20-11-1981 дата публикации
Номер: FR2482596A1
L'INVENTION A POUR OBJET LES COMPOSES DE FORMULE : (CF DESSIN DANS BOPI) DANS LAQUELLE X EN POSITION 5, 6, 7 OU 8, REPRESENTE UN ATOME D'HYDROGENE, UN ATOME D'HALOGENE, UN RADICAL ALCOYLE OU ALCOXY, UN RADICAL TRIFLUOROMETHYLE, UN RADICAL TRIFLUOROMETHYLTHIO OU UN RADICAL TRIFLUOROMETHOXY, R REPRESENTE UN ATOME D'HYDROGENE OU UN RADICAL ALCOYLE, R REPRESENTE UN RADICAL HETEROCYCLYIQUE, EVENTUELLEMENT SUBSTITUE, OU R REPRESENTE UN RADICAL PHENYLE, EVENTUELLEMENT SUBSTITUE, R REPRESENTE UN ATOME D'HYDROGENE, UN ATOME D'HALOGENE, UN RADICAL ALCOYLE, R REPRESENTE UN ATOME D'HYDROGENE OU UN ATOME D'HALOGENE ET R REPRESENTE UN ATOME D'HALOGENE, A LA CONDITION QUE R, R ET R NE REPRESENTENT PAS EN MEME TEMPS CHACUN UN ATOME DE FLUOR. LES COMPOSES DE FORMULE I PRESENTENT D'INTERESSANTES PROPRIETES PHARMACOLOGIQUES QUI JUSTIFIENT LEUR UTILISATION COMME MEDICAMENT. THE SUBJECT OF THE INVENTION IS TO COMPOUNDS OF FORMULA: (CF DRAWING IN BOPI) IN WHICH X IN POSITION 5, 6, 7 OR 8, REPRESENTS A HYDROGEN ATOM, A HALOGEN ATOM, A RADICAL ALCOHOL OR ALCOXY, A RADICAL TRIFLUOROMETHYL, A RADICAL TRIFLUOROMETHYLTHIO OR A RADICAL TRIFLUOROMETHOXY, R REPRESENTS AN ATOM OF HYDROGEN OR A RADICAL ALCOYL, R REPRESENTS A RADICAL HETEROCYCLYL, POSSIBLY AT A SUBSTANTIAL, SUBSEQUENTLY REPRESENT, REPRESENT, OR REPRESENT RADICAL REPRESENT A HALOGEN ATOM, A RADICAL ALCOYL, R REPRESENTS A HYDROGEN ATOM OR A HALOGEN ATOM AND R REPRESENTS A HALOGEN ATOM, PROVIDED THAT R, R AND R DO NOT REPRESENT AN ATOM AT THE SAME TIME. OF FLUOR. THE COMPOUNDS OF FORMULA I HAVE INTERESTING PHARMACOLOGICAL PROPERTIES WHICH JUSTIFY THEIR USE AS A MEDICINAL PRODUCT.
Подробнее
