Nanometer fluorescent probe for specific gallbladder delivery as well as preparation method and application of nanometer fluorescent probe

The invention relates to the technical field of nano biological materials, in particular to a nano fluorescent probe for specific gallbladder delivery, a preparation method and application. The amphiphilic brush-shaped polymer nano fluorescent probe containing organic dye is prepared by synthesizing an organic dye monomer and carrying out block polymerization. The nano fluorescent probe prepared by the invention can be rapidly metabolized by the liver and stays in the gallbladder for a long time, and imaging and operation guidance of the gallbladder and the bile duct can be realized. Compared with clinically used indocyanine green (ICG), the prepared nano fluorescent probe for specific gallbladder delivery has the advantages that the preparation method is simple, the size regulation range is wide, the nano fluorescent probe has very good gallbladder enrichment characteristic and higher metabolic rate, has great clinical transformation potential, and is expected to replace ICG to become ...