ROTOR BLADE HAVING HEELS-OSCILLATING AND ROTOR OF GAS TURBINE ENGINE COMPRISING SUCH FINS.

HAUL-OFF YARN WITHIN THE STRAP OF THE UNDERWATER CATAPULT IN WHICH

COMBUSTION DEVICE LEAN FUEL INJECTION SYSTEM UPSTREAM OF THE NOZZLES

LIGHT TAG DEVICE, SYSTEM CONTAINER EQUIPPED WITH THE DEVICE AND METHOD OF MAKING SAME

Dispositif d'étiquette lumineuse, système de récipient équipé d'un tel dispositif et procédé de fabrication associé. L'invention concerne un dispositif d'étiquette lumineuse comprenant un support (1) réalisé majoritairement en un matériau conducteur de lumière, ledit support (1) comportant d'une part une face interne destinée à être apposée sur un récipient (3) et d'autre part une face externe (4) opposée, ledit dispositif comprenant une source lumineuse (5) agencée de manière à éclairer la tranche du support (1), et étant caractérisé en ce que le support (1) présente au moins une portion dont l'épaisseur est graduellement décroissante depuis une première section (7) de ladite portion jusqu'à une seconde section (8) opposée de ladite portion, et en ce que la source lumineuse (5) est agencée pour éclairer ladite première section (7) de façon à illuminer la face externe (4) par conduction de la lumière depuis la première section (7) vers la deuxième section (8). Dispositifs d'étiquettes lumineuses ...

FUEL REFORMEUR FOR DEVICE OF COMBUSTION OF ENGINE HAS GAS TURBINE AND PROCESS OF REFORMING

Reformeur (60) destiné à servir dans un moteur à turbine à gaz, comprenant un noyau (62) contenant une composition catalytique (65) et un canal d'entrée pour un mélange de combustibles, de l'air et de la vapeur. Un canal de sortie (66) transporte le courant de reformat, contenant des hydrocarbures reformés et ayant subi un craquage thermique et de grandes quantités d'hydrogène en vue d'une combinaison avec l'apport principal destiné au dispositif de combustion. La chaleur supplémentaire est transférée (et thermiquement intégrée) à l'aide d'un ou de plusieurs dispositifs d'échange de chaleur (72, 77) pour un premier et/ou un second courants auxiliaires de combustibles qui subissent un craquage thermique et une vaporisation avant de se combiner avec le reformat.

Supporting RMA API over active message

Procédés, appareils et logiciels pour mettre en œuvre des interfaces de programmation (API) de RMA par message actif (AM). Des demandes d'écriture AM et de lecture AM sont envoyées par un nœud local à un nœud distant pour écrire des données ou lire des données dans une mémoire sur le nœud distant en utilisant des techniques d'accès à la mémoire distante (RMA). Les demandes AM sont traitées par des gestionnaires AM correspondants qui effectuent automatiquement des opérations associées avec les demandes. Par exemple, pour les demandes d'écriture AM, un gestionnaire de demandes d'écriture AM peut écrire des données contenues dans une demande d'écriture AM dans un espace d'adresses distant situé dans la mémoire du nœud distant, ou générer une demande d'écriture RMA correspondante qui est mise dans une file d'attente RMA utilisée conformément à un système de messages marqués. Des opérations similaires sont effectuées par des gestionnaires de demandes de lecture AM. Les opérations de lecture ...

TURBOSHAFT ENGINE INCLUDING AN ELEMENT OF TUBE OF MIXTURE COMPRISING A VORTEX GENERATOR

Une turbomachine (2) comporte une section de compresseur (4), une chambre de combustion (8, 30, 47, 50) reliée fonctionnellement à la section de compresseur (4), un capot d'extrémité (10) monté sur la chambre de combustion (8, 30, 47, 50), et un ensemble de buses d'injection (20, 21, 22) reliées fonctionnellement à la chambre de combustion (8, 30, 47, 50). L'ensemble de buses d'injection (20, 21, 22) comporte une pluralité d'éléments de tube de mélange (100). Chaque élément de la pluralité d'éléments de tube de mélange (100) comporte une conduite (130) ayant une première entrée de fluide (132), une seconde entrée de fluide (134) agencée en aval de la première entrée de fluide (132), une extrémité d'évacuation (137) agencée en aval des première et seconde entrées de fluide (132, 134) et un générateur de tourbillons (144, 170, 184, 193, 194, 195, 220, 222) agencé entre les première et seconde entrées de fluide (132, 134). Le générateur de tourbillons (144, 170, 184, 193, 194, 195, 220, 222 ...

FUEL REFORMER FOR COMBUSTOR OF GAS TURBINE ENGINE AND METHOD OF REFORMING

TURBOMACHINE INCLUDING AN ELEMENT MIXING TUBE WITH VORTEX GENERATOR

LIGHT TAG DEVICE, SYSTEM CONTAINER EQUIPPED WITH THE DEVICE AND METHOD OF MAKING SAME

DEVICE OF COMBUSTION HAS SYSTEM Of LOW-GRADE FUEL INJECTION UPSTREAM OF the TUBES

Dispositif de combustion (100) pour brûler un flux de combustible et un flux d'air. Le dispositif de combustion (100) peut comprendre un certain nombre de buses (120) de combustible, un système d'injection (270) de combustible pauvre en amont des buses, placé en amont des buses (120) de combustible, et un volume annulaire de prémélange (250) placé entre les buses (120) de combustible et le système d'injection (270) de combustible pauvre en amont des buses, pour prémélanger le flux de combustible et le flux d'air.

COSMETIC COMPOSITION ANHYDROUS PIGMENTEE

ASSEMBLY TO COUPLE an ENGINE HAS GAS TURBINE HAS TURBO BLOWER ON UNESTRUCTURE Of PLANE

Generator comprises rotor structure having rotor frame supporting field turns and rectifier assembly, bus bar electrically connecting field turns to rectifier assembly, and grounding bushing electrically connecting bus bar to rotor frame

Un générateur (10) comprend une structure de rotor ayant un châssis de rotor qui supporte des enroulements de champ et un ensemble de redresseur. Le châssis de rotor comprend une ouverture (48) et une barre omnibus (42) passe à travers l'ouverture (48) et raccorde électriquement les enroulements de champ et l'ensemble de redresseur. Un manchon de mise à la terre (52) raccorde électriquement la barre omnibus au châssis de rotor.

Traction wire for underwater catapult, has set of connecting strands arranged at external abutment, where wire has sling traction function that allows only one mode of operation along entire length of barrel

Le fil tracteur à l'intérieur du sandow propulseur de la catapulte sous-marine à propulsion de la flèche sur la longueur du canon : PCT/FR/2004/001732 du 05/07/2004 est le montage d'un fil (a) lové dans le canal du sandow propulseur (b), figure 1 pour l'abrégé, ce fil sertis (d) aux extrémités du sandow propulseur (b) est allongé sur la flèche lors de son chargement, puis est mis sous haute tension (T) lors des chargements successifs des sandows tendeurs(g) sur les points d'appuis sous le fût de la catapulte. Ce système permet d'augmenter la tension (T) sur la flèche, en conséquence sa vitesse initiale, par rapport au même sandow (b) monté sans fil. De plus ce fil (a) résistant, souple, fin, mono filament ou non, gainé ou pas, sécurise le sandow propulseur d'une rupture et augmente sa longévité car le fil encaisse toute l'énergie des sandows tendeurs en bloquant l'extension du sandow propulseur et stocke toute l'énergie des sandows tendeurs, on a un meilleur rendement de la propulsion.

GROUNDING SLEEVE FOR ROTOR OF GENERATOR

INHIBITOR OF RETENTION OF FLAME FOR DIFFUSER Of FUEL INJECTION IN a GAS TURBINE

Inhibiteur (90) de rétention de flamme comportant une base (116) et un support dressé (107) s'écartant de la base ; au moins une languette (92) en forme d'aile delta sur le support dressé, chacune ayant une extrémité relativement pointue (96) et une extrémité relativement large (100).

Accelerator e.g. graphic card processor, designing method for e.g. civil industry, involves calculating costs for created aggregate accelerators from cost function, and selecting one of accelerators according to calculated cost

L'invention concerne un procédé pour la conception d'accélérateurs, dits accélérateurs agrégats, chacun d'eux étant adapté à au moins deux boucles (41,42) d'un programme, un accélérateur agrégat (12) comprenant des noeuds, correspondant à des éléments architecturaux (13,14,15,16,17), et des liens entre ces noeuds, ledit procédé de conception étant caractérisé en ce qu'il comporte les étapes suivantes : - la génération (31) d'accélérateurs spécialisés (43,44) adaptés auxdites boucles (41,42), - la création (32) d'au moins un accélérateur agrégat (45) à partir desdits accélérateurs spécialisés (43,44) et d'une base de données (49) d'éléments architecturaux prédéfinis (49.1), - le calcul (33) d'un coût pour chacun des accélérateurs agrégats (46) créés à partir d'une fonction de coût prédéfinie, - la sélection (34), en fonction du coût, d'un d'accélérateur agrégat parmi les accélérateurs créés.

USE OF the SULPHASALAZINE AND ITS METABOLITES FOR the MANUFACTURE Of a USEFUL DRUG IN the TREATMENT OF the VENOUS INSUFFICIENCY AND the VENOUS ULCERS

VOLATILE COMPOUNDS FOR THE TREATMENT OF [...]

THE TRIFUNCTIONAL CATALYTIC REDUCTION OF NOX IN DRY GAS TURBINE

CATALYTIC REDUCTION TRIFONCTIONNELLE DRY OF Nox Of a GAS TURBINE

VOLATILE COMPOUNDS FOR THE TREATMENT OF NEUROPALUDISME

LA PRESENTE INVENTION CONCERNE DES COMPOSES HALOGENE VOLATILS ANESTHESIQUES POUR LEUR UTILISATION DANS LE TRAITEMENT PREVENTIF ET CURATIF DES SYMPTOMES DU NEURO PALUDISME.

Fan e.g. centrifugal fan, for use in radiator of car, has obstacle for producing noise whose phase is opposite to that of selected tonal noise, where amplitude of obstacle noise is equal to that of tonal noise

Frustrated Lewis Pair Compositions

A compound having the formula (I) where each of R 1 , R 2 , R 3 and R 4 is independently C 6 -C 18 aryl-, C 5 -C 8 cycloalkyl-, C 6 -C 18 aryl having at least one C 1 -C 20 alkyl substituent, C 5 -C 8 cycloalkyl having at least one C 1 -C 20 alkyl sυbstituent, C 4 -C 20 branched alkyl-, C 16 -C 20 linear alkyl-, RO—, —NRR′, —PRR′, —SR, fluoro substituted forms thereof, and perfluoro forms thereof: and R 5 is C 6 -C 18 aryl-, C 5 -C 8 cycloalkyl-, C 6 -C 18 aryl having at least one C 1 -C 20 alkyl substituent, C 5 -C 8 cycloalkyl having at least one C 1 -C 20 alkyl substituent, C 3 -C 20 branched alkyl-, C 2 -C 30 linear alkyl-, fluoro substituted forms thereof, and perfluoro forms thereof; where R and R′ are each independently C 6 -C 18 aryl-, C 5 -C 8 cycloalkyl-, C 6 -C 18 aryl having at least one C 1 -C 20 alkyl substituent, C 5 -C 8 cycloalkyl having at least one C 1 -C 20 alkyl substituent, C 4 -C 20 branched alkyl-, C 2 -C 30 linear alkyl-, fluoro substituted forms thereof, and perfluoro forms thereof; A is N, P, S, or O with the proviso that when A is S, R 2 is a nullity; and M is B, Al, Ga or In.

Laser driver

An apparatus is provided. The apparatus includes a lasing element, a laser driver and logic. The laser driver is configured to drive the lasing element at multiple current levels, and the laser driver includes a switching network, multiple direct current (DC) loops, and an output circuit. The switching network receives a differential input signal, and each DC loop is coupled to the switching network. The output circuit is also coupled to the lasing element, and the logic is coupled to each of the DC current loops, where the logic selects one or more of the DC loops in each (of several) modes. Each mode generates one or more output lasing currents for the lasing element that corresponds to a one or more of the current levels in response to the differential input signal.

Compositions and methods for performing methylation detection assays

Provided herein is technology relating to performing methylation assays. In particular, the technology relates to internal controls for methylation assays.

Sampling device and analysis of methylated dna

The invention relates to cell sampling devices. In particular, the present invention relates to ingestible cell sampling devices for sampling cells in a subject, and methods of use for detecting abnormalities in a subject using the same. Provided herein is technology for neoplasia screening, and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of cancer.

Detecting cholangiocarcinoma

Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting neoplasms such as cholangiocarinoma.

Slidable waste management systems for cookboxes of grills

Slidable waste management systems for cookboxes of grills are disclosed. An example waste management system is configured to be coupled to a cookbox of a grill. The example waste management system includes a first guide rail and a second guide rail that are couplable to the cookbox, The example waste management system further includes a waste tray slidably coupled to the first guide rail and the second guide rail. The waste tray is movable between a closed configuration and an open configuration. The waste tray has an upper opening and a lower opening. The upper opening is configured to receive waste from the cookbox when the waste tray is in the closed configuration. The example waste management system further includes a waste bin coupled to and located below the waste tray. The waste bin is configured to receive the waste from the waste tray via the lower opening.

Method for Extending the Time Between Out-of-Service, In-Tank Inspections Using Ultrasonic Sensor

A method and apparatuses to extend the time interval between out-of-service, in-tank inspections while insuring structural integrity using a risk-based, Bayesian statistical approach comprised of a passing leak detection test and the using the results from (1) tank floor thickness measurements, (2) prior out-of-service tank floor inspection results, and/or (3) acoustic emission corrosion maps of the tank floor to estimate the minimum thickness and maximum corrosion rate of the tank during the extension period. The present invention uses an in-tank, mass-based leak detection system to establish tank integrity, three or more ultrasonic (UT) thickness measurement sensors for measurements of the tank floor at one location, and to establish the spatial distribution of corrosion of the tank floor, one or more prior API 653/12R1 or STI SP001 tank floor thickness inspections and/or three or more in-tank AE sensors mounted inside the tank with vertical and horizontal locations in an oblique plane relative to the tank floor.

Detecting colorectal neoplasm

Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting premalignant and malignant neoplasms such as colorectal cancer.

Detecting colorectal neoplasm

Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting premalignant and malignant neoplasms such as colorectal cancer.

System for controlling one or more locking web retractors in a motor vehicle occupant restraint system

A system is provided for controlling operation of an electrically controlled and magnetically actuated locking web retractor of an occupant restraint coupled to an occupant seat of a motor vehicle. A control circuit may monitor output signals produced by one or more sensors configured to produce one or more respective sensor output signals indicative of one or more corresponding sensed conditions of the motor vehicle, vehicle seat or occupant restraint, process the output signals produced by the one or more sensors to determine one or more values of the one or more sensed conditions, compare the one or more determined values of the one or more sensed conditions to one or more corresponding threshold or range values, and then provide a control signal, based on the one or more comparisons, to a magnet actuator of the web retractor to cause the web retractor to lock or unlock.

Compositions and methods for performing methylation detection assays

Provided herein is technology relating to performing methylation assays. In particular, the technology relates to internal controls for methylation assays.

Bis-phosphinimine catalyst

Organometallic complexes having two phosphinimine ligands and at least one activatable ligand are catalyst components for olefin polymerization. Preferred polymerization systems are prepared by combining the organometallic complexes with an ionic activator and/or an alumoxane. Preferred catalyst components contain titanium, zirconium, or hafnium and are activated with an ionic activator to form catalysts for ethylene polymerization.

Aluminum-phosphinimine complexes as catalysts for the (co)polymerization of ethylene

Aluminum-phosphinimine complexes function as a component in a catalyst system for the (co)polymerization of ethylene. The inventive catalyst components form a highly productive polymerization system when activated with so-called "ionic activators". The need for conventional transition metal catalyst metals (such as titanium, hafnium, zirconium or vanadium) is eliminated.

Cyclopentadienyl/phosphinimine catalyst with one and only one activatable ligand

Organometallic complexes of titanium or zirconium having only three ligands (namely a cyclopentadienyl ligand, a phosphinimine ligand and an activatable ligand) are catalyst components for olefin polymerization. Preferred polymerization systems are prepared by combining the organometallic complexes with an ionic activator and/or an alumoxane. Preferred catalyst components contain titanium (III) and are used in ethylene polymerization.

Bis-phosphinimine catalyst

Organometallic complexes having two phosphinimine ligands and at least one activatable ligand are catalyst components for olefin polymerization. Preferred polymerization systems are prepared by combining the organometallic complexes with an ionic activator and/or an alumoxane. Preferred catalyst components contain titanium, zirconium, or hafnium and are activated with an ionic activator to form catalysts for ethylene polymerization.

Bis-phosphinimine catalyst

Organometallic complexes having two phosphinimine ligands and at least one activatable ligand are catalyst components for olefin polymerization. Preferred polymerization systems are prepared by combining the organometallic complexes with an ionic activator and/or an alumoxane. Preferred catalyst components contain titanium, zirconium, or hafnium and are activated with an ionic activator to form catalysts for ethylene polymerization.

Supported phosphinimine-cp catalysts

A catalyst component which is especially useful in so-called "slurry" or "gas phase" olefin polymerizations and which comprises an organometallic complex of a group 4 metal (having a cyclopentadienyl-type ligand and a phosphinimine ligand) and a particulate support. The catalyst component forms an excellent catalyst system when combined with an activator such as an aluminoxane or a so-called "substantially non-coordinating anion". In a preferred embodiment the organometallic complex and the activator are both deposited on the particulate support.

Golf Bag Having Shoulder Strap With An Electronic Device

A golf bag having a shoulder strap with a pocket for housing an electronic device such as an MP3 player, a radio, CD player, cassette player, and like devices. The shoulder strap includes a speaker, controls, and wiring to connect the electronic device to the speaker.

Supported phosphinimine-Cp catalysts

A catalyst component which is especially useful in so-called "slurry" or "gas phase" olefin polymerizations and which comprises an organometallic complex of a group 4 metal (having a cyclopentadienyl-type ligand and a phosphinimine ligand) and a particulate support. The catalyst component forms an excellent catalyst system when combined with an activator such as an aluminoxane or a so-called "substantially non-coordinating anion". In a preferred embodiment the organometallic complex and the activator are both deposited on the particulate support.

Detecting colorectal neoplasm

Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting premalignant and malignant neoplasms such as colorectal cancer.

Detecting colorectal neoplasm

Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting premalignant and malignant neoplasms such as colorectal cancer.

Cyclopentadienyl/phosphinimine catalyst with one and only one activatable ligand

Organometallic complexes of titanium or zirconium having only three ligands (namely a cyclopentadienyl ligand, a phosphinimine ligand and an activatable ligand) are catalyst components for olefin polymerization. Preferred polymerization systems are prepared by combining the organometallic complexes with an ionic activator and/or an alumoxane. Preferred catalyst components contain titanium (III) and are used in ethylene polymerization.

Bis-phosphinimine catalyst

Organometallic complexes having two phosphinimine ligands and at least one activatable ligand are catalyst components for olefin polymerization. Preferred polymerization systems are prepared by combining the organometallic complexes with an ionic activator and/or an alumoxane. Preferred catalyst components contain titanium, zirconium, or hafnium and are activated with an ionic activator to form catalysts for ethylene polymerization.

Aluminum-phosphinimine complexes as catalysts for the (co)polymerization of ethylene

Aluminum-phosphinimine complexes function as a component in a catalyst system for the (co) polymerization of ethylene. The inventive catalyst components form a highly productive polymerization system when activated with so-called "ionic activators". The need for conventional transition metal catalyst metals (such as titanium, hafnium, zirconium or vanadium) is eliminated.

DNA encoding a novel RG1 polypeptide

The present invention relates to novel human extracellular matrix polypeptides, designated RG1, polynucleotides encoding the polypeptides, methods for producing the polypeptides, expression vectors and genetically engineered host cells for expression of the polypeptides. The invention further relates to methods for utilizing the polynucleotides and polypeptides in research, diagnosis, and therapeutic applications.

CENTRIFUGE CLUTCH, AND COVER MOUNT ASSEMBLY FOR THE SAME

Un embrague que tiene una pluralidad de miembros de leva entre una tapa y placa de presion para moverse hacia fuera bajo fuerza centrífuga y hacer que la placa de presion se mueva axialmente de modo de forzar una pluralidad de placas del embrague hacia un acoplamiento de embrague, un mecanismo de cancelacion manual para bloquear la placa de presion a efectos de mantener las placas de presion en una posicion desacoplada, y resortes limitadores de la presion impiden que las cargas de impacto se impartan a las placas de embrague cuando las placas son hechas avanzar hacia un acoplamiento de embrague entre sí. La carcaza del embrague incluye una tapa que puede montarse sea a ras sea quedar rehundida en paredes circunferencialmente separadas entre sí de la carcaza, y puede mantenerse en su lugar mediante un anillo de retencion insertado en ranuras en las paredes laterales, y es adaptable para utilizarse con cualquier tipo de embrague, con o sin el mecanismo de cancelacion manual y resortes limitadores de la presion. A clutch having a plurality of cam members between a cover and pressure plate to move out under centrifugal force and cause the pressure plate to move axially so as to force a plurality of clutch plates towards a clutch coupling, a manual cancellation mechanism to lock the pressure plate in order to keep the pressure plates in an uncoupled position, and pressure limiting springs prevent the impact loads from being imparted to the clutch plates when the plates are advanced towards a clutch coupling with each other. The clutch housing includes a cover that can be mounted flush or recessed into circumferentially separated walls of the carcass, and can be held in place by a retaining ring inserted into grooves in the side walls, and is adaptable for use with any type of clutch, with or without the manual cancellation mechanism and pressure limiting springs.

Supported phosphinimine-cyclopentadienyl catalysts

A catalyst component which is especially useful in so-called "slurry" or "gas phase" olefin polymerizations and which comprises an organmetallic complex of a froup 4 metal (having a cyclopentadienyl ligand and a phosohinimine ligand) and a particulate support. The catalyst component forms an excellent catalyst system when combined with an activator such as an aluminoxane or a so-called "substantially non-coordinating anion". In a preferred embodiment the organometallic complex and the activator are both deposited on the particulate support.

High temperature solution polymerization process

Supported phosphinimine-cyclopentadienyl catalysts

High temperature solution polymerization process

This invention is a solution process for the preparation of high molecular weight ethylene copolymers comprising contacting olefin monomers, with a catalyst system at a polymerization temperature at or above about 80.degree.C with a catalyst system comprising an unbridged Group 4 metal compound having a monocyclopentadienyl ligand, a phosphinimine ligand and at least one uninegative, activation reactive ligand. The process can be practiced at a reaction temperature of at least 80.degree.C to obtain high number average molecular weight polymer.</S DOAB>

Bis-phosphinimine catalyst

Organometallic complexes having two phosphinimine ligands and at least one activatable ligand are catalyst components for olefin polymerization. Preferred polymerization systems are prepared by combining the organometallic complexes with an ionic activator and/or an alumoxane. Preferred catalyst components contain titanium, zirconium, or hafnium and are activated with an ionic activator to form catalysts for ethylene polymerization.

High temperature solution polymerization process

A solution process for the preparation of high molecular weight ethylene copolymers comprising contacting olefin monomers, with a catalyst system at a polymerization temperature at or above about 80°C with a catalyst system comprising an unbridged Group 4 metal compound having a monocyclopentadienyl ligand, a phospihinimine ligand and at least one uninegative, activation reactive ligand. The process can be practised at a reaction temperature of at least 80°C to obtain high number average molecular weight polymer.

High temperature solution polymerization process

This invention is a solution process for the preparation of high molecular weight ethylene copolymers comprising contacting olefin monomers, with a catalyst system at a polymerization temperature at or above about 80.degree.C with a catalyst system comprising an unbridged Group 4 metal compound having a monocyclopentadienyl ligand, a phosphinimine ligand and at least one uninegative, activation reactive ligand. The process can be practiced at a reaction temperature of at least 80.degree.C to obtain high number average molecular weight polymer.

Supported phosphinimine-cp catalysts

A catalyst component which is especially useful in so-called "slurry" or "gas phase" olefin polymerizations and which comprises an organometallic complex of a group 4 metal (having a cyclopentadienyl-type ligand and a phosphinimine ligand) and a particulate support. The catalyst component forms an excellent catalyst system when combined with an activator such as an aluminoxane or a so-called "substantially non-coordinating anion". In a preferred embodiment the organometallic complex and the activator are both deposited on the particulate support.

Polymerization catalyst having a phosphinimine ligand

This invention is a solution process for the preparation of high molecular weight ethylene copolymers comprising contacting olefin monomers, with a catalyst system at a polymerization temperature at or above about 80° C. with a catalyst system comprising an unbridged Group 4 metal compound having a monocyclopentadienyl ligand, a phosphinimine ligand and at least one uninegative, activation reactive ligand. The process can be practiced at a reaction temperature of at least 80° C. to obtain high number average molecular weight polymer.

Hydrocarbyl phosphinimine/cyclopentadienyl complexes of group IV metals and preparation thereof

New group 4 organometallic complexes are characterized by having a phosphinimine ligand and two or more cyclopentadienyl ligands. Certain of these complexes exhibit unusual behavior when examined by nuclear magnetic resonance (NMR) techniques. Well defined crystals of the inventive complexes have been isolated and analyzed by x-ray crystallography. The complexes have also been found to be polymerization catalysts which are surprisingly more active than their simple metallocene analogs.

Hydrocarbyl phosphinimine/cyclopentadienyl complexes of group iv metals and preparation thereof

New group 4 organometallic complexes are characterized by having a phosphinimine ligand and two or more cyclopentadienyl ligands. Certain of these complexes exhibit unusual behavior when examined by nuclear magnetic resonance (NMR) techniques. Well defined crystals of the inventive complexes have been isolated and analyzed by x-ray crystallography. The complexes have also been found to be polymerization catalysts which are surprisingly more active than their simple metallocene analogs.

Bis-phosphinimine catalyst

Organometallic complexes having two phosphinimine ligands and at least one activatable ligand are catalyst components for olefin polymerization. Preferred polymerization systems are prepared by combining the organometallic complexes with an ionic activator and/or an alumoxane. Preferred catalyst components contain titanium, zirconium, or hafnium and are activated with an ionic activator to form catalysts for ethylene polymerization.

Bis-phosphinimine catalyst

Organometallic complexes having two phosphinimine ligands and at least one activatable ligand are catalyst components for olefin polymerization. Preferred polymerization systems are prepared by combining the organometallic complexes with an ionic activator and/or an alumoxane. Preferred catalyst components contain titanium, zirconium, or hafnium and are activated with an ionic activator to form catalysts for ethylene polymerization.

Aluminum-phosphinimine complexes as catalysts for the (co)polymerization of ethylene

Aluminum-phosphinimine complexes function as a component in a catalyst system for the (co) polymerization of ethylene. The inventive catalyst components form a highly productive polymerization system when activated with so-called "ionic activators". The need for conventional transition metal catalyst metals (such as titanium, hafnium, zirconium or vanadium) is eliminated.

Hydrocarbyl phosphinimine/cyclopentadienyl complexes of group iv metals and preparation thereof

New group 4 organometallic complexes are characterized by having a phosphinimine ligand and two or more cyclopentadienyl ligands. Certain of these complexes exhibit unusual behavior when examined by nuclear magnetic resonance (NMR) techniques. Well defined crystals of the inventive complexes have been isolated and analyzed by x-ray crystallography. The complexes have also been found to be polymerization catalysts which are surprisingly more active than their simple metallocene analogs.

Cyclopentadienyl /phosphinimine catalyst with one and only one activatable ligand

Cyclopentadienyl /phosphinimine catalyst with one and only one activatable ligand

Organometallic complexes of titanium or zirconium having only three ligands (namely a cyclopentadienyl ligand, a phosphinimine ligand and an activatable ligand) are catalyst components for olefin polymerization. Preferred polymerization systems are prepared by combining the organometallic complexes with an ionic activator and/or an alumoxane. Preferred catalyst components contain titanium (III) and are used in ethylene polymerization.

Cyclopentadienyl /phosphinimine catalyst with one and only one activatable ligand

Organometallic complexes of titanium or zirconium having only three ligands (namely a cyclopentadienyl ligand, a phosphinimine ligand and an activatable ligand) are catalyst components for olefin polymerization. Preferred polymerization systems are prepared by combining the organometallic complexes with an ionic activator and/or an alumoxane. Preferred catalyst components contain titanium (III) and are used in ethylene polymerization.

Cyclopentadienyl/phosphinimine catalyst with one and only one activatable ligand

Organometallic complexes of titanium or zirconium having only three ligands (namely a cyclopentadienyl ligand, a phosphinimine ligand and an activatable ligand) are catalyst components for olefin polymerization. Preferred polymerization systems are prepared by combining the organometallic complexes with an ionic activator and/or an alumoxane. Preferred catalyst components contain titanium (III) and are used in ethylene polymerization.

Hydrocarbyl phosphinimine/cyclopentadienyl complexes of group 4 and their use in olefin polymerization

New group 4 organometallic complexes are characterized by having a phosphinimine ligand and two or more cyclopentadienyl ligands. Certain of these complexes exhibit unusual behavior when examined by nuclear magnetic resonance (NMR) techniques. Well defined crystals of the inventive complexes have been isolated and analyzed by x-ray crystallography. The complexes have also been found to be polymerization catalysts which are surprisingly more active than their simple metallocene analogs.

Wettable polyolefin fibers and fabrics

Polyolefin woven and nonwoven fibers, filaments and fabrics made therefrom which comprise a melt blend which comprises (a) a polyolefin; and (b) at least one compound of the formula (I) R 1 —(hydrophilic oligomer)  (I) wherein R 1 is a straight or branched chain alkyl of 22 to 40 carbon atoms and the hydrophilic oligomer is a homo- or co-oligomer consisting of monomer units derived from monomers selected from the group consisting of ethylene oxide, propylene oxide, ethylene glycol, propylene glycol, epichlorhydrin, acrylic acid, methacrylic acid, ethylene imine, caprolactone, vinyl alcohol and vinyl acetate; and wherein the hydrophilic oligomer consists of between 2 and 10 monomer units, exhibit excellent durable wettability. The fabrics are useful in disposable diapers, training pants, feminine napkins, tampons, incontinence care products, wet and dry wipes, wound dressings, surgical capes, filter medial, battery separators and the like.

Stabilized ethylene-vinyl acetate copolymer hot melt adhesive systems

Hot melt adhesive compositions stabilized against thermal degradation, discoloration, skin formation and substantial viscosity changes, said adhesives being based on ethylene-vinyl acetate copolymer and a hydrocarbon tackifying resin and containing a stabilizer system of a hindered phenol antioxidant, a phosphite costabilizer and an acid scavenger.

Selecting information for ad hoc exchange

A method for organizing an exchange of information between software agents includes for each of the software agents: establishing a semantic information network; receiving a trigger signal; performing a search of the semantic information network; and performing actions related to the trigger signal. A system and a computer program product for implementing the method are provided.

Supported phophinimime-cyclopentadienyl catalysts

Compensation system and related techniques for use in a printed circuit board inspection system

A system and method for compensating pixel values in an inspection machine for inspecting printed circuit boards includes an image acquisition system for providing pixel values from a digitized image to a compensation circuit. The compensation circuit applies one or more compensation values to the digitized pixel values to provide compensated digitized pixel values for storage in a memory. The compensated digitized pixel values are then available for use by an image processor which implements inspection techniques during a printed circuit board manufacturing process. With this technique, the system corrects the errors on a pixel by pixel basis as the pixel values representing an image of a printed circuit board are transferred from the image acquisition system to the memory.

Sulfhydryl containing tricyclic lactams and their pharmacological methods of use

This invention relates to conformationally rigid sulfur containing tricyclic lactams of the formula

Control valve for nitrous oxide injection system

A nitrous oxide or fuel control valve has flow control of nitrous oxide from a fluid-delivery aperture ( 7 ) or flow control of fuel from a fluid-delivery aperture ( 8 ) into a injection nozzle ( 22 ) of an intake manifold of an engine by actuation of an adjuster coupler nut ( 11 ) with an actuation piston ( 14 ) that is actuated with gas pressure from an actuation-pressure source ( 43 ) with an actuation on/off valve( 25 ). It can be structured for low-weight, short-term needs for racing and other sports uses or for heavier long-term needs of engines.

Detecting neoplasm

Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting premalignant and malignant neoplasms such as pancreatic and colorectal cancer.

Detecting esophageal disorders

Provided herein is technology for esophageal disorder screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of esophageal disorders (e.g., Barrett's esophagus, Barrett's esophageal dysplasia, etc.). In addition, the technology provides methods, compositions and related uses for distinguishing between Barrett's esophagus and Barrett's esophageal dysplasia, and between Barrett's esophageal low-grade dysplasia, Barrett's esophageal high-grade dysplasia, and esophageal adenocarcinoma within samples obtained through endoscopic brushing or nonendoscopic whole esophageal brushing or swabbing using a tethered device (e.g. such as a capsule sponge, balloon, or other device).

Detecting hepatocellular carcinoma

Provided herein is technology for hepatocellular carcinoma screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of hepatocellular carcinoma.

Compositions and methods for performing methylation detection assays

Provided herein is technology relating to performing methylation assays. In particular, the technology relates to internal controls for methylation assays.

Detecting neoplasm

Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting premalignant and malignant neoplasms such as pancreatic and colorectal cancer. Accordingly, provided herein is technology for pancreatic cancer screening markers and other gastrointestinal cancer screening markers that provide a high signalto- noise ratio and a low background level when detected from samples taken from a subject (e.g., stool sample). As described herein, the technology provides a number of methylated DNA markers and subsets thereof (e.g., sets of 2, 3, 4, 5, 6, 7, 8, 9, 10, 1 1, 12 or more markers) with high discrimination for GI neoplasms overall and/or at individual tumor sites.

Detecting neoplasm

Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting premalignant and malignant neoplasms such as pancreatic and colorectal cancer. Accordingly, provided herein is technology for pancreatic cancer screening markers and other gastrointestinal cancer screening markers that provide a high signalto- noise ratio and a low background level when detected from samples taken from a subject (e.g., stool sample). As described herein, the technology provides a number of methylated DNA markers and subsets thereof (e.g., sets of 2, 3, 4, 5, 6, 7, 8, 9, 10, 1 1, 12 or more markers) with high discrimination for GI neoplasms overall and/or at individual tumor sites.

Detecting colorectal neoplasm

Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting premalignant and malignant neoplasms such as colorectal cancer.

Compositions and methods for performing methylation detection assays

Provided herein is technology relating to performing methylation assays. In particular, the technology relates to internal controls for methylation assays.

Detecting gastric neoplasm

Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting premalignant and malignant neoplasms such as gastric cancer.

Detecting gastrointestinal neoplasms

Provided herein is technology for gastrointestinal neoplasia screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of gastrointestinal neoplasm, and classifying the site location of such a gastrointestinal neoplasm (e.g., a colorectal region, a pancreaticobiliary region, a gastroesophageal region).

Detecting cholangiocarcinoma

Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting neoplasms such as cholangiocarinoma.

Detecting colorectal neoplasia

Provided herein is technology for colorectal neoplasia screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of colorectal neoplasia in 1) individuals at, older or younger than 50 years of age, or 2) individuals having Lynch Syndrome.

Detecting prostate cancer

Provided herein is technology for prostate cancer screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of prostate cancer.

Detecting breast cancer

Provided herein is technology for breast cancer screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of breast cancer.

Detecting pancreatic high-grade dysplasia

Provided herein is technology for pancreatic high-grade dysplasia screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of pancreatic high-grade dysplasia (IPMN-HGD, PanIN-3, or PDAC).

Detecting neoplasm

Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting premalignant and malignant neoplasms such as pancreatic and colorectal cancer.

Detecting neoplasm

Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting premalignant and malignant neoplasms such as pancreatic and colorectal cancer.

Detecting neoplasm

Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting premalignant and malignant neoplasms such as pancreatic and colorectal cancer. Accordingly, provided herein is technology for pancreatic cancer screening markers and other gastrointestinal cancer screening markers that provide a high signal to-noise ratio and a low background level when detected from samples taken from a subject (e.g., stool sample). As described herein, the technology provides a number of methylated DNA markers and subsets thereof (e.g., sets of 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12 or more markers) with high discrimination for G1 neoplasms overall and/or at individual tumor sites.

Detecting neoplasm

Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting premalignant and malignant neoplasms such as pancreatic and colorectal cancer.

Detecting colorectal neoplasm

Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting premalignant and malignant neoplasms such as colorectal cancer.

Detecting colorectal neoplasm

Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting premalignant and malignant neoplasms such as colorectal cancer.

Detecting colorectal neoplasm

Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting premalignant and malignant neoplasms such as colorectal cancer.

Detecting colorectal neoplasm

Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting premalignant and malignant neoplasms such as colorectal cancer.

Detecting cholangiocarcinoma

Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting neoplasms such as cholangiocarcinoma.

Detecting gastrointestinal neoplasms

Provided herein is technology for gastrointestinal neoplasia screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of gastrointestinal neoplasm, and classifying the site location of such a gastrointestinal neoplasm (e.g., a colorectal region, a pancreaticobiliary region, a gastroesophageal region).

Detecting gastrointestinal neoplasms

Provided herein is technology for gastrointestinal neoplasia screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of gastrointestinal neoplasm, and classifying the site location of such a gastrointestinal neoplasm (e.g., a colorectal region, a pancreaticobiliary region, a gastroesophageal region).

Detecting esophageal disorders

Provided herein is technology for esophageal disorder screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of esophageal disorders (e.g., Barrett's esophagus, Barrett's esophageal dysplasia, etc.). In addition, the technology provides methods, compositions and related uses for distinguishing between Barrett's esophagus and Barrett's esophageal dysplasia, and between Barrett's esophageal low-grade dysplasia, Barrett's esophageal high-grade dysplasia, and esophageal adenocarcinoma within samples obtained through endoscopic brushing or nonendoscopic whole esophageal brushing or swabbing using a tethered device (e.g. such as a capsule sponge, balloon, or other device).

Detecting esophageal disorders

Provided herein is technology for esophageal disorder screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of esophageal disorders (e.g., Barrett's esophagus, Barrett's esophageal dysplasia, etc.). In addition, the technology provides methods, compositions and related uses for distinguishing between Barrett's esophagus and Barrett's esophageal dysplasia, and between Barrett's esophageal low-grade dysplasia, Barrett's esophageal high-grade dysplasia, and esophageal adenocarcinoma within samples obtained through endoscopic brushing or nonendoscopic whole esophageal brushing or swabbing using a tethered device (e.g. such as a capsule sponge, balloon, or other device).

Detecting gastric neoplasm

Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting premalignant and malignant neoplasms such as gastric cancer.

Detecting breast cancer

Provided herein is technology for breast cancer screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of breast cancer.

Multistep synthesis of hexafluoropropylene

The present invention relates to multistep syntheses of hexafluoropropylene from hexachloropropylene. In all these syntheses the first step is a fluorination of the starting material; later steps convert the initial products to CF 3 --CFCl--CF 3 , which is dehalogenated to the desired product.

Remote unmanned work system (RUWS) electromechanical cable system

A tethered underwater work system comprises a primary lift module attachedo a support vehicle by means of a primary tether. A submarine work vehicle is removably attached to said primary lift module and connected thereto by means of a secondary tether. Additionally, the lift module contains electrical distribution systems to permit an extensive control and instrumentation linkage with the submarine work vehicle and remotely controlled manipulators mounted thereon.

Complete trip system

The present invention discloses apparatus and methods for perforating, completing, testing, and abandoning a wellbore in a single trip. One embodiment of the invention is a method that comprises perforating an interval within the wellbore, positioning a sand screen assembly adjacent the perforated interval, gravel packing the perforated interval, performing testing on the perforated interval, and then abandoning the well, all in a single trip in the wellbore.

N,N',N''-tris{2,4-bis Hydrocarbyloxy-2,2,6,6-tetra-methylpiperidin-4-yl)alkylamino!-s-triazin-6-yl}-3,3'-ethylenediiminodipropylamines, their isomers and bridged derivatives and polymer compositions stabilized therewith

A mixture of the compounds identified in the title, their pure isomers and alkane-bridged derivatives are particularly effective in stabilizing polymer compositions, particularly polyolefin compositions.

Off-axis straps for a golf bag

Golf bags including a single, off-axis strap arrangement or a dual, off-axis strap arrangement are disclosed. In single, off-axis arrangements, the strap is arranged such that each end of the strap is connected to the golf bag on opposite sides of a spinal axis, wherein one end of the strap is connected proximate an open top end and the other strap is connected intermediate the open top end and a closed bottom end. In dual, off-axis strap arrangements, each end of each strap is connected on opposite sides of the spinal axis, wherein each strap has one end connected proximate an open top end and one end connected intermediate the open top end and a closed bottom end. In addition, the end of each strap that is connected proximate the open top end is connected asymmetrical to each other with respect to a spinal axis of the golf bag.

Re-entrant cannula device

TITLE A RE-ENTRANT CANNULA DEVICE INVENTORS MICHAEL IVAN DOUGLAS W. JOHNSTON ABSTRACT OF THE DISCLOSURE A re-entrant cannula device for use in the proximal duodenum and/or the site to terminal ileum of, for example, sheep and pigs, which comprises a casing of resilient material and a cylindrical plug cock which is pressed into the casing and has two digesta passages extending through the cylindrical plug cock along sep-arate, isolated, curved paths, The casing has two, splayed intestine connectors and the cylindrical plug cock is rotated, by a connector tube in one digesta pas-sage, from a "maintenance" position wherein digesta flows through one connector, along one digesta passage in the cylindrical plug cock and back to the intestine through the other connector, to a "collection" position where digesta flows from one connector along one digesta pas-cage for collection and is returned to the intestine along the other digesta passage and connector back to the intestine.

Surgical clip applier

A surgical clip applier includes a housing, a pair of handles pivotably connected to opposite sides of the housing, a channel assembly which is anchored to the housing and a jaw assembly which is anchored to the channel assembly. The jaws are opened and closed by a cam plate which is slidably positioned in the channel assembly and is provided with cam slots at its distal end to engage drive rivets positioned on the jaw members. A pusher bar assembly is also provided to feed clips from a series of clips to the jaw mechanism, and the instrument operates such that all moving components move in the same direction during the closing stroke of the handle, and then move in the same direction opposite to the closing direction when the handles are in the opening stroke. A novel lockout mechanism is also provided to render the instrument inoperable after all the clips have been utilized from the instrument.

Art and composition

Conversion of biomass feedstock to diesel fuel additive

A process is described for producing additives for diesel fuels having high cetane numbers and serving as fuel ignition improvers. In the process, biomass feedstock selected from (a) tall oil containing less than 0.5 wt % ash, less than 25 wt % unsaponifiables, up to 50 wt % diterpenic acids and 30 to 60 wt % unsaturated fatty acids, (b) wood oils from the pulping of hardwood species, (c) animal fats and (d) blends of said tall oil with plant or vegetable oil containing substantial amounts of unsaturated fatty acids or animal fats, is subjected to hydroprocessing by contacting the feedstock with gaseous hydrogen under hydroprocessing conditions in the presence of a hydroprocessing catalyst to obtain a product mixture. This product mixture is then separated and fractionated to obtain a hydrocarbon product boiling in the diesel fuel boiling range, this product being the high cetane number additive.

Fae1 genes and their uses

The present invention provides polynucleotide sequences from FAE1 genes. FAE1 genes encode elongation enzymes which catalyze the conversion of C18 FAs to C20-C22 FAs. The polynucleotides of the invention are used to modify FAE1 gene expression and thereby modulate FA content in plant organs or parts, particularly seeds.

2-mercaptomethylene-tetrahydronaphthalene and indane-2-carboxamide derivatives as enkephalinase inhibitors

This invention relates to novel 2-mercaptomethylene-tetrahydronaphthalene derivatives of the formula (see formula I) wherein n is an integer 2, Z is the radical -C(O)OR, or a phenyl group unsubsti-tuted or substituted with from 1 to 3 substituents selected from the group consisting of OH, C1-C4 alkoxy, and methylenedioxy, R is H, C1-C4 alkyl, or benzyl, R1 is H or -C(O)-A, wherein A is C1-C4 alkyl, or phenyl, and B is a radical of the formula <see formula II or III> wherein m is an integer 0 to 5, and R2 is H, C1-C4 alkyl, -CH2-OH, -CH(OH)-CH3, -CH2CH2SCH3, phenylmethyl, 4-hydroxy-phenylmethyl or OH, with the proviso that R2 cannot be OH when m is 0, which are useful as enkephalinase inhibitors.

Variable diameter rod protector.

L'invention concerne un protecteur de tige à diamètre variable qui empêche un glissement sur une tige sous-dimensionnée, qui peut aussi être utilisé sur une tige de dimension normale et qui comprend un élément tubulaire (10) en caoutchouc, une ouverture (24) sur la longueur de l'élément tubulaire en caoutchouc, capable de s'écarter pour faciliter l'installation sur la tige, un moyen de fermeture (26) pour fixer l'élément tubulaire en caoutchouc sur la tige et au moins une bande en caoutchouc détachable (12, 14, 16) fixée sur la surface interne de l'élément tubulaire en caoutchouc au niveau d'un point de fixation (18, 20, 22). A variable diameter shank protector which prevents slipping on an undersized shank, can also be used on a full size shank, and includes a tubular member (10) of rubber, an opening (24). along the length of the tubular rubber member, capable of pulling apart to facilitate installation on the rod, a closure means (26) for securing the tubular rubber member to the rod and at least one rubber band detachable (12, 14, 16) attached to the inner surface of the tubular rubber member at an attachment point (18, 20, 22).

Characterizing methylated dna, rna, and proteins in subjects suspected of having lung neoplasia

Provided herein is technology relating to detecting neoplasia and particularly, but not exclusively, to methods, compositions, and related uses for detecting neoplasms such as lung cancer.

Detecting pancreatic neuroendocrine tumors

Provided herein is technology for pancreatic neuroendocrine tumor screening and particularly, but not exclusively, to methods, compositions, and related uses for detecting the presence of pancreatic neuroendocrine tumors.

Amino and nitro containing tricyclic compounds useful as inhibitors of ace

The present invention relates to compounds of the formula ##STR1## wherein A is methylene, oxygen, sulfur or N--B wherein B is R 1 or COR 2 wherein R 1 is hydrogen, a C 1 -C 4 alkyl or an Ar--Z-- group wherein Ar is aryl and Z is a C 0 -C 4 alkyl and R 2 is a --CF 3 , a C 1 -C 10 alkyl or an Ar--Z group; R is hydrogen or a C 1 -C 4 alkyl; and X and Y are each independently hydrogen, nitro or amino, with the proviso that when X is nitro or amino, Y must be hydrogen, and when Y is nitro or amino, X must be hydrogen; and pharmaceutically acceptable salts thereof, which are inhibitors of Angiotensin Converting Enzyme.

Devices to access peripheral regions of the lung for direct visualization with tool attachment

The present disclosure relates generally to the field of medical devices. In particular, the present disclosure relates to modular assemblies, systems and methods for direct visualization and biopsy of peripheral pulmonary nodules. In one example, a modular assembly of the present disclosure may include a dual-lumen catheter attached to a distal end of a main body, a first lumen may extend through the main body, the first lumen contiguous with a first lumen of the dual-lumen catheter, a second lumen may extend through the main body, the second lumen contiguous with a second lumen of the dual-lumen catheter and an attachment member formed within the main body at a proximal end of the second lumen.

Amino and nitro containing tricyclic compounds useful as inhibitors or ace

The present invention relates to compounds of the formula (see formula I) wherein A is methylene, oxygen, sulfur or N-B wherein B is R1 or COR2 wherein R1 is hydrogen, a C1-C4 alkyl or an Ar-Z-group wherein Ar is aryl and Z is a C0-C4 alkyl and R2 is a -CF3, a C1-C10 alkyl or an Ar-Z group; R is hydrogen ar a C1-C4 alkyl; and X and Y are each independently hydrogen, nitro or amino, with the proviso that when X is nitro or amino, Y must be hydrogen, and when Y is nitro or amino, X must be hydrogen; and pharmaceutically acceptable salts thereof, which are inhibitors of Angiotensin Converting Enzyme.