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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Применить Всего найдено 7. Отображено 7.
23-09-2015 дата публикации

NOVEL CATIONIC POLYPHOSPHAZENE COMPOUND, POLYPHOSPHAZENES-DRUG CONJUGATE COMPOUND AND PREPARING METHOD THEREOF

Номер: KR1020150107650A
Автор: SOHN, YOUN SOO, JUN, YONG JOO, AVAJI PRAKASH GOUDA
Принадлежит:

The present invention relates to a cationic linear polyphosphazene compound incorporating hydrophilic polyethylene glycol and one type selected from the group consisting of lysine, oligopeptide comprising lysine, aminoethanol, aminopropanol, aminobutanol, aminopentanol and aminohexanol as a spacer group; a polyphosphazenes-drug conjugate compound which is obtained by chemically bonding a hydrophobic drug to the compound; and a method for preparing the same, wherein the compound of the present invention is excellent in selectivity to cancer tissues and has very low toxicity, and thus is a new material with high possibility of commercialization as an anti-cancer drug. COPYRIGHT KIPO 2015 (AA) Taxotere (10 mg/kg) (BB) Example 12 (10 mg/kg) (CC) Example 12 (20 mg/kg) (DD) Example 12 (30 mg/kg) ...

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Номер записи: 1
09-11-2017 дата публикации

APPARATUS TO DETERMINE MIXING OF INCLUSION AND METHOD THEREOF

Номер: KR101795960B1
Автор: SON, YOEN SOO, KIM, JUNG SUB, JANG, GI MAN, JE, DO HYUP
Принадлежит: POSCO

According to one embodiment of the present invention, an apparatus to determine mixing of an inclusion comprises: a molten steel level detection unit detecting a molten steel level of a mold while molten steel is mixed from a tundish to the mold; a stopper position level detection unit detecting a position level of a stopper controlling an amount of supply of the molten steel supplied from the tundish to the mold; and a treatment unit determining a mixing timing and whether or not an inclusion is mixed from the tundish to the mold based on the position level of the stopper when the molten steel level exceeds a reference level. COPYRIGHT KIPO 2017 (731) Comparing unit (732) Analysis unit (733) Determination unit (740) Alarm warning unit (AA) NULL ...

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Номер записи: 2
30-11-2018 дата публикации

BREAKOUT DETECTION METHOD AND APPARATUS

Номер: KR101905832B1
Автор: KIM, HO GOOK, KIM, SUNG YONG, NA, JE HUN, SHIN, MIN CHUL, SON, YOEN SOO, LEE, HYO SEOK
Принадлежит: POSCO, AIN TECHNOLOGY CO., LTD.

The present invention relates to a breakout detection apparatus, which comprises: a photographing step of sequentially photographing a slab surface extracted from a mold; an image processing step of generating image processing information by detecting a change in brightness from sequentially photographed images photographed in the photographing step; and a breakout detection step of detecting breakout from the image processing information based on the entire area of a pixel area wherein the change in brightness exceeds a preset value. COPYRIGHT KIPO 2019 ...

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Номер записи: 3
17-09-2015 дата публикации

NOVEL CATIONIC POLYPHOSPHAZENE COMPOUND, POLYPHOSPHAZENES-DRUG CONJUGATE COMPOUND AND METHOD FOR PREPARING SAME

Номер: WO2015137777A1
Автор: SOHN, Youn Soo, JUN, Yong Joo, AVAJI, Prakash Gouda
Принадлежит:

The present invention relates to: a cationic linear polyphosphazene compound incorporating hydrophilic polyethylene glycol and lysine as a spacer group, oligopeptide comprising lysine, and one selected from the group consisting of aminoethanol, aminopropanol, aminobutanol, aminopentanol and aminohexanol; a polyphosphazenes-drug conjugate compound which is obtained by chemically bonding a hydrophobic drug to said compound; and a method for preparing the same, wherein the compound of the present invention is excellent in selectivity to cancer tissues and has very low toxicity, and thus is a new material with high possibility of commercialization as an anti-cancer drug.

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Номер записи: 4
05-11-2009 дата публикации

ARBORESCENT OLIGOPEPTIDE-CONTAINING CYCLOTRIPHOSPHAZENE, PREPARATION METHOD THEREOF AND DRUG DELIVERY SYSTEM CONTAINING THE SAME

Номер: WO2009134042A3
Автор: SOHN, Youn Soo, JUN, Yong Joo, CHOI, Sung Mo
Принадлежит:

The present invention provides a cyclotriphosphazene of Chemical formula 1 where an arborescent tetrapeptide is introduced to a cyclotriphosphazene together with a hydrophilic polyethyleneglycol, a preparation method thereof and a drug delivery system containing the same. The compound according to the present invention may form a strong hydrogel even at an extremely low concentration, for example, 2w/w% or lower. Moreover, the hydrogel produced from the compound of the present invention is useful as a drug delivery system for sustained release of drug, especially, a protein drug, since such a hydrogel has a biodegradability and a temperature sensitivity, can be prepared with ease, avoids inactivation of protein, and exhibits a sustained release property without a massive release of drugs.

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Номер записи: 5
28-06-2012 дата публикации

AMPHIPHILIC CYCLIC PHOSPHAZENE TRIMER, HYDROPHOBIC PHARMACEUTICAL FORMULATION MICELLIZED BY AMPHIPHILIC CYCLIC PHOSPHAZENE TRIMER, AND PREPARATION METHODS THEREOF

Номер: WO2012086964A3
Автор: SOHN, Youn-Soo, JUN, Yong-Joo
Принадлежит:

The present invention relates to an amphiphilic cyclic phosphazene trimer having biocompatibility and a preparation method thereof. In addition, the invention relates to a hydrophobic pharmaceutical formulation micellized by the amphiphilic cyclic phosphazene trimer and a preparation method thereof.

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Номер записи: 6
28-06-2012 дата публикации

AMPHIPHILIC CYCLIC PHOSPHAZENE TRIMER, HYDROPHOBIC PHARMACEUTICAL FORMULATION MICELLIZED BY AMPHIPHILIC CYCLIC PHOSPHAZENE TRIMER, AND PREPARATION METHODS THEREOF

Номер: WO2012086964A2
Автор: SOHN, Youn-Soo, JUN, Yong-Joo
Принадлежит:

The present invention relates to an amphiphilic cyclic phosphazene trimer having biocompatibility and a preparation method thereof. In addition, the invention relates to a hydrophobic pharmaceutical formulation micellized by the amphiphilic cyclic phosphazene trimer and a preparation method thereof.

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Номер записи: 7