МНОГОТОЧЕЧНЫЙ МНОГОПАРАМЕТРИЧЕСКИЙ ВОЛОКОННО-ОПТИЧЕСКИЙ ДАТЧИК БОКОВОГО ОСВЕЩЕНИЯ

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Способ определения характеристик оптического канала передачи информационного сигнала включает в себя измерение затухания оптического канала от источника оптического излучения до приемника оптического излучения. При этом производят перемещение лазерного пучка согласованно с линейным перемещением приемника, фиксируют расстояние от оси лазерного пучка до выгорающего материала. На фиксированной длине волны источника оптического излучения предварительно регистрируют значение сигнала, соответствующее уровню мощности лазерного излучения при отсутствии потока воздушной плазмы, далее регистрируют значения сигналов в присутствии плазмы, которое соответствует уровню мощности лазерного излучения, прошедшего через слой толщиной воздушной плазмы и при фиксированном расстоянии, и регистрируют значение сигнала, соответствующее уровню мощности лазерного излучения, прошедшего поглощающий слой плазмы исследуемого выгорающего материала. Технический результат заключается в обеспечении возможности определения ...

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Настоящее изобретение относится к электронному курительному изделию и, в частности, к принадлежности для сбора данных о режиме курения, закрепленной к корпусу электронной сигареты. Принадлежность для электронного курительного изделия, которая включает в себя полый корпус с имеющимися у него внутренней и внешней поверхностями и датчик, расположенный в корпусе. Датчик способен обнаруживать излучение, создаваемое электронным курительным изделием. Процессор встроен в корпус и способен формировать данные о режиме курения на основе излучения. Дисплей формирует вывод на основе данных о режиме курения, полученных от процессора. Технический результат заключается в возможности измерения параметров режима курения. 2 н. и 15 з.п. ф-лы, 3 ил.

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СПОСОБ И УСТРОЙСТВО ДЛЯ КОНТРОЛЯ ШИН НА ЛИНИИ ДЛЯ ПРОИЗВОДСТВА ШИН

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Изобретение относится к области исследования поверхности металлов и полупроводников и касается устройства для промера распределения поля инфракрасной поверхностной электромагнитной волны (ПЭВ) над ее треком. Устройство содержит источник монохроматического излучения, элемент преобразования излучения в ПЭВ, твердотельный образец с направляющей волну плоской поверхностью и перемещаемую вдоль трека платформу. На платформе установлен фокусирующий объектив, фотоприемник, измерительный прибор и стойка. На стойке установлены амортизированная пружинами рамка и регулировочный микровинт, сочлененный с размещенной внутри рамки площадкой, несущей элемент преобразования ПЭВ в ОВ. Пружины, упираясь в стойку, поджимают рамку к образцу, а сама рамка опирается на поверхность образца перемещающимися по ней упорами. Элемент преобразования излучения в ПЭВ выполнен в виде сектора цилиндра, ось которого ориентирована перпендикулярно плоскости падения излучения, а выпуклая поверхность этого элемента, способная ...

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Настоящее устройство относится к области проверки и измерений оптических параметров и предназначено для измерения коэффициентов диффузного и зеркального отражений от внутренней поверхности цилиндра. Задачей полезной модели является создание стенда, обеспечивающего расширение функциональных возможностей для измерения коэффициентов диффузного и зеркального отражений для закрытых поверхностей цилиндра. Техническим результатом, позволяющим решить указанную задачу, является размещение излучателя и (i+1) фотоприемников на матрице внутри цилиндра. Стенд для измерения коэффициентов диффузного и зеркального отражений содержит излучатель с коллиматором излучения и поворотным устройством, которые смонтированы на направляющей с соединительными проводами, соединенной с матрицей фотоприемников, размещенных на светопоглощающем экране по всей длине цилиндра, отличается тем, что излучатель и (i+1) фотоприемников на матрице размещаются внутри цилиндра, причем измеряется интенсивность пучка от отражения на ...

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Изобретение относится к области измерительной техники и касается способа спектральной диагностики оптических осей и типов колебательных центров в кристаллах с водородными связями. Способ включает в себя измерение для исследуемого кристалла термостимулированных токов деполяризации и получение инфракрасных спектров пропускания и поглощения в различных направлениях. По полученным данным определяют ширину запрещённой зоны для каждого кристалла, выделяют протонную составляющую в колебательных центрах и для каждой линии, соответствующей определённому колебательному центру, определяют энергию активации, длину волны и волновое число, по величине и наличию которых в данном направлении определяют типы колебательных центров и направление оптических осей. Технический результат заключается в повышении точности, экспрессности и достоверности измерений. 7 ил., 3 табл.

УСТРОЙСТВО ФОРМИРОВАНИЯ ИЗОБРАЖЕНИЯ И СПОСОБ ФОРМИРОВАНИЯ ИЗОБРАЖЕНИЯ С ИСПОЛЬЗОВАНИЕМ ОПТИЧЕСКОЙ КОГЕРЕНТНОЙ ТОМОГРАФИИ

Изобретение относится к формированию изображения с использованием оптической когерентной томографии в Фурье-области. Устройство содержит первый переключающий блок 17, осуществляющий переключение между первым состоянием, в котором обратный луч 12 объединяется с опорным лучом (состояние, в котором обратный луч 12 проводится к объединяющему блоку 22), и вторым состоянием, отличающимся от первого состояния (состоянием, в котором путь луча для обратного луча 12 блокируется или изменяется). Управляющий блок 18 управляет переключающим блоком 17 для изменения первого и второго состояний. Блок 19 сбора интерферометрической информации осуществляет сбор интерферометрической информации об обратном луче 12 и опорном луче 14 с использованием опорного луча 14 или обратного луча 12, обнаруженного обнаруживающим блоком 16 во втором состоянии, и объединенного луча 15. Изобретение обеспечивает получение томографического изображения с высоким разрешением за счет удаления шумов, обусловленных автокорреляционной ...

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Изобретение относится к способу оценки концентрации компонентов серы в бензине. Предложен способ оценки концентрации компонентов серы в бензине, который содержит компоненты серы и ароматические компоненты, при этом способ содержит: (A1) удаление части бензина путем превращения в газ для снижения соотношения концентрации ароматических компонентов относительно концентрации компонентов серы в бензине, причем бензин превращают в газ в концентрации 8,0 об. % или более, (A2) измерение значений, связанных с показателем преломления бензина, и (A3) оценку концентрации компонентов серы в бензине на основе значений, связанных с показателем преломления. Также предложен способ для восстановления каталитического нейтрализатора отработавших газов, который очищает отработавшие газы, выбрасываемые двигателем внутреннего сгорания, в котором сжигают бензин. Технический результат заключается в оценке концентрации компонентов серы в бензине с высокой точностью. 2 н. и 5 з.п. ф-лы, 5 ил., 2 табл., 3 пр.

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Изобретение относится к способам измерения массовой концентрации ионов бария фотоколориметрическим методом. Способ включает отбор проб, приготовление вспомогательного и градуировочного растворов, построение градуировочной характеристики, определение массовой концентрации ионов бария. В качестве вспомогательного раствора готовят осадительный и холостой растворы, готовят градуировочный раствор с массовой концентрацией ионов бария от 5,0 до 100,0 мг/дм3, производят измерение оптической плотности при длине волны 440 нм, перед построением градуировочной характеристики проводят проверку линейной зависимости оптической плотности, построение градуировочной характеристики выполняют методом наименьших квадратов, отобранную пробу водонефтяной смеси выдерживают до достижения комнатной температуры помещения, после расслоения пробы отделяют пластовую воду от нефти, отбирают 5 см3 пробы пластовой воды, переносят ее в мерную емкость вместимостью 50 см3, добавляют 200 мкдм3 этилового спирта, 5 см3 осадительной ...

ПОПУЛЯЦИИ СПЕРМАТОЗОИДОВ, НЕСУЩИХ Х-ХРОМОСОМУ И НЕСУЩИХ У-ХРОМОСОМУ, С ВЫСОКОЙ СТЕПЕНЬЮ ОЧИСТКИ

... 1. Способ разделения клеток спермы, несущих Х-хромосому, и клеток спермы, несущих Y-хромосому, содержащий следующие этапы: а. отбор клеток спермы от самца определенного вида млекопитающих; b. определение характеристики, дифференцирующей половые признаки указанных клеток спермы; с. дифференцирование клеток спермы с учетом указанной характеристики дифференцирования половых признаков; d. разделение дифференцированных клеток спермы на популяции, несущие Х-хромосому, и популяции, несущие Y-хромосому; и е. получение популяций клеток спермы, несущих X-хромосому и несущих Y-хромосому, со степенью чистоты выше, чем 90% для каждой. 2. Способ разделения клеток спермы, несущих Х-хромосому, и клеток спермы, несущих Y-хромосому, по п.1, отличающийся тем, что этап дифференцирования клеток с учетом характеристики дифференцирования половых признаков, содержит оценку количества ДНК в ядрах клеток спермы. 3. Способ разделения клеток спермы, несущих Х-хромосому, и клеток спермы, несущих Y-хромосому, по п.1 ...

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Изобретение относится к эксплуатации автотракторной техники, а в частности к способам контроля качества топлива на содержание воды и подготовки топлива к сгоранию. Заявленное устройство для определения содержания воды в дизельном топливе включает излучатель световых волн, приемник световых волн, измерительную емкость, блок управления, канал подвода топлива, пьезоэлектрический датчик температуры, обратный клапан, жиклерное отверстие и оптические волокна, ориентированные по потоку движения топлива под углом 90° и обвитые тонкоскрученным волокном в виде спирали из водопоглощающего материала. При присутствии в топливе воды происходит ее диффузия в тонкоскрученные волокна из водопоглощающего материала, которые вызывают изменение оптических свойств волокна. Пьезоэлектрический датчик температуры определяет температуру тестируемого топлива и служит корректировочным коэффициентом для обработки блоком управления. Технический результат - возможность оперативного анализа состояния дизельного топлива ...

Способ профилирования состава при эпитаксиальном формировании полупроводниковой структуры на основе твердых растворов

Изобретение относится к профилированию состава твердых растворов гетероэпитаксиальных структур при их росте. Способ при формировании структуры типа АВна основе теллуридов элементов второй группы таблицы Менделеева включает измерения эллипсометрических параметров Ψ и Δ на одной длине волны света видимой области спектра. Перед измерениями, проводимыми в отношении структуры, профиль которой получают, посредством эллипсометрии определяют скорость роста структуры. При осуществлении измерений, проводимых в отношении структуры, профиль которой получают, задают, исходя из скорости роста, временной интервал измерений, при котором толщина слоя, выросшего в течение временного интервала между j-м и (j+1)-м измерениями, при постоянстве его состава и оптических свойств равна значению от 0,2 до 1,5 нм, включая указанные значения. Затем проводят с погрешностью не более 0,01° и при угле падения света ϕ со значением в диапазоне от 65 до 70° измерения эллипсометрических параметров Ψи Δ, фиксируя время измерения ...

Способ и устройство для мониторинга состояния здоровья растений

Группа изобретений относится к области интеллектуального сельского хозяйства. Техническим результатом является увеличение контролируемой области посадок и повышение скорости обследования растений. Группа изобретений представляет собой способ контроля состояния здоровья растений, включающий в себя: выполнение первого определения в соответствии с информацией о состоянии здоровья растений; когда результатом определения является то, что существует риск плохого состояния здоровья растений, выполнение второго определения в соответствии со второй информацией о состоянии здоровья растений в ориентации, где находится по меньшей мере одно растение с риском плохого состояния здоровья растений, чтобы точно получить информацию о состоянии здоровья растений, и устройство, реализующее этот способ для мониторинга состояния здоровья растений. 2 н. и 13 з.п. ф-лы, 8 ил.

Способ определения характеристик оптического канала передачи информационного сигнала

Messsystem zum Erfassen einer Konzentration einer Zielerfassungssubstanz in einem Medium

Messsystem zum Erfassen einer Konzentration einer Zielerfassungssubstanz in einem Medium (200), mit:- einem optischen Aktuator (100), der einen optischen Reiz in einer Zielerfassungssubstanz setzt, die sich in einem Medium (200) befindet;- einem Fotodetektor (300), der in Abhängigkeit von der Konzentration der Zielerfassungssubstanz im Medium (200) eine optische Antwort ausgibt, wobei ein elektrisches Signal mit einer Snap-Back-Form im Ansprechen auf die optische Antwort erzeugt wird, wenn sich ein Ansteuerstrom für den Fotodetektor (300) ändert;- einem Verstärker (400), der das vom Fotodetektor (300) ausgehende elektrische Signal verstärkt und dieses verstärkte Signal als positive Rückkopplung an den optischen Aktuator (100) gibt; und- einer Erfassungseinheit (500), die das vom Fotodetektor (300) als Ergebnis des Ansprechens auf die Konzentration der Zielerfassungssubstanz im Medium (200) erzeugte elektrische Signal erfasst, wobei das elektrische Signal infolge der positiven Rückkopplung ...

INDIREKTE KOLORIMETRISCHE DETEKTION EINES ANALYTEN IN EINER PROBE UNTER ZUHILFENAHME DES VERHAELTNISSES VON LICHTSIGNALEN.

Optisches Verfahren zum Bestimmen mechanischer Eigenschaften eines Materials

PROCESS FOR DETERMINING THE BASIS WEIGHT OF A LOW ATOMIC NUMBER MATERIAL IN A MIXTURE WITH A HIGHER ATOMIC NUMBER MATERIAL

Vorrichtung zum photothermischen Prüfen einer Oberfläche

Concentration value determining device for magneto-optic substance i.e. glucose, in aqueous liquid in e.g. eye, has evaluation unit determining concentration value of magneto-optic substance in medium on basis of determined phase relation

The device (1) has a detection unit (38) that is provided for detecting two electromagnetic radiations that are radiated by a light source (10) after partial radiography of a medium with applied magnetic field (44). A determination unit (40) is provided for determining a phase relation between the two detected electromagnetic radiations. An evaluation unit (46) is provided for determining a concentration value of a magneto-optic substance in the medium on the basis of the determined phase relation. Independent claims are also included for the following: (1) a method for determining concentration value of a magneto-optic substance in a medium (2) a computer program product for performing a method for determining concentration value of a magneto-optic substance in a medium.

Combined acoustic excitation and standoff chemical sensing for remote detection of buried explosive charges

Road surface condition monitoring apparatus

System and method of distributed fiber optic sensing including integrated reference path

Method and apparatus for oil condition monitoring

MESSEINRICHTUNGEN UND ROHRANSCHLUSS SOWIE VERFAHREN ZUR HERSTELLUNG EINER MESSEINRICHTUNG UND VERFAHREN ZUR VERBINDUNG VON ROHREN MIT EINER MESSEINRICHTUNG BZW. ZUR HERSTELLUNG VON ROHRANSCHLUESSEN

METHOD FOR DETECTING DISCONTINUITIES IN A TRANSLUCENT ARTICLE

Verfahren zu einer zerstörungsfreien Detektion von geometrischen Diskontinuitäten in einem lichtdurchlässigen Werkstück, wobei von zumindest einer Lichtquelle emittierte Lichtstrahlen auf das Werkstück gerichtet werden, sodass eine erste Teilmenge der Lichtstrahlen unter einem ersten Reflexionswinkel an der Werkstückoberfläche reflektiert wird und eine zweite Teilmenge der Lichtstrahlen unter einem ersten Brechungswinkel durch das Werkstück transmittiert wird, wobei eine dritte Teilmenge an Lichtstrahlen durch die Diskontinuitäten unter einem zweiten Reflexionswinkel an der Diskontinuitätenoberfläche der Diskontinuität reflektiert wird und durch die Diskontinuitäten unter einem zweiten Brechungswinkel transmittiert wird, wobei die reflektierten Lichtstrahlen durch eine Hyperspektralkamera und/oder monochromatische Lichtstrahlen als transmittierte Lichtstrahlen mittels einer optischen Kamera aufgenommen werden.

COMBINED PHOTO-ACOUSTIC AND ULTRASONIC REPRESENTATION SYSTEM

USE OF A MICRO-FLUID DEVICE FOR IDENTIFICATION, QUANTIFICATION AND AUTHENTIFIZIERUNG LATENT MARKER

Vorrichtung und Verfahren zur Zählung und/oder Messung von Partikeln in einem Fluidstrom

Die Erfindung betrifft eine Vorrichtung und ein Verfahren zur Zählung und/oder Messung von Partikeln (1) in einem Fluidstrom (3). Die Vorrichtung weist eine Lichtquelle (4) zur Durchleuchtung des Fluidstroms (3) in einem Bereich eines Messkanals (2), der vom Fluidstrom (3) durchflossen wird, und einen Lichtsensor (6) mit einer Vielzahl an Sensorelementen (7), die in dem von der Lichtquelle (4) ausgestrahlten Lichtbündel und an der der Lichtquelle (4) gegenüberliegenden Seiten des Messkanals (2) angeordnet sind, auf. Es ist eine Auswerteeinheit (12) vorgesehen, die eine Vielzahl an zeitlich aufeinanderfolgenden Sensormessungen (13) zu einem Sensorbild (9) zusammensetzt und zur Messung und/oder Zählung der Partikel (1) Interferenzmuster (10) in dem Sensorbild (9), die von den Partikeln (1) verursacht werden, auswertet.

Vorrichtung und Verfahren zur Ermittlung der Anzahl an Feststoffpartikeln in einem Fluidstrom

Vorrichtung und Verfahren zur Ermittlung der Anzahl an Feststoffpartikeln in einem Fluidstrom, insbesondere in Abgasen von Verbrennungskraftmotoren. Die Vorrichtung weist einen Messkanal (1) für den zu messenden Fluidstrom, eine Sättigungseinheit (2) zu Sättigung des Fluids mit Dämpfen eines Betriebsmittels (3), eine Kondensationseinheit (4) zum Abkühlen des Fluidstroms und eine Zähleinheit (5) zum Zählen der beim Abkühlen an den Partikeln gebildeten Kondensattröpfchen (6) auf. Die die Zähleinheit (5) weist eine Beleuchtungsvorrichtung (7), zumindest einen Lichtsensor (9) und eine mit dem Lichtsensor (9) verbundene Recheneinheit (11) zur Ermittlung der Anzahl an Feststoffpartikeln auf. Die Beleuchtungsvorrichtung (7) erzeugt einen an einer Schnittebene durch den Messkanal (1) angeordneten Lichtteppich (8), der eine Messfläche definiert, die sich im Wesentlichen über den gesamten Querschnittsbereich des Messkanals (1) erstreckt. Der Lichtsensor (9) weist zur Abtastung der gesamten Erstreckung ...

DEVICE FOR PHOTO-THERMAL EXAMINING OF A SURFACE

FORECAST OF THE CHARACTERISTICS OF A PLATE USING A SPECTROSCOPIC PROCEDURE IN COMBINATION WITH MULTI-VARIABLE MEASURING

Protected item including a protective coating

There is disclosed a protected item including an item that needs protection and a protective coating having a hardness of at least about 8 on the Mohs scale. The protected item includes a light transmission in part or all of the visible wavelength of at least about 60% and a light reflection in the visible wavelength of about 4% or less.

Optical apparatus and associated devices for biometric identification and health status determination

The present disclosure provides techniques and apparatus for capturing an image of a person's retina fundus, identifying the person, accessing various electronic records (including health records) or accounts or devices associated with the person, determining the person's predisposition to certain diseases, and/or diagnosing health issues of the person. Some embodiments provide imaging apparatus having one or more imaging devices for capturing one or more images of a person' s eye(s). Imaging apparatus described herein may include electronics for analyzing and/or exchanging captured image and/or health data with other devices. In accordance with various embodiments, imaging apparatus described herein may be alternatively or additionally configured for biometric identification and/or health status determination techniques, as described herein.

Method for detecting solid-liquid distribution in solid-liquid separation column of solid-liquid separation device and detection device

Provided are a method and a device for detecting a solid-liquid distribution in a solid-liquid separation column of a freeze concentration device used in a freeze concentration method. A device for detecting the solid-liquid distribution in a solid-liquid separation column in a solid-liquid separation device is provided with a light irradiation means for irradiating the inside of a solid-liquid separation column in a freeze concentration device with visible light, a photographing means for photographing the inside of the solid-liquid separation column irradiated with visible light by the light irradiation means, a movement means for moving the photographing means in the vertical direction of the solid-liquid separation column, an image analysis means for analyzing image data photographed by the photographing means and an evaluation means for evaluating the solid-liquid distribution state in the solid-liquid separation column on the basis of analysis results of the image analysis means.

Method for measurement of calcium ions

The present invention relates to a reagent for determination of calcium and to a determination method using that reagent. More particularly, it relates to a reagent for determination of calcium comprising a mono-nitro substituted BAPTA-type chelator (BAPTA =1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid). A determination method which permits accurate determination of calcium in a sample, such as a blood sample (e.g. whole blood, plasma or serum) or any other aqueous liquid sample (e.g. cerebrospinal fluid, lymph, salivary juice or urine) and thus is especially useful for clinical diagnoses as described.

A stable isotope measurement method for spectrometrically analyzing an isotopic gas and method of judging absorption capacity of carbon dioxide absorbent

COMPUTERIZED ANALYSIS FOR ABNORMAL CELLS IN A CELL BLOCK

System and method for detecting biofilm growth in water systems

A system and method for monitoring or detecting a level of biofilm growth in a fluid system and controlling operating parameters of the fluid system based a measured level of growth. The monitoring system and method comprises a dye injection system for periodically injecting dye into a portion of fluid from the fluid system, passing the portion of fluid though a narrow lumen tube to achieve laminar flow and using a light source and optical sensor to detect a transmission or emission indicating a level of biofilm growth in the tube corresponding to a level of growth on components in the fluid system. Information based upon the measurements or calculations made by the monitoring system may be used to manually or automatically alter various operating parameters to control the fluid system and aid in maintaining stable operation of the fluid system within preferred specifications.

System and method for detecting biofilm growth in water systems

A system and method for monitoring or detecting a level of biofilm growth in a fluid system and controlling operating parameters of the fluid system based a measured level of growth. The monitoring system and method comprises a dye injection system for periodically injecting dye into a portion of fluid from the fluid system, passing the portion of fluid though a narrow lumen tube to achieve laminar flow and using a light source and optical sensor to detect a transmission or emission indicating a level of biofilm growth in the tube corresponding to a level of growth on components in the fluid system. Information based upon the measurements or calculations made by the monitoring system may be used to manually or automatically alter various operating parameters to control the fluid system and aid in maintaining stable operation of the fluid system within preferred specifications.

Systems and methods for measuring downhole fluid characteristics in drilling fluids

Disclosed are systems and methods for monitoring drilling fluids. One system includes a flow path containing a fluid having at least one component present therein, and a movable housing having at least one optical computing device configured to move with the movable housing along a detection path, the at least one optical computing device including at least one integrated computational element (ICE) configured to optically interact with the fluid over the detection path, wherein the at least one ICE is configured to detect a characteristic of the at least one component and generate an output signal corresponding to the characteristic.

Improving weather forecasts through post-processing

A method for calibrating forecasts involving temperature, precipitation, and other weather related variables is provided. In an embodiment historical ensemble-based forecasts and historical observations are received by an agricultural intelligence computing system. Historical differences are determined between the forecasts and the observations corresponding to the forecasts and stored in the volatile memory of the agricultural intelligence computing system. The agricultural intelligence computing system receives current ensemble-based forecasts and a request for improved forecasts. The agricultural intelligence computing system retrieves the historical differences and uses a combination of the historical differences and the current ensemble-based forecasts to create probability distributions for the weather for each lead day. The agricultural intelligence computing system then samples from the probability distributions to create improved ensemble-based forecasts at the requested location ...

Devices for optically determining a characteristic of a substance

Optical computing devices are disclosed. One exemplary optical computing device (300) includes an electromagnetic radiation source (308) configured to optically interact with a sample (306) and at least two integrated computational elements (302, 304). The at least two integrated computational elements are configured to produce optically interacted light (314), and at least one of the at least two integrated computational elements is configured to be disassociated with a characteristic of the sample. The optical computing device further includes a first detector (316) arranged to receive the optically interacted light (314) from the at least two integrated computational elements and thereby generate a first signal corresponding to the characteristic of the sample.

Estimating intra-field properties within a field using hyperspectral remote sensing

A method for estimating soil properties within a field using hyperspectral remotely sensed data. A soil preprocessing module receives soil spectrum data records that represent a mean soil spectrum of a specific geo-location of a specified area of land. The soil preprocessing module removes interference signals and creates a set of one or more spectral bands. A soil regression module inputs the one or more soil spectral bands and predicts soil property datasets. The soil property datasets include specific soil properties relevant to determining fertility of the soil or soil property levels that may influence soil management at a specific geo-location. The soil regression module selects multiple specific soil property datasets that best represent the existing soil properties including soil properties predicted and the spectral band data used to determine the soil properties. The soil regression module sends this predicted data to a soil model database.

DETECTING THE DECOMPOSITION OF ENZYMES IN A TEST ELEMENT BY MEANS OF CONTROLLED RELEASE OF PROTECTED ANALYTE

The present invention relates to diagnostic element for determining at least one analyte and an analytical measuring device comprising such a diagnostic element. The invention further relates to a method for determining an analyte, to a method for correcting a signal generated by an analyte, and to a method for checking the detection optics of an analytical measuring device using the diagnostic element. The invention finally relates to a system for the controlled release of a reagent, and to the use of such a system as a circuit element.

METHODS AND APPARATI FOR NONDESTRUCTIVE DETECTION OF UNDISSOLVED PARTICLES IN A FLUID

The apparati, methods, and computer program products disclosed herein can be used to nondestructively detect undissolved particles, such as glass flakes and/or protein aggregates, in a fluid in a vessel, such as, but not limited to, a fluid that contains a drug.

DEVICE FOR DETECTING AN ANALYTE IN A BODILY FLUID

The invention relates to a device (110) for detecting at least one analyte in a bodily fluid. The device (110) comprises at least one test element (120) having at least one two- dimensional analysis area (136). The device (110) further comprises at least one spatial optical detector (138) having a plurality of pixels (146). The detector (138) is set up for reproducing at least one part of the test element (120) on an image area (148). At least one part of the analysis area (136) is thereby reproduced on an analysis image area (150). The detector (138) is adapted to the test element (120), such that a prescribable minimum number of pixels (146) is provided for each dimension within the analysis image area (150). The pixels (146) are disposed in a two-dimensional matrix arrangement. The matrix arrangement comprises pixel rows (158) and pixel columns (160), wherein the pixel rows (158) are disposed substantially parallel to a longitudinal axis of the analysis area (136) and/or the analysis ...

RADIATION DETECTOR INCLUDING FIELD EFFECT TRANSISTOR IN RESONANT CAVITY NANOSTRUCTURE

A radiation detection device includes a plurality of field effect transistors (FETs) arranged to form a resonant cavity. The cavity includes a first end and a second end. The plurality of FETs provide an electromagnetic field defining an standing wave oscillating at a resonant frequency defined by a characteristic of the cavity. A radiation input passing through the cavity induces a perturbation of the electromagnetic field.

FIBER LASER FOR ULTRASONIC LASER TESTING

Embodiments of the present invention relates to an improved laser for the optical detection of ultrasound. The primary task of this "first" detection laser is to illuminate the spot where a "second" laser is used to generate ultrasound in the part under test. The scattered light from the first laser is collected and analyzed with an interferometer to demodulate the surface vibrations caused by the return echoes of the ultrasound at the surface of the part. The improved detection laser (first laser) is constructed using a diode- pumped fiber laser to produce a high power single -frequency laser source.

SYSTEM AND METHOD OF DISTRIBUTED FIBER OPTIC SENSING INCLUDING INTEGRATED REFERENCE PATH

An apparatus for estimating a parameter includes: an optical fiber including at least one core configured to transmit an interrogation signal and including a plurality of sensing locations distributed along a measurement length of the optical fiber and configured to reflect light; a reference optical path configured to transmit a reference signal, the reference optical path disposed in a fixed relationship to the at least one core and extending at least substantially parallel to the at least one core, the reference optical path including a reference reflector that defines a cavity length corresponding to the measurement length; a detector configured to receive a reflected return signal; a reference interferometer configured to receive at least a reference signal and generate an interferometric reference signal; and a processor configured to apply the interferometric reference signal to the reflected return signal to compensate for one or more environmental parameters.

SIDE ILLUMINATED MULTI POINT MULTI PARAMETER OPTICAL FIBER SENSOR

A side illuminated multi point multi parameter optical fiber sensor that requires no sensitive coating is provided. This sensor comprises an optical fiber having at least one removed cladding section as the sensitive region, at least one probing light source that side illuminates the fiber, a power supply, a detector, a signal processor and a display. The sensitive optical fiber is optically affected by the presence of a measurand medium that can fluoresce, phosphoresce, absorb and/or scatter the probing light. This probing light is guided by the fiber core towards a detector which measures the light intensity and this light intensity is correlated with a measurand.

AN ARRANGEMENT RELATED TO A GAS SENSOR

The present invention concerns a gas-sensor related arrangement ("A") and more specifically an arrangement which, for its function, utilizes a first (1) light-generating means, a second (2) light-receiving means, and a third (3) means for forming and defining an optical measuring distance between said first and second means through a gas sample, as well as a control unit (20, 123), with associated calculating circuits (30, 125). More specifically, a unit ("E1 ") is to be allotted to a plurality of first electric connector devices or means (4, 4a, 4b), said connector devices being adapted and distributed along a first surface portion (5) of said unit for an electric connecting possibility to other electric connector devices or means ((4), (4a), (4b)) related to a carrier ("B1 "), such as a printed circuit card or board, for said unit. Said first (1) and second (2) means are to be closely related to each other within a "discrete unit" ("EI ") as a first (1a) and a second (2a) surface section ...

PARTICLE DETECTOR, SYSTEM AND METHOD

... ²The invention provides use of one or more emitted beams of radiation (16), for ²example, laser beam(s), in²combination with an image capturing means (14), for example, one or more video ²cameras and/or optical elements to detect particles (30), ²for example, smoke particles, located in an open space (12).²²² ...

PROCESS AND DEVICE FOR DETERMINING MEASURED QUANTITIES BY MEANS OF AN INTEGRATED OPTICAL SENSOR MODULE

PROCESS AND DEVICE FOR DETERMINING MEASURED QUANTITIES BY MEANS OF AN INTEGRATED OPTICAL SENSOR MODULE A method is described that allows a plurality of variables to be measured with the aid of an integrated optical sensor module. Because all the components necessary for carrying out the method are integrated on the same substrate, the sensor becomes small, compact, stable, malfunction-free and economical. The sensor module substantially comprises a sensor field, an analyzer, and an information field. The method comprises making the variables to be measured interact in sensor fields with guided waves, analyzing the effect on the wave, determining from that the value of the measuring variables, and displaying the results in the information field. (Fig. 1) ...

Vorrichtung zur mehrfachen Registrierung von Werten, die durch kolorimetrische oder andere chemische Analysegeräte gemessen werden

METHOD OF MEASURING SAMPLE COMPOSITION

МИКРОЖИДКОСТНОЕ УСТРОЙСТВО ДЛЯ ИДЕНТИФИКАЦИИ, КОЛИЧЕСТВЕННОГО ОПРЕДЕЛЕНИЯ И АУТЕНТИФИКАЦИИ ЛАТЕНТНЫХ МАРКЕРОВ

Предложены устройства и способы для идентификации, аутентификации и количественного определения одного или нескольких скрытых маркеров, содержащихся в материале. Устройство содержит микрожидкостную ячейку, систему переноса жидкости и систему детектора и представляет собой интегральный узел, обеспечивающий автоматизированный способ идентификации in line одного или нескольких материалов, содержащих по меньшей мере один латентный маркер, который может преобразовываться в активную форму. Микрожидкостная ячейка предназначена для приема материала, содержащего латентный маркер, и имеет по меньшей мере один вход для приема одной или нескольких жидкостей и один или несколько выходов, через которые жидкость выходит. Система переноса жидкости в рабочем состоянии соединена с микрожидкостной ячейкой и доставляет жидкости в микрожидкостную ячейку. Система детектора, которая может содержать источник и сенсор, располагается после выходов для детектирования активной формы маркера. С помощью устройства ряд ...

DEVICE FOR DIFFERENTIATION OF ASSYMETRIC PARTICLES

ACCESSORY FOR ELECTRONIC CIGARETTE

Water-pollution microwave active-passive compound detection method and device

Urine detecting device

Full-automatic blood coagulation analyzer and analysis method thereof

Urine detection device

Method and system for estimating annual GPP based on EVI2 season change curve

DEVICE FOR THERMAL MECHANISM Of IMPRESSION, INTENDS FOR NECESSARY CONTROL DUPOSITIONNEMENT Of a PRINT TAPE UNROLLING BETWEEN a ROLLER Of APPUIELASTIQUE AND a THERMAL PRINT HEAD

Picture brightness measuring unit - comprises array of movable lenses and filter with pen recorder output

system and method for image scanning utilizing photosynthesis mechanism

SYSTEM AND METHOD FOR EVALUATING PERFORMANCE OF VEHICLE DISINFECTION DEVICE

A system for evaluating performance of a vehicle disinfection device according to an embodiment of the present invention includes: an evaluation kit comprising at least one of a first kit attached to a plurality of points of a vehicle to be evaluated, applied with disinfection liquid sprayed from the vehicle disinfection device, and including a disinfection liquid responding sheet and a second kit including a microbial carrier which responds to the disinfection liquid; an image analyzer for measuring an application amount of the disinfection liquid based on an image of the first kit passed through the disinfection device; an agitator for neutralizing microorganisms of the second kit passed the disinfection device; a measuring device for measuring the content of the microorganisms by inoculating the solid medium with the neutralized liquid after diluting the neutralized liquid in the agitator or inoculating a cell or developing cell with the liquid; and a determiner for evaluating the performance ...

APPARATUS OF ATTACHMENT AND DETACHMENT ELECTRODES AND ELECTROCHEMICAL CELL FOR MEASUREMENT OF ELECTRODES'S PROPERTIES INCLUDING THE APPARATUS

SAMPLE-TO-ANSWER MICROFLUIDIC CARTRIDGE

ANALYTICAL METHOD AND APPARATUS

A method for analysing function of a biosystem (16) based on analysis of a sample (12) taken from a portion of said biosystem (18); said method comprising exposing said sample to incident energy (10) derived from an energy source (11); receiving radiated energy from said sample consequent to impingement of said incident energy on said sample; passing at least a portion of said radiated energy through a transducer (13) thereby to derive an information signal (15) which characterises an aspect of said sample (12); analysing said information signal to produce biosystem data which can be used to identify said aspect of said sample (12). © KIPO & WIPO 2007 ...

Optical sensor arrangement and method for measuring an observable

aparelho e método de processamento de informação, programa, e, sistema de observação.

METHODS AND DEVICES FOR DETERMINING A CHARACTERISTIC OF A SUBSTANCE OPTICALLY

Se revelan dispositivos informáticos ópticos. Un dispositivo informático óptico ejemplar incluye una fuente de radiación electromagnética configurada para interactuar ópticamente con una muestra y por lo menos dos elementos informáticos integrados. Por lo menos los dos elementos informáticos integrados se pueden configurar para producir luz de interacción óptica, y por lo menos uno de por lo menos los dos elementos informáticos integrados se puede configurar para ser disociados con una característica de la muestra. El dispositivo informático óptico además incluye un primer detector dispuesto para recibir la luz de interacción óptica de por lo menos dos elementos informáticos integrados y así generar una primera señal que corresponde a la característica de la muestra.

METHODS AND DEVICES FOR DETERMINING A CHARACTERISTIC OF A SUBSTANCE OPTICALLY

Se describen dispositivos informáticos ópticos. Un dispositivo óptico informático ejemplar incluye una fuente de radiación electromagnética configurada para interactuar ópticamente con una muestra y primer y segundo elemento computacional integrado dispuestos en canales primarios y de referencia, respectivamente. El primer y segundo elemento computacional integrado producen primera y segunda radiaciones electromagnéticas modificadas, y un detector está dispuesto para recibir la primera y la segunda radiación electromagnética modificada y generar una señal de salida correspondiente a la característica de la muestra.

PROPERTIES PROGNOSTICATION OF CHIPBOARD BY MAKING USE OF SPECTROSCOPIC METHOD COMBINED WITH MULTIVARIANT CALIBRATION

The method is applicable for the determination of theparameters of chipboards. By it the raw timber, respectivelyboards, is spectrometrically analyzed having moisture contentunder 10% and the spectral data are compared with reference datafrom reference material/boards. Control of the variables of theprocess affecting the parameters of the boards is also made byanalyzing the material/boards, the spectral data are related incombinations with the desired parameters and are compared with thereference combinations which are calibrated by known variables bymeans of multivariant analysis.20 claims ...

Apparatus and method for evaluating quality of granular object

A quality evaluation method for granular objects includes the steps of: irradiating (30, 34, 38) the objects from a front side and a back side thereof; taking (31, 35) a reflection light image and a transmission light image from both the front and back sides of the irradiated objects; obtaining (3) optical information of the objects by image-processing the reflection and transmission light images; obtaining (3) shape information of the objects based on the optical information; determining (4) the quality of each of the objects based on the optical information and the shape information; and counting (4) the numbers of the objects per quality and obtaining ratios of the objects per quality against the total number of the objects. Samples images of the objects per quality are prepared. The numbers and ratios of the objects per quality and the sample images are displayed (6) or printed out (5). One side of the granular objects may be irradiated by separate light sources (34A-34D) that are turned ...

OPTICAL MEASURING APPARATUS AND METHOD FOR THE ANALYSIS OF SAMPLES CONTAINED IN LIQUID DROPS

An optical measuring apparatus (1) is configured for the analysis of samples contained in liquid drops (2) provided by a liquid handling system (3) that comprises at least one liquid handling tip (4). The optical measuring apparatus (1) comprises a light source (8) for irradiating the liquid drop (2); a detector (10) for measuring sample light (11); an optics system (43) with first optical elements (18) for transmit- ting irradiation light (9), and a processor (13) for accepting and processing the measurement signals (12). The liquid drop (2) is suspended at the liquid handling orifice (6) of the liquid handling tip (4) in a position where the liquid drop (2) is penetrated by a first optical axis (14) defined by the light source (8) and the first optical elements (18). The liquid drop (2) is physically touched only by the liquid handling tip (4) of the liquid handling system (3) and the liquid sample (30) inside the liquid handling tip (4). The optical measuring apparatus (1) comprises ...

METHOD AND APPARATUS FOR ABSORPTION SPECTRA ANALYSIS

A method and apparatus is disclosed for resolving absorption spectra such as ultraviolet or visible spectra having individual peaks attributable to more than one component in a sample mixture. The invention exploits the observation that the peak wavelength varies according to the component concentrations, providing the basis for an initial estimate of these. A curve fitting exercise is performed for a range of possible concentrations encompassing the initial estimates so that the a theoretical spectrum having the closest match to that observed provides for a refined estimate of component concentrations.

DETECTION, CAPTURE AND QUATIFICATION OF BIOLOGICAL MOIETIES FROM UNPROCESSED BODILY FLUIDS USING NANOPLASMONIC PLATFORM

A nanoplasmonic platform can be used for the detection and quantification of multiple HIV subtypes in whole blood with localized surface plasmon resonance. Among other things, this nanoplasmonic platform provides a viable way to detection and quantification of viral load at a point of care with significantly less cost, time, and laboratory resources than existing methods of detection. Although an example of HIV detection in whole blood is provided, the nanoplasmonic platform is adaptable to detect other pathogens and infectious agents or macromolecules.

METHODS FOR OPTICALLY DETERMINING A CHARACTERISTIC OF A SUBSTANCE

Optical computing devices are disclosed. One exemplary optical computing device (300) includes an electromagnetic radiation source (308) configured to optically interact with a sample (306) and at least two integrated computational elements (302, 304). The at least two integrated computational elements are configured to produce optically interacted light (314), and at least one of the at least two integrated computational elements is configured to be disassociated with a characteristic of the sample. The optical computing device further includes a first detector (316) arranged to receive the optically interacted light from the at least two integrated computational elements and thereby generate a first signal corresponding to the characteristic of the sample.

IMAGE PROCESSING DEVICE, IMAGE PROCESSING METHOD, PROGRAM, AND STORAGE MEDIUM

In order to enable learning of identifiers for identifying the presence of a target cell in an image while a user performs cell-examination work, an image-feature-value calculation unit (18) extracts image feature values of images of cell-candidate regions. An NRBC identification unit (20) uses previously learned identifiers to identify, on the basis of the image feature values of the images of the cell-candidate regions, whether the target cell is depicted in the cell-candidate regions. It cases when it is identified that the target cell is depicted in a cell-candidate region, an identification-result display unit (26) displays the image of the cell-candidate region. Furthermore, in cases when it is identified that the target cell is depicted in the cell-candidate region, an identifier learning unit (34) performs, on the basis of a user input related to whether the target cell is depicted in the cell-candidate region, identifier learning in which the image feature value of the image of ...

OPTICAL PULSE GENERATING APPARATUS, TERAHERTZ SPECTROSCOPY APPARATUS, AND TOMOGRAPHY APPARATUS

An optical pulse generating apparatus that supplies pump light and probe light includes a light source and a modulation unit configured to modulate light emitted from the light source, thereby dividing the light into the pump light and the probe light. The modulation unit is configured such that a frequency for modulating the light is variable. The modulation unit changes a difference between a moment of the pump light incident on an object and a moment of the probe light incident on the object by changing the frequency.

SYSTEM AND METHOD OF DETECTING CONTAMINANTS

A system including a first container, wherein the first container includes a sample. The system includes a second container, wherein the second container comprises a reagent. Additionally, the system includes a test cell, wherein the test cell is configured to receive the sample and the reagent. Further, the reagent includes at least one of Griess reagent, sulfanilamide, or 1,5-diphenylcarbazide. Moreover, the test cell is situated in a chamber, wherein internal walls of the chamber are white.

METHOD AND DEVICE FOR ADJUSTING QUALITY DETERMINATION CONDITIONS FOR TEST BODY

A method for adjusting a condition for determining a quality of an inspection object comprises: acquiring measurement values for the structures of a plurality of inspection objects; determining whether each of the plurality of inspection objects is good or defective by comparing error values of the measurement values with respect to design values with a predetermined reference value; identifying one or more inspection objects in which determination error has occurred among the plurality of inspection objects; generating and outputting an inspection result graph including the number of inspection objects according to the error values, the reference value, and the number of the one or more inspection objects in which the determination error has occurred; updating the reference value according to a graphical input; and redetermining whether each of the plurality of inspection objects is good or defective by comparing the error values with the updated reference value.

Method of photocarrier radiometry of semiconductors

The present invention relates to metrologic methodologies and instrumentation, in particular laser-frequency domain infrared photocarrier radiometry (PCR), for contamination and defect mapping and measuring electronic properties in industrial Si wafers, devices and other semiconducting materials. In particular the invention relates to the measurement of carrier recombination lifetime, tau, carrier diffusivity, D, surface recombination velocities, S, carrier diffusion lengths, L, and carrier mobility, mu, as well as heavy metal contamination mapping, ion implantation mapping over a wide range of dose and energy, and determination of the concentration of mobile impurities in SiO2 layers on semiconductor substrates. The present invention provides a method and complete photocarrier radiometric apparatus comprising novel signal generation and analysis techniques (carrier-wave interferometry) as well as novel instrumental hardware configurations based on the physical principle of photocarrier ...

APPARATUS AND METHOD FOR GENERATING TOMOGRAPHY IMAGES

Provided is an apparatus and method for generating tomography images, the apparatus including a detection unit configured to modulate each of incident beams into at least two basic modulated incident lights on the basis of at least a basic modulation parameter and into a target modulated incident light on the basis of a target modulation parameter, and to detect at least two basic interference signals and a target interference signal of an object; and an imaging unit configured to analyze the at least two basic interference signals to output a set target modulation parameter, to process the target interference signal as a target image of the object, and to output the target image.

Method for producing high purity X-chromosome bearing and Y-chromosome bearing populations of spermatozoa

Isolated non-naturally occurring populations of spermatozoa (15) having high purity and technologies to differentiate spermatozoa (28) based on characteristics such as mass, volume, orientation, or emitted light including methods of analysis and apparatus such as beam shaping optics (30) and detectors (32).

BIOMETRIC IDENTIFICATION SYSTEMS AND ASSOCIATED DEVICES

The present disclosure provides techniques and apparatus for capturing an image of a person's retina fundus, identifying the person, accessing various electronic records (including health records) or accounts or devices associated with the person, determining the person's predisposition to certain diseases, and/or diagnosing health issues of the person. Some embodiments provide imaging apparatus having one or more imaging devices for capturing one or more images of a person's eye(s). Imaging apparatus described herein may include electronics for analyzing and/or exchanging captured image and/or health data with other devices. In accordance with various embodiments, imaging apparatus described herein may be alternatively or additionally configured for biometric identification and/or health status determination techniques, as described herein.

Method for detecting solid-liquid distribution in solid-liquid separation column of solid-liquid separation device and detection device

A method and a device, for detecting a solid-liquid distribution in a solid-liquid separation column of a freeze concentration device, that are used when a freeze concentration method is performed is suggested. The device for detecting the solid-liquid distribution in the solid-liquid separation column of a solid-liquid separation device includes a light irradiation means for irradiating the inside of the solid-liquid separation column of the freeze concentration device with visible light, a photographing means for picking up an image of the inside of the solid-liquid separation column irradiated with the visible light by the light irradiation means, a movement means for moving the photographing means in an up-and-down direction of the solid-liquid separation column, an image analysis means for analyzing a data piece of an image picked up by the photographing means and a determination means for determining a solid-liquid distribution state in the solid-liquid separation column based on ...

SEMICONDUCTOR DEVICE INSPECTION METHOD AND SEMICONDUCTOR DEVICE INSPECTION APPARATUS

A semiconductor device inspection method of inspecting a semiconductor device which is an inspection object includes: a step of inputting a stimulation signal to the semiconductor device; a step of acquiring a detection signal based on a reaction of the semiconductor device to which the stimulation signal has been input; a step of generating a first in-phase image and a first quadrature image including amplitude information and phase information in the detection signal based on the detection signal and a reference signal generated based on the stimulation signal; and a step of performing, a filtering process of reducing noise on at least one of the first in-phase image and the first quadrature image and then generating a first amplitude image based on the first in-phase image and the first quadrature image.

COMBINED PHOTOACOUSTIC AND ULTRASOUND IMAGING SYSTEM

The present disclosure provides for a system that is adapted to simultaneously display photoacoustic and ultrasound images of the same object. An image combiner can perform spatial and temporal interpolation of the two images before generating a combined image. The combined image is then displayed on a display such as an LCD or CRT. The system is able to use motion estimates obtained from the ultrasound data to enhance the photoacoustic image thereby increasing its apparent frame rate, registering consecutive frames in order to reduce artifacts. The system is capable of generating combined ultrasound and photoacoustic images which are registered spatially and temporally.

Многоканальный анализатор сигналов волоконно-оптических датчиков на основе волоконных брэгговских решеток

Полезная модель относится к области измерительной техники и может быть использована для измерения спектральных характеристик и показаний с волоконно-оптических датчиков, в частности в тепловой и ядерной энергетике, в химической и нефтегазовой, а также в критических узлах других отраслей промышленности.Техническим результатом настоящего технического решения является повышение точности определения относительного смещения спектра отражения брэгговской решетки, возможность определения абсолютной длины волны отражения ВБР, а также нечувствительность к спектральным потерям в линии и приемной части.Разработан анализатор сигналов, включающий перестраиваемый (на 80 нм) источник оптического излучения, средства передачи света, датчик на основе 8 линий волоконных брегговских решеток (ВБР), интерферометр и процессор. Брэгговские длины волн ВБР каждой линии различаются на постоянную величину, т.е. λ-λ=const. Средства передачи света обеспечивают направление света от источника излучения к ВБР-датчикам, а отраженное от ВБР-датчиков излучение на интерферометр, подключенный через фотоприемники к процессору, который управляет процессами перестройки источника переключением оптических переключателей в составе средств передачи света и детектора и обрабатывает сигналы с фотоприемников, сопоставляя их с калибровочными данными, выдает значение текущей длины волны отражения каждого из ВБР-датчиков в линии (линиях).Интегрально-оптическое исполнение элементов: источника, средств передачи света: ответвителя, делителя, спектрально-селективного ответвителя, коммутатора и интерферометра Маха-Цандера позволяет получить малогабаритный прибор с высокой вибростойкостью и температурной стабильностью. РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 192 705 U1 (51) МПК G01M 11/00 (2006.01) G01N 21/17 (2006.01) G01D 5/353 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ОПИСАНИЕ ПОЛЕЗНОЙ МОДЕЛИ К ПАТЕНТУ (52) СПК G01L 11/02 (2019.08); G01N 21/17 (2019.08); G01D 5/35329 (2019.08) (21)(22) Заявка: ...

Method for analysis of isotopes in bodily fluids

Biological fluid samples containing proteins (e.g., blood plasma or saliva) are prepared for isotopic analysis by precipitating the proteins while leaving the isotopic ratio unaffected. This precipitation can involve adding metal ions, salts, organic solvents, or organic polymers. The sample is then centrifuged to allow transfer of the supernatant for isotopic analysis, e.g. by tunable diode laser absorption spectrometry to obtain a quantitative measure of the 2 H and 18 O isotope levels in the water relative to reference standards.

Inspection Apparatus and Method

Ghost reflections in a catadioptric scatterometer objective are excluded from an angle-resolved spectrum measurement by using a partial pupil for illumination and for the measurement excluding the area of the pupil plane that has been illuminated. Ghost reflections are reflected back into same point in the pupil plane. The ghost reflections do not interfere with the signal in the non-illuminated area of the pupil plane. An illumination system provides a beam of electromagnetic radiation to illuminate a first area in an illumination pupil plane of the objective. The objective is arranged as to illuminate the substrate with the beam of electromagnetic radiation. The illumination pupil plane is the back projected image of the pupil plane of the objective and is also imaged into the measurement pupil plane at the back focal plane of the objective, via auxiliary optics. A detector is configured to measure an angle resolved spectrum arising from the illumination of the substrate, in a measurement area of the measurement pupil plane of the objective excluding an area corresponding to the first area.

Imaging apparatus and imaging method

An imaging apparatus includes changing unit for changing a positional relation of irradiation positions of a plurality of measuring beams to be radiated onto an object. The imaging apparatus includes scanning unit for scanning the plurality of measuring beams in the positional relation which has been changed by the changing unit, and acquiring unit for acquiring an optical coherence tomographic image of the object on the basis of the plurality of measuring beams.

Temperature dependent photoacoustic imaging

Methods and systems relating to temperature dependent photoacoustic imaging are provided.

Apparatus And Method For Non-Intrusive Assessment Of Gas In Packages

A method and apparatus are disclosed for assessment of a sealed package. Light is emitted from a narrow-band laser source towards said package from outside of said package. An absorption signal of said light scattered in said package is measured, wherein said absorption is caused by said at least one gas when said light is scattered and travels in said sealed package. Measuring is made outside of said package, whereby said assessment is non-intrusive with regard to said package. It is determined if a deviation exists from a predetermined, expected gas composition and/or concentration of said at least one gas within said sealed package based on said measured absorption signal. Thus sealing of said package for said gas is detected.

System and method for noninvasively monitoring conditions of a subject

A method and system are presented for use in determining one or more parameters of a subject. A region of interest of the subject is irradiated with acoustic tagging radiation, which comprises at least one acoustic tagging beam. At least a portion of the region of interest is irradiated with at least one electromagnetic beam of a predetermined frequency range. Electromagnetic radiation response of the at least portion of the region of interest is detected and measured data indicative thereof is generated. The detected response comprises electromagnetic radiation tagged by the acoustic radiation. This enables processing of the measured data indicative of the detected electromagnetic radiation response to determine at least one parameter of the subject in a region corresponding to the locations in the medium at which the electromagnetic radiation has been tagged by the acoustic radiation, and outputting data indicative of the at least one determined parameter.

Photoacoustic sensor and method for the production and use thereof

A photoacoustic sensor, containing a resonance body, which at least partially delimits a space for receiving molecules to be detected, and a device for detecting an oscillation of the resonance body, including a device for optically detecting the location of at least one partial surface of the resonance body. A method for the photoacoustic detection of molecules in the gas phase and to a method for producing an optically integrated photoacoustic sensor.

Acoustic wave measuring apparatus, acoustic wave imaging apparatus and method for controlling acoustic wave measuring apparatus

An acoustic wave measuring apparatus includes a light source for radiating a light having a wavelength component in wavelength areas, light filters arranged in a light path from the light source to a subject and each to shut off or transmit the light in one of the wavelength areas, a detector for detecting an acoustic wave generated by the radiation, a controller for generating conditions having different combinations of the wavelength components contained in the light, and a signal processor for calculating an optical absorption coefficient of the subject for the light in each wavelength area based on a pressure of the acoustic wave detected under each of the conditions and a strength of the radiated light for each wavelength area under conditions.

Imaging apparatus for diagnosis and control method thereof

An imaging apparatus for diagnosis is connected with a probe including a transmitting and receiving unit transmitting a light transmitted from a light source continuously to the inside of a body cavity and concurrently, receiving a reflected light continuously from the inside of the body cavity, and generates a tomographic image inside the body cavity based on the obtained reflected light by obtaining the reflected light from the transmitting and receiving unit while rotating the transmitting and receiving unit. The apparatus comprises: a mechanism for extracting intensity of the reflected light obtained by a phenomenon that the light transmitted to the transmitting and receiving unit is reflected at the transmitting and receiving unit; and a mechanism for judging whether or not the extracted intensity of each reflected light at each rotary angle of the transmitting and receiving unit lies in a range of a predetermined variation width.

Minimally invasive cytometry system with qcl inspection of single cells for cancer detection

This disclosure concerns a minimally invasive cytometry system including a handling system that presents single cells to at least one QCL laser source. The QCL laser source is configured to deliver light to a cell within the cells in order to induce vibrational bond absorption in one or more analytes within the cell. The cytometry system also includes a detection facility that detects the mid-infrared wavelength light transmitted by the cell and identifies the cell as either cancerous or non-cancerous.

Systems and Methods for Detection and Quantitation of Analytes Using an Oscillating Stimulus

Described systems and methods allow the detection of and determination of a concentration of a target analyte such as a biological cell, a virus, a polypeptide, a toxin, a pesticide, a drug, a drug residue, or a DNA strand, in a fluid sample. A variable stimulus, such as an oscillating magnetic field or a light beam of oscillating intensity, is applied to the sample, inducing variations in a position or shape of a constituent of the sample, or variations in a fluorescence of the sample. Such variations produce measurable variations in electric and/or optical properties of a sensor, variations which allow the determination of the concentration of the target analyte.

Subject information acquisition apparatus and subject information acquisition method

A subject information acquisition apparatus includes: an acoustic wave detector which detects an acoustic wave which is generated from a subject by irradiating light and outputs a detection signal; an amplifier which amplifies the detection signal which is output from the acoustic wave detector; a gain control unit which changes a gain of the amplifier as time elapses, according to a gain control table, in order to correct a drop in intensity of the acoustic wave caused by attenuation of fluence inside the subject; and a signal processing unit which obtains information inside the subject based on the signal amplified by the amplifier. Measurement under a plurality of measurement conditions, where at least fluence distribution inside the subject or a position of the acoustic wave detector differs, is possible, and the gain control unit changes the gain control table according to the measurement conditions.

Apparatus and method for irradiating a medium

A method for irradiating a medium with a wave which is designed to focus on a particular portion in the medium, the method includes: irradiating the medium with an electromagnetic wave which is scattered in the medium, and is not designed to focus on the particular portion in the medium; detecting a first signal caused by irradiating the medium with the electromagnetic waver; irradiating the medium with a reconstructed wave which is designed to focus on the particular portion in the medium; detecting a second signal caused by irradiating the medium with the reconstructed wave; and monitoring, based on the first and second signals, that the particular portion is irradiated by the reconstructed wave.

Methods and Systems for Real-Time Monitoring of Environments

Methods and systems for real-time monitoring of environments are disclosed. The methods include receiving a measurement by a sensor unit, and transmitting a signal to a monitoring station if the measurement is approximately between a lower and an upper threshold. Based on a number of signals received, the monitoring station will broadcast a signal indicating to stop transmission of measurements or to update the lower and the upper threshold and continue transmission of measurements. Transmission of measurements may occur during a given time slot.

Method and apparatus for medical imaging using near-infrared optical tomography and flourescence tomography combined with ultrasound

Methods and apparatus for medical imaging using diffusive optical tomography and fluorescent diffusive optical tomography are disclosed. In one embodiment, a method for medical imaging comprises, scanning a tissue volume with near-infrared light to obtain structural parameters, wherein the tissue volume includes a biological entity, scanning the tissue volume with near-infrared light to obtain optical and fluorescence measurements of the scanned volume, segmenting the scanned volume into a first region and a second region, and reconstructing an optical image and a fluorescence image of at least a portion of the scanned volume from the structural parameters and the optical and fluorescence measurements. In another embodiment an apparatus for medical imaging is disclosed.

Cavity enhanced laser based isotopic gas analyzer

Systems and methods for measuring the isotope ratio of one or more trace gases and/or components of gas mixtures such as different gas species present in a gas mixture. The system includes a resonant optical cavity having two or more mirrors and containing a gas, the cavity having a free spectral range that equals the difference between frequencies of two measured absorption lines of different gas species in the gas, or of two different isotopes, divided onto an integer number. The system includes a continuous-wave tunable laser optically coupled with the resonant optical cavity and a detector system for measuring an absorption of laser light by the gas in the cavity. The detector system includes a photo-detector to measure an intensity of the intra-cavity light, or both a photo-acoustic sensor to measure photo-acoustic waves generated in the cavity and a photo-detector to measure an intensity of the intra-cavity light.

SAMPLE ANALYZER

A sample analyzer comprising: a sample preparing section for preparing first and second measurement sample including reagent and sample; a first detector for detecting a predetermined component in the first measurement sample prepared by the sample preparing section; a second detector for detecting the predetermined component in the second measurement sample prepared by the sample preparing section; and a controller configured for performing operations, comprising: (a) controlling the first detector to detect the predetermined component in the first measurement sample prepared by the sample preparing section; (b) determining the reliability of the result detected by the first detector; (c) controlling the sample preparing section to prepare the second measurement sample from the same sample when the result has been determined to be unreliable; and (d) controlling the second detector to detect the predetermined component in the second measurement sample, is disclosed. 1. A sample analyzing method including:(a) executing a first measurement which includes preparing a first measurement sample by mixing a first part of a sample and a first reagent, providing the first measurement sample to a first detector, and obtaining a first result regarding a predetermined component in the first measurement sample;(b) executing a second measurement which includes preparing a second measurement sample by mixing a second part of the sample and a second reagent, providing the second measurement sample to a second detector, and obtaining a second result regarding the predetermined component in the second measurement sample;(c) determining reliability of the first result and the second result;(d) when the first and second results have been determined to be unreliable, executing a third measurement which includes preparing a third measurement sample by mixing a third part of the sample and a third reagent, providing the third measurement sample to the second detector, and obtaining a ...

CARRIER AND ADHESION AMOUNT MEASURING APPARATUS, AND MEASURING METHOD, PROGRAM, AND RECORDING MEDIUM OF THE SAME

A carrier includes attachment holes to which a catalyst attaches, and non-attachment holes to which the catalyst does not attach. An attachment quantity measurement device includes an electromagnetic wave output device that outputs a terahertz wave toward the carrier, an electromagnetic wave detector that detects the terahertz wave which has transmitted through the carrier, a reference value obtainer that obtains, based on a result detected by the electromagnetic wave detector, any one of an absorption rate, a group delay, and a dispersion of the terahertz wave in the non-attachment holes, and an attachment quantity obtainer that obtains, based on the result detected by the electromagnetic wave detector and the result obtained by the reference value obtainer, a weight or a density of the catalyst present in the attachment holes. 1. An attachment quantity measurement device comprising:an electromagnetic wave output device that outputs an electromagnetic wave to be measured having a frequency equal to or higher than 0.01 [THz] and equal to or lower than 100 [THz] toward a carrier, including an attachment hole to which a predetermined component attaches and a non-attachment hole to which the predetermined component does not attach;an electromagnetic wave detector that detects the electromagnetic wave to be measured which has transmitted through the carrier;a reference value obtainer configured to obtain a reference value, based on the electromagnetic wave detected by the electromagnetic wave detector, the reference value being one of an absorption rate, a group delay, and a dispersion of the electromagnetic wave to be measured in the non-attachment hole; andan attachment quantity obtainer configured to obtain, based on the electromagnetic wave detected by the electromagnetic wave detector and the reference value obtained by the reference value obtainer, at least one of a weight and a density of the predetermined component present in the attachment hole.2. The ...

DIRECT EXAMINATION OF BIOLOGICAL MATERIAL EX VIVO

The present invention relates to a method for the visual examination of biological material ex vivo and an apparatus for the sterical orientation of biological material which can be used in said method. 1. A method for visual examination of a biological material ex vivo , the method comprising:providing the biological material, wherein the biological material is vital biological material which is neither histologically nor optically cut;labeling the biological material;switching off of reflections at the surface of the biological material; andexamining the biological material by direct light microscopy.2. The method of claim 1 , further comprising moisturizing the biological material.3. The method of claim 2 , further comprising fixing the biological material.4. The method of claim 1 , wherein the switching off of reflections at the surface of the biological material comprises use of a transparent medium and a glass carrier claim 1 , wherein the transparent medium is essentially deposited without inclusion of air or gas between the biological material and the glass carrier and brought into direct contact with the glass carrier.5. The method of claim 1 , wherein the switching off of reflections at the surface of the biological material comprises use of polarized light in the examination by direct light microscopy (polarization microscopy).6. The method of claim 1 , wherein labeling the biological material comprises a staining reaction at the biological material.7. The method of claim 1 , wherein labeling the biological material comprises a specific immunoreaction at the biological material.8. The method of claim 7 , wherein the specific immunoreaction comprises:contacting the biological material with a primary antibody for binding the primary antibody to the biological material;removing the non-bound primary antibody from the biological material; anddetecting a specific binding of the primary antibody to the biological material.9. The method of claim 8 , wherein ...

System and Method for Nonlinear Optical Devices

Systems for enhancing the sensitivity of detecting an optical signal using nonlinear optics and method of performing the same. In one embodiment, a single-photon detection system includes an optical amplifier realized in a waveguide, and a photodetector coupled to an output of the optical amplifier. A light detection and ranging system includes the optical amplifier coupled to an optical source and one photodetector. In another embodiment, a photodetection system includes a plurality of optical frequency converters, coupled to an optical source, that sequentially convert a wavelength of photons of the optical source to a final wavelength, and a single-photon photodetector coupled to the optical frequency converters to detect single photons produced by the optical source. In another embodiment, an optical sensor includes an optical pump, and a transducer including an optical ring cavity coupled to the optical pump and configured to utilize optical four-wave mixing to detect an external stimulus. 1. An optical sensor , comprising:an optical pump; anda transducer comprising an optical ring cavity coupled to said optical pump and configured to utilize optical four-wave mixing to detect an external stimulus.2. The optical sensor as recited in further comprising a pump at an input end of an optical waveguide proximate said optical ring cavity and a photodetector coupled to an output end of said optical waveguide claim 1 , said pump being configured to induce an idler field in said optical ring cavity.3. The optical sensor as recited in wherein said four-wave mixing in said optical ring cavity is configured to generate a signal and an idler at equally spaced frequencies from said pump.4. The optical sensor as recited in wherein said photodetector is configured to measure a power of said idler.5. The optical sensor as recited in wherein said optical ring cavity is a nonlinear optical ring cavity.6. The optical sensor as recited in wherein said optical ring cavity is a ...

METHOD AND DEVICE FOR MEASURING SCATTERING-ABSORPTION BODY

Light irradiates one light incident position on the surface of a scattering-absorption body. The light that propagates through the interior of the scattering-absorption body is detected at one light detecting position on the surface of the scattering-absorption body. On the basis of a light detection signal, a temporal profile of the light intensity of the detected light is acquired, and on the basis of the temporal profile, an mean optical path length of the light in the interior of the scattering-absorption body and information relating to the amount of substance to be measured in a region to be measured are calculated. The information relating to the amount of substance to be measured is corrected on the basis of the mean optical path length, such that the longer the mean optical path length, the greater the amount of substance to be measured is. 1. A method for measuring a scattering-absorption body , which is a method for measuring , non-invasively , information relating to an amount of substance to be measured at a region to be measured of a scattering-absorption body that contains the region to be measured and an intervening tissue that is present between the region to be measured and a surface of the scattering-absorption body ,the method comprising:a light incidence step of causing light of a predetermined wavelength to be incident, through one light incident position that is set on the surface of the scattering-absorption body;a light detection step of obtaining a light detection signal by detecting the light of the predetermined wavelength that propagates through the interior of the scattering-absorption body, at one light detecting position that is set on the surface of the scattering-absorption body;a signal processing step of acquiring a temporal profile of light intensity of the detected light, on the basis of the light detection signal; anda calculation step of calculating, on the basis of the temporal profile, an mean optical path length of the ...

APPARATUS FOR DETERMINING OPTICAL DENSITY OF LIQUID SAMPLE AND OPTICAL WAVEGUIDE THEREOF

The present invention provides an optical waveguide, comprising: an input end for receiving a divergent beam; an output end for outputting an illuminating beam; a longitudinal cavity extending from the input end till the output end; a first pinhole located at a first predetermined distance from the input end within the said longitudinal cavity for receiving the divergent beam and for generating a fringe pattern, said first pinhole bifurcating the longitudinal cavity into a first and a second light propagating regions, the longitudinal cavity forming the first light propagating region being provided with a reflective coating on its internal surface to enable internal reflection of the divergent beam; and a second pinhole located at the output end for receiving the fringe pattern thus generated by the first pinhole and for outputting the illuminating beam corresponding to a central bright fringe contained in the said fringe pattern via the output end. 1. An optical waveguide , comprising:an input end for receiving a divergent beam;an output end for outputting an illuminating beam;a longitudinal cavity extending from the input end till the output end;a first pinhole located at a first predetermined distance from the input end within the said longitudinal cavity for receiving the divergent beam and for generating a fringe pattern, said first pinhole bifurcating the longitudinal cavity into a first and a second light propagating regions, the longitudinal cavity forming the first light propagating region being provided with a reflective coating on its internal surface to enable internal reflection of the divergent beam; anda second pinhole located at the output end for receiving the fringe pattern thus generated by the first pinhole and for outputting the illuminating beam corresponding to a central bright fringe contained in the said fringe pattern via the output end.2. The optical waveguide as claimed in claim 1 , wherein the first predetermined distance is selected ...

Device and Method for Monitoring and Quantifying Analytes

The present invention can be described as an apparatus and cartridge for detecting the presence of an analyte in a fluid. The invention can also be described as a method of detecting the presence of an analyte in a fluid using the apparatus and cartridge. The method comprises the steps of clamping a sensor cartridge into a cartridge receiver of the apparatus, providing fluid to a fluid flow-path of the cartridge, illuminating at least a portion of a sensor, and using a photodetector to detect a change in the optical property of the sensor, wherein the change is caused by the presence or absence of an analyte in the fluid. 1. An apparatus for detecting the presence of an analyte in a fluid in a cartridge , the apparatus comprising:a head assembly having a photodetector interface, the photodetector interface configured to cooperate with a sensor port of the cartridge to expose at least a portion of the photodetector interface to a sensor assembly of the sensor port;a tail assembly having an illumination interface, the illumination interface configured to cooperate with an illumination port of the cartridge to provide illumination to a portion of the sensor assembly;wherein the head assembly is in clamping relation to the tail assembly such that when a cartridge is disposed between the head and tail assemblies, the head and tail assemblies clamp the cartridge to form a fluidic seal between the illumination interface and illumination port and a fluidic seal between the photodetector interface, sensor assembly, and sensor port.2. The apparatus of claim 1 , further comprising a pump configured to move fluid through a cartridge disposed between the head and tail assemblies.3. The apparatus of claim 1 , further comprising a processor in electronic communication with the photodetector interface claim 1 , the processor configured to capture analyte detection information from the photodetector interface.4. The apparatus of claim 2 , further comprising a flow sensor claim 2 , ...

Chalcogenide-fibre, infrared evanescent wave sensor and process for producing same

The invention relates to a fibre sensor that enables the propagation of infrared light at at least one wavelength of 0.8 to 25 micrometres, the fibre successively comprising along its length a first infrared waveguide section ( 23 ), a second detection section ( 25 ) intended to come into contact with an external environment in order to detect infrared signatures interfering with the propagation of the evanescent waves propagating along the fibre ( 2 ), and a third infrared waveguide section ( 27 ). The invention is characterized in that, in the second fibre section ( 25 ) that has the detection role, the fibre ( 2 ) is constituted of a curved part, the radios of curvature of which is locally less than 2.3 millimetres.

Systems and methods for frequency-domain photoacoustic phased array imaging

Systems and methods of frequency-domain photoacoustic imaging are provided utilizing an ultrasonic phased array probe and intensity modulated optical excitation with coding to improve signal-to-noise ratio. Embodiments employ frequency-domain photoacoustic imaging methodologies such as the photoacoustic radar, coupled with a multi-element ultrasonic sensor array to deliver spatially-resolved correlation images of photoacoustic sources, which may be employed to image optical heterogeneities within tissue-like scattering media.

Electric field spectrum measurement device and object measurement device

Every depth of the measurement object measures energy structural information, refractive index, transmittance, reflectance other than property information of (as for the resolution several microns), e.g., space information at the same time. A spectrum measurement device receives a reference wave propagating in a reference path and a measurement wave propagating in a measurement path having a start point same as a start point of the reference path, and derives a spectrum of the measurement wave. The space information of the measuring object, energy structural information, refractive index, transmittance, a reflective index using spectrum measurement device are derived.

Acoustic wave detector and acoustic wave measurement apparatus

An acoustic wave detector includes: a transducer; and a light reflecting member which is positioned between the transducer and a subject surface that is irradiated with the light, and which reflects scattered light on the subject surface. The light reflecting member includes a first reflecting surface and a second reflecting surface positioned closer to the transducer than the first reflecting surface, and a distance between the first reflecting surface and the second reflecting surface is an odd multiple of a half wavelength of a predetermined wavelength included in an acoustic wave generated from the light reflecting member by the scattered light.

OPTICAL SENSOR

An optical sensor comprising a waveguide having a sensing layer which is molecularly imprinted such that it will receive and retain target entities to be sensed, the optical sensor further comprising a detection apparatus arranged to detect a change of an optical property of the waveguide which occurs when the target entities are received and retained in the sensing layer. 121-. (canceled)22. An optical sensor comprising a leaky mode waveguide having a sensing layer which is molecularly imprinted such that it will receive and retain target entities to be sensed , the optical sensor further comprising a detection apparatus arranged to detect a change of an optical property of the leaky mode waveguide which occurs when the target entities are received and retained in the sensing layer.23. An optical sensor as claimed in claim 22 , wherein the sensing layer comprises reception sites having shapes which are suitable for receiving the target entities.24. An optical sensor as claimed in claim 22 , wherein the sensing layer comprises reception sites having functional groups which are complementary to functional groups of the target entities.25. An optical sensor as claimed in claim 22 , wherein the sensing layer is porous.26. An optical sensor as claimed in claim 22 , wherein the optical property in which a change is detected is the refractive index.27. An optical sensor as claimed in claim 22 , wherein the target entities are ribonuclease.28. An optical sensor as claimed in claim 22 , wherein the target entities are inactive.29. An optical sensor as claimed in claim 22 , wherein the leaky mode waveguide includes a layer of material having a refractive index which is higher than the refractive index of the sensing layer.30. An optical sensor as claimed in claim 29 , wherein the layer of material is a metal layer.31. An optical sensor as claimed in claim 22 , wherein the sensing layer is a polymer layer.32. An optical sensor as claimed in claim 22 , wherein the sensor forms ...

Short light pulse generating device, terahertz wave generating device, camera, imaging device, and measuring device

A short light pulse generating device includes a light pulse generating part, a first pulse compressing part, a second pulse compressing part, and an amplifying part. The light pulse generating part is configured to generate light pulses, the light pulse generating part being a super luminescent diode. The first pulse compressing part is configured to perform pulse compression based on saturable absorption on the light pulses generated by the light pulse generating part. The second pulse compressing part is configured to perform pulse compression based on group velocity dispersion compensation on the light pulses that underwent the pulse compression by the first pulse compressing part. The amplifying part is provided between the first pulse compressing part and the second pulse compressing part, and configured to amplify the light pulses that underwent the pulse compression by the first pulse compressing part.

IMAGE INFORMATION OBTAINING APPARATUS AND CONTROL METHOD FOR SAME

An image information obtaining apparatus having: a light source; a transducer which detects an acoustic wave and converts the acoustic wave to an electrical signal; a signal processing unit which generates image data, using the electrical signal; and a memory unit which stores a reference acoustic signal produced by the transducer detecting an acoustic wave generated when light is irradiated from the light source onto a phantom having acoustic parameters and optical parameters substantially the same as an object and converting the acoustic wave to an electrical signal, wherein the transducer produces an object acoustic signal by converting the acoustic wave, generated when light is irradiated onto an object from the light source, to an electrical signal; and the signal processing unit subtracts the reference acoustic signal from the object acoustic signal and generates image data from the signal resulting from this subtraction. 1. An image information obtaining apparatus , comprising:a light source;a transducer which detects an acoustic wave and converts the acoustic wave to an electrical signal;a signal processing unit which generates image data, using the electrical signal;a memory unit which stores a reference acoustic signal produced by said transducer detecting an acoustic wave generated when a phantom having acoustic parameters and optical parameters substantially the same as an object is irradiated with light from said light source and converting the acoustic wave to an electrical signal, whereinsaid transducer produces an object acoustic signal by converting the acoustic wave, generated when an object is irradiated with light from said light source, to an electrical signal, andsaid signal processing unit subtracts the reference acoustic signal from the object acoustic signal and generates image data from the signal resulting from this subtraction.2. An image information obtaining apparatus , comprising:a light source;a transducer which detects an acoustic ...

DEVICE FOR DETECTING AN ANALYTE IN A BODILY FLUID

A device is proposed for detecting at least one analyte in a bodily fluid. The device comprises at least one test element with at least one two-dimensional evaluation region. The device furthermore comprises at least one spatially resolving optical detector having a plurality of pixels. The detector is designed to image at least part of the test element onto an image region. In the process, at least part of the evaluation region is imaged onto an evaluation image region. The detector is matched to the test element such that a predetermined minimum number of pixels is provided for each dimension within the evaluation image region. The pixels are arranged in a two-dimensional matrix arrangement. The matrix arrangement has pixel rows and pixel columns, wherein the pixel rows are arranged substantially parallel to a longitudinal direction of the evaluation region and/or of the evaluation image region. 1. A device for detecting at least one analyte in a bodily fluid , comprising:a test element having a two-dimensional evaluation region; anda spatially resolving optical detector having a plurality of pixels, the detector being configured to image at least part of the test element onto an image region and to image at least part of the evaluation region onto an evaluation image region; the detector is matched to the test element such that a predetermined minimum number of pixels is provided for each dimension within the evaluation image region;', 'the pixels are arranged in a two-dimensional matrix having pixel rows and pixel columns; and', 'the pixel rows are arranged substantially parallel to a longitudinal direction of at least one of the evaluation region or the evaluation image region., 'wherein2. The device as claimed in claim 1 , wherein the device is configured such that bodily fluid is transferred onto the test element for detecting the analyte.3. The device as claimed in claim 1 , further comprising a lancet element with a capillary configured to take up bodily ...

Chemical mapping using thermal microscopy at the micro and nano scales

A non-destructive method for chemical imaging with ˜1 nm to 10 μm spatial resolution (depending on the type of heat source) without sample preparation and in a non-contact manner. In one embodiment, a sample undergoes photo-thermal heating using an IR laser and the resulting increase in thermal emissions is measured with either an IR detector or a laser probe having a visible laser reflected from the sample. In another embodiment, the infrared laser is replaced with a focused electron or ion source while the thermal emission is collected in the same manner as with the infrared heating. The achievable spatial resolution of this embodiment is in the 1-50 nm range.

Optical constant measuring apparatus and method thereof

Disclosed is an optical constant measuring method which includes applying light to a sample including a target material; measuring a first optical signal from light reflected from the sample; grasping a structure of the sample based on the first optical signal; measuring a second optical signal from light penetrating the sample; grasping an overall optical property of the sample based on the second optical signal; and measuring an optical constant of the target material based on the measured structure and optical property of the sample.

OBJECT IDENTIFICATION DEVICE

An object identification device identifying an image region of an identification target includes an imaging unit receiving two polarization lights and imaging respective polarization images, a brightness calculation unit dividing the two polarization images into processing regions and calculating a brightness sum value between the two polarizations images for each processing region, a differential polarization degree calculation unit calculating a differential polarization degree for each processing region, a selecting condition determination unit determining whether the differential polarization degree satisfies a predetermined selecting condition, and an object identification processing unit specifying the processing region based on the differential polarization degree or the brightness sum value depending on whether the predetermined selecting condition is satisfied and identifying plural processing regions that are specified as the processing regions as the image region of the identification target. 1. An object identification device identifying an image region of an identification target in an imaged image imaging the identification target in an imaging region , the object identification device comprising:an imaging unit that receives two polarization lights included in reflected light from an object existing in the imaging region and having respective polarization directions different from each other, and that images respective polarization images;a brightness calculation unit that divides two of the polarization images imaged by the imaging unit into respective predetermined processing regions, and that calculates a brightness sum value between the two polarization images for each processing region;a differential polarization degree calculation unit that calculates a differential polarization degree for each of the processing regions, the differential polarization degree indicating a ratio of a brightness difference value between the two polarizations images ...

Method And Device For Assay Determination

A device and method for determining the assay result is disclosed. The device includes a photoelectric detection circuit and a processor, and an optical detection device which is set with a detection zone and a blank zone for measuring assay results, and the photoelectric detection circuit detects the light-reflection intensity signal, and feeds back the detected information to the processor, and the processor is preset with a threshold value changing with time, and determined value processed by the processor is compared with the preset threshold value to obtain the result of assay. The method for determining the assay result display the result when confirmed determined value is bigger than the preset threshold value or can not reach preset threshold value within a fixed time or detected signal can not be determined, wherein the threshold value changes with the time. The device and method for determining the assay result work more efficiently, measure more accurately and cost less than the prior art. 1. A device for assay determination , comprising:a photoelectric detection circuit;a processor; andan optical detection device for measuring assay signals, provided with a detection zone and a blank zone, wherein the photoelectric detection circuit detects light-reflection intensity signals from the detection zone and the blank zone, and feeds back detected information to the processor;wherein the processor comprises a time controlling module, a threshold modification module and a datum comparison module which are connected to each other, the time controlling module is connected with the threshold modification module and the photoelectric detection circuit separately, and the threshold modification module and the photoelectric detection circuit are connected with the datum comparison module at the same time, the threshold modification module modifies threshold value according to signals from the time controlling module which is then sent to the datum comparison module, ...

Process and Installation for Inspection and/or Sorting Combining Surface Analysis and Volume Analysis

Automatic process and installation for inspecting and/or sorting objects or articles belonging to at least two different categories, and made to advance approximately in a single layer, for example on a conveyor belt or a similar transport support. The process includes subjecting the advancing flow of objects or articles to at least two different types of contactless analysis by radiation, whose results are used in a combined manner for each object or article to perform a discrimination among these objects or articles and/or an evaluation of at least one characteristic of the latter, the analyses including at least one surface analysis process able to determine the physical and/or chemical composition of the outer layer of an object or article exposed to the radiation used in this process, and at least one volume analysis process able to determine the equivalent thickness of material of the same object or article.

OPTICAL PULSE GENERATING APPARATUS, TERAHERTZ SPECTROSCOPY APPARATUS, AND TOMOGRAPHY APPARATUS

An optical pulse generating apparatus that supplies pump light and probe light includes a light source and a modulation unit configured to modulate light emitted from the light source, thereby dividing the light into the pump light and the probe light. The modulation unit is configured such that a frequency for modulating the light is variable. The modulation unit changes a difference between a moment of the pump light incident on an object and a moment of the probe light incident on the object by changing the frequency. 1. An optical pulse generating apparatus that supplies pump light and probe light , the optical pulse generating apparatus comprising:a light source; anda modulation unit configured to modulate light emitted from the light source, thereby dividing the light into the pump light and the probe light,wherein the modulation unit is configured such that a frequency for modulating the light is variable, andwherein the modulation unit changes a difference between a moment of the pump light incident on an object and a moment of the probe light incident on the object by changing the frequency.2. The optical pulse generating apparatus according to claim 1 ,wherein the modulation unit includes an electro-optical modulator or acousto-optic modulator, andwherein the modulation unit divides the light into the pump light and the probe light by performing binary modulation on the electro-optical modulator or the acousto-optic modulator.3. The optical pulse generating apparatus according to claim 2 ,wherein the modulation unit includes a power supply,wherein the electro-optical modulator is a Mach-Zehnder modulator, andwherein the modulation unit divides the light into the pump light and the probe light by performing on-off keying on the electro-optical modulator using the power supply.4. The optical pulse generating apparatus according to claim 2 ,wherein the modulation unit includes a digital signal source that turns on and off a radio frequency signal to be ...

Method for determining the active doping concentration of a doped semiconductor region

A method and system for optically determining a substantially fully activated doping profile are disclosed. The substantially fully activated doping profile is characterized by a set of physical parameters. In one aspect, the method includes obtaining a sample comprising a fully activated doping profile and a reference, and obtaining photomodulated reflectance (PMOR) offset curve measurement data and DC reflectance measurement data for the sample including the fully activated doping profile and for the reference. The method also includes determining values for the set of physical parameters of the doping profile based on both the photomodulated reflectance offset curve measurements and the DC reflectance measurements.

METHOD AND APPARATUS FOR DEGASSING A LIQUID AND ANALYTICAL DEVICE HAVING THE APPARATUS

A method for degassing a liquid by means of a piston pump unit having a receiving chamber serving for accommodating the liquid to be degassed and connected with at least one supply line and at least one drain line, and a piston seated in the receiving chamber for performing stroke movements and liquid sealing the receiving chamber on one end. The following steps are included: drawing liquid via the supply line into the receiving chamber by performing a first stroke movement of the piston in the case of blocked drain line and open supply line; producing a negative pressure in the receiving chamber by continuing the first stroke movement of the piston in the case of blocked supply line and blocked drain line; and opening the drain line and removing a gas phase present in the receiving chamber from the receiving chamber via the drain line by performing a second stroke movement of the piston directed counter to the first stroke movement in the case of an opened drain line and blocked supply line. 115-. (canceled)16. A method for degassing a liquid by means of a piston pump unit having a receiving chamber serving for accommodating the liquid to be degassed and connected with at least one supply line and at least one drain line , and a piston seated in the receiving chamber for performing stroke movements and liquid sealing the receiving chamber on one end , the method comprises the steps of:drawing liquid via the supply line into the receiving chamber by performing a first stroke movement of the piston in the case of a blocked drain line and open supply line;producing a negative pressure in the receiving chamber by continuing the first stroke movement of the piston in the case of blocked supply line and blocked drain line; andopening the drain line and removing a gas phase present in the receiving chamber from the receiving chamber via the drain line by performing a second stroke movement of the piston directed counter to the first stroke movement, in the case of an ...

PHOTOACOUSTIC IMAGING APPARATUS AND CONTROL METHOD THEREOF

A photoacoustic imaging apparatus is used that comprises a light source capable of irradiating light onto an object from a plurality of directions, a detector that detects acoustic waves generated by the object irradiated with light, a calculator that calculates object information from detected acoustic waves, and a generator that generates image data from the object information. The calculator calculates a plurality of object information pieces corresponding to irradiation in respective directions on the basis of acoustic waves at a time of irradiation of light at dissimilar timings from the plurality of directions. The generator selects, for each region and according to a predetermined criterion, image data of increased contrast in a case where a plurality of image data items on the object are generated on the basis of the plurality of object information pieces, and generates image data by combining the image data selected in each region. 110.-. (canceled)11. An object information obtaining apparatus comprising:a light source configured to irradiate an object with light from a first direction and a second direction different from the first direction;a detector configured to detect an acoustic wave generated by the object irradiated with light;a calculator configured to obtain object information on the basis of acoustic waves detected by said detector; anda generator configured to generate image data of the object on the basis of the object information,wherein said calculator is configured to obtain first object information on the basis of the acoustic wave generated upon irradiation of the object with light from the first direction at a first timing, and to obtain second object information on the basis of the acoustic wave generated upon irradiation of the object with light from the second direction at a second timing different from the first timing, andwherein said generator is configured to generate image data by combining the first object information and the ...

PHOTOACOUSTIC WAVE MEASURING APPARATUS

A photoacoustic wave measuring apparatus, having: a probe including a plurality of devices which detect an acoustic wave generated by irradiating light onto an object; and a signal processor which acquires information about the object on the basis of an acoustic wave received by the devices, wherein the light is irradiated onto the object from the probe side; the probe includes: bright-field devices having a view angle covering a bright-field illumination area, which is an area where the light is irradiated, on the probe-side surface of the object; and dark-field devices having a field of view which does not cover the bright-field illumination area; and the signal processor uses an acoustic wave received by the dark-field devices when acquiring information about the object on the basis of a acoustic wave received before a predetermined time period is elapsed since the irradiation of light onto the object. 1. A photoacoustic wave measuring apparatus , comprising:a probe including a plurality of devices which receive an acoustic wave generated by irradiating an object with light; anda signal processor which acquires information about the object on the basis of an acoustic wave received by said devices, whereinthe light object is irradiated with the light from the probe side; bright-field devices having a view angle covering a bright-field illumination area, which is an area where the light is irradiated, on the probe-side surface of the object; and', 'dark-field devices having a field of view which does not cover the bright-field illumination area; and', 'said signal processor uses an acoustic wave received by said dark-field devices when acquiring information about the object on the basis of an acoustic wave received before a predetermined time period is elapsed since the irradiation the object with light., 'said devices of said probe include2. The photoacoustic wave measuring apparatus according to claim 1 , wherein said signal processor uses an acoustic wave ...

Changed optical path measuring device for component concentration of water and measuring method thereof

Measuring device of the present invention includes a plurality of measuring sites for generating a plurality of optical paths and various dilutions. The range for concentration measurement and the measurement accuracy are enhanced due to the plurality of optical path length, and the interference on the measurement ranges and results caused by the concentration or the turbidity of suspended solid is reduced and removed by water sample dilution, and thus the characteristic wavelengths of the components in the water are measured. Next, the information of spectrum database is used to determine the ingredients which may exist in the water (qualitative analysis), and UV-VIS-NIR absorbance spectrum analysis is used to obtain the concentration of the respective ingredients in the water at the same time (quantitative analysis).

Photoacoustic method for oxygen sensing

A method for photoacoustically sensing oxygen in a gaseous sample is disclosed, together with an apparatus for practicing the present method. Efficient and cost-effective oxygen sensing is provided by the use of a light source in the form of a light-emitting diode, which can be selected to correspond with the absorption spectra exhibited by oxygen in a gaseous sample. Filtering can be employed in order to control and narrow the wavelength of light emitted by the light source. An apparatus is disclosed which facilitates practice of the present method, including an arrangement by which ambient noise and vibration can be canceled.

QUALITATIVE CRYSTAL DEFECT EVALUATION METHOD

A process is provided for evaluating oxygen precipitates in a single crystal silicon sample. The process comprises (a) annealing the single crystal silicon sample at a temperature sufficient to selectively grow as-grown oxygen precipitates having a size of about 25 nm or more and selectively dissolve as-grown oxygen precipitates having a size of about 25 nm or less; (b) cooling the single crystal silicon sample at a cooling rate sufficient to inhibit the nucleation of oxygen precipitates having a size of about 25 nm or less; (c) coating a surface of the single crystal silicon sample with a composition containing a metal capable of decorating oxygen precipitates; and (d) annealing the coated single crystal silicon sample at a temperature, for a duration, and in an atmosphere sufficient to decorate the oxygen precipitates in the single crystal silicon sample. 1. A process for evaluating oxygen precipitates in a single crystal silicon sample , the process comprising:(a) annealing the single crystal silicon sample at a temperature sufficient to selectively grow as-grown oxygen precipitates having a size of about 25 nm or more and selectively dissolve as-grown oxygen precipitates having a size of about 25 nm or less;{'b': '25', '(b) cooling the single crystal silicon sample at a cooling rate sufficient to inhibit the nucleation of oxygen precipitates having a size of about nm or less;'}(c) coating a surface of the single crystal silicon sample with a composition containing a metal capable of decorating oxygen precipitates; and(d) annealing the coated single crystal silicon sample at a temperature, for a duration, and in an atmosphere sufficient to decorate the oxygen precipitates in the single crystal silicon sample.2. The process as set forth in wherein the single crystal silicon sample comprises a silicon wafer sliced from a single crystal silicon ingot claim 1 , grown by the Czochralski method.3. The process as set forth in wherein the single crystal silicon sample ...

METHOD FOR DETERMINING SATURATED ABSORPTION LINES AND LASER FREQUENCY STABILIZING DEVICE

A method for determining saturated absorption lines includes defining first and second threshold values based on an output value of a light output signal. The first and second threshold values are in a magnitude relationship. An output value of a second-order differential signal of the light output signal is compared with the first and second threshold values. A determination is made as to whether the second-order differential signal following a change in a resonator length has an output waveform that displays a behavior in which the output waveform changes from less than the second threshold value to be equal to or greater than the first threshold value, and then changes to be less than the second threshold value. Based on a result of the determination by the waveform determination, a determination is made as to whether the output waveform of the second-order differential signal is the saturated absorption line. 1. A method for determining saturated absorption lines for a laser frequency stabilizing device , wherein a resonator length is changed and an oscillation frequency of laser light is stabilized to a specific saturated absorption line based on a saturated absorption line in a light output signal obtained by shining laser light on an absorption cell , the method comprising:defining a first threshold value and a second threshold value based on an output value of the light output signal, the first threshold value and the second threshold value being in a magnitude relationship;comparing an output value of a second-order differential signal of the light output signal with the first threshold value and the second threshold value, then determining whether the second-order differential signal following a change in the resonator length has an output waveform displaying a behavior in which the output waveform changes from less than the second threshold value to be equal to or greater than the first threshold value, and then changes to be less than the second ...

QUANTIFICATION OF OPTICAL ABSORPTION COEFFICIENTS USING ACOUSTIC SPECTRA IN PHOTOACOUSTIC TOMOGRAPHY

Accurately quantifying optical absorption coefficient using acoustic spectra of photoacoustic signals. Optical absorption is closely associated with many physiological parameters, such as the concentration and oxygen saturation of hemoglobin, and it can be used to quantify the concentrations of non-fluorescent molecules. A sample is illuminated by, for example, a pulsed laser and following the absorption of optical energy, a photoacoustic pressure is generated via thermo-elastic expansion. The acoustic waves then propagate and are detected by a transducer. The optical absorption coefficient of the sample is quantified from spectra of the measured photoacoustic signals. Factors, such as system bandwidth and acoustic attenuation, may affect the quantification but are canceled by dividing the acoustic spectra measured at multiple optical wavelengths. 1. A method of determining an optical absorption coefficient of an object , said method comprising:focusing a first light pulse emitted by a light source into a volume of the object, wherein the first light pulse has a first wavelength;detecting a first photoacoustic spectrum using an acoustic transducer, wherein the first acoustic spectrum is emitted by the object in response to receiving the first light pulse;focusing a second light pulse emitted by the light source into the volume of the object, wherein the second light pulse has a second wavelength;detecting a second acoustic spectrum using an acoustic transducer, wherein the second acoustic spectrum is emitted by the object in response to receiving the second light pulse; anddetermining the absorption coefficient of the volume of the object as a function of the first acoustic spectrum and the second acoustic spectrum.2. The method of wherein detecting the first acoustic spectrum comprises receiving at the acoustic transducer a first acoustic wave emitted by the object in response to receiving the first light pulse and performing a Fourier transformation on the ...

Method for measuring the area of a sample disposed within an analysis chamber

A method for determining the area of an analysis chamber covered by a biologic fluid sample quiescently residing within the chamber is provided. The chamber has a first panel with an interior surface, and a second panel with an interior surface, both of which panels are transparent. The method includes the steps of: a) illuminating the sample residing within the analysis chamber at one or more wavelengths operable to highlight interfaces between the sample and air, and to highlight a constituent within the sample; b) imaging the sample along the one or more wavelengths, and producing image signals representative of the interaction of the one or more wavelengths with the sample; c) determining a location of at least one interface between the sample and air, using the image signals; d) determining a location of one or more constituents within the sample relative to the at least one sample-air interface using the image signals; and e) determining an area of the chamber containing the sample, using the location of the one or more constituents and the at least one sample-air interface.

METHOD AND DEVICE FOR DETECTING TRACE AMOUNTS OF MANY GASES

The photoacoustic device for measuring the quantity of at least one gas. The Helmholtz-type esonant container comprises at least two tubes closed at their ends and linked together, close to each of their respective ends, by capillary tubes of diameter lower than the diameter of the parallel tubes. Each of the two radiant laser energy sources is physically separated and adapted to supply an excitation energy to the gas in the container at a different emission wavelength. The modulation means modulates the excitation energy supplied by each laser energy source with a modulation frequency corresponding to the acoustic resonance frequency of the container. At least one acoustoelectric transducer disposed on one of the tubes detects the produced acoustic signals produced and supplies an electric signal representative of the gas concentration in the container. 114-. (canceled)15. A photoacoustic device for measuring the quantity of at least one gas , comprising:a Helmholtz-type resonant container comprising at least two parallel tubes closed at their ends and linked together, close to their respective ends, by capillary tubes of a diameter less than the diameter of the parallel tubes;a gas introduction means in the resonant container;at least two radiant laser energy sources, each physically separated and adapted to supply an excitation energy to the gas contained in the container at a different emission wavelength, each corresponding to a maximum absorption wavelength locally for each gas, each laser energy source being positioned opposite a window closing an end of a parallel tube,a modulator for modulating the excitation energy supplied by each laser energy source with a modulation frequency corresponding to an acoustic resonance frequency of the resonant container; andat least one acoustoelectric transducer, disposed on one of the parallel tubes to detect acoustic signals produced therein and to supply an electric signal representative of the gas concentration in the ...

Photoacoustic measuring device and method

The present invention provides a photoacoustic measuring device and a method by which the presence of an object can be easily identifyied in a relatively short time in photoacoustic measurement while holding an object by a holding plate. The photoacoustic measuring device has a irradiating unit with which the object is irradiated with light, a holding unit holding the object by the holding plate, a detecting unit detecting the photoacoustic wave generated by irradiating light and an analyzing unit analyzing photoacoustic signal of the photoacoustic wave. The analyzing unit analyzes a photoacoustic signal to acquire information concerning change of a signal intensity of a component of the photoacoustic signal of produced in an interface between the detecting unit and the holding plate and an interface between the holding plate and the object, to identify the presence of the object.

DEVICE FOR TESTING AN OPTIC

A device for testing an optic which is mountable thereon and has a central axis extending in the longitudinal direction thereof, comprising a test image, a test image table for supporting the test image, a light source for lighting the test image via the optic mountable thereon, an attaching device for mounting the optic mountable thereon, detection means placed on the attaching means for detecting the lighted test image, first guide means and second guide means co-acting with the first guide means and extending in longitudinal direction thereof for the purpose of positioning the test image table along a substantially straight line relative to the attaching device, and a signal processing device for receiving, storing and comparing detection values of the lighted test image detected by the detection means to threshold values therefor specific to the optic and prestored in a database, whereby the optic can be tested quickly and without personal influences, with a reliable test result. 2120260. A device () as claimed in claim 1 , wherein the identification elements () comprise a barcode etched into the optic () and wherein the read elements () comprise a barcode scanner.31113502060. A device () as claimed in claim 1 , wherein the servomotor () is adapted to drive a displacement of the attaching device () relative to the test image () subject to identification elements () detected by the read elements ().415059. A device () as claimed in claim 1 , wherein the test image () is mounted on a concavely formed surface of a spherical surface ().515059. A device () as claimed in claim 4 , wherein the test image () is provided with a pattern which comprises information distributed concentrically over the concavely formed surface relative to the centre of the spherical surface ().6150. A device () as claimed in claim 1 , wherein the test image () comprises a grid and/or a pattern of markers.71110050100120212. A device () as claimed in claim 4 , wherein the device () comprises a ...

APPARATUS FOR PRODUCING HIGH PURITY X-CHROMOSOME BEARING AND Y-CHROMOSOME BEARING POPULATIONS OF SPERMATOZOA

Isolated non-naturally occurring populations of spermatozoa () having high purity and technologies to differentiate spermatozoa () based on characteristics such as mass, volume, orientation, or emitted light including methods of analysis and apparatus such as beam shaping optics () and detectors ().

OPTICAL SENSOR AND IMAGE FORMING APPARATUS

An optical sensor is disclosed. The optical sensor includes a light source in which a semiconductor laser having multiple light-emitting units is sealed with one resin member; a light source driving unit which causes the multiple light-emitting units to emit light; and at least one photodetector which detects a light amount of a light which is emitted from the multiple light-emitting units and is reflected from a subject. 1. An optical sensor , comprising:a light source in which a semiconductor laser having multiple light-emitting units is sealed with one resin member;a light source driving unit which causes the multiple light-emitting units to emit light; andat least one photodetector which detects a light amount of a light which is emitted from the multiple light-emitting units and is reflected from a subject.2. The optical sensor as claimed in claim 1 , wherein the light source driving unit temporally changes a magnitude of a drive current which is supplied to the semiconductor laser to temporally change a wavelength of a light emitted from the semiconductor laser.3. The optical sensor as claimed in claim 1 , wherein the at least one photodetector includes a first photodetector and a second photodetector;the first photodetector is arranged on an optical path of a light which is specularly reflected from the subject;the second photodetector is arranged on an optical path of a light which is diffuse reflected from the subject within an incident face in the subject;a light which is emitted from the light source is a linearly polarized light in a first polarizing direction; andthe optical sensor further includes an optical element which is arranged on an optical path of a diffuse reflected light which moves toward the second photodetector and which transmits a linearly polarized light component in a second polarizing direction which is orthogonal to the first polarizing direction.4. The optical sensor as claimed in claim 3 , wherein the first photodetector configures ...

MULTICHANNEL ANALYTICAL INSTRUMENTS FOR USE WITH SPECIMEN HOLDERS

An analytical instrument may have multiple distinct channels. Such may include one or more illumination sources and sensors. Illumination may be delivered to specific locations of a specimen holder, and returned illumination may be delivered to specific locations of a sensor array. Illumination may first pass a specimen, and a mirror or reflector may then return the illumination past the specimen. Optical splitters may be employed to couple pairs of fiber optics proximate a specimen holder. Such channels may further include a plurality of illumination sources positioned on one side of a specimen holder and a plurality of sensors on the other side. The plurality of sensor may capture image of a specimen and a spectrophotometer may concurrently scan the specimen. A plurality of specimens may be imaged and scanned in a single pass of a plurality of passes. Spherical or ball lenses may be placed in an optical path of the illumination to achieve a desired illumination pattern. 1. A multi-channel analytical instrument , comprising:at least one illumination source disposed on a first side of a specimen receiver having a plurality of wells, the at least one illumination source operable to emit electromagnetic energy through the plurality of wells;at least one sensor disposed on a second side of the specimen receiver, the at least one sensor responsive to electromagnetic energy received from the plurality of wells to produce a signal indicative of at least one characteristic of the electromagnetic energy;a plurality of first optical fibers coupled to the at least one illumination source;a plurality of second optical fibers coupled to the at least one sensor;a plurality of first ball lenses each positioned proximate a respective one of a plurality of positions disposed on the first side of the specimen receiver and spaced from one another along a first dimension of the specimen receiver;a plurality of second ball lenses each positioned proximate a respective one of a ...

Device for photometric analysis of a liquid sample and sample carrier therefor

The invention relates to a device for the analysis of a liquid sample by way of light, comprising a transparent sample carrier, a movable upper mirror, which can be moved between a closed position, in which the mirror encloses a measurement space between itself and the sample carrier, and an open position, in which the sample carrier can be accessed so as to apply a sample, and a beam path, which guides incident measurement light between a light entrance into the measurement space and a light exit out of the measurement space from the sample carrier to the upper mirror reflecting the light. The beam path guides measurement light at an oblique angle of incidence through the sample carrier to the upper mirror.

Magnetic particle based biosensor

A biosensor system and method of its use for detecting particles on the surface of an integrated circuit is disclosed. The system can include a light source and a plurality of optical sensors formed on an integrate circuit. The particles can be positioned the surface of the integrated circuit whereby the particles can cast a shadow or shadows that reduces the amount of light transmitted from the light source to the optical sensors. The surface of the integrated circuit can include one or more optical sensing areas whereby the presence of one or more particles may significantly or measurably reduce the amount of light incident on one or more optical sensor.

TARGET SUBSTANCE DETECTING APPARATUS, AND TARGET SUBSTANCE DETECTING METHOD

A target substance detecting apparatus includes a photonic crystal biosensor configured to include a photonic crystal, which has a reflection surface including concave portions and convex portions formed regularly on its surface, covered by a metal film, and reflecting light irradiated to the reflection surface; an optical detecting unit configured to irradiate parallel light to the reflection surface, and to detect reflected light of the parallel light reflected on the reflection surface; and a processing unit configured to obtain a wavelength at an extreme value of the reflected light detected by the optical detecting unit, and to detect at least whether the target substance is present or not based upon a shift of the obtained wavelength at the extreme value. 1. A target substance detecting apparatus comprising:a target substance trapping unit configured to include a structure, which has a reflection surface including concave portions and convex portions formed regularly on its surface, covered by a metal film, and trapping a target substance, the structure reflecting light irradiated to the reflection surface;an optical detecting unit configured to irradiate parallel light to the reflection surface, and to detect reflected light of the parallel light reflected on the reflection surface; anda processing unit configured to obtain a wavelength at an extreme value of the reflected light detected by the optical detecting unit, and to detect at least whether the target substance is present or not based upon a shift of the obtained wavelength at the extreme value.2. The target substance detecting apparatus according to claim 1 , whereinthe target substance trapping unit includes a target substance trapping substance that is fixed on the reflection surface for trapping the target substance.3. The target substance detecting apparatus according to claim 1 , whereinin the target substance trapping unit, the reflection surface on which a target substance of the same type as ...

METHOD AND SYSTEM FOR REPLACING THE WATER COOLED LASER IN A MICROPLATE READER

The present invention relates to a method and system for repairing and refurbishing a microplate reader of the Flipr type which has a water cooled argon laser light source. The old laser is removed and replaced with a high power (300 to 500 mW) air cooled solid state laser as a replacement place on its own support and focused and wired to replace the old laser. The new product operates at lower power consumption yet provides accurate measurements. 1. A method for repairing a fluorescence microplate reader having a water cooled laser light source of about 3 watts that has been removed from the reader comprising:a) selecting an air cooled laser having a wattage of between about 300 and 500 mW, having a total lumen output sufficient to produce a replacement lumen output, the air cooled laser mounted in a rigid support and provide light to the microplate reader;b) providing that the light output of the air cooled laser is at a desired wavelength;c) positioning the support such that the light from the air cooled laser shines on the bottom of a microplate positioned in the reader; andd) connecting the air cooled laser to the reader such that they operate in place of the water cooled laser light.2. A method according to wherein the air cooled laser emits light in a wavelength from about 425 to about 510 nanometers.3. A method according to wherein the LED's emit a maximum light out at a wavelength of about 488 nanometers.4. A system for replacing a water cooled laser in a fluorescence microplate reader comprising:a) An air cooled laser having a power of about 300 to 500 mW mounted in fixed relationship having a lumen output sufficient to produce a replacement lumen output;b) an optional filter for changing the wavelength of the LED lights to a desired wavelength where the wavelength of the air cooled laser is not originally a desired wavelength;c) a support for adjustably positioning the air cooled laser and optionally the filter in the reader such that when placed in the ...

Imaging Apparatus

An apparatus for measuring oil droplets and other bodies in a liquid, the apparatus comprising a body having an imaging device mounted therein, said body having a measurement window adjacent a measuring region through which an image of a fluid within the measurement region may be viewed by the imaging device, wherein a light source is provided for illuminating said measurement region, said light source being directed towards the imaging device by a light directing means, the apparatus including an ultrasonic transducer mechanically coupled to the measurement window for removing fouling from the measurement window and for creating cavitation within said measurement region, wherein said light directing means is located in or adjacent said measurement region to be exposed to said cavitation created by the ultrasonic transducer to remove fouling from said light directing means. 1. An apparatus for measuring oil droplets and other bodies in a liquid , the apparatus comprising a body having an imaging device mounted therein , said body having a measurement window adjacent a measuring region through which an image of a fluid within the measurement region may be viewed by the imaging device , wherein a light source is provided for illuminating said measurement region , said light source being directed towards the imaging device by a light directing means , the apparatus including an ultrasonic transducer mechanically coupled to the measurement window for removing fouling from the measurement window and for creating cavitation within said measurement region , wherein said light directing means is located in or adjacent said measurement region to be exposed to said cavitation created by the ultrasonic transducer to remove fouling from said light directing means.2. An apparatus as claimed in claim 1 , wherein said light directing means comprises a window through which light from the light source is transmitted claim 1 , a light guide through which said light is transmitted ...

WAVEGUIDE STRUCTURE FOR MID-IR MULTIWAVELENGTH CONCATENATED DISTRIBUTED-FEEDBACK LASER WITH AN ACTIVE CORE MADE OF CASCADED STAGES

Concatenated distributed feedback lasers having novel waveguides are disclosed. The waveguides allow for coupling of the laser beam between active and passive waveguide structures and improved device design and output efficiency. Methods of making along with methods of using such devices are also disclosed. 1. A waveguide structure comprising:a. an active semiconductor optical waveguide made of an optical gain material;b. a bridge; andc. a passive optical waveguide; wherein the bridge is spatially located between the active waveguide and passive waveguide and wherein the active waveguide, bridge, and passive waveguide are not physically connected via an optical waveguide material.2. The waveguide structure of claim 1 , wherein the bridge comprises a periodic structure that selectively allows certain wavelengths of light to couple to the passive optical waveguide.3. The waveguide structure of claim 1 , wherein the active waveguide claim 1 , bridge claim 1 , and passive waveguide comprise GaInAs or GaAlInAs.4. The waveguide structure of claim 1 , wherein the active waveguide and bridge or the bridge and passive waveguide are parallel and from about 1 μm to about 8 μm apart at the nearest point.5. The waveguide structure of wherein the active waveguide and bridge are parallel and from about 2 μm to about 6 μm apart at the nearest point and the bridge and the passive waveguide are parallel and from about 1 μm to about 8 μm apart at the nearest point.6. A laser comprising:a. a gain material comprising at least two, compositionally non-identical, layers forming a superlattice, wherein the gain material generates photons by intersubband or interband transitions;b. at least two lasing sections placed in series, wherein each lasing section comprises gratings have non-equivalent periods or Bragg wavelengths, and wherein the lasing sections are separated by a electrical isolation region; and i. an active waveguide in contact with a gain material;', 'ii. at least one bridge; ...

SCANNING METHODS AND APPARATUS

There is provided a method of identifying a region of interest in sample. The method comprises obtaining one or more optical coherence tomography (OCT) axial scans at one or more locations over the sample surface; for each axial scan, determining an integrated total of OCT intensity over the depth of the scan, and determining an attenuation depth into the sample at which a predetermined fraction of the integrated total is reached; and determining the from the one or more attenuation depths a region of interest in the sample. Generally, the method does not rely the accuracy (or inaccuracy) of any particular scientific model of scattering and attenuation. It is therefore robust and can be employed across a wide variety of samples, including non-biological ones. 1. A method of identifying a region of interest in a sample , comprising:obtaining one or more optical coherence tomography (OCT) axial scans at one or more locations over the sample surface;for each axial scan, determining an integrated total of OCT intensity over the depth of the scan, and determining an attenuation depth into the sample at which a predetermined fraction of the integrated total is reached; anddetermining from the one or more attenuation depths a region of interest in the sample.2. The method as claimed in claim 1 , further comprising:generating an image of said sample, in which an indication of said attenuation depth is displayed at each respective location on the sample surface.3. The method as claimed in claim 2 , wherein the attenuation depth is indicated by a colour.4. The method as claimed in claim 1 , further comprising:for each axial scan, determining an attenuation coefficient by measuring a gradient of the OCT intensity in a region shallower than said attenuation depth.5. The method as claimed in claim 4 , further comprising:generating an image of said sample, in which an indication of said attenuation coefficient is displayed at each respective location on the sample surface.6. The ...

AUTOMATIC ANALYZING APPARATUS

An automatic analyzing apparatus which can make an adjustment to a target temperature so as to stabilize the light intensity of an LED and also can make the adjustment to that temperature in a short time is provided. The automatic analyzing apparatus in which an LED is used for a light source includes a temperature adjusting mechanism for the LED, and the temperature adjusting mechanism includes a metal member provided with the light source a pair of metal pipes (water-flowing pipes) buried in the metal member and allowing constant-temperature bath water to flow therein, and pins (small metal piece members) bringing only a heat-generating lead of the light source into direct contact with the metal member Therefore, the temperature adjusting mechanism can make an adjustment to a target temperature so as to stabilize the light intensity of the LED, and the adjustment to that temperature can be made in a short time. 1. An automatic analyzing apparatus comprising: a light-emitting diode light source; and a temperature adjusting mechanism for the light-emitting diode light source ,wherein the temperature adjusting mechanism is made up of: a metal member provided with the light-emitting diode light source; a water-flowing pipe buried in the metal member and allowing constant-temperature bath water to flow therein; and a small metal piece member bringing only a heat-generating lead of the light-emitting diode light source into direct contact with the metal member.2. The automatic analyzing apparatus according to claim 1 ,wherein a non-heat-generating lead of the light-emitting diode light source is covered with an insulating member.3. The automatic analyzing apparatus according to claim 1 ,wherein the water-flowing pipe is covered with an insulating member.4. The automatic analyzing apparatus according to claim 2 ,wherein the water-flowing pipe is covered with an insulating member. The present invention relates to an automatic analyzing apparatus which automatically ...

METHOD AND APPARATUS FOR ANALYTE DETECTION

Methods and apparatus for identifying an analyte in a sample are provided. The apparatus comprises an electromagnetic radiation (EMR) source in optical communication with a receptor. The receptor for receiving a sample and detecting if the sample has been presented to the receptor in a predefined manner. The receptor further directing the EMR received from the EMR source to the sample. The apparatus also comprises a detector in optical communication with the receptor, the detector for capturing transmitted, reflected, scattered EMR, or a combination thereof from the sample received from the receptor. The apparatus further comprises a user interface for presenting information obtained from the sample and the receptor, and the characteristics of one or more analytes in the sample, and a communications unit in operative association with the detector for transmitting the characteristics of one or more analytes in the sample to a processor or spectrograph. 1. An apparatus for determining the characteristics of one or more analytes in one or more sample , comprising ,an electromagnetic radiation (EMR) source;a receptor in optical communication with the EMR source, the receptor for receiving a sample, detecting if the sample has been presented to the receptor in a predefined manner, and directing EMR received from the EMR source at the one or more sample;a detector in optical communication with the receptor, the receptor for measuring transmitted, reflected, scattered EMR, or a combination thereof by the sample received from the receptor;a user interface for presenting information respecting the presentation of the sample to the receptor and the characteristics of one or more analytes in the sample; anda communications unit in operative association with the detector for transmitting the characteristics of one or more analytes in the sample to a processor.2. The apparatus of claim 1 , wherein the apparatus further comprises one or more spectrophotometers in communication ...

SIDE ILLUMINATED MULTI POINT MULTI PARAMETER

A side illuminated multi point multi parameter optical fiber sensor that requires no sensitive coating is provided. This sensor comprises an optical fiber having at least one removed cladding section as the sensitive region, at least one probing light source that side illuminates the fiber, a power supply, a detector, a signal processor and a display. The sensitive optical fiber is optically affected by the presence of a measurand medium that can fluoresce, phosphoresce, absorb and/or scatter the probing light. This probing light is guided by the fiber core towards a detector which measures the light intensity and this light intensity is correlated with a measurand. 1. An optical analytic subsystem comprising:a fiber optic configured to receive light that side illuminates the fiber at least at one location free of cladding and guide said light to at least one of its termini;at least one light source positioned and oriented to illuminate the side of said fiber optic at the at least one location; anda circuit configured to energize the light sources in a predetermined sequence.2. The optical analytic subsystem of where the at least one location and at least one light source are at least two locations and at least two respective light sources.3. The optical analytic subsystem of where the light source energization sequencing is serial.4. The optical analytic subsystem of where the light source energization sequencing is substantially simultaneous.5. The optical analytic subsystem of where the fiber core is tapered.6. The optical analytic subsystem of where at least one of the at least one light sources emits light in the far infrared spectrum.7. The optical analytic subsystem of where at least one of the at least one light sources is an UV LED.8. The optical analytic subsystem of where the fiber is plastic.9. The optical subsystem of further comprising a photodiode claim 2 , a photodiode amplifier and a light source power supply.10. A sensing system comprising:a) a ...

Method for drying a cellulose pulp web and a cellulose pulp dryer comprising an inspection device for inspecting the position of the web or the occurrence of web residue

A gas blowing cellulose pulp dryer is operative for drying a web of cellulose pulp using gas supplied from gas outlets of blow boxes of a first drying section. The cellulose pulp dryer has an inspection device with at least a first radiation sensor arranged to detect reflected radiation at the first drying section to detect at least one of a position of the web during operation of the dryer, and the occurrence of any residue of the web.

TEMPERATURE SENSOR AND METHOD FOR MEASURING A TEMPERATURE CHANGE

A temperature sensor is provided which comprises a measurement light source for generating measurement light and two optical waveguides. The two optical waveguides are arranged such that they respectively receive a measurement light portion of the measurement light and that the measurement light portions are superimposed after passing through the optical waveguides. Furthermore, the two optical waveguides have an optical property with different temperature dependency. 1. A temperature sensor comprising:a measurement light source for generating measurement light; andtwo optical waveguides, the two optical waveguides being arranged such that they respectively receive a measurement light portion of the measurement light and that the measurement light portions are superimposed after passing through the optical waveguides, and the two optical waveguides having an optical property with different temperature dependency.2. The temperature sensor according to claim 1 , wherein the optical property with different temperature dependency is the respective optical path length of the two optical waveguides.3. The temperature sensor according to claim 1 , wherein the two optical waveguides respectively have a light-conducting core and the two light-conducting cores are produced from different materials.4. The temperature sensor according to claim 1 , further comprising a light-splitting module for splitting the incoming measurement light into the measurement light portions and wherein the optical waveguides are respectively arranged at an outlet of the light-splitting module.5. The temperature sensor according to claim 1 , wherein the measurement light source is configured to irradiate the measurement light in the form of a directed beam onto the two optical waveguides claim 1 , the optical waveguides have respective input-side ends for receiving the measurement light portions and the input-side ends of the two optical waveguides are arranged so close to one another that the two ...

OPTICAL GAS SENSOR

An optical gas sensor with a light-emitting diode (), a photosensor (), a measuring section between the light-emitting diode and the photosensor, and a control and analyzing unit (), which is set up to determine the concentration of a gas in the measuring section from the light intensity measurement by the photosensor. The control and analyzing unit () is set up to measure the forward diode voltage over the light-emitting diode at a constant current, to determine the temperature of the light-emitting diode from the detected forward diode voltage over the light-emitting diode by means of a preset temperature dependence of the forward diode voltage, and to apply a correction function as a function of the light-emitting diode temperature determined, with which the measurement is converted to that of a preset temperature of the light-emitting diode. 1. An optical gas sensor comprising:a light-emitting diode;a photosensor;a measuring section between the light-emitting diode and the photosensor; anda control and analyzing unit determining a concentration of a gas in the measuring section from a light intensity measurement by the photosensor, the control and analyzing unit measuring a forward diode voltage over the light-emitting diode at a known current and determining a temperature of the light-emitting diode from the forward diode voltage detected over the light-emitting diode based on a preset dependence of the forward diode voltage on temperature, and applying a correction function that is a function of the light-emitting diode temperature determined, with which the measurement is converted to that of a preset temperature of the light-emitting diode.2. An optical gas sensor in accordance with claim 1 , wherein:the photo sensor is a photodiode; andthe control and analyzing unit operates the photodiode alternatingly in a mode for light intensity measurement and in a temperature-measuring mode, in which a preset current is applied to the photodiode and the resulting ...

Device for performing a blood, cell, and/or pathogen count and methods for use thereof

Devices and methods for performing a point of care blood, cell, and/or pathogen count or a similar blood test. Disclosed herein are systems that can be used to provide rapid, accurate, affordable laboratory-quality testing at the point of care. The systems described herein are capable of imaging and counting individual cells in a prepared cell sample (e.g., a peripheral blood smear or a blood sample prepared in a microfluidic device) or another prepared cell-containing sample without the need for a microscope or other expensive and cumbersome optics. The systems described herein are designed to eliminate or replace expensive, centralized clinical testing equipment and technical personnel. Such systems may include automated data reporting and decision support.

METHOD AND SYSTEM FOR INSPECTION OF IMAGE STICKING

A method for image sticking inspection of a light-transmissive device is disclosed. The light-transmissive device is responsive to application of a voltage to electrodes thereof to adjust light transmission characteristics. The method includes: providing light for passage through the light-transmissive device; applying a first alternating current (AC) voltage to the electrodes; applying a direct current voltage to the electrodes; and applying a second AC voltage to the electrodes, and measuring intensity of the light passing through the light-transmissive device during application of the second AC voltage. 1. A method for image sticking inspection of a light-transmissive device , the light-transmissive device being responsive to application of a voltage to electrodes thereof to adjust light transmission characteristics of the light-transmissive device , said method comprising:a) providing light for passage through the light-transmissive device;b) applying a first alternating current (AC) voltage to the electrodes of the light-transmissive device;c) applying a direct current (DC) voltage to the electrodes of the light-transmissive device after step b); andd) applying a second AC voltage to the electrodes of the light-transmissive device after step c), and measuring intensity of the light passing through the light-transmissive device during application of the second AC voltage.2. The method as claimed in claim 1 , wherein claim 1 , in step c) claim 1 , the DC voltage has a magnitude not less than 10 volts.3. The method as claimed in claim 2 , wherein claim 2 , in step c) claim 2 , the DC voltage has a magnitude not greater than 50 volts.4. The method as claimed in claim 2 , wherein claim 2 , in step c) claim 2 , the DC voltage is applied for a time period ranging from 1 minute to 20 minutes.5. The method as claimed in claim 1 , wherein each of the first and second AC voltages has a constant peak voltage.6. The method as claimed in claim 5 , wherein claim 5 , in step d ...

Devices Having One or More Integrated Computational Elements and Methods for Determining a Characteristic of a Sample by Computationally Combining Signals Produced Therewith

Optical computing devices containing one or more integrated computational elements may be used to produce two or more detector output signals that are computationally combinable to determine a characteristic of a sample. The devices may comprise a first integrated computational element and a second integrated computational element, each integrated computational element having an optical function associated therewith, and the optical function of the second integrated computational element being at least partially offset in wavelength space relative to that of the first integrated computational element; an optional electromagnetic radiation source; at least one detector configured to receive electromagnetic radiation that has optically interacted with each integrated computational element and produce a first signal and a second signal associated therewith; and a signal processing unit operable for computationally combining the first signal and the second signal to determine a characteristic of a sample. 1. A device comprising:a first integrated computational element and a second integrated computational element, each integrated computational element having an optical function associated therewith, and the optical function of the second integrated computational element being at least partially offset in wavelength space relative to that of the first integrated computational element;an optional electromagnetic radiation source;at least one detector configured to receive electromagnetic radiation that has optically interacted with each integrated computational element and produce a first signal and a second signal associated therewith; anda signal processing unit operable for computationally combining the first signal and the second signal to determine a characteristic of a sample.2. The device of claim 1 , wherein the signal processing unit determines a difference between the first signal and the second signal.3. The device of claim 1 , wherein each integrated ...

Methods and Devices for Optically Determining A Characteristic of a Substance

Optical computing devices are disclosed. One exemplary optical computing device includes an electromagnetic radiation source configured to optically interact with a sample and at least two integrated computational elements. The at least two integrated computational elements are configured to produce optically interacted light and further configured to be associated with a characteristic of the sample. The optical computing device further includes a first detector arranged to receive the optically interacted light from the at least two integrated computational elements and thereby generate a first signal corresponding to the characteristic of the sample. 1. A device , comprising:an electromagnetic radiation source configured to optically interact with a sample and at least two integrated computational elements, the at least two integrated computational elements being configured to produce optically interacted light and further configured to be associated with a characteristic of the sample; andat least one detector arranged to receive the optically interacted light from the at least two integrated computational elements and generate a first signal and a second signal, wherein the first signal and the second signal are computationally combined to determine the characteristic of the sample.2. The device of claim 1 , wherein the electromagnetic radiation source optically interacts with the at least two integrated computational elements after optically interacting with the sample.3. The device of claim 1 , wherein the electromagnetic radiation source optically interacts with the at least two integrated computational elements before optically interacting with the sample.4. The device of claim 1 , wherein the electromagnetic radiation source optically interacts with a first one of the at least two integrated computational elements before optically interacting with the sample and with a second one of the at least two integrated computational elements after optically ...

Methods and Devices for Optically Determining A Characteristic of a Substance

Optical computing devices are disclosed. One exemplary optical computing device includes an electromagnetic radiation source configured to optically interact with a sample and at least two integrated computational elements. The at least two integrated computational elements may be configured to produce optically interacted light, and at least one of the at least two integrated computational elements may be configured to be disassociated with a characteristic of the sample. The optical computing device further includes a first detector arranged to receive the optically interacted light from the at least two integrated computational elements and thereby generate a first signal corresponding to the characteristic of the sample. 1. A device , comprising:an electromagnetic radiation source configured to optically interact with a sample and at least two integrated computational elements, the at least two integrated computational elements being configured to produce optically interacted light, wherein at least one of the at least two integrated computational elements is configured to be disassociated with a characteristic of the sample; andat least one detector arranged to receive the optically interacted light from the at least two integrated computational elements and generate a first signal and a second signal, wherein the first signal and the second signal are computationally combined to determine the characteristic of the sample.2. The device of claim 1 , wherein each of the at least two integrated computational elements is configured to be disassociated with the characteristic of the sample.3. The device of claim 1 , wherein the characteristic of the sample is a first characteristic claim 1 , and wherein the at least one of the first and second integrated computational elements is configured to be associated with a second characteristic of the sample.4. The device of claim 1 , wherein the optically interacted light comprises a first beam of optically interacted light ...

Methods and Devices for Optically Determining A Characteristic of a Substance

Optical computing devices are disclosed. One exemplary optical computing device includes an electromagnetic radiation source configured to optically interact with a sample and at least two integrated computational elements. The at least two integrated computational elements may be configured to produce optically interacted light, and at least one of the at least two integrated computational elements may be configured to be disassociated with a characteristic of the sample. The optical computing device further includes a first detector arranged to receive the optically interacted light from the at least two integrated computational elements and thereby generate a first signal corresponding to the characteristic of the sample. 1. A method of determining a characteristic of a sample , comprising:optically interacting an electromagnetic radiation source with the sample and at least two integrated computational elements, wherein at least one of the at least two integrated computational elements is configured to be disassociated with the characteristic of the sample;producing optically interacted light from the at least two integrated computational elements;receiving with at least one detector the optically interacted light from the at least two integrated computational elements, thereby generating a first signal and a second signal; andcomputationally combining the first and second signals to determine the characteristic of the sample.2. The method of claim 1 , wherein each of the first and second integrated computational elements is configured to be disassociated with the characteristic of the sample.3. The method of claim 1 , wherein the at least one detector computationally combines the first and second signals.4. The method of claim 1 , wherein the at least one detector is a first detector claim 1 , the method further comprising:detecting with a second detector electromagnetic radiation from the electromagnetic radiation source;generate a third signal with the second ...

Methods and Devices for Optically Determining A Characteristic of a Substance

Optical computing devices are disclosed. One exemplary optical computing device includes an electromagnetic radiation source configured to optically interact with a sample and first and second integrated computational elements arranged in primary and reference channels, respectively. The first and second integrated computational elements produce first and second modified electromagnetic radiations, and a detector is arranged to receive the first and second modified electromagnetic radiations and generate an output signal corresponding to the characteristic of the sample. 1. A device , comprising:an electromagnetic radiation source configured to optically interact with a sample having a characteristic of interest;a first integrated computational element arranged within a primary channel and configured to optically interact with the electromagnetic radiation source and produce a first modified electromagnetic radiation;a second integrated computational element arranged within a reference channel and configured to optically interact with the electromagnetic radiation source and produce a second modified electromagnetic radiation; anda first detector arranged to receive the first and second modified electromagnetic radiations from the first and second integrated computational elements, respectively, and generate an output signal corresponding to the characteristic of the sample.2. The device of claim 1 , wherein the first detector is a split detector comprising a first detector portion arranged in the primary channel to receive the first modified electromagnetic radiation and a second detector portion arranged in the reference channel to receive the second modified electromagnetic radiation.3. The device of claim 2 , wherein the split detector computationally combines the first and second modified electromagnetic radiations to determine the characteristic of the sample.4. The device of claim 2 , wherein the output signal comprises a first output signal generated by the ...

Methods and Devices for Optically Determining A Characteristic of a Substance

Optical computing devices are disclosed. One exemplary optical computing device includes an electromagnetic radiation source configured to optically interact with a sample and first and second integrated computational elements arranged in primary and reference channels, respectively. The first and second integrated computational elements produce first and second modified electromagnetic radiations, and a detector is arranged to receive the first and second modified electromagnetic radiations and generate an output signal corresponding to the characteristic of the sample. 1. A method of determining a characteristic of a sample , comprising:optically interacting an electromagnetic radiation source with the sample and a first integrated computational element arranged within a primary channel and a second integrated computational element arranged within a reference channel;producing first and second modified electromagnetic radiations from the first and second integrated computational elements, respectively;receiving the first and second modified electromagnetic radiations with a first detector; andgenerating an output signal with the first detector, the output signal corresponding to the characteristic of the sample.2. The method of claim 1 , wherein the first detector is a split detector comprising a first detector portion arranged in the primary channel and a second detector portion arranged in the reference channel claim 1 , wherein receiving the first and second modified electromagnetic radiations further comprises:receiving the first modified electromagnetic radiation with the first detector portion; andreceiving the second modified electromagnetic radiation with the second detector portion.3. The method of claim 2 , further comprising computationally combining the first and second modified electromagnetic radiations with the first detector to determine the characteristic of the sample.4. The method of claim 2 , wherein the output signal comprises a first output ...

Methods and Devices for Optically Determining A Characteristic of a Substance

Optical computing devices are disclosed. One exemplary optical computing device includes an electromagnetic radiation source configured to optically interact with a sample and first and second integrated computational elements arranged in primary and reference channels, respectively, the first and second computational elements are configured to be either positively or negatively correlated to the characteristic of the sample. The first and second integrated computational elements produce first and second modified electromagnetic radiations, and a detector is arranged to receive the first and second modified electromagnetic radiations and generate an output signal corresponding to the characteristic of the sample. 1. A method of determining a characteristic of a sample , comprising:optically interacting an electromagnetic radiation source with the sample and a first integrated computational element arranged within a primary channel and a second integrated computational element arranged within a reference channel, wherein the first and second computational elements are configured to be positively or negatively correlated to the characteristic of the sample;producing first and second modified electromagnetic radiations from the first and second integrated computational elements, respectively;receiving the first and second modified electromagnetic radiations with a first detector; andgenerating an output signal with the first detector, the output signal corresponding to the characteristic of the sample.2. The method of claim 1 , wherein the first detector is a split detector comprising a first detector portion arranged in the primary channel and a second detector portion arranged in the reference channel claim 1 , wherein receiving the first and second modified electromagnetic radiations further comprises:receiving the first modified electromagnetic radiation with the first detector portion; andreceiving the second modified electromagnetic radiation with the second ...

Methods and Devices for Optically Determining A Characteristic of a Substance

Optical computing devices are disclosed. One exemplary optical computing device includes an electromagnetic radiation source configured to optically interact with a sample and first and second integrated computational elements arranged in primary and reference channels, respectively, the first and second computational elements are configured to be either positively or negatively correlated to the characteristic of the sample. The first and second integrated computational elements produce first and second modified electromagnetic radiations, and a detector is arranged to receive the first and second modified electromagnetic radiations and generate an output signal corresponding to the characteristic of the sample. 1. A device , comprising:an electromagnetic radiation source configured to optically interact with a sample having a characteristic of interest;a first integrated computational element arranged within a primary channel and configured to optically interact with the electromagnetic radiation source and produce a first modified electromagnetic radiation, wherein the first integrated computational element is configured to be positively or negatively correlated to the characteristic of interest;a second integrated computational element arranged within a reference channel and configured to optically interact with the electromagnetic radiation source and produce a second modified electromagnetic radiation, wherein the second integrated computational element is configured to be positively or negatively correlated to the characteristic of interest; anda first detector arranged to receive the first and second modified electromagnetic radiations from the first and second integrated computational elements, respectively, and generate an output signal corresponding to the characteristic of the sample.2. The device of claim 1 , wherein the first integrated computational element is configured to be positively correlated to the characteristic of interest and the second ...

Devices Having an Integrated Computational Element and a Proximal Interferent Monitor and Methods for Determining a Characteristic of a Sample Therewith

The output of optical computing devices containing an integrated computational element can be corrected when an interferent substance or condition is present. The devices may comprise an optional electromagnetic radiation source; a sample detection unit comprising an integrated computational element and a detector configured to receive electromagnetic radiation that has optically interacted with the integrated computational element and produce a sample signal associated therewith; an interferent monitor located proximal to the sample detection unit, the interferent monitor being configured to produce an interferent signal associated with an interferent substance; and a signal processing unit operable to convert the interferent signal into an interferent input form suitable for being computationally combined with the sample signal, the signal processing unit being further operable to computationally combine the sample signal and the interferent input form to determine a characteristic of a sample in real-time or near real-time. 1. A device comprising:an optional electromagnetic radiation source;a sample detection unit comprising an integrated computational element and a detector that is configured to receive electromagnetic radiation that has optically interacted with the integrated computational element and produce a sample signal associated therewith;an interferent monitor located proximal to the sample detection unit, the interferent monitor being configured to produce an interferent signal associated with an interferent substance; anda signal processing unit that is operable to convert the interferent signal into an interferent input form suitable for being computationally combined with the sample signal, the signal processing unit being further operable to computationally combine the sample signal and the interferent input form to determine a characteristic of a sample in real-time or near real-time.2. The device of claim 1 , wherein the sample detection unit ...

SPINNING FORCE APPARATUS

A spinning force system and methods of operation are provided for measuring a characteristic of a sample. The system includes a detection module having a light source for illuminating the sample and an objective being aligned to the light source to define a light path for producing an image of the sample. A rotor is mechanically coupled to the detection module and configured to rotate the light path for applying a force to the sample. The force may include a centrifugal force and other forms of force (such as a viscous drag force) resulted from the rotation. In some examples, the force is applied in a direction that is not parallel to a surface of the sample. 145-. (canceled)46. An apparatus for measuring a characteristic of a sample , the apparatus comprising:a detection module including a light source for illuminating the sample and an objective being aligned to the light source to define a light path for producing an image of the sample; anda rotor mechanically coupled to the detection module, the rotor being configured to rotate the light path for applying a force to the sample.47. The apparatus of claim 46 , wherein the detection module further includes a sensor for detecting the image of the sample and for generating electrical signals representative of the image.48. The apparatus of claim 47 , wherein the sensor includes a light detector.49. The apparatus of claim 48 , wherein the light detector includes a charge-coupled device.50. The apparatus of claim 47 , wherein the rotor is further configured to rotate the sensor at an angular velocity the same as that of the light path.51. The apparatus of claim 47 , wherein the sensor is stationary to a ground.52. The apparatus of claim 51 , wherein the detection module further includes a rotating mirror for directing a light signal generated by the objective to the sensor claim 51 , the light signal being representative of the image of the sample.53. The apparatus of claim 46 , wherein the detection module further ...

Measuring arrangement for optically evaluating a chemical reaction quantitatively

The invention relates to a measuring arrangement for optically evaluating a chemical reaction quantitatively, comprising a sample carrier having a carrier layer and a sample layer having an analysis side and a light outlet side opposite the analysis side, and comprising a photosensitive sensor having a plurality of photodetectors on a carrying body and having a transparent surface layer arranged over the photodetectors. A plurality of test sections are arranged on the analysis side at a distance from each other in a longitudinal direction of the sample layer. The analysis side is arranged on the carrier layer in such a way that the test sections face a volume of a microfluidic system. The sample carrier is detachably arranged in an accommodating device, so that the light outlet side faces the photosensitive sensor and the test sections are arranged over the photodetectors. Furthermore, the distance between the test sections and the photodetectors is less than 700 μm.

BIO-MOLECULE DETECTING DEVICE AND BIO-MOLECULE DETECTING METHOD

A bio-molecule detecting device that enables high-sensitivity measurement is provided. The bio-molecule detecting device was configured so that the orientation directions of free molecules and binding molecules in a solution are switched by switching the radiation direction of orientation control light, whereby the light extinction amount can be changed using nanorods associated with the free molecules and the binding molecules. In addition, between the free molecules and the binding molecules, there is a difference in the necessary time for the orientation direction to be switched by switching the radiation direction of the orientation control light, and therefore the timings, at which the light extinction amounts by the respective molecules change, are different. 1. A bio-molecule detecting device comprising:an orientation control unit that, in a solution including first complexes having a substance that can specifically bond to a specific bio-molecule and a detection label exhibiting anisotropic light absorption characteristics and second complexes in which the bio-molecule is specifically bonded to the first complexes through the substance, orients the first complexes and the second complexes in at least two directions;a first light source that radiates first light having a linearly-polarized light component in a specific direction on the solution;a detection unit that measures a light extinction amount of the first light by the solution; anda computation unit that carries out detection or quantity determination of the bio-molecule based on the light extinction amount of the light measured using the detection unit,wherein the first light is light having a wavelength at which the light extinction amount by the detection label is changed by a change in orientation directions of the first complexes and the second complexes.2. The bio-molecule detecting device according to claim 1 , wherein the first light is light in which changes in the orientation directions of ...

AIR-CONDITIONING DEVICE

A control/regulation unit and a sensor device in an air-conditioning device enable detecting presence of an analyte in room air to infer the quality of the room air. A light source emits light into the room on a light path that is reflected to a light-sensitive detector. The air-conditioning device is controlled/regulated as a function of an output of the detector. If the analyte is situated on the light path, the light is scattered and/or absorbed such that the detector detects a smaller quantity of light, on the basis of which it is possible to infer the presence of the analyte. The light source can be pivoted to set various light paths through the room to determine where the analyte is situated in the room based on the output of the detector for each light path. The air-conditioning device can controlled to selectively influence the atmospheric environment locally. 114-. (canceled)15. An air-conditioning device for influencing the atmospheric environment in a room , comprising:a control and regulation unit; and a radiation source emitting, during operation, radiation into the room on a beam path having a propagation direction pivotable over at least part of the room, such that various radiation paths through the room can be set, and', 'a detector, arranged such that at least part of the radiation emitted by the radiation source and diffusely reflected in the room during operation can fall directly or indirectly onto the detector which is sensitive to at least the radiation, the detector producing at least one output signal for the radiation paths that can be set, dependent on presence and/or concentration, in the beam path, of a specific analyte that is to be detected, and on a light quantity or an intensity of the radiation which falls on the detector, the control and regulation unit configured to control and/or regulate the air-conditioning device as a function of the output signal of the detector., 'at least one sensor device, each including'}16. The air- ...

Microfluidics System for Sequencing

A sensor chip () for use in multiplexed analysis of at least one sample is described. The sensor chip () comprises a plurality of sensing sites, each sensing site adapted for sensing an optional interaction of a sample with a component and an input waveguide for receiving radiation from a frequency comb radiation source and guiding said radiation along said plurality of sensing sites. At each sensing site, a distinct optical sensitive element is adapted for, at a distinct frequency, sensing an optional interaction of said sample with said component. An output means provides output of the radiation representative for the sensing dependent on said optional interaction of said sample with said component at said plurality of sensing sites. 1. A sensor chip for use in multiplexed analysis of at least one sample , the sensor chip comprisinga plurality of sensing sites, each sensing site adapted for sensing an optional interaction of a sample with a component,an input waveguide for receiving radiation from a frequency comb radiation source and guiding said radiation along said plurality of sensing sites,at each sensing site, a distinct optical sensitive element adapted for, at a distinct frequency of said radiation, sensing the optional interaction of said sample with said component, whereby the distinct frequency for said sensing is different for each sensing site,an output means for outputting radiation representative for said sensing dependent on said optional interaction of said sample with said component at said plurality of sensing sites.2. A sensor chip according to claim 1 , wherein the distinct optical sensitive element is a distinct optical resonator element adapted for at a distinct frequency of said radiation claim 1 , resonant radiation coupling between the input waveguide and the optical resonator element claim 1 , the resonant radiation coupling being dependent on the optional interaction of the sample with the component claim 1 , whereby the distinct ...

MEASURING DEVICE AND MEASURING METHOD

In a measurement device () including a measurement chamber (), in which an electromagnetic wave (), having a carrier frequency and modulated by a modulation frequency, acts on a sample, it is proposed to arrange an acoustic pickup (), which is tuned to the modulation frequency, outside of the measurement chamber () and to connect this acoustic pickup via acoustic decoupling means () to the measurement chamber () for detecting acoustic excitations () generated in the sample by the acting electromagnetic wave (). 11234266282962. A measurement device () for examining at least one constituent in a solid , liquid or gaseous sample , comprising a measurement chamber () for receiving the sample , a light source () configured to generate an electromagnetic wave () , interacting with the sample in the measurement chamber () , having a carrier frequency and a modulation frequency , the carrier frequency is tuned to the at least one constituent , and an acoustic pickup () , which is tuned to the modulation frequency , wherein the acoustic pickup () is arranged outside of the measurement chamber () and , in or on a wall () of the measurement chamber () , an acoustic decoupling element () is provided by which the acoustic pickup () is coupled acoustically to the sample situated in the measurement chamber ().216109. The measurement device () as claimed in claim 1 , wherein the acoustic pickup () comprises a resonator () claim 1 , which is connected to the acoustic decoupling element ().3191156. The measurement device () as claimed in claim 1 , wherein the acoustic decoupling element () comprises at least one of an acoustic window or a gas-tight or liquid-tight claim 1 , acoustic separation element () which is transmissive to an acoustic excitation () which is to be detected with or detectable by the acoustic pickup ().46125. The measurement device as claimed in claim 1 , wherein the acoustic pickup () comprises a resonance element () claim 1 , responding to acoustic excitations ...

Optical biosensor, bio-sensing system including the same, and method of fabricating the optical biosensor

An optical biosensor including a bio-sensing unit configured to receive an optical signal and generating a sensed optical signal, the wavelength of which varies according to a result of sensing a biomaterial; and a spectrometer including a plurality of ring resonators for dividing the sensed optical signal according to a wavelength and generating a plurality of output optical signals, respectively.

METHOD FOR MEASURING TOTAL CONCENTRATION OF OXIDIZING AGENTS, CONCENTRATION METER FOR MEASURING TOTAL CONCENTRATION OF OXIDIZING AGENTS, AND SULFURIC ACID ELECTROLYSIS DEVICE EQUIPPED WITH SAME

Provided are: a method of measuring the total concentration of oxidizing agents, by which the total concentration can be determined in a single measurement with simple operations even in an evaluation solution containing multiple components such as persulfuric acid, perosulfate and hydrogen peroxide; a simple and inexpensive concentration meter for measuring the total concentration of oxidizing agents; and a sulfuric acid electrolysis device comprising the concentration meter. 1. A method of measuring the total concentration of oxidizing agent(s) in an evaluation solution containing at least one oxidizing agent , said method being characterized by comprising at least the steps of:heat-treating said evaluation solution at 50 to 135° C. (heat treatment step); anddetecting hydrogen peroxide in the thus heat-treated evaluation solution (hydrogen peroxide detection step).2. The method according to claim 1 , wherein said evaluation solution comprises claim 1 , as said oxidizing agent claim 1 , at least one of peroxodisulfate ion claim 1 , peroxomonosulfate ion and hydrogen peroxide.3. The method according to claim 1 , wherein said evaluation solution has an acid concentration of 6 to 24 mol/l.4. The method according to claim 1 , wherein said heat treatment in said heat treatment step is performed for 2 to 70 minutes after the temperature of said evaluation solution reached a prescribed temperature.5. The method according to claim 1 , wherein hydrogen peroxide is detected in said hydrogen peroxide detection step by using any one selected from absorbance claim 1 , electrochemical process claim 1 , ultrasonic wave claim 1 , density and refractive index.6. The method according to claim 5 , wherein detection of hydrogen peroxide in said hydrogen peroxide detection step is performed by measuring the absorbance at a wavelength of 220 to 290 nm.7. The method according to claim 5 , wherein detection of hydrogen peroxide in said hydrogen peroxide detection step is performed by an ...

Optical waveguide having a varying index gradient

A photoacoustic detection device including a nanophotonic circuit including a first chip on which is formed at least one optical waveguide and in which is formed a set of cavities defining a Helmholtz resonator; at least one optical source capable of emitting an optical signal in a given wavelength range, capable of being modulated at an acoustic modulation frequency, this source being attached to the first chip; a second chip forming a cap for said cavities and including acoustic sensors; and electronic circuits for processing the output of the acoustic sensors formed in the first or the second chip. Further, an optical waveguide comprising, on a silicon substrate, a silicon germanium core with a variable germanium concentration along a direction perpendicular to the substrate, said core being covered with a cladding silicon layer.

DEFECT TESTER

A defect tester for detecting a defect in an article in a machine arrangement includes a starwheel having one or more pockets configured to hold respective one or more articles. The defect tester further includes one or more disks. Each of the one or more disks has one or more openings. Each of the one or more openings includes a covering configured to form a seal with an open end of the article. The defect tester further includes one or more detector units configured to detect a range of radiation wavelengths in an interior of the article. The radiation wavelengths are directed on an exterior of the article. The one or more detector units are further configured to communicate to a controller whether a defect has been detected. 1. A defect tester for detecting a defect in an article in a machine arrangement , the defect tester comprising:a starwheel having one or more pockets configured to hold respective one or more articles;one or more disks, each of the one or more disks having one or more openings, each of the one or more openings including a covering configured to form a seal with an open end of the article; andone or more detector units configured to detect a range of radiation wavelengths in an interior of the article, the radiation wavelengths being directed on an exterior of the article, the one or more detector units being further configured to communicate to a controller whether a defect has been detected.2. The defect tester of claim 1 , wherein the controller controls the defect tester and the machine arrangement.3. The defect tester of claim 1 , wherein the article is a can or a container.4. The defect tester of claim 1 , wherein the one or more disks is one disk claim 1 , the disk including the one or more detector units.5. The defect tester of claim 1 , wherein the one or more disks includes a first disk and a second disk claim 1 , the second disk being configured to cover the first disk such that the first and second disks are impermeable to ...

Cavity opto-mechanical sensor array

A mass sensor system including multiple Fabry-Perot microcavities connected in parallel by multiple waveguides. Each of the mass sensors includes a microbridge having a fundamental resonance frequency, and a movable reflective mirror etched into the microbridge; a fixed reflective mirror etched in a substrate, the fixed reflective mirror being fixed to the substrate in a region spaced apart from the movable reflective mirror; and an optical waveguide etched in the substrate that connects the movable mirror and the fixed mirror forming the Fabry-Perot microcavity interferometer. The system includes a tunable continuous-wave laser operative to optically interrogate the Fabry-Perot microcavity of each of the plurality of mass sensors, and a receiver operative to receive sensor signals from each of the plurality of mass sensors, the sensor signals comprising reflective signals and transmitted signals. A continuous-wave laser may generate optical forces that modify the motion, dynamics, or mechanical Q-factor of the microbridge.

Property measurement system for metal material

A property measurement system for a metal material includes: a laser oscillator that emits a pulse laser beam; a lens array that has small lenses with a same shape, the small lenses being laid in a matrix on a plane perpendicular to an optical axis of the pulse laser beam, and arranged so that a part of a cross section of the pulse laser beam can be made incident onto each of small lenses; a condensing lens that overlaps and condenses emitted beams coming from the small lenses on a same region of a surface of a metal material as a measurement target; a laser interferometer that detects, as an electric signal, a pulse ultrasonic wave that is excited by the pulse laser beam condensed and propagates through an inside of the metal material; and a signal processing device that processes the electric signal.

APPARATUS AND METHOD FOR ANALYZING GRAPHENE AND GRAPHENE BOUNDARY

A method of analyzing graphene includes providing a first graphene structure including graphene having grains and grain boundaries, and a support portion for supporting the graphene, generating a second graphene structure by oxidizing the first graphene structure, and detecting a shape of the graphene. 1. A method of analyzing graphene , the method comprising: graphene having grains and grain boundaries, and', 'a support portion for supporting the graphene;, 'providing a first graphene structure including,'}generating a second graphene structure by oxidizing the first graphene structure; anddetecting a shape of the graphene.2. The method of claim 1 , wherein the support portion is made of an oxidizable material.3. The method of claim 2 , wherein the support portion is made of metal.4. The method of claim 3 , wherein the support portion includes at least one of aluminum (Al) claim 3 , iron (Fe) claim 3 , cobalt (Co) claim 3 , nickel (Ni) claim 3 , copper (Cu) claim 3 , and palladium (Pd).5. The method of claim 1 , wherein the support portion comprises:a first support portion contacting the graphene, the first support portion made of metal; anda second support portion supporting the first support portion.6. The method of claim 1 , wherein the generating a second graphene structure comprises:{'sub': '2', 'disposing the first graphene structure in an environment including water vapor (HO) and oxygen (O); and'}irradiating ultraviolet (UV) rays to the first graphene structure.7. The method of claim 6 , further comprising:removing moisture after irradiating the UV rays.8. The method of claim 6 , wherein the disposing the first graphene structure includes disposing the first graphene structure in the environment having a humidity of about 20% to about 100%.9. The method of claim 1 , wherein the detecting a shape of the graphene includes using an optical microscope.10. The method of claim 1 , wherein the generating a second graphene structure by oxidizing the first graphene ...

SPECIMEN ANALYZING METHOD AND SPECIMEN ANALYZING APPARATUS

A specimen analyzing method and a specimen analyzing apparatus capable of measuring interference substances before analyzing a specimen. The method comprises a step for sucking the specimen stored in a specimen container () and sampling it in a first container (), a step for optically measuring the specimen in the first container, a step for sampling the specimen in a second container () and preparing a specimen for measurement by mixing the specimen with a reagent in the second container, and a step for analyzing the specimen for measurement according to the results of the optical measurement of the specimen. 1. A specimen analyzing method comprising steps of:sucking a specimen stored in a specimen container and sampling the specimen into a first container;optically measuring said specimen in said first container;sampling said specimen into a second container and preparing a measurement sample by mixing the specimen with a reagent in the second container; andanalyzing said measurement sample according to a result of the optical measurement of said specimen.2. The specimen analyzing method according to claim 1 , further comprising a step of determining whether or not to analyze said measurement sample prepared from said specimen according to the result of the optical measurement of said specimen claim 1 ,wherein the step of analyzing said measurement sample is performed so as to analyze said measurement sample when determining to analyze said measurement sample according to the results of the optical measurement of said specimen.3. The specimen analyzing method according to claim 1 , wherein the step of analyzing said measurement sample is performed so as to analyze said measurement sample by a first analyzing method when the result of the optical measurement of said specimen is in a first range and analyze said measurement sample by a second analyzing method when the result of the optical measurement of said specimen is in a second range.4. The specimen analyzing ...

LATERAL FLOW ASSAY SYSTEMS AND METHODS

In one aspect, a diagnostic test system includes a housing, a reader, and a data analyzer. The housing includes a port for receiving a test strip. The reader obtains separable light intensity measurements from localized regions of an area of the detection zone exposed for optical inspection, wherein each of the localized regions is characterized by at least one surface dimension smaller than the first dimension. The data analyzer identifies ones of the light intensity measurements obtained from the at least one test region and computes at least one parameter from the identified ones of the light intensity measurements. In another aspect, the reader obtains a respective set of light intensity measurements from each of multiple corresponding regions of the exposed surface area of the detection zone, and the data analyzer computes at least one parameter from at least one of the sets of light intensity measurements. 1. A diagnostic test system , comprising:a test strip comprising a detection zone containing an immobilized substance that binds a target analyte; a light source that illuminates the multiple localized regions of the detection zone; and', 'a light detector array that comprises individual light detectors, wherein the individual light detectors each obtain a separable light intensity measurement from one of the multiple localized regions of the detection zone; and, 'a reader that obtains separable light intensity measurements from multiple localized regions of the detection zone, wherein the reader comprisesa data analyzer comprising software that identifies ones of the light intensity measurements obtained from the detection zone and computes at least one parameter from the identified ones of the light intensity measurements.2. The diagnostic test system of claim 1 , wherein the detection zone comprises at least one test region claim 1 , and wherein the test strip supports lateral flow of a fluid along a lateral flow direction claim 1 , and wherein the ...

TEST DEVICE AND CONTROL METHOD THEREOF

A test device includes a microfluidic device to conduct a test for biomolecules and controlled to prevent errors in the test, and a control method thereof includes mounting a microfluidic device on a tray, positioning a rotary drive unit at a center of the microfluidic device, and moving the rotary drive unit up and down at least once such that the microfluidic device is seated on the rotary drive unit. 1. A control method of a test device comprising:mounting a microfluidic device on a tray;upon mounting the microfluidic device on the tray, positioning a rotary drive unit at a center of the microfluidic device; andmoving the rotary drive unit up and down at least once.2. The control method according to claim 1 , wherein claim 1 , in moving the rotary drive unit up and down at least once claim 1 , the center of the microfluidic device is coupled to a damper positioned at a housing.3. The control method according to claim 1 , wherein the rotary drive unit is coupled to a vertical movement unit and substantially moves up and down by vertical movement.4. The control method according to claim 3 , wherein the center of the microfluidic device is seated at a clamper positioned at an upper housing by vertical movement of the vertical movement unit.5. The control method according to claim 3 , wherein claim 3 , in mounting the microfluidic device on the tray claim 3 , the tray moves to a first state claim 3 ,wherein the tray is positioned at an exterior of a housing to allow the microfluidic device to be loaded onto the tray, andupon loading the microfluidic device onto the tray, the tray moves to a second state positioned at an interior of the housing.6. The control method according to claim 5 , wherein claim 5 , in the second state claim 5 , the vertical movement unit performs a first movement of moving upward and a second movement of moving downward at least once claim 5 , and the microfluidic device is coupled to the damper by the first movement.7. The control method ...

TEST DEVICE AND CONTROL METHOD THEREOF

A test device to detect a detection object of a microfluidic device and a control method thereof are provided. The test device includes a light emitting element configured to emit light onto the microfluidic device, a light receiving element configured to capture an image of the detection object through light emitted from the light emitting element, and a controller configured to determine a signal value of a predetermined area of the image of the detection object, and adjust an exposure level of the light receiving element according to a difference between the signal value and a predetermined target value. 1. A test device to detect a detection object of a microfluidic device , the test device comprising:a light emitting element configured to emit light onto the microfluidic device;a light receiving element configured to capture an image of the detection object through light emitted from the light emitting element; anda controller configured to determine a signal value for a predetermined area of the image of the detection object captured by the light receiving element, and adjust an exposure level of the light receiving element according to a difference between the signal value and a predetermined target value.2. The test device according to claim 1 , wherein the controller is configured to decrease the exposure level of the light receiving element if the signal value is greater than the predetermined target value.3. The test device according to claim 1 , wherein the controller is configured to increase the exposure level of the light receiving element if the signal value is less than the predetermined target value.4. The test device according to claim 1 , wherein the controller is configured to adjust the exposure level of the light receiving element by controlling at least one of a shutter speed and an iris opening of the light receiving element.5. The test device according to claim 1 , wherein the detection object comprises a test paper upon which a ...

VEHICLE MEASUREMENT SYSTEM

A vehicle measurement system includes a laser projector which is designed to generate suitable laser radiation during the vehicle measurement operation, and a laser protection device which is suitable for protecting people and objects from the laser radiation. The laser projector and the laser protection device are designed as separate components and are combinable to form a laser projector having a laser protection device and are separable from one another again. 110-. (canceled)11. A vehicle measurement system , comprising:a laser projector configured to generate laser radiation for vehicle measurement; anda laser protection device configured to protect persons and objects from the laser radiation generated by the laser projector;wherein the laser projector and the laser protection device are separate components which are configured to be (i) selectively combined to form an integrated system and (ii) subsequently separated again.12. The system as recited in claim 11 , wherein the laser projector is configured to be operable only when the laser projector is combined with the laser protection device.13. The system as recited in claim 12 , wherein the laser projector includes:a laser beam source;a diffraction grating; andone of a deflecting mirror or a deflecting prism positioned to deflect the laser beam generated by the laser beam source onto the diffraction grating.14. The system as recited in claim 12 , wherein the laser protection device is configured to be mountable directly on the laser projector.15. The system as recited in claim 12 , further comprising:a support configured to be mechanically connected to the laser projector and at least one camera.16. The system as recited in claim 15 , wherein one of (i) the laser protection device is configured to be mounted on the support claim 15 , or (ii) at least a portion of the support forms the laser protection device.17. The system as recited in claim 12 , wherein the laser protection device has at least one mirror ...

AUTOMATED PROTEIN ANALYZER

A dye binding method for protein analysis is disclosed. The method includes the steps of preparing an initial reference dye solution of unknown concentration from an initial reference dye concentrate and creating an electronic signal based upon the absorbance of the initial reference dye solution. Thereafter, an electronic signal is created based upon the absorbance of a dye filtrate solution prepared from the initial reference dye solution and an initial protein sample. The absorbance signals from the reference dye solution and the dye filtrate solution are sent to a processor that compares the respective absorbances and calculates the protein content of the protein sample based upon the difference between the absorbances. An electronic signal is created based upon the absorbance of a successive dye filtrate solution prepared from the reference dye solution and a successive protein sample, and the absorbance signal from the successive sample dye filtrate solution is sent to the processor to calculate the protein content of the successive sample based upon the difference between the absorbance of the initial reference dye solution and the absorbance of the successive dye filtrate solution. 1. A dye binding method for protein analysis comprising:preparing an initial reference dye solution of unknown concentration from an initial reference dye concentrate;creating an electronic signal based upon the absorbance of the initial reference dye solution;thereafter, creating an electronic signal based upon the absorbance of a dye filtrate solution prepared from the initial reference dye solution and an initial protein sample;sending the absorbance signals from the reference dye solution and the dye filtrate solution to a processor that compares the respective absorbances and calculates the protein content of the protein sample based upon the difference between the absorbances;creating an electronic signal based upon the absorbance of a successive dye filtrate solution ...

System and method for photoacoustic gas analysis

A system for analyzing gas concentrations in a gas mixture includes an array of semiconductor light sources which are configured to generate an electromagnetic radiation having a narrow bandwidth. A controller modulates the electromagnetic radiation at a modulating frequency to provide light pulses at an absorption wavelength of at least one target gas. The system also includes an acoustic resonant gas chamber to hold the gas mixture and configured to receive the light pulses and amplify acoustic signals emanating from the gas mixture. A processor determines a concentration of the target gas based on acoustic signals.

MICROPLATE FOR CORRELATIVE MICROSCOPY

The invention relates to a novel multiwell array comprising a plurality of wells, the majority of which have a unique cross-sectional shape whereby each well within the array can be identified and so tracked whilst the contents of the array are investigated. The invention also concerns a computer and a programmable data storage device for use with the array and an imaging apparatus including any one or more of the afore features or aspects. 1. A multiwell array comprising a plurality of wells wherein each well comprises:(a) a unique cross-sectional shape comprising at least one projection and/or indentation; and(b) a universal projection or indentation in the same position on each well so as to indicate a standard orientation or reference point for taking a reading of the number, nature and position of each projection and/or indentation on a selected well as one works about the well.2. The multiwell array according to wherein each well is provided with a unique non-random cross-sectional shape.3. The multiwell array according to wherein said unique non-random cross-sectional shape is provided along a substantial part of the depth or height of the well.4. The multiwell array according to wherein said unique non-random cross-sectional shape is provided along the entire depth or height of the well.5. The multiwell array according to wherein each well is provided with said unique cross-sectional shape having regard to the alignment of each well with respect to a selected axis claim 1 , so that wells of the same cross-sectional shape may be rotated with respect to said axis so as to provide different shapes when viewed from a fixed point.6. The multiwell array according to wherein each well is provided with a common cell accomodating region from which at least one projection protrudes and/or into which at least one indentation indents to thus give each well its unique crossectional shape.7. The multiwell array according to wherein each well comprises a plurality of ...

Analyzer Instrument And Methods For Operating Same

An instrument for optically measuring at least one property of a test medium, includes a light source for emission of light, a light management unit for guiding the light onto and/or into and through a detection space in the test medium, a light detection unit for detecting a fraction of the light scattered, reflected or transmitted by the test medium, a power management unit, and a data management unit. The instrument further includes or is coupled to a power source via a source wiring. The power management unit distributes energy from the power source via a buffer wiring to the light source, and via a further wiring to the light detection unit and the data management unit. The data management unit exchanges measurement data via signal wiring with the light detection unit with a receiving unit. The instrument is adapted to be operated in a potentially hazardous environment. 1. An instrument for optically measuring at least one property of a test medium , in particular a fluid , said instrument comprisingat least one light source for emission of light,at least one light management unit for guiding the light emitted by said light source onto and/or into and through a detection space in said test medium, and/or at least one light management unit for receiving at least a fraction of the light that has interacted with the test medium,at least one light detection unit for detecting at least a fraction of said light scattered, reflected, transmitted, and/or refracted by the test medium,at least one power management unit, andat least one data management unit,wherein said instrument further includes and/or is coupled to a power source via a source wiring,said power management unit distributes energy from the power source via a buffer wiring to at least said light source, and via at least one further wiring to at least said light detection unit and/or to said data management unit,said data management unit exchanges measurement data via one of said at least one further wiring ...