27-06-2023 дата публикации
Номер: CN116327708A
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The invention discloses a preparation method of nano-particles and a preparation method of nano-drug-loaded particles, wherein the process is simple and controllable, and polyglutamic acid and tannic acid can be compounded into the nano-particles. The preparation method of the nano-particles for drug loading comprises the following steps: obtaining a first solution which comprises polyglutamic acid, tannic acid, water and N, N-dimethylformamide; obtaining a second solution, wherein the second solution comprises a carboxyl catalyst and water; and adding the second solution into the first solution, reacting for a period of time to generate a solid-liquid mixture, and carrying out solid-liquid separation treatment to obtain the nanoparticles. The preparation method of the nano drug-loaded particles comprises the following steps: adding the drug into the first solution or the second solution in the preparation method; in the generation process of the nano-particles, the drug is loaded on the ...
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