, a reagent pre-mix pumping system and a wash buffer pumping system.

Подробнее

Номер записи: 1

05-01-2012 дата публикации

Portable sample analyzer cartridge

Номер: US20120003730A1

Автор: Aravind Padmanabhan, Cleopatra Cabuz, James A. Cox

Принадлежит: Honeywell International Inc

A sample analyzer cartridge for use at a point of care of a patient such as in a doctor's office, in the home, or elsewhere in the field. By providing a removable and/or disposable cartridge with all of the needed reagents and/or fluids, the sample analyzer can be reliably used outside of the laboratory environment, with little or no specialized training.

Подробнее

Номер записи: 2

05-01-2012 дата публикации

Automated calibration method and system for a diagnostic analyzer

Номер: US20120005150A1

Автор: Jeremy Hammond

Принадлежит: Idexx Laboratories Inc

A method to track stability and performance of diagnostic instrumentation, especially for veterinary automated hematology analyzers, applies a weighted moving averages algorithm to the diagnostic results of patient samples calculated by the analyzer. Control chart rules are used to set limits or ranges in order to determine if weighted averaged diagnostic results are within or outside of such limits or ranges. If the weighted average diagnostic results are outside of such control chart rule limits, then fuzzy logic and a gradient descent algorithm are applied to the weighted averaged diagnostic results.

Подробнее

Номер записи: 3

19-01-2012 дата публикации

Method for operating an analytical apparatus

Номер: US20120015447A1

Автор: Oliver Bettmann, Ulrich Kathe

Принадлежит: Endress and Hauser Conducta Gesellschaft fuer Mess und Regeltechnik mbH and Co KG

A method for operating an analytical apparatus for determining concentration of an analyte, especially an oxidizable substance, in a sample liquid, comprises the steps of: placing the analytical apparatus in maintenance operation; operating a metering system, which includes a pump, especially a peristaltic pump, and a supply line, for metering single volume units of a sample liquid from a source via the supply line into a reactor, wherein there exists in the reactor a temperature, which is greater than the boiling temperature of the sample liquid, so that a volume unit of the sample liquid metered into the reactor transforms at least partially into the gas phase following entry into the reactor, especially due to heat transfer from contact with a surface within the reactor, especially directly after contact with the surface within the reactor, and wherein a carrier gas is flowing through the reactor; registering at least one measuring transducer signal for detection of the transforming of the volume unit of the sample liquid into the gas phase, and deriving, with application of the measuring transducer signal, a signal correlated with an instantaneous operating state of the metering system.

Подробнее

Номер записи: 4

26-01-2012 дата публикации

Mechanical holder for surface analysis

Номер: US20120018629A1

Автор: Christopher Alpha, Daniel Eikel, Jason Scott Vega, John D. Henion

Принадлежит: Advion Biosystems Inc

A mechanical holder that provides for a confined sampling region for extraction and removal of chemical substances contained in a dried blood spot or other spot of sample is described herein.

Подробнее

Номер записи: 5

26-01-2012 дата публикации

Belt Agitation System For Culture Bottles

Номер: US20120021452A1

Автор: James C. Bishop

Принадлежит: Biomerieux Inc

A specimen culture container agitation assembly includes an endless belt having a multitude of container-receiving clips attached thereto, each of which is adapted for retaining a specimen culture container to the belt. The belt is oriented vertically. The assembly further includes upper and lower pulleys over which the belt is driven. A drive motor drives the belt around the pulleys. Agitation of the specimen culture container is achieved by rotation of the belt over the pulleys and the retaining of the specimen culture container by the clip.

Подробнее

Номер записи: 6

08-03-2012 дата публикации

In situ heat induced antigen recovery and staining method

Номер: US20120058570A1

Автор: Lee Angros

Принадлежит: Individual

An automated in situ heat induced antigen recovery and staining method and apparatus for treating a plurality of microscope slides. The process of heat induced antigen recovery and the process of staining the biological sample on the microscope slide are conducted in the same apparatus, wherein the microscope slides do not need to be physically removed from one apparatus to another. The reaction conditions for treating a slide can preferably be controlled independently, including the individualized application of reagents to each slide and the individualized treatment of each slide.

Подробнее

Номер записи: 7

22-03-2012 дата публикации

Analyzer Assembly Platform

Номер: US20120067801A1

Автор: Harald Ferihumer, Marcel Kaeppeli, Raymond Ochsenbein, Roland Bernet

Принадлежит: Roche Molecular Systems Inc

A method for mounting and combination of an analytical apparatus with a platform for mounting such an apparatus comprising at least two units, and a platform on which said apparatus is mounted is disclosed, said platform comprising at least one platform element, and multiple feet for placing the platform elements on a surface. The feet are individually adjustable in height.

Подробнее

Номер записи: 8

05-04-2012 дата публикации

Automatic analyzer with the function of rendering reagent information unreadable

Номер: US20120080516A1

Автор: Teruhiro Yamano, Yoshimitsu Takagi

Принадлежит: Hitachi High Technologies Corp

The invention provides an automatic analyzer suitable for efficient reagent management. The analyzer allows continued use of existing reagent information storage media because reagent ID information that is no longer needed is overwritten so that it is unrecognizable to any analyzer. The invention relates to a method for automatically analyzing particular properties of an analyte by putting the analyte and a reagent into a vessel and measuring the reacted analyte-reagent mixture. The analyzer of the invention comprises: an information reader/writer for reading or writing regent information to/from storage media attached to reagent vessels; means for managing reagent information read from the storage media; means for processing reagents based on the managed information; and means for overwriting reagent information that has been judged unnecessary based on the managed information so that the unnecessary information is unrecognizable to any analyzer.

Подробнее

Номер записи: 9

03-05-2012 дата публикации

Encapsulated reagents and methods of use

Номер: US20120107834A1

Автор: Lee H. Angros

Принадлежит: Individual

The present invention contemplates use of encapsulated aqueous and non-aqueous reagents, solutions and solvents and their use in laboratory procedures. These encapsulated aqueous or non-aqueous reagents, solutions and solvents can be completely contained or encapsulated in microcapsules or nanocapsules that can be added to an aqueous or non-aqueous carrier solution or liquid required for medical and research laboratory testing of biological or non-biological specimens.

Подробнее

Номер записи: 10

03-05-2012 дата публикации

Analysis reagent and analysis device having the analysis reagent carried therein

Номер: US20120107850A1

Автор: Hiroshi Saiki, Kenji Ishibashi, Kenji Watanabe, Kouzou Tagashira, Yuki Maruyama

Принадлежит: Panasonic Corp

A reagent including a combination of a polyanionic compound and a bivalent cationic compound contains one substance selected from the group consisting of succinic acid, gluconic acid, alanine, glycine, valine, histidine, maltitol, and mannitol or at least one compound of the substance. A dry state of the reagent and deliquescence can be improved.

Подробнее

Номер записи: 11

17-05-2012 дата публикации

Apparatus and method for separating and isolating components of a biological fluid

Номер: US20120122649A1

Автор: Brian K. Cinquini, John R. Chapman, Phillip D. Kingsley, Vijay Kumar

Принадлежит: Individual

A device for separating and isolating components of a biological fluid comprising a container for containing the fluid to be processed, a tube cap assembly for closing the container while providing filling and extraction communication therewith, a float assembly disposed within the container for funneling and controlling biological fluid flow into an inverted domed shaped isolation chamber within the float and controlling the biological fluid flow out of the isolation chamber for effecting an encapsulation or a sealed isolation of at least one component or fraction of the biological fluid flow within the isolation chamber during a centrifugation process. The device further comprising a flexible tube for connecting an extraction passageway disposed within the float assembly and an extraction valve of the tube cap assembly for allowing extraction of at least the one component or fraction encapsulated or isolated within the chamber.

Подробнее

Номер записи: 12

24-05-2012 дата публикации

Automatic analyzer

Номер: US20120128534A1

Автор: Takuya Yamaguchi, Yusuke Minemura

Принадлежит: Hitachi High Technologies Corp

An automatic analyzer has a noncontact identification medium with an antenna, a communication device for communicating with the noncontact identification medium, a container for containing a liquid, and a container holding mechanism in which the container is to be placed, the antenna being placed in an asymmetric position relative to the container. The automatic analyzer includes an identification mechanism. When the noncontact identification medium provided for the container cannot communicate with the communication device, the identification mechanism moves the container a predetermined distance by driving the container holding mechanism, causes the noncontact identification medium to communicate with the communication device, and identifies an orientation of the container placed in the container holding mechanism.

Подробнее

Номер записи: 13

24-05-2012 дата публикации

Sample analyzer

Номер: US20120129247A1

Автор: Eiji Hama, Eiji Tanoshima, Naohiko Matsuo

Принадлежит: Sysmex Corp

A sample analyzer for analyzing a sample with a liquid in a container is disclosed. The sample analyzer comprises: a reader that reads an information of a liquid in a container, the information of the liquid being stored in a storage medium; a display; and a controller including a processor and a memory under control of the processor, the memory storing instruction causing the processor to carry out operations comprising: determining whether the sample analyzer is ready to read the information of the liquid by the reader; and causing, when the sample analyzer is determined to be ready, the display to display an indication that indicates the sample analyzer is ready to read the information of the liquid by the reader.

Подробнее

Номер записи: 14

24-05-2012 дата публикации

Centrifugal separator

Номер: US20120129673A1

Автор: Hiroshi Oga, Kuniaki Onizawa, Shigemi Oba, Tatsuya Fukugaki, Tetsuya Isobe

Принадлежит: Hitachi High Technologies Corp

The weight difference is limited between buckets ( 17 ) mounted at respective symmetrical positions with respect to a centrifugal separation rotational center and examination of samples is continuously performed in the order in which they are received. In particular, when a sample ( 21 ) is carried in a centrifugal buffer line ( 11 ), its weight is measured by weight measuring means ( 31 ). It is assumed that the names of two adaptors ( 22 ) placed at respective symmetrical positions with respect to the centrifugal separation rotational center are defined as an adaptor A and an adaptor B. A first sample is put on the adaptor A and a second sample is put on the adaptor B. Then, a third sample and subsequent ones are each put on the adaptor ( 22 ) lighter than the other adaptor after the total weights of samples put on the adaptors are computation-compared with each other.

Подробнее

Номер записи: 15

31-05-2012 дата публикации

Article conveying system and sample processing system

Номер: US20120133492A1

Автор: Kuniaki Onizawa, Shigemi Oba, Tatsuya Fukugaki, Yoshio Kiyonari

Принадлежит: Hitachi High Technologies Corp

An object of the present invention is to provide a sample processing system, wherein writing to each RFID is equalized to eliminate unevenness in the use of sample containers. The configuration of the present invention can be realized by controlling the numbers of times (write counts) data is written to RFIDs, and by skipping data writing according to frequencies in the use of sample containers. Setting use information (count) of each IC tag, and comparing the use information with an average value of the use of the IC tags, make it possible to limit the write counts, which enables the equalization of writing to the IC tags, thereby making it possible to uniform the use of the sample containers in the system.

Подробнее

Номер записи: 16

31-05-2012 дата публикации

Specimen processing system

Номер: US20120134895A1

Автор: Izumi Waki, Katsuhiro Kanda, Makoto Nogami

Принадлежит: Hitachi High Technologies Corp

Disclosed is a specimen processing system that includes means 91 circularly disposed to carry a reaction vessel 2 used for separating and extracting desired substances from a specimen to be processed, a plurality of processing steps, executed as processing progresses along a transport line for the reaction vessel 2 on the transport means 91, for conducting various processes upon the specimen to be processed that is accommodated in the reaction vessel 2, suctioning and discharging means 94 that dispenses the specimen from a specimen container 1 supplied to the system, into the reaction vessel 2, and a filtering vessel section 2 b provided as a part of the reaction vessel 2. This system configuration allows realization of a rapid preprocessing system capable of reducing the number of disposable parts of a low carry-over type, suppressing a decrease in cost performance, operating with high collection efficiency, and employing compact devices.

Подробнее

Номер записи: 17

31-05-2012 дата публикации

Variable Volume Mixing and Automatic Fluid Management for Programmable Microfluids

Номер: US20120136492A1

Автор: Ahmed Mohamed Eid Amin, Han-Sheng Chuang, Mithuna Shamabhat Thottethodi, Stephen C. Jacobson, Steven T. Wereley, Terani Nadadoor Vijaykumar

Принадлежит: PURDUE RESEARCH FOUNDATION

A microfluidic arrangement including a fluid channel configured to receive a first fluid from a first inlet and a second fluid from a second inlet, and a mixer connected to the fluid channel, the mixer including a mixer channel configured to receive a volume of the first fluid and a volume of the second fluid from the fluid channel, the mixer channel defining a mixer capacity, wherein the mixer is (i) configured to mix the volume of the first fluid and the volume of the second fluid in order to provide a mixture of the first fluid and the second fluid when the combined volume of the first fluid and the second fluid is less than the mixer capacity, and (ii) further configured to mix the volume of the first fluid and the volume of the second fluid in order to provide a mixture of the first fluid and the second fluid when the combined volume of the first fluid and the second fluid is equal to the mixer capacity.

Подробнее

Номер записи: 18

07-06-2012 дата публикации

Method for producing a reagent container assembly and reagent container assembly

Номер: US20120141339A1

Автор: Reinhold Kraemer, Stephan Sattler

Принадлежит: Roche Diagnostics Operations Inc

Embodiments directed to a process for producing a reagent container assembly made of plastic and a reagent container assembly are disclosed. The process may comprise: assembling a group of particular reagent containers, and joining the reagent containers to form the reagent container assembly where at least two of the reagent containers are permanently joined together by at least one welding process.

Подробнее

Номер записи: 19

14-06-2012 дата публикации

Specimen processing device, specimen conveyance device, and specimen conveyance method

Номер: US20120148447A1

Автор: Hiroyuki Tanaka

Принадлежит: Sysmex Corp

A specimen processing device comprising: a specimen processing unit for processing specimens; a first conveyance mechanism for conveying specimens from a carry-in side towards a carry-out side on the opposite side of the carry-in side with respect to the specimen processing unit through a specimen supply position for supplying specimens to the specimen processing unit; a second conveyance mechanism for conveying specimens from the carry-in side towards the carry-out side without passing the specimen supply position; a first control device for controlling the first conveyance mechanism; and a second control device for controlling the second conveyance mechanism, is disclosed. A specimen conveyance device and a specimen conveyance method are also disclosed.

Подробнее

Номер записи: 20

21-06-2012 дата публикации

Liquid feeding system for microchip, sample detection device, and liquid feeding method for liquid feeding system for microchip

Номер: US20120156800A1

Автор: Kusunoki Higashino, Naoki Hikage, Youichi Aoki

Принадлежит: KONICA MINOLTA INC

A liquid feeding system for a microchip performs: a first liquid feeding step in which a sample liquid in a sample liquid containing section is fed in the direction to a primary containing section via a reaction field; a second liquid feeding step in which, after the first liquid feeding step, the sample liquid is fed from the primary containing section in the direction to the reaction field; and a third liquid feeding step in which, after the second liquid feeding step, the feedings of the sample liquid from and to the reaction field and the primary containing section a rear side gas-liquid boundary face of the sample liquid in the first liquid feeding step and the front side and rear side gas-liquid boundary faces of the sample liquid in the second and third liquid feeding steps do not pass through the reaction field.

Подробнее

Номер записи: 21

28-06-2012 дата публикации

Drive assembly for robotic conveyor system

Номер: US20120163945A1

Автор: John E. Lillig, Rhett L. Affleck, Robert K. Neeper

Принадлежит: Brooks Automation Inc

A storage and retrieval system is provided. The storage and retrieval system having a frame and a shuttle movable within the frame, the shuttle having a carriage extending at least partially between a top and bottom of the frame. At least one tension member extends between a first and second ends of the frame and is coupled to the shuttle. At least one drive member extends between the first and second ends of the frame and is coupled to the shuttle. The at least one drive member and the at least one tension member project from opposite sides of the shuttle towards respective first and second ends of the frame and effect stabilization of the carriage against at least rotation relative to the frame. The at least one tension member crosses the at least one drive member and the at least one drive member effects movement of the shuttle.

Подробнее

Номер записи: 22

28-06-2012 дата публикации

Sample Distribution

Номер: US20120164735A1

Автор: Andreas Gisler, Heinz Trueeb, Paul Frank, Robert Huesler, Rolf Knobel, Siegfried Mueller, Urs Schnieper

Принадлежит: Roche Molecular Systems Inc

A method is described for distributing samples within an automated analyzer from a linear arrangement of sample vessels to a processing plate in a two-dimensional n×m arrangement wherein samples are sorted, followed by transfer with a pipetting device with a linear arrangement to a processing vessel in a two-dimensional n×m arrangement and subsequent processing of samples using a second pipetting device which has a two-dimensional n×m arrangement.

Подробнее

Номер записи: 23

12-07-2012 дата публикации

Automated sample processing system

Номер: US20120174687A1

Автор: Hiroshi Ohga, Shigeru Yano, Tatsuya Fukugaki, Tetsuya Isobe

Принадлежит: Hitachi High Technologies Corp

After being dispensed, a sample that needs to be quickly measured passes through another unit and is transported to an automatic analyzer. A plurality of units are provided for functions of processing including a dispensing unit that dispenses the sample stored in a sample vessel into another sample vessel. At least one discharge line discharges the sample from the dispensing unit to a transport line and a line that is perpendicular to the discharge line. A reverse direction transport line transports the sample in a direction reverse to a direction in which the sample loaded in the system is transported to the dispensing unit. The sample that is processed by the dispensing unit is transported to a storage unit located on the upstream side of the system, through the reverse direction transport line.

Подробнее

Номер записи: 24

19-07-2012 дата публикации

Automatic analyzer

Номер: US20120183438A1

Автор: Hitoshi Otake, Masaaki Hanawa, Masaharu Nishida, Masaki Shiba

Принадлежит: Hitachi High Technologies Corp

The automatic analyzer includes: a first reagent container storage section storing a plurality of reagent containers; a regent dispensing mechanism for dispensing a reagent from a reagent container stored in the first reagent container storage section; a second reagent container storage section storing a plurality of reagent containers; a reagent container transfer mechanism for transferring a reagent container selected from among reagent containers stored in the second reagent container storage section to the first reagent container storage section; and a controller configured to control the reagent container transfer mechanism to transfer a reagent container from the second reagent container storage section to the first reagent container storage section on the basis of a predetermined priority condition. The predetermined priority condition is one of a reagent provided with an effective calibration curve result, a number of remaining tests, and an expiration date of a reagent.

Подробнее

Номер записи: 25

02-08-2012 дата публикации

Expert-system-based rheology

Номер: US20120192625A1

Автор: James Francis Thomas, Johanne Elizabeth Langridge, John Paul Wilkinson, Samiul Amin, Stephen John Ritchings

Принадлежит: Malvern Instruments Ltd

A rheometer is disclosed that includes rheometry logic that is responsive to a material selection control, to an objective selection control, to material property storage, and to process parameter storage, and is operative to assist the user with a measurement using the rheometer. In another general aspect, a rheometer includes sample history storage operative to store a history that spans a plurality of different operations performed by the rheometer on a same sample.

Подробнее

Номер записи: 26

02-08-2012 дата публикации

Apparatus and method for separating and isolating components of a biological fluid

Номер: US20120193274A1

Автор: Brian K. Cinquini, John R. Chapman, Phillip D. Kingsley, Vijay Kumar

Принадлежит: Individual

A device for separating and isolating components of a biological fluid comprising a container for containing the fluid to be processed, a tube cap assembly for closing the container while providing filling and extraction communication therewith, a float assembly disposed within the container for funneling and controlling biological fluid flow into an inverted domed shaped isolation chamber within the float and controlling the biological fluid flow out of the isolation chamber for effecting an encapsulation or a sealed isolation of at least one component or fraction of the biological fluid flow within the isolation chamber during a centrifugation process. The device further comprising a flexible tube for connecting an extraction passageway disposed within the float assembly and an extraction valve of the tube cap assembly for allowing extraction of at least the one component or fraction encapsulated or isolated within the chamber.

Подробнее

Номер записи: 27

02-08-2012 дата публикации

Slide Processing Apparatus and Method

Номер: US20120195497A1

Автор: Alan Prile, Ian Kerrod, John Temple, Roger Smith, Stephen Hankey

Принадлежит: Thermo Shandon Ltd

A basket processing apparatus that includes a basket storage portion in a form of a horizontal load rail. A plurality of slide storage baskets can be located in series on the rail. Each basket is ‘side loading’ and the side loading aperture of each basket can be selectively covered by a slide retaining bar. When the baskets are placed on the load rail, the basket can be moved along the horizontal rail by a basket moving means. The arrangement of the rail and the basket moving means is such that the baskets can be pushed together and move as a ‘train’. Baskets moved to the pick-up end of the rail can then be removed from the rail and processed. A vertical lift mechanism can be used to remove the basket and transport it to a processing device, for example a coverslipper.

Подробнее

Номер записи: 28

02-08-2012 дата публикации

Devices and method for enrichment and alteration of cells and other particles

Номер: US20120196273A1

Автор: Bruce L. Carvalho, Lotien Richard Huang, Mehmet Toner, Paul Vernucci, Ravi Kapur, Thomas A. Barber, Zihua Wang

Принадлежит: Individual

The invention features devices and methods for the deterministic separation of particles. Exemplary methods include the enrichment of a sample in a desired particle or the alteration of a desired particle in the device. The devices and methods are advantageously employed to enrich for rare cells, e.g., fetal cells, present in a sample, e.g., maternal blood and rare cell components, e.g., fetal cell nuclei. The invention further provides a method for preferentially lysing cells of interest in a sample, e.g., to extract clinical information from a cellular component, e.g., a nucleus, of the cells of interest. In general, the method employs differential lysis between the cells of interest and other cells (e.g., other nucleated cells) in the sample.

Подробнее

Номер записи: 29

16-08-2012 дата публикации

Control of operation conditions within fluidic systems

Номер: US20120204964A1

Автор: Donald J. Morrissey, JR., J. Wallace Parce, Yung-Mae M. Yao

Принадлежит: Caliper Life Sciences Inc

The invention provides methods of controlling environmental conditions within a fluidic system, where such environmental conditions can affect the operation of the system in its desired function, and fluidic channels, devices, and systems that are used in practicing these methods. Such methods are generally directed to environmental control fluids, the movement of such fluids through these systems, and the interaction of these fluids with other components of the system, e.g., other fluids or solid components of the system.

Подробнее

Номер записи: 30

06-09-2012 дата публикации

Apparatus and method for separation of liquid phases of different density and for fluorous phase organic syntheses

Номер: US20120223025A1

Автор: Michal Lebl

Принадлежит: Illumina Inc

A simple, efficient apparatus and method for separating layers of immiscible or partially miscible liquids useful in methods of high-throughput combinatorial organic synthesis or parallel extraction of large libraries or megaarrays of organic compounds is disclosed. The apparatus and method are useful, whether as part of an automated, robotic or manual system for combinatorial organic synthesis or purification (extraction). In a preferred embodiment, an apparatus and method for separating layers of immiscible or partially miscible liquids compatible with microtiter plate type array(s) of reaction vessels is disclosed. Another application of centrifugation based liquid removal was found for washing the plates in biological assays or synthesis on modified substrates.

Подробнее

Номер записи: 31

06-09-2012 дата публикации

Stack of test strips and method for the production thereof

Номер: US20120224996A1

Автор: Herbert Harttig

Принадлежит: Roche Diagnostics Operations Inc

A stack of test strips comprises individual test strips which are stacked over each other and carry a test field for examining a bodily fluid sample. Test strips lying one on top of the other are detachably adhesively bonded to each other so that the test strips can be individually removed from the stack, wherein the test fields are packed in chambers and adjacent test strips form the bottom and the lid of such a chamber. A method for producing such a stack of test strips is also disclosed.

Подробнее

Номер записи: 32

13-09-2012 дата публикации

Temperature control system

Номер: US20120230888A1

Автор: Hisashi Hagiwara, Minoru Asogawa, Tohru Hiramatsu

Принадлежит: Aida Engineering Ltd, NEC Corp

For heating or cooling a sample contained in a vessel portion through a heat transfer member held in contact with the vessel portion, there is used the vessel portion, which has a part formed of an elastic member, expands and contracts for injection and discharge of the sample, is closed other than a connecting port with a channel connected to the vessel, and expands and contracts for injection and discharge of the sample. The vessel portion expands correspondingly to the injection when the sample is injected through an inflow path serving as the channel into the vessel portion contracting in a non-contacting state with the heat transfer member. A predetermined amount of sample is injected into the vessel portion so as to expand the vessel portion, and the vessel portion comes into contact with the heat transfer member. The vessel portion is heated or cooled through the heat transfer member.

Подробнее

Номер записи: 33

20-09-2012 дата публикации

Automatic analyzing device

Номер: US20120239676A1

Автор: Koji Kamoshida, Yasuo Kaneko

Принадлежит: Hitachi High Technologies Corp

In order to improve work efficiency, to exclude human mistakes, and to improve analysis efficiency, an automatic analyzing device that analyzes blood and urine includes a bar code reader and an RFID reader that reads identification information relating to the samples and reagents and that is installed in an operating unit for managing analyzing units in an integrated manner. Test information is stored in a test information storage means of the operating unit and when the identification information stuck on containers of the samples or the reagents is read, the test information is searched. The test information is displayed on a screen of the operating unit as search results; and a function of switching from the search results displayed on the screen to a detailed screen that displays details of the test information when a user selects target test information is provided.

Подробнее

Номер записи: 34

11-10-2012 дата публикации

Rack for sample tubes and reagent holders

Номер: US20120258463A1

Автор: Jeff Williams, Kalyan Handique, Kerry Wilson, Patrick Duffy

Принадлежит: HandyLab Inc

A rack for holding samples and various reagents, wherein the rack may be used for loading the samples and reagents prior to using the reagents. The rack accepts complementary reagent holders, each of which contain a set of reagents for carrying out a predetermined processing operation, such as preparing biological samples for amplifying and detecting polynucleotides extracted from the samples.

Подробнее

Номер записи: 35

25-10-2012 дата публикации

Sample conveying system

Номер: US20120266698A1

Автор: Hiroshi Ohga, Masaaki Hanawa, Tatsuya Fukugaki, Tetsuya Isobe

Принадлежит: Hitachi High Technologies Corp

Conventional conveying lines have required building according to the particular shapes of test tube racks and test tube holders. For this reason, at least two types of dedicated lines, one for test tube racks and one for test tube holders, have been needed in one system, so there has been a tendency for systems to be complex in structure and disadvantageous in cost. To solve these problems, this invention provides a sample conveying system designed so that test tube racks and test tube holders can move on the same line, and high in both cost-effectiveness and reliability.

Подробнее

Номер записи: 36

08-11-2012 дата публикации

Automated analyzer for clinical laboratory

Номер: US20120282684A1

Автор: Gregory E. Gardner, Patrick P. Fritchie, Richard W. Mahoney

Принадлежит: ABBOTT LABORATORIES

A laboratory automation system that is capable of carrying out clinical chemistry assays, immunoassays, amplification of nucleic acid assays, and any combination of the foregoing, said laboratory automation system employing at least one of micro-well plates and deep multi-well plates as reaction vessels. The use of micro-well plates as reaction vessels enables the laboratory automation system to assume a variety of arrangements, i.e., the laboratory automation system can comprise a variety of functional modules that can be arranged in various ways. In order to effectively carry out immunoassays by means of micro-well plates, a technique known as inverse magnetic particle processing can be used to transfer the product(s) of immunoassays from one micro-well of a micro-well plate to another.

Подробнее

Номер записи: 37

15-11-2012 дата публикации

System for handling slides having a linear transport mechanism for transporting the racks

Номер: US20120290127A1

Автор: Bernhard NEEF, Karl-Heinz Westerhoff, Simon Keimer

Принадлежит: LEICA BIOSYSTEMS NUSSLOCH GMBH

The present invention relates to a system ( 10, 100 ) for handling slides, including an input compartment ( 14 ) for inputting racks ( 16 ) and the slides held therein, and a coverslipper module ( 30, 32 ) for coverslipping slides. The system ( 10, 100 ) further includes an output compartment ( 22 ) for outputting racks ( 16 ), a transport unit ( 20 ) for transporting the racks ( 16 ), and a control unit ( 52 ) for controlling the transport unit ( 20 ). The transport unit ( 20 ) is designed to be capable of transporting the racks ( 16 ) between the input compartment ( 14 ), the coverslipper module ( 30, 32 ) and the output compartment ( 22 ).

Подробнее

Номер записи: 38

22-11-2012 дата публикации

Instrument And Method For The Automated Thermal Treatment Of Liquid Samples

Номер: US20120295249A1

Автор: Claudio Cherubini, Emad Sarofim, Kurt Schildknecht, Roger Iten

Принадлежит: Roche Diagnostics Operations Inc

An instrument and a method for the automated thermal treatment of liquid samples are disclosed. An inter-distance between a temperature-controlled receptacle for loading with a plurality of vessels for containing the samples and end portions of optical fibers can be varied, wherein the receptacle is configured to form a thermal communication with the loaded vessels and wherein the optical fibers have first and second end portions. The first end portion and the second end portion of each optical fiber is fixed with respect to each other for transmitting light, wherein the variation of the inter-distance allows the vessels to be loaded to or unloaded from the receptacle and to enable detection of light from the samples contained in the one or more receptacle-loaded vessels.

Подробнее

Номер записи: 39

06-12-2012 дата публикации

System, apparatus, and method for closed tube sampling and open tube sampling for automated clinical analyzers

Номер: US20120308435A1

Автор: Patrick P. Fritchie

Принадлежит: ABBOTT LABORATORIES

A centrifuge to which sample tubes can be introduced while the centrifuge is in motion. The centrifuge comprises a carousel having an upper portion and a lower portion. The upper portion of the carousel has a plurality of positions for sample tubes for a centrifugation operation, a plurality of drive mechanisms attached to the upper portion of the carousel, a movable element mounted upon each drive mechanism, the movable element capable of traversing the length of the drive mechanism when the drive mechanism is actuated, a sample tube-holding assembly comprising a sample tube holder and a bearing attached to each movable element, and at least one balancing element capable of contributing to a force vector that cancels an imbalance vector generated by rotation of the centrifuge.

Подробнее

Номер записи: 40

06-12-2012 дата публикации

Biosample plate with data storage and wireless communication means

Номер: US20120309111A1

Автор: Anna Wanda Topol, Daniel James Winarski, Nils Haustein, Thorsten Krause

Принадлежит: International Business Machines Corp

Embodiments of the disclosure relate to a biosample plate that includes a memory component for storing information related to the biosample, biosample plate and biosample analysis data, and a wireless communication interface for transferring information to and from the biosample plate. The biosample plate may be used with an analyzing and data recording system such as an electromagnetic tape drive. The disclosed biosample plate facilitates the correlation between a large number of biosample plates and data as data remains with the corresponding biosamples both when the biosample plates are in use and when they are in storage. The wireless communication interface may comprise an antenna disposed in a biosample plate for data transmission to and from the biosample plate by radio signals.

Подробнее

Номер записи: 41

13-12-2012 дата публикации

Imaging system and techniques

Номер: US20120312957A1

Автор: Bikash Sabata, Chris Todd, Glenn Stark, Gregory L. LONEY

Принадлежит: BioImagene Inc, Ventana Medical Systems Inc

Systems and techniques for an optical scanning microscope and/or other appropriate imaging system includes components for scanning and collecting focused images of a tissue sample and/or other object disposed on a slide. The focusing system described herein provides for determining best focus for each snapshot as a snapshot is captured, which may be referred to as “on-the-fly focusing.” The devices and techniques provided herein lead to significant reductions in the time required for forming a digital image of an area in a pathology slide and provide for the creation of high quality digital images of a specimen at high throughput.

Подробнее

Номер записи: 42

20-12-2012 дата публикации

Analysis device and reagent container

Номер: US20120321513A1

Автор: Nobuhiro Kitagawa, Takaaki Nagai, Yuichi Hamada

Принадлежит: Sysmex Corp

An analysis device for particle analysis, configured in such a manner that a reagent container is set in the device by inserting the reagent container from a side surface of the device toward the inside thereof, the reagent container having, near the forward end thereof, a suction pipe entrance portion into which a suction pipe can enter. The analysis device is provided with: a reagent container holding portion which holds the reagent container inserted from the suction pipe entrance portion side; and the suction pipe which enters, from above, the suction pipe entrance portion of the reagent container held by the reagent container holding portion and which sucks a reagent within the reagent container. The reagent container holding portion includes a guide member for guiding the insertion of the reagent container, which is inserted from the suction pipe entrance portion side, into the reagent container holding portion.

Подробнее

Номер записи: 43

27-12-2012 дата публикации

Method of Pre-Treatment and Staining of a Biological Sample and Device for Support of a Biological Sample and Methods of Using Such Device

Номер: US20120330564A1

Автор: David A. Stanforth, Lars Winther, Loren L. Bland, Marc E. Key, Martin N. Lindberg

Принадлежит: DakoCytomation Denmark AS

There is disclosed a method of pre-treatment and staining, according to a protocol, of a biological sample disposed upon the surface of a carrier, the method comprising the step of recording at least one parameter relating to at least one protocol step in a non-volatile memory located either upon or within the carrier or a device incorporating the carrier. Also disclosed is a device comprising: a non-volatile memory; a surface of the device adapted to carry a biological sample; and communications means electrically coupled to the memory for enabling data transmission to or from an external apparatus. Also disclosed is a method of controlling processing of a biological sample disposed upon a carrier, comprising: providing, upon or within the carrier or an apparatus holding the carrier, a non-volatile memory having information relating to sample processing priority or protocol; reading the information; and scheduling the processing based upon the information.

Подробнее

Номер записи: 44

03-01-2013 дата публикации

Systems and methods for sample display and review

Номер: US20130002847A1

Автор: Adam Yie, David Zahniser, Michael Zahniser

Принадлежит: Constitution Medical Inc

Methods and systems for displaying images of cells in a sample include obtaining a plurality of images of cells in the sample, where each image corresponds to one of the cells in the sample, determining values of at least one property for each of the cells based on the plurality of images, arranging the plurality of images to form a first image array, where the images are ordered in the first image array based on the values of the at least one property, displaying the first image array, sorting the plurality of images to form a second image array in which an ordering of the images is different from the first image array, and displaying the second image array, where the sample includes blood and the cells include red blood cells.

Подробнее

Номер записи: 45

03-01-2013 дата публикации

Apparatus and method for processing biological material

Номер: US20130005032A1

Автор: James C. Laird, Kyungyoon Min, Thomas E. Dudar

Принадлежит: Baxter International Inc

The application discloses an apparatus and method for processing biological material, including a suspension of cells.

Подробнее

Номер записи: 46

10-01-2013 дата публикации

Modular sample store

Номер: US20130011226A1

Автор: Beat Reuteler, Christian Cachelin, Johann Camenisch, Jürg Tanner, Mirko Hebenstreit

Принадлежит: Brooks Automation Inc

A modular sample storeincluding a storage area; a service area; a transfer area; a motorized robot with a lifting device and at least one platform; and a controller. The sample store service area includes one integrally formed cubic vat module and the sample store storage area includes at least one integrally formed cubic vat module. Each one of the aforementioned vat modules includes an essentially horizontal vat floor and four joining vat walls that are connected to the vat floor and that are leaving an open vat space. The modular sample store also includes upper side walls and a cover plate to close the sample store. Each vat floor and vat wall includes an outside liner and an inside liner, which outside and inside liners in each case are separated by a clearance. This clearance is essentially filled with a polymer foam material that provides fixation of the outside and inside liners to each other as well as thermal insulation of and reinforcement to the thus integrally formed cubic vat module sandwich construction.

Подробнее

Номер записи: 47

07-02-2013 дата публикации

Biological sample-processing apparatus having a door with space for receiving reagent tanks

Номер: US20130034476A1

Автор: David Daf

Принадлежит: Taigen Bioscience Corp

A biological sample-processing apparatus has a sample-processing chamber, which has a door with space for receiving reagent tanks. The reagent supply tanks have conduits in fluid communication with reagent buffer tanks in the sample-processing chamber. The door has a pivot with a hollow interior. At least one conduit connects the reagent supply tanks to the reagent buffer tanks through the hollow interior of the pivot. The present invention provides a modification of the door of a biological sample-processing apparatus so that the door is equipped with reagent supply tanks that contain reagents for processing biological samples and that facilitate the operation of the processing and increase convenience, and further, enable more of the apparatuses to be allocated in the same space.

Подробнее

Номер записи: 48

07-02-2013 дата публикации

System and Method for the Continuous Extraction of a Liquid Phase of Microsamples, and Automated Installation for Taking Them, For Carrying Out the Extraction and Taking Measurements

Номер: US20130035223A1

Автор: Jean-Marc Reymond, Philippe Mangeot, Sophie Kerhoas-Cavata

Принадлежит: Commissariat a lEnergie Atomique et aux Energies Alternatives CEA

A continuous automated extraction system and method for physically extracting at least one liquid phase of a series of liquid microsamples which are taken beforehand in discrete packets, both in space and in time, and are in stored is provided. The method may include an extraction system having a centrifuge provided with a plurality of microholders, at least one of which is filled with the corresponding microsample and includes a filling upper portion that is extended by a separating lower portion of smaller cross section than that of the upper portion. Each filled microholder has a mass which is more than ten times the mass of this microsample, in such a way that it is possible to extract, by centrifugation, at a given instant, only a single microsample contained in a single microholder, or several microsamples contained in some or all of these microholders, progressively as the latter are filled.

Подробнее

Номер записи: 49

14-02-2013 дата публикации

Apparatus for and method of processing biological samples

Номер: US20130040376A1

Автор: Alexander Khorlin, Daniel Bezdek, Espir Kahatt, Joseph Amshey, Kornelija Zgonc, Lance Parsons, Michael Tacher, Timothy Powers, Timothy Updyke, Todd Peterson

Принадлежит: Life Technologies Corp

The present invention provides systems, devices, apparatuses and methods for automated bioprocessing. Examples of protocols and bioprocessing procedures suitable for the present invention include but are not limited to: immunoprecipitation, chromatin immunoprecipitation, recombinant protein isolation, nucleic acid separation and isolation, protein labeling, separation and isolation, cell separation and isolation, food safety analysis and automatic bead based separation. In some embodiments, the invention provides automated systems, automated devices, automated cartridges and automated methods of western blot processing. Other embodiments include automated systems, automated devices, automated cartridges and automated methods for separation, preparation and purification of nucleic acids, such as DNA or RNA or fragments thereof, including plasmid DNA, genomic DNA, bacterial DNA, viral DNA and any other DNA, and for automated systems, automated devices, automated cartridges and automated methods for processing, separation and purification of proteins, peptides and the like.

Подробнее

Номер записи: 50

21-03-2013 дата публикации

Microfluidic device

Номер: US20130071304A1

Автор: Byung Hee Jeon

Принадлежит: Cytogen Inc

A micro-fluidic device includes a filter cabinet, a first filtering unit and a second filtering unit. The filter cabinet includes a first path and a second path branched from the first path. The first path and the second path are formed within the filter cabinet so that a sample containing different kinds of targets can flow through the first path and the second path. The first filtering unit is installed in an upstream portion of the first path to filter the different kinds of targets from the sample, the first filtering unit configured to guide the different kinds of targets toward the second path. The second filtering unit is installed in the second path to receive the different kinds of targets from the first filtering unit and to filter the different kinds of targets on a size-by-size basis.

Подробнее

Номер записи: 51

28-03-2013 дата публикации

Method And Devices For The Cross-Referencing Of Identification Of Tissue Slice Supports For Microtomised Analytical Samples

Номер: US20130078669A1

Автор: Hans L. Heid, Jose Novoa

Принадлежит: MICROM INTERNATIONAL GMBH

The invention relates to a method and device for the cross-referencing of identification ( 1 ) of tissue slice supports ( 2 ), for microtomised analytical samples still to be mounted thereon, with identification information ( 3 ) of a tissue sample holder ( 4 ) of a tissue sample ( 5 ) which is not yet microtomised. The conventional problem of cross-referencing is improved in a simple manner, whereby the identification information ( 3 ) for the tissue sample holder ( 4 ) is automatically detected when positioned in the microtome ( 6 ) and an identification ( 1 ) corresponding thereto is automatically transferred to at least one tissue slice support ( 2 ) and that tissue slice support ( 2 ), provided with the identification ( 1 ), is dispensed for application of the tissue sample slice at the moment when a tissue sample slice must be applied to a tissue slice support ( 2 ).

Подробнее

Номер записи: 52

28-03-2013 дата публикации

Systems and methods for multi-analysis

Номер: US20130079236A1

Автор: Elizabeth Holmes

Принадлежит: Theranos Inc

Systems and methods are provided for sample processing. A device may be provided, capable of receiving the sample, and performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing multiple assays. The device may comprise one or more modules that may be capable of performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing the steps using a small volume of sample.

Подробнее

Номер записи: 53

04-04-2013 дата публикации

System and Method for Monitoring Time Intervals During Blood Parameter Monitoring

Номер: US20130085471A1

Автор: Hans-Otto Maier, Horst Schmoll, Matthias Paetzold, Torsten Doenhoff

Принадлежит: B Braun Melsungen AG

A system and method for monitoring at least one blood parameter of the blood of different patients, comprising a plurality of access devices for establishing at least one means of access to the blood of each patient through the skin, a plurality of removal devices for removing a quantity of blood from each patient in order to obtain at least one blood sample, at least one blood analysis device for analysing the blood sample with respect to predeterminable blood parameters and for generating individual blood parameter data sets, a calculation device which can be used jointly for a plurality of blood parameter data sets of different patients for calculating data sets of drug parameters of the drugs to be administered to the respective patient on the basis of the individual blood parameter data sets, and a plurality of supply devices for supplying the respective drug having the calculated drug parameters.

Подробнее

Номер записи: 54

11-04-2013 дата публикации

Fluid controlling apparatus and method of controlling fluid by using the same

Номер: US20130086998A1

Автор: Hyo-Young Jeong, Jeong-Gun Lee, June-Young LEE, Sang-Hyun Baek, Tae-Seok Sim

Принадлежит: SAMSUNG ELECTRONICS CO LTD

A fluid controlling apparatus including at least one sample chamber for holding a fluid containing target materials; a cleaning chamber for holding a cleaning solution; a first multi-port connected to the at least one sample chamber through a first channel and connected to the cleaning chamber through a second channel; a filter portion, connected to the first multi-port through a third channel, for filtering the target materials; and a first pump, connected to the filter portion, for applying a pressure; and a method of controlling a fluid using the fluid controlling apparatus, which comprises passing the fluid containing the target materials from the at least one sample chamber to the filter portion; and cleaning a path of the fluid by passing the cleaning solution through the path.

Подробнее

Номер записи: 55

23-05-2013 дата публикации

Aliquotter system and workflow

Номер: US20130125675A1

Автор: Charles W. JOHNS, Martin Müller

Принадлежит: Beckman Coulter Inc

A method is disclosed. The method includes aspirating an aliquot volume of a sample in a primary sample container located in an aspiration position in an aliquotter module, and dispensing the aliquot volume of the sample in a secondary sample container located in a dispensing position in the aliquotter module. The method also includes the step of causing the secondary sample container to leave the aliquotter module before the primary sample container.

Подробнее

Номер записи: 56

23-05-2013 дата публикации

Body fluid testing device

Номер: US20130131480A1

Автор: Hugo Schrem, Volker Zimmer, Werner Ruhl

Принадлежит: Roche Diagnostics Operations Inc

Body fluid testing device for analyzing a body fluid comprises a test media tape adapted to collect the body fluid. The test media tape comprises a tape and test media portions. A free tape portion without test medium is located between successive test media portions. The testing device further comprises a supply portion. The supply portion comprises a housing in which uncontaminated test media tape is contained. The housing further has an opening for withdrawing test media tape from the housing. The testing device further has a sealing means for closing the opening against the surrounding. A free tape portion of the test media tape is located between a wall of the housing and the sealing means when the sealing means closes the opening. Further aspects concern a test media cassette with sealing means and a method for providing test media while holding them sealed against humidity during onboard storage.

Подробнее

Номер записи: 57

23-05-2013 дата публикации

Chromatography configuration interface

Номер: US20130132897A1

Автор: Christof Schultz, Dominic Casenas, Farah Mavandadi

Принадлежит: Bio Rad Laboratories Inc

Systems and methods that facilitate the setup and visualization of a configurable process, for example a chromatography experiment to be conducted using a configurable chromatography system. A user interface displays category regions representing sections of a process, and displays a plurality of selectable items representing components appropriate for placement in the category regions. A user interface control causes selection of one of the selectable items and placement of the selected item into one of the category regions, to define a selected process configuration. The user interface control may be a scrolling control that causes a set of selectable items appropriate for placement in the respective category region to scroll through the category region. When the computer displaying the user interface is also connected to the system being configured, the user interface may also facilitate setup, monitoring, and control of the resulting process.

Подробнее

Номер записи: 58

30-05-2013 дата публикации

System and method including analytical units

Номер: US20130137110A1

Автор: Charles S. Kraihanzel

Принадлежит: Beckman Coulter Inc

Systems and methods for processing and analyzing samples are disclosed. The system may process samples, such as biological fluids, using assay cartridges which can be processed at different processing locations. In some cases, the system can be used for PCR processing. The different processing locations may include a preparation location where samples can be prepared and an analysis location where samples can be analyzed. To assist with the preparation of samples, the system may also include a number of processing stations which may include processing lanes. During the analysis of samples, in some cases, thermal cycler modules and an appropriate optical detection system can be used to detect the presence or absence of certain nucleic acid sequences in the samples. The system can be used to accurately and rapidly process samples.

Подробнее

Номер записи: 59

20-06-2013 дата публикации

Gas Chromatograph Column Markings to Determine Length

Номер: US20130152666A1

Автор: Scott T. Quarmby

Принадлежит: Thermo Finnigan LLC

A gas chromatograph column is marked with a code that allows an operator or machine to accurately determine the distance between two points on the column by comparing markings at the two points on the column. The code may be human or machine readable.

Подробнее

Номер записи: 60

20-06-2013 дата публикации

Method for producing an analytical consumable

Номер: US20130153152A1

Автор: Joerg Dreibholz, Wolfgang Schwoebel

Принадлежит: Roche Diagnostics Operations Inc

A method for producing an analytical consumable is proposed. The analytical consumable comprises at least one carrier and at least one analytical aid connected to the carrier. At least one optically sensitive material is applied to the carrier, said material being designed to carry out at least one optically detectable alteration in the event of action of an electromagnetic radiation. In at least one coding step, at least one function information item about the analytical consumable is introduced into the optically sensitive material by means of electromagnetic radiation. The function information item is designed to enable at least one analytical instrument to use the analytical consumable correctly.

Подробнее

Номер записи: 61

20-06-2013 дата публикации

Disease simulation system and method

Номер: US20130157238A1

Автор: Stephen J. Brown

Принадлежит: Robert Bosch Healthcare Systems Inc

A method of diabetes management including receiving a plurality of readings over time from an analyte sensor, processing each of the readings to generate analyte data, receiving information about external factors, using the analyte data to estimate an amount of medication to be dispensed from a single dose medication device based on the analyte data in combination with the external factors, and displaying an instruction to deliver the amount of medication.

Подробнее

Номер записи: 62

20-06-2013 дата публикации

Waste ramp for reagent cards

Номер: US20130157372A1

Автор: Aaron Sung-Lien Tang, Kenneth Galano, Michael Parker

Принадлежит: Siemens Healthcare Diagnostics Inc

An automated analyzer for reagent cards having a leading end, a trailing end and a length between the leading end and the trailing end comprises a travel surface assembly having a card travel surface and an edge. A test analyzing mechanism is adjacent to the travel surface, and a waste receptacle is adjacent to the edge below the travel surface. The waste receptacle has a side and a waste cavity. A ramp member positioned below the travel surface has an end and a sloped surface, and is movable between an extended position where the sloped surface extends into the waste cavity, and a retracted position where the end is spaced from the side a distance greater than the length of the reagent card. A moving mechanism operably coupled with the ramp member is configured to move the ramp member between the extended position and the retracted position.

Подробнее

Номер записи: 63

27-06-2013 дата публикации

Reader Devices for Optical and Electrochemical Test Devices

Номер: US20130162981A1

Автор: Graham Davis, PIERRE Emeric, Sergey Gershtein, Thomas Ewart

Принадлежит: ABBOTT POINT OF CARE INC

This invention relates generally to devices and methods for performing optical and electrochemical assays and, more particularly, to devices having optical and electrochemical detectors and to methods of performing optical and electrochemical assays using such devices. The present invention is particularly useful for performing immunoassays and/or electrochemical assays at the point-of-care.

Подробнее

Номер записи: 64

27-06-2013 дата публикации

Particle monitoring with secure data logging

Номер: US20130166251A1

Автор: Eric Robert Wright, Paul H. Yates, Robert A. Latimer, Walter D. MODIC

Принадлежит: Hach Co

A data logging monitoring instrument and related methods are described. One aspect provides a particle counting instrument, including: one or more sensors; a storage system; and a processing system coupled to the storage system, the processing system being configured to accumulate measurement data ascertained via the one or more sensors in the storage system into one or more log files; wherein the one or more log files are stored in a secure file format that is compatible with other non-particle counting instrument information processing device applications. Other embodiments are described.

Подробнее

Номер записи: 65

18-07-2013 дата публикации

Microfluidic devices

Номер: US20130183659A1

Автор: Darren R. Link, David Marran, Jonathan M. Rothberg, Michael Weiner

Принадлежит: Raindance Technologies Inc

The present invention provides novel microfluidic substrates and methods that are useful for performing biological, chemical and diagnostic assays. The substrates can include a plurality of electrically addressable, channel bearing fluidic modules integrally arranged such that a continuous channel is provided for flow of immiscible fluids.

Подробнее

Номер записи: 66

18-07-2013 дата публикации

Cell processing apparatus, sample preparation apparatus, and cell analyzer

Номер: US20130183747A1

Автор: Hironori Kobayashi, Junyi Ding, Koki Tajima, Masakazu Fukuda, Ryuichiro Ebi

Принадлежит: Sysmex Corp

A cell processing apparatus includes a storage container that contains liquid L including a biological sample; a filter that prevents a first cell C 1 in the biological sample from passing and allows a second cell C 2 having a smaller diameter than that of the first cell C 1 to pass; and a filtration cylinder for separating, in the storage container and via the filter, the liquid L into a first liquid L 1 mainly including the first cell C 1 and a second liquid L 2 mainly including the second cell C 2 . A measurement target cell filtered by the filter among other cells can be easily collected.

Подробнее

Номер записи: 67

18-07-2013 дата публикации

Apparatus, method and article to perform assays using assay strips

Номер: US20130183772A1

Автор: James E. Fleming, Jesse M. McGrew, Johnny Humphreys, Patrick Nicholes, Stephen P. McGrew

Принадлежит: GenPrime Inc

An assay system includes an optical imager to acquire high resolution images of assay strips (e.g., lateral flow immunochromatographic test strips) and performs image processing to identify individual assay strips and determine results for each assay strip, by quantifies the presence or absence of test signal line(s) and control signal line(s). Assay strips may be in a holder or carrier contained in a specimen container also holding a specimen. The assay system automatically logs all results and data to a database that stores a high resolution image of the original immunochromatographic assay, the values of test line(s) and control line(s), and the test result. A user interface directs an end user through operation.

Подробнее

Номер записи: 68

18-07-2013 дата публикации

Integrated Test Device for Optical Detection of Microarrays

Номер: US20130184188A1

Автор: Graham Davis, Katrina Di Tullio, PIERRE Emeric, Sergey Gershtein, Smitha Sutrala, Thomas Ewart

Принадлежит: ABBOTT POINT OF CARE INC

This invention relates generally to devices and methods for performing optical and electrochemical assays and, more particularly, to testing devices having an optically readable microspot array and/or an electrochemical detector and to methods of performing microspot arrays and electrochemical assays using such devices. The present invention is particularly useful for performing immunoassays and/or electrochemical assays at the point-of-care.

Подробнее

Номер записи: 69

08-08-2013 дата публикации

Automatic slide loading device for micro array scanner and its methods of use

Номер: US20130203611A1

Автор: Danyang Mei, Dong Wang, Gang Li, Hang Li, Huihui Teng, Jing Cheng, Wenjun Wang, Xiaokun Qin, Zhengde Feng

Принадлежит: CapitalBio Corp, TSINGHUA UNIVERSITY

An automatic slide loading device for microarray scanner comprises slide holders ( 1 ), a carrier device ( 2 ) and a positioning chamber ( 3 ), wherein the slide holder ( 1 ) can hold microarray slides ( 6 ) and the slide holder ( 1 ) is placed out of the scanning platform of the microarray scanner when the microarray scanner is in off work state, wherein the carrier device ( 2 ) is connected to the positioning chamber ( 3 ) and the carrier device ( 2 ) can load the slide holder ( 1 ) into the positioning chamber ( 3 ), wherein the positioning chamber ( 3 ) is placed above the scanning platform of the microarray scanner and is used to precisely locate the working surface of the microarray slides ( 6 ) in the slide holder ( 1 ).

Подробнее

Номер записи: 70

15-08-2013 дата публикации

System and method including analytical units

Номер: US20130209334A1

Автор: Alan N. Johnson, Brian D. Wilson, Daniel R. Schmidt, David L. Anderson, Joshua D. Wiltsie, Matthew D. Erickson, Michael J. Rosen

Принадлежит: Beckman Coulter Inc

Systems and methods for processing and analyzing samples are disclosed. The system may process samples, such as biological fluids, using assay cartridges which can be processed at different processing locations. In some cases, the system can be used for PCR processing. The different processing locations may include a preparation location where samples can be prepared and an analysis location where samples can be analyzed. To assist with the preparation of samples, the system may also include a number of processing stations which may include processing lanes. During the analysis of samples, in some cases, thermal cycler modules and an appropriate optical detection system can be used to detect the presence or absence of certain nucleic acid sequences in the samples. The system can be used to accurately and rapidly process samples.

Подробнее

Номер записи: 71

22-08-2013 дата публикации

Cell analyzer, cell processing apparatus, specimen preparing apparatus

Номер: US20130217110A1

Автор: FuKoki TAJIMA, Ryuichiro Ebi, Toshihiro Ootani

Принадлежит: Sysmex Corp

The present invention provides a cell analyzer which comprises: a cell dispersion unit which causes aggregated cells in a biological specimen to be dispersed, through a shearing force applying process of applying a shearing force to the aggregated cells and an ultrasonic dispersion process of dispersing the aggregated cells, by using ultrasonic waves; a detection unit which detects characteristics information reflecting properties of the cells in the biological specimen on which the shearing force applying process and the ultrasonic dispersion process have been performed; and an analysis unit which analyzes the cells in the biological specimen, based on a detection result from the detection unit.

Подробнее

Номер записи: 72

29-08-2013 дата публикации

Mixing apparatus

Номер: US20130224089A1

Автор: Daisuke Matsumoto, Hitoshi Okai, Junichi Oka, Takashige Tanaka

Принадлежит: Arkray Inc

A mixing apparatus includes: a mixing container with a discharge port for discharging mixed liquid; a filter paper covering the discharge port to temporarily retain the liquid; a receiving unit with a waste liquid collecting portion for receiving a first liquid discharged from the discharge port through the filter paper, and a measuring portion for receiving a second liquid subjected to treatment different from treatment for the first liquid; and an operation portion for enabling selection between a first receiving state in which the waste liquid collecting portion receives the first liquid and a second receiving state in which the measuring portion receives the second liquid, and also for controlling the movement of the first liquid or the second liquid.

Подробнее

Номер записи: 73

29-08-2013 дата публикации

System and method for delta checking of biological samples

Номер: US20130226605A1

Автор: James J. Miller, Thomas Kampfrath

Принадлежит: University of Louisville Research Foundation ULRF

Methods of the invention automatically determine analytes and delta thresholds to use in delta checking patient data. The analytes and thresholds are determine from a populating specific set of patient data. Variance in analytes for multiple patient samples is determined. In additional, variance in intentionally mismatched patient samples is determined. The best analytes to differentiate between patients are determined along with delta thresholds. Preferred embodiments conduct evaluation with a multivariate delta threshold determination for ongoing testing of results from the patient. Preferred software provides an interactive interface that allows a user to set a number of flags that can be handled per a predetermined time period, and automatically adjusts the delta threshold to that number of flags.

Подробнее

Номер записи: 74

26-09-2013 дата публикации

Sample packing device

Номер: US20130251603A1

Автор: Hisashi Hagiwara, Minoru Asogawa, Tohru Hiramatsu

Принадлежит: NEC Corp

Provided is a sample packing device for packing a sample with respect to a microchip for performing reaction of a micro component contained in the sample, the microchip at least including: a sample reservoir; a reaction reservoir; and a channel connected between the sample reservoir and the reaction reservoir, in which a package including a sample chamber packed in advance with the sample is mounted on the microchip so as to pack the sample in the sample chamber into the sample reservoir.

Подробнее

Номер записи: 75

03-10-2013 дата публикации

Sample processing apparatus, sample analyzer, sample analyzing system, sample processing system and sample processing method

Номер: US20130260412A1

Автор: Hiroo Tatsutani

Принадлежит: Sysmex Corp

The present invention is a sample processing apparatus. The sample processing apparatus includes: a reader configured to read, from a storage medium attached to a sample container containing a sample or a sample rack supporting the sample container, an analysis value which has been generated by a sample analyzer analyzing the sample for a predetermined analysis item; a sample processing section which comprises an operating mechanism configured to perform an operation for processing the sample, and a controller configured to control the operating mechanism of the sample processing section so as to perform processing on the sample based on the analysis value read by the reader.

Подробнее

Номер записи: 76

03-10-2013 дата публикации

Systems and methods for detecting fallen containers suitable for apparatus for automated evaluation of microorganism growth in test samples

Номер: US20130260448A1

Автор: James Knebel, Mark Wilson, Thierry Vivet

Принадлежит: Biomerieux Inc

Methods, systems, computer program products, apparatus and circuits are configured to detect fallen containers upstream or proximate an intake zone suitable for automated evaluation apparatus using different sensors, including at least one lower sensor and at least one upper sensor which is positioned to project an optical signal at a height corresponding to a top portion of an upright container to thereby allow an increased reliability in detection of different orientations and positions of fallen containers. An optional second lower sensor may be used which is longitudinally spaced apart from the first lower sensor and the lower sensors can transmit optical signals across the container travel path that do not intersect.

Подробнее

Номер записи: 77

17-10-2013 дата публикации

Device for performing a blood, cell, and/or pathogen count and methods for use thereof

Номер: US20130273524A1

Автор: Joel R. L. Ehrenkranz

Принадлежит: Joel R. L. Ehrenkranz

Devices and methods for performing a point of care blood, cell, and/or pathogen count or a similar blood test. Disclosed herein are systems that can be used to provide rapid, accurate, affordable laboratory-quality testing at the point of care. The systems described herein are capable of imaging and counting individual cells in a prepared cell sample (e.g., a peripheral blood smear or a blood sample prepared in a microfluidic device) or another prepared cell-containing sample without the need for a microscope or other expensive and cumbersome optics. The systems described herein are designed to eliminate or replace expensive, centralized clinical testing equipment and technical personnel. Such systems may include automated data reporting and decision support.

Подробнее

Номер записи: 78

24-10-2013 дата публикации

Automatic calibration of a microscope scanning system

Номер: US20130278941A1

Автор: Thomas Loerch

Принадлежит: Metasystems Hard and Software GmbH

The invention provides a method for automatic calibration of slides and a method for automatic calibration of slide frames and a slide for performing the method. To this end, slide frames ( 4; 210 ) with at least one slide seat and slide ( 212 a - 212 h; 300 ) are provided with a calibration marking ( 304 ). In particular the inventive slide ( 212 a - 212 h; 300 ) includes a slide substrate ( 302 ) and a calibration marking ( 304 ), the calibration marking ( 304 ) being connected to the slide substrate ( 302 ).

Подробнее

Номер записи: 79

24-10-2013 дата публикации

Automatic analyzer

Номер: US20130280130A1

Автор: Fridl Lang, Kenji Teshigawara, Osamu Matsumoto, Peter Wolf, Roland Ihrig, Sayaka Sarwar, Shigeki Matsubara, Sylvia Rosenblatt

Принадлежит: Hitachi High Technologies Corp, Roche Diagnostics Operations Inc

Unlike conventional reagent storing means of an analyzing unit having a cold-storage function, replacement reagent storing means having no cold-storage function requires reagent management of a higher order. An automatic analyzer is provided that manages the placing elapsed time for a reagent vessel in replacement reagent storing means 2 , compares the placing elapsed time for the reagent with a permissible placing limit value stored as one of analysis parameters for each analysis item, and determines as to whether or not the placing elapsed time exceeds permissible limit value. In this way, the analyzer prevents the degradation of the reagent and automatically transfers the reagent to an analyzing section for performing measurement.

Подробнее

Номер записи: 80

07-11-2013 дата публикации

Quality Assurance System and Method for Point-of-Care Testing

Номер: US20130292246A1

Автор: Eric Brouwer, Michael P. Zelin, Steven Breeze

Принадлежит: ABBOTT POINT OF CARE INC, iStat Corp

An improved quality assurance system and method for point-of-care testing are disclosed. The present invention provides quality assurance for laboratory quality tests performed by a blood analysis system or the like at the point of patient care without the need for running liquid-based quality control materials on the analysis system. Quality assurance of a quantitative physiological sample test system is performed without using a quality control sample by monitoring the thermal and temporal stress of a component used with the test system. Alert information is generated that indicates that the component has failed quality assurance when the thermal and temporal stress exceeds a predetermined thermal-temporal stress threshold. Alternatively, the present invention provides quality assurance for laboratory quality tests performed by a blood analysis system or the like at the point of patient care by minimizing the need for running liquid-based quality control materials on the analysis system.

Подробнее

Номер записи: 81

14-11-2013 дата публикации

Encapsulated reagents and methods of use

Номер: US20130302803A1

Автор: Lee H. Angros

Принадлежит: Individual

The present invention contemplates use of encapsulated aqueous and non-aqueous reagents, solutions and solvents and their use in laboratory procedures. These encapsulated aqueous or non-aqueous reagents, solutions and solvents can be completely contained or encapsulated in microcapsules or nanocapsules that can be added to an aqueous or non-aqueous carrier solution or liquid required for medical and research laboratory testing of biological or non-biological specimens.

Подробнее

Номер записи: 82

21-11-2013 дата публикации

Device for reading barcodes

Номер: US20130306729A1

Автор: Ekaterina Dilks, Timothy John Dilks

Принадлежит: ZIATH LTD

An image capture device for capturing an image of a test tube rack comprising a plurality of test tubes each having an individual barcode thereon, the image capture device comprising: an enclosure comprising a transparent window which, in use, is adjacent the test tube rack to be imaged; at least one camera mounted within the enclosure to capture an image through the window; a plurality of light sources mounted within the enclosure to illuminate the window and at least one light blocking element arranged to at least partially block light radiating from at least one of the plurality of light sources, wherein the plurality of light sources and the at least one light blocking element are arranged within the enclosure to provide generally uniform illumination across the whole window and to reduce unwanted reflections.

Подробнее

Номер записи: 83

28-11-2013 дата публикации

Test chip and test chip unit incorporated with test chip

Номер: US20130312546A1

Автор: Shigeru Wada

Принадлежит: KONICA MINOLTA INC

The present invention is characterized in being provided with a chip main body, which is provided with a flow channel having the end portion thereof opened in the surface, and a sheet-like sealing member, which brings the inside of the flow channel into a hermetically closed state by covering at least the opening in the surface of the chip main body. The present invention is also characterized in that in the sealing member, a plurality of sheets are laminated, said sheets including a first sheet, which has ductility and elasticity such that the first sheet can be penetrated by means of a nozzle member, and a second sheet having ductility lower than that of the first sheet, the sheets adjacent to each other are bonded with an adhesive agent or a cohesive agent, and that the second sheet is positioned further toward the chip main body side than the first sheet.

Подробнее

Номер записи: 84

05-12-2013 дата публикации

System for performing automated solid phase extractions

Номер: US20130323138A1

Автор: Thomas J. Demmitt

Принадлежит: Biolytic Lab Performance Inc

The invention provides an improved instrument for automation of solid phase extraction chemistries typically used in biotechnology labs. The instrument includes a mechanism for transferring samples dissolved in a liquid from initial containers to reaction columns that are used to perform solid phase extractions. Samples, reaction columns and collection containers are in microtiter plate format or tubes that are on 18 millimeter centers. The transfer system is automatically cleaned after use in preparation for the next use. A dispense manifold is used to dispense various reagents into the reaction columns. Pressure differential is used to move reagents through reaction columns. A sliding cover is used to divert the reagent exiting reaction columns to waste or allowing collection of sample as it exits outlets of reaction columns. Samples are automatically collected in microtiter plates or in individual tubes or vials.

Подробнее

Номер записи: 85

30-01-2014 дата публикации

TEST STRIP ANALYZING APPARATUS HAVING WHEEL EJECTOR

Номер: US20140027466A1

Автор: Bag Jeong In, Choi In Hwan

Принадлежит: PHILOSYS CO., LTD.

Disclosed herein is a test strip analyzing apparatus having a wheel ejector. The test strip analyzing apparatus having a wheel ejector includes a body, a measurement unit, and an ejector. The measurement unit is disposed on one side of the body. The ejector is disposed in the measurement unit, and selectively inserts and discharges a test strip. Furthermore, the ejector includes a wheel that is rotatably mounted in the measurement unit so that a part of the wheel is exposed outside a top portion of the measurement unit and that selectively inserts and discharges the test strip using frictional force. 1. A test strip analyzing apparatus having a wheel ejector , comprising a body , a measurement unit disposed on one side of the body , and an ejector disposed in the measurement unit and configured to selectively insert and discharge a test strip ,wherein the ejector comprises a wheel that is rotatably mounted in the measurement unit so that a part of the wheel is exposed outside a top portion of the measurement unit and that selectively inserts and discharges the test strip using frictional force.2. The test strip analyzing apparatus as set forth in claim 1 , wherein the wheel is made of a silicon claim 1 , rubber or synthetic rubber material that is capable of producing a large amount of frictional force.3. The test strip analyzing apparatus as set forth in claim 1 , wherein a rugged portion is formed on a surface of the wheel so as to prevent slipping.4. The test strip analyzing apparatus as set forth in claim 1 , wherein a cover is provided on a top portion of the measurement unit so as to cover the exposed portion of the wheel. The present invention relates, in general, to a test strip analyzing apparatus having a wheel ejector, and, more particularly, to a test strip analyzing apparatus having a wheel ejector, which can facilitate the insertion and discharging of a test strip and can prevent the apparatus and a user from being contaminated by residual bio-samples. ...

Подробнее

Номер записи: 86

30-01-2014 дата публикации

Conditioning chamber for storing samples in a time-controlled manner and method for storing samples in a time-controlled manner

Номер: US20140030802A1

Автор: Gavin Clarke, Klaus-Guenter EBERLE

Принадлежит: Andreas Hettich GmbH and Co KG

The invention relates to an air-conditioning space ( 10 ) for storing samples in a time-controlled manner, comprising a device ( 22 ) for automatically feeding sample containers ( 18 ) into a climatically sealed space ( 12 ) having at least one wall ( 43 ), into which a sample container ( 18 ) can be inserted into the climatically sealed space ( 12 ) through an opening ( 40, 42 ), wherein the feed device ( 22 ) has at least one drive and control unit, and an incubator receptacle ( 30 ) for receiving the samples ( 18 ) is provided inside the climatically sealed space ( 12 ). The invention is distinguished by the fact that the feed device has an automatic feed arm ( 22, 24 ) which grips a sample container ( 18 ) from a receiving position outside the climatically sealed space ( 12 ) and deposits the sample container ( 18 ) there in a clear deposit position in an incubator receptacle ( 30 ).

Подробнее

Номер записи: 87

13-02-2014 дата публикации

Microplate reader with lid lifter for microplates

Номер: US20140045210A1

Автор: Friedrich Menges, Gyoergy Wenczel, Harald Gebetsroither

Принадлежит: TECAN TRADING AG

Microplate reader with optical measuring/detection device has housing, a microplate support and a moving unit. The moving unit moves the microplate support out and into the housing and horizontally within the housing. The reader has an integrated lid holding apparatus within the housing for lifting and placing a microplate lid on the microplate. The lid holding apparatus moves the microplate lid and/or the microplate support for moving the microplate in one respective vertical direction. A method for optically measuring a microplate in such a microplate reader places a covered microplate on the microplate support, retracts it into the housing, lifts the lid from the microplate, measures the microplate with the lifted lid, replaces the lid, and extends the support and the covered microplate out of the housing.

Подробнее

Номер записи: 88

06-03-2014 дата публикации

Sample processing apparatus and sample processing method

Номер: US20140064019A1

Автор: Takaaki Nagai, Yuuichi Hamada

Принадлежит: Sysmex Corp

A sample processing apparatus comprising a controller; an agitating section configured to agitate a sample in a sample tube; and a processing section configured to process the agitated sample, wherein the controller is configured to control the agitating section to agitate a sample in a first type of sample tube under a first agitation condition, and to control the agitating section to agitate a sample in a second type of sample tube, which contains a sample of lower volume than the first type of sample tube, under a second agitation condition different from the first agitation condition.

Подробнее

Номер записи: 89

13-03-2014 дата публикации

Apparatus for marking histology embedding cassettes

Номер: US20140071190A1

Автор: Mario Cinti

Принадлежит: Individual

A marking apparatus for marking histology embedding cassettes includes a marking device for marking plastic surfaces, a gripping means to grip and release a cassette, and a movement organ to rotate the gripping means with respect to a first rotation axis perpendicular to a second rotation axis. The first axis is arranged such that it is situated in an ideal plane that is parallel to and interposed between the ideal planes in which the perpendicular surfaces of a cassette, gripped by the gripping means, are located, so that, upon rotation with respect to the first axis the first and the second perpendicular surfaces can alternately be located in front of the marking device. The second axis being arranged with respect to the gripping means such that, upon rotation with respect to the second axis, the oblique surface of the cassette can be in front of the marking device.

Подробнее

Номер записи: 90

13-03-2014 дата публикации

Systems and methods for multi-analysis

Номер: US20140073043A1

Автор: Elizabeth A. Holmes

Принадлежит: Theranos Inc

Systems and methods are provided for sample processing. A device may be provided, capable of receiving the sample, and performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing multiple assays. The device may comprise one or more modules that may be capable of performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing the steps using a small volume of sample.

Подробнее

Номер записи: 91

20-03-2014 дата публикации

Flow passage control mechanism for microchip

Номер: US20140079605A1

Автор: Hisashi Hagiwara, Minoru Asogawa, Tohru Hiramatsu

Принадлежит: NEC Corp

A channel control mechanism for a microchip has a laminated structure formed of members including elastic members, and includes: a sample reservoir for packing a sample therein; a reaction reservoir in which mixture and reaction of the sample are performed; and a channel formed in a middle layer of the laminated structure, for bringing the sample reservoir and the reaction reservoir into communication with each other. The channel control mechanism performs the reaction and analysis in such a manner that the sample is delivered into the reaction reservoir through the channel. A shutter channel (pressurizing channel) is provided in a layer different from a layer in which the channel is formed so that the pressurizing channel partially overlaps the channel. The channel is closed through applying a pressurized medium to the shutter channel (pressurizing channel), and the channel is opened through releasing a pressure of the pressurized medium.

Подробнее

Номер записи: 92

20-03-2014 дата публикации

Processing Apparatus Fabrication

Номер: US20140079608A1

Автор: James M. Pinchot

Принадлежит: JMP Laboratories Inc

A processing apparatus that is formed from a plurality of metal layers that are stacked and aligned together and then connected together to form one or more portions of the processing apparatus.

Подробнее

Номер записи: 93

20-03-2014 дата публикации

Automated Sample Workcell and Method of Operation

Номер: US20140080693A1

Автор: Joerg Haechler

Принадлежит: Roche Diagnostics Operations Inc

Illustrative embodiments of automated sample workcells and methods of operation are disclosed. The methods may include receiving a first plurality of samples, each of the first plurality of samples being linked to a requested analysis selected from among a plurality of analysis types; assigning at least one centrifugation parameter to each of the first plurality of samples in response to the requested analysis linked to that sample; loading a second plurality of samples into a centrifuge, the second plurality of samples being selected from among the first plurality of samples and comprising samples that have been assigned at least two different centrifugation parameters; determining a centrifugation parameter of highest centrifugation intensity from among the at least two different centrifugation parameters assigned to samples in the second plurality of samples; and centrifuging the second plurality of samples according to a centrifugation protocol comprising the centrifugation parameter of highest centrifugation intensity.

Подробнее

Номер записи: 94

27-03-2014 дата публикации

The Use of Microfluidic Systems in the Electrochemical Detection of Target Analytes

Номер: US20140087374A1

Автор: Jon Faiz Kayyem

Принадлежит: Jon Faiz Kayyem

The invention relates generally to methods and apparatus for conducting analyses, particularly microfluidic devices for the detection of target analytes.

Подробнее

Номер записи: 95

03-04-2014 дата публикации

Valved, Microwell Cell-Culture Device And Method

Номер: US20140090735A1

Автор: Paul Ju-Sung Hung, Philip Janmin Lee

Принадлежит: EMD Millipore Corp

A valved microfluidics device, microfluidics cell-culture device and system incorporating the devices are disclosed. The valved microfluidics device includes a substrate, a microchannel through which liquid can be moved from one station to another within the device, and a pneumatic microvalve adapted to be switched between open and closed states to control the flow of fluid through a microchannel. The microvalve is formed of three flexible membranes, one of which is responsive to pneumatic pressure applied to the valve and the other two of which deform to produce a more sealable channel cross-section. The cell culture device provides valving to allow controlled loading of cells into the individual well of the device, and exchange of cell-culture components in the wells.

Подробнее

Номер записи: 96

03-04-2014 дата публикации

Specimen storage device, specimen storing method, and rack

Номер: US20140093425A1

Автор: Yuichiro Ohmae

Принадлежит: Sysmex Corp

To provide a specimen storage device capable of preventing liquid such as immersion oil and the like attached to the specimen plate from leaking to the outside of the rack and capable of enhancing the operation efficiency by automating the supply and discharge of the rack. Provided is a specimen storage device which stores a imaged specimen plate in a bottomed-shaped rack having an opening at an upper part, the specimen storage device including a rack transport mechanism which transports the rack with the opening directed upward, and a specimen transport mechanism which transports the specimen in an up-down direction, wherein the rack transport mechanism transports the rack to a predetermined specimen storage position, and the specimen transport mechanism stores the specimen to the rack positioned at the specimen storage position from above the rack.

Подробнее

Номер записи: 97

03-04-2014 дата публикации

Laboratory Machine and Method for the Automatic Treatment of Laboratory Samples

Номер: US20140094971A1

Автор: Andreas Thieme, Claas Huesmann, Harald Pohl, Judith Lucke, Stefan Roth

Принадлежит: Eppendorf SE

The invention relates to a program-controlled laboratory machine and to a method for the automatic program-controlled treatment of laboratory samples. The laboratory machine has a display having a first display area, via which program parameters that are required by the user are input, and has a second display area in which these input program parameters are shown. The performance of the treatment is effected automatically using the program parameters that are required by the user.

Подробнее

Номер записи: 98

02-01-2020 дата публикации

EVAPORATION-CONTROLLING CONTAINER INSERTS

Номер: US20200001258A1

Автор: Knight Byron J.

Принадлежит: GEN-PROBE INCORPORATED

An apparatus configured for mixing the contents of one or more fluid containers includes a fluid container support platform configured to hold one or more fluid containers. The fluid container support platform is configured to index the container to one or more specified locations and to be moved in an orbital path about an orbital center independently of the rotation about the central axis of rotation. The apparatus further includes an indexing drive system configured to effect indexing movement of the container support platform and a vortex drive system configured to effect powered orbital movement of the container support platform about the orbital center. An evaporation limiting insert placed within containers reduces exposure of the fluid contents of the container to atmospheric air, thereby reducing susceptibility of the fluid contents to evaporation. 1. A method for removing fluid contents of a container while minimizing evaporation of the fluid contents from the container , the method comprising:a) inserting an evaporation-limiting insert into an opening of a neck of the container, the evaporation-limiting insert comprising a hollow tubular body configured to extend into the container from the neck of the container, the tubular body including a plurality of holes formed through a wall of the tubular body and distributed along at least a portion of the length of the tubular body, andb) after step a), inserting a portion of a fluid transfer apparatus through the opening of the container and into the tubular body of the evaporation-limiting and withdrawing a portion of the fluid contents from the container with the fluid transfer apparatus.2. The method of claim 1 , wherein the fluid transfer apparatus comprises a robotic pipettor claim 1 , and step b) comprises inserting a pipette tip associated with the robotic pipettor through the opening of the container and into the tubular body of the evaporation-limiting insert and aspirating a portion of the fluid ...

Подробнее

Номер записи: 99

02-01-2020 дата публикации

MAGNETIC SEPARATION DEVICE AND METHOD OF USE

Номер: US20200001298A1

Автор: Zhou Yuchen

Принадлежит:

The current invention relates to the method and apparatus to magnetically separate biological entities with magnetic labels from a fluid sample. The claimed magnetic separation device removes biological entities with magnetic labels from its fluidic solution by using a soft-magnetic center pole with two soft-magnetic side poles. The claimed device further includes processes to dissociate entities conglomerate after magnetic separation. 1. A device for separating biological entities comprising:a magnetic field source having a first surface and a second surface;a soft magnetic center pole having a first end contacting said first surface, and a tip end tapering away from said first end, thereby concentrating magnetic flux from said first surface towards said tip end;a first soft magnetic side pole having a first base end and a second end;a second soft magnetic side pole having a second base end and a third end;a channel contacting said tip end contains a fluidic sample comprising said biological entities, thereby causing separation of said biological entities bound with magnetic labels towards said tip end;wherein said first and second base ends contact said second surface;wherein said second and third ends are located on opposing sides of said tip end;wherein said magnetic flux from said tip end divides into each of said second and third ends, thereby forming a flux closure within said center pole and said first and second side poles; andwherein said biological entities bound with magnetic labels are removed from said channel after separating said channel from said tip end.2. The device according to claim 1 , wherein said magnetic field source comprises a permanent magnet having a first polarization surface contacting a top surface of a soft magnetic shield claim 1 , and a second polarization surface opposing said first polarization surface claim 1 , wherein said first surface is said second polarization surface and said second surface is said top surface.3. The ...

Подробнее

Номер записи: 100