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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Применить Всего найдено 4. Отображено 4.
23-05-2019 дата публикации

PREPARATION, RAW MATERIALS, PRODUCT, AND APPLICATION OF PHOTOCROSSLINKED HYDROGEL MATERIAL

Номер: WO2019095599A1
Автор: ZHU, Linyong, HUA, Yujie, LIN, Qiuning, ZHANG, Yiqing, BAO, Chunyan, ZHONG, Xuepeng
Принадлежит:

A photocrosslinked hydrogel material. The material is prepared by: dissolving a component A, a photosensitive polymer derivative, in a biocompatible medium to obtain a photosensitive polymer solution A; dissolving a component B, a photoinitiator, in the biocompatible medium to obtain a photoinitiator solution B; dissolving an auxiliary component C, another biocompatible polymer derivative, in the biocompatible medium to obtain a polymer solution C; and uniformly mixing the solution A and the solution B (or adding the solution C) to obtain a hydrogel precursor solution, and irradiating the hydrogel precursor solution with a light source, such that the hydrogel precursor solution is photocrosslinked to form a hydrogel. The hydrogel system features fast photocuring speed, strong tissue adhesion, excellent mechanical properties, good biocompatibility, and excellent clinical operation. The present invention further relates to a kit for the preparation of the hydrogel, as well as applications ...

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Номер записи: 1
14-07-2023 дата публикации

Biological 3D printing tissue engineering trachea as well as construction method and application thereof

Номер: CN116421359A
Автор: ZHOU GUANGDONG, HUO YINGYING, HUA YUJIE
Принадлежит:

The invention relates to a biological 3D printing tissue engineering trachea as well as a construction method and application thereof, namely a cartilage/vascularized fibrous tissue alternating tissue engineering trachea. The construction method comprises the following steps: firstly, wrapping cartilage cells with cartilage tissue specific hydrogel to prepare cartilage specific bio-ink; fiber tissue specific hydrogel is used for wrapping fibroblasts to prepare fiber specific bio-ink; then, through a double-needle extrusion type biological 3D printing technology, alternate printing is achieved, an annular tubular structure is formed, and a cartilage/fiber tissue alternate tubular structure is constructed through multi-layer stacking forming; further, vascularization of the fibrous tissue is achieved through a certain culture mode, and finally the relatively mature cartilage/vascularized fibrous tissue alternating tissue engineering trachea is obtained. The invention further provides application ...

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Номер записи: 2
23-05-2019 дата публикации

PREPARATION, RAW MATERIALS, PRODUCT, AND APPLICATION OF PHOTOCOUPLED SYNERGISTIC CROSSLINKED HYDROGEL MATERIAL

Номер: WO2019095600A1
Автор: ZHU, Linyong, HUA, Yujie, LIN, Qiuning, ZHANG, Yiqing, BAO, Chunyan, ZHONG, Xuepeng
Принадлежит:

Provided are preparation, raw materials, a product, and an application of a photocoupled synergistic crosslinked hydrogel material. The material is prepared by: dissolving a component A, a polymer derivative modified by an o-nitrobenzyl light trigger in a biocompatible medium to obtain a solution A, and dissolving a component B, an amino-containing polymer derivative or a double bond-containing polymer derivative or a fluorenyl-containing polymer derivative in the biocompatible medium to obtain a solution B; uniformly mixing the solution A, or adding the solution B thereto, to obtain a hydrogel precursor solution; irradiating the hydrogel precursor solution with a light source, such that the o-nitrobenzyl group in the component A simultaneously generates an aldehyde group/ketone group or a nitroso group under photoexcitation for double crosslinking, achieving a synergistic crosslinking effect. Further provided are a kit for the preparation of the hydrogel, as well as applications of the ...

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Номер записи: 3
11-04-2023 дата публикации

Allogeneic cartilage tissue compound based on immune isolation strategy as well as preparation method and application of allogeneic cartilage tissue compound

Номер: CN115944780A
Автор: HUO YINGYING, ZHOU GUANGDONG, HUA YUJIE
Принадлежит:

The invention belongs to the field of biomedical tissue engineering, and relates to an allogeneic cartilage tissue compound based on an immune isolation strategy as well as a preparation method and application of the allogeneic cartilage tissue compound. The semi-permeable membrane material with the immune isolation function is a polymer fiber membrane material prepared through an electrostatic spinning technology, and the polymer fiber membrane material can prevent immune cells or inflammatory cytokines from invading without hindering nutrient substance exchange. The preparation method comprises the following steps: culturing relatively mature regenerated cartilage tissue by a tissue engineering method, and wrapping the relatively mature regenerated cartilage tissue in a semi-permeable membrane material with an immune isolation effect to obtain the allogeneic cartilage tissue compound based on the immune isolation strategy. The allogeneic cartilage tissue compound can be used for regeneration ...

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Номер записи: 4