Automated method and apparatus for detecting erroneous sample collection in clinical assays

An automatic method for identifying biological samples that are collected using the wrong blood preservative for subsequent analytical testing. The method also provides for identification and/or suppression of certain analytical test results that are substantially or partly adversely affected. The invention is particularly suited for use in point-of-care medical diagnostic testing.

Sample analyzer and a sample analyzing method

Herewith disclosed is a sample analyzer comprising: a measurement section configured to perform a measurement on a sample and generate a measurement value according to the concentration of an analyte in the sample; a memory storing a calibration curve; an analysis section; an output section; and an instruction receiver. When the instruction receiver receives an instruction to perform a diluting measurement on a calibration sample, the measurement section dilutes the calibration sample by a predetermined ratio and performs a measurement on the diluted calibration sample, and the analysis section determines the concentration of the analyte in the diluted calibration sample by applying a measurement value obtained from the diluted calibration sample to the calibration curve. Information generated based on the determined concentration and the known concentration is output.

System and method for delta checking of biological samples

Methods of the invention automatically determine analytes and delta thresholds to use in delta checking patient data. The analytes and thresholds are determine from a populating specific set of patient data. Variance in analytes for multiple patient samples is determined. In additional, variance in intentionally mismatched patient samples is determined. The best analytes to differentiate between patients are determined along with delta thresholds. Preferred embodiments conduct evaluation with a multivariate delta threshold determination for ongoing testing of results from the patient. Preferred software provides an interactive interface that allows a user to set a number of flags that can be handled per a predetermined time period, and automatically adjusts the delta threshold to that number of flags.

Systems and methods for detecting fallen containers suitable for apparatus for automated evaluation of microorganism growth in test samples

Methods, systems, computer program products, apparatus and circuits are configured to detect fallen containers upstream or proximate an intake zone suitable for automated evaluation apparatus using different sensors, including at least one lower sensor and at least one upper sensor which is positioned to project an optical signal at a height corresponding to a top portion of an upright container to thereby allow an increased reliability in detection of different orientations and positions of fallen containers. An optional second lower sensor may be used which is longitudinally spaced apart from the first lower sensor and the lower sensors can transmit optical signals across the container travel path that do not intersect.

Sample analysis system and sample analyzer

A sample analysis system includes a first measurement unit, a second measurement unit arranged to a downstream side of the first measurement unit, and an information processing section which obtains a measurement result of a sample. The information processing section determines, based on the measurement result of the sample measured by the first measurement unit, whether or not a retest of the sample by the first measurement unit is necessary. When the retest by the first measurement unit is necessary, the information processing section causes the sample container to be transported to a first sample supply position for the first measurement unit and causes the first measurement unit to perform measurement of the sample.

Facing and Quality Control in Microtomy

The present disclosure also relates to systems and methods for quality control in histology systems. In some embodiments, a method is provided that includes receiving a tissue block comprising a tissue sample embedded in an embedding material, imaging the tissue block to create a first imaging data of the tissue sample in a tissue section on the tissue block, removing the tissue section from the tissue block, the tissue section comprising a part of the tissue sample, imaging the tissue section to create a second imaging data of the tissue sample in the tissue section, and comparing the first imaging data to the second imaging data to confirm correspondence in the tissue sample in the first imaging data and the second imaging data based on one or more quality control parameters. 1. A method for quality control in histology system comprising:receiving a tissue block comprising a tissue sample embedded in an embedding material;imaging the tissue block, prior to removing one or more tissue sections, to generate a baseline imaging data of the tissue sample;imaging the tissue block to create a first imaging data of the tissue sample in a tissue section of the one or more tissue sections on the tissue block;removing the tissue section from the tissue block, the tissue section comprising a part of the tissue sample;imaging the tissue section to create a second imaging data of the tissue sample in the tissue section;comparing the first imaging data to the second imaging data to confirm correspondence in the tissue sample in the first imaging data and the second imaging data based on one or more quality control parameter; andcomparing the first imaging data, the second imaging data or both to the baseline imaging data.2. The method of claim 1 , wherein the tissue section is non-confirming if there is no correspondence in one or more quality control parameters in the tissue sample in the first imaging data and the second imaging data.3. The method of claim 2 , wherein the one ...

Facing and Quality Control in Microtomy

The present disclosure relates to systems and methods for tracking and printing within a histology system. In some embodiments, a system is provided that includes an information reader configured to read identifying data associated with a tissue block, a microtome configured to cut one or more tissue sections from the tissue block, one or more slides for receiving the one or more tissue sections, and a printer configured to receive the identifying data and print, after the one or more tissue sections are cut from the tissue block, one or more labels for the one or more slides, the one or more labels comprising information associating the one more tissue sections on the one or more slides with the tissue block. 1. A system comprising:an information reader configured to read identifying data associated with a tissue block;a microtome configured to cut one or more tissue sections from the tissue block;one or more slides for receiving the one or more tissue sections;a printer configured to receive the identifying data and print, after the one or more tissue sections are cut from the tissue block, one or more labels for the one or more slides, the one or more labels comprising information associating the one more tissue sections on the one or more slides with the tissue block; anda visualization system configured to track the one or more tissue sections from the microtome to the one or more slides as the one or more tissue sections are being transferred from the microtome to the one or more slides.2. The system of claim 1 , wherein the visualization system is configured to make a comparison between the one or more tissue sections on the one or more slides with one or more images of the tissue block or the image of the section on a transfer medium.3. The system of claim 2 , wherein the visualization system is configured to make a comparison between the one or more tissue sections on the one or more slides claim 2 , on the tissue block or the transfer medium with a ...

REFLEX TESTING OF SAMPLES USING RESIDUAL MATERIALS FROM A PRIOR TEST

Embodiments disclosed herein relate to methods and systems for performing automated assays, and particularly to performing sequential assays on a sample on an automated instrument. 1. A method of performing an automated assay on a plurality of specimens , said method comprising:a) providing an automated instrument configured to receive and process a plurality of samples from said plurality of specimens for one or more target analytes according to one or more respective assay workflows;b) providing a plurality of samples to be tested;c) automatically transferring a first portion of each of said plurality of samples to be tested to a respective plurality of first vessels that comprise reagents for a first test for a first target analyte;d) automatically performing the first test on the portion of said plurality of samples to determine the presence of a first target analyte according to a first assay workflow;e) selecting a subset samples from the plurality of samples in which the presence of the first target analyte was determined;f) automatically transferring a second portion of the selected subset of samples from e) to a second vessel comprising reagents for a second test to determine the presence of a second target analyte according to a second assay workflow; andg) automatically performing the second test on the second portion of the selected subset of samples.2. The method of claim 1 , wherein each of the plurality of samples comprises a pre-processed solution of isolated nucleic acids from a respective plurality of specimens.3. The method of claim 2 , wherein the automated instrument automatically processes the plurality of specimens to obtain the respective plurality of samples comprising isolated nucleic acids.4. The method of claim 1 , wherein claim 1 , for each sample claim 1 , said sample and said first vessel comprising reagents for a first test are located on a first test strip claim 1 , andwherein step f) further comprises automatically transferring the ...

TUBE CHARACTERIZATION STATION

Systems and methods for use in an in vitro diagnostics setting may include an automation track, a plurality of carriers configured to carry a plurality of sample vessels along the automation track, and a characterization station including a plurality of optical devices. A processor, in communication with the characterization station, can be configured to analyze images to automatically characterize physical attributes related to each carrier and/or sample vessel. A method may include receiving a plurality of images from a plurality of optical devices of a characterization station, wherein the plurality of images comprise images from a plurality of perspectives of a sample vessel being transported by a carrier, automatically analyzing the plurality of images, using a processor, to determine certain characteristics of the sample vessel, and automatically associating the characteristics of the sample vessel with the carrier in a database. 1. An automation system for use in an in vitro diagnostics setting comprising:an automation track;a plurality of carriers configured to carry a plurality of sample vessels along the automation track;a characterization station comprising a plurality of optical devices; anda processor, in communication with the characterization station, configured to analyze images to automatically characterize at least one physical attribute related to each carrier.2. The automation system of claim 1 , wherein the at least one physical attribute comprises an orientation of at least one sample vessel relative to each carrier.3. The automation system of claim 2 , wherein the orientation comprises at least one of a linear offset or rotational offset relative to a nominal position.4. The automation system of claim 1 , wherein the at least one physical attribute comprises physical dimensions of at least one sample vessel carried by each carrier.5. The automation system of claim 1 , wherein the at least one physical attribute comprises an identification of a ...

Facing and Quality Control in Microtomy

The present disclosure relates to systems and methods for facing a tissue block. In some embodiments, a method is provided for facing a tissue block that includes imaging a tissue block to generate imaging data of the tissue block, the tissue block comprising a tissue sample embedded in an embedding material, estimating, based on the imaging data, a depth profile of the tissue block, wherein the depth profile comprises a thickness of the embedding material to be removed to expose the tissue sample to a pre-determined criteria, and removing the thickness of the embedding material to expose the tissue to the pre-determined criteria. 1. A method for facing a tissue block comprising:imaging a tissue block to generate imaging data of the tissue block, the tissue block comprising a tissue sample embedded in an embedding material;estimating, based on the imaging data, a depth profile of the tissue block, wherein the depth profile comprises a thickness of the embedding material to be removed to expose the tissue sample to a predetermined criteria; andremoving the thickness of the embedding material to expose the tissue sample to the predetermined criteria,wherein the tissue block is imaged with a structured light to determine the depth profile.2. The method of claim 1 , further comprising:progressively removing one or more sections from a tissue block comprising a tissue sample embedded in an embedding material;imaging the one or more sections to generate imaging data associated with the one or more sections; andconfirming, based on the imaging data, that the tissue sample is exposed to the predetermined criteria.3. A method for facing a tissue block comprising:illuminating the tissue block with a structured light in a UV range;imaging the tissue block, prior to removing the one or more sections, to generate a baseline imaging data of the tissue sample progressively removing one or more sections from a tissue block comprising a tissue sample embedded in an embedding ...

COMPUTER-IMPLEMENTED METHOD AND SYSTEM FOR SPECTROSCOPIC ANALYSIS OF BIOLOGICAL MATERIAL

A computer-implemented method for spectroscopic analysis of biological material is provided that includes analyzing samples of biological material from a plurality of sources, and delivering samples of biological material to at least one flow cell for spectroscopy, and determining whether the spectroscopic analysis for each sample of the plurality of samples is or is predicted to be ambiguous in that it is affected by at least two non-discriminable factors. If such a determination is made, a disambiguating step can be performed. 1. A computer-implemented method for spectroscopic analysis of biological material , the method including an analysis step comprising:taking, by a liquid router, a plurality of samples of biological material from a plurality of sources, wherein each sample of the plurality of samples is taken from a source of the plurality of sources;delivering, by the liquid router, the plurality of samples of biological material to at least one flow cell for spectroscopy;performing, by at least one spectrometer connected to the at least one flow cell, the spectroscopic analysis of the plurality of samples of biological material;determining whether the spectroscopic analysis for each sample of the plurality of samples is or is predicted to be ambiguous in that it is affected by at least two non-discriminable factors; andupon determining that the spectroscopic analysis for a given sample of the plurality of samples of biological material is or is predicted to be ambiguous, performing a first disambiguating step or a second disambiguating step, routing, by the liquid router, the given sample of biological material from the at least one flow cell to a manipulation station;', 'manipulating, at the manipulation station, the given sample of biological material in order to impact the spectroscopic analysis;', 'delivering, by the liquid router, the given manipulated sample of biological material from the manipulation station to the at least one flow cell; and', ' ...

COMBINED DETECTION INSTRUMENT FOR CULTURE SPECIMEN CONTAINERS AND INSTRUMENT FOR IDENTIFICATION AND/OR CHARACTERIZATION OF A MICROBIAL AGENT IN A SAMPLE

A detection instrument determines whether a specimen container (e.g., blood culture bottle) is positive for presence of microbial agent growth therein. When the container is deemed positive it is made available (e.g, transferred or exposed to) to an automated instrument performing identification and/or characterization of the microbial agent. The identification and/or characterization instrument removes a portion of the sample from the specimen container and places it into a disposable separation and concentration device. The microbial agent is concentrated via optional selective lysis of non-microbial agent cellular material which may be present and centrifugation. A reading module reads the concentrated microbial agent using spectroscopic methods, e.g., measurements of intrinsic fluorescence. Such interrogation may occur while the microbial agent remains concentrated in the disposable device. 1. (canceled)2. An automated system for rapid detection of a microbial agent in a sample and identifying the microbial agent , comprising , in combination:a detection instrument receiving a specimen container containing a sample, the detection instrument including a heated enclosure for incubating the specimen container and a detection unit interrogating the specimen container to detect whether the specimen container is positive for the presence of a microbial agent in the sample;a supply of disposable separation devices; and a sample removal apparatus operative to remove a portion of the sample from the specimen container and add the portion to a separation device obtained from the supply of separation devices;', 'a separation and concentration station operative on the separation device after receiving the portion of the sample so as to separate the microbial agent from other products in the sample and concentrate the microbial agent within the separation device;', 'a centrifuge located within the separation and concentration station, the centrifuge capable of concentrating ...

PATIENT-BASED RESULTS DISPLAY

A medical testing machine provides improved recall and display of the outcomes of tests performed by the machine. Test outcomes and other information are stored in mass storage directly accessible by the medical testing machine. In one aspect, outcomes of tests relating to a particular patient may be recalled. The system may be especially useful for tests that may be performed multiple times for a particular patient over a period of time, for example testing for HbA1c hemoglobin levels in diabetes patients. According to another aspect, the medical testing machine may store an accession number for each test outcome, and may enable a user to display as a group test outcomes having the same accession number. The system may store further information and associate it with particular test outcomes, for example calibration information. The system may also store a set of rules under which each test instance was run. 1. A medical testing machine , comprising:an input location, an output location, and a vial handling mechanism that moves vials of media sampled from patients from the input location through the testing machine to the output location;an extraction mechanism that extracts the media from each vial in turn for testing;a testing system that performs a medical test on the media sampled from patients, each test instance having an outcome;a reader that obtains, for each of a plurality of test instances, an identifier of the particular patient from which the media was sampled by reading the identifier from a container that holds the media;a processor that receives the output of the sensor and determines the outcome for each respective test and that causes test outcomes to be stored in a mass storage memory in association with their respective patient identifiers; anda computerized retrieval system that enables a user to specify a particular patient identifier and causes the computerized retrieval system to retrieve from the mass storage memory test outcomes associated ...

Inspection Device

In medical analysis devices and automatic specimen examination systems, the specimen conveyance mechanism is constituted by a plurality of belt lines. During installation or maintenance of the specimen conveyance mechanism, it is necessary to confirm the existence of steps at the joints of these belt lines and the parallelism of the conveyance line. According to the present invention, it is possible to lighten the burden of this work with a test tube type or conveyance holder type inspection device provided with a sensor and battery for operation. Also, even when an operator cannot visually confirm the conveyance line from outside, it is possible to confirm the state of the conveyance line. 1. An inspection device comprising:an accommodation body having an external shape that can be detachably held by a conveyance body that is capable of holding a test tube and conveying the test tube over a conveyance belt;a sensor that is provided in the accommodation body and detects a state in a device during the conveyance;a storage unit that stores output data from the sensor; anda transmission unit that transmits data in the storage unit to an outside.2. The inspection device according to claim 1 ,wherein the sensor is at least one of an acceleration sensor, an angular velocity sensor, an inclination sensor, a microphone, an illuminance sensor, and a temperature sensor.3. The inspection device according to claim 1 ,wherein the sensor is an imaging element, andwherein the transmission unit is means for transmitting, to an external computer, an image captured by the imaging element.4. The inspection device according to claim 1 , further comprising:a storage medium that is capable of writing, in a non-contact manner, positional information from a writing antenna disposed in the vicinity of a conveyance route during the conveyance by the conveyance body.5. The inspection device according to claim 1 ,wherein, in a state in which the sensor, the storage unit, and the transmission ...

SAMPLE TESTING SYSTEM WITH AUTOMATED CONTROL OF SAMPLE RETESTING

A sample testing system comprising: a transporting apparatus; a testing apparatus for obtain a sample and performing testing on the obtained sample; and a controller. The controller executes operation of: controlling the transporting apparatus so as to transport the sample rack in first direction, such that each sample container held in a sample rack is transported to a obtaining position on which the testing apparatus obtains a sample and then the sample rack is transported toward the second position; changing, when retesting of a sample contained in a sample container is necessary, the transporting direction from the first direction to second direction, and then controlling the transporting apparatus so as to transport the sample container accommodating the sample, for which retesting is necessary, to the obtaining position again. Sample testing method and a computer program product are also disclosed. 121-. (canceled)22. A sample testing method comprising:transporting, from an input buffer, a sample rack comprising a plurality of holding positions for holding a plurality of sample containers, respectively;reading a label attached to the sample container;after the label is read, transporting the sample rack to a sample handling position where the sample container is provided to test a sample contained in the sample container;aspirating and testing the sample contained in the sample container held at each of the plurality of holding positions;after the sample contained in the sample container held at a last holding position of the plurality of holding positions is aspirated, transporting the sample rack to a parking position; andperforming a retesting, according to the holding position of the sample container subjected to the retesting, (i) before the sample rack is transported to the parking position or (ii) after the sample rack is transported to the parking position and then transported back to the sample handling position.23. The sample testing method according ...

Sample testing system with automated control of sample retesting

A sample testing system comprising: a transporting apparatus; a testing apparatus for obtain a sample and performing testing on the obtained sample; and a controller. The controller executes operation of: controlling the transporting apparatus so as to transport the sample rack in first direction, such that each sample container held in a sample rack is transported to a obtaining position on which the testing apparatus obtains a sample and then the sample rack is transported toward the second position; changing, when retesting of a sample contained in a sample container is necessary, the transporting direction from the first direction to second direction, and then controlling the transporting apparatus so as to transport the sample container accommodating the sample, for which retesting is necessary, to the obtaining position again. Sample testing method and a computer program product are also disclosed.

REFLEX TESTING OF SAMPLES USING RESIDUAL MATERIALS FROM A PRIOR TEST

Embodiments disclosed herein relate to methods and systems for performing automated assays, and particularly to performing sequential assays on a sample on an automated instrument. 125.-. (canceled)26. A system comprising:an automated instrument comprising a code reader, the automated instrument configured to receive a plurality of samples to be tested for target analytes;a processor; and scan, via a code reader included in the automated instrument, indicia on vessels that contain the plurality of samples;', 'store, via the automated instrument, indicia on the vessels that contain the plurality of samples;', 'automatically transfer, via the automated instrument, a first portion of each sample of the plurality of samples to a respective plurality of first lanes;', 'automatically perform, via the automated instrument, a first test for a first target analyte on a first solution comprising the first portions of the plurality of samples and first reagents according to a first assay workflow, the first test providing a result indicating a presence of the first target analyte in a subset of samples from the plurality of samples;', 'select, via the automated instrument, the subset of samples from the plurality of samples;', 'assign each of the subset of samples from the plurality of samples to a second lane of the plurality of second lanes, wherein identifying indicia on the vessels that contain the plurality of samples used in the first assay workflow are accessed via the automated instrument to process the subset of samples during a second assay workflow, wherein the identifying indicia identifies the position of the first lane and the second lane relative to other lanes;', 'automatically transfer, via the automated instrument, a second portion of each of the subset of samples to a respective plurality of second lanes; and', 'automatically perform, via the automated instrument, the second test for a second target analyte on a second solution comprising the second portion ...

SAMPLE ANALYZER

A sample analyzer is provided that does not require a plurality of reagent containers containing the same type of reagent to be connected, that can continue measurement even when a reagent container becomes empty, and that allows the timing of replacement of the reagent container to be recognized suitably. A reagent storage section is provided that is connected to a reagent container containing a reagent through a fluid channel and that stores the reagent transferred from the reagent container. A message for prompting replacement of the reagent container is outputted when it is detected that the remaining amount in the reagent container is a predetermined amount or less. A message for prompting to suspend sample measurement in the measurement section is outputted when it is detected that the remaining amount in the reagent storage section is a predetermined amount or less. 1. A sample analyzer , comprising:a reagent storage section that is connected to a reagent container containing a reagent through a fluid channel and that stores the reagent transferred from the reagent container;a measurement section that is connected to the reagent storage section through a fluid channel and that measures a sample using the reagent;a transfer unit that transfers the reagent from the reagent container to the reagent storage section and then from the reagent storage section to the measurement section;a reagent container remaining amount detection means for detecting that the remaining amount in the reagent container is a predetermined amount or less; anda replacement message output means that outputs a message for prompting replacement of the reagent container when the reagent container remaining amount detection means detects that the remaining amount in the reagent container is the predetermined amount or less.2. The sample analyzer according to claim 1 , further comprising:a storage remaining amount detection means for detecting that the remaining amount in the reagent storage ...

BLOOD INSPECTION DEVICE

This blood inspection device is for inspecting blood in a blood collection tube. The blood inspection device comprises an output unit for outputting, to the outside, first information about the anticoagulants that can and cannot be used for each inspection item. 1. A blood testing device for testing blood in a blood collection tube , the blood testing device comprising an output that externally outputs first information about usable anticoagulants or unusable anticoagulants for respective test items.2. The blood testing device according to claim 1 , further comprising:an input used to enter second information about an anticoagulant contained in the blood collection tube; anda controller that compares the second information entered via the input with the first information and determines whether the anticoagulant contained in the blood collection tube is usable for testing a specific test item, whereinthe output further externally outputs a determination result produced by the controller.3. The blood testing device according to claim 2 , wherein as information about each anticoagulant claim 2 , the first information and the second information contain a name of the anticoagulant claim 2 , a character code corresponding to the anticoagulant claim 2 , a color code corresponding to the anticoagulant and marked on a cap of the blood collection tube claim 2 , or a combination thereof.4. The blood testing device according to claim 3 , wherein the color code is a color code defined by JIS T 3233 claim 3 , ISO 6710 claim 3 , or CLSI GP41-A6.5. The blood testing device according to claim 3 , wherein the color code is a color code set arbitrarily for the anticoagulant.6. The blood testing device according to claim 2 , wherein the output outputs the first information claim 2 , or the first information and the determination result as visual information including at least either characters or graphics.7. The blood testing device according to claim 2 , wherein the output outputs the ...

TUBE CHARACTERIZATION STATION

Systems and methods for use in an in vitro diagnostics setting may include an automation track, a plurality of carriers configured to carry a plurality of sample vessels along the automation track, and a characterization station including a plurality of optical devices. A processor, in communication with the characterization station, can be configured to analyze images to automatically characterize physical attributes related to each carrier and/or sample vessel. A method may include receiving a plurality of images from a plurality of optical devices of a characterization station, wherein the plurality of images comprise images from a plurality of perspectives of a sample vessel being transported by a carrier, automatically analyzing the plurality of images, using a processor, to determine certain characteristics of the sample vessel, and automatically associating the characteristics of the sample vessel with the carrier in a database. 1. A characterization station configured for use with an automation system comprising:a plurality of optical devices configured to capture one or more images of a carrier on an automation track; anda processor configured to analyze the one or more images to determine at least one physical attribute of the carrier or an object being transported by the carrier.2. The characterization station of claim 1 , wherein the processor is configured to determine which claim 1 , if any claim 1 , of a plurality of slots in each carrier is occupied.3. The characterization station of claim 1 , wherein the at least one physical attribute comprises an orientation of the object relative to the carrier.4. The characterization station of claim 3 , wherein the orientation comprises at least one of a linear offset or rotational offset relative to a nominal position.5. The characterization station of claim 1 , wherein the at least one physical attribute comprises physical dimensions of the object being transported by the carrier.6. The characterization ...

CONNECTED SYSTEMS FOR AUTOMATED TISSUE SECTION PREPARATION AND METHODS OF USE THEREOF

Systems and methods enable fully automated tissue processing using tissue processing components for producing tissue sections from a tissue sample block and to transfer the tissue sections to slides. A control device queries a Laboratory Information Management System (LIMS) with a sample identifier associated with the tissue sample block and receives tissue sample data from the LIMS. The control device generates tissue processing workflow parameters based on the tissue sample data for each tissue processing component to perform an automated tissue processing workflow. The control device automatically controls each tissue processing component according to the tissue processing workflow parameters to process the tissue sample block. The control device generates a block processing update message while the tissue sample block is processed and communicates the block processing update message to the LIMS to enable the LIMS to track the automated tissue processing workflow for the tissue sample block. 1. A system comprising:one or more tissue processing components configured to produce one or more tissue sections from a tissue block and to transfer the one or more tissue sections from the tissue block to one or more slides; and query the LIMS with a sample identifier associated with a tissue sample block and receive tissue sample data from the LIMS;', 'generate tissue processing workflow parameters based on the tissue sample data received from the LIMS for each tissue processing component to perform an automated tissue processing workflow;', 'automatically control each tissue processing component according to the tissue processing workflow parameters to process the tissue sample block;', 'generate at least one block processing update message while the tissue sample block is processed; and', 'communicating the at least one block processing update message to the LIMS so as to enable the LIMS to track the automated tissue processing workflow associated with the tissue sample ...

Specimen Conveyance System and Specimen Conveyance Method

A specimen conveyance system and a specimen conveyance method are realized, in which a conveyance route of a specimen can be reset even when information about an additional request is received after loading of the specimen. When an abnormality occurs in the analysis result, a notification of the abnormality is sent to an operation control unit and a host computer through a communication cable and information about the additional request for changing the conveyance route is created. After the specimen is conveyed from the analysis device to the transfer machine, information about the additional request is checked at a destination determination point, and the conveyance route is changed according to the additional request. Accordingly, the specimen container can be conveyed to the appropriate analysis device without being returned to the storage unit once, and thus the specimen analysis time can be reduced. 1. A specimen conveyance system comprising:a loading unit where a specimen is loaded;a conveyance line where the specimen is conveyed in both directions;a plurality of analysis devices that are connected to the conveyance line and analyze the specimen based on examination items of the specimen;a storage unit that collects and accommodates the specimen; andan operation control unit that sets a conveyance route of the specimen before the specimen is conveyed through the conveyance line, whereinwhen an additional examination item is requested for the specimen while the specimen is conveyed through the conveyance line to be collected by the storage unit, the operation control unit resets a conveyance route of the specimen including an analysis device that analyzes the additional examination item.2. The specimen conveyance system according to claim 1 , further comprisinga transfer machine that is connected to each of the plurality of analysis devices and the conveyance lines and conveys the specimen into and out from the analysis device and the conveyance line connected ...

Sample inspection automation system and sample transfer method

The invention provides a sample inspection automation system capable of easily, reliably, and efficiently responding to requests for reinspection or addition of inspection items. The sample inspection automation system includes a storage unit having a sample replacing mechanism for transferring a sample from a tray to a sample transfer line. When the system receives sample retrieval information through the communication between an operating unit and a laboratory information system (LIS), or a host system of the sample inspection automation system, the sample is transferred to the appropriate sample treatment unit through the transfer line. Thus, when a request for reinspection or addition inspection is issued, the sample inspection automation system can efficiently respond to it.

Examination system, examination device, and examination method

The present invention optically obtains characteristic values of a plurality of biological samples from a specimen; compares the characteristic values with examination information associated with the same specimen obtained in advance; and calculates an indicator to determine, based on a result of the comparison, whether a process is continued to genetic analysis of the biological samples or a re-preparation of samples from the same specimen is performed. By this method, it is possible to achieve more reliable biomarker detection by ensuring validity through appropriate selection of test samples while reducing cost, effort, and time for analysis in single cell analysis or analysis of a group of a small number of cells.

TEST INSTRUMENT AND METHOD OF CONTROLLING THE SAME

Disclosed herein are a test instrument and a method of controlling the same, capable of performing a basic test on a sample of a patient, determining whether to perform an additional test, and displaying interfaces associated with a progress level, a necessary time, etc. of the additional test on a display unit when the additional test is performed, thereby enabling a user to visibly recognize information associated with a performing process of each test. The test instrument includes: a detection unit configured to apply light to at least one chamber in which a reaction between a reagent and a sample occurs and to detect an optical signal from the chamber to test the sample held in a reaction device, a control unit configured to determine whether to perform a secondary test on the sample after a primary test is performed on the sample and to control to display a secondary test progress interface showing a progress level of the secondary test when the secondary test is performed, and a display unit configured to display a primary test progress interface showing a progress level of the primary test on the sample and to display the secondary test progress interface showing the progress level of the secondary test when the secondary test is performed on the sample. 1. A test instrument comprising:a detection unit configured to apply light to at least one chamber in which a reaction between a reagent and a sample occurs and to detect an optical signal from the chamber to test the sample held in a reaction device;a control unit configured to determine whether to perform a secondary test on the sample after a primary test is performed on the sample and to control to display a secondary test progress interface showing a progress level of the secondary test when the secondary test is performed; anda display unit configured to display a primary test progress interface showing a progress level of the primary test on the sample and to display the secondary test progress ...

Specimen analyzing method and specimen analyzing apparatus

A specimen analyzing method and a specimen analyzing apparatus capable of measuring interference substances before analyzing a specimen. The method comprises a step for sucking the specimen stored in a specimen container ( 150 ) and sampling it in a first container ( 153 ), a step for optically measuring the specimen in the first container, a step for sampling the specimen in a second container ( 154 ) and preparing a specimen for measurement by mixing the specimen with a reagent in the second container, and a step for analyzing the specimen for measurement according to the results of the optical measurement of the specimen.

Automatic analyzer

A display unit displays, on a single screen, a first display area configured from a first area corresponding to the position on a reagent disc at which a reagent container is disposed and a second display area configured from a second area corresponding to the position on a reagent loader at which a reagent container is disposed. A control unit changes the display state of the first area on the basis of whether a reagent container is placed at a position on the reagent disk corresponding to the first area and reagent information for the reagent accommodated in the placed reagent container and changes the display state of the second area on the basis of whether a reagent container is placed at a position on the reagent loader corresponding to the second area and reagent-container-conveyance-state information for the placed reagent container.

PATIENT-BASED RESULTS DISPLAY

A user interface used with a medical testing machine provides improved recall and display of the outcomes of tests performed by the machine. Test outcomes and other information are stored in mass storage directly accessible by the medical testing machine. In one aspect, outcomes of tests relating to a particular patient may be recalled. The system may be especially useful for tests that may be performed multiple times for a particular patient over a period of time, for example testing for HbA1c hemoglobin levels in diabetes patients. The user interface presents a set of screens that allow the display of data according to various filters, and so as to provide detailed information about tests performed by the machine. 1. A user interface for a medical testing machine , the medical testing machine comprising a testing system that performs a medical test on media sampled from patients , each test instance having an outcome , and the medical testing machine storing the test outcomes in a storage system along with other information about each test instance , the user interface comprising:a number of user-selectable tabs at a top of a first displayed user interface screen, the tabs including a first tab that when selected causes to be displayed a second user interface screen with controls for recalling and displaying stored test instance outcomes, and the tab including a second tab that when selected causes to be displayed a third user interface screen that can present information about the performance of a particular test instance;wherein the controls displayed on the second user interface screen include controls for selecting a number of filters to be applied, alone or in combination, to the stored test instance outcomes before display, the filters including a patient ID filter that limits displayed test instance outcomes to those associated with a particular patient number, an accession number filter that limits the displayed test instance outcomes to those associated ...

Facing and Quality Control in Microtomy

The present disclosure also relates to systems and methods for quality control in histology systems. In some embodiments, a method is provided that includes receiving a tissue block comprising a tissue sample embedded in an embedding material, imaging the tissue block to create a first imaging data of the tissue sample in a tissue section on the tissue block, removing the tissue section from the tissue block, the tissue section comprising a part of the tissue sample, imaging the tissue section to create a second imaging data of the tissue sample in the tissue section, and comparing the first imaging data to the second imaging data to confirm correspondence in the tissue sample in the first imaging data and the second imaging data based on one or more quality control parameters. 1. A method for quality control in histology system comprising:receiving a tissue block comprising a tissue sample embedded in an embedding material;imaging the tissue block to create a first imaging data of the tissue sample in a tissue section on the tissue block;removing the tissue section from the tissue block, the tissue section comprising a part of the tissue sample;imaging the tissue section to create a second imaging data of the tissue sample in the tissue section; andcomparing the first imaging data to the second imaging data to confirm correspondence in the tissue sample in the first imaging data and the second imaging data based on one or more quality control parameters.2. The method of claim 1 , wherein the tissue section is non-confirming if there is no correspondence in one or more quality control parameters in the tissue sample in the first imaging data and the second imaging data.3. The method of claim 2 , wherein the one or more quality control parameters include one or more of shape of the tissue sample claim 2 , size of the tissue sample claim 2 , or one or more mechanical damages.4. The method of claim 1 , further comprising transferring claim 1 , using a transfer medium ...

REFLEX TESTING OF SAMPLES USING RESIDUAL MATERIALS FROM A PRIOR TEST

Embodiments disclosed herein relate to methods and systems for performing automated assays, and particularly to performing sequential assays on a sample on an automated instrument. 125-. (canceled)26. A method comprising:receiving, in a dock of an automated instrument, a test strip carrier including a plurality of samples to be tested for target analytes;automatically transferring, via the automated instrument, a first portion of each sample of the plurality of samples to a respective plurality of first vessels comprising first reagents for a first test for a first target analyte;adjusting the automated instrument to automatically perform the first test on the first portion of the plurality of samples according to a first assay workflow, the first test providing a result indicating a presence of the first target analyte in a subset of samples from the plurality of samples;selecting, via the automated instrument, the subset of samples from the plurality of samples;storing, in memory included in the automated instrument, assay-specific data for each of the subset of samples;scanning, via a code reader included in the automated instrument, indicia on test strips associated with the subset of samples;assigning the stored assay-specific data to a respective position in the test strip carrier of each of the test strips associated with the subset of samples based at least in part on the scanned indicia;automatically transferring, via the automated instrument, a second portion of each of the subset of samples to a respective plurality of second vessels comprising second reagents for a second test for a second target analyte, wherein the first target analyte is different than the second target analyte; andautomatically performing, via the automated instrument, the second test on the second portion of each of the subset of samples according to a second assay workflow, the second test providing a result indicating, for an individual sample included in the subset of samples, a ...

Specimen inspection automation system

This specimen inspection automation system is provided with: a processing unit which processes a specimen; a conveying line which conveys carriers; a control device which controls the conveying of the carriers; and external connection modules which deliver the carriers to and from external devices. The control device controls the number of carriers in the specimen inspection automation system within a fixed range on the basis of the number of carriers conveyed into and out of the system by the external connection modules.

SAMPLE TESTING SYSTEM WITH AUTOMATED CONTROL OF SAMPLE RETESTING

A sample testing system comprising: a transporting apparatus; a testing apparatus for obtain a sample and performing testing on the obtained sample; and a controller. The controller executes operation of: controlling the transporting apparatus so as to transport the sample rack in first direction, such that each sample container held in a sample rack is transported to a obtaining position on which the testing apparatus obtains a sample and then the sample rack is transported toward the second position; changing, when retesting of a sample contained in a sample container is necessary, the transporting direction from the first direction to second direction, and then controlling the transporting apparatus so as to transport the sample container accommodating the sample, for which retesting is necessary, to the obtaining position again. Sample testing method and a computer program product are also disclosed. 1. A sample testing method comprising:transporting, from an input buffer, a sample rack including a plurality of holders, wherein each of the plurality of holders is configured to hold a sample container;reading a label attached to the sample container;after the label is read, transporting the sample rack to a sample handling position where the sample container is provided to test a sample contained in the sample container;aspirating and testing the sample contained in the sample container held at each of the plurality of holders;after the sample contained in the sample container held at a last holder of the plurality of holders is aspirated, transporting the sample rack to a parking position; andretesting the sample before the sample rack is transported to the parking position if the sample is contained in at least one sample container held at the holders other than the last holder, and retesting the sample after the sample rack is transported to the parking position and then transported to the sample handling position if the sample is contained in the sample ...

AUTOMATIC ANALYZER

The automatic analyzer includes: a liquid dispensing mechanism that performs suction of a liquid; a pressure sensor that measures a change of an internal pressure of a probe provided at the liquid dispensing mechanism; a determination section that determines whether the suction of the liquid by the probe is normal suction or air suction abnormality; an analysis section; a storage section that stores a cumulative number of times of air suction abnormality per liquid and an allowable cumulative number for the cumulative number of times of air suction abnormality; and a controller that exercises operation control over the liquid dispensing mechanism, the determination section, and the analysis section. The controller exercises control such that the cumulative number of times of air suction abnormality is updated and the updated cumulative number is stored in the storage section even if the air suction abnormality occurs non-consecutively. 1. An automatic analyzer comprising:a liquid dispensing mechanism that sucks a sample or a reagent that is a liquid contained in a container;a pressure sensor that measures a change of a pressure in a probe provided at the liquid dispensing mechanism;a determination section that determines whether suction by the probe is liquid suction that is normal suction or air suction that is abnormal suction on the basis of the change of the pressure measured by the pressure sensor;an analysis section that analyzes the sample;a storage section that stores a cumulative number of air suction abnormalities per liquid determined by the determination section and an allowable cumulative number for the number of the air suction abnormalities, the allowable cumulative number being equal to or greater than 2; anda controller that controls the liquid dispensing mechanism, the determination section, and the analysis section to operate, whereinthe controllerupdates the cumulative number of the air suction abnormalities and stores the updated cumulative ...

Automated Analysis Device

This automated analysis device is provided with a plurality of analysis units for analyzing a specimen, a buffer portion which holds a plurality of specimen racks on which are placed specimen containers holding the specimen, a sampler portion which conveys the specimen racks held in the buffer portion to the analysis units, and a control portion which, when performing a process to deliver the specimen racks to the plurality of analysis units, outputs synchronization signals to all the plurality of analysis units, wherein the analysis unit performs a delivery process starting from the synchronization signal, and the analysis unit performs a delivery process starting from the synchronization signal. 112.-. (canceled)13. An automated analysis device that analyzes specimens , the automated analysis device comprising:a plurality of analysis units that analyze the specimens;a specimen container buffer portion that holds a plurality of specimen containers holding the specimens;a conveyance device that delivers the specimen containers held in the specimen container buffer portion to the analysis units; anda control portion that, when the specimen containers are delivered to the plurality of analysis units, outputs synchronization signals to all of the plurality of analysis units at different timings regardless of whether there is an input of a delivery request from the analysis units during one operation cycle of the conveyance device, whereinthe analysis units deliver the specimen containers starting from the synchronization signals when a delivery request of the specimen containers is output.14. The automated analysis device according to claim 13 , whereinthe conveyance device is operated in the same cycle as an analysis unit having a shortest analysis cycle among the plurality of analysis units that are separately connected to the conveyance device.15. The automated analysis device according to claim 14 , whereinthe control portion spaces output timings of the ...

METHODS, APPARATUS, AND QUALITY CHECK MODULES FOR DETECTING HEMOLYSIS, ICTERUS, LIPEMIA, OR NORMALITY OF A SPECIMEN

A method of characterizing a specimen for HILN (H, I, and/or L, or N). The method includes capturing images of the specimen at multiple different viewpoints, processing the images to provide segmentation information for each viewpoint, generating a semantic map from the segmentation information, selecting a synthetic viewpoint, identifying front view semantic data and back view semantic data for the synthetic viewpoint, and determining HILN of the serum or plasma portion based on the front view semantic data with an HILN classifier, while taking into account back view semantic data. Testing apparatus and quality check modules adapted to carry out the method are described, as are other aspects. 1. A method of characterizing a specimen for HILN , comprising:capturing one or more images from multiple viewpoints of a specimen container including a serum or plasma portion, wherein the specimen container is held in a holder and some portion of the specimen container includes a label;processing the one or more images from the multiple viewpoints to provide segmentation information for each of the multiple viewpoints by determining classifications of regions for each of the multiple viewpoints;generating a semantic map from the segmentation information from each of the multiple viewpoints;selecting a synthetic viewpoint that has visibility of the serum or plasma portion;identifying front view semantic data and back view semantic data for the synthetic viewpoint; anddetermining HILN of the serum or plasma portion based on the front view semantic data with an HILN classifier, while taking into account the back view semantic data.2. The method of claim 1 , wherein the back view semantic data includes information on regions that are classified as being label.3. The method of claim 1 , wherein the back view semantic data includes information on regions that are classified as being holder.4. The method of claim 1 , wherein the back view semantic data includes information on ...

SYSTEMS AND APPARATUS WITH FALLEN CONTAINER DETECTION

Systems and apparatus with circuits that are configured to detect fallen containers upstream or proximate an intake zone suitable for automated evaluation apparatus using different sensors, including at least one lower sensor and at least one upper sensor which is positioned to project an optical signal at a height corresponding to a top portion of an upright container to thereby allow an increased reliability in detection of different orientations and positions of fallen containers. An optional second lower sensor may be used which is longitudinally spaced apart from the first lower sensor and the lower sensors can transmit optical signals across the container travel path that do not intersect. 1. An automated misfeed and/or fallen container detection system comprising:a conveyor providing a travel path for groups of elongated containers;a rotating wheel in cooperating alignment with the conveyor, the wheel having a plurality of circumferentially spaced apart pockets, each pocket configured to accept a single upright elongated container; anda plurality of spaced apart sensors including (i) at least one lower sensor configured to transmit a respective optical signal across the container travel path proximate the wheel at a height that is less than a width dimension of the containers, the at least one lower sensor including a first lower sensor that transmits a respective first optical signal across a front edge portion of a pocket of the wheel facing the conveyor at a loading position and (ii) at least one upper sensor that is positioned proximate the wheel configured to transmit an optical signal at a height corresponding to a top portion of an upright container to thereby allow detection of different orientations and positions of fallen containers and/or container jam or blockage conditions.2. The system of claim 1 , wherein the at least one lower sensor comprises a first lower sensor and a second lower sensor claim 1 , the second lower sensor positioned ...

AUTOMATED MICROBIAL DETECTION APPARATUS

A method and automated apparatus for rapid non-invasive detection of a microbial agent in a test sample is described herein. The apparatus may include one or more means for automated loading, automated transfer and/or automated unloading of a specimen container. The apparatus also includes a detection system for receiving a detection container, e.g., container or vial, containing a biological sample and culture media. The detection system may also include one or more heated sources, holding structures or racks, and/or a detection unit for monitoring and/or interrogating the specimen container to detect whether the container is positive for the presence of a microbial agent therein. In other embodiment, the automated instrument may include one or more, bar code readers, scanners, cameras, and/or weighing stations to aid in scanning, reading, imaging and weighing of specimen containers within the system. 1. An automated detection apparatus for rapid non-invasive detection of microorganism growth in a test sample , comprising:(a) a housing enclosing an interior chamber;(b) a holding structure contained within said interior chamber and comprising a plurality of wells for holding one or more specimen containers;(c) a container locator device comprising a rotatable disk containing one or more locator wells each capable of holding one of said specimen containers, said rotatable disk configured to rotate in a horizontal plane about a vertical axis and thereby locate said specimen containers among one or more container work-flow stations;(d) an automated loading mechanism for automated loading of said specimen container into said interior chamber, said automated loading mechanism comprising a conveyor belt, said conveyor belt configured to place one of said specimen containers into one of said locator wells; and(e) an automated transfer mechanism located within said interior chamber configured for the automated transfer of said specimen container within said interior chamber ...

LABORATORY ANALYSIS SYSTEM WITH IMPROVED SAMPLE PIPETTING

The invention lies in the field of laboratory automation and relates to a laboratory analysis system , in which a plurality of analysis devices and an image recording station are connected to a transportation apparatus for sample vessels and in which sample-vessel-specific information items, which are established in the image recording station , are used for controlling the pipetting apparatuses in the analysis devices 1100. A laboratory analysis system () , comprising{'b': 1', '1', '20', '3', '12, 'a. a multiplicity of analysis devices (), wherein each analysis device () has a control unit (), at least one pipetting apparatus () with a vertically displaceable pipetting needle for taking a sample liquid volume from a sample vessel and at least one analysis apparatus () for analyzing a sample liquid;'}{'b': '101', 'b. an image recording station () for recording images of sample vessels filled with sample liquid, and an associated image evaluation apparatus; and'}{'b': 102', '1', '101, 'claim-text': [{'b': 100', '20', '1', '20', '1, 'characterized in that the laboratory analysis system () further comprises a data transmission apparatus, by means of which sample-vessel-specific information items are transferable from the image evaluation apparatus to the control unit () of at least one analysis device () and wherein the control unit () of the at least one analysis device (), to which the sample-vessel-specific information items are transferable from the image evaluation apparatus, is configured in such a way that it controls a method including the following steps, {'b': '3', 'evaluating the sample-vessel-specific information items from the image evaluation apparatus and establishing one or more sample-vessel-specific parameters for the operation of the pipetting apparatus () when taking a sample liquid volume from a specific sample vessel, and'}, {'b': '1', 'controlling the operation of the pipetting apparatus () when taking a sample liquid volume from a specific ...

Apparatus for Supplying Reagents to a Flow Cytometry System

The disclosure provides example rinse station apparatus, cartridges, and methods for flow cytometry. The rinse station apparatus includes: (a) a cartridge docking station having a base with a recessed receptacle for a cartridge, a vertical support coupled to the base's first end and a top support coupled to the vertical support and cantilevered over the base, the top support has an opening that aligns with the cartridge's opening, (b) a locking arm coupled to the base's second end, the locking arm's free end has a ridge to cooperate with a detent coupled to the cartridge's rear wall to retain the cartridge in place, (c) a spring coupled to the vertical support's front face to apply force to the cartridge's front wall to bias the cartridge toward the locking arm, and (d) a load cell coupled to the base of the cartridge docking station, the load cell measure's the cartridge's weight. 1. A rinse station apparatus for flow cytometry , comprising:at least one cartridge docking station having a base with a recessed receptacle configured to receive a cartridge, a vertical support coupled to a first end of the base and a top support coupled to the vertical support and cantilevered over the base, wherein the top support has an opening arranged therethrough that is configured to align with an opening in the cartridge;a locking arm coupled to a second end of the base, a free end of the locking arm has a ridge configured to cooperate with a detent coupled to a rear wall of the cartridge to retain the cartridge in place on the at least one cartridge docking station;a spring coupled to a front face of the vertical support and configured to apply force to a front wall of the cartridge to bias the cartridge toward the locking arm; andat least one load cell coupled to the base of the at least one cartridge docking station, wherein the load cell is configured to measure a weight of the cartridge.2. The rinse station apparatus of claim 1 , wherein a surface of the recessed receptacle ...

Automatic analyzer

具有检测小体积样品的装置的分析系统

测定测试单元并能够判定是否有足量的样本液体被均匀施加到施加区的分析系统，在本发明的第一实施方案中包括两个光源，它们照明测试条的施加区或测定区的分离照明区域或不完全重叠的照明区域，控制单元，分别激活所述两个光源。一个传感器，它检测由测定区反射或透射的光信号，并产生比例于光强的输出信号，以及测定单元，它在第一光源被激活时，从传感器接收第一输出信号并把它转换为第一测量值，在第二光源被激活时，从传感器接收第二输出信号并把它转换为第二测量值，并比较测量值，然后判定第一测量值与第二测量值间的偏差是否足够小。在根据本发明的分析系统的第二实施方案中，有一个光源用于照明测试单元的样本施加区或测定单元的测定区，两个传感器用于检测测定区反射或透射的光线。传感器的输出信号由测定单元转换为测量值，测定单元判定测量值的偏差是否足够小。

Automatic sample analysis method and apparatus

检体收纳装置、检体处理系统及它们的控制方法

现有检体收纳装置，当对收纳检体有再检查请求时，操作员从收纳的检体中检索相应检体，为了再检查需要再次投入装置，需要工夫和时间。本发明的检体收纳装置具有，检体运送线，用于运送预处理完成的架设在检体运送用支架上的检体；升降机构，可对架设检体的检体托盘进行前后以及上下方向上的驱动；检体夹具机构，将检体从检体运送线的检体取得位置移载到升降机构上的检体托盘中；检体收纳部，从升降机构接收检体托盘，在上下方向上阶层状地具有检体收纳空间，在左右方向上可以保冷地收纳多个检体托盘；闸门机构，在升降机构与检体收纳部进行检体托盘交接时开闭；控制部，控制所述各机构。

Automatic device for microbe detection

FIELD: instrumentation. SUBSTANCE: offered group of inventions relates to devices for fast noninvasive detection of the microbial agent in the tested sample. The device providing the detection of a microbial agent contains a sealed container for samples with an internal cavity with the cultural medium for cultivation of any microorganisms placed in it which can be contained in the tested sample; the housing enclosing the internal chamber; a storage located in the internal chamber and containing a set of cells for placement of one or more containers for samples; a positioning unit of the container with the rotating disk fitted with one or more positioning sockets each of which is capable to hold one of the named containers for samples, and the named rotating disk is implemented with a possibility of rotation in the horizontal plane around a vertical axis and placement of the named containers for samples between one or more operational sections; the automatic loading mechanism for automated loading of the named container for samples into the internal chamber containing the conveyor tape implemented with a possibility of installation of one of the named containers for samples into one of the named positioning sockets; the automatic transfer mechanism installed in the internal chamber for automated transfer of the container for samples within the internal chamber and the detection unit installed in the internal chamber for detection of growth of microorganisms in the container for samples. The named device implements the respective method of detection of growth of microorganisms. EFFECT: offered group of inventions allows to shorten the time and to automate completely the process of analysis of samples for content in them of microbial agents. 14 cl, 30 dwg РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (51) МПК G01N 35/04 (13) 2 559 909 C2 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ОПИСАНИЕ (21)(22) Заявка: ИЗОБРЕТЕНИЯ К ПАТЕНТУ 2011145539/28, 14.05.2010 (24 ...

Analytical system with very small sample detection means

충분한 양의 샘플액체가 사용영역에 고르게 사용되었는지의 여부를 결정하는 수단을 갖는 시험편 평가용 분석 시스템은, 본 발명의 제1실시예에 있어서, 시험편의 사용영역이나 또는 평가영역의 부위를 독립적으로 또는 하나가 완전히 덮히지 않도록 조명하는 두 개 이상의 광원과, 두 개 이상의 광원을 독립적으로 작동시킬 수 있는 제어장치와, 평가영역에 의해 반사되거나 또는 평가영역을 통해 전달된 빛을 검출하여 빛의 세기에 비례하는 출력신호를 발생시키는 하나 이상의 센서와, 광원 중 제1광원이 작동된 경우에는 센서의 제1출력신호를 받아 이를 제1측정값으로 전환하고, 광원 중 제2광원이 작동된 경우에는 센서의 제2출력신호를 받아 이를 제2측정값으로 전환하며, 측정값들을 비교하여 제2측정값으로부터 제1측정값의 편차가 충분히 작은지의 여부를 결정하는 평가장치를 포함한다. 본 발명에 따른 분석장치의 제2실시예에 있어서, 센서의 출력신호는 측정값들의 편차가 충분히 작은지의 여부를 결정하는 평가장치에 의해 측정값들로 전환되기 때문에, 하나 이상의 광원은 시험편의 샘플사용영역이나 또는 평가영역을 조명하는데 사용되고, 두 개 이상의 센서는 평가영역에 의해 반사되거나 또는 전달된 빛을 검출한다.

Automated transfer mechanism for microbial detection apparatus

本发明涉及用于微生物检测设备的自动化传递机构。本发明涉及用于使容器在设备内传递的方法和自动化传递工具。本发明的设备可以包括用于容器(例如试样容器)的自动化加载的工具、用于容器的自动化传递的工具和/或用于容器的自动化卸载的工具。在一个实施方案中，该设备可以是用于对测试样品中的微生物剂进行快速的非侵入的检测的自动化检测设备。检测系统还包括被加热的包围物、保持工具或机架、和/或用于监测和/或询问试样容器以检测容器是否对于微生物剂的存在是阳性的检测单元。在其他实施方案中，自动化仪器可以包括一个或多个的条形码读取器、扫描器、照相机和/或称重站，以辅助对系统内的试样容器的扫描、读取、成像和称重。

Methods and devices for performing analysis of a nucleic acid sample

An automated instrument and method for nucleic acid analysis is provided. The automated instrument is an integrated system including a sample processing station, a first reaction module, a second reaction module, a detection module and a control module for performing homogenous screening of broad specificity and multi-detection reactions on a nucleic acid test sample. The nucleic acid analysis performed in the instrument includes the steps of conducting a first test reaction using a low detection format, and if necessary, a selected second test reaction using a high detection format, detecting signals generated from the test reactions and processing signal data in a control module.

Automatic analyzer

Apparatus for inspecting elements on transport device

트레이 매퍼는 헤드 짐벌 조립체 서스펜션이 적재 트레이의 각각의 이용 가능한 위치에 배치되어 있는가를 검출하기 위해 광학 감지 어레이를 사용한다. 검출할 각 트레이를 트레이 매퍼상에 설치하고 스캐닝 위치에 배치한다. 한 쌍의 전기 기계식 스위치는 다음의 트레이를 처리할 준비가 된 것을 나타내는 신호를 마이크로프로세서에 전송한다. 트레이 매퍼상에 장착된 바 코드 판독기는 트레이상의 라벨을 판독하여 중앙 데이터베이스로부터 트레이에 관한 정보 및 그의 내용을 억세스한다. 트레이 라벨을 판독한 후에, 트레이의 각 위치 밑에 배치된 광 센서가 부품의 존재 또는 부재를 검출한다. 마이크로프로세서는 트레이 라벨과 관련된 값에 대해 각각의 센서의 상태를 판독한다. 오퍼레이터의 데이터 터미널 소프트웨어에 의해 이러한 정보를 사용하여 트레이를 받아들여야 하는지 거부하여야 하는지를 결정한다. 오퍼레이터는 그 터미널상의 텍스트 메시지를 통해 적절한 작동을 알린다. 그 다음, 오퍼레이터는 트레이를 그에 따라 처리한다. The tray mapper uses an optical sensing array to detect whether the head gimbal assembly suspension is disposed at each available position of the loading tray. Each tray to be detected is placed on a tray mapper and placed in a scanning position. The pair of electromechanical switches send a signal to the microprocessor indicating that the next tray is ready for processing. The bar code reader mounted on the tray mapper reads the label on the tray to access information about the tray and its contents from the central database. After reading the tray label, an optical sensor disposed below each position of the tray detects the presence or absence of the part. The microprocessor reads the status of each sensor for the value associated with the tray label. This information is used by the operator's data terminal software to determine whether the tray should be accepted or rejected. The operator informs the user of the proper operation through a text message on the terminal. The operator then processes the tray accordingly.

Automatic analyzer

In an automatic analyzer which includes a reaction container which contains reaction solution therein, a light source which emit light to be transmitted through the reaction solution, a spectral detector which measures the light transmitted through the reaction solution, a memory which stores light measurement data measured by the spectral detector and a CPU which calculates the light measurement data stored in the memory to obtain a light intensity, wherein the spectral detector measures the light over an entirety of an area from one end to the other end of the reaction container at a portion where the reaction solution reserves, the memory stores the light measurement data measured by the spectral detector, and light measurement data in an area where the reaction solution exists is obtained from the memory to calculate a light intensity.

Automatic analyzer and automatic analysis method

Sample analysis system

Automated loading mechanism for microbial detection apparatus

本发明涉及用于微生物检测设备的自动化加载机构。本发明涉及用于加载设备的方法和自动化加载机构。本发明的设备可以包括用于容器(例如试样容器)的自动化加载的工具、用于容器的自动化传递的工具和/或用于容器的自动化卸载的工具。在一个实施方案中，该设备可以是用于对测试样品中的微生物剂进行快速的非侵入的检测的自动化检测设备。检测系统还包括被加热的包围物、保持工具或机架、和/或用于监测和/或询问试样容器以检测容器是否对于微生物剂的存在是阳性的检测单元。在其他实施方案中，自动化仪器可以包括一个或多个的条形码读取器、扫描器、照相机和/或称重站，以辅助对系统内的试样容器的扫描、读取、成像和称重。

Slide management system

An apparatus including a first and a second imaging module; a storage module; an automated transport module operable to transport at least one slide; and a controller operable to direct transport of the at least one slide by the transport module into the first imaging module and into the second imaging module. A method and a machine-readable medium including program instructions to cause a controller to perform a method including transporting at least one slide to a first imaging module using an automated transport module; capturing by the first imaging module of an image of a specimen on the at least one slide; transporting the at least one slide to a storage module using the automated transport module; and transporting the at least one slide to a second imaging module in response to a request for capturing an image in addition to the image captured by the first imaging module.

Method and apparatus for automated assay of biological specimens

An apparatus and method for automated assay of biological specimens positioned on microscope slides. The apparatus comprises an interactive optical subsystem for viewing the biological specimen on the slide and for producing an interactive video signal corresponding to the viewed image. An automated optical subsystem includes a single high power microscope objective for scanning a rack of slides, portions of which having been previously identified for assay in the interactive optical means. The system also includes a processor for processing the interactive and automatic video signals for the two optical subsystems. The processor receives the automatic video signal and performs biological assay functions upon it. A method and apparatus are also disclosed for marking points for later analysis on the microscope slides and for associating an analysis function with each marked point.

Automatic analyzer

Automated cytological sample classification

An automated method for classifying a cytological sample is provided. The method comprises interrogating the sample with one or more wavelengths of light to obtain a result, and then attaching one or more designators to the sample based on whether the result meets a given criterion. The method allows for rapid feedback on the characteristics of the sample, permitting automated designation of the sample as positive for a given characteristic, and allowing for immediate remedial actions if the sample fails to meet the criterion.

Specimen transfer system and sample transfer method

Automatic sample introduction device

一种自动进样装置，包括进给通道、装载区、缓存区和中转调度机构进给通道沿第一方向设置，用于承载和供样本架沿其长度方向上在所述进给通道上移动，进给通道还设置有处理位；装载区与所述进给通道连通，用于承载长度方向沿第一方向的样本架，并供样本架沿第二方向移向进给通道后沿第一方向移动；缓存区用于承载吸样结束等待测试结果的样本架；中转调度机构用于从进给通道接收吸样结束的样本架并调度到缓存区以等待测试结果，当样本需要复检时，将缓存区内对应的样本架从缓存区中移出以使样本架能够移入进给通道。本申请的自动进样装置结构紧凑，可以实现常规进样和快速的复检；并且自动进样装置可以与分析设备独立。

Clinical laboratory analyzer, clinical laboratory analysis method, and program for causing computer to execute the method

DEVICE WITH A LOT OF STANDS FOR PLACING CASES WITH BIOLOGICAL PRODUCTS UNLOADING FROM STORAGE FOR STORING THE MENTIONED TANKS RELATED TO A LABORATORY AUTOMATED SYSTEM

1. Устройство (1) с множеством штативов для размещения емкостей (2) с биологическим продуктом, выгружаемых из хранилища (3) для хранения упомянутых емкостей, соединенное с лабораторной автоматизированной системой (4), отличающееся тем, что оно содержит нечетное количество упомянутых штативов (7), которые могут быть размещены в пределах платформы (6), содержащей множество участков (12, 120), количество которых равно упомянутому нечетному количеству плюс один, причем упомянутые штативы (7) выполнены с возможностью горизонтального или вертикального перемещения с одного участка (12, 120) на другой участок упомянутой платформы (6), пользуясь наличием временно незанятого участка (12, 120), при этом упомянутые штативы (7) по очереди занимают рабочий участок (120), на котором, будучи вертикально расположенным по отношению к выпускной трубе (5) упомянутого хранилища (3), размещаются упомянутые емкости (2) с биологическим продуктом, выгружаемые из упомянутого хранилища (3).2. Устройство (1) по п. 1, отличающееся тем, что каждый из упомянутых штативов (7) располагается на платформе (8), размеры которой выполнены так, что совокупность упомянутых платформ (8) точно соответствует поверхности упомянутой платформы (6) за вычетом упомянутого временно незанятого участка (12, 120).3. Устройство (1) по п. 2, отличающееся тем, что упомянутая платформа (8) содержит фиксаторы (9) на верхнем основании, для того чтобы удерживать упомянутые штативы (7), и колеса (10) на нижнем основании, для того чтобы способствовать ее скольжению по упомянутым участкам (12, 120) упомянутой платформы (6).4. Устройство (1) по п. 1 или 2, отличающееся тем, что перемещение одного или нескольких штативов (7) с одного участка (12, 120) на другой упомянутой платформы (6) осуществляется посредством РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 2015 102 148 A (51) МПК A61J 1/00 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ЗАЯВКА НА ИЗОБРЕТЕНИЕ (21)(22) Заявка: 2015102148, 20.06.2013 (71) Заявитель(и ...

Sample housing device, sample processing system, and method for controlling same

现有检体收纳装置，当对收纳检体有再检查请求时，操作员从收纳的检体中检索相应检体，为了再检查需要再次投入装置，需要工夫和时间。本发明的检体收纳装置具有，检体运送线，用于运送预处理完成的架设在检体运送用支架上的检体；升降机构，可对架设检体的检体托盘进行前后以及上下方向上的驱动；检体夹具机构，将检体从检体运送线的检体取得位置移载到升降机构上的检体托盘中；检体收纳部，从升降机构接收检体托盘，在上下方向上阶层状地具有检体收纳空间，在左右方向上可以保冷地收纳多个检体托盘；闸门机构，在升降机构与检体收纳部进行检体托盘交接时开闭；控制部，控制所述各机构。

Automatic analyzer and specimen test automation system

Water analyzer.

Method and devices for performing analysis of nucleic acid sample

An automated instrument and method for nucleic acid analysis is provided. The automated instrument is an integrated system including a sample processing station, a first reaction module, a second reaction module, a detection module and a control module for performing homogenous screening of broad specificity and multi-detection reactions on a nucleic acid test sample. The nucleic acid analysis performed in the instrument includes the steps of conducting a first test reaction using a low detection format, and if necessary, a selected second test reaction using a high detection format, detecting signals generated from the test reactions and processing signal data in a control module.

Water analyser

The present invention relates to a novel water analyser, making it possible to use the Karl Fischer method to analyse samples containing 10 ppm to 100 ppm of water. This water analyser comprises two analysis loops, one having a volume 20 to 100 times greater than the other, the liquid to be analysed being passed first through the small loop then, if necessary, through the second loop.

METHOD FOR DETECTING THE PRESENCE OF A LIQUID IN A MIXTURE

L'invention concerne un procédé de détection de présence d'un liquide introduit dans un mélange de constituants. Le procédé comprend les étapes suivantes : - excitation (2) du mélange par un signal lumineux en l'absence du liquide à détecter,- mesure (3) d'un signal de fluorescence pendant une durée DELTAt caractéristique du liquide à détecter, de façon à constituer (4) une grandeur de référence Ro,- introduction (5) d'une quantité de liquide à détecter dans le mélange,- excitation (6) du mélange par un signal lumineux,- mesure (7) d'un signal de fluorescence pendant une durée DELTAt de façon à constituer (8) une grandeur R,- comparaison (9) de la grandeur R à une quantité k x Ro. L'invention s'applique à la détection de défaut de pipetage de sérum dans le cadre de bio-essais, notamment de tests immunologiques.

DEVICE FOR SUPPLYING TOTAL BLOOD ANALYZERS

Automatic analyzer

An automatic analyzer includes a sample introduction section, a conveying section, and a plurality of analysis units. In this automatic analyzer, when one or more analysis units suffer failures, it is possible to set the aforementioned analysis units to a power-off enable mode from the screen of an operation section. The analysis unit that has been set to the power-off enable mode becomes separated from the analyzer system operation and the information network in the analyzer system, whereby an analysis operation of the entire analyzer system is allowed to be continued, with the individual power source for the above-described analysis unit turned off.

Synthetic apparatus for inspection of blood

A blood analyzer system transports blood samples through at least one blood analyzer and an automatic blood smear generator under the control of a preprogrammable controller. Blood samples are stored in containers that identify the blood samples they contain. The containers move through the system mounted in protective racks that permit the reading of the identifications. The results of analysis by one or more blood analyzers in the system determines for each sample individually whether or not to make a blood smear. When a blood smear is to be made, the controller makes the smear thickness of each blood sample consistent with other samples whatever the consistency of the sample to be smeared. If a required sample is not made, a detector sounds an alarm, thereby alerting operators that the system has failed.

Automatic apparatus for analysis of blood

Automatic analysis instrument

(57)【要約】本公報は電子出願前の出願データであるた め要約のデータは記録されません。

Sample analyzer and sample analyzing method

Herewith disclosed is a sample analyzer comprising: a measurement section configured to perform a measurement on a sample and generate a measurement value according to the concentration of an analyte in the sample; a memory storing a calibration curve; an analysis section; an output section; and an instruction receiver. When the instruction receiver receives an instruction to perform a diluting measurement on a calibration sample, the measurement section dilutes the calibration sample by a predetermined ratio and performs a measurement on the diluted calibration sample, and the analysis section determines the concentration of the analyte in the diluted calibration sample by applying a measurement value obtained from the diluted calibration sample to the calibration curve. Information generated based on the determined concentration and the known concentration is output.

Automatic analysis device and detection method for measurement value abnormalities

There is provided an automatic analyzer for detecting measurement value abnormalities stemming from reaction process anomalies caused by the presence of foreign matter or bubbles without recourse to complicated processing or functionality of the analyzer. Checks for measurement value abnormalities are started to determine whether the results of concentration calculation based on light quantity data from multiple target detectors each fall within an applicable determination range (steps a, b). If the results of concentration calculation are found to fall within the determination range, an average value of the results of concentration calculation with the target detectors is calculated. If the results of concentration calculation are found to fall outside the determination range, an out-of-determination-range flag is given, and an average value of the results of concentration calculation with the target detectors is calculated (steps c, d). A default fluctuation range is retrieved regarding the average value of the results of concentration calculation. The fluctuation range of the results of concentration calculation with the multiple target detectors is calculated. It is then determined whether the calculated fluctuation range falls within the default range (steps e, f, g). If the fluctuation range is found to fall within the default range, the results of concentration calculation are output to a display unit; if the fluctuation range is found to fall outside the default range, the display unit is caused to display a reexamination request and add a measurement value abnormality alarm (steps h, i, j).

Blood cell analyzer, blood cell analyzing method, and non-transitory storage medium

Tube characterization station

Systems and methods for use in an in vitro diagnostics setting may include an automation track, a plurality of carriers configured to carry a plurality of sample vessels along the automation track, and a characterization station including a plurality of optical devices. A processor, in communication with the characterization station, can be configured to analyze images to automatically characterize physical attributes related to each carrier and/or sample vessel. A method may include receiving a plurality of images from a plurality of optical devices of a characterization station, wherein the plurality of images comprise images from a plurality of perspectives of a sample vessel being transported by a carrier, automatically analyzing the plurality of images, using a processor, to determine certain characteristics of the sample vessel, and automatically associating the characteristics of the sample vessel with the carrier in a database.

Procedure for classifying color images of serum samples from centrifuged body fluids

Procedimiento para la clasificación de imágenes a color de suero de líquidos corporales centrifugados, donde - se toman imágenes a color de suero de muestras de suero de líquidos corporales centrifugados, - se clasifican las muestras de suero como, "buenas", "hemolíticas", "lipémicas" o "ictéricas" para la elaboración deuna muestra de aprendizaje clasificada, donde la muestra de aprendizaje clasificada comprende datos de lasimágenes a color y su respectiva clasificación, - se entrena un clasificador mediante la muestra de aprendizaje clasificada, - se realiza al menos una fotografía a color del suero de un líquido corporal centrifugado (21) situado en unrecipiente (20) mediante un dispositivo de grabación de imágenes (30) y - se clasifica como "bueno", "hemolítico", "lipémico" o "ictérico" el suero de la fotografía en color del líquido corporalcentrifugado por medio del clasificador, mediante el software de procesamiento de imágenes. Procedure for the classification of serum color images of centrifuged body fluids, where - serum color images are taken from samples of centrifuged body fluids, - serum samples are classified as "good", "hemolytic", "lipemic" or "icteric" for the elaboration of a classified learning sample, where the classified learning sample comprises data of the color images and their respective classification, - a classifier is trained by means of the classified learning sample, - at least a color photograph of the serum of a centrifuged body liquid (21) located in a vessel (20) by means of an image recording device (30) and - is classified as "good", "hemolytic", "lipemic" or "icteric" the color photography serum of the body fluid centrifuged by means of the classifier, using the image processing software.

Handling method of body fluid sample and analysis apparatus using the same

Sample sampling to an analysis apparatus 200 or 820 for analyzing a biochemical analysis item is performed by a pipetting device 202 or 840 which uses a repetitively used pipette nozzle, and sample sampling to an analysis apparatus 100 or 810 for analyzing an immune analysis item is performed by a pipetting device 102 or 830 which uses a disposable nozzle tip. A sample bottle containing a sample to be analyzed on both of a biochemical analysis item and an immune analysis item is sample-pipetted by the nozzle tip first, and then transported so as to be sample-pipetted by the pipette nozzle.

Data processor for automatic analyzing device for blood

(57)【要約】本公報は電子出願前の出願データであるた め要約のデータは記録されません。

Analytical system with means for detecting too small sample volumes

Analytical system for evaluating test elements having means of determining whether a sufficient amount of sample liquid was evenly applied to an application zone comprising in a first embodiment of the invention at least two sources of light which illuminate separate or at least not fully overlapping areas of the application zone or the evaluation zone of the test strip, a control unit with which the light sources, of which there at least two, can be independently activated, at least one sensor which detects light reflected by the evaluation zone or transmitted by the evaluation zone and supplies an output signal proportional to the intensity of light as well as an evaluation unit which receives a first output signal from the sensor and converts it into a first measured value when the first of the light sources is activated, receives a second output signal from the sensor and converts it into a second measured value when the second of the light sources, is activated and compares the measured values and determines whether the deviation of the first value measured from the second value measured is sufficiently small. In a second embodiment of an analytical system according to the invention, at least one light source is used to illuminate the sample application zone or the evaluation zone of a test element and at least two sensors detect light reflected or transmitted by the evaluation zone, the output signal of the sensors being converted into measured values by the evaluation unit which determines whether the deviation of the measured values is sufficiently small.

Handling method of body fluid sample and analysis apparatus using the same

Sample sampling to an analysis apparatus 200 or 820 for analyzing a biochemical analysis item is performed by a pipetting device 202 or 840 which uses a repetitively used pipette nozzle, and sample sampling to an analysis apparatus 100 or 810 for analyzing an immune analysis item is performed by a pipetting device 102 or 830 which uses a disposable nozzle tip. A sample bottle containing a sample to be analyzed on both of a biochemical analysis item and an immune analysis item is sample-pipetted by the nozzle tip first, and then transported so as to be sample-pipetted by the pipette nozzle.

Methods and computer program products for detecting fallen containers

Methods, systems, computer program products, apparatus and circuits are configured to detect fallen containers upstream or proximate an intake zone suitable for automated evaluation apparatus using different sensors, including at least one lower sensor and at least one upper sensor which is positioned to project an optical signal at a height corresponding to a top portion of an upright container to thereby allow an increased reliability in detection of different orientations and positions of fallen containers. An optional second lower sensor may be used which is longitudinally spaced apart from the first lower sensor and the lower sensors can transmit optical signals across the container travel path that do not intersect.

Systems and methods for detecting fallen containers suitable for apparatus for automated evaluation of microorganism growth in test samples

Methods, systems, computer program products, apparatus and circuits are configured to detect fallen containers upstream or proximate an intake zone suitable for automated evaluation apparatus using different sensors, including at least one lower sensor and at least one upper sensor which is positioned to project an optical signal at a height corresponding to a top portion of an upright container to thereby allow an increased reliability in detection of different orientations and positions of fallen containers. An optional second lower sensor may be used which is longitudinally spaced apart from the first lower sensor and the lower sensors can transmit optical signals across the container travel path that do not intersect.

Methods and devices for performing analysis of a nucleic acid sample

Automated loading mechanism for microbial detection apparatus

本发明涉及用于加载设备的方法和自动化加载机构。本发明的设备可以包括用于容器(例如试样容器)的自动化加载的工具、用于容器的自动化传递的工具和/或用于容器的自动化卸载的工具。在一个实施方案中，该设备可以是用于对测试样品中的微生物剂进行快速的非侵入的检测的自动化检测设备。检测系统还包括被加热的包围物、保持工具或机架、和/或用于监测和/或询问试样容器以检测容器是否对于微生物剂的存在是阳性的检测单元。在其他实施方案中，自动化仪器可以包括一个或多个的条形码读取器、扫描器、照相机和/或称重站，以辅助对系统内的试样容器的扫描、读取、成像和称重。

Reflectance inspection of samples using previously inspected residual material

本申请涉及使用先前检验的残余材料反射检验样本。本文中公开的实施方式涉及进行自动测定的方法和系统，并且具体涉及在自动仪器上对样本进行连续测定。

Analysing system with means for detecting insufficient dose

The analysis system for the analysis of test elements (T), comprises means for the detection by which a sufficient quantity of sample fluid is uniformly abandoned in feeding zone of the test elements. The detection means comprises two sensors that detect light reflected or transmitted by an area of the feeding zone or evaluation zone (A) and deliver exit signals corresponding to the light intensity, where the areas are separated from each other or not completely overlap, a light source that illuminates a sample application zone or detection zones, and a detection unit (E). The analysis system for the analysis of test elements (T), comprises means for the detection by which a sufficient quantity of sample fluid is uniformly abandoned in feeding zone of the test elements. The detection means comprises two sensors that detect light reflected or transmitted by an area of the feeding zone or evaluation zone (A) and deliver exit signals corresponding to the light intensity, where the areas are separated from each other or not completely overlap, a light source that illuminates a sample application zone or detection zones, and a detection unit (E) that receives an exit signal of the first and second sensor, converts into first and second measuring value and that compares and assesses the first and the second readings whether the deviation of the readings is sufficiently slight from one another. The deviation of the readings is determined from one another by forming the sum of the difference of the readings and the sum difference is compared with a given limit. The deviation of the readings is determined from one another as a relative deviation and is compared with a given limit. The feeding zone of the test element is covered with a network, which has quadratic or rectangular stitches. The connection line between the areas, from which the sensors receive radiations forms an angle of 45[deg] with the thread of the network.

Additional research of samples with application of residual materials from previous test

FIELD: food industry. SUBSTANCE: in performing the method of the automated analysis of a plurality of specimens, an automated device is provided, made with the possibility to receive and process a plurality of samples from said plurality of specimens to determine one or more predetermined analytes according to one or more corresponding analytical technological processes. The plurality of specimens to be examined is provided. The plurality of specimens is processed to obtain a corresponding plurality of samples. The first portion of each sample from the plurality of samples to be examined is automatically transferred to the corresponding plurality of first vessels containing the reagents for the first test to determine the first specified analyte. The automatic first test is performed on part of said plurality of samples to determine the presence of the first specified analyte according to the first analytical technological process. The subset of samples of the plurality of samples are selected, in which the presence of the first specified analyte was determined. The second part of the subset of previously selected samples is automatically transferred to the second vessel containing the reagents for the second test to determine the presence of the second specified analyte according to the second analytical technological process. The second test is automatically performed on the second part of the selected subset of the samples. The system for performing the automated analysis of the plurality of samples from the corresponding plurality of samples comprises an automated device comprising a plurality of test strips, a processor, a storage of informative capacity, and a program for performing the automated analysis. EFFECT: increased reliability and ease of use while performing the analysis of the plurality of samples on an automated device. 25 cl, 3 dwg, 4 ex РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 2 627 383 C2 (51) МПК G01N 35/04 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ...

Automatic analyzer

An automatic analyzer, capable of obtaining analysis results using reaction liquids with absorbance appropriate for analysis processing, is provided. To that end, the analyzer includes: a standard deviation calculating section for calculating a standard deviation of absorbances of a reaction liquid, measured by a photometry section at any one time a reaction container passes through the photometry section, every time the reaction container passes through the photometry section; a standard deviation judging section for judging whether each standard deviation calculated by the standard deviation calculating section is smaller than a threshold set based on a standard deviation of absorbances of a homogeneously-stirred reaction liquid; and an absorbance determining section for determining any of average values of a plurality of absorbances with a standard deviation judged smaller than the threshold by the standard deviation judging section, calculated by the average value calculating section, as absorbance for sample analysis.

Reflex testing of samples using residual materials from a prior test

Embodiments disclosed herein relate to methods and systems for performing an automated assays, and particularly to performing sequential assays on a sample on an automated instrument.

Hematological analyzer system with removable cartridge

A system relating to sample analyzers, and more particular, to sample analyzers that are simple to operate and have a reduced risk of providing an erroneous result to a user. In some cases, the sample analyzer may be a portable sample analyzer that includes a disposable fluidic cartridge. The operators of the analyzers need not be trained.

slide management system

a presente invenção refere-se a um aparelho que inclui um primeiro e um segundo módulo de formação de imagem; um módulo de armazenamento; um módulo de transporte automatizado operável para transportar pelo menos um slide; e um controlador operável para direcionar o transporte do pelo menos um slide pelo módulo de transporte para dentro do primeiro módulo de formação de imagem e para dentro do segundo módulo de formação de imagem. um método e um meio legível por máquina que inclui instruções de programa para fazer com que um controlador execute um método que inclui transportar pelo menos um slide para um primeiro módulo de formação de imagem utilizando um módulo de transporte automatizado; capturar pelo primeiro módulo de formação de imagem uma imagem de um espécime sobre o pelo menos um slide; transportar o pelo menos um slide para um módulo de armazenamento utilizando o módulo de transporte automatizado; e transportar o pelo menos um slide para um segundo módulo de formação de imagem em resposta a uma solicitação para capturar uma imagem além da imagem capturada pelo primeiro módulo de formação de imagem.

Device with multiple tripods for placement of containers with biological product removed from storage to store these containers, associated with laboratory automation system

FIELD: medicine. SUBSTANCE: laboratory automated system containing a storage for containers with a biological product and a device with multiple tripods for containers with a biological product removed from the said storage. The mentioned device contains an odd number of tripods that can be placed within a platform with multiple sites, the number of which is referred to the said odd number plus one. The said tripods are configured to move horizontally or vertically from one site of the said platform to another using a temporarily unoccupied site. The said tripods in turn occupy a working area in which, when arranged vertically relative to the outlet pipe of the said storage, the said containers are with a biological product removed from the said storage are placed. The storage contains a storage control unit that counts the containers with the product discharged through the discharge pipe to one of the tripods, which in turn occupies the working area, and the storage control unit starts to move the said tripods from one site to another when one of the tripods that in turn, occupies the working area, is filled with a given number of containers with biological material. EFFECT: increased efficiency and reliability of testing. 9 cl, 5 dwg РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 2 645 088 C2 (51) МПК B65G 1/133 (2006.01) A61J 1/14 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ОПИСАНИЕ ИЗОБРЕТЕНИЯ К ПАТЕНТУ (52) СПК B65G 1/133 (2006.01); A61J 1/14 (2006.01) (21)(22) Заявка: 2015102148, 20.06.2013 (24) Дата начала отсчета срока действия патента: (73) Патентообладатель(и): ИНПЕКО ХОЛДИНГ ЛТД. (MT) Дата регистрации: 15.02.2018 R U 20.06.2013 (72) Автор(ы): ПЕДРАЦЦИНИ Джанандреа (CH) (56) Список документов, цитированных в отчете о поиске: US 2010/0303590 A1, 02.12.2010. RU 84381 U1, 10.07.2009. DE 202007002753 U1, 26.04.2007. US 2010/0049358 A1, 25.02.2010. US 6551556 B1, 22.04.2003. 25.06.2012 IT MI2012A001111 (43) Дата публикации заявки: 20.08.2016 Бюл ...

Real time previous values comparison system for clinical inspection system

(57)【要約】本公報は電子出願前の出願データであるた め要約のデータは記録されません。

Tube characterization station

Systems and methods for use in an in vitro diagnostics setting may include an automation track, a plurality of carriers configured to carry a plurality of sample vessels along the automation track, and a characterization station including a plurality of optical devices. A processor, in communication with the characterization station, can be configured to analyze images to automatically characterize physical attributes related to each carrier and/or sample vessel. A method may include receiving a plurality of images from a plurality of optical devices of a characterization station, wherein the plurality of images comprise images from a plurality of perspectives of a sample vessel being transported by a carrier, automatically analyzing the plurality of images, using a processor, to determine certain characteristics of the sample vessel, and automatically associating the characteristics of the sample vessel with the carrier in a database.

Automatic analyzing instrument

(57)【要約】本公報は電子出願前の出願データであるた め要約のデータは記録されません。

Device for Supplying Blood Tubes to a Whole Blood Analyser

A device including a pre-analytical module provided with at least one tube stirrer for homogenizing blood and preventing clot formation and disposed on a line for single-tube transfer between an area for storing analyzable tubes, and at least one unitary operating whole blood analyzer and automatic tube-loading/unloading device arranged between the tube stirrer and the single-tube transfer line. The device is suitable for blood analyzers.

Automatic analysis device and specimen inspection automation system

In order to easily identify a specimen to be extracted because, for example, an item remains uninspected, from a rack 31 collected in a storage part 13 or the rack 31 taken out from the storage part, a camera of a smart device takes an image of the rack; and a calculation unit included in the smart device provides a mark, by AR technology, at the position of a specimen to be extracted. For example, the item that remains uninspected is identified on the basis of information about a combination of a rack ID and an identifier and information, which is received from an operation unit about specimens at respective positions. Thus, irrespective of a place or whether the specimen to be extracted is inside or outside of the device, the specimen to be extracted can be reliably specified from a plurality of specimen containers provided on a holder.

Analysis device, analysis system and analysis method

Provided is technology which can improve the efficiency of analysis as a whole when a plurality of analyses are performed on a sample. An analysis device (A) is provided with: a first analysis unit (A1) for performing a first analysis on a sample; a second analysis unit (A2) for performing a second analysis on a sample; a short-time analysis unit (A3) for performing a short-time analysis on a sample, in which an analysis result can be derived in a shorter period of time than in the first analysis; and a determination unit (63) for determining whether or not to perform the second analysis, in accordance with the result of the short-time analysis and before the result of the first analysis is derived.

Multiple rack apparatus for accommodating biological product containers unloaded from a storage for the preservation of the same interfaced with a laboratory automation system