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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Форма поиска

Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 2093. Отображено 100.
02-02-2012 дата публикации

Holographic microscope

Номер: US20120026313A1
Принадлежит: ROCKEFELLER UNIVERSITY

A holography attachment device for a digital imaging device. The holography attachment device including a chamber having a proximate end configured to attach to the digital imaging device. A distal end of the chamber includes a wall. Also, the chamber includes a sample holder section located between the proximate end and the distal end. The sample holder section is configured to receive a sample. The chamber is configured to attach to the digital imaging device.

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28-03-2013 дата публикации

SCANNER DEVICE AND DEVICE FOR MEASURING THREE-DIMENSIONAL SHAPE OF OBJECT

Номер: US20130076857A1
Принадлежит: Dai Nippon Printing Co., Ltd.

A laser beam is reflected by a light beam scanning device and irradiated onto a hologram recording medium. On the hologram recording medium, an image of a linear scatter body is recorded as a hologram by using reference light that converges on a scanning origin. The light beam scanning device bends the laser beam at the scanning origin and irradiates the laser beam onto the hologram recording medium. At this time, by changing a bending mode of the laser beam with time, an irradiation position of the bent laser beam on the hologram recording medium is changed with time. Diffracted light from the hologram recording medium produces a reproduction image of the linear scatter body on a light receiving surface of the stage. When an object is placed on the light receiving surface, a line pattern is projected by hologram reproduction light, so that the projected image is captured and a three-dimensional shape of the object is measured. 1. A scanner apparatus that scans an object (M) with a line pattern (U) of light and imports surface information of the object (M) , comprising:{'b': 100', '110, 'an illumination unit (, ) that projects the line pattern (U) of light onto the object (M);'}{'b': '200', 'a pattern scanning mechanism () that changes a projection position of the line pattern (U) on the object (M) with time; and'}{'b': 300', '301', '303, 'an imaging unit (, to ) that captures an image of the object (M) onto which the line pattern (U) is projected from a predetermined direction, and imports surface information of the object (M), wherein'}{'b': 100', '110, 'the illumination unit (, ) includes'}{'b': 50', '50, 'a coherent light source () that generates a coherent light beam (L),'}{'b': 45', '46', '85', '35', '30, 'a hologram recording medium (, , ) on which an image () of a scatter body () having a shape corresponding to the line pattern (U) is recorded, and'}{'b': 60', '65', '60', '65', '45', '46', '85', '60', '65', '45', '46', '85, 'a light beam scanning device (, ) ...

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11-04-2013 дата публикации

Digital Holographic Method of Measuring Cellular Activity and Measuring Apparatus with Improved Stabililty

Номер: US20130088568A1
Автор: David D. Nolte
Принадлежит: PURDUE RESEARCH FOUNDATION

Motility contrast imaging (MCI) is a depth-resolved holographic technique to extract cellular and subcellular motion inside tissue. The holographic basis of the measurement technique makes it highly susceptible to mechanical motion. The motility contrast application, in particular, preferably includes increased mechanical stability because the signal is based on time-varying changes caused by cellular motion, which should not be confused with mechanical motion of the system. Apparatus for motility contrast imaging that provides increased mechanical stability is disclosed. It is based on common-path configurations, in which the signal and reference beams share optical elements in their paths to the detector. The two beams share mechanical motions in common, and hence these motions do not contribute to the signal.

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18-04-2013 дата публикации

Digital Holographic Method of Measuring Cellular Activity and of Using Results to Screen Compounds

Номер: US20130096017A1
Автор: David D. Nolte, Kwan Jeong
Принадлежит: PURDUE RESEARCH FOUNDATION

Motility contrast imaging (MCI) is a depth-resolved holographic technique to extract cellular and subcellular motion inside tissue. The holographic basis of the measurement technique makes it highly susceptible to mechanical motion. The motility contrast application, in particular, preferably includes increased mechanical stability because the signal is based on time-varying changes caused by cellular motion, not to be confused with mechanical motion of the system. The use of the resulting spectrogram response signatures, or “fingerprint” data, of known compounds is disclosed to screen new compounds for leads as to those having potentially beneficial mechanisms of action. The “fingerprint” data of known toxic compounds can be used to screen new compounds for toxicity.

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25-04-2013 дата публикации

Holographic Microscope, Microscopic Subject Hologram Image Recording Method, Method of Creation of Hologram for Reproduction of High-Resolution Image, and Method for Reproduction of Image

Номер: US20130100241A1
Автор: Sato Kunihiro
Принадлежит: Hyogo Prefectural Government

An interference fringe pattern (I) between an inline spherical wave light (L) and an off-axis reference light (R) is recorded with a photo detector (), and on which spatial-frequency filtering is applied to obtain a complex amplitude in-line hologram (J). A complex amplitude off-axis hologram (J) is derived by performing a spatial frequency filtering on a hologram (I) in which an object light (O) emitted from a microscopic subject illuminated with a spherical wave light (L) is recorded with a reference light (R), and the derived data is divided with data of the hologram (J) so that a complex amplitude in-line hologram (J) from which a component of the reference light (R) is eliminated is generated and recorded. 1. A holographic microscope , comprising:{'sub': OR', 'OL', 'OR', 'OL, 'b': '2', 'an image recording section which obtains an off-axis hologram (I) of a microscopic subject by illuminating the microscopic subject with a spherical wave light (L or L) as an illumination light, generates a complex amplitude in-line hologram (J) from the off-axis hologram (I), and records the complex amplitude in-line hologram (J); and'}{'sub': 'OL', 'an image reconstruction section which reconstructs an image from the complex amplitude in-line hologram (J) recorded by the image recording section, wherein the image recording section comprisesa light source which emits a coherent light;an optical system which propagates an illumination light, a reference light, and an object light;a photodetector which records light intensity of the reference light and the object light;{'sub': LR', 'LR', 'LR, 'a reference light wave obtaining section which records an interference fringe pattern (I) between an in-line spherical wave light (L) and an off-axis reference light (R), which is made with the light source and the optical system, using the photodetector, and derives a complex amplitude in-line hologram (J) having recorded the off-axis reference light (R) by performing a spatial frequency ...

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13-06-2013 дата публикации

Speckle noise reduction based on longitudinal shift of sample

Номер: US20130148182A1
Принадлежит: Canon Inc

A method and apparatus for reducing speckle noise in an image of an object are disclosed. The method includes, placing the object in an interferometer at a first position along a beam path of an object beam, irradiating the object with the object beam, moving the object from the first position to a second position by longitudinally shifting the object along the beam path of the object beam, irradiating the object with the object beam at the second position. At each of the first and second positions a holographic image formed by interference between the object beam and a reference beam is recorded. An object image with reduced speckle noise is obtained by averaging the holographic images. Either an arithmetic mean or a weighted average may be used in the averaging of the holographic images.

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24-10-2013 дата публикации

Device and Method for Holographic Reflection Imaging

Номер: US20130278981A1
Принадлежит: IMEC

Methods and devices for holographic imaging are disclosed. In some embodiments, a holographic imaging device is disclosed that includes at least one radiation source, a reflective surface, and an image sensor. The at least one radiation source may be configured to emit a radiation wave towards the reflective surface and an object positioned on or near the reflective surface, where the radiation wave is reflected by the reflective surface to produce a reference wave and is reflected directly toward the image sensor by the object to produce an object wave directed at the image sensor. Further, the image sensor may be configured to determine an interference pattern between the reference wave and the object wave. A holographic image representing the object may be reconstructed based on the interference pattern. 1. A holographic imaging device comprising:at least one radiation source;a reflective surface; and (a) the at least one radiation source is configured to emit a radiation wave towards the reflective surface and an object positioned on or near the reflective surface, wherein the radiation wave is reflected by the reflective surface to produce a reference wave and is reflected directly toward the image sensor by the object to produce an object wave directed at the image sensor, and', '(b) the image sensor is configured to determine an interference pattern between the reference wave and the object wave., 'an image sensor, wherein2. The holographic imaging device of claim 1 , wherein the reflective surface is substantially parallel to the image sensor.3. The holographic imaging device of claim 1 , wherein the radiation wave being reflected directly toward the image sensor by the object comprises the radiation wave being reflected directly toward the image sensor by the object without the use of intermediate optical devices.4. The holographic imaging device of claim 1 , wherein the at least one radiation source is positioned between the reflective surface and the ...

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07-11-2013 дата публикации

Miniature microscope and manufacturing method of optical element thereof

Номер: US20130293697A1
Принадлежит: National Chiao Tung University NCTU

A manufacturing method of an optical element applied to a miniature microscope comprises the steps of: emitting a signal light and a reference light to an optical material; and forming a plurality of gratings on the optical material by interfering the signal light and the reference light. A miniature microscope is also disclosed.

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14-11-2013 дата публикации

DIGITAL HOLOGRAPHY DEVICE AND IMAGE GENERATION METHOD USING DIGITAL HOLOGRAPHY

Номер: US20130301093A1

A digital holography device () which is capable of measuring a subject with high accuracy by correcting intensity unevenness by accurately removing zeroth-order diffracted light, includes: a hologram generating section () for generating a first hologram and a second hologram each obtained by extracting components identical in phase shift amount from a polarizer array hologram which is recorded in an image capturing device () mounted with a polarizer array (); a dividing section () for dividing the first hologram into a plurality of first regions, and dividing the second hologram into a plurality of second regions; a comparing section () for comparing a first average value of an intensity in a first region of the first hologram and a second average value of an intensity in a second region of the second hologram which region corresponds to the first region; and a correcting section () for, in a case where the first average value and the second average value differ, correcting at least one of the first average value and the second average value so that the first average value and the second average value are equal. 1. A digital holography device comprising:a hologram generating section for generating a first hologram and a second hologram each obtained by extracting components identical in phase shift amount of a reference light beam from a polarizer array hologram which is recorded in a pixel of an image capturing device mounted with a polarizer array and includes two or more kinds of hologram information that differ in the phase shift amount;a dividing section for dividing the first hologram into a plurality of first regions, and dividing the second hologram into a plurality of second regions in a second pattern identical to a first pattern in which the first hologram is divided into the plurality of first regions;a comparing section for comparing a first average value of an intensity in a first region of the first hologram and a second average value of an intensity ...

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12-12-2013 дата публикации

System with diffused illumination for tomographic imaging

Номер: US20130329226A1

The present invention provides an apparatus for tomographic imaging of an object. The apparatus includes a light unit configured to generate illumination, which comprises coherent light and has random phase distribution in a plane perpendicular to an optical axis, for illuminating an object, a coupler which combines a reference beam and an object beam for an interference, a shifter configured to shift relative phase difference between the object light and the reference coherent light, a detector configured to detect an interference caused by the reference coherent light and object light for the each phase, and a processor configured to calculate an optical propagation based on the detected interference for the each phase.

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19-12-2013 дата публикации

System, apparatus and method for extracting three-dimensional information of an object from received electromagnetic radiation

Номер: US20130335796A1
Автор: Gary Brooker, Joseph Rosen
Принадлежит: Individual

An apparatus and method to produce a hologram of an object includes an electromagnetic radiation assembly configured to receive a received electromagnetic radiation, such as light, from the object. The electromagnetic radiation assembly is further configured to diffract the received electromagnetic radiation and transmit a diffracted electromagnetic radiation. An image capture assembly is configured to capture an image of the diffracted electromagnetic radiation and produce the hologram of the object from the captured image.

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26-12-2013 дата публикации

Method and device for focussing a microscope automatically

Номер: US20130342673A1
Принадлежит: CARL ZEISS AG, CARL ZEISS MICROSCOPY GMBH

A method for automatic focusing of a microscope with a microscope objective on a selected area of a specimen, in which a digital hologram of the selected area of the specimen is generated in an off-axis mode and a microscope with which the method is implemented. The digital hologram is used to determine, on the optical axis of the microscope objective, a focus position to be set in which the selected area of the specimen is optimally in focus. Subsequently, a control system is used to set the microscope to the focus position determined and thus is focused on the area selected.

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05-01-2017 дата публикации

Digital Holographic Device

Номер: US20170003650A1
Принадлежит:

The techniques, apparatus, material and systems are described for a portable camera device which can be attached to the camera port of a conventional transmission or reflection microscope for complex wave front analysis. At least one holographic element (BS, grating) splits the beam (s) containing the sample information in two beams (r,o) and filters (r′, o′) them. The proposed invention has a relaxed alignment sensitivity to displacement of the beam coming from the microscope. Besides since it compensates the coherence plane tilt angle between reference and object arms, it allows for creating high-visibility interference over the entire field of view. The full-field off-axis holograms provide the whole sample information. 125-. (canceled)26. A hologram generating device for generating a hologram from a sample beam formed by collecting electromagnetic radiation coming from an object , the device comprising:a beam generation unit arranged to split the sample beam into an object beam and a reference beam, the object beam being a non-filtered or partially filtered first portion of the sample beam and the reference beam being a partially or completely filtered second portion of the sample beam;a coherence management unit arranged to orientate a coherence plane of at least one of the object beam and the reference beam to render the coherence plane of the object beam and the reference beam substantially parallel; anda hologram creation unit configured to combine the object beam and the reference beam to create the hologram by interference between the reference beam and the object beam.27. The device according to claim 26 , wherein the beam generation unit includes a holographic filtering element configured to split the sample beam and to spatially filter the sample beam to produce an object beam and a reference beam including the filtered split sample beam of spatial intensity uniformity; or includes a splitter to split the sample beam into a first split beam and a second ...

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04-01-2018 дата публикации

Method and system for monitoring a building structure

Номер: US20180003499A1

A system for monitoring a building structure is described. The system comprises a laser source which emits an infrared radiation and an interferometric arrangement which divides the radiation into an object beam and a reference beam. The object beam irradiates the building structure and is scattered by it, while the reference beam interferes with the scattered object beam so as to create a hologram of the building. The system also comprises a sensor which detects a sequence of holograms and a processing unit which reconstructs the evolution in time of deformations or displacements of the building by numerically processing the sequence of holograms. The system—being based on digital holography—offers various advantages compared to known monitoring techniques, for example techniques which make use of seismometers (possibility of remote monitoring, substantial space-time continuity of the monitoring, capacity for detecting a wider range of deformations and displacements).

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04-01-2018 дата публикации

COHERENCE ADJUSTABLE DIGITAL HOLOGRAPHY SYSTEM

Номер: US20180004157A1

Disclosed is a coherence-adjustable digital holography system. More particularly, the coherence-adjustable digital holography system includes a light source part for generating low-interference light; a dispersion part for dispersing the generated light, an adjustment part for adjusting coherence by adjusting a spectrum bandwidth of the light which has passed through the dispersion part; and a detection part for detecting a holographic image of a subject from the adjusted light. In accordance with such a configuration, an interference fringe may be easily obtained through coherence adjustment, whereby the accuracy of a detected holographic image may be improved. 1. A coherence-adjustable digital holography system , comprising:a light source part for generating low-interference light;a dispersion part for dispersing the generated light;an adjustment part for adjusting coherence by adjusting a spectrum bandwidth of the light which has passed through the dispersion part; anda detection part for detecting a holographic image of a subject from the adjusted light.2. The coherence-adjustable digital holography system according to claim 1 , wherein the light source part generates low-interference light having multiple wavelengths excluding a laser.3. The coherence-adjustable digital holography system according to claim 1 , wherein the light source part comprises at least any one of an LED lamp and a halogen lamp.4. The coherence-adjustable digital holography system according to claim 1 , wherein the dispersion part widely disperses a wavelength of light generated from the light source part.5. The coherence-adjustable digital holography system according to claim 1 , wherein the dispersion part comprises a triangular or annular prism.6. The coherence-adjustable digital holography system according to claim 1 , wherein the adjustment part comprises at least one slit or iris for adjusting a selection frequency of the light.7. The coherence-adjustable digital holography system ...

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04-01-2018 дата публикации

SYSTEM, APPARATUS AND METHOD FOR EXTRACTING THREE-DIMENSIONAL INFORMATION OF AN OBJECT FROM RECEIVED ELECTROMAGNETIC RADIATION

Номер: US20180004158A1
Автор: BROOKER Gary, ROSEN Joseph
Принадлежит: CELLOPTIC, INC.

An apparatus and method to produce a hologram of an object includes an electromagnetic radiation assembly configured to receive a received electromagnetic radiation, such as light, from the object. The electromagnetic radiation assembly is further configured to diffract the received electromagnetic radiation and transmit a diffracted electromagnetic radiation. An image capture assembly is configured to capture an image of the diffracted electromagnetic radiation and produce the hologram of the object from the captured image. 1. An apparatus configured to produce a hologram of an object , said apparatus comprising:an electromagnetic source configured to provide incoherent electromagnetic radiation on the object;a correlator comprising a first optical assembly configured to receive incoherent electromagnetic radiation reflected by or scattered from the object and transmit transformed electromagnetic radiation, a mask assembly configured to receive the transformed electromagnetic radiation and transmit amplitude and/or phase modified electromagnetic radiation, and a second optical assembly configured to receive the amplitude and/or phase modified electromagnetic radiation and further transmit transformed electromagnetic radiation;an image capture assembly configured to capture an image of the further transmitted transformed electromagnetic radiation; anda processing system including at least one processor, the processing system configured to produce the hologram of the object based on the captured image.2. The apparatus of claim 1 , wherein the first optical assembly claim 1 , the mask assembly claim 1 , the second optical assembly claim 1 , and the image capture assembly are disposed along a common optical path.3. The apparatus of claim 1 , wherein the mask assembly includes one or more diffractive optical elements claim 1 , each of the one or more diffractive optical elements including an array of plural transform regions claim 1 , each of which is configured to ...

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12-01-2017 дата публикации

Real-Time 3D Virtual or Physical Model Generating Apparatus for HoloPortal and HoloCloud System

Номер: US20170010584A1
Автор: KIM Heekwan
Принадлежит:

A novel electronic system provides fast three-dimensional model generation, social content sharing of dynamic three-dimensional models, and monetization of the dynamic three-dimensional models created by casual consumers. In one embodiment, a casual consumer utilizes a dedicated real-time D model reconstruction studio with multiple camera angles, and then rapidly create dynamic D models with novel computational methods performed in scalable graphics processing units. In another embodiment, uncalibrated multiple sources of video recording of a targeted object are provided by a plurality of commonly-available consumer video recording devices (e.g. a smart phone, a camcorder, a digital camera, etc.) located at different angles, after which the uncalibrated multiple sources of video recording are transmitted to a novel cloud computing system for real-time temporal, spatial, and photometrical calibration and D model reconstruction. The dynamic D models can be uploaded, listed, and shared among content creators and viewers in an electronic sharing platform. 1. A real-time 3D virtual and physical body double-generating apparatus comprising:a HoloPortal electronic system that incorporates a dedicated physical studio space, which is configured to capture, calibrate, calculate, reconstruct, and generate graphical transformation of a target object to create an electronic 3D body double model;a HoloCloud electronic system comprising consumer-level portable video recording devices positioned circularly around the target object and generate a plurality of multiple-angle video data streams, a scalable number of graphics processing units (GPU's) that execute a pre-processing module and a 3D reconstruction module for calibrating, calculating, reconstructing, and generating graphical transformations to create the electronic 3D body double model that resembles the target object, and a wireless transceiver that transmits the plurality of multiple-angle video data streams from the ...

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14-01-2016 дата публикации

Method for regulating the relative position of an analyte in relation to a light beam

Номер: US20160011117A1

A method for regulating the relative position of an analyte of a sample ( 16 ) in relation to a light beam (F) includes the illumination of the analyte of the sample ( 16 ) with the light beam (F), capturing by an imaging device ( 38 ) a transmission image of the beams scattered by the analyte of the sample ( 16 ) in order to establish a diffraction pattern, and modifying the relative position of the analyte of the sample ( 16 ) in relation to the light beam (F) according to at least one property of the diffraction pattern.

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11-01-2018 дата публикации

Large Area Lens-Free Imaging Device

Номер: US20180011443A1
Принадлежит: IMEC VZW

Embodiments described herein relate to a large area lens-free imaging device. One example is a lens-free device for imaging one or more objects. The lens-free device includes a light source positioned for illuminating at least one object. The lens-free device also includes a detector positioned for recording interference patterns of the illuminated at least one object. The light source includes a plurality of light emitters that are positioned and configured to create a controlled light wavefront for performing lens-free imaging. 1. A lens-free device for imaging one or more objects , the lens-free device comprising:a light source positioned for illuminating at least one object; anda detector positioned for recording interference patterns of the illuminated at least one object,wherein the light source comprises a plurality of light emitters that are positioned and configured to create a controlled light wavefront for performing lens-free imaging.2. The lens-free device according to claim 1 , wherein the plurality of light emitters comprises a photonic phased array.3. The lens-free device according to claim 1 , wherein the controlled light wavefront comprises a quasi-planar wavefront for performing large-area claim 1 , lens-free imaging.4. The lens-free device according to claim 1 , wherein the light emitters comprise grating couplers.5. The lens-free device according to claim 1 , wherein the light emitters comprise micro-structures fabricated in a slab of material suitable for propagating light.6. The lens-free device according to claim 1 , wherein the light source further comprises an optical distribution network configured for distributing a light signal to the plurality of light emitters.7. The lens-free device according to claim 6 , wherein the optical distribution network is designed such that a phase difference between adjacent light emitters is an integer multiple of 2π.8. The lens-free device according to claim 1 , wherein the lens-free device is a silicon ...

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14-01-2021 дата публикации

Quantum simulator and quantum simulation method

Номер: US20210011430A1

A quantum simulator includes a pseudo speckle pattern generator, a main vacuum chamber, an atomic gas supply unit, a light beam generator, a photodetector, and an atom number detector. The pseudo speckle pattern generator generates a pseudo speckle pattern in the inside of the main vacuum chamber by light allowed to enter the inside of the main vacuum chamber through the second window. The pseudo speckle pattern generator includes a controller, a light source, a beam expander, a spatial light modulator, and a lens. The controller sets a modulation distribution of the spatial light modulator based on a two-dimensional pseudo random number pattern.

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10-01-2019 дата публикации

LENS-FREE HOLOGRAPHIC OPTICAL SYSTEM FOR HIGH SENSITIVITY LABEL-FREE MICROBIAL GROWTH DETECTION AND QUANTIFICATION FOR SCREENING, IDENTIFICATION, AND SUSCEPTIBILITY TESTING

Номер: US20190011882A1
Автор: Gusyatin Oleg
Принадлежит: Accelerate Diagnostics, Inc.

Disclosed are optical interrogation apparatus that can produce lens-free images using an optoelectronic sensor array to generate a holographic image of sample objects, such as microorganisms in a sample. Also disclosed are methods of detecting and/or identifying microorganisms in a biological sample, such as microorganisms present in low levels. Also disclosed are methods of using systems to detect microorganisms in a biological sample, such as microorganisms present in low levels. In addition or as an alternative, the methods of using systems may identify microorganisms present in a sample and/or determine antimicrobial susceptibility of such microorganisms. 1. An automated system , comprising:an automated holographic optical apparatus situated to determine at least antimicrobial susceptibility of a microorganism corresponding to an object in a sample volume based on a detected variation over time of a hologram of the sample volume, an output of at least one deeply supervised convolutional neural network, and a phenotypical behavior of the microorganism, wherein the phenotypical behavior of the microorganism is classified based on the detected variation and the output of the at least one deeply supervised convolutional neural network.2. The system of claim 1 , wherein the holographic apparatus is an in-line holographic apparatus and the hologram is an in-line hologram;wherein the in-line holographic optical apparatus includes a reference beam source situated to direct a reference beam to the sample volume, a sample receptacle situated to hold the sample volume in view of the reference beam, an optical sensor situated to detect the in-line hologram formed by the reference beam and the sample volume, and a controller coupled to the optical sensor and that includes at least one processor and one or more computer-readable storage media including stored instructions that, responsive to execution by the at least one processor, cause the controller to determine the ...

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12-01-2017 дата публикации

HoloPortal and HoloCloud System and Method of Operation

Номер: US20170013246A1
Автор: Heekwan Kim
Принадлежит: Doubleme Inc

A novel electronic system provides fast three-dimensional model generation, social content sharing of dynamic three-dimensional models, and monetization of the dynamic three-dimensional models created by casual consumers. In one embodiment, a casual consumer utilizes a dedicated real-time 3D model reconstruction studio with multiple camera angles, and then rapidly create dynamic 3D models with novel computational methods performed in scalable graphics processing units. In another embodiment, uncalibrated multiple sources of video recording of a targeted object are provided by a plurality of commonly-available consumer video recording devices (e.g. a smart phone, a camcorder, a digital camera, etc.) located at different angles, after which the uncalibrated multiple sources of video recording are transmitted to a novel cloud computing system for real-time temporal, spatial, and photometrical calibration and 3D model reconstruction. The dynamic 3D models can be uploaded, listed, and shared among content creators and viewers in an electronic sharing platform.

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12-01-2017 дата публикации

3D Virtual Reality Model Sharing and Monetization Electronic Platform System

Номер: US20170013247A1
Автор: Heekwan Kim
Принадлежит: Doubleme Inc

A novel electronic system provides fast three-dimensional model generation, social content sharing of dynamic three-dimensional models, and monetization of the dynamic three-dimensional models created by casual consumers. In one embodiment, a casual consumer utilizes a dedicated real-time 3D model reconstruction studio with multiple camera angles, and then rapidly create dynamic 3D models with novel computational methods performed in scalable graphics processing units. In another embodiment, uncalibrated multiple sources of video recording of a targeted object are provided by a plurality of commonly-available consumer video recording devices (e.g. a smart phone, a camcorder, a digital camera, etc.) located at different angles, after which the uncalibrated multiple sources of video recording are transmitted to a novel cloud computing system for real-time temporal, spatial, and photometrical calibration and 3D model reconstruction. The dynamic 3D models can be uploaded, listed, and shared among content creators and viewers in an electronic sharing platform.

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19-01-2017 дата публикации

DEVICES AND METHODS FOR HOLOGRAPHIC 3D IMAGING

Номер: US20170017202A1
Автор: LIU Yunhui, LU Yujie
Принадлежит:

A device, system and method for holographic 3D imaging. The device includes a laser light source that delivers a laser beam; an aperture disc including at least two pinholes, the laser beam being filtered by the pinholes so that a reference wave and an object wave are generated; a sample having a first area containing an object to be imaged and a second area without any object, in which the first area and the second area are illuminated by the object wave and the reference wave respectively; and an image sensor that captures an off-axis hologram for reconstructing an image of the object, in which the reference wave and the object wave are interfered on the image sensor and the hologram is captured based on an interference pattern of the reference wave and the object wave. 1. A device , comprising:a laser light source that delivers a laser beam;an aperture disc comprising at least two pinholes, the laser beam being filtered by the pinholes so that a reference wave and an object wave are generated;a sample having a first area containing an object to be imaged and a second area without any object, wherein the first area and the second area are illuminated by the object wave and the reference wave respectively; andan image sensor that captures an off-axis hologram for reconstructing an image of the object, wherein the reference wave and the object wave are interfered on the image sensor and the hologram is captured based on an interference pattern of the reference wave and the object wave.2. The device of claim 1 , wherein a distance between the sample and the aperture disc is smaller than a distance between the sample and the image sensor.3. The device of claim 1 , wherein the laser beam is collimated or roughly collimated claim 1 , illuminates the image sensor perpendicularly claim 1 , and is focused or roughly focused at a center of the image sensor.4. The device of claim 1 , wherein the laser beam is in visible spectrum claim 1 , infrared spectrum or ultraviolet ...

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18-01-2018 дата публикации

METHOD AND APPARATUS FOR PROCESSING THREE-DIMENSIONAL IMAGE

Номер: US20180017938A1
Принадлежит: SAMSUNG ELECTRONICS CO., LTD.

A method and apparatus for processing a three-dimensional image are provided. The method includes receiving original color data and original depth data of a plurality of layers of an original holographic image, selecting reference layers from among the plurality of layers, mapping adjustment color data of a non-selected layer, which is determined based on using the original depth data of the non-selected layer and the reference layers, to each of the reference layers, and generating a computer generated hologram image by using the original color data of the reference layers and the adjustment color data that has been mapped to the reference layers. 1. A method for processing a three-dimensional image , the method comprising:receiving original color data and original depth data of each of a plurality of layers with respect to an original holographic image;selecting at least one reference layer from among the plurality of layers;mapping adjustment color data of a non-selected layer, which is determined based on the original depth data of the non-selected layer and the at least one reference layer, to each of the at least one reference layer; andgenerating a computer generated hologram (CGH) image based on the original color data of the at least one reference layer and the mapped adjustment color data.2. The method of claim 1 , wherein the mapping the adjustment color data comprises:determining respective adjustment color values of pixels included in the non-selected layer in correspondence with each of the at least one reference layer based on a respective distance between the non-selected layer and each of the at least one reference layer; andmapping the determined adjustment color values of the pixels to each of the at least one reference layer.3. The method of claim 2 , wherein the determining the adjustment color values comprises determining the respective adjustment color values by applying a respective weight value that corresponds to each respective distance to ...

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18-01-2018 дата публикации

DEVICE FOR OBSERVING A SAMPLE

Номер: US20180017939A1

The invention relates to a device for observing a sample, including: 2. The Device according to claim 1 , wherein the emission surface of the micron-sized light-emitting diode has a diameter or a largest diagonal smaller than 150 μm or than 50 μm or than 10 μm.3. The Device according to claim 1 , wherein the light source includes a plurality of micron-sized light-emitting diodes.4. The Device according to claim 3 , wherein the micron-sized light-emitting diodes are arranged in a matrix array claim 3 , the diodes being spaced apart from one another by a distance smaller than 50 μm.5. The Device according to claim 3 , wherein the micron-sized light-emitting diodes have emission spectral bands that are different from one another and are able to be activated successively or simultaneously.6. The Device according to claim 3 , wherein the micron-sized light-emitting diodes are configured to be activated independently of one another.8. The Method according to claim 7 , wherein the largest diameter or largest diagonal of the micron-sized light-emitting diode is smaller than 150 μm or than 50 μm.9. The Method according to claim 7 , wherein the light source includes a plurality of micron-sized light-emitting diodes.10. The Method according to claim 9 , wherein the micron-sized light-emitting diodes are activated successively claim 9 , the image sensor acquiring one image during each successive activation.11. The Method according to claim 9 , wherein the micron-sized light-emitting diodes have spectral emission bands that are different from one another.12. The Method according to claim 9 , wherein claim 9 , the image sensor lies in a detection plane and wherein the method includes applying a propagation operator to each acquired image claim 9 , so as to obtain a complex expression of a light wave to which the image sensor is exposed claim 9 , in a reconstruction plane claim 9 , the reconstruction plane being located at a nonzero distance from the detection plane.13. The Method ...

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25-01-2018 дата публикации

APPARATUS FOR CHARACTERIZING BIOLOGICAL OBJECTS

Номер: US20180023111A1
Принадлежит:

In order to quantitatively characterize biological objects, for example individual cells, a stimulus is applied to a biological object () in a contactless fashion. A measurement and a further measurement are performed on the biological object () in order to ascertain a response of the biological object () to the stimulus, wherein the measurement and the further measurement comprise detecting Raman scattering on and/or in the biological object () and/or capturing data using digital holographic microinterferometry (DHMI). The biological object () is characterized according to a result of the measurement and is sorted if needed. The stimulus can be applied by means of a laser beam that creates optical tweezers or an optical trap, by means of ultrasonic waves or an electric or magnetic radio frequency field. 1. An apparatus for characterizing a biological object , comprisinga device for holding a biological object in a position where a stimulus can be applied to the biological object; wherein the measurement device is configured for data acquisition by a detection of Raman scattering on the biological object;', 'wherein the measurement device is further configured for ascertaining the response of the biological object to the stimulus, said measurement device performing a measurement comprising a detection of the Raman scattering before application of the stimulus, and performing a further measurement comprising a further detection of the Raman scattering after or during application of the stimulus; and, 'a measurement device for performing a measurement on the biological object to ascertain a response of the biological object to the stimulus;'}an evaluation logic configured to compare results of the measurement performed before application of the stimulus and results of the further measurement performed after or during application of the stimulus, and to characterize the biological object as a function of a comparison of the results of the measurement and of the further ...

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26-01-2017 дата публикации

APPARATUS AND METHOD FOR QUANTITIVE PHASE TOMOGRAPHY THROUGH LINEAR SCANNING WITH COHERENT AND NON-COHERENT DETECTION

Номер: US20170023472A1
Принадлежит:

The disclosed invention describes a new apparatus performing a new data acquisition for quantitative refractive index tomography. It is based on a linear scanning of the specimen, opposed to the classical approaches based on rotations of either the sample or the illumination beam, which are based on the illumination with plane waves, which orientation is successively modified in order to acquire angular information. On the contrary, the inventive apparatus and method rely on a specially shaped illumination, which provides straightforwardly an angular distribution in the illumination of the specimen. The specimen can thus be linearly scanned in the object plane in order to acquire the data set enabling tomographic reconstruction, where the different positions directly possess the information on various angles for the incoming wave vectors. 117.-. (canceled)18. An apparatus for performing quantitative phase tomography on a specimen , comprising:an illumination source for providing an illuminating beam;an optical device having an optical axis direction, the optical device arranged to transform the illuminating beam into a shaped illuminating beam directed along the optical axis direction to irradiate the specimen;a microscope objective arranged to collect a beam scattered by the specimen; and an array sensor for measuring an intensity of the beam scattered by the specimen and collected by the microscope objective, and outputting a measurement signal,', 'displacement device to move the specimen in a plane normal to the optical axis direction, and', 'a processing device to process the measurement signal output by the array sensor to deliver quantitative phase tomography images representing the specimen in three dimensions, and to provide quantitative values of a refractive index distribution., 'a wave front analyzer for analyzing a wave field amplitude and phase of the beam scattered by the specimen, the wave front analyzer including,'}19. The apparatus of claim 18 , ...

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26-01-2017 дата публикации

Themed Holographic Theater

Номер: US20170023911A1
Принадлежит: Individual

A themed holograph theater system and method for presenting interactive holographic imagery that presents 2D or 3D holographic imagery interactive with physical objects. The themed holographic theater system includes a camera or scanner to obtain data concerning the physical object, a projector to project images on a holographic media and a program to identify the physical object based on the camera or scanner data and control the projection of images interacting with the physical object.

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10-02-2022 дата публикации

ON-AXIS AND OFF-AXIS DIGITAL HOLOGRAM GENERATING DEVICE AND METHOD

Номер: US20220043393A1
Принадлежит: NAEILHAE, CO. LTD.

Provided are on-axis and off-axis digital hologram generating device and method. 1. An on-axis and off-axis digital hologram generating device , the device comprising:a controller; andan input window configured to receive user input of hologram property information, access a phase file of an object stored in a storage device;', 'convert the phase file of the object into object phase information in a useable form;', 'generate digital object light information based on a light property of object light input by a user and the converted object phase information; and', 'generate a digital hologram based on (i) the received hologram property information, (ii) the generated digital object light information, and (iii) digital reference light information inputted by a user., 'wherein the controller is configured to'}2. The device of claim 1 , wherein physical information of the object light comprises light wavelength information claim 1 , wavenumber information claim 1 , and amplitude information of the object light claim 1 , and the digital object light information comprises an object recorded position claim 1 , object phase information claim 1 , and light property information.3. The device of claim 1 , wherein the on-axis and off-axis digital hologram generating device further comprises:a digital object light information input unit configured to receive input of the digital object light information.4. The device of claim 1 , wherein the hologram property information is a property parameter of an image sensor to which the digital hologram is generated and recorded claim 1 , and an interference mode parameter.5. The device of claim 4 , wherein the property parameter of the image sensor comprises a resolution claim 4 , a bit depth claim 4 , and a pixel size claim 4 , and the interference mode parameter is one among an on-axis interference mode claim 4 , an off-axis interference mode claim 4 , and a space movement off-axis interference mode.6. An on-axis and off-axis digital ...

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24-01-2019 дата публикации

SYSTEMS AND METHODS FOR FABRICATING VARIABLE DIGITAL OPTICAL IMAGES BY PRINTING DIRECTLY ON GENERIC OPTICAL MATRICES

Номер: US20190025758A1
Автор: LIEBERMAN DANIEL
Принадлежит: NANOGRAFIX CORPORATION

Variable digital optical images may be fabricated using generic optical matrices. A generic optical matrix may have a substrate and a plurality of pixels corresponding to color and sub-pixels corresponding to non-color effects. The pixels may include first pixels corresponding to a first color and second pixels corresponding to a second color. The sub-pixels may include first sub-pixels corresponding to a first non-color effect and second sub-pixels corresponding to a second non-color effect. Individual ones of the pixels and sub-pixels of the generic optical matrix may be obliterated according to a negative while remaining pixels and/or sub-pixels may be preserved. The remaining pixels and sub-pixels may form an optical image corresponding to a base image. The optical image may be colored based on the remaining pixels. The optical image may exhibit non-color effects corresponding to the remaining sub-pixels. The optical image may comprise a hologram or a stereo image. 1. A system configured for fabricating variable digital optical images using generic optical matrices , the system comprising:an image negative component configured to retain a negative corresponding to a base image, the negative being based on the base image and a geometry associated with a generic optical matrix having a substrate and an array of pixels disposed on the substrate,the array of pixels comprising a plurality pixels corresponding to a plurality of colors, the plurality of pixels corresponding to a plurality of colors being arranged such that individual ones of the pixels of a first color are positioned adjacent to individual ones of the pixels of a second color;wherein individual ones of the pixels comprise sub-pixels, the subpixels comprising a first sub-pixel corresponding to a first non-color effect and a second sub-pixel corresponding to a second non-color effect; andan image generation component configured to obliterate individual pixels and sub-pixels of the generic optical matrix ...

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02-02-2017 дата публикации

Apparatus and Method for Performing In-Line Lens-Free Digital Holography of an Object

Номер: US20170031318A1
Принадлежит: IMEC VZW

The present disclosure relates to apparatuses and methods for performing in-line lens-free digital holography of objects. At least one embodiment relates to an apparatus for performing in-line lens-free digital holography of an object. The apparatus includes a point light source adapted for emitting coherent light. The apparatus also includes an image sensing device adapted and arranged for recording interference patterns resulting from interference from light waves directly originating from the point light source and object light waves. The object light waves originate from light waves from the point light source that are scattered or reflected by the object. The image sensing device comprises a plurality of pixels. The point light source comprises a broad wavelength spectrum light source and a pinhole structure. The image sensing device comprises a respective narrow band wavelength filter positioned above each pixel that filters within a broad wavelength spectrum of the point light source. 1. An apparatus for performing in-line lens-free digital holography of an object , comprising:a point light source adapted for emitting coherent light; andan image sensing device adapted and arranged for recording interference patterns resulting from interference from light waves directly originating from the point light source and object light waves,wherein the object light waves originate from light waves from the point light source that are scattered or reflected by the object, wherein the point light source comprises a broad wavelength spectrum light source and a pinhole structure, the broad wavelength spectrum light source being arranged to emit light towards the pinhole structure,', 'wherein the image sensing device comprises, for each of the disjoint subsets of pixels, a respective narrow band wavelength filter positioned above each pixel in the disjoint subset of pixels,, 'wherein the image sensing device comprises a plurality of pixels apportioned between disjoint ...

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31-01-2019 дата публикации

DIGITAL 2D HOLOGRAPHIC SPECTROMETER FOR MATERIAL CHARACTERIZATION

Номер: US20190032484A1
Принадлежит:

A tool including a probe deployable within a wellbore and an optical analysis device coupled to the probe is provided. The optical analysis device includes a two-dimensional (2D) waveguide layer to transmit and to disperse an electromagnetic radiation according to wavelength and including detector elements disposed along an edge, each detector element providing a signal associated with a pre-determined wavelength portion of the electromagnetic radiation. The optical analysis device also includes a substrate layer electrically coupled to receive the signal from each of the detector elements and form a spectrum of the electromagnetic radiation with the processor. A method for using the tool in a wellbore application, a pipeline application, or a reservoir storage application is also provided. 1. A tool , comprising:a probe deployable within a wellbore; and a two-dimensional (2D) waveguide layer to transmit and to disperse electromagnetic radiation according to wavelength, the 2D waveguide layer including a plurality of detector elements disposed along an edge of the 2D waveguide layer so that each detector element provides a signal associated with a pre-determined wavelength portion of the electromagnetic radiation; and', 'a substrate layer including a processor, the substrate layer being electrically coupled to the 2D waveguide layer to receive the signal from each detector element and form a spectrum of the electromagnetic radiation with the processor., 'an optical analysis device coupled to the probe, the optical analysis device including2. The tool of claim 1 , wherein the optical analysis device is removably coupled to the probe.3. The tool of claim 1 , further including a microfluidic device coupled with the optical analysis device to provide a fluid sample to interact with the electromagnetic radiation prior to transmitting the electromagnetic radiation to the 2D waveguide layer.4. The tool of claim 1 , further including a light source optically coupled with ...

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01-02-2018 дата публикации

IMAGING SYSTEMS AND METHODS OF USING THE SAME

Номер: US20180033128A1
Принадлежит:

Method and system for lensless, shadow optical imaging. Formation of a hologram shadow image having higher spatial resolution and lower noise level is accomplished by processing image information contained in multiple individual hologram shadow image frames acquired either under conditions of relative shift between point light source and the detector of the system or under stationary conditions, when system remains fixed in space and is devoid of any relative movement during the process of acquisition of individual image frames. 1. A shadow optical imaging method comprising:receiving, at a single detector of a lensless optical imaging system, an optical shadow cast thereon by an object disposed in immediate proximity to said single detector and irradiated with a single diverging monochromatic wavefront of light; wherein spatial positions and orientations of said detector, said object, and said light source remain unchanged during said acquiring;', 'wherein said wavefront has a rate of spatial divergence that remains unchanged in time and an optical axis the spatial orientation of which remains unchanged during said period of time,', 'wherein said first image is characterized by first spatial resolution;, 'acquiring multiple sets of optical data with said single detector over a period of time, each set of optical data representing a respectively-corresponding first image of said optical shadow formed with said wavefront at a respectively-corresponding point in time within said period,'} 'wherein said second image is characterized by second spatial resolution, the second spatial resolution being higher than the first spatial resolution.', 'from said multiple sets of optical data, forming a second image of said object with a computer processor, said forming including anisotropic filtering of a set from said multiple sets to correct geometrical information of each first image,'}2. A method according to claim 1 , wherein said receiving includes receiving said optical ...

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04-02-2021 дата публикации

METHOD FOR PHOTOCOPYING A SEQUENCE OF CUT SURFACES INSIDE A LIGHT-SCATTERING OBJECT WITH IMPROVED SCANNING

Номер: US20210034863A1
Принадлежит:

The invention relates to a free-beam interferometric method for illuminating a sequence of sectional areas in the interior of the light-scattering object. The method makes it possible for the user to select a larger image field and/or a higher image resolution than previously possible with the occurrence of self-interference of the specimen light from a scattering specimen. 2. The method according to claim 1 , wherein the phase gradient along the predetermined axis in the camera plane is established on half the Nyquist frequency.3. The method according to any one of the preceding claims claim 1 , wherein a surrounding interval of the indexing is predetermined for each indexed camera image of at least a partial number of the detected camera images and a weighted stack mean value of all the camera images of the surrounding interval is calculated and the calculated stack mean value of the indexed camera image is deducted to calculate the structurally improved camera image.4. The method according to claim 3 , further comprising calculation of the images of the sectional areas in the interior of the object by two-dimensional Fourier filtering of the structurally improved camera images.5. The method according to claim 1 , wherein the light-scattering object is the retina of a living eye.6. The method according to claim 5 , further comprising biometric verification of the identity of a user. The invention relates to a method for illuminating sectional areas in the interior of a light-scattering object, wherein light of a short-coherent light source is split into a specimen light beam and a reference light beam and fed to a specimen arm and a reference arm variable in its length and thereafter superimposed on a two-dimensional light detector.Interferometric methods of the generic type are known, amongst other things, for optical coherence tomography (OCT). In particular, it is possible by means of free-beam interferometers to detect simultaneously the whole of the light ...

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11-02-2016 дата публикации

SYSTEM AND METHOD FOR APPLYING ORTHOGONAL LIMITATIONS TO LIGHT BEAMS USING MICROELECTROMECHANICAL SYSTEMS

Номер: US20160041523A1
Принадлежит:

A system for generating a light beam having a plurality of orthogonal function modes includes a light source for generating a plane wave light beam. A MicroElectroMechanical (MEM) system including an array of micro-mirrors for generating the light beam having the plurality of orthogonal function modes applied thereto responsive to the plane wave light beam and control signals for controlling the array of micro-mirrors. A controller generates the control signals to control a position of each of a plurality of micro-mirrors of the array of micro-mirrors. The controller controls the position of the micro-mirrors to generate a plurality of holograms for applying the plurality of orbital angular momentum modes to the plane wave light beam responsive to the control signals. 1. A system for generating a light beam having a plurality of orbital angular momentum modes applied thereto , comprising:a light source for generating a plane wave light beam;a MicroElectroMechanical (MEM) system including an array of micro-mirrors for generating the light beam having the plurality of orbital angular momentum modes applied thereto responsive to the plane wave light beam and control signals for controlling the array of micro-mirrors;a controller for generating the control signals to control a position of each of a plurality of micro-mirrors of the array of micro-mirrors; andwherein the controller controls the position of the micro-mirrors to generate a plurality of holograms for applying the plurality of orbital angular momentum modes to the plane wave light beam responsive to the control signals.2. The system of claim 1 , wherein the controller switches the array of micro-mirrors between different holograms to dynamically control helicities applied to the light beam from the MEM system.3. The system of claim 1 , wherein the controller controls the array of micro-mirrors to produce holograms having a radius substantially in a range of 100-200 micro-mirrors and a period substantially in ...

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09-02-2017 дата публикации

MOBILE DEVICE WIRELESS CHARGING SYSTEM

Номер: US20170040835A1
Принадлежит:

A wireless charging system for charging a mobile device uses a supercapacitor to provide wireless charging of the device. A holographic image of the supercapacitor may store electrical charge which may be released for storage into the battery of the device. 1. A wireless charging system for supplying a stored charge to a mobile device , comprising:a receiver in a mobile device configured to receive a wireless signal of an image of an electrically charged, holographic supercapacitor;a storage medium in the mobile device for storing the image of the electrically charged, holographic supercapacitor; anda trigger mechanism in the mobile device configured to release electric charge from the image of the electrically charged, holographic supercapacitor for storage into a battery of the mobile device.2. The wireless charging system of claim 1 , wherein the trigger mechanism includes a computer program product with computer readable code configured to translate data in the image of the electrically charged claim 1 , holographic supercapacitor into an electric charge.3. The wireless charging system of claim 1 , wherein the image of the electrically charged claim 1 , holographic supercapacitor is of a graphene based object.4. The wireless charging system of claim 3 , wherein the graphene based object is pyramidal shaped graphene structure.5. The wireless charging system of claim 4 , wherein the pyramidal shaped graphene structure is coupled to an aerogel based circuit substrate.6. A computer program product for wirelessly charging a mobile device claim 4 , the computer program product comprising a non-transitory computer readable storage medium having computer readable program code embodied therewith claim 4 , the computer readable program code being configured to:capture an image of an electrically charged, holographic supercapacitor;transfer the image of an electrically charged, holographic supercapacitor wirelessly to a mobile device;translate data in the image of the ...

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07-02-2019 дата публикации

LENS-FREE IMAGE SENSOR USING PHASE-SHIFTING HOLOGRAM

Номер: US20190041794A1
Принадлежит:

An image sensor is provided. The image sensor includes: a plurality of photoelectric elements for receiving an incident light. The photoelectric elements are arranged into a plurality of unit cells, and each of the unit cells includes a first photoelectric element and a second photoelectric element. The first photoelectric element in each of the unit cells captures a first pixel in a first phase, and the second photoelectric element in each of the unit cells captures a second pixel in a second phase, wherein the first phase is different from the second phase. 1. An image sensor , comprising:a plurality of photoelectric elements for receiving an incident light,wherein the photoelectric elements are arranged into a plurality of unit cells, and each of the unit cells comprises a first photoelectric element and a second photoelectric element,wherein the first photoelectric element in each of the unit cells captures a first pixel in a first phase, and the second photoelectric element in each of the unit cells captures a second pixel in a second phase,wherein the first phase is different from the second phase.2. The image sensor as claimed in claim 1 , wherein each of the unit cells further comprises a third photoelectric element capturing a third pixel in a third phase and a fourth photoelectric element capturing a fourth pixel in a fourth phase claim 1 ,wherein the first phase, the second phase, the third phase, and the fourth phase are different.3. The image sensor as claimed in claim 2 , wherein the first photoelectric element claim 2 , the second photoelectric element claim 2 , the third photoelectric element claim 2 , and the fourth photoelectric element in each of the unit cells are made of a specific material claim 2 , and are different heights.4. The image sensor as claimed in claim 3 , wherein the first phase claim 3 , the second phase claim 3 , the third phase claim 3 , and the fourth phase are 0 claim 3 , π/2 claim 3 , π claim 3 , and 3π/2 claim 3 , ...

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18-02-2021 дата публикации

SYSTEMS AND METHODS FOR FABRICATING VARIABLE DIGITAL OPTICAL IMAGES USING GENERIC OPTICAL MATRICES

Номер: US20210048779A1
Принадлежит: NANOGRAFIX CORPORATION

Variable digital optical images may be fabricated using generic optical matrices. A generic optical matrix may have pixels corresponding to color and subpixels corresponding to noncolor effects. The pixels may include first pixels corresponding to a first color and second pixels corresponding to a second color. The subpixels may include first subpixels corresponding to a first noncolor effect and second subpixels corresponding to a second noncolor effect. Individual ones of the pixels and/or subpixels of the generic optical matrix may be obliterated according to a negative while remaining pixels and/or subpixels may be preserved. The remaining pixels and/or subpixels may form an optical image corresponding to a base image. The optical image may be colored based on the remaining pixels. The optical image may exhibit noncolor effects corresponding to the remaining subpixels. The optical image may comprise a hologram or a stereo image. 1. A generic optical matrix having pixels corresponding to color and sub-pixels corresponding to non-color effects , the generic optical matrix comprising: a substrate; andan array of pixels disposed on the substrate, the array comprising first pixels corresponding to a first color and second pixels corresponding to a second color, the first color being different from the second color, the first pixels and second pixels being arranged in a motif such that individual ones of the first pixels are positioned adjacent to individual ones of the second pixels; wherein individual ones of the pixels comprise sub-pixels, a given pixel comprising a first sub-pixel and a second sub-pixel, the first sub-pixel comprising a first optical structure configured such that light reflected or transmitted by the first optical structure of the first sub-pixel is directed toward a left eye of a person observing the generic optical matrix from a first viewing angle, the second sub-pixel comprising a second optical structure configured such that light reflected ...

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16-02-2017 дата публикации

METHOD AND SYSTEM FOR DETECTING AT LEAST ONE PARTICLE IN A BODILY FLUID, AND ASSOCIATED METHOD FOR DIAGNOSING MENINGITIS

Номер: US20170045439A1
Принадлежит:

This method for detecting at least one particle in a bodily fluid is carried out via a detection system including a light source, a transparent substrate and a photodetector array, the substrate being positioned between the light source and the photodetector. This method includes the placement of a droplet of bodily fluid on the substrate, the illumination of the droplet via the light source, the acquisition of several successive images of the droplet via the photodetector, each image being formed by radiation transmitted by the illuminated droplet and including at least one elementary diffraction pattern, each elementary diffraction pattern corresponding to waves diffracted by a particle upon illumination of the droplet, the identification, via the acquired images of the mobile elementary diffraction patterns, and the counting of moving particles in the droplet, via the identified mobile elementary diffraction patterns. 112-. (canceled)13. A method for detecting at least one particle in a bodily fluid , with a detection system comprising a light source , a transparent substrate and a photodetector array , the transparent substrate being positioned between the light source and the photodetector array , placing the bodily fluid as a droplet on the transparent substrate,', 'illuminating the droplet with the light source,', 'acquiring several successive images of the droplet with the photodetector array, each image being formed by radiation transmitted through the illuminated droplet and including at least one elementary diffraction pattern, each elementary diffraction pattern corresponding to waves diffracted by a particle during the illumination of the droplet,', 'identifying, from the acquired images, mobile elementary diffraction patterns,', 'counting moving particles within the droplet, from the thereby identified mobile elementary diffraction patterns., 'the method comprising14. The method according to claim 13 , wherein the method further comprises heating the ...

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15-02-2018 дата публикации

Lens-Free Imaging

Номер: US20180046139A1
Принадлежит: IMEC VZW

Embodiments described herein relate to lens-free imaging. One example embodiment may include a lens-free imaging device for imaging a moving sample. The lens-free imaging device may include a radiation source configured to emit a set of at least two different wavelengths towards the moving sample. The lens-free imaging device is configured to image samples for which a spectral response does not substantially vary for a set of at least two different wavelengths. The lens-free imaging device may also include a line scanner configured to obtain a line scan per wavelength emitted by the radiation source and reflected by, scattered by, or transmitted through the moving sample. The line scanner is configured to regularly obtain a line scan per wavelength. Either the radiation source or the line scanner is configured to isolate data of the at least two different wavelengths. 1. A lens-free imaging device for imaging a moving sample , comprising:a radiation source configured to emit a set of at least two different wavelengths towards the moving sample, wherein the lens-free imaging device is configured to image samples for which a spectral response does not substantially vary for a set of at least two different wavelengths; anda line scanner configured to obtain a line scan per wavelength emitted by the radiation source and reflected by, scattered by, or transmitted through the moving sample,wherein the line scanner is configured to regularly obtain a line scan per wavelength, andwherein either the radiation source or the line scanner is configured to isolate data of the at least two different wavelengths.2. The lens-free imaging device according to claim 1 , further comprising:a processor programmed to stitch the obtained line scans per wavelength to obtain, for each wavelength, an image of the sample.3. The lens-free imaging device according to claim 2 , wherein the processor is further programmed to recombine a plurality of images of the sample to obtain a combined image ...

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03-03-2022 дата публикации

LENS-FREE HOLOGRAPHIC OPTICAL SYSTEM FOR HIGH SENSITIVITY LABEL-FREE MICROBIAL GROWTH DETECTION AND QUANTIFICATION FOR SCREENING, IDENTIFICATION, AND SUSCEPTIBILITY TESTING

Номер: US20220066390A1
Автор: Gusyatin Oleg
Принадлежит: Accelerate Diagnostics, Inc.

Disclosed are optical interrogation apparatus that can produce lens-free images using an optoelectronic sensor array to generate a holographic image of sample objects, such as microorganisms in a sample. Also disclosed are methods of detecting and/or identifying microorganisms in a biological sample, such as microorganisms present in low levels. Also disclosed are methods of using systems to detect microorganisms in a biological sample, such as microorganisms present in low levels. In addition or as an alternative, the methods of using systems may identify microorganisms present in a sample and/or determine antimicrobial susceptibility of such microorganisms.

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14-02-2019 дата публикации

Method and Apparatus of Structured Illumination Digital Holography

Номер: US20190049896A1
Принадлежит:

A method of structured illumination digital holography includes: (a) providing a structured illumination generating unit and binarization random number encoding unit to generate a coded structured illumination pattern; (b) sampling at least two patterns with phase shift which synthesized as a single structured illumination pattern to be encoded; (c) forming a single digital hologram, and wavefront reconstructing the single digital hologram; (d) performing a compressive sensing approach to recover the object wave with at least two phase shift patterns; and (e) reconstructing the separation of overlap spectrum, to obtain an image covering bandpass spectrum with different high frequency and low frequency. 1. A method of structured illumination digital holography , comprising(a) providing a structured illumination generating unit and a binary random number encoding unit to generate a structured illumination pattern;(b) based-on at least two sheets of binary random number encoding patterns of said structured illumination pattern, sampling at least two sheets of patterns with phase shift to be synthesized as a single sheet of structured illumination pattern to be encoded;(c) interfering an encoded structured object wave with a reference wave to form a single sheet of digital hologram, and wavefront reconstructing said single sheet of digital hologram;(d) random number decoding said single sheet of digital hologram to extract object wave with corresponding original phase shift pattern, and performing an image processing approach to recover object wave with at least two sheets of phase shift patterns; and(e) reconstructing separation of overlap spectrum of said object wave with at least two sheets of phase shift patterns.2. The method of claim 1 , wherein said encoded structured object wave is formed by said single sheet of encoded structured illumination pattern illuminating an object.3. The method of claim 1 , wherein said random number decoding in said step (d) is binary ...

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14-02-2019 дата публикации

Image processing apparatus, method of image processing, and image processing system

Номер: US20190049897A1
Принадлежит: Sony Corp

There is provided an image processing apparatus including: a motion detector configured to detect motion of an observation target from a hologram of the observation target; a hologram processing unit configured to extract a portion of the hologram based on a result obtained by detecting the motion of the observation target; and a reconstruction unit configured to reconstruct an image from a portion of the extracted hologram.

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15-05-2014 дата публикации

HOLOGRAPHIC IMAGE GENERATION AND RECONSTRUCTION

Номер: US20140132710A1
Автор: Yamaichi Eiji
Принадлежит: EMPIRE TECHNOLOGY DEVELOPMENT LLC

Technologies are generally described for generating and recording holograms of an object using a plurality of light sources and an array of image sensors arranged to surround the object. In various examples, an apparatus may be configured to irradiate a plurality of light beams from multiple light sources to a corresponding number of beam splitters, which are configured to generate a first portion of the light beams that can be irradiated on the object, and a second portion of the light beams that can be reflected by a mirror unit to generate reference beams. Some apparatus can also include an array of image sensors that may be configured to receive images of interference caused by the reference beams and object beams scattered by the object. 1. A holographic image generating apparatus , comprising:a plurality of light sources, each configured to irradiate a light beam;a plurality of beam splitters, each configured to split the light beam irradiated from a corresponding one of the plurality of light sources into a first portion and a second portion of the light beam, wherein the first portion of the light beam is irradiated on an object;a mirror unit configured to receive the second portion of the light beams from the plurality of beam splitters, and reflect at least part of the second portions of the light beams to generate reference beams; andan array of image sensors arranged to substantially surround the object, the image sensors being configured to receive images of interference caused by the reference beams and the first portions of the light beams scattered by the object and convert the received images into image signals.2. The apparatus of claim 1 , further comprising a recording unit configured to record the image signals in a storage unit.3. The apparatus of claim 1 , further comprising a transmitting unit configured to transmit the image signals to a holographic image reconstruction apparatus.4. The apparatus of claim 1 , wherein the array of image ...

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02-03-2017 дата публикации

APPARATUS FOR HOLOGRAPHIC DISPLAY

Номер: US20170060088A1

Provided is a holographic display apparatus including a motor configured to synchronize with a hologram transmitted based on user's point of view and to rotate; a spatial light modulator configured to load hologram data generated based on the user's point of view in a fixed position state and to perform a light modulation; a mirror configured to provide the hologram which is light-modulated by the spatial light modulator according to the user's point of view during the rotation by rotation operation of the motor; and a hologram correction unit configured to compensate a rotation error between the fixed spatial light modulator and the rotating mirror and to provide a corrected hologram data to the spatial light modulator. 1. A holographic display apparatus comprising:a motor configured to synchronize with a hologram transmitted based on user's point of view and to rotate;a spatial light modulator configured to load hologram data generated based on the user's point of view in a fixed position state and to perform a light modulation;a mirror configured to provide the hologram which is light-modulated by the spatial light modulator according to the user's point of view during the rotation by rotation operation of the motor; anda hologram correction unit configured to compensate a rotation error between the fixed spatial light modulator and the rotating mirror and to provide a corrected hologram data to the spatial light modulator.2. The holographic display apparatus of claim 1 , wherein the spatial light modulator is separate from the motor or a rotation shaft of the motor.3. The holographic display apparatus of claim 1 , wherein one side of the mirror is fixed to a rotation shaft of the motor.4. The holographic display apparatus of claim 1 , wherein the mirror is fixed to a rotation shaft of the motor by a fixing means.5. The holographic display apparatus of claim 1 , wherein claim 1 , when correcting a three-dimensional object in a form of computer graphic (CG) claim ...

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22-05-2014 дата публикации

METHOD AND SYSTEM FOR DETECTING AND/OR CLASSIFYING CANCEROUS CELLS IN A CELL SAMPLE

Номер: US20140139625A1
Принадлежит: OVIZIO IMAGING SYSTEMS NV/SA

The current invention concerns a method for detecting cancerous cells and/or classifying cells in a cell sample comprising the following steps: providing a cell sample; obtaining holographic information from said cell sample by digital holographic microscopy (DHM); deriving at least one cellular parameter from said holographic information, and; classifying said cells of cells sample; characterized in that said classification occurs by appointing a Scoring Factor to said cells of cell sample, based on said cellular parameters. In a second aspect, a system for the detection of cancerous cells and/or classification of cells in a cell sample is provided, employing the method as disclosed in the invention. In a final aspect, a method for updating and/or improving a database comprising thresholds linked to holographic information and the database related thereof is equally disclosed. 2. A method according to claim 1 , wherein said at least one cellular parameter derived from obtained holographic information comprises the optical nuclear height.3. A method according to claim 1 , wherein said at least one cellular parameters derived from obtained holographic information comprise cell nucleus diameter claim 1 , chromatin texture claim 1 , cell size claim 1 , cell form and cell morphology.4. A method according to claim 1 , wherein image identification is linked to said cellular parameters and Scoring Factor derived thereof.5. A method according to claim 1 , wherein said appointed Scoring Factor is based upon comparison of said at least one cellular parameter and a threshold database.6. A method according to claim 5 , wherein said threshold database is stored on an internal or external server.7. A method according to claim 6 , wherein said Scoring Factors are appointed by use of queries on said server.8. A method according to claim 5 , further comprising the step of providing a practitioner with a digital report comprising Scoring Factors and classification of said cells in ...

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20-02-2020 дата публикации

OPTICAL IMAGING WITH ULTRASONIC SIGNAL

Номер: US20200059611A1
Принадлежит:

An imaging system includes an infrared illuminator, an ultrasonic emitter, a reference wavefront generator, and an image pixel array. The infrared illuminator emits a general illumination emission into a three-dimensional diffuse medium, where a portion of the general illumination emission encounters a voxel within the diffuse medium. The ultrasonic emitter focuses an ultrasonic signal to the voxel to wavelength-shift the portion of the general illumination emission to generate a shifted infrared imaging signal. The reference wavefront generator generates an infrared reference wavefront having a same wavelength as the shifted infrared imaging signal. The image pixel array captures an infrared image of an interference between the shifted infrared imaging signal and the infrared reference wavefront. 1. An imaging system , comprising:an infrared illuminator configured to emit a general illumination emission into a three-dimensional diffuse medium;an ultrasonic emitter configured to focus an ultrasonic signal to a voxel within the three-dimensional diffuse medium to wavelength-shift a portion of the general illumination emission that encounters the voxel to generate a shifted infrared imaging signal;a reference wavefront generator configured to generate an infrared reference wavefront having a same wavelength as the shifted infrared imaging signal; andan image pixel array configured to receive at least a portion of the shifted infrared imaging signal and a portion of the infrared reference wavefront to capture an infrared image of an interference between the shifted infrared imaging signal and the infrared reference wavefront.2. The imaging system of claim 1 , wherein the infrared illuminator includes an infrared laser that generates the general illumination emission of coherent infrared light.3. The imaging system of claim 2 , wherein the coherent infrared light is monochromatic coherent infrared light.4. The imaging system of claim 1 , wherein the general illumination ...

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17-03-2022 дата публикации

Image processing apparatus, evaluation system, image processing program, and image processing method

Номер: US20220083004A1
Принадлежит: Fujifilm Corp

An image processing apparatus includes an acquisition unit that acquires a hologram obtained by imaging a plurality of granules contained within an imaging visual field, a generation unit that generates, from the hologram, phase difference images at positions different from each other in an optical axis direction in a case in which the hologram is captured, a specifying unit that specifies a plurality of image ranges in a direction of a plane intersecting the optical axis direction, which correspond to the plurality of granules, in an averaged image obtained by averaging at least some of the phase difference images, and an extraction unit that extracts the phase difference image at a center position of a corresponding granule in the optical axis direction for each of the plurality of image ranges.

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28-02-2019 дата публикации

Focusing light inside scattering media with magnetic particle guided wavefront shaping

Номер: US20190064736A1

A magnetic field controlled guidestar for focusing light deep inside scattering media using optical phase conjugation. Compared with the optical and ultrasonic field, the magnetic field has an exceptional penetration depth. The magnetic particle guidestar has a high light-tagging efficiency, good biocompatibility, and a small diameter which enables a sharp and bright focusing deep inside biological tissue. This new method can benefit a wide range of biomedical applications including deep-tissue imaging, neural modulation, and targeted photothermal and photodynamic therapies.

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28-02-2019 дата публикации

OPTICAL MODULATION METHOD, OPTICAL MODULATION DEVICE AND HOLOGRAPHIC DISPLAY APPARATUS

Номер: US20190064737A1
Автор: SHI Bingchuan
Принадлежит:

The present disclosure provides an optical modulation device, an optical modulation method and a holographic display apparatus. The optical modulation device is configured to perform optical modulation of a light beam and comprising: an amplitude modulator, configured to perform amplitude modulation of the light beam based on amplitude information in complex amplitude information of each pixel of a digital hologram; an optical scanning assembly, configured to scan the light beam within a predetermined range; a phase modulator, configured to perform phase modulation of the light beam based on phase information in the complex amplitude information. 1. An optical modulation device , configured to perform optical modulation of a light beam and comprising:an amplitude modulator, configured to perform amplitude modulation of the light beam based on amplitude information in complex amplitude information of each pixel of a digital hologram;an optical scanning assembly, configured to scan the light beam within a predetermined range;a phase modulator, configured to perform phase modulation of the light beam based on phase information in the complex amplitude information.2. The optical modulation device according to claim 1 , wherein one of the amplitude modulator and the phase modulator further includes:a light source, configured to generate the light beam.3. The optical modulation device according to claim 1 , wherein the optical scanning assembly is configured to scan the light beam corresponding to each pixel according to a position of respective pixel in the digital hologram.4. The optical modulation device according to claim 3 , wherein the optical scanning assembly includes:a micromirror, configured to rotate a corresponding deflection angle according to a position of each pixel in the digital hologram, and to reflect the light beam;a lens assembly, configured to output the light beam from the micromirror along a direction parallel to an optical axis of the lens ...

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15-03-2018 дата публикации

Imaging with Infrared Imaging Signals

Номер: US20180070891A1
Автор: Jepsen Mary Lou
Принадлежит:

An infrared imaging signal is generated. An image of an exit signal of the infrared imaging signal is captured. The infrared imaging signal is within a frequency band. 1. An imaging device comprising:an emitter for emitting infrared light within a frequency band;a display pixel array including a plurality of pixels, each pixel in the plurality of pixels is individually configurable to modulate an amplitude of the infrared light received from the emitter to generate an infrared holographic imaging signal according to a holographic pattern driven onto the display pixel array; andan image pixel array including a plurality of imaging pixels configured to receive incident light within the frequency band and reject light outside of the frequency band.2. The imaging device of further comprising:a reference wavefront generator configured to illuminate the image pixel array with a reference wavefront in response to receiving an activation signal, the reference wavefront generator to illuminate the image pixel array during a time period overlapping with a capturing of an infrared image by the image pixel array, wherein the reference wavefront is within the frequency band.3. The imaging device of claim 2 , wherein the reference wavefront generator receives the infrared light from the emitter claim 2 , and wherein the emitter is a laser and the frequency band is monochromatic infrared light.4. The imaging device of further comprising:a directional ultrasonic emitter configured to dynamically focus an ultrasonic signal to a given voxel in three-dimensional space, wherein the directional ultrasonic emitter is configured to focus the ultrasonic signal to a first voxel in three-dimensional space while the holographic pattern is driven onto the display pixel array and while an infrared image is captured with the image pixel array.5. The imaging device of claim 1 , wherein the image pixel array is positioned to image an exit signal generated by the infrared holographic imaging signal ...

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07-03-2019 дата публикации

Applications of diffuse medium imaging

Номер: US20190072897A1
Принадлежит: Open Water Internet Inc

Methods and apparatus are configured for focusing and imaging of translucent materials with decreased size and complexity and improve resolution. The methods and apparatus provide improved focusing and imaging with decreased size and weight, so as to allow use in many fields.

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07-03-2019 дата публикации

FULL-COLOR INCOHERENT DIGITAL HOLOGRAPHY

Номер: US20190072898A1
Автор: Kim Myung K.
Принадлежит: UNIVERSITY OF SOUTH FLORIDA

In one embodiment, a digital holography system includes logic configured to receive raw interferograms obtained by illuminating an object field with incoherent light, the raw interferograms comprising multiple phase-shifted raw interferograms for each of multiple different colors, logic configured to combine like-colored raw interferograms to generate a separate complex hologram for each different color, logic configured to combine the separate complex holograms to generate a full-color complex hologram, and logic configured to reconstruct a full-color holographic image of the object field. 1. A non-transitory computer-readable medium that stores a digital holography system , the digital holography system comprising:logic configured to receive raw interferograms obtained by illuminating an object field with incoherent light, the raw interferograms comprising multiple phase-shifted raw interferograms for each of multiple different colors;logic configured to combine like-colored raw interferograms to generate a separate complex hologram for each different color;logic configured to combine the separate complex holograms to generate a full-color complex hologram; andlogic configured to reconstruct a full-color holographic image of the object field.2. The non-transitory computer-readable medium of claim 1 , wherein the logic configured to receive raw interferograms is configured to receive at least six phase-shifted raw interferograms for each color.3. The non-transitory computer-readable medium of claim 1 , wherein the logic configured to receive raw interferograms is configured to receive multiple phase-shifted raw interferograms for each of three different colors.4. The non-transitory computer-readable medium of claim 1 , wherein the logic configured to receive raw interferograms is configured to receive multiple phase-shifted red raw interferograms claim 1 , multiple phase-shifted green raw interferograms claim 1 , and multiple phase-shifted blue raw interferograms.5 ...

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05-03-2020 дата публикации

DEVICE AND METHOD FOR BIMODAL OBSERVATION OF AN OBJECT

Номер: US20200072728A1
Принадлежит:

A device including a light source, an image sensor, and a holder defining two positions between the light source and the image sensor. Each position is able to receive an object with a view to its observation. An optical system is placed between the two positions. Thus, when an object is placed in a first position, it may be observed, through the optical system, via a conventional microscopy modality. When an object is placed in the second position, it may be observed via a second lensless imagery modality. 116-. (canceled)17. A device for observing an object , comprising:a light source and an image sensor, the light source being configured to emit an emission wave, along an emission axis, so that the light wave propagates, along an optical path, toward the image sensor, through the object;an optical system that is placed, on the optical path, between the light source and the image sensor; the first position is interposed, on the optical path, between the light source and the optical system, the optical system configured to conjugate the image sensor to the first position; and', 'the second position is interposed, on the optical path, between the optical system and the image sensor, such that there is no magnifying optics between the second position and the image sensor., 'a holder that defines a first position and a second position, each position being configured to receive the object, the holder being configured such that18. The device of claim 17 , wherein the optical path lies parallel to the emission axis so that the light source claim 17 , the optical system claim 17 , and the image sensor are aligned along the emission axis claim 17 , the holder configured such that the first position and the second position are aligned along the emission axis.19. The device of claim 18 , wherein the holder is translationally movable in a direction that is perpendicular to the emission axis.20. The device of claim 17 , further comprising a first mirror placed claim 17 , along ...

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18-03-2021 дата публикации

PORTABLE DIFFRACTION-BASED IMAGING AND DIAGNOSTIC SYSTEMS AND METHODS

Номер: US20210080390A1
Принадлежит:

The disclosure features systems and methods for measuring and diagnosing target constituents bound to labeling particles in a sample. The systems include a radiation source, a sample holder, a detector configured to obtain one or more diffraction patterns of the sample each including information corresponding to optical properties of sample constituents, and an electronic processor configured to, for each of the one or more diffraction patterns: (a) analyze the diffraction pattern to obtain amplitude information and phase information corresponding to the sample constituents; (b) identify one or more particle-bound target sample constituents based on at least one of the amplitude information and the phase information; and (c) determine an amount of at least one of the particle-bound target sample constituents in the sample based on at least one of the amplitude information and the phase information. 1. A diagnostic system for measuring target constituents bound to labeling particles in a sample , the system comprising:a radiation source configured to generate illumination radiation;a sample holder configured to support the sample so that the sample is exposed to the illumination radiation;a detector configured to obtain one or more diffraction patterns of the sample, wherein each of the diffraction patterns comprises information corresponding to optical properties of sample constituents; and (a) analyze the diffraction pattern to obtain amplitude information and phase information corresponding to the sample constituents;', '(b) identify one or more particle-bound target sample constituents based on at least one of the amplitude information and the phase information; and', '(c) determine an amount of at least one of the particle-bound target sample constituents in the sample based on at least one of the amplitude information and the phase information., 'an electronic processor configured to, for each of the one or more diffraction patterns2. The system of claim 1 , ...

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18-03-2021 дата публикации

SUPER-RESOLUTION HOLOGRAPHIC MICROSCOPE

Номер: US20210080743A1
Принадлежит: SAMSUNG ELECTRONICS CO., LTD.

Provided is a super-resolution holographic microscope including a light source configured to emit input light, a diffraction grating configured to split the input light into first diffracted light and second diffracted light, a mirror configured to reflect the first diffracted light, a wafer stage arranged on an optical path of the second diffracted light and on which a wafer is configured to be arranged, and a camera configured to receive the first diffracted light that is reflected by the mirror and the second diffracted light that is reflected by the wafer to generate a plurality of hologram images of the wafer. 1. A super-resolution holographic microscope comprising:a light source configured to emit input light;a diffraction grating configured to split the input light into first light and second light;a mirror configured to reflect the first light;a wafer stage arranged on an optical path of the second light and on which a wafer is configured to be arranged; anda camera configured to receive the first light reflected by the mirror and the second light reflected by the wafer to generate a plurality of hologram images of the wafer.2. The super-resolution holographic microscope of claim 1 , wherein the input light is directly incident on the diffraction grating.3. The super-resolution holographic microscope of claim 1 , wherein the first light provided from the diffraction grating is directly incident on the mirror.4. The super-resolution holographic microscope of claim 1 , wherein the second light provided from the diffraction grating is directly incident on the wafer.5. The super-resolution holographic microscope of claim 1 , wherein the diffraction grating is a transmissive-type.6. The super-resolution holographic microscope of claim 1 , wherein the diffraction grating is a reflective-type.7. The super-resolution holographic microscope of claim 1 , wherein the first light is zeroth-order diffracted light.8. The super-resolution holographic microscope of claim 1 ...

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26-03-2015 дата публикации

HOLOGRAPHIC IMAGE GENERATION AND RECONSTRUCTION

Номер: US20150085069A1
Автор: Yamaichi Eiji
Принадлежит:

Technologies are generally related to holographic imaging. In some examples, techniques are described for generating a holographic image of an object using a plurality of light sources, a shutter, and an image sensor array. Each of the light sources is configured to generate a light beam using a respective wavelength in a different range. In various examples, an apparatus as described here may be configured to control the shutter to receive the light beams from the plurality of light sources and selectively pass each of the received light beams to provide a selected light beam. The apparatus may further include a beam splitter and a mirror unit configured to generate an object light beam and a reference light beam from the selected light beam. The apparatus may include an image sensor array configured to detect an image of interference caused by the reference light beam and the object light beam. 1. An apparatus configured to generate a holographic image of an object , the apparatus comprising:a plurality of light sources, each configured to generate a light beam corresponding to a wavelength in a different range;a shutter configured to receive the light beams from the plurality of light sources and selectively pass each of the received light beams in turn to provide a selected light beam;a beam splitter configured to split the selected light beam into a first light beam and a second light beam, wherein the beam splitter is also configured to irradiate the first light beam on the object such that at least part of the first light beam is scattered by the object to generate an object light beam;a mirror unit configured to receive the second light beam from the beam splitter, and return at least part of the second light beam as a reference light beam;an image sensor array configured to receive the reference light beam and the object light beam, and also configured to detect an image of interference caused by the reference light beam and the object light beam, wherein ...

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24-03-2016 дата публикации

APPARATUS AND METHOD FOR DISPLAYING HOLOGRAPHIC THREE-DIMENSIONAL IMAGE

Номер: US20160085211A1
Принадлежит: SAMSUNG ELECTRONICS CO., LTD.

Provided are an apparatus and a method for displaying a holographic three-dimensional (3D) image. The apparatus includes an image segmenter configured to segment an original image into a plurality of segments, and a calculator configured to calculate diffraction fringe pattern information for displaying each of the plurality of segments as a 3D holographic image. The image segmenter adjusts the number of the plurality of segments. 1. An apparatus for displaying a holographic three-dimensional (3D) image , the apparatus comprising:an image segmenter configured to segment an original image into a plurality of segments, and adjust a number of the segments per unit volume or the number of the segments per unit area;a calculator configured to calculate diffraction fringe pattern information for displaying each of the plurality of segments as a 3D holographic image; anda light modulator configured to form a diffraction fringe pattern according to the diffraction fringe pattern information and generate the 3D holographic image corresponding to the original image by modulating a light incident on the diffraction fringe pattern.2. The apparatus of claim 1 , wherein the image segmenter is further configured to adjust the number of the segments according to at least one selected from a shape of an object included in the original image claim 1 , a position of the object included in the original image claim 1 , and a property of a light representing the original image.3. The apparatus of claim 2 , wherein the property of the light representing the original image includes at least one selected from a brightness of the light and a wavelength of the light.4. The apparatus of claim 1 , wherein the image segmenter is further configured to segment the original image by using at least one selected from a mode of segmenting the original image into a plurality of layers according to a depth of the original image claim 1 , a mode of segmenting the original image into a plurality of points ...

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23-03-2017 дата публикации

LENSLESS IMAGING DEVICE AND ASSOCIATED METHOD OF OBSERVATION

Номер: US20170082975A1

The invention describes a device allowing the observation of a sample, comprising particles, for example biological particles, by lensless imaging. The sample is disposed against a substrate, the substrate being interposed between a light source and an image sensor. The substrate comprises at least one thin film, extending across a thin film plane, structured so as to form a diffraction grating, designed to confine a part of a light wave emitted by the light source, in a plane parallel to said thin film plane. The device does not comprise magnification optics between the substrate and the image sensor. 1. A device for forming an image of a sample comprising:a light source, configured to emit a light wave, referred to as incident wave, at a wavelength, along an axis of propagation, toward the sample;an image sensor;a substrate, configured to receive the sample, disposed between the light source and the image sensor;the substrate comprising a first thin film, comprising a first material, transparent at said wavelength, with a first refractive index, extending across a plane, referred to as plane of the thin film,said first thin film comprising a plurality of inclusions, formed from a second material, transparent at said wavelength, with a second refractive index;the distance between two adjacent inclusions being less than said wavelength;said inclusions defining a first bi-dimensional diffraction grating, within said first thin film, designed to confine a part of the incident wave across a plane parallel to said thin film plane;the device not comprising magnification optics between the substrate and the image sensor.2. The device as claimed in claim 1 , in which the first diffraction grating is designed for generating a resonant reflection of the incident wave at said wavelength so as to reflect a part of said incident light wave toward the light source.3. The device as claimed in claim 1 , in which claim 1 , the substrate being bounded by a lower face and an upper ...

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31-03-2022 дата публикации

ATTENUATING WAVEFRONT DETERMINATION FOR NOISE REDUCTION

Номер: US20220101807A1
Принадлежит:

A system and method comprise a light source; a spatial light modulator including a substantially transparent material layer and a phase modulation layer; an imaging device configured to receive a light from the light source as reflected by the spatial light modulator, and to generate an image data; and a controller. The controller provides a phase-drive signal to the spatial light modulator and determines an attenuating wavefront of the substantially transparent material layer based on the image data. 126-. (canceled)27. A projector system , comprising:a light source;a spatial light modulator including a substantially transparent material layer and a phase modulation layer, wherein the substantially transparent material layer is a cover glass having a transmissivity of 90% or greater;an imaging device configured to receive a light from the light source as reflected by the spatial light modulator, and to generate an image data, wherein the image data includes a first component corresponding to a portion of the light reflected by the substantially transparent material layer and a second component corresponding to a portion of the light reflected by the phase modulation layer; and{'claim-text': ['provide a phase-drive signal to the spatial light modulator for producing a reconstruction of the image data that is at least reduced in noise introduced by the substantially transparent material layer, and', 'determine an attenuating wavefront of the substantially transparent material layer based on the image data by using phase-shifting holography,'], '#text': 'a controller configured to:'}wherein the controller is further configured to:compute a plurality of attenuating wavefront candidates, and to select, as the attenuating wavefront, the attenuating wavefront candidate that yields a reconstruction having a smallest noise effect from among the plurality of attenuating wavefront candidates, andtune the phase-drive signal based on the attenuating wavefront.28. The system ...

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21-03-2019 дата публикации

DIGITAL HOLOGRAPHIC IMAGING APPARATUS

Номер: US20190086864A1
Автор: WATANABE Satoshi
Принадлежит: OLYMPUS CORPORATION

An illumination unit emits illumination light to a specimen. An image sensor includes multiple pixels arranged in a two-dimensional manner on a photoelectric surface. The image sensor captures an image of a magnitude distribution of an interference pattern formed due to the illumination light that has interacted with the specimen. A limiter limits at least one from among the spatial frequency of the interference pattern formed on the photoelectric surface and the incident angle of the light input to the photoelectric surface. 1. A digital holographic imaging apparatus comprising:an illumination unit structured to emit an illumination light to a specimen;an image sensor comprising a plurality of pixels arranged on a photoelectric surface thereof in a two-dimensional manner, and structured to capture an image of a magnitude distribution of an interference pattern generated due to the illumination light that has interacted with the specimen; anda limiter structured to limit at least one from among a spatial frequency of the interference pattern formed on the photoelectric surface and an incident angle at which the light is input to the photoelectric surface.2. The digital holographic imaging apparatus according to claim 1 , wherein the limiter is arranged between the specimen and the photoelectric surface.3. The digital holographic imaging apparatus according to claim 1 , wherein claim 1 , with a pixel pitch of the image sensor as p claim 1 , the limiter is structured to allow a spatial frequency component that is equal to or lower than (½·p) to pass through.4. The digital holographic imaging apparatus according to claim 1 , wherein the limiter comprises an incident angle limiter structured to limit the incident angle at which the light is input to the photoelectric surface.5. The digital holographic imaging apparatus according to claim 4 , wherein the incident angle limiter is formed within the image sensor.6. The digital holographic imaging apparatus according to ...

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21-03-2019 дата публикации

DIGITAL HOLOGRAPHIC IMAGING APPARATUS

Номер: US20190086865A1
Автор: Matsuo Keigo
Принадлежит: OLYMPUS CORPORATION

An illumination unit emits an illumination light to a specimen. An image sensor includes multiple pixels arranged in a two-dimensional manner. The image sensor captures an image of the intensity distribution of an interference pattern formed due to the illumination light that has interacted with the specimen, and outputs image data. A defect information acquisition unit acquires defect position information that indicates the positions of defective pixels of the image sensor. A processing unit reconstructs a subject image that represents the specimen based on the image data and the defect position information. 1. A digital holographic imaging apparatus comprising:an illumination unit structured to emit an illumination light to a specimen;an image sensor comprising a plurality of pixels arranged in a two-dimensional manner, and structured to capture an image of an intensity distribution of an interference pattern formed due to the illumination light that has interacted with the specimen, and to output image data;a defect information acquisition unit structured to acquire defect position information that indicates a position of a defective pixel of the image sensor; anda processing unit configured to reconstruct a subject image that represents the subject based on the image data and the defect position information.2. The digital holographic imaging apparatus according to claim 1 , wherein the processing unit uses the defect position information in an iterative calculation loop for reconstructing the subject image.3. The digital holographic imaging apparatus according to claim 1 , wherein the defect information acquisition unit comprises a defect position storage unit structured to store the position of a defective pixel specified before measurement of the specimen.4. The digital holographic imaging apparatus according to claim 1 , wherein the defect information acquisition unit specifies the positions of defective pixels based on an output of the image sensor.5. The ...

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21-03-2019 дата публикации

DEVICE AND METHOD FOR ACQUIRING A PARTICLE PRESENT IN A SAMPLE

Номер: US20190086866A1
Автор: Douet Alice, Josso Quentin
Принадлежит:

A device for acquisition of particles present in a sample includes a spatially coherent light source, an optical system, and an image sensor placed in the focal plane of the optical system. The image sensor is configured to capture an intensity image. A computational unit of the device is configured to construct a series of electromagnetic propagation matrices obtained for a plurality of defocusing offsets relative to a plane of focus of the optics. The computational unit is also configured to determine a first average focused electromagnetic matrix for the particles from the series of electromagnetic matrices, identifying at least one of the particles in the first electromagnetic matrix and storing the coordinates of said particle, and determining a second electromagnetic matrix at a distance of focus on a particle identified from the components of the series of electromagnetic matrices having the stored coordinates. 1. A device of acquisition of a plurality of particles present in a sample , said acquisition device comprising:a spatially coherent or pseudo-coherent light source directed towards a first surface of said sample;an optical system having an optical axis and achieving the conjugation between a plane of focus and a focal plane, directed towards a second surface of said sample opposite to said first surface, and placed relative to the sample so that the particles are not in the plane of focus;an image sensor placed in the focal plane of the optical system and configured to acquire an intensity image (Ih) formed by the interference between said light source and said sample; and [{'b': '1', 'a unit of digital construction of a series of electromagnetic matrices (I-IN) modeling, from the acquired image (Ih), the electromagnetic wave in planes parallel to the plane of focus and comprised in the sample for a plurality of offsets relative to said plane,'}, {'b': '1', 'a unit for determining a first electromagnetic matrix (Ifmoy) at an average distance of focus ...

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21-03-2019 дата публикации

ANALYZING DIGITAL HOLOGRAPHIC MICROSCOPY DATA FOR HEMATOLOGY APPLICATIONS

Номер: US20190087638A1
Принадлежит:

A method for analyzing digital holographic microscopy (DHM) data for hematology applications includes receiving a plurality of DHM images acquired using a digital holographic microscopy system. One or more connected components are identified in each of the plurality of DHM images and one or more training white blood cell images are generated from the one or more connected components. A classifier is trained to identify a plurality of white blood cell types using the one or more training white blood cell images. The classifier may be applied to a new white blood cell image to determine a plurality of probability values, each respective probability value corresponding to one of the plurality of white blood cell types. The new white blood cell image and the plurality of probability values may then be presented in a graphical user interface. 1. A method for analyzing digital holographic microscopy (DHM) data for hematology applications to perform white blood cell differentiation , the method comprising:receiving a plurality of DHM images acquired using a digital holographic microscopy system;identifying one or more connected components in each of the plurality of DHM images;generating one or more training white blood cell images from the one or more connected components;training a classifier to identify a plurality of white blood cell types using the one or more training white blood cell images as an input to the classifier;extracting a new white blood cell image from a new DHM image;applying the classifier to the new white blood cell image to determine a plurality of probability values, each respective probability value corresponding to one of the plurality of white blood cell types; andpresenting the new white blood cell image and the plurality of probability values in a graphical user interface.2. The method of claim 1 , further comprising:prior to identifying the one or more connected components, applying a thresholding to the each of the plurality of DHM images to ...

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05-05-2022 дата публикации

SYSTEM AND METHOD FOR LIGHTFIELD CAPTURE

Номер: US20220137555A1
Автор: Hornstein Alex, Moore Evan
Принадлежит:

A system for generating holographic images or videos comprising a camera array, a plurality of processors, and a central computing system. A method for generating holographic images can include receiving a set of images and processing the images.

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09-04-2015 дата публикации

INTERFEROMETRIC SPATIAL LIGHT MODULATOR FOR PRODUCTION OF DIGITAL HOLOGRAMS

Номер: US20150098066A1
Автор: Jurbergs David
Принадлежит:

A digital holographic apparatus, system, and method are disclosed. The apparatus includes an electronic display device comprising an interferometric spatial light modulator based display engine and a processor coupled to the electronic display device. The processor is operative to upload digital content to the electronic display device. The digital content is displayed on the electronic display device and is recorded into a holographic medium when the holographic medium and the electronic display device are flood exposed by a laser generated light beam. The system additionally includes at least one laser coupled optically coupled to the electronic display device and communicatively coupled to the processor. A method of recording a digital hologram in a holographic medium using the digital holographic system also is disclosed. 1. A digital holographic apparatus , comprising:an electronic display device comprising an interferometric spatial light modulator based display engine; anda processor coupled to the electronic display device, wherein the processor is operative to upload digital content to the electronic display device,wherein the digital content is displayed on the electronic display device and is recorded into a holographic medium when the holographic medium and the electronic display device are flood exposed by a laser generated light beam.2. The digital holographic apparatus according to further comprising at least one laser optically coupled to the electronic display device claim 1 , wherein the at least one laser is configured to generate the light beam to flood expose the holographic medium and the electronic display device.3. The digital holographic apparatus according to claim 2 , wherein the processor is communicatively coupled to the at least one laser claim 2 , wherein the processor is operative to control the at least one laser to any one of an on position to flood expose the electronic display device and an off position to stop the flood exposure. ...

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19-03-2020 дата публикации

PROJECTION SYSTEM FOR MEASURING VIBRATIONS

Номер: US20200089164A1
Принадлежит:

A system for measuring vibrations of a surface (VSURF) of a mechanical part (M), comprising a source (SOURCE) of radiation (L), a first separator element (ELI) configured to define a first incident ray (LB) and a reference ray (RLB), a shaping module (DOEM) producing a second incident ray (LB) from said first incident ray (LB), and an optical element (OE) capable of an interferential addition of the reference ray (RLB) and a ray produced by a reflection of said second incident ray (LB) on said surface (VSURF), the shaping module (DOEM) comprising one or more diffracting optical elements (DOE DOEn), each comprising at least one diffraction structure (FSTRUCT) diffracting all or part of the first incident ray (LB) so as to illuminate a chosen surface of the mechanical part. 1. System (SYS) for measuring vibrations of a surface (VSURF) of a mechanical part (M) , by digital holography , said system comprising:a source (SOURCE) of radiation (L) emitting in a predetermined range (LF) of frequencies,{'b': 1', '1, 'a first separator element (EL) configured to define a first incident ray (LB) and a reference ray (RLB),'}{'b': 2', '1, 'a module (DOEM) for shaping a second incident ray (LB) from said first incident ray (LB), and'}{'b': 2', '2, 'an optical element (OE) configured to make said reference ray (RLB) and a radiation (LB′) produced by a reflection of said incident ray (LB) on said surface (VSURF) of said mechanical part (M) interfere,'}{'b': 2', '1', '1, 'said module (DOEM) for shaping said second incident ray (LB) comprises one or more diffracting optical elements (DOE, . . . , DOEn), each comprising at least one diffraction structure (FSTRUCT) configured to diffract all or part of said incident radiation (LB),'}said system being characterised in that said at least one diffraction structure is produced from a polymer, sol-gel or photoresin material resting against a glass substrate, said structure comprising elements etched in a plane parallel and/or orthogonal to ...

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19-03-2020 дата публикации

Interference Optics for Optical Imaging Device

Номер: US20200089165A1
Принадлежит:

A device includes a sensor, a coherent infrared illumination source and optics to direct an infrared reference beam to the sensor. The sensor is positioned to capture an image of an interference signal generated by an interference of the infrared reference beam and a wavelength-shifted exit signal. The wavelength-shifted exit signal propagates through the optics before interfering with the infrared reference beam. 1. A device comprising:a sensor for measuring an infrared interference pattern;a coherent infrared illumination source configured to emit an infrared reference beam; andan optical structure configured to receive a wavelength-shifted exit signal, wherein the optical structure includes a partially reflective layer disposed on a curvature, and wherein the partially reflective layer redirects the infrared reference beam to the sensor,wherein the infrared interference pattern is generated by the wavelength-shifted exit signal interfering with the infrared reference beam, and wherein the wavelength-shifted exit signal encounters the partially reflective layer prior to becoming incident on the sensor.2. The device of claim 1 , wherein the curvature that the partially reflective layer is disposed on is a parabolic curvature.3. The device of claim 2 , wherein the parabolic curvature is configured to collimate the infrared reference beam and direct rays of the infrared reference beam to the sensor at an angle to a vector that is normal to a pixel plane of the sensor.4. The device of claim 3 , wherein the angle is between 4 and 8 degrees.5. The device of further comprising:an infrared filtering layer, wherein the partially reflective layer is disposed between the infrared filtering layer and the sensor, and wherein the infrared filtering layer is configured to pass a wavelength band of the wavelength-shifted exit signal and reject other light wavelengths.6. The device of claim 5 , wherein the infrared filtering layer is an angle-selective infrared filtering layer ...

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16-04-2015 дата публикации

VOLUME HOLOGRAPHIC IMAGING SYSTEM (VHIS) ENDOSCOPE

Номер: US20150103140A1

Provided are modular volume holographic imaging system (VHIS) endoscopic systems, comprising: an endoscope attachment module having a microscope objective lens, a single or cascaded compensated relay system configured to preserve an optical wavefront for use with a single or multiplexed volume hologram to select wavefronts originating from different object depths, and a system aperture; and a handle module configured to be reversibly attachable for operative communication with the endoscope attachment module, and having a beam splitter; a relay having adjustable spacing for object space focus compensation, and a single or multiplexed volume hologram suitable in operation to select wavefronts originating from different object depths, and wherein the handle module is further configured for operative communication with an illumination source and imaging optics. Preferably, an illumination module and an imaging module are configured to be in operative, reversibly attachable communication with the handle module. Flexible tip endoscopic embodiments are provided. 1. A modular volume holographic imaging system (VHIS) endoscopic system , comprising: an observing end and a distal attachment end,', 'a microscope objective lens positioned at the observing end,', 'a single or cascaded compensated relay system having one or a plurality of pupil relays positioned between the objective lens and the distal attachment end and configured to preserve an optical wavefront for use with a single or multiplexed volume hologram to select wavefronts originating from different object depths, and', 'a system aperture with pupil positioned between the objective lens and the one or the plurality of pupil relays; and, 'an endoscope attachment module having'} a beam splitter,', 'a relay having adjustable spacing for object space focus compensation, and', 'a single or multiplexed volume hologram suitable in operation to select wavefronts originating from different object depths, and wherein the ...

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12-05-2022 дата публикации

DEVICE FOR HYPERSPECTRAL HOLOGRAPHIC MICROSCOPY BY SENSOR FUSION

Номер: US20220146981A1
Автор: GERMAIN Gérald
Принадлежит: LYSIA

The invention concerns a device for the holographic and hyperspectral measurement and analysis () of a sample (), comprising; —an acquisition means () for acquiring a diffracted image () of an image of the sample (); and interference patterns () of a reference light signal (R) and the light signal (O) having passed through the sample () to be measured and analysed; and—a means for illuminating the sample () focused on the sample (); and—a means for reconstructing and analysing () the hyperspectral holographic image comprising a deep convolutional neural network generating an image for analysis and detection of particularities in the sample. 1. Device for holographic and hyperspectral measuring and analyzing of a sample , wherein said device comprises:an acquisition device of an image containing spectral and amplitude information of the light signal illuminating said sample; and holographic interference figures of a reference light bear and of a light beam having illuminated said sample containing the amplitude and phase information of the light signal illuminating said sample; andan illumination device of said sample; anda device for reconstructing the hyperspectral holographic image and analyzing the amplitude, phase and spectrum properties of the light illuminating said sample integrating a deep and convolutional neural network architectured for calculating a probability of presence of the particularity sought in said sample from the hyperspectral holographic image, and generating an image for each sought particularity whose value of each pixel at the x and y coordinates corresponds to the probability presence of said particularity at the same x and y coordinates of said sample.2. Device according to claim 1 , in which the acquisition device comprises a device for acquiring a compressed image of the sample containing said spectral and amplitude information of the illuminating light signal claim 1 , and a device for acquiring an image of said holographic ...

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14-04-2016 дата публикации

HOLOGRAPHIC DISPLAY APPARATUS AND HOLOGRAPHIC DISPLAY METHOD

Номер: US20160103321A1
Принадлежит: SAMSUNG ELECTRONICS CO., LTD.

A holographic display apparatus includes a spatial light modulator configured to generate hologram patterns to modulate light; an illuminator configured to emit the light to the spatial light modulator; and a controller configured to control operations of the spatial light modulator and the illuminator, the spatial light modulator being configured to generate, from among the hologram patterns, a first hologram pattern and a second hologram pattern according to the control operations of the controller, the first hologram pattern and the second hologram pattern being configured to form a first hologram image and a second hologram image having different viewpoints, and the controller being configured to set a first phase modulation value of the first hologram pattern and a second phase modulation value of the second hologram pattern to be different from each other such that hologram images having different viewpoints are formed. 1. A holographic display apparatus comprising:a spatial light modulator configured to generate hologram patterns to modulate light;an illuminator configured to emit the light to the spatial light modulator; anda controller configured to control operations of the spatial light modulator and the illuminator,wherein the spatial light modulator is configured to generate, from among the hologram patterns, a first hologram pattern and a second hologram pattern according to the control operations of the controller, the first hologram pattern and the second hologram pattern being configured to form a first hologram image and a second hologram image having different viewpoints, andwherein the controller is configured to set a first phase modulation value of the first hologram pattern and a second phase modulation value of the second hologram pattern to be different from each other such that hologram images having different viewpoints formed by the first hologram pattern and the second hologram pattern are formed on different spatial locations.2. The ...

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14-04-2016 дата публикации

APPARATUS AND METHOD FOR DIGITAL HOLOGRAPHIC TABLE TOP DISPLAY

Номер: US20160105658A1
Принадлежит:

Disclosed is an apparatus and method for digital holographic table top display. The digital holographic table top display apparatus includes: a camera array configured to capture a plurality of channel images in an omni-directional range from a table by using a plurality of cameras; a controller configured to detect an observer from the plurality of channel images and to track a position of pupils of the observer in at least one channel image from which the observer is detected; and a display configured to reproduce a digital holographic image in a three-dimensional (3D) space according to the tracked position of the pupils. 1. A digital holographic table top display apparatus , comprising:a camera array configured to capture a plurality of channel images in an omni-directional range from a table by using a plurality of cameras;a controller configured to detect an observer from the plurality of channel images and to track a position of pupils of the observer in at least one channel image from which the observer is detected; anda display configured to reproduce a digital holographic image in a three-dimensional (3D) space according to the tracked position of the pupils.2. The apparatus of claim 1 , wherein the camera array of the plurality of cameras is arranged in a circle toward a center of the table to acquire images around 360 degrees.3. The apparatus of claim 1 , wherein the controller comprises:a multi-grid image generator configured to combine the channel images captured by the plurality of cameras to generate one multi-grid image;an observer detector configured to detect at least one observer from the multi-grid image;a channel determiner configured to select a channel associated with a channel image from which the observer is detected;a pupil tracker configured to track the position of the pupils in the channel image associated with information on the selected channel; anda coordinate calculator configured to calculate 3D coordinates of the position of the ...

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26-03-2020 дата публикации

Cell observation device

Номер: US20200096940A1
Принадлежит: Shimadzu Corp

In a microscopic observation unit ( 10 ), hologram data is acquired at each measurement position on a cell culture plate ( 13 ) while a light-source section ( 11 ) and other elated sections are gradually moved by a moving section ( 15 ). Every time a set of data for one measurement position is acquired, a measurement monitoring image creator ( 4 ) creates a thumbnail age by reducing the size of a hologram image which is based on original data (two-dimensional distribution of light intensity). A display processor ( 25 ) pastes the create thumbnail image to progressively complete the hologram image of the entire plate to be displayed on a display unit ( 27 ). A measurement operator watches the hologram image during the execution of the measurement. When it has been concluded that the ongoing measurement is inappropriate, the operator presses a measurement stop button to immediately discontinue the measurement. Thus, When there is a problem with the measurement, such as a foreign object mixed in the sample, the measurement can be discontinued before a phase image or intensity image based on the hologram data is reconstructed on the server after the completion of the entire measurement, so as to avoid wasting time for the useless measurement.

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08-04-2021 дата публикации

Hybrid 3D Inspection System

Номер: US20210102892A1
Принадлежит:

An optical inspection apparatus includes an interferometer module, which is configured to direct a beam of coherent light toward an area under inspection and to produce a first image of interference fringes of the area. The apparatus also includes a triangulation module configured to project a pattern of structured light onto the area, and at least one image sensor configured to capture the first image of interference fringes and a second image of the pattern that is reflected from the area. Beam combiner optics are configured to direct the beam of coherent light and the projected pattern to impinge on the same location on the area. A processor is configured to process the first and second images in order to generate a 3D map of the area. 1. An optical inspection apparatus , comprising:an interferometer module, which is configured to direct a beam of coherent light toward an area under inspection, to receive the beam reflected from the area, and to produce a first image of interference fringes produced by combining the reflected beam with a reference beam;a triangulation module, comprising a projector configured to project a pattern of structured light onto the area under inspection;at least one image sensor configured to capture the first image of the interference fringes and a second image of the pattern that is reflected from the area under inspection;beam combiner optics, which are configured to direct the beam of coherent light along a first optical axis to impinge on a location on the area under inspection at a first angle of incidence, and to direct the projected pattern to impinge on the location along a second optical axis, at a second angle of incidence that is different from the first angle of incidence; anda processor configured to process the first and second images in order to extract respective first and second three-dimensional (3D) measurements of the area under inspection, and to combine the first and second 3D measurements in order to generate a ...

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04-04-2019 дата публикации

Method for observing a sample, by calculation of a complex image

Номер: US20190101484A1

The invention relates to a method for observing a sample ( 15 ), comprising the illumination of the sample using a light source ( 11 ) and the acquisition of an image (Io) of the sample using an image sensor ( 16 ), the sample being disposed between the image sensor and the light source. Iterative steps are applied to the acquired image (Io), also referred to as a hologram, comprising: a single iterative numerical propagation (h), such as to estimate a complex image (A) of the sample in a reconstruction plane (P 10 ) or in a detection plane (P 0 ), in which the image sensor extends. The complex image can be used for the characterisation of the sample.

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02-06-2022 дата публикации

Imaging system for imaging in a controlled environment

Номер: US20220171332A1
Автор: Etienne Cuche, Yves Emery
Принадлежит: Lyncee Tec SA

The present disclosure concerns an imaging system for imaging a sample immersed in a controlled environment. The system comprises—at least one enclosure configured to hold at least one imaging sensor or camera inside the enclosure, the enclosure including at least one opening and at least one transparent window for imaging the sample; and—a flexible channel comprising a first extremity and a second extremity, the first extremity being connected to the enclosure at said at least one opening and the second extremity being configured to be connected to a wall of the hermetic chamber, the flexible channel defining or enclosing a passage extending through the flexible channel and to or into the enclosure.

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19-04-2018 дата публикации

DIGITAL HOLOGRAPHIC IMAGING APPARATUS AND ILLUMINATION APPARATUS

Номер: US20180107158A1
Автор: WATANABE Satoshi
Принадлежит: OLYMPUS CORPORATION

Provided is a digital holographic imaging apparatus, comprising: an illumination portion () having an illumination light emission surface () for emitting coherent light of a specific wavelength as illumination light toward an object () side relative to the illumination light emission surface (), and a reference light emission surface () for emitting the coherent light, as reference light, in a direction opposite to the illumination light; and an image sensor () located on the reference light emission surface () side of the illumination portion () and imaging an interference pattern between object light having been modulated by the object () and passed through the illumination portion () and the reference light of the illumination light, the image sensor () having a pixel array () comprising two-dimensionally aligned pixels. 1. A digital holographic imaging apparatus , comprising:an illumination portion comprising: an illumination light emission surface for emitting, as illumination light, coherent light of a specific wavelength toward an object side; and a reference light emission surface located on the opposite side to the object side relative to the illumination light emission surface, the reference light emission surface emitting, as reference light, the coherent light in a direction opposite to the illumination light; andan image sensor located on the reference light emission surface side of the illumination portion, the mage sensor imaging an interference pattern between object light and the reference light, the object light being part of the illumination light having been modulated by the object and passed through the illumination portion, the image sensor having a pixel array including two-dimensionally arranged pixels,wherein: a light source portion that emits the coherent light; and', 'a plane optical waveguide portion that propagates the coherent light from the light source portion,, 'the illumination portion includes 'a plane optical waveguide having a ...

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19-04-2018 дата публикации

Method for phase retrieval to reduce a sampling requirement when imaging a dynamic process

Номер: US20180107160A1
Принадлежит: UChicago Argonne LLC

A method for retrieving phase information in a coherent diffraction imaging process includes acquiring a plurality of 3D data sets, each 3D data set corresponding to one of a plurality of time states, and reconstructing a 3D image of the object at a given time state using the 3D data set from all of the time states. Each 3D data set is acquired by: illuminating an object positioned in a first position with a coherent beam; measuring a first 2D diffraction pattern using an area detector; rotating the object around a tilt axis thereof to a second position that is different from the first position; re-illuminating the object positioned in the second position with the coherent beam; re-measuring a second 2D diffraction pattern using the area detector; and repeating the rotating, re-illuminating and re-measuring steps such that each 3D data set includes a predetermined number of diffraction patterns.

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20-04-2017 дата публикации

Systems and Methods for Performing Self-Interference Incoherent Digital Holography

Номер: US20170108829A1
Автор: Kim Myung K.
Принадлежит: UNIVERSITY OF SOUTH FLORIDA

In one embodiment, a self-interference incoherent digital holography system including a light sensor and a diffractive filter configured to receive light from an object to be holographically imaged and generate holographic interference patterns on the light sensor. A self-interference incoherent digital holography system comprising: a light sensor; and a diffractive filter configured to receive light from an object to be holographically imaged and generate holographic interference patterns on the sensor. 1. A self-interference incoherent digital holography system comprising:a light sensor; anda diffractive filter configured to receive light from an object to be holographically imaged and generate holographic interference patterns on the sensor.2. The system of claim 1 , wherein the light sensor is a charge-coupled device.3. The system of claim 1 , wherein the diffractive filter comprises two superposed Fresnel mask patterns.4. The system of claim 3 , wherein the Fresnel mask patterns have different focal lengths.5. The system of claim 4 , wherein the Fresnel mask patterns are angularly offset relative to each other.6. The system of claim 1 , wherein the system is implemented in a microscope.7. The system of claim 1 , wherein the system is implemented in a telescope.8. The system of claim 1 , wherein the system is implemented in a holographic camera.9. A method for creating a holographic image of an object claim 1 , the method comprising:receiving incoherent light from the object with a diffractive filter comprising superposed Fresnel mask patterns; andgenerating holographic interference pattern on a light sensor using the diffractive filter.10. The method of claim 9 , wherein receiving incoherent light comprises receiving x-ray light.11. The method of claim 9 , wherein receiving incoherent light comprises receiving ambient light.12. The method of claim 9 , wherein the superposed Fresnel mask patterns have different focal lengths.13. The method of claim 9 , wherein ...

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02-04-2020 дата публикации

Method and system for observing a sample under ambient lighting

Номер: US20200103337A1
Автор: Thomas Bordy

A method for observing a sample is placed between a light source and an image sensor, comprising at least 10000 pixels, the light source emits an illuminating beam, which propagates to the sample, the light beam is emitted in an illumination spectral band (Δλ 11 ) lying above 800 nm, the method comprising the following steps: (a) illuminating the sample with the light source; (b) acquiring an image of the sample (I 0 ) with the image sensor, no image-forming optics being placed between the sample and the image sensor; and (c) the image sensor being configured such that it has a detection spectral band (Δλ 20 ), which blocks wavelengths in the visible spectral band, such that the image may be acquired in ambient light.

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10-07-2014 дата публикации

APPARATUS AND METHOD FOR DISPLAYING HOLOGRAM IMAGE

Номер: US20140192146A1

Provided is an apparatus and method for displaying a hologram image that may display a hologram image created by tracking a position of a pupil of a user using an acquired user image, tracking a position of a light source of a reflection hologram image that is reflected from appearance of the user, and by correcting a position of a light source of a display hologram image based on the position of the pupil of the user. 1. An apparatus for displaying a hologram image , the apparatus comprising:an image acquiring unit to acquire a user image;an image analyzer to track a position of a pupil of a user using the user image, and to track a position of a light source of a reflection hologram image that is reflected from appearance of the user;a hologram creator to create a display hologram image corresponding to the position of the pupil of the user;a light source provider to control a position of a light source of the display hologram image based on the position of the pupil of the user; anda hologram display unit to display the display hologram image.2. The apparatus of claim 1 , wherein the image acquiring unit comprises:a user image camera to acquire a pupil image of the user; andan infrared (IR) image camera to acquire the reflection hologram image that is created by an IR light that is diffracted from the hologram display unit and thereby reflected.3. The apparatus of claim 2 , wherein the user image camera comprises:a three-dimensional (3D) position tracking camera to track a 3D position of the pupil of the user in 3D space.4. The apparatus of claim 1 , wherein the image analyzer calculates a mismatching level between a position of a viewing window and the position of the pupil of the user based on the reflection hologram image.5. The apparatus of claim 4 , wherein the light source provider controls the position of the light source to match a position of the viewing window.6. The apparatus of claim 1 , wherein the image analyzer analyzes a center position error ...

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02-04-2020 дата публикации

HOLOGRAPHY RECONSTRUCTION METHOD AND PROGRAM

Номер: US20200105498A1
Принадлежит:

A lensless Fourier transform holography high accuracy reconstruction method using a charged particle beam apparatus which holds a sample on a diffraction surface of a diffraction grating provided on the downstream side of a traveling direction of the charged particle beam and which is formed of a material having permeability. The charged particle beam passed through the diffraction surface is image-formed, and the formed image is detected. An opening region of the diffraction grating is smaller than an irradiation region of the charged particle beam on the diffraction grating. Image data is obtained in a state where the irradiation region of the charged particle beam diffracted with the diffraction grating is within the irradiation region of the charged particle beam transmitted through the diffraction grating. Plural holograms obtained based on the image data are Fourier transformed and an intensity distribution image is displayed and stored. 1. A holography reconstruction method with a charged particle beam apparatus , wherein the charged particle beam apparatus includes an irradiation optical system that irradiates a charged particle beam; a diffraction grating , provided on the downstream side of a traveling direction of the irradiated charged particle beam , that is formed of a material having permeability with respect to the charged particle beam; a sample holder that is capable of holding a sample on a diffraction surface of the diffraction grating; an image formation optical system that image-forms the charged particle beam passed through the diffraction surface; an image detector that detects image formation with the image formation optical system; and a controller that processes image data detected with the image detector ,wherein the method comprises:making an opening region of the diffraction grating smaller than an irradiation region of the charged particle beam to the diffraction grating, with the irradiation region of the charged particle beam ...

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27-04-2017 дата публикации

Method and Device for Drug Screening

Номер: US20170115201A1
Принадлежит: IMEC VZW

The present disclosure relates to devices and methods configured to perform drug screening on cells. At least one embodiment relates to a lens-free device for performing drug screening on cells. The lens-free device includes a substrate having a surface. The lens-free device also includes a light source positioned to illuminate the cells, when present, on the substrate surface with a light wave. The lens-free device further includes a sensor positioned to detect an optical signal caused by illuminating the cells. The substrate surface includes a microelectrode array for sensing an electrophysiological signal from the cells. 1. A lens-free device for performing drug screening on cells , comprising:a substrate having a surface;a light source positioned to illuminate the cells, when present, on the substrate surface with a light wave; anda sensor positioned to detect an optical signal caused by illuminating the cells,wherein the substrate surface comprises a microelectrode array for sensing an electrophysiological signal from the cells.2. The lens-free device according to claim 1 , wherein the substrate surface is a reflective surface for reflecting the light wave claim 1 , and wherein the sensor is positioned to detect the reflected light wave.3. The lens-free device according to claim 2 , further comprising a beam-splitting device positioned in between the substrate and the sensor and configured to direct the light wave towards the cells and further configured to transmit the reflected light wave.4. The lens-free device according to claim 2 , wherein the sensor comprises a through-hole claim 2 , and wherein the light source is positioned to emit the light wave through the through-hole.5. The lens-free device according to claim 1 , wherein the substrate is transparent claim 1 , at least for the optical signal claim 1 , and wherein the sensor is positioned to detect the optical signal through the substrate.6. The lens-free device according to wherein the substrate ...

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18-04-2019 дата публикации

PORTABLE DIFFRACTION-BASED IMAGING AND DIAGNOSTIC SYSTEMS AND METHODS

Номер: US20190113451A1
Принадлежит:

The disclosure features systems and methods for measuring and diagnosing target constituents bound to labeling particles in a sample. The systems include a radiation source, a sample holder, a detector configured to obtain one or more diffraction patterns of the sample each including information corresponding to optical properties of sample constituents, and an electronic processor configured to, for each of the one or more diffraction patterns: (a) analyze the diffraction pattern to obtain amplitude information and phase information corresponding to the sample constituents; (b) identify one or more particle-bound target sample constituents based on at least one of the amplitude information and the phase information; and (c) determine an amount of at least one of the particle-bound target sample constituents in the sample based on at least one of the amplitude information and the phase information. 1. A diagnostic system for measuring target constituents bound to labeling particles in a sample , the system comprising:a radiation source configured to generate illumination radiation;a sample holder configured to support the sample so that the sample is exposed to the illumination radiation;a detector configured to obtain one or more diffraction patterns of the sample, wherein each of the diffraction patterns comprises information corresponding to optical properties of sample constituents; and (a) analyze the diffraction pattern to obtain amplitude information and phase information corresponding to the sample constituents;', '(b) identify one or more particle-bound target sample constituents based on at least one of the amplitude information and the phase information; and', '(c) determine an amount of at least one of the particle-bound target sample constituents in the sample based on at least one of the amplitude information and the phase information., 'an electronic processor configured to, for each of the one or more diffraction patterns2. The system of claim 1 , ...

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18-04-2019 дата публикации

SYSTEM, APPARATUS AND METHOD FOR EXTRACTING IMAGE CROSS-SECTIONS OF AN OBJECT FROM RECEIVED ELECTROMAGNETIC RADIATION

Номер: US20190113888A1
Автор: ROSEN Joseph
Принадлежит:

An apparatus and method to produce a hologram of a cross-section of an object includes an electromagnetic radiation assembly configured to receive a received electromagnetic radiation, such as light, from the object. The electromagnetic radiation assembly is further configured to diffract the received electromagnetic radiation and transmit a diffracted electromagnetic radiation. An image capture assembly is configured to capture an image of the diffracted electromagnetic radiation and produce the hologram of the cross-section of the object from the captured image. The hologram of the cross-section includes information regarding a single cross-section of the object. 1an electromagnetic radiation assembly different from the object, said electromagnetic radiation assembly configured to receive the emitted electromagnetic radiation from the object, diffract the received electromagnetic radiation, and transmit a diffracted electromagnetic radiation;an image capture assembly configured to capture at least one image of the diffracted electromagnetic radiation, and produce holograms of plural cross-sections of the object from the at least one captured image, each of the holograms including information regarding a single cross section of the object, anda varying device configured to vary a distance between the object and at least one component of the electromagnetic radiation assembly, whereinthe electromagnetic radiation assembly is between the object and the image capture assembly.. An apparatus configured to produce holograms of plural cross sections of an object that emits an emitted electromagnetic radiation, said apparatus comprising: This application is a continuation of U.S. application Ser. No. 15/475,657 filed Mar. 31, 2017, which is a continuation Ser. No. 14/331,720, filed Jul. 15, 2014 (now U.S. Pat. No. 9,645,548 issued May 9, 2017), which is a continuation of U.S. application Ser. No. 14/083,044, filed Nov. 18, 2013 (now abandoned), which is a continuation of ...

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09-04-2020 дата публикации

Method for determining parameters of a particle

Номер: US20200110017A1

A method for determining a parameter of a particle present in a sample, the method comprising the following steps: a) illuminating the sample with the light source, the light source emitting an incident light wave that propagates along a propagation axis; b) acquiring an image of the sample with the image sensor, the image sensor being exposed to an exposure light wave; c) determining a position of the particle in the detection plane; d) on the basis of the acquired image, applying a propagation operator, for a plurality of distances from a detection plane, so as to estimate, at each distance, a complex amplitude of the exposure light wave; e) on the basis of the complex amplitude estimated, at various distances, obtaining a profile representing a variation of the complex amplitude of the exposure light wave along an axis parallel to the propagation axis and passing through the position of the particle. The particle may associated with a set of parameters, comprising at least a size of the particle and a refractive index of the particle.

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13-05-2021 дата публикации

DIGITAL HOLOGRAPHIC MICROSCOPY FOR DETERMINING A VIRAL INFECTION STATUS

Номер: US20210142472A1
Принадлежит:

A method for providing a viral infection status of at least one cell in a cell sample comprising receiving holographic information () of the cell sample obtained by digital holographic microscopy, and determining from the holographic information, the viral infection status () of the at least one cell. 1. A method for providing a viral infection status of at least one cell in a cell sample comprising receiving holographic information of the cell sample obtained by digital holographic microscopy , and determining from the holographic information , the viral infection status of the at least one cell , wherein the infection status is determined from cellular parameter data comprising one or more measured cellular parameters of the cell derived from the holographic information wherein the one or more measured cellular parameters , MCPs , comprises a subset of the MCPs of Table 1 , where the subset comprises one or more MCP from at least one of the groups (a) Phase Texture (F40 to F51) , (b) Refraction Peak (F20 , F33-F37) , (c) Morphology (F2-F19 , F70-72).2. The method according to claim 1 , wherein subset comprises one or more (group (a)) MCPs selected from F45 (ID PhaseCorrelationFeature) claim 1 , F44 (ID PhaseContrastFeature) claim 1 , F48 (ID PhaseSkewnessFeature) claim 1 , F47 (ID PhaseHomogeneityFeature) claim 1 , F43 (ID PhaseAverageUniformityFeature) claim 1 , F51 (ID PhaseUniformityFeature).3. The method according to claim 1 , wherein subset comprises one or more (group (b)) MCPs selected from F20 (ID EquivalentPeakDiameterFeature) claim 1 , F33 (ID PeakAreaFeature) claim 1 , F34 (ID PeakAreallormalizedFeature) claim 1 , F36 (ID PeakHeightFeature) claim 1 , F37 (ID PeakHeightNormalizedFeature).4. The method according claim 1 , wherein subset comprises one or more (group (c)) MCPs selected from F8 (ID EquivalentCellDiameterFeature) claim 1 , F17 (ID RadiusMeanFeature) claim 1 , F8 (ID Equivalent Diameter) claim 1 , F3 (ID CellAreaFeature) claim 1 , F18 (ID ...

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27-05-2021 дата публикации

Optical Imaging with Unshifted Reference Beam

Номер: US20210153743A1
Принадлежит:

An ultrasound emitter launches an ultrasonic signal into a diffuse medium such as tissue. The diffuse medium is illuminated with an infrared illumination signal. activating an ultrasound emitter to launch an ultrasonic signal into a diffuse medium. An infrared reference beam is interfered with an infrared exit signal having an infrared wavelength that is the same as the infrared illumination signal. An infrared image is captured of the interference of the infrared reference beam with the infrared exit signal. 1. A method of medical imaging comprising:illuminating tissue with an infrared illumination signal having an infrared wavelength;interfering an infrared reference beam with an infrared exit signal, wherein the infrared exit signal is the infrared illumination signal exiting the tissue, and wherein the infrared reference beam has the infrared wavelength that is the same as the infrared illumination signal;capturing a base holographic infrared image of an interference of the infrared reference beam with a base infrared exit signal;scanning an ultrasound emitter to direct an ultrasonic signal to a plurality of voxels of the tissue while the infrared illumination signal is illuminating the tissue, wherein the base holographic infrared image is captured when the ultrasonic signal is not propagating through the tissue; andcapturing a plurality of holographic infrared images corresponding to the plurality of voxels that the ultrasound emitter is scanned to, the plurality of holographic images capturing an interference of the infrared reference beam with the infrared exit signal at a time when the ultrasonic signal is directed to a particular voxel in the plurality of voxels.2. The method of further comprising:generating a composite image of the tissue based on differences between the plurality of holographic infrared images and the base holographic infrared image.3. The method of claim 2 , wherein generating the composite image includes:generating first intensity data ...

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25-04-2019 дата публикации

DEVICE AND METHOD FOR OBSERVING AN OBJECT BY LENSLESS IMAGING

Номер: US20190120747A1
Принадлежит:

A device and a method for observing an object by imaging, or by lensless imaging. The object is retained by a holder defining an object plane inserted between a light source and an image sensor, with no enlargement optics being placed between the object and the image sensor. An optical system is arranged between the light source and the holder and is configured to form a convergent incident wave from a light wave emitted by the light source, and for forming a secondary light source, conjugated with the light source, positioned in a half-space defined by the object plane and including the image sensor, such that the secondary source is closer to the image sensor than to the holder. This results in an image with a transversal enlargement factor having an absolute value of less than 1. 116-. (canceled)17. A device for observing an object , comprising:a light source, configured to generate an emission light wave, that propagates along a propagation axis;an image sensor;a holder configured to hold an object, the holder being placed between the image sensor and the light source such that the image sensor is configured to form an image of the object held on the holder;an optical system, placed between the light source and the holder, the optical system configured to form, from the emission light wave, a convergent incident light wave that propagates from the optical system to the holder;wherein:the holder defines an object plane, that is perpendicular to the propagation axis and that passes through the holder, the optical system being configured to conjugate the light source with a secondary source that is located in a half space defined by the object plane and that includes the image sensor;the optical system is configured such that the secondary source is located closer to the image sensor than to the holder, such that the image of the object, held on the holder, on the image sensor is affected by a magnification lower than 1.18. The device of claim 17 , wherein the ...

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16-04-2020 дата публикации

Method and Device for Label-Free, High Throughput Holographic Screening and Enumeration of Tumor Cells in Blood

Номер: US20200116617A1
Принадлежит:

The present invention includes method and device for label-free holographic screening and enumeration of tumor cells in blood for use in connection with cancer treatments and monitoring. 1. A digital holographic microscope to enumerate cells in bulk flow comprising:a laser source for providing a laser beam;a micro-objective, a pinhole device and a collimating lens in optical communication with the collimated laser beam;a mirror in optical communication with the collimated laser beam;a sample chamber in optical communication with the mirror, wherein the sample chamber comprises a sample flow inlet on a first side of the sample chamber connected to a sample flow outlet on a second side of the sample chamber by a microchannel, wherein a sample comprising numerous cells is transported at a bulk flow rate through the microchannel from the sample flow inlet to the sample flow outlet;a detector in optical communication with the microchannel, wherein the collimated laser beam passes through microchannel and interacts with the numerous cells to generate a respective hologram at the detector;wherein the detector obtains a numerical reconstruction from the respective hologram; andwherein the detector obtains a focused image of the numerous cells using the numerical reconstruction.2. The device of claim 1 , wherein the numerous cells are enumerated by looking at a size claim 1 , a maximum intensity and a mean intensity of the focused image.3. The device of claim 1 , wherein the sample chamber comprises more than two parallel paths to accommodate more than two parallel samples.4. The device of claim 1 , further comprising a loading stage having more than two parallel sample paths in parallel communication with more than two parallel paths in parallel communication with more than two parallel microchannels to accommodate more than two parallel samples.5. The device of claim 1 , wherein the detector or a processor finger-prints the numerous cells based on wherein the numerous ...

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25-04-2019 дата публикации

DIGITAL HOLOGRAPHIC IMAGING APPARATUS

Номер: US20190121290A1
Автор: Okamura Toshiro
Принадлежит: OLYMPUS CORPORATION

An illumination unit emits illumination light to a specimen held by a sample holder, which includes an AF mark that changes at least the amplitude or phase of part of the illumination light. An image sensor includes multiple pixels two-dimensionally arranged on an imaging surface, captures an image of the intensity distribution of an interference pattern formed on the imaging surface, and outputs captured image data. An AF operation unit generates a first intensity distribution representing a measurement value of the interference pattern corresponding to the AF mark based on the captured image data, generates a second intensity distribution representing a calculation value of an interference pattern corresponding to the AF mark by calculation, and executes an autofocus operation wherein the first intensity distribution approaches the second. A reconstruction calculation unit reconstructs a subject image representing the specimen based on the captured image data. 1. A digital holographic imaging apparatus comprising:an illumination unit structured to emit an illumination light to a specimen;a sample holder structured to hold the specimen, and to have an AF mark structured to change at least one from among an amplitude and a phase of a part of the illumination light;an image sensor including a plurality of pixels arranged in a two-dimensional manner on an imaging surface, and structured to capture an image of an intensity distribution of an interference pattern formed on the imaging surface, and to output captured image data; andone or more processor being configured to:generate a first intensity distribution based on the captured image data, the first intensity distribution representing a measurement value of an interference pattern that corresponds to the AF mark;calculate a second intensity distribution, the second intensity distribution representing a calculated value of the interference pattern that corresponds to the AF mark;execute an autofocus operation such ...

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25-04-2019 дата публикации

DIGITAL HOLOGRAPHIC RECONSTRUCTION DEVICE AND METHOD USING SINGLE GENERATION PHASE SHIFTING METHOD

Номер: US20190121292A1
Принадлежит: NAEILHAE, CO. LTD.

A time delay error occurring in the case of acquiring two holograms (object hologram and reference hologram) necessary for reconstruction in the related art or in the case of acquiring four physical holograms having different phase shift degrees may be removed. DC noise (including background noise) may be completely removed by using a software-implemented phase shifting method. 1. A digital holographic reconstruction device using a single generation phase shifting method , the digital holographic reconstruction device comprising:a light source unit emitting a single-wavelength light;a collimator collimating the single-wavelength light emitted from the light source unit;a light splitter splitting the single-wavelength light passed through the collimator into an object beam and a reference beam;an object beam objective lens transmitting the object beam generated by the light splitter;a reference beam objective lens transmitting the reference beam generated by the light splitter;an optical mirror reflecting the reference beam passed through the reference beam objective lens;a recording medium recording an interference pattern formed when an object beam passed through the object beam objective lens and then reflected from a surface of a measurement target object and a reference beam reflected by the optical mirror pass through the object beam objective lens and the reference beam objective lens respectively and then are transmitted to the light splitter; anda processor receiving and storing an image file generated by converting the interference pattern from the recording medium,wherein the processor generates first to fourth phase-shifted object holograms from an object hologram acquired from the image file by using a wave optics-based interference equation, generates a complex conjugate hologram by removing direct current (DC) noise and virtual image information by using the generated first to fourth phase-shifted object holograms and a software-implemented phase ...

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12-05-2016 дата публикации

COMMON-MODE DIGITAL HOLOGRAPHIC MICROSCOPE

Номер: US20160131882A1
Принадлежит:

A digital holographic microscope including a single mode fiber collimated light source which provides illumination for both the ‘science’ and ‘reference’ arms, a pair of microscope objectives located side-by side, and illuminated by the common beam, a relay lens whose center is between the two objectives, and a focal plane element where the interference pattern is measured. A lens-less digital holographic microscope and a reflective digital holographic microscope are also disclosed. 1. An imaging system , comprising:at least one coherent electromagnetic radiation source emitting electromagnetic radiation;a collimator positioned to collimate the electromagnetic radiation, to form collimated electromagnetic radiation; a sample mounted on the sample mount interacts with the collimated electromagnetic radiation to form sample electromagnetic radiation, and', 'one or more references mounted on the sample mount interact with the collimated electromagnetic radiation to form reference electromagnetic radiation; and, 'a sample mount positioned such that at least a portion of the sample electromagnetic radiation is transmitted through the first lens, and then the relay lens, to a detector,', 'at least a portion of the reference electromagnetic radiation is transmitted through the second lens, and then the relay lens, to the detector,', 'the portion of the sample electromagnetic radiation and the portion of the reference electromagnetic radiation are directed by the relay lens onto the detector at an angle with respect to each other so as to form an interference pattern on the detector, and', 'one or more computers can compute an image of the sample from the interference pattern detected by the detector., 'a microscope lens assembly, comprising a first lens, a second lens, and a relay lens, positioned such that2. The system of claim 1 , wherein the system is an off-axis digital holographic microscope.3. The system of claim 1 , wherein the electromagnetic radiation comprises a ...

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31-07-2014 дата публикации

FAST PROCESSING OF INFORMATION REPRESENTED IN DIGITAL HOLOGRAMS

Номер: US20140210942A1
Автор: Tsang Peter Wai Ming
Принадлежит: CITY UNIVERSITY OF HONG KONG

Techniques for fast processing of information represented in digital holograms to facilitate generating and displaying 3-D holographic images representative of a 3-D object scene are presented. A holographic generator component (HGC) can receive or generate information representing a 3-D object scene. In real or near real time, the HGC can back-project a hologram to a virtual 2-D image known as a virtual diffraction plane (VDP); process the VDP to enhance optical properties of the VDP to facilitate enhancing or adjusting the optical properties of the 3-D holographic images when displayed by a display component; and expand the VDP to facilitate generating 3-D holographic images that can represent or recreate the 3-D object scene. The HGC can thereby process digital 3-D holograms of moderate size and display 3-D holographic images generated from the processed 3-D holograms at a desirably fast video rate. 1. A system , comprising:at least one memory that stores computer executable components; and a hologram enhancer component that projects a hologram on a virtual diffraction plane that is within a defined distance of an object space associated with an object scene represented by the hologram, processes one or more optical properties of one or more respective regions on the virtual diffraction plane to facilitate modification of the one or more optical characteristics of the one or more respective regions on the virtual diffraction plane to generate a processed virtual diffraction plane that facilitates generation of a processed hologram that represents the object scene; and', 'a display component that presents one or more holographic images associated with the processed hologram., 'at least one processor that facilitates execution of the computer executable components stored in the at least one memory, the computer executable components, comprising2. The system of claim 1 , wherein the hologram enhancer component expands the processed virtual diffraction plane to ...

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10-05-2018 дата публикации

SYSTEM AND METHOD FOR THE REMOVAL OF TWIN-IMAGE ARTIFACT IN LENS FREE IMAGING

Номер: US20180128590A1
Принадлежит:

The present disclosure provides a system for lens-free imaging that includes a processor in communication with a lens-free imaging sensor. The processor is programmed to operate the imaging sensor to obtain a holographic image and to extract, from the holographic image, a plurality of patches, wherein the plurality of patches is a set of all fixed-size patches of the holographic image. The processor is also programmed to generate a dictionary D comprising a plurality of atoms, wherein the dictionary is generated by solving 2. The system of claim 1 , further comprising an image sensor.3. The system of claim 2 , wherein the image sensor is an active pixel sensor claim 2 , a CCD claim 2 , or a CMOS active pixel sensor.5. The method of claim 4 , wherein the plurality of patches is the set of all possible patches of the holographic image.6. The method of claim 4 , further comprising sorting the atoms of the dictionary into a cell atoms and background atoms.7. The method of claim 6 , wherein sorting comprises thresholding the lnorm of each atom of the dictionary.8. The method of claim 6 , wherein the holographic image is an image of whole blood.9. The method of claim 8 , wherein each cell atom of the dictionary is a red blood cell claim 8 , a white blood cell claim 8 , or a platelet.10. The method of claim 4 , wherein the dictionary is generated from more than one holographic image.11. The method of claim 4 , further comprising normalizing each patch of the plurality of patches to have zero mean and unit Euclidean norm.12. The method of claim 6 , further comprising:obtaining a sample holographic image;extracting, from the sample holographic image, a plurality of sample image patches, wherein the set of sample image patches comprises all non-overlapping patches in the sample holographic image; andencoding each patch of the plurality of sample image patches using the foreground dictionary; andgenerating a reconstructed image of the sample image using the encoded patches.14. ...

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10-05-2018 дата публикации

Apparatus for manufacturing holographic optical element, and apparatus for reconstructing holograms

Номер: US20180129165A1

An apparatus for manufacturing a hologram includes a holographic optical element on which a first interference pattern of a first signal beam and a first reference beam is recorded and a second interference pattern of a second signal beam modulated by a Fourier lens and a second reference beam is recorded. Also, an apparatus for reconstructing a hologram by using the holographic optical element is provided.

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11-05-2017 дата публикации

DIGITAL HOLOGRAPHIC METHOD OF MEASURING CELLULAR ACTIVITY AND MEASURING APPARATUS WITH IMPROVED STABILITY

Номер: US20170131682A1
Автор: Nolte David D.
Принадлежит:

Motility contrast imaging (MCI) is a depth-resolved holographic technique to extract cellular and subcellular motion inside tissue. The holographic basis of the measurement technique makes it highly susceptible to mechanical motion. The motility contrast application, in particular, preferably includes increased mechanical stability because the signal is based on time-varying changes caused by cellular motion, which should not be confused with mechanical motion of the system. Apparatus for motility contrast imaging that provides increased mechanical stability are disclosed. It is based on common-path configurations, in which the signal and reference beams share optical elements in their paths to the detector. The two beams share mechanical motions in common, and hence those motions do not contribute to the signal. 1. A motility contrast imaging apparatus for imaging a tissue sample at a sample plane , the imaging apparatus comprising:an illumination source providing an illumination beam;a reference object defines the sample plane;wherein a first portion of the illumination beam is incident on the reference object, scattering of the first portion of the illumination beam by the reference object forming a reference beam; and a second portion of the illumination beam is incident on the tissue sample, scattering of the second portion of the illumination beam by the tissue sample forming a signal beam;a collecting element positioned to collect the reference beam after it has been scattered by the reference object and to collect the signal beam after it has been scattered by the tissue sample; anda detector positioned to detect the collected reference beam and the collected signal beam.2. The motility contrast imaging apparatus of further comprising a beam expander positioned to expand the illumination beam before the illumination beam is incident on the reference object and the tissue sample.3. The motility contrast imaging apparatus of wherein the beam expander is a ...

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11-05-2017 дата публикации

Analyzing Digital Holographic Microscopy Data for Hematology Applications

Номер: US20170132450A1
Принадлежит:

A method for analyzing digital holographic microscopy (DHM) data for hematology applications includes receiving a plurality of DHM images acquired using a digital holographic microscopy system. One or more connected components are identified in each of the plurality of DHM images and one or more training white blood cell images are generated from the one or more connected components. A classifier is trained to identify a plurality of white blood cell types using the one or more training white blood cell images. The classifier may be applied to a new white blood cell image to determine a plurality of probability values, each respective probability value corresponding to one of the plurality of white blood cell types. The new white blood cell image and the plurality of probability values may then be presented in a graphical user interface. 1. A method for analyzing digital holographic microscopy (DHM) data for hematology applications , the method comprising:receiving a plurality of DHM images acquired using a digital holographic microscopy system;identifying one or more connected components in each of the plurality of DHM images;generating one or more training white blood cell images from the one or more connected components;training a classifier to identify a plurality of white blood cell types using the one or more training white blood cell images;extracting a new white blood cell image from a new DHM image;applying the classifier to the new white blood cell image to determine a plurality of probability values, each respective probability value corresponding to one of the plurality of white blood cell types; andpresenting the new white blood cell image and the plurality of probability values in a graphical user interface.2. The method of claim 1 , further comprising:prior to identifying the one or more connected components, applying a thresholding to the each of the plurality of DHM images to highlight bright spots in each respective DHM image.3. The method of claim ...

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01-09-2022 дата публикации

Digital Holography Microscope (DHM), and Inspection Method and Semiconductor Manufacturing Method Using the DHM

Номер: US20220276607A1
Принадлежит:

A low-cost digital holography microscope (DHM) that is capable of performing inspection at high speed while accurately inspecting an inspection object at high resolution, an inspection method using the DHM, and a method of manufacturing a semiconductor device by using the DHM are provided. The DHM includes: a light source configured to generate and output light; a beam splitter configured to cause the light to be incident on an inspection object and output reflected light from the inspection object; and a detector configured to detect the reflected light, wherein, when the reflected light includes interference light, the detector generates a hologram of the interference light, and wherein no lens is present in a path from the light source to the detector. 116-. (canceled)17. An inspection method using a digital holography microscope (DHM) comprising a light source and a detector , the inspection method comprising:generating light and making the light incident on an inspection object;detecting reflected light from the inspection object;analyzing the reflected light to determine whether a defect is present in the inspection object; andgenerating a hologram and analyzing the hologram when the reflected light comprises interference light,wherein the DHM has a lens-free path from the light source to the detector.18. The inspection method of claim 17 , wherein light diffracted and reflected at a portion of the inspection object where a defect is present and light reflected at a portion of the inspection object where no defect is present overlap each other claim 17 , thus generating interference fight when a defect is present in the inspection object.19. The inspection object of claim 17 , wherein making the light incident on the inspection object comprises:generating the light and making the light incident on a beam splitter, andmaking the light incident on the inspection object and outputting the reflected light from the inspection object by the beam splitter.20. The ...

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