SYSTEM AND PROCESS FOR THE REEMISSION OF DATA OF UPLINK IN A COMMUNICATION SYSTEM HAVE ACCESS MULTIPLE BY DISTRIBUTION BY CODE

PROCEEDED WITH GENERATION Of a RADIATION WISHED WAVELENGTHS, ETDISPOSITIF ASSOCIATES

MAGNETIC CERAMIC COMPOSITION FOR the USE IN DEVICES HAS MICROWAVES, MAGNETIC CERAMICS FOR the USE IN DEVICES HAS MICROWAVES AND ITS METHOD OF PREPARATION

TOGETHER OF FRONT PANEL FOR MICROWAWE OVEN AND PROCEEDED Of ASSEMBLY OF THIS UNIT

Apparatus of formation of image.

PLUG STRUCTURE OF THE CONTAINER.

PLUG STRUCTURE OF THE CONTAINER.

La présente invention concerne la structure de bouchage d'un récipient, qui est accouplé avec ledit récipient pour fermer/ouvrir ledit récipient. La structure de bouchon comprend un bouchon interne ayant cylindrique et accouplé avec une partie d'extrémité supérieure du récipient pour ouvrir/fermer le récipient, un bouchon externe cylindrique et inséré dans la surface extérieure du bouchon interne, de telle sorte que le bouchon externe est accouplée avec le bouchon interne, un élément inséré dans le bouchon externe et le bouchon interne et une unité amovible afin d'accoupler de manière fixe le composant avec le bouchon interne ou le bouchon externe ou séparer le composant avec le bouchon interne ou le bouchon externe sans séparer le bouchon interne ou le bouchon externe du récipient. En conclusion, le bouchon peut ouvrir/fermer le récipient de manière de fixer l'élément au bouchon ou de le démonter du bouchon sans séparer le bouchon du récipient.

EARTHQUAKE RESISTANT LID FOR CONTAINER TRANSPORTATION OF NUCLEAR FUEL ASSEMBLY AND SHIPPING CONTAINER FOR NUCLEAR FUEL ASSEMBLIES

METHOD FOR INTEGRATED MONITORING FOR A NUCLEAR DEVICE AND SYSTEM USING SAME

ARRAY SUBSTRATE, MANUFACTURING METHOD THEREOF AND LIQUID CRYSTAL DISPLAY DEVICE HAVING THE SAME

DISPLAY DEVICE AND METHOD OF MAKING SAME.

VERTICAL VIBRATOR

NANOPARTICULE HETERONUCLEAIRE OF RADIOISOTOPE HAS STRUCTURE NOYAU-COQUE AND ITS METHOD OF PREPARATION.

L'invention concerne une nanoparticule hétéronucléaire de radio-isotope à structure noyau-coque et son procédé de préparation. La nanoparticule hétéronucléaire de radio-isotope à structure noyau-coque comprend : un noyau contenant deux radio-isotopes différents choisis parmi198Au,63Ni,110mAg,64Cu,60Co,192Ir et103Pd ; et une coque de SiO2 entourant le noyau. La nanoparticule hétéronucléaire de radio-isotope à structure noyau-coque peut être utilisée comme traceur pour détecter une variation de rapport volumique ou pour évaluer les caractéristiques du comportement d'une ressource en eau, sur la base d'informations concernant le rapport de phase dans l'écoulement d'un fluide à plusieurs phases existant dans un procédé qui est mis en œuvre dans des conditions extrêmes telles qu'une température élevée et/ou une pression élevée.

COMMUNICATION SYSTEM FOR ENGINE HAS TURBINE

Système de communication (30), comprenant un capteur (25) servant à mesurer un état à un point de mesure concerné (20) défini sur un rotor (12) d'une turbine (10), à une certaine distance radiale d'un axe central (122) autour duquel peut tourner le rotor (12), des câblages disposés sur le rotor (12), à une certaine distance radiale de l'axe central (122), les câblages comprenant un premier tronçon de câblages (40) relié au capteur (25), un second tronçon de câblages (60) et une première connexion (50) par laquelle les premier et second tronçons de câblages (40, 60) peuvent être connectés, une seconde connexion (70) par laquelle le second tronçon de câblages (60) transmet un signal reflétant l'état détecté à un élément d'enregistrement non rotatif (75), et un module de compensation (65) de température disposé sur le second tronçon de câblage (60) pour régler le signal.

DISPLAY DEVICE, DEVICE OF REMOTE CONTROL AND RELATED FUNCTION OF ORDER

Un dispositif de commande à distance est proposé. Le dispositif de commande à distance destiné à sélectionner l'un d'une pluralité de modes d'exploitation d'un dispositif d'affichage externe étant exploitable entre un mode de pointage et un mode gestuel, associé au dispositif de commande à distance. Le dispositif de commande à distance inclut une unité de génération en sortie destinée à générer en sortie des informations connexes au dispositif de commande à distance, vers le dispositif externe, une unité de détection destinée à détecter le mouvement du dispositif de commande à distance, une unité de génération d'informations de mouvement destinée à générer des informations de mouvement sur la base du mouvement détecté du dispositif de commande à distance, une unité de changement de mode d'exploitation destinée à fournir des informations connexes à un mode d'exploitation, en vue de modifier le mode d'exploitation du dispositif externe exploitable entre le mode de pointage et le mode gestuel ...

Decoration kit type door assembly for e.g. refrigerator, has handle integral part of one of left or right side metallic covers, where handle has curved plate extending in longitudinal direction of cover in order to define hollow of cover

L'invention concerne un ensemble porte (100) du type à kit de décoration destiné à un produit électronique. Dans l'ensemble porte (100) comprenant des plaques de porte (10) et des couvercles latéraux gauche et droit (20a et 20b) couplés aux deux côtés des plaques de porte (10), une poignée (22b) de porte d'ouverture/de fermeture fait partie intégrante de l'un des couvercles latéraux gauche et droit (20a et 20b), entraînant une réduction des coûts de fabrication. De même, lorsque la poignée (22b) de porte du couvercle latéral a la forme d'une partie en creux (23b') définie intégralement dans le couvercle latéral de manière à ne pas faire saillie vers l'extérieur du couvercle latéral, l'ensemble porte (100) résultant donne une apparence extérieure satisfaisant aux demandes d'esthétisme des consommateurs.

Display device e.g. LCD device, has signal line connecting another signal line to driving circuit, where signal lines are formed in conductive-layer structure by interposing insulation layer between lower and upper lines

Un dispositif d'affichage comprend un circuit de pilotage formé sur un substrat ; au moins une première ligne de signaux (103) comportant des lignes inférieure (100) et supérieure (102) se chevauchant entre elles avec une couche d'isolation intercalée entre elles, la première ligne de signaux (103) étant formée au niveau d'un côté du circuit de pilotage ; et au moins une deuxième ligne de signaux (201) pour raccorder la première ligne de signaux (103) au circuit de pilotage. Application à un dispositif d'affichage à cristaux liquides (LCD) empêchant des défauts provoqués par déconnexion d'une ligne de signaux.

OXIDATIVE DECONTAMINATION REAGENT FOR REMOVING RADIOACTIVE DENSE OXIDE LAYER ON A METAL SURFACE AND OXIDATIVE DECONTAMINATION METHOD USING THE SAME

La présente invention concerne un réactif de décontamination oxydative pour l'élimination de la couche d'oxyde radioactif dense sur la surface métallique, le réactif comprenant un agent d'oxydation, un ion métallique, et un acide inorganique. Le réactif de décontamination oxydative de la présente invention est caractéristiquement préparé par ajout d'un ion métallique au réactif de décontamination oxydative classique contenant un agent d'oxydation et un acide inorganique. Lorsque le réactif de décontamination oxydative de la présente invention est utilisé, le potentiel électrique des parties métalliques du système primaire de la centrale nucléaire peut être régulé comme un potentiel passif en raison de l'ion métallique ajouté pendant la décontamination oxydative de la partie métallique primaire de la centrale nucléaire. Il est par conséquent possible d'inhiber la corrosion locale tout en réduisant significativement les déchets secondaires par le maintien du potentiel électrique de la partie ...

MULTIPLEXED MICROVOLT SENSOR SYSTEMS

L'invention concerne des systèmes et des procédés à capteur microvolt multiplexé. Un exemple de système peut comprendre une source lumineuse à impulsions, un premier segment optique guide d'onde couplé en fonctionnement à la source lumineuse à impulsions, un circulateur optique (104) contenant un premier port, un deuxième port et un troisième port, le premier port étant couplé en fonctionnement au premier segment guide d'onde optique (151), un deuxième segment guide d'onde optique (152) couplé en fonctionnement au deuxième port du circulateur optique (104), et une matrice d'éléments de détection (110). Chacun des éléments de détection peut comprendre un détecteur (230) et un modulateur électro-optique, le modulateur électro-optique (220) étant couplé en fonctionnement au deuxième segment guide d'onde optique. L'exemple de système peut comprendre en outre un troisième segment guide d'onde optique (153) couplé en fonctionnement au troisième port du circulateur optique (104), un interféromètre ...

LED LIGHTING AND OF VENTILATION COMBINE

Conduit d'éclairage et de ventilation combinés, comprenant au moins deux tuyaux optiques (110) à l'intérieur desquels de l'air est amené à passer, de la lumière se propageant dans les au moins deux tuyaux optiques (110) en étant totalement réfléchie, et un élément de raccordement (120) raccordant les uns aux autres les au moins deux tuyaux optiques, l'élément de raccordement (120) ayant un embout de raccordement (125) destiné à être raccordé à un tuyau (30). Une partie supérieure du conduit est noyée dans un faux-plafond (20) sous un vrai plafond (10) et une partie inférieure est exposée sous le faux-plafond (20). Selon une autre possibilité, l'ensemble du conduit d'éclairage et de ventilation combinés est installé de manière à être exposé sous le faux-plafond (20). Lorsque l'air et la lumière se propagent dans le conduit d'éclairage et de ventilation combinés, la lumière est totalement réfléchie à l'intérieur des tuyaux optiques (110) afin d'éclairer un espace intérieur et l'air est fourni ...

METHOD OF TREATING WASTE RADIOACTIVE ION EXCHANGE RESINS, AND APPARATUS THEREFOR

La présente invention concerne un procédé et un appareil de traitement de déchets de résines échangeuses d'ions contenant des radionucléides. La présente invention concerne également un procédé de traitement de déchets de résines échangeuses d'ions contenant des radionucléides par un traitement thermique par étapes et un appareil pour mettre en œuvre ledit procédé.

ELASTOMER COMPOUNDS

Il est décrit ici des composés élastomères comprenant : au moins un élastomère qui est résistant à la chaleur pendant 70 h à 100°C de sorte que le au moins un élastomère présente au moins une des propriétés suivantes choisies parmi : (a) une modification de dureté d'après duromètre d'au plus 15 points, (b) une modification de résistance à la traction d'au plus 40 %, et (c) une modification d'allongement à la rupture d'au plus 40 %. Le composé élastomère comprend de plus au moins un matériau à base de graphène présent dans une quantité de 0,01 pcc à 30 pcc par rapport au au moins un élastomère et au moins un noir de carbone présent dans une quantité de 15 pcc à 150 pcc par rapport au au moins un élastomère. Il est également décrit des procédés de fabrication de tels composés, et des articles comprenant des composés élastomères.

Farbzusammensetzung mit selbstständig Kratzer-beseitigenden Eigenschaften

Die Erfindung betrifft eine selbstständig Kratzer-wiederherstellende Farbzusammensetzung, die eine verkürzte Trocknungszeit und eine verlängerte Topfzeit aufweist, und bezogen auf das Gesamtgewicht der Farbzusammensetzung ungefähr 3040 Gew.-% eines verzweigten Polyesterharzes; ungefähr 3040 Gew.-% eines Acryl-Polyol-Harzes; ungefähr 0,20,5 Gew.-% eines Reaktionskatalysators; und ungefähr 0,9909 Gew.-% eines Reaktionsverzögerers enthält.

Arzneimittelzusammensetzung zur Prophylaxe und Behandlung vorzeitigen Samenergusses

PROCESS TO DETECT a CRACK CROSSING the WALL Of a TUBE AND TO MEASURE LALONGUEUR OF the CROSSING CRACK

HEMISPHERICAL RESONATOR GYROSCOPE MILLIMETER WITH INTERNAL FORCE.

Processing method call signaling intelligent network service in an electronic communications system for long distance/a tandem.

PROCESS AND APPARATUS TO REDUCE THE POWER IN MEMORIES HIDING PLACE ETSYSTEME OF DATA PROCESSING COMPRISING OF MEMORIES CHACHES

FIBRE OF POLYETHYLENE NAPHTALATE OF HIGH STRENGTH

ORGANIC TRANSISTOR IN THIN LAYERS, DISPLAY DEVICE HAS LIQUID CRYSTALS USING THIS TRANSISTOR, AND THEIR MANUFACTORING PROCESS

METHOD OF PREPARING A NANOSTRUCTURE RADIOISOTOPE WITH A FRAMEWORK METAL-LIGAND AND APPLICATION THEREOF

DEVICE ELECTROLUMINESCENT AND MANUFACTORING PROCESS OF THIS ONE

Dispositif électroluminescent comprenant un premier substrat (300) et un second substrat (350), chaque substrat étant subdivisé entre une région de contact (A) et une région de pixel (B). Selon l'invention, les éléments conducteurs positionnés dans chacune de la région de contact (A) et de la région de pixel (B) du premier substrat peuvent être sensiblement de la même hauteur, permettant de raccorder la couche de contact du premier substrat à une seconde ligne métallique du second substrat. Application à la fabrication d'un dispositif électroluminescent organique (OLED) dans lequel des transistors à couches minces (TFT) sont d'abord formés sur un substrat, puis des diodes électroluminescentes sont formées sur le transistor à couches minces.

OPTICAL AMPLIFIER HAS WEAK NOISE AND OPTICAL COMMUNICATION SYSTEM USING It

PROCESS Of ENERGY SAVING FOR AIR-CONDITIONER

TRANSMITTER, RECEIVER AND THEIR PROCESS IN A COMMUNICATION SYSTEM WITH THE HUMAN BODY.

Récepteur dans un système de communication avec le corps humain, comprenant des électrodes réceptrices (1 à n) comprenant une trame de transmission comprenant des trames de commande (300) et des trames de données (400), des premier et deuxième commutateurs connectés aux électrodes réceptrices (1 à n), une unité de commande de commutation (250) des premier et deuxième commutateurs (211, 212) pour connecter les électrodes réceptrices (1 à n) aux premier et deuxième commutateurs en réponse à chaque trame de commande (300), une unité de traitement de signal (214) en sortie des premier et deuxième commutateurs, une unité de détection de préambule (230) pour générer des valeurs de corrélation de préambule pour le premier préambule, et une unité de traitement de valeur de corrélation (240) commandant l'unité de commande de commutation (250) pour sélectionner des paires d'électrodes réceptrices (1 à n) finales sur la base des valeurs de corrélation de préambule.

LIGHT GUIDING PANEL AND LIQUID CRYSTAL DISPLAY DEVICE

METHOD OF OXIDE DISPERSION STRENGTHENED METAL MATERIAL USING A LASER

APPARATUS OF AUXILIARY CONDENSATION PASSIVE OF NUCLEAR PLANT

Un appareil de condensation auxiliaire passif d'une centrale nucléaire comprend une unité de génération de vapeur (110) configurée pour chauffer de l'eau (3) qui y est délivrée en une vapeur (5) par une chaleur produite lors du fonctionnement d'un réacteur nucléaire, une unité d'échange de chaleur refroidie par eau (120) reliée à l'unité de génération de vapeur (110) et configurée pour stocker une eau de refroidissement (1) afin de condenser la vapeur (5) délivrée par l'unité de génération de vapeur (110), et un réservoir de séparation vapeur-eau (140) comprenant un côté relié à l'unité d'échange de chaleur refroidie par eau (120) et l'autre côté relié à l'unité de génération de vapeur (110), un mélange d'eau (3) et de vapeur (5) délivré par l'unité d'échange de chaleur refroidie par eau (120) étant séparé en eau (3) et en vapeur (5) afin de délivrer seulement l'eau (3) à l'unité de génération de vapeur (110) .

CONDENSING APPARATUS AUXILIARY PASSIVE NUCLEAR POWER PLANT

DISPLAY DEVICE HAS Touchscreen

MACHINE AND a METHOD FOR GRINDING a GRID Of SPACING Of a UNIT HAVE FUEL NUCLEAR

La présente invention propose une machine et un procédé pour meuler une grille d'espacement d'un ensemble à combustible nucléaire. La machine comprend une unité de support de grille d'espacement, un premier robot à coordonnées rectangulaires pour meuler une surface externe de la grille d'espacement, un deuxième robot à coordonnées rectangulaires pour meuler un coin de la grille d'espacement et une unité de commande. L'unité de support de grille d'espacement comprend un gabarit de support sur lequel la grille d'espacement est installée et maintenue, et une table circulaire rotative qui est couplée au gabarit de support pour faire tourner le gabarit de support. Les premier et deuxième robots à coordonnées rectangulaires sont prévus dans des positions prédéterminées adjacentes à l'unité de support de grille d'espacement. L'unité de commande commande l'unité de support de grille d'espacement, les premier et deuxième robots à coordonnées rectangulaires et tous les programmes nécessaires pour ...

SYSTEM OF FOLLOW-UP IN Real-time Of a FUEL SWIMMING POOL EXHAUSTS AND PROCEEDED FOR THIS ONE

La présente invention se rapporte à un système de surveillance en temps réel d'une piscine de combustible épuisé, le système comportant : une unité de détection (100) configurée pour détecter de l'information de condition ; une unité de stockage d'entrée (200) configurée pour recevoir et stocker l'information de configuration d'un combustible usagé ; une unité d'opération et de détermination (300) configurée pour calculer l'information de condition courante du combustible usagé en utilisant l'information de condition détectée par l'unité de détection (100) et l'information de configuration et l'information d'historique stockées dans l'unité de stockage d'entrée (200) et configurée pour déterminer un niveau de risque en comparant l'information de condition courante à la valeur limite correspondant au niveau de risque ; et une unité d'affichage (400) .

GYROSCOPE HAS HEMISPHERICAL RESONATOR MILLIMETRE-LENGTH HAS INTERNAL DEVICE OF FORCE.

Le gyroscope à résonateur hémisphérique millimétrique à dispositif de force interne (GRHm) est un gyroscope petit, de faible coût et à hautes performances. Il peut présenter une conception extrêmement simplifiée ne comportant, dans un mode de réalisation du présent procédé et du présent appareil, que cinq pièces principales au total, la plupart des pièces remplissant de multiples fonctions. Le procédé et l'appareil dans un mode de réalisation peuvent comporter : un résonateur (108) et un corps (105) couplé fonctionnellement au résonateur, le corps simple comportant de manière intégrée des électrodes, une unité de support d'électrodes (107) , une bague soudée et une pluralité de broches (112) électriquement conductrices, la pluralité d'électrodes étant couplée fonctionnellement aux broches électriquement conductrices.

Verfahren zum Wiederauffinden von Bildtexturen und Vorrichtung dafür

DATENTRÄGERKASSETTE UND DATENTRÄGERLAUFWERKVORRICHTUNG DAMIT

Verfahren und Vorrichtung zum Durchführen von Handover zwischen Kernnetzwerkeinheiten in einem paketvermittelten Netzwerk

Streptococcus pneumoniae-Antigene und Impfstoffe

Herstellung von hochfestem und hochschlagzähem Polypropylen/Nanoton/Kautschuk-Komposit unter Verwendung einer Kautschuk/Nanoton-Vormischung

Offenbart hier sind eine Zusammensetzung aus einer Kautschuk/Nanoton-Vormischung und ein Verfahren zur Herstellung einer hochfesten und hochschlagzähen Zusammensetzung aus einem Polypropylen/Nanoton/Kautschuk-Komposit unter Verwendung der vorstehenden Zusammensetzung. Insbesondere ist ein Verfahren zur Herstellung einer Kautschuk/Nanoton-Vormischung unter Verwendung eines modifizierten Polymers mit einem hohen Gehalt an Maleinsäureanhydrid als Verträglichmacher bereitgestellt. Gemäß dem offenbarten Verfahren wird eine Nanoton-Vormischung auf Kautschukbasis bereitgestellt und diese kann bei Zugabe zu Propylen unter vorteilhafter Verbesserung der Schlagzähigkeit eine durch Kautschukzugabe verursachte Abnahme des Biegemoduls verhindern. Zudem kann unter Verwendung eines mit Maleinsäureanhydrid gepfropft-modifizierten Polymers mit einen hohen Gehalt an Maleinsäureanhydrid eine Zusammensetzung aus einer Kautschuk/Nanoton-Vormischung mit ausgezeichneter Dispergierbarkeit in Polymer erhalten werden ...

INTEGRATED CIRCUIT INCORPORATING A CIRCUIT TO CONTROL TRANSISTORS DEPUISSANCE GO UP ACCORDING TO A CONFIGURATION IN DEMI-PONT ALLOWING AN EXCESSIVE OSCILLATIONNEGATIVE OF THE NODE OF EXIT

METHOD FOR DETERMINING A SPEED LIMIT IN FORCE ON A ROAD TAKEN BY A MOTOR VEHICLE

DRUM TYPE WASHER.

METHOD AND APPARATUS FOR RETRANSMITTING DATA IN A MOBILE COMMUNICATION SYSTEM CDMA

APPARATUS FOR PASSIVE COOLING OF SPENT FUEL POOL

VIBRATOR LINEAR SMT

PROCESS OF POWER CONTROL DURING A TRANSFER WITHOUT CUT IN UNSYSTEME OF MOBILE COMMUNICATION

DRYER HAS VAPOR AND HAS HOT BREATH, AND ITS PROCESS OF ORDER.

PROGRAMMABLE APPARATUS TO DYNAMICALLY CONTROL THE VOLTAGE

La présente invention concerne un appareil programmable de commande dynamique de la tension, et plus particulièrement un appareil programmable de commande dynamique de la tension en mesure de commander dynamiquement la conversion de tension d'une unité de sortie en utilisant des données réglées dans des mémoires programmables, quand divers éléments d'informations détectés par une variété de capteurs montés dans un véhicule sont convertis en signaux électriques puis transmis.

Fabric e.g. clothes, treating e.g. drying, apparatus, has condensed water treating element treating condensed water that is formed under effect of condensation of vaporized humidity in storing space or air supplied by air supplying device

Est divulgué un appareil de traitement des tissus qui fournit de l'air chaud à un espace de logement (110) recevant des vêtements afin de sécher ces derniers. Cet appareil comprend une armoire (100) comprenant un espace de logement (110) pour recevoir des vêtements et une chambre de composants électriques (120) où sont installés un dispositif pourvoyeur d'humidité (140) pour vaporiser de la vapeur d'eau dans l'espace de logement (110) et un dispositif d'alimentation en air (130) pour fournir de l'air chaud ; et un élément de traitement de l'eau condensée pour traiter l'eau condensée formée par la condensation de la vapeur d'eau vaporisée dans l'espace de logement (110) ou de l'air chaud fourni par le dispositif d'alimentation en air (130). Par conséquent, cet appareil traite l'eau condensée formée dans l'espace (110) et empêche ainsi la formation de substances nocives pour l'organisme humain, comme la moisissure, dans cet espace (110).

Cloth treating e.g. refreshing, apparatus, has noise preventing device installed at level of inlet opening for avoiding noise generated inside equipment chamber and outside equipment chamber

Un appareil de traitement de vêtements (100) traitant des vêtements dans un état approprié pour être portés est décrit et comprend une armoire (101), un espace de réception (110) défini dans l'armoire pour recevoir des vêtements, des dispositifs de distribution d'air et d'humidité (130, 140) pour distribuer de l'air sec et de l'humidité dans l'espace de réception (110), respectivement, une chambre d'équipement (120) définie dans l'armoire (101) pour recevoir les dispositifs de distribution d'air chaud et de vapeur, la chambre d'équipement (120) comprenant un orifice d'admission (121) pour laisser l'air extérieur s'introduire dans la chambre d'équipement (120) à travers celui-ci pour refroidir les dispositifs de distribution d'air chaud et de vapeur, et un dispositif de prévention du bruit installé au niveau de l'orifice d'admission (121) pour empêcher le bruit généré dans la chambre d'équipement (120) d'être émis en dehors de la chambre d'équipement (120) à travers l'orifice d'admission ...

ROBOT Of INSPECTION OF the TYPE HAS TIGHTENING OF FINGERS FOR the TUBES Of a STEAM GENERATOR

Le robot d'inspection (R) comprend un module à déplacement avant ou arrière (10), un module à déplacement gauche ou droite (20), espacé du module à déplacement avant ou arrière (10), un module à dispositif d'inspection (30) installé sur le module à déplacement avant ou arrière (10) pour examiner l'intérieur de tubes de chauffe, et des modules de serrage (40) installés avec possibilité de déplacement vertical et horizontal et de rotation et comprenant une pluralité d'éléments de serrage à doigt, destinés à être insérés dans les tubes de chauffe par un mouvement vertical, de manière à serrer simultanément les tubes de chauffe. Grâce au déplacement avant ou arrière, au déplacement gauche ou droite et à la rotation des modules de serrage (40), le robot d'inspection (R) peut être déplacé librement pour examiner les tubes de chauffe, situés à différents emplacement, et peut serrer facilement les tubes de chauffe, ce qui permet d'obtenir un temps d'inspection réduit et une inspection stable.

Mobile terminal e.g. folding type mobile phone, for displaying broadcasted image, has control unit for controlling image such that image is displayed on screen-saver, and display for displaying image under control of control unit

Terminal mobile (100) comprenant un module de réception de diffusion (111) pour recevoir une image diffusée, une unité de commande (180) pour commander l'image diffusée de façon qu'elle soit affichée sur un écran de veille conformément à des informations d'affichage préétablies de l'écran de veille, et un afficheur (151) pour afficher l'image diffusée sous le contrôle de l'unité de commande (180). Puisqu'une image diffusée est affichée sur l'écran de veille, l'utilisateur peut y trouver du plaisir et de l'intérêt.

SYSTEM OF VENTILATION/ECLAIRAGE AND METHOD OF CORRESPONDING ORDER

Une conduite de ventilation/éclairage est décrite qui peut non seulement ventiler un espace intérieur, mais également peut éclairer l'espace intérieur. Un système de ventilation/éclairage utilisant la conduite de ventilation/éclairage et un procédé de commande pour le système de ventilation/éclairage sont également décrits. Le système de ventilation/éclairage comprend un dispositif de ventilation destiné à souffler de l'air, un dispositif d'alimentation en lumière destiné à fournir une lumière, une conduite de ventilation/éclairage destinée non seulement à guider l'air soufflé par le dispositif de ventilation pour ventiler un espace intérieur, mais également à réfléchir totalement la lumière pour éclairer un espace intérieur et un épurateur agencé dans la conduite de ventilation/éclairage.

PROCESSES AND CIRCUITS Of INPUT/OUTPUT OF DATA WHICH REVERSE LESBITS SELECTIVELY

IMAGE PROCESSING DEVICE, LEVELING DEVICE, DISPLAY SYSTEM INCLUDING THE SAME, AND CONTROL METHOD THEREOF

MACHINE HAS LINEN HAVING a VAPOR FEEDING ATTACHMENT

DISPLAY DEVICE

CARBON BLACK WITH AN STSA OF 80 TO 150 M2/G, AN OAN OF AT LEAST 180 ML/100G AND A COAN OF AT LEAST 110 ML/100G AND RUBBER COMPOUNDS INCORPORATING SAME

La présente invention concerne des noirs de carbone tels que des noirs de carbone de qualité renforcement hautement structurés. Le noir de carbone peut avoir les propriétés suivantes : une surface par épaisseur statistique (STSA) comprise entre 80 m2/g et 150 m2/g, un indice d'absorption d'huile (OAN) d'au moins 180 mL/100 g, et un indice d'absorption d'huile d'échantillons comprimés (COAN) d'au moins 110 mL/100 g. Elle concerne également des mélanges de caoutchouc qui incorporent le noir de carbone.

WEARABLE TERMINAL

L'invention concerne un terminal portable (100) comportant un corps principal (101), une carte principale (185) dans le corps principal (101), un premier pavé tactile (200) sur une surface arrière du corps principal (101), une carte flexible configurée pour connecter le corps principal (101) au premier pavé tactile (200), un bracelet (102) couplé au corps principal (101), enroulé autour d'un poignet d'un utilisateur pour immobiliser le corps principal (101) à la partie corporelle de l'utilisateur, un deuxième pavé tactile (210) sur l'autre surface d'une surface en contact avec la partie corporelle de l'utilisateur lorsque l'utilisateur porte le bracelet (102), une carte flexible ayant une extrémité connectée au deuxième pavé tactile (210) et l'autre à la carte principale (185), et un contrôleur (180) configuré pour extraire un électrocardiogramme par une mesure d'une différence de potentiels électriques de muscles corporels détectés par le premier pavé tactile (200) et le deuxième pavé ...

Mobile terminal i.e. mobile telephone, for use in mobile communication system to provide mobile communication system to e.g. local landowner, has middleware module transmitting processing result of mobile secured module function

Il est proposé un procédé et un dispositif pour fournir une fonction de module sécurisé mobile. En essayant d'effectuer une fonction de module sécurisé mobile pendant l'exécution d'une application sécurisée, un terminal mobile (100) génère une instruction correspondant à une fonction de module sécurisé mobile à effectuer, la transmet à un module d'identité universelle d'abonné (200), et acquiert un résultat de traitement d'une fonction de module sécurisé mobile sur la base d'un résultat de traitement d'une instruction de module sécurisé mobile correspondante reçue d'un module d'identité universelle d'abonné (200).

PORTE-SONDE FOR SENSOR OF ENGINE HAS TURBINE

Turbine (10) comprenant un organe ayant un corps, lequel peut tourner autour d'un axe géométrique central (122) d'un rotor et lequel est formé de manière à définir une cavité radialement très proche d'un point de mesure concerné (20) défini à une certaine distance radiale de l'axe géométrique central (122), un capteur (25) servant à mesurer un état au point de mesure concerné (20), un système de communication (30) par lequel des mesures d'états sont transmissibles du capteur (25) à un système d'enregistrement non rotatif et un porte-sonde insérable dans la cavité afin d'immobiliser le capteur (25) tout près du point de mesure concerné (20).

APPARATUS OF PASSIVE COOLING OF FUEL SWIMMING POOL EXHAUSTS

Un appareil destiné à refroidir une piscine de combustible épuisé (100) ayant un échangeur de chaleur (20) comprend une piscine d'eau de refroidissement (200) positionnée au-dessus de la piscine de combustible épuisé (100) ; un dispositif flottant (320) configuré pour être élevé en fonction d'un niveau d'eau d'une eau de refroidissement (110) dans la piscine de combustible épuisé (100) ; et un tuyau d'alimentation en eau de refroidissement de secours (300) configuré pour former un passage par l'intermédiaire duquel l'eau de refroidissement (110) de la piscine d'eau de refroidissement (200) est déplacée vers la piscine de combustible épuisé (100) et configuré pour comprendre une soupape à flotteur (310) qui ouvre ou ferme un passage d'écoulement de l'eau de refroidissement (110) en liaison avec la hauteur du dispositif flottant (320).

MACHINE AND METHOD FOR GRINDING A SPACER GRID OF A NUCLEAR FUEL ASSEMBLY

MANUFACTORING PROCESS Of a CELL Liquid crystal HAS

TOGETHER OF GRID FOR APPARATUS OF COLLECTION OF DUST HAS CYCLONE POURASPIRATEUR AND VACUUM CLEANER EQUIPS With SUCH a UNIT

SAFETY INJECTION SYSTEM USING A PASSIVE SAFETY INJECTION TANK

Curved display device e.g. LCD device, has a display screen having different curvatures with different radius of curvature that corresponds to radius of a circular arc which intersects with the corresponding segment of display screen

Un dispositif d'affichage (100) est fourni. Le dispositif d'affichage (100) inclut un écran d'affichage (DP1) destiné à afficher des images, et l'écran d'affichage (DP1) inclut différentes courbures au niveau de différents segments (HR1, HR2, HR3) de l'écran, chacune des différentes courbures présentant un rayon de courbure distinct, chaque rayon de courbure correspondant à un rayon d'un arc de cercle qui se rapproche d'une courbe croisant le segment correspondant (HR1, HR2, HR3).

DETERMINATION OF THE QUALITY OF RECEPTION IN A DEVICE OF RADIO COMMUNICATION.

Dispositif de communication radio, comprenant : un récepteur (202) configuré pour recevoir des signaux radio ; un circuit (204) de mesure configuré pour mesurer la qualité de réception de signaux radio reçus ; et une unité (206) de commande configurée pour commander le circuit (204) de mesure de façon à ce qu'une première mesure soit effectuée en utilisant la première largeur de bande de fréquences déterminée pour ainsi déterminer une première qualité de réception.

COMPOSITION OF RESERVE CHEMICALLY AMPLIFIEE CONTAINING OF SILICON

MOBILE TERMINAL AND METHOD FOR DISPLAYING SCREEN SAVER THEREOF

ZIRCONIUM ALLOY FOR IMPROVING OXIDATION RESISTANCE AT A VERY HIGH TEMPERATURE AND ITS MANUFACTURING METHOD.

APPARATUS INTENDS TO CHARGE A SPARE BATTERY BY USING A THERMOELECTRIC DEVICE OF GENERATION IN THE NUCLEAR PLANT

La présente invention se rapporte à un appareil destiné à charger une batterie de secours (300), qui délivre une alimentation de secours à un appareil de refroidissement de cœur de secours comprenant une pompe électrique ou une pompe à vapeur, l'appareil comportant : un dispositif de génération thermoélectrique (100) configuré pour détecter une chaleur de désintégration et une chaleur résiduelle produites dans une centrale nucléaire et configurée pour convertir la chaleur détectée en énergie électrique ; une unité de conversion d'énergie électrique (200) reliée au dispositif de génération thermoélectrique (100) pour sortir un courant généré dans le dispositif de génération thermoélectrique (100) sous forme d'une tension constante ; et la batterie de secours (300) configurée pour stocker une puissance délivrée par l'unité de conversion d'énergie électrique (200).

MOBILE COMMUNICATION NETWORK AND OF VIDEODIFFUSION WAITER AND PROCEDED' EXPLOITATION

Dans un système de communication comportant un réseau (201) de communication par radiodiffusion et un réseau (202) de communication par téléphonie mobile, des ressources radioélectriques sont affectées à l'utilisateur d'un terminal (204) de téléphonie mobile en tenant compte d'une priorité d'utilisateur de la radiodiffusion de l'utilisateur.

TRANSMITTER, RECEIVER AND THEIR PROCESS IN A COMMUNICATION SYSTEM WITH THE HUMAN BODY

Récepteur dans un système de communication avec le corps humain, comprenant des électrodes réceptrices (1 à n) comprenant une trame de transmission comprenant des trames de commande (300) et des trames de données (400), des premier et deuxième commutateurs connectés aux électrodes réceptrices (1 à n), une unité de commande de commutation (250) des premier et deuxième commutateurs (211, 212) pour connecter les électrodes réceptrices (1 à n) aux premier et deuxième commutateurs en réponse à chaque trame de commande (300), une unité de traitement de signal (214) en sortie des premier et deuxième commutateurs, une unité de détection de préambule (230) pour générer des valeurs de corrélation de préambule pour le premier préambule, et une unité de traitement de valeur de corrélation (240) commandant l'unité de commande de commutation (250) pour sélectionner des paires d'électrodes réceptrices (1 à n) finales sur la base des valeurs de corrélation de préambule.

FRAME OF LID FOR CONTAINER OF TRANSPORT Of ASSEMBLY OF FUEL NUCLEAR AND CONTAINER OF TRANSPORT FOR NUCLEAR FUEL ASSEMBLIES

Un bâti de couvercle pour un conteneur de transport d'assemblage de combustible nucléaire (10) et un conteneur de transport pour des assemblages de combustible nucléaire sont prévus. Le conteneur de transport comprend un conteneur inférieur (100) dans lequel un berceau (130) est installé, un conteneur supérieur (200) relié de manière démontable au conteneur inférieur (100), et un bâti de base (300) relié au berceau (130) avec au moins un assemblage de combustible nucléaire (10) placé dessus, et le bâti de couvercle (400) comprend une pluralité de supports (410) installés à l'écart l'un de l'autre de façon à entourer l'assemblage de combustible nucléaire placé sur le bâti de base, une pluralité de brides (420) séparées l'une de l'autre, reliées aux supports de façon à être perpendiculaires aux supports, articulées de manière rotative sur le bâti de base, et serrant l'assemblage de combustible nucléaire, et une pluralité de compensateurs d'espace reliés aux surfaces intérieures des supports ...

SUPPORT FRAME AND DISPLAY DEVICE INCLUDING THE ABOVEMENTIONED

Schwarzes, pastenförmiges Verbundmaterial, obere Platte einer Plasmaanzeigetafel und Herstellungsverfahren unter Verwendung desselben

Führungsstift-Basis-Vorrichtung

BIPOLAR BATTERY

MULTI-LAYER CERAMICS SUBSTRATE AND MANUFACTORING PROCESS OF THIS ONE

TRANSMITTER, RECEIVER AND METHOD IN A COMMUNICATION SYSTEM WITH THE HUMAN BODY

DISPLAY DEVICE TO SEIZE the CHARACTERS OF THE AFORESAID DEVICE

La présente invention concerne un dispositif d'affichage permettant de saisir les caractères dudit dispositif. Le dispositif d'affichage comprend : une unité d'affichage qui affiche une interface utilisateur de saisie de caractères comprenant une pluralité d'objets caractères, chaque objet caractère comprenant une bordure et un caractère situé dans la bordure, une unité de saisie qui reçoit une commande utilisateur pour la sélection de l'un de la pluralité d'objets caractères, et un dispositif de commande qui, si un premier objet caractère est sélectionné parmi la pluralité d'objets caractères au travers de l'unité de saisie, commande à l'unité d'affichage d'afficher au moins un objet caractère de recommandation associé au premier caractère en chevauchement partiel avec les objets caractères adjacents au premier objet caractère. Ainsi, un utilisateur peut saisir des caractères plus facilement au moyen de l'interface utilisateur de saisie de caractères.

TUBE PLATE OF A STEAM GENERATOR HAVING A CORROSION-RESISTANT LAYER AND MANUFACTURING METHOD THEREOF

La présente invention concerne une plaque tubulaire d'un générateur de vapeur installée pour supporter un tube du générateur de vapeur et un procédé de fabrication de celle-ci , notamment une plaque tubulaire d'un générateur de vapeur ayant une couche anticorrosive et un procédé de fabrication de celle-ci.

PROCESS AND CIRCUIT Of ADJUSTMENT OF CONTRAST IN a DISPLAY DEVICE

EARTHQUAKE RESISTANT LID FOR CONTAINER TRANSPORTATION OF NUCLEAR FUEL ASSEMBLY AND SHIPPING CONTAINER FOR NUCLEAR FUEL ASSEMBLIES

LIQUID LENS HAS FOCAL VARIABLE WITH TENSION OF REDUCED ORDER

PROCESS AND APPARATUS TO TRANSMIT INFORMATION OF SETS OF CONTROL CHANNELS DIVISIONS IN A MOBILE SYSTEM OF TELECOMMUNICATION ALLOWING THE DATA TRANSMISSION IN MODE OF PACKAGES

ORGANIZES HOLLOW LETTERS HAS PROGRESSIVE RESTITUTION AND ITS PROCESSES OF CREATION, TRANSMISSION AND RESTITUTION

AN APPARATUS FOR TISSUE TREATMENT.

PROCESSOR OF CLOTHING.

.

METHODS FOR TREATING CANCER AND NON-NEOPLASTIC CONDITIONS

Compounds that selectively inhibit pathological production of human vascular endothelial growth factor (VEGF) and compositions comprising such Compounds are described. Compounds that inhibit viral replication or the production of viral RNA or DNA or viral protein and compositions comprising such Compounds are described. Also described are methods of reducing VEGF using such Compounds and methods for treating cancer and non-neoplastic conditions involving the administration of such Compounds. Further described are methods of inhibiting viral replication or the production of viral RNA or DNA or viral protein using such Compounds and methods for treating viral infections involving the administration of such Compounds. The Compounds may be administered as a single agent therapy or in combination with one or more additional therapies to a human in need of such treatments. 2. A pharmaceutical composition comprising the compound of .5. The method of claim 3 , wherein the cell is in a subject.6. The method of claim 4 , wherein in the cell is in a subject.13. A method for treating cancer in a human in need thereof claim 1 , comprising administering to the human an effective amount of the compound of .14. A method for treating a non-neoplastic condition in a human in need thereof claim 1 , comprising administering to the human an effective amount of the compound of .15. A method for treating a viral infection in a human in need thereof claim 1 , comprising administering to the human an effective amount of the compound of .16. The method of claim 13 , wherein the cancer is a solid tumor cancer.17. (canceled)18. The method of claim 14 , wherein the non-neoplastic condition is rheumatoid arthritis claim 14 , obesity claim 14 , psoriasis claim 14 , atherosclerosis claim 14 , diabetic retinopathy claim 14 , retinopathy of prematurity claim 14 , retrolental fibroplasia claim 14 , neovascular glaucoma claim 14 , age-related macular degeneration claim 14 , exudative macular ...

SURGICAL DRILL GUIDE ADAPTER WITH A HANDLE AND DETACHABLE HEAD

A dental implant surgical guide system is disclosed. A surgical guide is placed onto a patient's mouth. The surgical guide has one or more tubes for accepting detachable drill guide heads. The detachable drill guide heads are placed into a tube of the surgical guide using a handle. The handle has an attach/detach mechanism. A first drill guide head having a first inner diameter is attached to the handle to guide drilling of a first hole. The first drill guide head is removed using the attach/detach mechanism to accept a second drill guide head having a second inner diameter to guide drilling of a second hole. 1. A surgical guide system comprising:a surgical guide adapted to be placed onto a patient's mouth, the surgical guide having one or more tubes;a first drill guide head having a first inner diameter;a second drill guide head having a second inner diameter; anda handle comprising an attach/detach mechanism,wherein the first drill guide head is attached to the handle, removed from the tube, and detached from the handle using the attach/detach mechanism, andwherein the second drill guide head is attached to the handle and inserted into the tube.2. The surgical guide system of claim 1 , wherein the handle has a profile for clearing obstructions and/or reaching into the back of the patient's mouth.3. The surgical guide system of claim 1 , wherein one of first drill guide head and the second drill guide head is attachable to the handle at at least two different angles.4. The surgical guide system of claim 1 , wherein the attach/detach mechanism provides sufficient torsional rigidity to hold the position of the head while drilling.5. The surgical guide system of claim 1 , wherein the attach/detach mechanism is engaged by a selected from a group comprising a push button switch claim 1 , a slide switch claim 1 , a rocker switch claim 1 , a rotary switch claim 1 , an electrical switch claim 1 , and an electromagnetic switch.6. The surgical guide system of claim 1 , ...

INSECT PROOF AND INSECTICIDAL COMPOSITION FOR THE CONSERVATION OF CULTURAL PROPERTY COMPRISING Asarum sieboldii EXTRACT OR A FRACTION THEREOF AS AN ACTIVE INGREDIENT

Disclosed herein is an insect proof or insecticidal composition for the conservation of cultural properties against termites, comprising an extract of Asarum sieboldii as an active ingredient. Based on a methanol extract of Asarum sieboldii or a hexane fraction from the methanol extract, the composition is environmentally friendly and non-toxic to humans and animals. Also, because of its excellent insecticidal activity against termites, the composition can be used to protect wooden structures and cultural properties from termite damage, which is a great threat to the life of wooden structures and cultural properties, without toxicity to humans and animals.

Method and System for Generating a Dental Implant Surgical Drill Guide

A method and system for producing a dental implant surgical guide is disclosed. A patient-specific virtual model is generated using image data specific to a patient and virtual dental implants. The virtual model aligns the image data with the virtual dental implants using modeling software. A virtual mold is generated from the virtual model, and a physical mold is generated from the virtual mold. The physical mold is covered with a thermoplastic sheet via a thermoforming process. Excess thermoplastic material is trimmed off after the thermoforming process to produce a thermoformed piece. Metal tubes corresponding to each the virtual dental implants are placed onto the physical mold denoting the position, trajectory, and depth of the one or more virtual dental implants. A dental implant surgical guide that contains the thermoformed piece with the one or more tubes is produced. 1. A method for producing a dental implant surgical guide , the method comprising:receiving image data specific to a patient;determining position, trajectory and depth of one or more virtual dental implants;generating a virtual model based on the one or more virtual dental implants, wherein the virtual model aligns the image data with the one or more virtual dental implants;generating a virtual mold based on the virtual model;generating a physical mold from the virtual mold;covering the physical mold with a thermoplastic sheet via a thermoforming process;trimming off excess thermoplastic material after the thermoforming process to produce a thermoformed piece;placing one or more tubes corresponding to each one or more virtual dental implants onto the physical mold, wherein the one or more tube denote the position, trajectory, and depth of the one or more virtual dental implants; andproducing a dental implant surgical guide that contains the thermoformed piece with the one or more tubes.2. The method of claim 1 , wherein the image data provides sufficient resolution claim 1 , image detail claim ...

Indoor artificial breeding method of termite

Provided is a method of collecting wild termites and rearing the termites indoors. The method can be used to observe physiological and ecological characteristics of termites that give serious damage to wooden cultural assets and buildings, and thus basic information can be obtained for controlling termites.

Patient-Specific Three-Dimensional Dentition model

A method and system for generating a color-textured three-dimensional dental model is specific to a patient is disclosed. According to one embodiment, a three-dimensional dental model that is deficient of volumetric data for a three-dimensional anatomical landmark is obtained. A two-dimensional anatomical landmark of a two-dimensional intra-oral photograph that corresponds to the three-dimensional anatomical landmark of the three-dimensional dental model is identified. The two-dimensional intra-oral photograph is projected onto the three-dimensional dental model. The three-dimensional anatomical landmark is calculated from the projection of the two-dimensional anatomical landmark of the two-dimensional intra-oral photograph. 1. A computer-implemented method comprising:identifying a three-dimensional anatomical landmark of a three-dimensional dental model, the three-dimensional anatomical landmark being deficient of volumetric data;identifying a two-dimensional anatomical landmark of a two-dimensional intra-oral photograph that corresponds to the three-dimensional anatomical landmark of the three-dimensional dental model;projecting the two-dimensional intra-oral photograph onto the three-dimensional dental model; andcalculating the three-dimensional anatomical landmark from the projection of the two-dimensional anatomical landmark of the two-dimensional intra-oral photograph.2. The computer-implemented method of further comprising generating a patient-specific color-textured three-dimensional dental model comprising the three-dimensional anatomical landmark.3. The computer-implemented method of claim L wherein the two-dimensional intra-oral photograph is projected onto the three-dimensional dental model using a common anatomical landmark that has volumetric data.4. The computer-implemented method of claim 3 , wherein the common anatomical landmark is selected from a group comprising tips of the teeth claim 3 , interproximal points claim 3 , and gingival margins.5. ...

Apparatus For Generating Volumetric Image and Matching Color Textured External Surface

Embodiments of the invention provide systems and methods for generating combined image data representing a volumetric image of a subject and a color textured external surface of the subject. According to one embodiment, two-dimensional image data and volumetric data of a subject is obtained using it two-dimensional imager and a volumetric scanner, respectively. The two-dimensional image data represent color texture of the subject, and the volumetric data represents both an internal and external structure of the subject. An opacity threshold of the volumetric data is set to render an external surface of the subject without generating external surface mesh data. An array ray is extended from a view point of the two-dimensional image data to the external surface of the subject such that the external surface of the subject has an opacity level higher than the opacity threshold. The two-dimensional image data is mapped to the external surface of the subject based on the extended array ray, and combined image data comprising the two-dimensional image data and the volumetric data is generated. 1. A method comprising:obtaining two-dimensional image data of a surface of the subject using a two-dimensional imager;obtaining volumetric data representing both an internal and external structure of the subject using a volumetric scanner;setting an opacity threshold of the volumetric data to render an external surface of the subject without generating external surface mesh data;extending an array ray from a view point of the two-dimensional image data to the external surface of the subject, wherein the external surface of the subject has an opacity level higher than the opacity threshold;mapping the two-dimensional image data to the external surface of the subject based on the extended array ray; andgenerating combined image data comprising the two-dimensional image data and the volumetric data.2. The method of further comprising visualizing the external surface of the volumetric ...

NOVEL DIPHENYLMETHANE DERIVATIVES AS SGLT2 INHIBITORS

The present invention relates to a compound with a diphenylmethane moiety having an inhibitory activity against sodium-dependent glucose cotransporter 2 (SGLT2) being present in the intestine and kidney, and a pharmaceutical composition comprising the same as an active ingredient, which is useful for preventing or treating metabolic disorders, particularly diabetes. The present invention also provides a method for preparing the compound, and a method for preventing or treating metabolic disorders, particularly diabetes, by using the compound. 5. The compound of , wherein said ring A is a benzene , indane , indene , dihydrobenzofuran , dihydroisobenzofuran , benzofuran , dihydrobenzothiophene , benzothiophene , tetrahydronaphthalene , dihydronaphthalene , chroman , chromene , isochroman , isochromene , benzodioxole , benzodioxane , benzooxazine , tetrahydroquinoline , tetrahydroquinoxaline , tetrahydroisoquinoline , indazole , indole , indoline , benzoimidazole , benzooxazole , benzothiazole , benzotriazole , quinazoline , quinoxaline , cinnoline , phthalazine , or benzotriazine ring , which is optionally substituted with a substituent as defined in .6. The compound of , wherein said ring B is a quinoline , quinoxaline , 3 ,4-dihydro-2H-benzo[b][1 ,4]dioxepine , 2 ,3-dihydrobenzo[b]thiophene , indazole , indole , 2 ,3-dihydrobenzo[b][1 ,4]dioxine , benzodioxole , indane , tetrahydronaphthalene , 3 ,4-dihydro-2H-thiochromene , dihydrobenzofuran , benzo[d][1 ,3]oxathiole , tetrahydroquinoline , or 3 ,4-dihydro-2H-benzo[b][1 ,4]oxazine ring , which is optionally substituted with a substituent as defined in .7. The compound of claim 1 , which is selected from the group consisting of:(1) (2S,3R,4R,5S,6R)-2-(7-bromo-6-(4-methoxybenzyl)-2,3-dihydro-1H-inden-4-yl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol;(2) (2S,3R,4R,5S,6R)-2-(7-bromo-6-(4-ethoxybenzyl)-2,3-dihydro-1H-inden-4-yl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol;(3) (2S,3R,4R,5S,6R)-2-(7-bromo-6-(4- ...

UPPER LIMB REHABILITATION ROBOT

There is provided an upper limb rehabilitation robot including: a base frame that has a side to which a connecting support is rotatably laterally connected; a connecting shaft unit that is rotatably disposed at a side of the connecting support; a link unit that has a side coupled to the connecting shaft unit and the other side with an upper limb connector mounted to enable a person who needs rehabilitation to connect an upper limb; an active actuator that rotates a connecting shaft unit; and a manual actuator that generates resistant torque against rotation to the connecting shaft unit. 1. An upper limb rehabilitation robot comprising:a base frame that has a side to which a connecting support is rotatably laterally connected;a connecting shaft unit that is rotatably disposed at a side of the connecting support;a link unit that has a side coupled to the connecting shaft unit and the other side with an upper limb connector mounted to enable a person who needs rehabilitation to connect an upper limb;an active actuator that is disposed at a side of the connecting support, connected with the connecting shaft unit, and rotates the connecting shaft unit; anda manual actuator that is connected to the connecting shaft unit and generates resistant torque against rotation of the connecting shaft unit.2. The upper limp rehabilitation robot of claim 1 , wherein the connecting shaft unit includes:a shaft body that has a rod shape and is rotatably longitudinally disposed on the connecting support; androtary connecting members that are coupled to a side of the shaft body, connected with the active actuator, and receive torque from the active actuator.3. The upper limp rehabilitation robot of claim 1 , wherein the link unit includes:a first rod fixed to the connecting shaft unit;a second rod with an end rotatably coupled to the connecting shaft unit;a third rod with a side rotatably coupled to the other side of the first rod by a pin; anda fourth rod with both ends rotatably coupled ...

Laser patterning apparatus for three-dimensional object

A laser patterning apparatus for a three-dimensional object includes a laser generator, a beam expander configured to adjust a size of a laser beam generated by the laser generator, a dynamic focusing module configured to adjust a z-axis focus position of the laser beam passing through the beam expander, a scan head configured to adjust x- and y-axis focus position of the laser beam passing through the beam expander, a shape recognizer configured to recognize a shape of a three-dimensional object, and a controller configured to extract x-, y-, and z-axis data of the three-dimensional object and to control the scan head and the dynamic focusing module, in order to pattern the three-dimensional object with the laser beam.

POLYMOROPHS OF 5-AZA-4'-THIO-2'-DEOXYCYTIDINE

The present disclosure provides crystalline polymorphs of 5-aza-4′-thio-2′-deoxycytidine. The crystalline polymorphs may be formulated in a pharmaceutical composition, optionally in combination with an additional chemotherapeutic agent. The crystalline polymorphs are useful to treat various diseases including blood cancers, such as myelodysplastic syndrome and leukemia. A process for preparing the crystalline polymorphs of 5-aza-4′-thio-2′-deoxycytidine is also disclosed. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. 1. A crystalline polymorph of 5-aza-4′-thio-2′-deoxycytidine , wherein the crystalline polymorph has a powder X-ray diffraction pattern that contains peaks at about 8° , about 13° , about 15° , about 17° , about 19° , about 22° , about 23° about 26° , about 28° , about 29° , about 31° , about 33° , and about 37° 2θ.2. The crystalline polymorph of claim 1 , wherein the crystalline polymorph has an X-ray powder diffraction pattern that is substantially similar to claim 1 , or the same as claim 1 , the X-ray powder diffraction pattern shown in .3. A pharmaceutical composition comprising an effective amount of the crystalline polymorph of and a pharmaceutically acceptable carrier.4. The pharmaceutical composition of claim 3 , wherein the composition does not comprise other crystalline polymorphs of 5-aza-4′-thio-2′-deoxycytidine.5. The pharmaceutical composition of claim 3 , wherein the effective amount is of from about 35 mg/mto about 70 mg/m.6. An 5-aza-4′-thio-2′-deoxycytidine compound consisting of the crystalline polymorph of .7. A crystalline polymorph of 5-aza-4′-thio-2′-deoxycytidine claim 1 , wherein the crystalline polymorph has a powder X-ray diffraction pattern that contains peaks at about 6° claim 1 , about 12° claim 1 , about 13° claim 1 , about 14° claim 1 , about 16° claim 1 , about 18° claim 1 , about 20° claim 1 , about 21° claim 1 , ...

DISPLAY APPARATUS

A display apparatus is disclosed. The display apparatus includes: at least one LED display unit including a plurality of LED display panels outputting image lights; a light guide unit including a plurality of in-coupling zones where the image lights are received and a single out-coupling zone to which the received image lights are guided; a plurality of in-coupling holographic optical elements (HOEs) arranged in the in-coupling zones to define the propagation path of the image lights through the light guide unit; and a plurality of out-coupling HOEs arranged in the out-coupling zone to define a path through which the image lights guided through the light guide unit are sent outside the light guide unit. 1. A display apparatus comprising:at least one light emitting diode (LED) display unit comprising a plurality of LED display panels outputting image lights;a light guide unit comprising a plurality of in-coupling zones where the image lights are received and a single out-coupling zone to which the received image lights are guided;a plurality of in-coupling holographic optical elements (HOEs) arranged in the in-coupling zones to define a propagation path of the image lights through the light guide unit; anda plurality of out-coupling HOEs arranged in the out-coupling zone to define a path through which the image lights guided through the light guide unit are sent outside the light guide unit.2. The display apparatus according to claim 1 , wherein the plurality of LED display panels comprise a first LED display panel including a plurality of two-dimensionally arrayed first LED cells to output a first wavelength image light claim 1 , a second LED display panel including a plurality of two-dimensionally arrayed second LED cells to output a second wavelength image light claim 1 , and a third LED display panel including a plurality of two-dimensionally arrayed third LED cells to output a third wavelength image light.3. The display apparatus according to claim 2 , wherein ...

MICRO-LED ARRAY DISPLAY DEVICES

Micro-LED array display devices are disclosed. One of the micro-LED display devices includes: a micro-LED panel including a plurality of micro-LED pixels; a CMOS backplane including a plurality of CMOS cells corresponding to the micro-LED pixels to individually drive the micro-LED pixels; and bumps electrically connecting the micro-LED pixels to the corresponding CMOS cells in a state in which the micro-LED pixels are arranged to face the CMOS cells. The micro-LED pixels are flip-chip bonded to the corresponding CMOS cells formed on the CMOS backplane through the bumps so that the micro-LED pixels are individually controlled. 1. A micro-LED array display device comprising:a micro-LED panel comprising a plurality of micro-LED pixels;a CMOS backplane comprising a plurality of CMOS cells corresponding to the micro-LED pixels; andbumps electrically connecting the micro-LED pixels to the corresponding CMOS cells in a state in which the micro-LED pixels are arranged to face the CMOS cells,wherein the micro-LED pixels have a vertical structure comprising a first conductivity-type semiconductor layer, an active layer, and a second conductivity-type semiconductor layer in this order on a substrate,wherein the active layer and the second conductivity-type semiconductor layer are removed from exposed portions of the first conductivity-type semiconductor layer where none of the micro-LED pixels on the substrate is formed,wherein a first conductivity-type metal layer is formed over the extended portions of the first conductivity-type semiconductor layer where none of the micro-LED pixels is formed and is spaced apart from the micro-LED pixels,wherein the first conductivity-type metal layer functions as a common electrode of the micro-LED pixels, andwherein the micro-LED pixels are flip-chip bonded to the corresponding CMOS cells formed on the CMOS backplane through the bumps so that the micro-LED pixels are individually controlled.2. The micro-LED array display device according ...

PATIENT-SPECIFIC THREE-DIMENSIONAL DENTITION MODEL

A method and system for generating a color-textured three-dimensional dental model is specific to a patient is disclosed. According to one embodiment, a three-dimensional dental model that is deficient of volumetric data for a three-dimensional anatomical landmark is obtained. A two-dimensional anatomical landmark of a two-dimensional intra-oral photograph that corresponds to the three-dimensional anatomical landmark of the three-dimensional dental model is identified. The two-dimensional intra-oral photograph is projected onto the three-dimensional dental model. The three-dimensional anatomical landmark is calculated from the projection of the two-dimensional anatomical landmark of the two-dimensional intra-oral photograph. 1. A computer-implemented method comprising:receiving a three-dimensional dental model including three-dimensional volumetric data specific to a patient;receiving a plurality of two-dimensional intra-oral photographs specific to the patient;identifying a plurality of three-dimensional anatomical landmarks of the three-dimensional volumetric data;identifying a plurality of two-dimensional anatomical landmarks of the plurality of two-dimensional intra-oral photographs that correspond to the plurality of three-dimensional anatomical landmarks;projecting the plurality of two-dimensional intra-oral photographs onto the three-dimensional dental model based on the plurality of two-dimensional anatomical landmarks that correspond to the plurality of three-dimensional anatomical landmarks; andgenerating a patient-specific three-dimensional dental model including the three-dimensional volumetric data and the plurality of two-dimensional intra-oral photographs.2. The computer-implemented method of claim 1 , further comprising:dividing the three-dimensional dental model into a plurality of sections; andprojecting the plurality of two-dimensional intra-oral photographs onto the plurality of sections of the three-dimensional dental model.3. The computer- ...

FIRE SUPPRESSION SYSTEM

A drone-based fire suppression system is disclosed. According to one embodiment, the system includes: an unloader configured to detach a detachable part from a drone; a charging station configured to charge fire suppressant to the detachable part of the drone; and a loader configured to attach the detachable part that is charged by the charging station to the drone. 1. A system comprising:an unloader configured to detach a detachable part from a drone;a charging station configured to charge fire suppressant to the detachable part of the drone; anda loader configured to attach the detachable part that is charged by the charging station to the drone.2. The system of further comprises a landing pad claim 1 ,wherein the landing pad comprises an unloading zone and a loading zone,wherein the unloader detaches the detachable part from the drone in the unloading zone, andwherein the loader attaches the detachable part to the drone in the loading zone.3. The system of claim 2 , wherein the landing pad includes one or more landing strips claim 2 , and wherein a landing strip of the one or more landing strips includes a landing zone in which the drone lands claim 2 , the unloading zone claim 2 , the loading zone claim 2 , and a take-off zone in which the drone takes off from the landing pad.4. The system of further comprises a transport mechanism that is configured to sequentially transport the drone in an order of the landing zone claim 3 , through the unloading zone and the loading zone claim 3 , and to the take-off zone.5. The system of claim 1 , wherein the unloader lowers the detachable part after detaching the detachable part from the drone and detaches a battery pack from the detachable part.6. The system of claim 5 , wherein the charging station attaches a charged battery pack to the detachable part.7. The system of claim 6 , wherein the loader raises the detachable part and attaches the detachable part that is charged with the fire suppressant and the charged battery ...

NEGATIVE ELECTRODE ACTIVE MATERIAL, NEGATIVE ELECTRODE INCLUDING THE NEGATIVE ELECTRODE ACTIVE MATERIAL, SECONDARY BATTERY INCLUDING THE NEGATIVE ELECTRODE, AND METHOD OF PREPARING THE NEGATIVE ELECTRODE ACTIVE MATERIAL

A negative electrode active material as well as a method of preparing a negative electrode active material which includes preparing a silicon-based compound including SiO, wherein 0.5 Подробнее

Energy transfer structure and energy conversion device

An energy transfer structure includes an energy transfer material and a vacant space part provided in the energy transfer material where the vacant space part is provided through a region occupied with the energy transfer material or from a side of the region occupied with the energy transfer material toward an inside with a predetermined depth.

SYSTEM AND METHOD FOR PROVIDING COMPACT NAVIGATION-BASED SURGICAL GUIDE IN DENTAL IMPLANT SURGERY

A system and method for providing compact navigation-based surgical guide for dental implant surgery is disclosed. According to one embodiment, a surgical guide system comprise includes a surgical guide comprising having a tracking marker. The surgical guide is fabricated to be custom fitted to a patient's mouth or jawbone. The tracking marker is placed at an implant site according to a virtual implant plan. A sensor placed on a drill piece detects electromagnetic signals that are used to determine the position of the tracking marker. A computer in communication with the sensor processes the tracking marker data received from the sensor, determines a relative position of the drill piece with respect to the tracking marker, and provides real-time tracking of the drill piece on the display of the computer. 1. A surgical guide system comprising:a surgical guide comprising a tracking marker, wherein the surgical guide is fabricated to be custom fitted to a patient's mouth or jawbone, and the tracking marker is placed at an implant site according to a virtual implant plan;a drill piece comprising a sensor and a drill bit, wherein the sensor detects electromagnetic signals from the tracking marker and generates a relative position data of the tracking marker;a computer comprising a display and connected with the drill piece,wherein the computer receives the relative position data of the tracking marker from the sensor, determines a relative position of the tracking marker with respect to the drill piece using the relative position data of the tracking marker, correlates the relative position of the tracking marker to a predetermined virtual position of the tracking marker in the virtual implant plan, and provides real-time visual feedback of the drill piece on the display of the computer.2. The surgical guide system of claim 1 , wherein the tracking marker comprises three or more marking objects.3. The surgical guide system of claim 2 , wherein the computer determines the ...

SEMICONDUCTOR DEVICES

A semiconductor device includes an active pattern on a substrate, a gate structure buried at an upper portion of the active pattern, a bit line structure on the active pattern, a lower spacer structure covering a lower sidewall of the bit line structure, a contact plug structure on the active pattern and adjacent to the bit line structure, and a capacitor on the contact plug structure. The lower spacer structure includes first and second lower spacers that are sequentially stacked from the lower sidewall of the bit line structure in a horizontal direction that is substantially parallel to an upper surface of the substrate, the first lower spacer includes an oxide, and contacts the lower sidewall of the bit line structure, but does not contact the contact plug structure, and the second lower spacer includes a material different from any of the materials of the first lower spacer. 1. A semiconductor device comprising:an active pattern on a substrate;a gate structure buried at an upper portion of the active pattern;a bit line structure on the active pattern;a lower spacer structure covering a lower sidewall of the bit line structure;a contact plug structure on the active pattern and adjacent to the bit line structure; anda capacitor on the contact plug structure, the lower spacer structure includes first and second lower spacers that are sequentially stacked from the lower sidewall of the bit line structure in a horizontal direction that is substantially parallel to an upper surface of the substrate,', 'the first lower spacer includes an oxide, and contacts the lower sidewall of the bit line structure, but does not contact the contact plug structure, and', 'the second lower spacer includes a material different from any of the materials of the first lower spacer., 'wherein,'}2. The semiconductor device of claim 1 , wherein the first lower spacer includes an oxide.3. The semiconductor device of claim 1 , wherein the second lower spacer includes a nitride.4. The ...

VIRTUAL FLYING CAMERA SYSTEM

A virtual flying camera system is disclosed. According to one embodiment, the virtual flying camera system includes a plurality of cameras disposed along a track and spaced apart from each other, a recording system configured to receive input video streams from the plurality of cameras, and a control system configured to generate an output video stream from the input video streams. The output video stream includes a view of a virtually flying camera following a target at a user-adjustable speed. The control system generates the output video stream by merging a plurality of portions of the input video streams from adjacent cameras of the plurality of cameras. 1. A camera system comprising:a plurality of cameras disposed along a track and spaced apart from each other;a recording system configured to receive input video streams from the plurality of cameras; anda control system configured to generate an output video stream from the input video streams,wherein the output video stream includes a view of a virtually flying camera following a target at a user-adjustable speed, andwherein the control system generates the output video stream by merging a plurality of portions of the input video streams from adjacent cameras of the plurality of cameras.2. The camera system of further comprising a plurality of camera modules claim 1 , wherein a group of the plurality of cameras are mounted to each of the plurality of camera modules.3. The camera system of claim 1 , wherein the plurality of cameras are positioned at a predetermined interval.4. The camera system of claim 3 , wherein the control system determines a speed of the target based on time stamps of the input video stream and the predetermined interval between the plurality of cameras.5. The camera system of claim 1 , wherein the recording system includes a data interface configured to receive the input video streams from the plurality of cameras via a cable and a storage configured to record the input video streams.6. ...

SEMICONDUCTOR DEVICE AND METHOD OF FABRICATING THE SAME

In a method of fabricating a semiconductor device, sacrificial layer patterns are formed by leaving portions of sacrificial layers, instead of completely removing the sacrificial layers. Thus, the reliability of the semiconductor device may be increased, and the process of manufacturing the same may be simplified. 1. A semiconductor device , comprising:a first conductive line;a second conductive line formed at substantially the same height from a substrate as the first conductive line, wherein the first and second conductive lines are spaced apart from each other; anda first sacrificial layer pattern disposed between the first and second conductive lines,wherein the first sacrificial layer pattern has at least one concave sidewall.2. The semiconductor device of claim 1 , wherein the first and second conductive lines each have at least one sidewall which is curved toward the first sacrificial layer pattern.3. The semiconductor device of claim 1 , further comprising:a third conductive line disposed between the first conductive line and the substrate;a fourth conductive line disposed between the second conductive line and the substrate; andgate interlayer dielectric layers disposed between the first conductive line and the third conductive line and between the second conductive line and the fourth conductive line,wherein an etch rate of the first sacrificial layer pattern is different from an etch rate of the gate interlayer dielectric layers.4. The semiconductor device of claim 3 , further comprising a second sacrificial layer pattern disposed between the third conductive line and the fourth conductive line claim 3 ,wherein the second sacrificial layer pattern has at least one concave sidewall.5. The semiconductor device of claim 3 , wherein the third conductive line and the fourth conductive line contact each other.6. The semiconductor device of claim 1 , further comprising a dummy active pattern disposed between the first conductive line and the second conductive ...

PATIENT-SPECIFIC THREE-DIMENSIONAL DENTITION MODEL

A method and system for generating a color-textured three-dimensional dental model is specific to a patient is disclosed. According to one embodiment, a three-dimensional dental model that is deficient of volumetric data for a three-dimensional anatomical landmark is obtained. A two-dimensional anatomical landmark of a two-dimensional intra-oral photograph that corresponds to the three-dimensional anatomical landmark of the three-dimensional dental model is identified. The two-dimensional intra-oral photograph is projected onto the three-dimensional dental model. The three-dimensional anatomical landmark is calculated from the projection of the two-dimensional anatomical landmark of the two-dimensional intra-oral photograph. 1. A computer-implemented method comprising:receiving a three-dimensional dental model including three-dimensional volumetric data specific to a patient;receiving a plurality of two-dimensional intra-oral photographs specific to the patient;identifying a plurality of three-dimensional anatomical landmarks of the three-dimensional volumetric data;identifying a plurality of two-dimensional anatomical landmarks of the plurality of two-dimensional intra-oral photographs that correspond to the plurality of three-dimensional anatomical landmarks;projecting the plurality of two-dimensional intra-oral photographs onto the three-dimensional dental model based on the plurality of two-dimensional anatomical landmarks that correspond to the plurality of three-dimensional anatomical landmarks; andgenerating a patient-specific three-dimensional dental model including the three-dimensional volumetric data and the plurality of two-dimensional intra-oral photographs.2. The computer-implemented method of claim 1 , further comprising:dividing the three-dimensional dental model into a plurality of sections; andprojecting the plurality of two-dimensional intra-oral photographs onto the plurality of sections of the three-dimensional dental model.3. The computer- ...

GRAPHENE DEVICE AND METHOD OF OPERATING THE SAME

A graphene device and a method of operating the same are provided. The graphene device includes: an active layer including a plurality of meta atoms spaced apart from each other, each of the meta atoms having a radial shape, and a graphene layer that contacts each of the plurality of meta atoms; and a dielectric layer covering the active layer. 1. A graphene device comprising:a substrate; a plurality of meta atoms, each of the plurality of meta atoms comprising a first branch and a second branch intersecting the first branch, and', 'a graphene layer which is in contact with each of the plurality of meta atoms; and, 'an active layer disposed on the substrate, the active layer comprisinga dielectric layer disposed on the substrate, wherein the dielectric layer covers the active layer.2. The graphene device of claim 1 , wherein claim 1 , in at least one of the plurality of meta atoms claim 1 , the first branch comprises a first sub-meta atom and the second branch comprises a second sub-meta atom which intersects the first sub-meta atom in a shared partial region.3. The graphene device of claim 2 , wherein at least one of the first sub-meta atom and the second sub-meta atom has a bar shape.4. The graphene device of claim 2 , wherein at least one of the first sub-meta atom and the second sub-meta atom is symmetric with respect to the partial region.5. The graphene device of claim 2 , wherein both of the first sub-meta atom and the second sub-meta atom are symmetric with respect to an axis passing through the partial region.6. The graphene device of claim 2 , wherein at least one of the first sub-meta atom and the second sub-meta atom has a length which is shorter than a wavelength of light in a mid-infrared band.7. The graphene device of claim 6 , wherein at least one of the first sub-meta atom and the second sub-meta atom atoms has a length of about 1 μm to about 10 μm.8. The graphene device of claim 2 , wherein the first sub-meta atom has a thickness which is shorter ...

ADJUSTABLE ANATOMY DISPLAY TABLE

An adjustable anatomy display table is disclosed. According to one embodiment, the adjustable anatomy table includes a display configured to visualize the anatomy in a real size, a base configured to support the display, and an adjustable mechanism that mechanically couples the display to the base. The adjustable mechanism is configured to adjust a position of the display relative to the base. 1. An imaging system comprising:a display configured to visualize an image of an anatomy in a 1:1 life size of a patient, wherein the display has long sides and short sides;a base configured to support the display; andan adjustable mechanism that mechanically couples the display to the base,wherein the adjustable mechanism is configured to provide a plurality of adjustable positions of the display relative to the base,wherein the plurality of adjustable positions include a horizontal position in which the long sides and short sides of the display are in parallel to a ground at a same height and an upright position in which a first short side and a second short side of the short sides of the display are in parallel to the ground at different heights.2. The imaging system of claim 1 , wherein the plurality of adjustable positions further include an an upright position in which a first short side and a second short side of the short sides of the display are in parallel to the ground at different heights.3. The imaging system of claim 1 , wherein the adjustable mechanism is a tilting mechanism that is configured to tilt the display from the horizontal position to the upright position.4. The imaging system of claim 1 , wherein the adjustable mechanism further includes a rotational mechanism that is configured to rotate the display about a rotational axis.5. The imaging system of claim 1 , wherein the height adjusting mechanism is configured to adjust a height of the display in the horizontal position.6. The imaging system of claim 1 , wherein the anatomy is a human anatomy claim 1 ...

NEGATIVE ELECTRODE ACTIVE MATERIAL, NEGATIVE ELECTRODE INCLUDING NEGATIVE ELECTRODE ACTIVE MATERIAL, AND SECONDARY BATTERY INCLUDING NEGATIVE ELECTRODE

A negative electrode active material including silicon-based active material particles each including a core including SiO, wherein 0≤x≤2, and a coating layer present on the core. Also, a negative electrode active material in which the coating layer is any one of a carbon coating layer or a polymer coating layer, and the coating layer includes a fluorinated material including at least one of an alkali metal or an alkaline earth metal. 1. A negative electrode active material comprising:{'sub': 'x', 'b': '0', 'silicon-based active material particles comprising a core comprising SiO, wherein ≤x≤2, and a coating layer present on the core,'}wherein the coating layer is a carbon coating layer or a polymer coating layer, andthe coating layer comprises a fluorinated material comprising at least one selected from the group consisting of an alkali metal and an alkaline earth metal.2. The negative electrode active material of claim 1 , wherein the fluorinated material comprises at least one selected from the group consisting of LiF claim 1 , NaF and MgF.3. The negative electrode active material of claim 1 , wherein the fluorinated material is present in an amount of 0.1 wt % to 20 wt % claim 1 , based on a total weight of the coating layer.4. The negative electrode active material of claim 1 , wherein at least a part of the fluorinated material is spaced apart from the core.5. The negative electrode active material of claim 1 , wherein the silicon-based active material particles are in the form of single particles claim 1 , and{'sub': '50', 'an average particle diameter (D) of the silicon-based active material particles in the form of single particles is 0.1 μm to 50 μm.'}6. The negative electrode active material of claim 1 , wherein the silicon-based active material particles are in the form of primary particles agglomerated with each other to form secondary particles.7. The negative electrode active material of claim 6 , wherein an average particle diameter (D) of the ...

COMPOUNDS FOR TREATING SPINAL MUSCULAR ATROPHY

Provided herein are compounds, compositions thereof and uses therewith for treating spinal muscular atrophy. 110-. (canceled)13. (canceled)14. (canceled)17. The method of claim 16 , wherein Ris heterocyclyl selected from azetidinyl claim 16 , tetrahydrofuranyl claim 16 , pyrrolidinyl claim 16 , piperidinyl claim 16 , piperazinyl claim 16 , 1 claim 16 ,4-diazepanyl claim 16 , 1 claim 16 ,2 claim 16 ,5 claim 16 ,6-tetrahydropyridinyl claim 16 , 1 claim 16 ,2 claim 16 ,3 claim 16 ,6-tetrahydropyridinyl claim 16 , hexahydropyrrolo[3 claim 16 ,4-b]pyrrol-(1H)-yl claim 16 , (3aS claim 16 ,6aS)-hexahydropyrrolo[3 claim 16 ,4-b]pyrrol-(1H)-yl claim 16 , (3 aR claim 16 , 6aR)-hexahydropyrrolo[3 claim 16 ,4-b]pyrrol-(1H)-yl claim 16 , hexahydropyrrolo[3 claim 16 ,4-b]pyrrol-(2H)-yl claim 16 , (3aS claim 16 ,6aS)-hexahydropyrrolo[3 claim 16 ,4-b]pyrrol-(2H)-yl claim 16 , hexahydropyrrolo[3 claim 16 ,4-c]pyrrol-(1H)-yl claim 16 , (3aR claim 16 ,6aS)-hexahydropyrrolo[3 claim 16 ,4-c]pyrrol-(1H)-yl claim 16 , octahydro-5H-pyrrolo[3 claim 16 ,2-c]pyridinyl claim 16 , octahydro-6H-pyrrolo[3 claim 16 ,4-b]pyridinyl claim 16 , (4aR claim 16 ,7aR)-octahydro-6H-pyrrolo[3 claim 16 ,4-b]pyridinyl claim 16 , (4aS claim 16 ,7aS)-octahydro-6H-pyrrolo[3 claim 16 ,4-b]pyridinyl claim 16 , hexahydropyrrolo[1 claim 16 ,2-a]pyrazin-(2H)-one claim 16 , hexahydropyrrolo[1 claim 16 ,2-a]pyrazin-(1H)-yl claim 16 , (7R claim 16 ,8aS)-hexahydropyrrolo[1 claim 16 ,2-a]pyrazin-(1H)-yl claim 16 , (8aS)-hexahydropyrrolo[1 claim 16 ,2-a]pyrazin-(1H)-yl claim 16 , (8aR)-hexahydropyrrolo[1 claim 16 ,2-a]pyrazin-(1H)-yl claim 16 , (8aS)-octahydropyrrolo[1 claim 16 ,2-a]pyrazin-(1H)-yl claim 16 , (8aR)-octahydropyrrolo[1 claim 16 ,2-a]pyrazin-(1H)-yl claim 16 , octahydro-2H-pyrido[1 claim 16 ,2-a]pyrazinyl claim 16 , 3-azabicyclo[3.1.0]hexyl claim 16 , (1R claim 16 ,5S)-3-azabicyclo[3.1.0]hexyl claim 16 , 8-azabicyclo[3.2.1]octyl claim 16 , (1R claim 16 ,5S)-8-azabicyclo[3.2.1]octyl claim 16 , 8-azabicyclo[3.2 ...

COMPOUNDS FOR TREATING SPINAL MUSCULAR ATROPHY

Provided herein are compounds, compositions thereof and uses therewith for treating spinal muscular atrophy. In a specific embodiment, provided herein are compounds of a form that may be used to modulate the inclusion of exon 7 of SMN2 into mRNA that is transcribed from the SMN2 gene. In another specific embodiment, provided herein are compounds of a form that may be used to modulate the inclusion of exon 7 of SMN1 into mRNA that is transcribed from the SMN1 gene. In yet another embodiment, provided herein are compounds of a form that may be used to modulate the inclusion of exon 7 of SMN1 and SMN2 into mRNA that is transcribed from the SMN1 and SMN2 genes, respectively. 2. The compound of claim 1 , wherein:{'sub': 1', '2', '1', '2', '1', '2', '1', '2', '1', '1', '2', '2', '1', '2', '2', '1, 'wand ware C—Ror C—R; wherein, one of wand wis C—Rand the other is C—R, provided that, when wis C—R, then wis C—R; or, when wis C—R, then wis C—R;'}{'sub': 1', '1-8', '1-8', '1-8', '1-8', '2', '1-8', '1-8', '1-8', '1-8', '1-8', '1-8', '1-8', '2', '1-8', '1-8', '1-8', '1-8', '1-8', '1-8', '2', '1-8', '1-8', '1-8', '1-8', '1-8', '1-8', '1-8', '2', '1-8', '1-8', '1-8', '1-8', '1-8', '1-8', '2', '1-8', '1-8', '1-8', '1-8', '2', '1-8', '1-8', '2', '1-8', '1-8', '1-8', '1-8', '1-8', '1-8', '2', '1-8', '1-8', '1-8', '1-8', '1-8', '1-8', '2', '1-8', '1-8', '1-8', '1-8', '1-8', '2-8', '1-8', '2-8', '1-8', '2', '2-8', '2-8', '1-8', '2-8', '1-8', '2', '2-8', '1-8', '1-8', '2', '1-8', '1-8', '1-8', '1-8', '1-8', '2', '1-8', '1-8', '1-8', '1-8', '1-8', '2', '1-8', '1-8', '1-8', '1-8', '1-8', '1-8', '1-8', '2', '1-8', '1-8', '1-8', '1-8', '1-8', '2', '1-8', '1-8', '1-8', '1-8', '1-8', '2', '1-8', '1-8', '1-8', '1-8', '2', '1-8', '1-8', '1-8', '1-8', '1-8', '2', '1-8', '1-8', '1-8', '1-8', '1-8', '1-8', '1-8', '1-8', '1-8', '1-8', '1-8', '1-8', '2', '1-8', '1-8', '1-8', '1-8', '1-8', '2', '1-8', '1-8', '1-8', '1-8', '1-8', '1-8', '2', '1-8', '1-8', '1-8', '1-8', '1-8', '2', '1-8', '1-8', '1-8 ...

PHOTOELECTRIC DEVICE USING VALLEY-SPIN PHOTOELECTRON

Provided is a photoelectric device including a receiving part, a detecting part, and a connecting part. The receiving part may include a transition metal dichalcogenide layer and a charge inducing layer covering the transition metal dichalcogenide layer, and the detecting part may include a topological insulating layer spaced apart from the transition metal dichalcogenide layer. The connecting part may be provided to connect the transition metal dichalcogenide layer to the topological insulating layer. 1. A photoelectric device , comprising:a receiving part including a transition metal dichalcogenide layer and a charge inducing layer, the charge inducing layer covering the transition metal dichalcogenide layer;a detecting part including a topological insulating layer spaced apart from the transition metal dichalcogenide layer; anda connecting part connecting the transition metal dichalcogenide layer to the topological insulating layer.2. The device of claim 1 , wherein the detecting part further comprises first and second detection electrodes provided on the topological insulating layer.3. The device of claim 2 , wherein the transition metal dichalcogenide layer and the topological insulating layer are spaced apart from each other in a first direction claim 2 , andthe first and second detection electrodes are spaced apart from each other in a second direction intersecting the first direction.4. The device of claim 1 , wherein the connecting part comprises two portions claim 1 , one of which is provided on a top surface of the transition metal dichalcogenide layer claim 1 , and another of which is provided on a top surface of the topological insulating layer.5. The device of claim 1 , wherein the connecting part comprises graphene claim 1 , a carbon nanotube claim 1 , or a silicon membrane.6. The device of claim 1 , wherein the charge inducing layer is provided in the form of ionic gel.7. The device of claim 1 , further comprising a charge inducing electrode ...

INDUSTRIAL HIGH-TEMPERATURE MODIFICATION APPARATUS AND MODIFICATION METHOD

An industrial high temperature reformer and the reforming method in which a temperature of the reforming furnace is maintained at 1000° C. or higher by burning the coke, and a temperature of at least an upper half of the reforming furnace is maintained at 1200° C. or higher by burning the syngas, thereby producing syngas at a capacity of 500 m/hour or more by reforming all carbonaceous feedstock which is supplied to the reforming furnace. 18-. (canceled)9. An industrial high temperature reformer comprising:a reforming furnace reforming carbonaceous feedstock; a carbonaceous feedstock inlet supplying carbonaceous feedstock to the reforming furnace; a coke supply unit supplying coke to the reforming furnace; a first oxygen inlet supplying oxygen to the reforming furnace; a steam inlet supplying steam to the reforming furnace; a syngas outlet formed in an upper section of the reforming furnace; and a syngas inlet supplying syngas to the reforming furnace;wherein a temperature of the reforming furnace is maintained at 1000° C. or higher by burning the coke with the oxygen, and a temperature of at least an upper half of the reforming furnace is maintained at 1200° C. or higher by burning the syngas supplied via the syngas inlet.10. The industrial high temperature reformer of claim 9 , wherein the first oxygen inlet is formed in a lower section of the reforming furnace claim 9 , and a second oxygen inlet is formed in the mid-section of the reforming furnace.11. The industrial high temperature reformer of claim 10 , wherein the two carbonaceous feedstock inlets are formed in the mid-section of the reforming furnace claim 10 , and the second oxygen inlet is formed between the two carbonaceous feedstock inlets.12. The industrial high temperature reformer of claim 9 , wherein the oxygen supplied to the reforming furnace is fully used up to burn the coke and the syngas supplied via the syngas inlet.13. The industrial high temperature reformer of claim 9 , wherein the syngas ...

COMPOUNDS FOR TREATING SPINAL MUSCULAR ATROPHY

Provided herein are compounds, compositions thereof and uses therewith for treating spinal muscular atrophy. 115-. (canceled)17. The compound of claim 16 , wherein Ris heterocyclyl selected from azetidinyl claim 16 , tetrahydrofuranyl claim 16 , pyrrolidinyl claim 16 , piperidinyl claim 16 , piperazinyl claim 16 , 1 claim 16 ,4-diazepanyl claim 16 , 1 claim 16 ,2 claim 16 ,5 claim 16 ,6-tetrahydropyridinyl claim 16 , 1 claim 16 ,2 claim 16 ,3 claim 16 ,6-tetrahydropyridinyl claim 16 , hexahydropyrrolo[3 claim 16 ,4-b]pyrrol-(1H)-yl claim 16 , (3aS claim 16 ,6aS)-hexahydropyrrolo[3 claim 16 ,4-b]pyrrol-(1H)-yl claim 16 , (3aR claim 16 ,6aR)-hexahydropyrrolo[3 claim 16 ,4-b]pyrrol-(1H)-yl claim 16 , hexahydropyrrolo[3 claim 16 ,4-b]pyrrol-(2H)-yl claim 16 , (3 aS claim 16 ,6aS)-hexahydropyrrolo[3 claim 16 ,4-b]pyrrol-(2H)-yl claim 16 , hexahydropyrrolo[3 claim 16 ,4-c]pyrrol-(1H)-yl claim 16 , (3aR claim 16 ,6aS)-hexahydropyrrolo[3 claim 16 ,4-c]pyrrol-(1H)-yl claim 16 , octahydro-5H-pyrrolo[3 claim 16 ,2-c]pyridinyl claim 16 , octahydro-6H-pyrrolo[3 claim 16 ,4-b]pyridinyl claim 16 , (4aR claim 16 ,7aR)-octahydro-6H-pyrrolo[3 claim 16 ,4-b]pyridinyl claim 16 , (4aS claim 16 ,7aS)-octahydro-6H-pyrrolo[3 claim 16 ,4-b]pyridinyl claim 16 , hexahydropyrrolo[1 claim 16 ,2-a]pyrazin-(2H)-one claim 16 , hexahydropyrrolo[1 claim 16 ,2-a]pyrazin-(1H)-yl claim 16 , (7R claim 16 ,8aS)-hexahydropyrrolo[1 claim 16 ,2-a]pyrazin-(1H)-yl claim 16 , (8aS)-hexahydropyrrolo[1 claim 16 ,2-a]pyrazin-(1H)-yl claim 16 , (8aR)-hexahydropyrrolo[1 claim 16 ,2-a]pyrazin-(1H)-yl claim 16 , (8aS)-octahydropyrrolo[1 claim 16 ,2-a]pyrazin-(1H)-yl claim 16 , (8aR)-octahydropyrrolo[1 claim 16 ,2-a]pyrazin-(1H)-yl claim 16 , octahydro-2H-pyrido[1 claim 16 ,2-a]pyrazinyl claim 16 , 3-azabicyclo[3.1.0]hexyl claim 16 , (1R claim 16 ,5S)-3-azabicyclo[3.1.0]hexyl claim 16 , 8-azabicyclo[3.2.1]octyl claim 16 , (1R claim 16 ,5S)-8-azabicyclo[3.2.1]octyl claim 16 , 8-azabicyclo[3.2.1]oct-2-enyl claim 16 , ( ...

TETRAHYDROCARBAZOLES AS ACTIVE AGENTS FOR INHIBITING VEGF PRODUCTION BY TRANSLATIONAL CONTROL

The present invention relates to methods, compounds, and compositions for inhibiting angiogenesis. More particularly, the present invention relates to methods, compounds, and compositions for inhibiting VEGF production. 144.-. (canceled)4854-. (canceled) The present application claims priority to and the benefit under 35 U.S.C. §119 of U.S. Provisional Application No. U.S. Provisional Application No. 60/633,738, filed Dec. 6, 2004, which application is herein incorporated by reference in its entirety. The present application claims priority to and the benefit under 35 U.S.C. §119 of U.S. Provisional Application No. 60/629,889, filed Nov. 23, 2004, and U.S. Provisional Application No. 60/639,283, filed Dec. 27, 2004.The present invention relates to methods, compounds, and compositions for inhibiting angiogenesis. More particularly, the present invention relates to methods, compounds, and compositions for inhibiting VEGF production.Aberrant angiogenesis plays a critical role in the pathogenesis of numerous diseases, including malignant, ischemic, inflammatory and immune disorders (1, 2). The best-known of these disorders are cancer, exudative macular degeneration and diabetic retinopathy (DR), the last two of which are leading cause of blindness in the United States (3, 4). During the last decade our understanding of the molecular basis of angiogenesis has grown considerably. Numerous cytokines and growth factors that stimulate angiogenesis, such as VEGF, FGF-2, PDGF, IGF-1, TGF, TNFα, G-CSF have been identified (5-7). Among these growth factors, Vascular Endothelial Growth Factor (VEGF) plays a central role in angiogenesis (2).VEGF, also known as VEGF-A, was initially identified for its ability to induce vascular permeability and to promote vascular endothelial cell proliferation (8-10). VEGF is encoded by a single gene that gives rise to four isoforms by alternative splicing (11). All four isoforms share the same unusually long and GC rich 5′-UTR, as well as a 3′- ...

NEGATIVE ELECTRODE ACTIVE MATERIAL AND SECONDARY BATTERY INCLUDING THE SAME

The present disclosure relates to a negative electrode active material and a secondary battery including the same, and in particular, provides a negative electrode active material particle including a core including a carbon-based active material, and a shell surrounding the core and including a polymer, wherein silicon-based active material particles are embedded in the shell, and at least a part of the silicon-based active material particles are exposed to a surface of the shell. 1. A negative electrode active material particle comprising:a core including a carbon-based active material; anda shell surrounding the core and including a polymer,wherein silicon-based active material particles are embedded in the shell, and at least a part of the silicon-based active material particles are exposed to a surface of the shell.2. The negative electrode active material particle of claim 1 , wherein at least a part of the silicon-based active material particles in the negative electrode active material particle are present as being exposed to outside the surface of the shell.3. The negative electrode active material particle of claim 1 , wherein the silicon-based active material particles are separated from the core.4. The negative electrode active material particle of claim 1 , wherein the polymer is a polymer having a n-bond.5. The negative electrode active material particle of claim 1 , wherein the polymer is one or more types selected from the group consisting of poly(1-pyrenemethyl methacrylate) which is a homopolymer of pyrene claim 1 , poly(1-pyrenemethyl methacrylate-co-triethylene oxide methyl ether methacrylate) which is a copolymer of pyrene claim 1 , a polymer changing the pyrene side chain of the homopolymer or the copolymer of pyrene to anthracene claim 1 , polyparaphenylene claim 1 , polyaniline claim 1 , poly(9 claim 1 ,9-dioctylfluorene-co-fluorenone-co-methylbenzoic ester having a carbonyl group and methylbenzoic ester claim 1 , and polyacetylene having a ...

APPARATUS AND COMPUTER READABLE RECORDING MEDIUM FOR SITUATIONAL WARNING

An adverse situation warning device includes a route data storing portion for storing a first route data of a host vehicle including a first geohash corresponding to a moving route of the host vehicle, a route comparing portion for receiving a second route data of a remote vehicle including a second geohash corresponding to a moving route of the remote vehicle, and for comparing the geohash of the first route data and the geohash of the second route data, and a warning output portion for outputting an adverse situation warning based on the comparison result. 1. An adverse situation warning device , comprising:a computer;a route data storing portion of the computer for storing a first route data of a host vehicle including a first geohash corresponding to a moving route of the host vehicle;a route comparing portion of the computer for receiving a second route data of a remote vehicle including a second geohash corresponding to a moving route of the remote vehicle, and for comparing the geohash of the first route data and the geohash of the second route data; anda warning output portion of the computer for outputting an adverse situation warning based on the comparison result.2. The adverse situation warning device of claim 1 , wherein the route comparing portion compares a string of the geohash of the first route data and a string order of the geohash of the first route data with a string of the geohash of the second route data and a string order of the geohash of the second route data.3. The adverse situation warning device of claim 1 , wherein the route comparing portion receives the second route data from a remote server.4. The adverse situation warning device of claim 3 , wherein the route comparing portion monitors route data stored in the server through connection pooling.5. The adverse situation warning device of claim 1 , further comprising:a global positioning system (GPS) receiver for receiving at least one GPS signal and calculating a position coordinate ...

OPTICAL SENSOR

An optical sensor is disclosed. The optical sensor may include a substrate, a topological insulator layer formed on the substrate, an oxide layer formed on the topological insulator layer, a graphene layer stacked on the oxide layer, and a dielectric layer covering the graphene layer. 1. An optical sensor comprising:a substrate;a topological insulator layer formed on the substrate;an oxide layer formed on the topological insulator layer;a graphene layer stacked on the oxide layer; anda dielectric layer covering the graphene layer.2. The optical sensor of claim 1 , wherein the topological insulator layer is patterned so as to form a metamaterial and comprises a unit-cell array of the metamaterial.3. The optical sensor of claim 2 , wherein a unit cell of the unit-cell array has a slit pattern having at least one of a cross shape claim 2 , an X shape claim 2 , and an I shape.4. The optical sensor of claim 2 , wherein stacked structures of the topological insulator layer and the graphene layer are provided claim 2 , the stacked structures having an overlapping region of the topological insulator layer and the graphene layer claim 2 , andwherein the topological insulator layer extends in a first direction, and the graphene layer extends in a second direction other than the first direction.5. The optical sensor of claim 4 , wherein the first direction and the second direction cross each other.6. The optical sensor of claim 4 , wherein an array of the stacked structures of the topological insulator layer and the graphene layer is provided.7. The optical sensor of claim 1 , wherein electrodes are provided at both ends of the graphene layer.8. The optical sensor of claim 1 , wherein the oxide layer has a thickness of 10 nm or less.9. The optical sensor of claim 1 , wherein the dielectric layer is an ion gel layer comprising ion gel.10. The optical sensor of claim 9 , further comprising a side gate electrode electrically connected to the ion gel layer and configured to gate ...

LAUNDRY TREATMENT MACHINE AND CONTROL METHOD THEREOF

A laundry treatment machine may include: a tub; a drum that is rotatably disposed in the tub; an actuator that provides power for rotating the drum; and a balancer device that is disposed at an end where the inlet hole of the drum is formed, and adjusts the center of gravity of the drum that is rotating. The balancer device may include: a main balancer that reduces vibration of the drum by moving in the opposite direction to eccentricity that is generated when the drum is rotated; a first sub-balancer of which an arrangement gap from the main balancer is adjusted in accordance with the degree of eccentricity of the drum; and a second sub-balancer of which an arrangement gap from the main balancer is adjusted in the opposite direction of the first sub-balancer with respect to the main balancer. 1. A laundry treatment machine comprising:a tub;a drum rotatably disposed in the tub and having an inlet;an actuator to provide power for rotating the drum; anda balancer device disposed at an end of the drum where the inlet is provided, and the balancer device to adjust a center of gravity of the drum, a main balancer that reduces vibration of the drum by moving to a location opposite to eccentricity that is generated when the drum is rotated;', 'a first sub-balancer that moves relative to the main balancer and changes a first gap from the main balancer based on a degree of eccentricity of the drum; and', 'a second sub-balancer that moves relative to the main balancer and changes a second gap from the main balancer, wherein the second sub-balancer is moved away from the main balancer in a different direction than the first sub-balancer is moved away from the main balancer., 'wherein the balancer device includes2. The laundry treatment apparatus of claim 1 , wherein the first sub-balancer and the second sub-balancer have a same weight claim 1 , and the first gap is a same distance as the second gap.3. The laundry treatment apparatus of claim 1 , wherein the balancer device ...

NOVEL DIPHENYLMETHANE DERIVATIVES AS SGLT2 INHIBITORS

A compound with a diphenylmethane moiety having an inhibitory activity against sodium-dependent glucose cotransporter 2 (SGLT2) being present in the intestine and kidney is disclosed. A pharmaceutical composition including the compound as an active ingredient, which is useful for preventing or treating metabolic disorders, particularly diabetes is disclosed. A method for preparing the compound, and a method for preventing or treating metabolic disorders, particularly diabetes, by using the compound is provided. 5. The compound of , wherein said ring A is a benzene , indane , indene , tetrahydronaphthalene , dihydronaphthalene ring , which is optionally substituted with a substituent as defined in .6. The compound of , wherein said ring B is a quinoline , quinoxaline , 3 ,4-dihydro-2H-benzo[b][1 ,4]dioxepine , 2 ,3-dihydrobenzo[b]thiophene , indazole , indole , 2 ,3-dihydrobenzo[b][1 ,4]dioxine , benzodioxole , indane , tetrahydronaphthalene , 3 ,4-dihydro-2H-thiochromene , dihydrobenzofuran , benzo[d][1 ,3]oxathiole , tetrahydroquinoline , or 3 ,4-dihydro-2H-benzo[b][1 ,4]oxazine ring , which is optionally substituted with a substituent as defined in .7. The compound of claim 1 , which is selected from the group consisting of:(1) (2S,3R,4R,5S,6R)-2-(7-bromo-6-(4-methoxybenzyl)-2,3-dihydro-1H-inden-4-yl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol;(2) (2S,3R,4R,5S,6R)-2-(7-bromo-6-(4-ethoxybenzyl)-2,3-dihydro-1H-inden-4-yl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol;(3) (2S,3R,4R,5S,6R)-2-(7-bromo-6-(4-ethylbenzyl)-2,3-dihydro-1H-inden-4-yl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol;(4) (2S,3R,4R,5S,6R)-2-(7-chloro-6-(4-methoxybenzyl)-2,3-dihydro-1H-inden-4-yl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol;(5) (2S,3R,4R,5S,6R)-2-(7-fluoro-6-(4-methoxybenzyl)-2,3-dihydro-1H-inden-4-yl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol;(6) (2R,3S,4R,5R,6S)-2-(hydroxymethyl)-6-(6-(4-methoxybenzyl)-7-methyl-2,3-dihydro-1H-inden-4-yl)tetrahydro-2H- ...

IMAGE SENSOR DEVICE

An image sensor device includes a pixel array, including digital pixels, and a pixel driver including a high-speed scanner that generates reset enable signals and signal enable signals. Each of the digital pixels includes a photo detector, a comparator, and a memory circuit. The high-speed scanner includes a first flip-flop and a second flip-flop. The first flip-flop receives a clock signal and a read trigger signal and outputs a first reset enable signal of the reset enable signals. The second flip-flop receives the clock signal and the first reset enable signal and outputs a first signal enable signal of the signal enable signals. The pixel array outputs a reset sampling value stored in the memory circuit in response to the first reset enable signal and outputs a signal sampling value stored in the memory circuit in response to the first signal enable signal. 1. An image sensor device comprising:a pixel array including a plurality of digital pixels;a pixel driver including a high-speed scanner configured to generate reset enable signals and signal enable signals and configured to control the plurality of digital pixels; anda digital logic circuit configured to perform a digital signal processing operation on a digital signal output from the plurality of digital pixels, wherein:each of the plurality of digital pixels includes a photo detector, a comparator, and a memory circuit, a first flip-flop configured to receive a clock signal and a read trigger signal and to output a first reset enable signal of the reset enable signals; and', 'a second flip-flop configured to receive the clock signal and the first reset enable signal and to output a first signal enable signal of the signal enable signals, and, 'the high-speed scanner includesthe pixel array outputs a reset sampling value stored in the memory circuit in response to the first reset enable signal and outputs a signal sampling value stored in the memory circuit in response to the first signal enable signal.2. ...

NEGATIVE ELECTRODE ACTIVE MATERIAL, NEGATIVE ELECTRODE INCLUDING THE SAME, AND SECONDARY BATTERY INCLUDING THE NEGATIVE ELECTRODE

The present invention relates to a negative electrode active material including a carbonaceous matrix having a first particle and a second particle, wherein the first particle includes a silicon core, an oxide layer disposed on the silicon core and including SiO(0 Подробнее

NOVEL CRYSTALLINE FORM OF 5-CHLORO-N-(METHYL)THIOPHENE-2-CARBOXAMIDE METHANESULFONATE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME

The present invention relates to a novel crystalline form of 5-chloro-N-({(5S)-2-oxo-3-[4-(5,6-dihydro-4H-[1,2,4]triazin-1-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene-2-carboxamide methanesulfonate and a pharmaceutical composition containing the same. The novel crystalline form of a compound according to the present invention exhibits excellent stability even in high-temperature and humidity environments, and thus can be favorably used to prevent or treat diseases, such as thrombosis, myocardial infarction, atherosclerosis, inflammation, stroke, angina pectoris, restenosis after angioplasty, and thromboembolism. 1. An anhydrous crystalline 5-chloro-N-({(5S)-2-oxo-3-[4-(5 ,6-dihydro-4H-[1 ,2 ,4]triazin-1-yl)phenyl]-1 ,3-oxazolidin-5-yl}methyl) thiophene-2-carboxamide methanesulfonate (GCC-4401C) , whose X-ray powder diffraction spectrum using Cu-Kα radiation comprises peaks at an angle of diffraction 2θ of 4.302 , 8.621 , 9.606 , 12.103 , 12.879 , 15.648 , 17.353 , 17.949 , 19.26 , 19.577 , 20.252 , 21.792 , 23.108 , 23.356 , 25.76 and 27.463.2. The anhydrous crystalline GCC-4401C of claim 1 , which shows a peak at 178±2° C. in a differential scanning calorimetry (DSC) analysis.3. An anhydrous crystalline 5-chloro-N-({(5S)-2-oxo-3-[4-(5 claim 1 ,6-dihydro-4H-[1 claim 1 ,2 claim 1 ,4]triazin-1-yl)phenyl]-1 claim 1 ,3-oxazolidin-5-yl}methyl) thiophene-2-carboxamide methanesulfonate claim 1 , whose X-ray powder diffraction spectrum using Cu-Kα radiation comprises peaks at an angle of diffraction 2θ of 12.022 claim 1 , 15.721 claim 1 , 15.971 claim 1 , 18.125 claim 1 , 18.928 claim 1 , 19.979 claim 1 , 20.311 claim 1 , 20.726 claim 1 , 21.66 claim 1 , 22.805 claim 1 , 23.18 claim 1 , 23.985 claim 1 , 25.857 claim 1 , 27.25 claim 1 , 27.829 claim 1 , 28 claim 1 , 28.189 and 29.753.4. The anhydrous crystalline 5-chloro-N-({(5S)-2-oxo-3-[4-(5 claim 3 ,6-dihydro-4H-[1 claim 3 ,2 claim 3 ,4]triazin-1-yl)phenyl]-1 claim 3 ,3-oxazolidin-5-yl}methyl) thiophene-2-carboxamide ...

NEGATIVE ELECTRODE ACTIVE MATERIAL, NEGATIVE ELECTRODE INCLUDING THE SAME, SECONDARY BATTERY INCLUDING THE NEGATIVE ELECTRODE, AND PREPARATION METHOD OF THE NEGATIVE ELECTRODE ACTIVE MATERIAL

A negative electrode active material including a silicon-carbon-based particle, the silicon-carbon-based particle having a SiCmatrix and boron doped in the SiCmatrix, wherein x of the SiCmatrix is 0.3 or more and less than 0.6. 1. A negative electrode active material , comprising: [{'sub': 'x', 'a SiCmatrix; and'}, {'sub': 'x', 'boron doped in the SiCmatrix,'}], 'a silicon-carbon-based particle, wherein the silicon-carbon-based particle comprises{'sub': 'x', 'wherein x of the SiCmatrix is 0.3 or more and less than 0.6.'}2. The negative electrode active material of claim 1 ,wherein the boron is present in an amount of 0.5 wt % to 1 wt % based on a total weight of the silicon-carbon-based particle.3. The negative electrode active material of claim 1 ,{'sub': '50', 'wherein an average particle diameter (D) of the silicon-carbon-based particles is 1 μm to 10 μm.'}4. The negative electrode active material of claim 1 ,{'sub': 'x', 'wherein the SiCmatrix comprises SiC and Si.'}5. The negative electrode active material of claim 1 , wherein the boron is present inside the SiCmatrix.6. A method for preparing a negative electrode active material claim 1 , the method comprising:forming a matrix fluid by performing a first heat treatment wherein vaporized silicon source, carbon source, and carrier gas are introduced into a first reaction furnace; andreacting the matrix fluid and boron in the gaseous state to form a SiC matrix doped with boron, wherein{'sub': 'x', 'x of the SiCmatrix is 0.3 or more and less than 0.6.'}7. The method of claim 6 ,wherein in the step of forming of the matrix fluid,a ratio of an inflow rate of the vaporized silicon source to an inflow rate of the carbon source is 1:0.3 to 1:0.6.8. The method of claim 6 ,wherein the first heat treatment is performed at a temperature range of 1500° C. to 2500° C.9. The method of claim 6 ,wherein the carrier gas is at least one selected from the group consisting of Ar, He, and Ne.10. The method of claim 6 ,{'sub': 'x', ' ...

COMPOUNDS FOR TREATING SPINAL MUSCULAR ATROPHY

Provided herein are compounds, compositions thereof and uses therewith for treating spinal muscular atrophy. 6. The compound of claim 1 , wherein the form is selected from a free acid claim 1 , free base claim 1 , salt claim 1 , isotopologue claim 1 , stereoisomer claim 1 , racemate claim 1 , enantiomer claim 1 , diastereomer or tautomer thereof.7. The compound of claim 6 , wherein the salt form is a chloride claim 6 , hydrobromide claim 6 , hydrochloride claim 6 , dihydrochloride claim 6 , acetate claim 6 , trifluoroacetate or trifluoroacetic acid salt.8. The compound of claim 1 , wherein the compound is selected from the group consisting of:3-(1,3-benzothiazol-2-yl)-7-(piperazin-1-yl)-2H-pyrano[2,3-b]pyridin-2-one3-(4-chloro-1,3-benzothiazol-2-yl)-7-(piperazin-1-yl)-2H-pyrano[2,3-b]pyridin-2-one3-(1,3-benzothiazol-2-yl)-7-(4-methylpiperazin-1-yl)-2H-pyrano[2,3-b]pyridin-2-one3-(1,3-benzothiazol-2-yl)-7-[4-(2-chloroethyl)piperazin-1-yl]-2H-pyrano[2,3-b]pyridin-2-one3-(4-chloro-1,3-benzothiazol-2-yl)-7-(4-methylpiperazin-1-yl)-2H-pyrano[2,3-b]pyridin-2-one3-(4-chloro-1,3-benzothiazol-2-yl)-7-[4-(2-hydroxybenzyl)piperazin-1-yl]-2H-pyrano[2,3-b]pyridin-2-onetert-butyl 4-[3-(1,3-benzothiazol-2-yl)-2-oxo-2H-pyrano[3,2-c]pyridin-7-yl]piperazine-1-carboxylatetert-butyl 4-[3-(4-chloro-1,3-benzothiazol-2-yl)-2-oxo-2H-pyrano[3,2-c]pyridin-7-yl]piperazine-1-carboxylate3-(4-chloro-1,3-benzothiazol-2-yl)-7-(piperazin-1-yl)-2H-pyrano[3,2-c]pyridin-2-one3-(4-chloro-1,3-benzothiazol-2-yl)-7-[4-(2-hydroxyethyl)piperazin-1-yl]-2H-pyrano[2,3-b]pyridin-2-one3-(4-chloro-1,3-benzothiazol-2-yl)-7-(4-methylpiperazin-1-yl)-2H-pyrano[3,2-c]pyridin-2-one3-(4-chloro-1,3-benzothiazol-2-yl)-7-(4-ethylpiperazin-1-yl)-2H-pyrano[2,3-b]pyridin-2-one3-(4-chloro-1,3-benzothiazol-2-yl)-7-(4-propylpiperazin-1-yl)-2H-pyrano[2,3-b]pyridin-2-one3-(1,3-benzothiazol-2-yl)-7-(4-methylpiperazin-1-yl)-2H-pyrano[3,2-c]pyridin-2-one3-(4-methyl-1,3-thiazol-2-yl)-7-(piperazin-1-yl)-2H-pyrano[2,3-b]pyridin-2-one7-( ...

Smart raw cotton total management system

Provided is a smart raw cotton total management system and more particularly, a smart raw cotton total management system which promotes efficiency of raw cotton management by providing a variety of evaluation information on the raw cotton purchased by the member to the member side and totally manages a raw cotton member and a raw cotton supplier by providing purchase prior information to the member when requesting the raw cotton purchase of the member to perform reasonable raw cotton purchase and transaction.

DEVICE AND METHOD FOR TRANSMITTING AND RECEIVING FEEDBACK INFORMATION IN WIRELESS COMMUNICATION SYSTEM

Disclosed is a 5generation (5G) or pre-5G communication system to be provided for supporting a data transmission rate higher than that of a 4generation (4G) communication system such as long term evolution (LTE). Examples of the present invention provide a beam selection and feedback device and method for minimizing complexity and overhead without performance deterioration in a beamforming MIMO wireless communication system. According to one example of the present invention, an apparatus of a receiving device in a wireless communication system comprises: a transceiver; and at least one processor, wherein the at least one processor is configured to: select at least one beam pair from among a plurality of transmission/reception beam pairs, and control the transceiver to transmit feedback information including indication information indicating whether the at least one beam pair is identical to a beam pair selected in a previous beamforming procedure. 1. A method for operating a receiving device in a wireless communication system , the method comprising:selecting at least one beam pair from among a plurality of transmission/reception beam pairs;transmitting feedback information including indication information indicating whether the at least one beam pair is identical to a beam pair selected in a previous beamforming procedure.2. The method of claim 1 , wherein the transmitting the feedback information comprises:when the beam pair selected in the previous beamforming procedure is identical to the at least one beam pair, transmitting the feedback information including indication information indicating that the beams are not changed.3. The method of claim 1 , wherein the transmitting the feedback information comprises:when the beam pair selected in the previous beamforming procedure is different from the at least one beam pair, transmitting the feedback information including indication information indicating that the beams are changed and information on the at least one ...

FUSED RING HETEROARYL COMPOUNDS AND THEIR USE AS TRK INHIBITORS

The disclosure provides novel chemical compounds represented by Formula I or a pharmaceutically acceptable salt, solvate, polymorph, ester, tautomer or prodrug thereof. The compounds can be used as an inhibitor of Trk and are useful in the treatment of pain, cancer, inflammation, neurodegenerative disease and certain infectious diseases. 2. The compound of claim 1 , wherein Ra phenyl ring substituted with one or more substituent groups are independently selected from the group consisting of fluorine claim 1 , methoxy and ethoxy claim 1 , wherein Rand Rare H claim 1 , wherein Ris selected from the group consisting of H claim 1 , methyl claim 1 , ethyl claim 1 , iso-propyl claim 1 , cyclopropyl claim 1 , t-butyl claim 1 , methoxyethyl and hydroxyethyl.3. The compound of claim 1 , wherein Ris a pyridine ring substituted with at least one selected from the group consisting of fluorine and methoxy claim 1 , wherein Rand Rare H claim 1 , wherein Ris selected from the group consisting of H claim 1 , methyl claim 1 , ethyl claim 1 , iso-propyl claim 1 , cyclopropyl claim 1 , t-butyl claim 1 , methoxyethyl and hydroxyethyl.4. The compound of claim 1 , wherein Ris a pyrid-2-on-3-yl ring optionally substituted with one or more substituent groups independently selected from the group consisting of halogen and C1-C4 alkyl.5. The compound of claim 1 , wherein when —NRRdoes not form a ring structure claim 1 , Ris selected from the group consisting of hydrogen claim 1 , linear C1-C6 alkyl and branched C1-C6 alkyl claim 1 , and Ris selected from the group consisting of linear C1-C6 fluoroalkyl claim 1 , branched C1-C6 fluoroalkyl claim 1 , linear C1-C6 difluoroalkyl claim 1 , branched C1-C6 difluoroalkyl claim 1 , linear C1-C6 trifluoroalkyl claim 1 , branched C1-C6 trifluoroalkyl claim 1 , linear C1-C6 hyroxyalkyl claim 1 , branched C1-C6 hyroxyalkyl claim 1 , linear C2-C6 difluoroalkyl claim 1 , and branched C2-C6 difluoroalkyl.6. The compound of claim 1 , wherein —NRRforming a 4- ...

MULTIVISION DISPLAY APPARATUS

A multivision display apparatus which enables participants who conduct a video conference to conduct the video conference in a manner in which the participants keep eye contact with each other. The multivision display apparatus includes a plurality of display apparatuses which output images, a bezel provided on an edge of each of the plurality of display apparatuses, a light receiving device which is provided on the bezel positioned at the center of a screen formed with the plurality of display apparatuses to have a vertical length, and receives an image, and an image receiving device which is provided on an upper end of the bezel to be connected to the light receiving device, receives the image received by the light receiving device, generates image data, and transmits the image data to the display apparatuses. 1. A multivision display apparatus comprising:a plurality of display apparatuses which output images;a bezel provided on an edge of each of the plurality of display apparatuses;a light receiving device which is provided on the bezel positioned at a center of a screen formed with the plurality of display apparatuses to have a vertical length, and receives an image; andan image receiving device which is provided on an upper end of the bezel to be connected to the light receiving device, receives the image received by the light receiving device, generates image data, and transmits the image data to the display apparatuses.2. The multivision display apparatus of claim 1 , wherein the light receiving device includes:a light receiver which receives an image from an external source;a body tube which connects the light receiver and the image receiving device; anda reflector which is provided inside the body tube, reflects the image received by the light receiver to the image receiving device.3. The multivision display apparatus of claim 2 , wherein the light receiver is provided with a lens to receive the image from the external source.4. The multivision display ...

DISPLAY APPARATUS

A display apparatus includes a display module, a supporting device provided to support and turn the display module, and a holding device provided for a mobile device to be coupled to the display module. The supporting device rotatably supports the display module and includes a motor providing a driving force to turn the display module. The holding device supports a mobile device so that the mobile device may be coupled to the display module. The holding device comprises a mounting part provided to be mounted onto the display module and a holder rotatably coupled to the mounting part and provided to support the mobile device. 1. A display apparatus comprising:a display module;a support configured to rotatably support the display module, and including a motor configured to provide a driving force to rotate the display module; anda holding device configured to be mounted on the display module and configured to support a mobile device, the holding device comprising a mounting part configured to be mounted on the display module and a holder rotatably coupled to the mounting part and configured to support the mobile device.2. The display apparatus of claim 1 , wherein the holding device is configured to be mounted at any location along edges of the display module.3. The display apparatus of claim 1 , wherein the holding device is configured such that when the holding device is mounted on the display module and the holder supports the mobile device claim 1 , a full area of a front surface or a rear surface of the mobile device is positioned outside the display module.4. The display apparatus of claim 1 , wherein the display module comprises a frame defining edges of the display module.5. The display apparatus of claim 4 , wherein the frame comprisesa front surface having an end extending to a screen display region of the display module,a side surface connected to an other end of the front surface and inclined backwards from the screen display region, the side surface being ...

NEGATIVE ELECTRODE ACTIVE MATERIAL, NEGATIVE ELECTRODE COMPRISING THE NEGATIVE ELECTRODE ACTIVE MATERIAL, AND SECONDARY BATTERY COMPRISING THE NEGATIVE ELECTRODE

A negative electrode active material which includes a secondary particle including first primary particles, wherein the first primary particle includes a core including SiO, wherein 0≤x<2, an intermediate layer which covers at least a portion of a surface of the core and includes silicon nitride, silicon oxynitride, or a mixture thereof, and a carbon coating layer which covers at least a portion of the intermediate layer and includes nitrogen-doped carbon, and a negative electrode and a lithium secondary battery which include the same. 1. A negative electrode active material , comprising:a secondary particle, comprising first primary particles, [{'sub': 'x', 'a core comprising SiO, wherein 0≤x<2;'}, 'an intermediate layer which covers at least a portion of a surface of the core and comprises silicon nitride, silicon oxynitride, or a mixture thereof; and', 'a carbon coating layer which covers at least a portion of the intermediate layer and comprises nitrogen-doped carbon., 'wherein the first primary particles comprise'}2. The negative electrode active material of claim 1 , wherein at least one of the core claim 1 , the intermediate layer claim 1 , and the carbon coating layer of the primary particle comprises a metal compound.3. The negative electrode active material of claim 1 , wherein claim 1 , in addition to the first primary particles claim 1 , the secondary particle further comprises [{'sub': 'x', 'a core comprising SiO, wherein 0≤x<2;'}, 'an intermediate layer which covers at least a portion of a surface of the core and comprises silicon nitride, silicon oxynitride, or a mixture thereof; and', 'a carbon coating layer which covers at least a portion of the intermediate layer and comprises nitrogen-doped carbon,', 'wherein at least one of the core, the intermediate layer, and the carbon coating layer of the metal compound-doped primary particles comprises a metal compound., 'metal compound-doped primary particles which comprise'}4. The negative electrode active ...

DISPLAY APPARATUS

Disclosed herein is a display apparatus. The display apparatus includes a housing, a display configured to protrude out from the housing along a vertical axis, a lifting device configured to raise and to lower the display along the vertical axis with respect to the housing, and a position sensor disposed inside the housing and configured to sense a distance in which an upper portion of the display is moved along the vertical axis. The position sensor includes a first position sensor and a second position sensor spaced apart along a horizontal axis. The first position sensor and the second position sensor simultaneously sense a distance by which the display is raised. 1. A display apparatus comprising:a housing;a display configured to protrude out from the housing along a vertical axis;a lifting device configured to raise and to lower the display along the vertical axis with respect to the housing; anda position sensor disposed inside the housing and configured to sense a distance in which an upper portion of the display is moved along the vertical direction, a first position sensor; and', 'a second position sensor spaced apart along a horizontal axis,', 'wherein the first position sensor and the second position sensor simultaneously sense a distance by which the display is raised., 'wherein the position sensor comprises2. The display apparatus of claim 1 , whereinthe first position sensor and the second position sensor are optical sensors.3. The display apparatus of claim 2 , wherein the display comprises:a first reflector disposed in the upper portion of the display and disposed at a position corresponding to the first position sensor along the vertical axis, anda second reflector disposed in the upper portion of the display and disposed at a position corresponding to the second position sensor along the vertical axis.4. The display apparatus of claim 3 , wherein the display further comprises:a flexible display panel on which a screen is displayed in a first ...

DISPLAY APPARATUS

A display apparatus includes a display module, a support configured to rotate and support the display module, and a mounting device configured to mount a mobile device on the display module. The mobile device is configured to be paired with the display module. The mounting device includes a mounting portion including a mounting groove having a shape corresponding to a frame forming borders of the display module. The mounting portion is coupled to the frame when the frame is inserted into the mounting groove, and an accommodating portion is positioned below the mounting portion, and accommodates the mobile device such that the mobile device is mounted on the display module. 1. A display apparatus comprising:a display module including a screen display area, and a frame forming borders of the screen display area;a support configured to rotatably support the display module, and including a motor configured to provide a driving force to rotate the display module; anda mounting device configured to be coupled to the display module and configured to mount a mobile device on the display module, the mounting device comprising a mounting portion having a shape configured to receive the frame and having an accommodating portion extending from the mounting portion and configured to accommodate the mobile device.2. The display apparatus according to claim 1 , wherein the display module comprises a longer side and a shorter side claim 1 , so that:when the display module is at a first position, the longer side is positioned in a vertical direction, andwhen the display module is at a second position, the longer side is positioned in a horizontal direction.3. The display apparatus according to claim 2 , wherein claim 2 , when the display module is at the first position claim 2 , the mounting device is configured to be mounted at a top end of the display module.4. The display apparatus according to claim 1 , wherein the accommodating portion is positioned below the mounting portions ...

Mobile terminal and method of controlling the mobile terminal

A mobile terminal including a display unit on which objects corresponding to at least one selected application from among multiple applications executable on the mobile terminal are output in a locked mode; a user identification unit that identifies at least one user of the mobile terminal and determines whether the at least one user is authorized to cancel the locked mode; and a controller that only grants access for at least one individually assigned application among the multiple applications to the user authorized to cancel the locked mode of the mobile terminal. The at least one user has access to only at least one assigned function among multiple functions included in the at least one individually assigned application.

METHOD FOR DUAL INHIBITION OF SGLT1 AND SGLT2 USING DIPHENYLMETHANE DERIVATIVES

The present invention relates to a method for dual inhibition of sodium-dependent glucose cotransporter 1 (SGLT1) and sodium-dependent glucose cotransporter 2 (SGLT2) present in the intestine and kidney by using the compound of formula I or a pharmaceutically acceptable salt or a prodrug thereof: 5. The method of , wherein said ring A is a benzene , indane , indene , dihydrobenzofuran , dihydroisobenzofuran , benzofuran , dihydrobenzothiophene , benzothiophene , tetrahydronaphthalene , dihydronaphthalene , chroman , chromene , isochroman , isochromene , benzodioxole , benzodioxane , benzooxazine , tetrahydroquinoline , tetrahydroquinoxaline , tetrahydroisoquinoline , indazole , indole , indoline , benzoimidazole , benzooxazole , benzothiazole , benzotriazole , quinazoline , quinoxaline , cinnoline , phthalazine , or benzotriazine ring , which is optionally substituted with a substituent as defined in .6. The method of , wherein said ring B is a quinoline , quinoxaline , 3 ,4-dihydro-2H-benzo[b][1 ,4]dioxepine , 2 ,3-dihydrobenzo[b]thiophene , indazole , indole , 2 ,3-dihydrobenzo[b][1 ,4]dioxine , benzodioxole , indane , tetrahydronaphthalene , 3 ,4-dihydro-2H-thiochromene , dihydrobenzofuran , benzo[d][1 ,3]oxathiole , tetrahydroquinoline , or 3 ,4-dihydro-2H-benzo[b][1 ,4]oxazine ring , which is optionally substituted with a substituent as defined in .7. The method of claim 1 , wherein the compound of formula I is selected from the group consisting of:(1) (2S,3R,4R,5S,6R)-2-(7-bromo-6-(4-methoxybenzyl)-2,3-dihydro-1H-inden-4-yl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol;(2) (2S,3R,4R,5S,6R)-2-(7-bromo-6-(4-ethoxybenzyl)-2,3-dihydro-1H-inden-4-yl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol;(3) (2S,3R,4R,5S,6R)-2-(7-bromo-6-(4-ethylbenzyl)-2,3-dihydro-1H-inden-4-yl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol;(4) (2S,3R,4R,5S,6R)-2-(7-chloro-6-(4-methoxybenzyl)-2,3-dihydro-1H-inden-4-yl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol;(5) (2S,3R, ...

Memory device, memory system, and method of operating memory device

A method of operating a memory device includes: checking for errors in data read from a first address of a memory cell array of the memory device; counting the number of errors that occurred in the data read from the first address; receiving a first command for data read from the first address; determining whether the number of errors that occurred in the data read from the first address is greater than or equal to a first value; and mapping the first address to a second address, if the number of errors that occurred in the data read from the first address is greater than or equal to the first value.

Refrigerator and controlling method thereof

Provided is a refrigerator including: a storage compartment in which a plurality of accommodation spaces are disposed; a detection unit that detects a storage container accommodated in the plurality of accommodation spaces; a display unit that displays accommodation information regarding the plurality of accommodation spaces; and a controller that controls the display unit so as to display the accommodation spaces in which a new storage container may be accommodated, based on a result of detection of the detection unit.

Method and device for searching new material

A method for searching a new material includes: performing a learning on a material model, which is modeled based on a known material; determining a candidate material by inputting a targeted physical property to a result of the learning; and determining the new material from the candidate material.

NEGATIVE ELECTRODE ACTIVE MATERIAL AND LITHIUM SECONDARY BATTERY INCLUDING THE SAME

The present invention relates to a silicon-carbon-based composite negative electrode active material, and a negative electrode for a secondary battery and a lithium secondary battery including the same, and particularly to a silicon-carbon-based composite negative electrode active material, in which physical stability is improved by including a carbon-based core capable of intercalating and deintercalating lithium ions and at least one silicon particle included in the carbon-based core and disposed in the form of being distributed in an outer portion of the carbon-based core, and a negative electrode for a secondary battery and a lithium secondary battery in which life characteristics are improved by including the same. 1. A silicon-carbon-based composite negative electrode active material comprising:a carbon-based core capable of intercalating and deintercalating lithium ions; andat least one silicon particle included in the carbon-based core and disposed in a form of being distributed in an outer portion of the carbon-based core.2. The silicon-carbon-based composite negative electrode active material of claim 1 , wherein the carbon-based core comprises a single material selected from the group consisting of natural graphite claim 1 , artificial graphite claim 1 , graphite claim 1 , graphitizable carbon claim 1 , non-graphitizable carbon claim 1 , carbon black claim 1 , and graphite oxide claim 1 , or a mixture of two or more thereof.3. The silicon-carbon-based composite negative electrode active material of claim 1 , wherein an average particle diameter of the carbon-based core is in a range of 5 μm to 30 μm.4. The silicon-carbon-based composite negative electrode active material of claim 1 , wherein the carbon-based core has a concentration gradient in which porosity is gradually increased from a center of the core to the outer portion of the core.5. The silicon-carbon-based composite negative electrode active material of claim 4 , wherein the outer portion of ...

NEGATIVE ELECTRODE ACTIVE MATERIAL AND SECONDARY BATTERY INCLUDING THE SAME

The present invention relates to a negative electrode active material and a secondary battery including the same, and specifically, provides a negative electrode active material particle including a core, which includes a carbon-based active material and an oxygen functional group, and a shell, which surrounds the core and includes a silicon-based active material. 1. A negative electrode active material particle comprising a core , which comprises a carbon-based active material and an oxygen functional group , and a shell which surrounds the core and comprises a silicon-based active material.2. The negative electrode active material particle of claim 1 , wherein the oxygen functional group comprises one or more of a hydrophilic group and a hydrophobic group.3. The negative electrode active material particle of claim 2 , wherein the hydrophilic group comprises one or more of a hydroxyl group and a carboxyl group claim 2 , and the hydrophobic group comprises one or more of an ether group and a carbonyl group.4. The negative electrode active material particle of claim 1 , wherein the oxygen functional group is covalently bound to an outermost carbon atom of the carbon-based active material.5. The negative electrode active material particle of claim 1 , wherein the oxygen functional group is bound to about 2.0 to 4.0% of all sites of an outermost carbon atom of the carbon-based active material at which the oxygen functional group is covalently bondable.6. The negative electrode active material particles of claim 1 , further comprising a coating layer which surrounds the shell and comprises one or more of a carbon-based material and a polymer.7. The negative electrode active material particle of claim 6 , wherein the carbon-based material comprise amorphous carbon claim 6 , and the polymer comprises a conductive polymer.8. The negative electrode active material particle of claim 6 , wherein the coating layer is 1 to 50 wt % of an overall weight of the negative electrode ...

NEGATIVE ELECTRODE ACTIVE MATERIAL FOR LITHIUM SECONDARY BATTERY, METHOD OF PREPARING THE SAME, AND LITHIUM SECONDARY BATTERY INCLUDING THE SAME

The present invention relates to a negative electrode active material for a lithium secondary battery, a method of preparing the same, and a lithium secondary battery including the negative electrode active material, wherein since the negative electrode active material includes a surface-treated silicon nanoparticle and the surface-treated silicon nanoparticle includes a silicon nanoparticle and a surface treatment layer which is disposed on a surface of the silicon nanoparticle and includes crystalline SiO, the negative electrode active material may exhibit significantly improved initial efficiency characteristics as well as excellent lifetime and capacity characteristics when used in a battery. 1. A negative electrode active material for a lithium secondary battery , comprising:a surface-treated silicon nanoparticle,{'sub': '2', 'wherein the surface-treated silicon nanoparticle comprises a silicon nanoparticle and a surface treatment layer which is disposed on a surface of the silicon nanoparticle and includes crystalline SiO.'}2. The negative electrode active material for a lithium secondary battery of claim 1 ,{'sub': '2', 'wherein the crystalline SiOis included in an amount of 2 wt % to 15 wt % based on a total weight of the surface-treated silicon nanoparticle.'}3. The negative electrode active material for a lithium secondary battery of claim 1 ,{'sub': '50', 'wherein the silicon nanoparticle has an average particle diameter (D) of 150 nm or less.'}4. The negative electrode active material for a lithium secondary battery of claim 1 ,wherein the surface treatment layer has a thickness of 1 nm to 20 nm.5. The negative electrode active material for a lithium secondary battery of claim 1 , further comprising a carbon-based negative electrode active material.6. The negative electrode active material for a lithium secondary battery of claim 5 ,wherein the carbon-based negative electrode active material is included in an amount of 10 wt % to 90 wt % based on a total ...

METHOD AND DEVICE FOR CANCELLING INTER-SYMBOL INTERFERENCE IN WIRELESS COMMUNICATION SYSTEM

The present disclosure relates to a pre-5-Generation (5G) or 5G communication system to be provided for supporting higher data rates Beyond 4-Generation (4G) communication system such as Long Term Evolution (LTE). The present invention provides a method and a device for cancelling inter-symbol interference in a wireless communication system. A method for a base station in a wireless communication system can comprises the steps of: transmitting multiple synchronous signals through multiple antennas to a terminal; receiving information on a propagation delay difference among the multiple synchronous signals from the terminal; and determining signal transmission timing for each of the multiple antennas on the basis of the information on the propagation delay difference. 115-. (canceled)16. An apparatus of a base station (BS) in a wireless communication system , the apparatus comprising:at least one transceiver; andat least one processor operably coupled to the at least one transceiver,wherein the at least one processor is configured to:transmit a plurality of synchronization signals to through a plurality of antennas;receive information related to a propagation delay difference (PDD) for the plurality of synchronization signals from a terminal; andtransmit signals through the plurality of antennas by adjusting a transmission timing of at least one of the signals based on the information related to the PDD.17. The apparatus of claim 16 , wherein the information related to the PDD includes identification information for indicating a reference antenna of the plurality of antennas and information indicating a PDD between the reference antenna and at least one other of the plurality of antennas.18. The apparatus of claim 17 , and wherein the reference antenna corresponds to a synchronization signal which is received first or last at the terminal among the plurality of synchronization signals claim 17 , andwherein each of the synchronization signals corresponds to each of ...

NEGATIVE ELECTRODE ACTIVE MATERIAL, METHOD OF PREPARING THE SAME, AND LITHIUM SECONDARY BATTERY INCLUDING THE SAME

The present invention relates to a negative electrode active material, a method of preparing the same, and a lithium secondary battery including the same. In particular, the present invention relates to a composite negative electrode active material that includes: a core capable of intercalating and deintercalating lithium ions; and a plurality of coating layers comprising two or more Si layers having different densities formed on a surface of the core, and thus has enhanced stability by minimizing the formation of cracks occurring by the repetition of charging and discharging, a method of preparing the same, and a lithium secondary battery including the same and thus exhibiting enhanced lifespan characteristics. 1. A composite negative electrode active material comprising:a core capable of intercalating and deintercalating lithium ions; anda plurality of coating layers comprising two or more silicon (Si) layers having different densities formed on a surface of the core.2. The composite negative electrode active material of claim 1 , wherein the core comprises a carbon-based core or a non-carbon-based core.3. The composite negative electrode active material of claim 2 , wherein the non-carbon-based core comprises Si or a non-crystalline or crystalline Si oxide represented by SiOwhere 0 Подробнее

COMPOUNDS FOR TREATING SPINAL MUSCULAR ATROPHY

Provided herein are compounds of Formula (I): 4. The compound of claim 3 , wherein{'sub': '1', 'Ris heterocyclyl;'}{'sub': 3', '4, 'wherein, heterocyclyl is optionally substituted with one, two or three Rsubstituents and optionally, with one additional Rsubstituent; or,'}{'sub': '3', 'wherein, heterocyclyl is optionally substituted with one, two, three or four Rsubstituents; and'}{'sub': '2', 'Ris aryl or heteroaryl;'}{'sub': 6', '7, 'wherein, aryl or heteroaryl is optionally substituted with one, two or three Rsubstituents and optionally, with one additional Rsubstituent.'}5. The compound of claim 1 , wherein the form is selected from a free acid claim 1 , free base claim 1 , salt claim 1 , enantiomer claim 1 , diastereomer or tautomer thereof.6. The compound of claim 5 , wherein the salt form is a chloride claim 5 , hydrobromide claim 5 , hydrochloride claim 5 , dihydrochloride claim 5 , acetate claim 5 , trifluoroacetate or trifluoroacetic acid salt.7. The compound of claim 1 , wherein the compound is selected from the group consisting of:2-(3,4-dimethoxyphenyl)-7-(1,2,3,6-tetrahydropyridin-4-yl)-4H-pyrazino[1,2-a]pyrimidin-4-one;2-(1,3-dimethylpyrrolo[1,2-a]pyrazin-7-yl)-7-(1,2,3,6-tetrahydropyridin-4-yl)-4H-pyrazino[1,2-a]pyrimidin-4-one;2-(2-methyl-1,3-benzoxazol-6-yl)-7-(1,2,3,6-tetrahydropyridin-4-yl)-4H-pyrazino[1,2-a]pyrimidin-4-one; hydrochloride (1:1)2-(2-methyl-1,3-benzoxazol-6-yl)-7-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-4H-pyrazino[1,2-a]pyrimidin-4-one;7-(1-ethyl-1,2,3,6-tetrahydropyridin-4-yl)-2-(2-methyl-1,3-benzoxazol-6-yl)-4H-pyrazino[1,2-a]pyrimidin-4-one;2-(1,3-dimethylpyrrolo[1,2-a]pyrazin-7-yl)-7-[1-(propan-2-yl)-1,2,3,6-tetrahydropyridin-4-yl]-4H-pyrazino[1,2-a]pyrimidin-4-one;2-(4,6-dimethylpyrazolo[1,5-a]pyrazin-2-yl)-7-(piperidin-4-yl)-4H-pyrazino[1,2-a]pyrimidin-4-one;2-(4, 6-dimethylpyrazolo[1,5-a]pyrazin-2-yl)-7-(1-methylpiperidin-4-yl)-4H-pyrazino[1,2-a]pyrimidin-4-one;2-(4, 6-dimethylpyrazolo[1,5-a]pyrazin-2-yl)-7-(1- ...

SYSTEM AND METHOD FOR PROVIDING MAGNETIC BASED NAVIGATION SYSTEM IN DENTAL IMPLANT SURGERY

A system and method for providing magnetic based navigation in dental implant surgery is disclosed. According to one embodiment, a surgical navigation system comprises a custom piece that is made to fit in a patient's anatomy and comprises a first magnetic component. The surgical navigation system further comprises an instrument assembly comprising a drill bit and a second magnetic component. A processing unit receives and displays a first position and orientation data from the first magnetic component with respect to a second position and orientation data from the second magnetic component to track the movement of the first magnetic component with respect to the second magnetic component. 1. A surgical navigation system comprising:a custom piece made to fit in a patient's anatomy, the custom piece comprising a first magnetic component;an instrument assembly comprising a drill bit and a second magnetic component;a processing unit receiving at least one of a first position and orientation data from the first magnetic component and a second position and orientation data from the second magnetic component; anda display displaying the at least one of the first position and orientation data of the first magnetic component and the second position and orientation data of the second magnetic component.2. The surgical navigation system of claim 1 , wherein the first magnetic component is a magnetic transmitter claim 1 , and the second magnetic component is a magnetic sensor.3. The surgical navigation system of claim 2 , wherein the magnetic sensor receives signal transmitted from the magnetic transmitter and determines the second position and orientation data based on the received signal from the magnetic transmitter.4. The surgical navigation system of claim 1 , wherein the first magnetic component is a magnetic sensor claim 1 , and the second magnetic component is a magnetic transmitter.5. The surgical navigation system of further comprising a magnetic transmitter claim 1 ...

METHOD OF PREPARING NEGATIVE ELECTRODE ACTIVE MATERIAL

The present invention relates to a method of preparing a negative electrode active material which includes forming a mixture by mixing LiO and SiO(0 Подробнее

COMPOSITION FOR TREATING BLOOD CANCER USING 4'-THIO-5-AZA-2'-DEOXYCYTIDINE AND USES THEREOF

The present invention relates to pharmaceutical compositions for treating blood cancer, which includes 4′-thio-5-aza-2′-deoxycytidine (Aza-T-dCyd), and methods of treating blood cancer using a composition for oral administration that includes Aza-T-dCyd. The present invention provides a significant blood cancer therapeutic effect without having toxicity in a blood cancer mouse model or a human even with the Aza-T-dCyd dose conventionally known to have toxicity. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. 2. The pharmaceutical composition of claim 1 , wherein the therapeutically effective amount is of from about 5 mg/mto no more than about 10 mg/m.3. The pharmaceutical composition of claim 1 , wherein the therapeutically effective amount is of from about 35 mg/mto no more than about 55 mg/m.4. The pharmaceutical composition of claim 1 , wherein the therapeutically effective amount is of from about 55 mg/mto no more than about 66 mg/m.6. The method of claim 5 , wherein the effective amount is of from about 5 mg/mto no more than about 10 mg/mper 24 hour time period.7. The method of claim 5 , wherein the effective amount is of from about 35 mg/mto no more than about 55 mg/mper 24 hour time period.8. The method of claim 5 , wherein the effective amount is of from about 55 mg/mto no more than about 66 mg/mper 24 hour time period.9. The method of claim 5 , wherein the effective amount is administered in a single dose.10. The method of claim 5 , wherein the effective amount is administered via a plurality of doses.11. The method of claim 5 , wherein administering is repeated administration.12. The method of claim 11 , wherein administering is for a time period of from about 4 days to about 6 days.13. The method of claim 5 , wherein administering is via a course of treatment comprising:(a) a first treatment cycle that includes administering the effective amount of ...

SUBSTITUTED PYRIDINE AND PYRAZINE BMI-1 INHIBITORS

Amine substituted pyridine and pyrazine compounds and forms thereof that inhibit the function and reduce the level of B-cell specific Moloney murine leukemia virus integration site 1 (Bmi-1) protein and methods for their use to inhibit Bmi-1 function and reduce the level of Bmi-1 to treat a cancer mediated by Bmi-1 are described herein. 2. The compound of claim 1 , wherein Ris optionally substituted heteroaryl or heterocyclyl selected from 1H-pyrazolyl claim 1 , 1H-imidazolyl claim 1 , 1 claim 1 ,2-oxazolyl claim 1 , pyridinyl claim 1 , 1H-indolyl claim 1 , 2H-indazolyl claim 1 , 4 claim 1 ,5 claim 1 ,6 claim 1 ,7-tetrahydro-2H-indazolyl claim 1 , 1H-benzimidazolyl claim 1 , imidazo[2 claim 1 ,1-b][1 claim 1 ,3]thiazolyl claim 1 , pyrazolo[1 claim 1 ,5-a]pyridinyl claim 1 , pyrazolo[1 claim 1 ,5-c]pyrimidinyl claim 1 , imidazo[1 claim 1 ,2-a]pyridinyl claim 1 , 5 claim 1 ,6 claim 1 ,7 claim 1 ,8-tetrahydroimidazo[1 claim 1 ,2-a]pyridinyl claim 1 , 1H-imidazo[4 claim 1 ,5-b]pyridinyl claim 1 , 1H-imidazo[4 claim 1 ,5-c]pyridinyl claim 1 , 4 claim 1 ,5 claim 1 ,6 claim 1 ,7-tetrahydro-3H-imidazo[4 claim 1 ,5-c]pyridinyl claim 1 , imidazo[1 claim 1 ,2-a]pyrazinyl claim 1 , imidazo[1 claim 1 ,2-a]pyrimidinyl claim 1 , 7H-purinyl or quinolinyl.3. A compound or a form thereof is selected from the group consisting of:6-(1H-benzimidazol-1-yl)-N-(4-methoxyphenyl)pyrazin-2-amine6-(1H-benzimidazol-1-yl)-N-(4-iodophenyl)pyrazin-2-amineN-(3-chloro-4-methoxyphenyl)-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyridin-2-amineN-(4-methoxyphenyl)-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyridin-2-amineN-(4-methoxyphenyl)-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amine6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]-N-[4-(trifluoromethyl)phenyl]pyrazin-2-amineN-(3-fluoro-4-methoxyphenyl)-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyrazin-2-amineN-(3-fluoro-4-methoxyphenyl)-6-[2-(trifluoromethyl)imidazo[1,2-a]pyridin-3-yl]pyridin-2-amineN-(4- ...

NEGATIVE ELECTRODE ACTIVE MATERIAL, NEGATIVE ELECTRODE INCLUDING THE SAME AND LITHIUM SECONDARY BATTERY INCLUDING THE SAME

The present invention relates to a negative electrode active material which includes a secondary particle including a first particle which is a primary particle, wherein the first particle includes a first core and a first surface layer which is disposed on a surface of the first core and contains carbon, and the first core includes a metal compound which includes one or more of a metal oxide and a metal silicate and one or more of silicon and a silicon compound; a method of preparing the same; an electrode including the same; and a lithium secondary battery including the same. 1. A negative electrode active material , comprising a secondary particle including a first particle which is a primary particle and a second particle which is a primary particle ,wherein the first particle includes a first core, and a first surface layer which is disposed on a surface of the first core and contains carbon, andthe first core includes:one or more of silicon and a silicon compound; anda metal compound which includes one or more of a metal oxide and a metal silicate,wherein the secondary particle further includes a second particle which is a primary particle, the second particle includes a second core and a second surface layer which is disposed on a surface of the second core and contains carbon, and the second core includes one or more of silicon and a silicon compound.2. The negative electrode active material according to claim 1 , wherein the metal compound is doped in an amount of 1 to 50 wt % based on the total weight of the first particle.3. The negative electrode active material according to claim 1 , wherein a weight ratio of the first particle and the second particle is in a range of 1:0.25 to 1:4.4. The negative electrode active material according to claim 1 , wherein an average particle size Dof each of the first core and the second core is in a range of 0.5 to 20 μm.5. The negative electrode active material according to claim 1 , wherein the silicon included in each ...

Light transmitting and receiving device and method

The present invention relates to a light transmitting and receiving device and method, which output the power of a partial optical pulse such that the power thereof is different from that of another optical pulse, so as to receive reflected light, and identify whether an object, which is undetectable using the reflected light of an optical pulse outputted with relatively low power, is detected using the reflected light of an optical pulse outputted with relatively high power, so as to adjust the power of an optical pulse to be output thereafter. Therefore, detection efficiency can be maximized using low power while eye safety requirements are satisfied.

4'-THIO-NUCLEOTIDE AND -NUCLEOSIDE PRODRUGS FOR THE TREATMENT OF CANCER

The present disclosure is concerned with 4′-thio nucleotide and nucleoside compounds for the treatment of various cancers such as, for example, sarcomas, carcinomas, hematological cancers, solid tumors, breast cancer, cervical cancer, gastrointestinal cancer, colorectal cancer, brain cancer, skin cancer, prostate cancer, ovarian cancer, bladder cancer, thyroid cancer, testicular cancer, pancreatic cancer, endometrial cancer, melanomas, gliomas, leukemias, lymphomas, chronic myeloproliferative disorders, myelodysplastic syndromes, myeloproliferative neoplasms, and plasma cell neoplasms (myelomas). This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. 2. The compound of claim 1 , wherein Ris hydrogen.3. The compound of claim 3 , wherein Ris hydrogen.4. The compound of claim 3 , wherein Ris —C(O)R.5. The compound of claim 3 , wherein Ris —P(O)(OR).812-. (canceled)1619-. (canceled)21. (canceled)23. (canceled)2528-. (canceled)30. (canceled)32. (canceled)33. A pharmaceutical composition comprising a therapeutically effective amount of the compound of and a pharmaceutically acceptable carrier.34. A method of treating a disorder of uncontrolled cellular proliferation in a subject claim 1 , the method comprising the step of administering to the subject an effective amount of the compound of .3540-. (canceled)410. The method of claim claim 1 , wherein the disorder is a cancer.423540. The method of claim - claim 1 , wherein the cancer is selected from a sarcoma claim 1 , a carcinoma claim 1 , a hematological cancer claim 1 , a solid tumor claim 1 , breast cancer claim 1 , cervical cancer claim 1 , gastrointestinal cancer claim 1 , colorectal cancer claim 1 , brain cancer claim 1 , skin cancer claim 1 , prostate cancer claim 1 , ovarian cancer claim 1 , bladder cancer claim 1 , thyroid cancer claim 1 , testicular cancer claim 1 , pancreatic cancer claim 1 , endometrial cancer ...

SCANNING LIDAR HAVING OPTICAL STRUCTURE THAT SHARES A TRANSMISSION RECEIVING LENS

One aspect is a scanning light detection and ranging (LiDAR) having an optical structure which shares a transmitting and receiving lens. In one embodiment, the LiDAR includes a hole mirror disposed to have a first angle with respect to a horizontal surface and including a hole and a reflecting surface and a beam source configured to output a pulsed laser beam from one side of the hole mirror toward the hole. The LiDAR also includes a transmitting and receiving lens configured to generate a collimated beam to move the pulsed laser beam which passed through the hole toward a measurement target, receive a beam reflected from the measurement target, and transmit the reflected beam to the hole mirror. The LiDAR further includes a beam detector disposed to face the reflecting surface of the hole mirror and configured to receive the beam reflected from the hole mirror and convert the reflected beam into an electronic signal. 1. A scanning light detection and ranging (LiDAR) having an optical structure which shares a transmitting and receiving lens , the scanning LiDAR comprising:a hole mirror disposed to have a first angle with respect to a horizontal surface and including a hole and a reflecting surface;a beam source configured to output a pulsed laser beam from one side of the hole mirror toward the hole;a transmitting and receiving lens configured to generate a collimated beam to move the pulsed laser beam which passed through the hole toward a measurement target, receive a beam reflected from the measurement target, and transmit the reflected beam to the hole mirror; anda beam detector disposed to face the reflecting surface of the hole mirror and configured to receive the beam reflected from the hole mirror and convert the reflected into an electronic signal.28-. (canceled)9. The scanning LiDAR of claim 1 , wherein the hole mirror includes a reflecting surface on a surface facing the transmitting and receiving lens.10. The scanning LiDAR of claim 9 , wherein:the beam ...

NEGATIVE ELECTRODE ACTIVE MATERIAL, NEGATIVE ELECTRODE INCLUDING THE SAME, AND SECONDARY BATTERY INCLUDING THE NEGATIVE ELECTRODE

The present invention relates to a negative electrode active material including a carbonaceous matrix having a plurality of nano-particles, wherein the nano-particles have a silicon core, an oxide layer disposed on the silicon core and including SiO(0 Подробнее

PYRAZOLE DERIVATIVES AS TNIK, IKKe AND TBK1 INHIBITOR AND PHARMACEUTICAL COMPOSITION COMPRISING SAME

Provided is pyrazole derivatives as a TNIK (Traf2- and NCK-interacting kinase), IKKε (I-kappa-B kinase epsilon) and TBK1 (TANK-binding kinase 1) inhibitor; the pyrazole derivative according to the present invention effectively inhibits TNIK, IKKε and TBK1, and thus is useful not only as an anticancer agent for the treatment of various cancers including colorectal cancer, breast cancer, CNS cancer, colon cancer, non-small cell lung cancer, kidney cancer, prostate cancer, ovarian cancer, uterus cancer, stomach cancer, liver cancer, skin cancer, lung cancer, brain cancer, bladder cancer, esophageal cancer, pancreatic cancer, thyroid cancer, head and neck cancer, squamous cell carcinoma, osteosarcoma, B-cell or T-cell lymphoma, acute or chronic leukemia and multiple myeloma, but as a therapeutic agent for chronic inflammation. 2. The compound of claim 1 , wherein Ris substituted or unsubstituted phenyl claim 1 , pyrazole or pyridine.3. The compound of claim 2 , wherein Ris phenyl which is substituted with at least one substituent selected from the group consisting of fluoro claim 2 , methoxy claim 2 , methylthio claim 2 , methyl claim 2 , tert-butyl claim 2 , methylpiperazinyl claim 2 , piperazinyl claim 2 , morpholino claim 2 , dimethylpiperazinyl claim 2 , dimethylmorpholino claim 2 , hydroxypiperidinyl claim 2 , ethylpiperazinyl claim 2 , methoxypiperidinyl claim 2 , methoxyethylamino claim 2 , methoxypropylamino claim 2 , pyrrolidinylethylamino claim 2 , morpholinoethylamino claim 2 , dimethylaminopropylamino claim 2 , methyl(methylaminoethylamino) claim 2 , tetrahydrofuranylmethylamino claim 2 , dimethylamino ethylamino claim 2 , isopentylamino claim 2 , tetrahydropyranyl ethylamino claim 2 , hexylamino claim 2 , cyclohexylamino claim 2 , cyclopentylamino claim 2 , cycloheptylamino claim 2 , cyclooctylamino claim 2 , cyclohexylmethylamino claim 2 , cyclohexenylethylamino claim 2 , pyrrolylethylamino claim 2 , tert-butyloxy carbonyl tetrahydropyridinyl claim 2 , ...

QUARTER WAVE PLATE HAVING META-PATTERNS, METHOD OF MANUFACTURING THE QUARTER WAVE PLATE, AND DETECTION APPARATUS HAVING THE QUARTER WAVE PLATE

Provided are a quarter wave plate, a method of manufacturing the quarter wave plate, and a detection apparatus including the quarter wave plate. The quarter wave plate includes a transparent substrate, and a plurality of meta-patterns provided on the transparent substrate, wherein the plurality of meta-patterns are configured to convert linearly polarized light incident thereon into circularly polarized light. 1. A quarter wave plate comprising:a transparent substrate; anda plurality of meta-patterns provided on the transparent substrate,wherein the plurality of meta-patterns are configured to convert linearly polarized light incident thereon into circularly polarized light.2. The quarter wave plate of claim 1 , wherein the transparent substrate is flexible.3. The quarter wave plate of claim 1 , wherein the transparent substrate is inflexible.4. The quarter wave plate of claim 1 , wherein the plurality of meta-patterns comprise horizontally and vertically repeating unit meta-patterns.5. The quarter wave plate of claim 1 , wherein the transparent substrate comprises horizontally and vertically repeating unit regions claim 1 , and two meta-patterns that are different from each other are provided in each of the unit regions.6. The quarter wave plate of claim 1 , wherein the plurality of meta-patterns are coated with a protection film.7. The quarter wave plate of claim 4 , wherein each of the unit meta-patterns comprises:a first meta-pattern; anda second meta-pattern that is perpendicular to and separated from the first meta-pattern.8. The quarter wave plate of claim 7 , wherein the first meta-pattern and the second meta-pattern are embossed.9. The quarter wave plate of claim 7 , wherein a meta-material layer is provided on the transparent substrate claim 7 ,the first meta-pattern is a first hole formed in the meta-material layer, andthe second meta-pattern is a second hole formed in the meta-material layer.10. The quarter wave plate of claim 1 , wherein a wavelength ...

7-AZAINDOLE OR 4,7-DIAZAINDOLE DERIVATIVES AS IKK EPSILON AND TBK1 INHIBITOR AND PHARMACEUTICAL COMPOSITION COMPRISING SAME

Provided are 7-azaindole or 4,7-diazaindole derivatives as an IKKε (I-kappa-B kinase epsilon) and TBK1 (TANK-binding kinase 1) inhibitor. The 7-azaindole or 4,7-diazaindole derivative effectively inhibits IKKε and TBK1, and thus is useful not only as an anticancer agent for the treatment of various cancers including colorectal cancer, breast cancer, CNS cancer, colon cancer, non-small cell lung cancer, kidney cancer, prostate cancer, ovarian cancer, uterus cancer, stomach cancer, liver cancer, skin cancer, lung cancer, brain cancer, bladder cancer, esophageal cancer, pancreatic cancer, thyroid cancer, head and neck cancer, squamous cell carcinoma, osteosarcoma, B-cell or T-cell lymphoma, acute or chronic leukemia and multiple myeloma, but as a therapeutic agent for chronic inflammation. 2. The compound of claim 1 , wherein the ring A is benzene.4. The compound of claim 1 , wherein Ris H claim 1 , halogen claim 1 , substituted or unsubstituted phenyl claim 1 , substituted or unsubstituted thiophenyl claim 1 , substituted or unsubstituted isoindolinonyl claim 1 , substituted or unsubstituted pyridinyl claim 1 , substituted or unsubstituted furanyl claim 1 , substituted or unsubstituted benzodioxolyl claim 1 , substituted or unsubstituted thiadiazolyl claim 1 , substituted or unsubstituted indazolyl or substituted or unsubstituted oxoisoindolinyl5. The compound of claim 4 , wherein the phenyl claim 4 , thiophenyl claim 4 , isoindolinonyl claim 4 , pyridinyl claim 4 , furanyl claim 4 , benzodioxolyl claim 4 , thiadiazolyl claim 4 , indazolyl or oxoisoindolinyl is substituted with one or more substituents selected from the group consisting of fluoro claim 4 , chloro claim 4 , amino claim 4 , tetrahydro-2H-pyran-amino claim 4 , cyano claim 4 , acetyl claim 4 , acetamido claim 4 , methylsulfonamido claim 4 , methyl claim 4 , morpholinomethyl claim 4 , piperazinylmethyl claim 4 , methylpiperazinylmethyl claim 4 , ethylpiperazinylmethyl claim 4 , pyrrolidinylmethyl claim 4 , ...

METHOD AND DEVICE PERFORMING COMMUNICATION IN WIRELESS COMMUNICATION SYSTEM

Disclosed is a 5G or pre-5G communication system for supporting a data transmission rate higher than that of a 4G communication system such as LTE. According to one embodiment of the present invention, a method of a base station in a wireless communication system can comprise the steps of: generating a first synchronization signal; confirming symbol index information on a plurality of symbols transmitted through beams in directions different from each other; and transmitting the first synchronization signal and the symbol index information in each of the plurality of symbols. 1. A method of a base station in a wireless communication system , comprising:generating a first synchronization signal;identifying symbol index information on a plurality of symbols transmitted through beams of different directions; andtransmitting the first synchronization signal and the symbol index information in each of the plurality of symbols.2. The method of claim 1 , wherein the symbol index information is configured based on at least one bit and is transmitted through a physical broadcast channel (PBCH).3. The method of claim 1 , wherein the symbol index information is a second synchronization signal configured to distinguish the plurality of symbols claim 1 , based on a predetermined sequence.4. The method of claim 3 , wherein the second synchronization signal is an extended synchronization signal (ESS) generated based on a zadoff-chu sequence claim 3 , andwherein the first synchronization signal is a primary synchronization signal (PSS).5. A base station in a wireless communication system claim 3 , comprising:a transceiver configured to transmit and receive signals; anda controller configured to generate a first synchronization signal, to identify symbol index information on a plurality of symbols transmitted through beams of different directions, and to control the transceiver to transmit the first synchronization signal and the symbol index information in each of the plurality of ...

NEGATIVE ELECTRODE ACTIVE MATERIAL, NEGATIVE ELECTRODE INCLUDING THE NEGATIVE ELECTRODE ACTIVE MATERIAL, AND SECONDARY BATTERY INCLUDING THE NEGATIVE ELECTRODE

The present invention relates to a negative electrode active material which includes a carbonaceous matrix including a first particle and a second particle, wherein the first particle includes a silicon core, an oxide layer which is disposed on the silicon core and includes SiO(0 Подробнее

INDUSTRIAL HIGH-TEMPERATURE REFORMER AND REFORMING METHOD

An industrial high temperature reformer and the reforming method in which a temperature of the reforming furnace is maintained at 1000° C. or higher by burning the coke, and a temperature of at least an upper half of the reforming furnace is maintained at 1200° C. or higher by burning the syngas, thereby producing syngas at a capacity of 500 m/hour or more by reforming all carbonaceous feedstock which is supplied to the reforming furnace. 1. An industrial high temperature reforming method comprising:a first step of supplying coke to the reforming furnace;a second step of supplying a first oxygen to the reforming furnace, and maintaining a temperature of the reforming furnace at 1000° C. or higher by burning the coke with the first oxygen;a third step of supplying steam to the reforming furnace;a fourth step of maintaining a temperature of at least an upper half of the reforming furnace at 1200° C. or higher by burning at least one of a gas mixture and a first syngas, with a second oxygen; anda fifth step of supplying carbonaceous feedstock to the reforming furnace, and generating a second syngas by reforming the carbonaceous feedstock,wherein the gas mixture is generated through the burning of the coke and the steam, and the first syngas is supplied to the reforming furnace.2. The industrial high temperature reforming method of claim 1 , wherein the oxygen used to burn the coke at the second step is supplied via a lower section of the reforming furnace claim 1 , and the oxygen used to burn at least one of the gas mixture and the first syngas at the fourth step is supplied via a mid-section of the reforming furnace.3. The industrial high temperature reforming method of claim 1 , wherein the first syngas at the fourth step is part of the second syngas generated at the fifth step claim 1 , and the high temperature syngas generated at the fifth step pyrolyzes the carbonaceous feedstock and is then cooled.4. The industrial high temperature reforming method of claim 1 , ...

ADJUSTABLE ANATOMY DISPLAY TABLE

An adjustable anatomy display table is disclosed. According to one embodiment, the adjustable anatomy table includes a display configured to visualize the anatomy in a real size, a base configured to support the display, and an adjustable mechanism that mechanically couples the display to the base. The adjustable mechanism is configured to adjust a position of the display relative to the base. 1. An imaging system comprising:a display configured to visualize an image of an anatomy in a real size;a base configured to support the display; andan adjustable mechanism that mechanically couples the display to the base,wherein the adjustable mechanism is configured to adjust a position of the display relative to the base.2. The imaging system of claim 1 , wherein the adjustable mechanism is a tilting mechanism that is configured to tilt the display from a horizontal position to an upright position.3. The imaging system of claim 1 , wherein the adjustable mechanism is a rotational mechanism that is configured to rotate the display about a rotational axis.4. The imaging system of claim 1 , wherein the adjustable mechanism is a height adjusting mechanism that is configured to adjust a height of the display.5. The imaging system of further comprises a second adjustable mechanism that is selected from a group comprising a tilting mechanism that is configured to tilt the display from a horizontal position to an upright position claim 1 , a rotational mechanism that is configured to rotate the display about a rotational axis claim 1 , and a height adjusting mechanism that is configured to adjust a height of the display.6. The imaging system of claim 1 , wherein the anatomy is a human anatomy claim 1 , and wherein the display is configured to visualize the human anatomy from a head to a toe.7. The imaging system of claim 1 , wherein the imaging system is configured to receive an input from a user claim 1 , and wherein the input from the user comprises an input to dissect claim 1 , ...

NEGATIVE ELECTRODE ACTIVE MATERIAL, NEGATIVE ELECTRODE INCLUDING THE SAME, AND SECONDARY BATTERY INCLUDING THE NEGATIVE ELECTRODE

A negative electrode active material including a core having SiO(0≤x<2), an intermediate layer covering at least a portion of a surface of the core and including at least one of silicon nitride or silicon oxynitride, and a carbon coating layer covering at least a portion of the intermediate layer and containing nitrogen. 1. A negative electrode active material , comprising:{'sub': 'x', 'a core including SiO(0≤x<2);'}an intermediate layer covering at least a portion of a surface of the core and including at least one of silicon nitride or silicon oxynitride; anda carbon coating layer covering at least a portion of the intermediate layer and containing nitrogen.2. The negative electrode active material of claim 1 , wherein an average particle diameter (D) of the core is 0.1 μm to 100 μm.3. The negative electrode active material of claim 1 , wherein the core further comprises a metal compound claim 1 , and wherein the metal compound comprises at least one of a metal oxide or a metal silicate.4. The negative electrode active material of claim 3 , wherein the metal compound is the metal oxide and the metal oxide comprises one or two or more oxides selected from the group consisting of Li claim 3 , Mg claim 3 , Al claim 3 , Ca claim 3 , and Ti.5. The negative electrode active material of claim 3 , wherein the metal compound is the metal silicate and the metal silicate includes one or two or more silicates selected from the group consisting of Li claim 3 , Mg claim 3 , Al claim 3 , Ca claim 3 , and Ti.6. The negative electrode active material of claim 3 , wherein the metal compound is included in an amount of 1 wt % to 60 wt % based on a total weight of the core.7. The negative electrode active material of claim 1 , wherein a thickness of the intermediate layer is 1 nm to 100 nm.8. The negative electrode active material of claim 1 , wherein a thickness of the carbon coating layer is 1 nm to 100 nm.9. The negative electrode active material of claim 1 , wherein the nitrogen ...

COMPOUNDS AS TNIK, IKKEPSILON AND TBK1 INHIBITORS AND PHARMACEUTICAL COMPOSITION COMPRISING SAME

Provided is a compound of formula (I) as a TNIK (Traf2- and NCK-interacting kinase), IKKε (I-kappa-B kinase epsilon) and TBK1 (TANK-binding kinase 1) inhibitor; the compound according to the present invention effectively inhibits TNIK, IKKε and TBK1, and thus is useful not only as an anticancer agent for the treatment of various cancers including colorectal cancer, breast cancer, CNS cancer, colon cancer, non-small cell lung cancer, kidney cancer, prostate cancer, ovarian cancer, uterus cancer, stomach cancer, liver cancer, skin cancer, lung cancer, brain cancer, bladder cancer, esophageal cancer, pancreatic cancer, thyroid cancer, head and neck cancer, squamous cell carcinoma, osteosarcoma, B-cell or T-cell lymphoma, acute or chronic leukemia and multiple myeloma, but as a therapeutic agent for chronic inflammation. 2. The compound of claim 1 , wherein Ris pyrrolidine.3. The compound of claim 1 , wherein Ris —NH—C(═O)—R claim 1 , Rbeing Calkyl claim 1 , substituted or unsubstituted phenyl claim 1 , substituted or unsubstituted thiophenyl claim 1 , substituted or unsubstituted furanyl claim 1 , substituted or unsubstituted pyridinyl or substituted or unsubstituted pyrrolidinyl.4. The compound of claim 3 , wherein said phenyl claim 3 , thiophenyl claim 3 , furanyl claim 3 , pyridinyl or pyrrolidinyl is substituted with one or more substituents selected from the group consisting of fluoro claim 3 , chloro claim 3 , bromo claim 3 , nitro claim 3 , cyano claim 3 , amino claim 3 , tertbutyloxycarbonyl claim 3 , methyl claim 3 , methylthio claim 3 , methylsulfonyl claim 3 , methoxy claim 3 , acetamido claim 3 , methylpiperazinyl claim 3 , aminopiperidinyl claim 3 , morpholino claim 3 , morpholinoethoxy claim 3 , methylamino claim 3 , dimethylamino claim 3 , dimethylaminoethylamino claim 3 , dimethylaminopropylamino claim 3 , aminoethylamino claim 3 , hydroxyethylamino claim 3 , hydroxypropylamino claim 3 , hydroxybutylamino claim 3 , methoxyethylamino claim 3 , ...

NEGATIVE ELECTRODE ACTIVE MATERIAL FOR LITHIUM SECONDARY BATTERY, METHOD OF PREPARING THE SAME, AND LITHIUM SECONDARY BATTERY INCLUDING THE MATERIAL

Provided are a negative electrode active material for a lithium secondary battery and a method of preparing the same, wherein since the negative electrode active material includes porous polycrystalline silicon and the porous polycrystalline silicon includes pores disposed at grain boundaries, the negative electrode active material may exhibit a buffering action by internally absorbing changes in volume of the active material during charge and discharge. As a result, lifetime characteristics of a negative electrode and a battery may be improved. 1. A negative electrode active material for a lithium secondary battery , the negative electrode active material comprising:porous polycrystalline silicon,wherein the porous polycrystalline silicon comprises pores disposed at grain boundaries.2. The negative electrode active material for a lithium secondary battery of claim 1 , wherein the porous polycrystalline silicon further comprises pores formed on a surface of the porous polycrystalline silicon.3. The negative electrode active material for a lithium secondary battery of claim 1 , wherein the porous polycrystalline silicon has a porosity of 5 vol % to 80 vol %.4. The negative electrode active material for a lithium secondary battery of claim 1 , wherein the porous polycrystalline silicon has an average grain size of 3 nm to 300 nm.5. The negative electrode active material for a lithium secondary battery of claim 1 , wherein the porous polycrystalline silicon has an average particle diameter (D) of 0.01 μm to 50 μm.6. The negative electrode active material for a lithium secondary battery of claim 1 , wherein the porous polycrystalline silicon comprises a metal impurity in an amount of 2 claim 1 ,000 ppm or less.7. The negative electrode active material for a lithium secondary battery of claim 1 , wherein the porous polycrystalline silicon does not comprise a metal impurity.8. The negative electrode active material for a lithium secondary battery of claim 1 , further ...

NEGATIVE ELECTRODE ACTIVE MATERIAL, NEGATIVE ELECTRODE INCLUDING THE NEGATIVE ELECTRODE ACTIVE MATERIAL, AND SECONDARY BATTERY INCLUDING THE NEGATIVE ELECTRODE

A negative electrode active material which includes a core including SiO(0 Подробнее

NEGATIVE ELECTRODE ACTIVE MATERIAL, METHOD OF PREPARING THE SAME, NEGATIVE ELECTRODE INCLUDING THE SAME AND LITHIUM SECONDARY BATTERY INCLUDING THE SAME

The present invention relates to a negative electrode active material including a secondary particle in which primary particles are aggregated, wherein the primary particle includes: a core including one or more of silicon and a silicon compound; and a surface layer which is disposed on a surface of the core and contains carbon, wherein an average particle size Dof the core is in a range of 0.5 μm to 20 μm, a method of preparing the same, an electrode including the same, and a lithium secondary battery including the same. 1. A negative electrode active material , comprising a secondary particle in which primary particles are aggregated ,wherein the primary particle includes:a core including one or more of silicon and a silicon compound; anda surface layer which is disposed on a surface of the core and contains carbon,{'sub': '50', 'wherein an average particle size Dof the core is in a range of 0.5 μm to 20 μm.'}2. The negative electrode active material according to claim 1 , wherein the silicon compound is a silicon oxide (SiO claim 1 , 0 Подробнее

INTEGRATED LIGHT TRANSMISSION/RECEPTION OPTICAL SYSTEM MODULE AND SCANNING LIDAR HAVING SAME

In one embodiment, an integrated light transmission/reception optical system module includes a light receiving lens, a light source, and a light transmitting mirror. The light receiving lens receives light, concentrates the received light on a light detector disposed at a rear position, and has an optical path groove formed to be directed from a circumference to a central portion and formed to expose a front side. The light source outputs a pulse laser along the optical path groove from the circumference of the light receiving lens toward the central portion of the light receiving lens. The light transmitting mirror is disposed within the optical path groove, is located on a path of the pulse laser, and reflects in a front direction the pulse laser outputted from the light source. Other embodiments are also possible. 1. An integrated light transmission/reception optical system module comprising:a light receiving lens configured to receive light and concentrate the received light on a light detector disposed at a rear position, the light receiving lens having an optical path groove formed to be directed from a circumference to a central portion and formed to expose a front side;a light source configured to output a pulse laser along the optical path groove from the circumference of the light receiving lens toward the central portion of the light receiving lens; anda light transmitting mirror disposed within the optical path groove, located on a path of the pulse laser, and configured to reflect in a front direction the pulse laser outputted from the light source.2. The integrated light transmission/reception optical system module of claim 1 , wherein the light source is configured to output the pulse laser toward the central portion of the light receiving lens in a direction perpendicular to the light received by the light receiving lens.3. The integrated light transmission/reception optical system module of claim 2 , wherein the light transmitting mirror is disposed ...

MICRO-LED ARRAY DISPLAY DEVICES

Micro-LED array display devices are disclosed. One of the micro-LED display devices includes: a micro-LED panel including a plurality of micro-LED pixels; a CMOS backplane including a plurality of CMOS cells corresponding to the micro-LED pixels to individually drive the micro-LED pixels; and bumps electrically connecting the micro-LED pixels to the corresponding CMOS cells in a state in which the micro-LED pixels are arranged to face the CMOS cells. The micro-LED pixels are flip-chip bonded to the corresponding CMOS cells formed on the CMOS backplane through the bumps so that the micro-LED pixels are individually controlled. 114-. (canceled)15. A method for fabricating a micro-LED array display device comprising:preparing a micro-LED panel comprising a substrate and a plurality of micro-LED pixels formed on the substrate;preparing a CMOS backplane comprising a plurality of CMOS cells corresponding to the micro-LED pixels;arranging bumps electrically connecting the micro-LED pixels to the corresponding CMOS cells; andheating the bumps in a state in which the bumps is interposed between the micro-LED pixels and the CMOS cells corresponding to the micro-LED pixels;wherein the micro-LED pixels are formed by growing a first conductivity-type semiconductor layer, an active layer, and a second conductivity-type semiconductor layer in this order on the substrate and etching the layers, the micro-LED pixels have a vertical structure including the first conductivity-type semiconductor layer, the active layer, and the second conductivity-type semiconductor layer formed in this order, and the active layer and the second conductivity-type semiconductor layer are removed from the exposed portions of the first conductivity-type semiconductor layer where none of the micro-LED pixels are formed on the substrate, wherein a first conductivity-type metal layer is formed over the exposed portions of the first conductivity-type semiconductor layer and is spaced apart from the micro-LED ...

MICRO-LED ARRAY DISPLAY DEVICES

Micro-LED array display devices are disclosed. One of the micro-LED display devices includes: a micro-LED panel including a plurality of micro-LED pixels; a CMOS backplane including a plurality of CMOS cells corresponding to the micro-LED pixels to individually drive the micro-LED pixels; and bumps electrically connecting the micro-LED pixels to the corresponding CMOS cells in a state in which the micro-LED pixels are arranged to face the CMOS cells. The micro-LED pixels are flip-chip bonded to the corresponding CMOS cells formed on the CMOS backplane through the bumps so that the micro-LED pixels are individually controlled. 114-. (canceled)15. A micro-LED array display device comprising:a micro-LED panel comprising a plurality of micro-LED pixels;a CMOS backplane comprising a plurality of CMOS cells corresponding to the micro-LED pixels;bumps electrically connecting the micro-LED pixels to the corresponding CMOS cells in a state in which the micro-LED pixels are arranged to face the CMOS cells; anda first conductivity-type metal layer formed along the periphery of the micro-LED panel,wherein the micro-LED pixels are flip-bonded to the corresponding CMOS cells formed on the CMOS backplane through the bumps so that the micro-LED pixels are individually controlled.16. The micro-LED array display device according to claim 15 , wherein the micro-LED pixels are formed by growing a first conductivity-type semiconductor layer claim 15 , an active layer claim 15 , and a second conductivity-type semiconductor layer in this order on a substrate and etching the layers claim 15 , the micro-LED pixels have a vertical structure comprising the first conductivity-type semiconductor layer claim 15 , the active layer claim 15 , and the second conductivity-type semiconductor layer formed in this order claim 15 , and the active layer and the second conductivity-type semiconductor layer are removed from the exposed portions of the first conductivity-type semiconductor layer where none ...

Polymer

The present application relates to a polymer and a use thereof. The present application may provide a functional polymer which expresses a low solubility to a polar solvent and a non-polar solvent and which is suitable for forming a film. If applied to the use of cosmetics such as mascara or to medical uses, the polymer in the present application may express a tolerance to diverse solvents such as sebum, sweat, tears and the like, and thus enables makeup to last, etc. Accordingly, the polymer may be applied to diverse uses and used in film forming agents, cosmetic compositions, or cosmetics, or the like.

NEGATIVE ELECTRODE ACTIVE MATERIAL, NEGATIVE ELECTRODE INCLUDING THE SAME AND LITHIUM SECONDARY BATTERY INCLUDING THE SAME

The present invention relates to a negative electrode active material which includes a secondary particle including a first particle which is a primary particle, wherein the first particle includes a first core and a first surface layer which is disposed on a surface of the first core and contains carbon, and the first core includes a metal compound which includes one or more of a metal oxide and a metal silicate and one or more of silicon and a silicon compound; a method of preparing the same; an electrode including the same; and a lithium secondary battery including the same. 1. A negative electrode active material , comprising a secondary particle including a first , particle which is a primary particle ,wherein, the first particle includes a first core, and a first surface layer which is disposed on a surface of the first core and contains carbon, andthe first core includes:one or more of silicon and a silicon compound; anda metal compound which includes one or more of a metal oxide and a metal silicate.2. The negative electrode active material according to claim 1 , wherein the metal compound is doped in an amount of 1 to 50 wt % based on the total weight of the first particle.3. The negative electrode active material according claim 1 , to claim 1 , wherein the secondary particle flintier includes a second particle which is a primary particle claim 1 , the second particle includes a second core and a second surface layer which is disposed on a surface of the second core and contains carbon claim 1 , and the second core includes one or more of silicon and a silicon compound.4. The negative electrode active material according to claim 3 , wherein a weight ratio of the first particle and the second particle is in a range of 1:0.25 to 1:4.5. The negative electrode active material according to claim 3 , wherein an average particle size Dof each of the first core and the second core is in a range of 0.5 to 20 μm.6. The negative electrode active material according to ...

NOVEL ANTI-MESOTHELIN ANTIBODY AND COMPOSITION COMPRISING THE SAME

The present invention relates to an antibody specifically bound to mesothelin (MSLN), a nucleic acid encoding the antibody, a vector and a host cell including the nucleic acid, a method for producing the antibody, and a pharmaceutical composition for treating cancer or tumor including the antibody as an active ingredient. The antibody specifically bound to the mesothelin according to the present invention has high affinity and specificity to an antigen, such that it is possible to develop an antibody effectively usable for treatment or diagnosis of cancer or tumor diseases. 1. An antibody binding to mesothelin comprising a heavy chain variable region comprising a heavy chain CDR comprising:a heavy chain CDR1 comprising an amino acid sequence of SEQ ID NO: 9, 15, 21, 27, or 59;a heavy chain CDR2 comprising an amino acid sequence of SEQ ID NO: 10, 16, 22, 28, 60, 65, 71, 75, 80, 84, 121, 122, 123 or 125; anda heavy chain CDR3 comprising an amino acid sequence of SEQ ID NO: 11, 17, 23, 29, 61, 66, 72, 76, 81, 85, 124 or 126.2. An antibody binding to mesothelin comprising a light chain variable region comprising a light chain CDR comprising:a light chain CDR1 comprising an amino acid sequence of SEQ ID NO: 12, 18, 24, 30, 62, 67, 70, 77, 86 or 117;a light chain CDR2 comprising an amino acid sequence of SEQ ID NO: 13, 19, 25, 63, 68, 73, 78 or 82; anda light chain CDR3 comprising an amino acid sequence of SEQ ID NO: 14, 20, 26, 64, 69, 74, 79, 83, 87, 118, 119 or 120.3. The antibody of claim 1 , wherein the heavy chain variable region comprises an amino acid sequence of SEQ ID NO: 1 claim 1 , 3 claim 1 , 5 claim 1 , 7 claim 1 , 46 claim 1 , 48 claim 1 , 51 claim 1 , 53 claim 1 , 55 claim 1 , 57 claim 1 , 112 claim 1 , 113 claim 1 , 114 claim 1 , 115 or 116 claim 1 , or an amino acid sequence having a sequence homology thereto of at least 80%.4. The antibody of claim 1 , wherein the light chain variable region comprises an amino acid sequence of SEQ ID NO: 2 claim 1 , 4 ...

NOVEL ANTI-GLYPICAN 3 ANTIBODY AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME

The present invention relates to an antibody specifically binding to glypican 3 (GPC3), a nucleic acid encoding the antibody, a vector and a host cell containing the nucleic acid, a method of preparing the antibody, and a pharmaceutical composition for treating cancer or tumor, containing the antibody as an active ingredient. The antibody specifically binding to glypican 3 according to the present invention may be effectively used to treat cancer or tumor, particularly, hepatocellular carcinoma due to high affinity and specificity to glypican 3. 1. An anti-glypican 3 antibody comprising a heavy chain variable region comprising the following heavy chain CDRs:a heavy chain CDR1 comprising an amino acid sequence of SEQ ID NO: 133, 143, 149, 159, 169, 174, 184, 199, 262, 268, 273, 281, 285, 291, 297, 308, 353, 363, 374, 380, or 386;a heavy chain CDR2 comprising an amino acid sequence of SEQ ID NO:134, 144, 150, 160, 170, 175, 185, 200, 231, 263, 266, 269, 274, 282, 286, 292, 298, 303, 309, 314, 318, 323, 328, 331, 336, 341, 345, 349, 354, 359, 364, 369, 375, 381, or 387; anda heavy chain CDR3 comprising an amino acid sequence of SEQ ID NO: 135, 139, 145, 151, 155, 161, 165, 171, 176, 180, 186, 189, 194, 195, 201, 205, 207, 210, 214, 218, 222, 227, 232, 237, 239, 243, 247, 250, 254, 258, 259, 264, 267, 270, 275, 278, 279, 283, 287, 293, 299, 304, 310, 315, 319, 324, 329, 332, 337, 342, 346, 350, 355, 360, 365, 370, 376, 382, or 388, ora light chain variable region comprising the following light chain CDRs:a light chain CDR1 comprising an amino acid sequence of SEQ ID NO: 136, 140, 146, 152, 156, 162, 166, 172, 177, 181, 187, 190, 193, 196, 202, 208, 211, 215, 219, 223, 224, 228, 233, 240, 244, 251, 255, 260, 265, 271, 288, 294, 300, 305, 311, 316, 320, 325, 333, 338, 343, 347, 356, 361, 366, 371, 377, 383, or 389;a light chain CDR2 comprising an amino acid sequence of SEQ ID NO: 137, 141, 147, 153, 157, 163, 167, 178, 182, 191, 197, 203, 209, 212, 216, 220, 225, 229, 234 ...

Antibody-linker-drug conjugate, preparation method therefor, and anticancer drug composition containing same

The present invention relates to an antibody-linker-drug conjugate in which an antibody and a cytotoxic drug are conjugated through an enzyme cleavable peptide linker capable of directly binding to a lysine residue of an antibody, a preparation method therefor, and an anticancer drug composition containing the same as an active ingredient.

NEGATIVE ELECTRODE ACTIVE MATERIAL, NEGATIVE ELECTRODE INCLUDING THE SAME, AND SECONDARY BATTERY INCLUDING THE NEGATIVE ELECTRODE

The present invention relates to a negative electrode active material including a spherical carbon-based particle, and a carbon layer disposed on the spherical carbon-based particle and including a nano-particle, wherein the nano-particle has a silicon core, an oxide layer disposed on the silicon core and including SiO(0 Подробнее

DISPLAY DEVICE AND CONTROLLING METHOD OF DISPLAY DEVICE

A display device and a method capable of rotating a display based on a type of a user command are provided. The display device according to the disclosure receives a user command while first content is displayed on the display, the display being configured to operate in a first orientation while displaying the first content, maintains the display to operate in the first orientation when the received user command is a command to control a feature corresponding to the first content, determines, based on a type of a second content, to control the display to operate in the first orientation or a second orientation different from the first orientation when the received user command is a command to display the second content on the display, and controls the motor to rotate the display based on the determined first orientation or the second orientation. 1. A display device comprising:a display;a motor configured to rotate the display;a communicator configured to receive a user command from at least one of an external user terminal device or an external remote control device;a memory configured to store at least one instruction; and receive the user command while first content is displayed on the display, the display being configured to operate in a first orientation while displaying the first content,', 'identify whether the received user command is to control a feature corresponding to the first content,', 'based on identifying that the received user command is a command to control a feature corresponding to the first content, maintain the display to operate in the first orientation,', 'based on identifying that the received user command is a command to display the second content on the display, determine, based on a type of a second content, to control the display to operate in the first orientation or a second orientation different from the first orientation, and, 'a processor configured to execute the at least one instruction tocontrol the motor to rotate the display ...

VIRTUAL FLYING CAMERA SYSTEM

A virtual flying camera system is disclosed. According to one embodiment, a system includes: a video buffer configured to store input video streams from a plurality of cameras; and a video processor configured to generate an output video stream from the input video streams. The input video streams include a plurality of input video frames, each of the plurality of input video frames includes at least a partial image of a moving target. The output video stream includes a plurality of output video frames, each of the plurality of output video frames is generated by shifting a corresponding input video stream to position the moving target at a desired location within the output video frame, The output video stream is playable at a user-adjustable speed showing a view of a virtually flying camera that follows the moving target at the desired location within each of the plurality of output video frames. 1. A system comprising:a video buffer configured to store input video streams from a plurality of cameras; anda video processor configured to generate an output video stream from the input video streams,wherein the input video streams comprise a plurality of input video frames, each of the plurality of input video frames includes at least a partial image of a moving target, wherein the output video stream comprises a plurality of output video frames, each of the plurality of output video frames is generated by shifting a corresponding input video stream to position the moving target at a desired location within the output video frame, andwherein the output video stream is playable at a user-adjustable speed showing a view of a virtually flying camera that follows the moving target at the desired location within each of the plurality of output video frames.2. The system of claim 1 , wherein at least some of the plurality of input video frames include a reference object that has a known distance from the plurality of cameras claim 1 , and wherein the video processor ...

SILICON-BASED PARTICLE-POLYMER COMPOSITE AND NEGATIVE ELECTRODE ACTIVE MATERIAL COMPRISING THE SAME

The present invention relates to a silicon-based particle-polymer composite, which includes silicon-based particles; and a polymer coating layer formed on the silicon-based particles, in which the polymer coating layer includes metal-substituted poly(acrylic acid) in which hydrogen atoms in carboxyl groups of the poly(acrylic acid) chain are substituted with one or more selected from the group consisting of K, Na and Li. 1. A silicon-based particle-polymer composite , comprising:silicon-based particles; anda polymer coating layer formed on the silicon-based particles,wherein the polymer coating layer comprises a metal-substituted poly(acrylic acid) in which hydrogen atoms of carboxyl groups are substituted with one or more selected from the group consisting of K, Na and Li.2. The composite according to claim 1 , wherein 10 to 100% of the hydrogen atoms are substituted with K claim 1 , Na or Li.3. The composite according to claim 1 , wherein the polymer coating layer comprises the metal-substituted poly(acrylic acid) in which the hydrogen atoms are substituted with Na.4. The composite according to claim 1 , wherein the polymer coating layer comprises the metal-substituted poly(acrylic acid) in which 50 to 100% of the hydrogen atoms are substituted with Na.5. The composite according to claim 1 , wherein the polymer coating layer comprises the metal-substituted poly(acrylic acid) in which 70 to 90% of the hydrogen atoms are substituted with Na.6. The composite according to claim 1 , wherein the silicon-based particles comprise a mixture of one or more selected from the group consisting of Si claim 1 , silicon oxide particles (SiO claim 1 , 0 Подробнее

COMPOUNDS FOR TREATING SPINAL MUSCULAR ATROPHY

Provided herein are compounds, compositions thereof and uses therewith for treating spinal muscular atrophy. 115-. (canceled)17. The method of claim 16 , wherein Ris heteroaryl selected from furo[3 claim 16 ,2-b]pyridinyl claim 16 , furo[3 claim 16 ,2-c]pyridinyl claim 16 , furo[2 claim 16 ,3-c]pyridinyl claim 16 , thieno[3 claim 16 ,2-c]pyridinyl claim 16 , thieno[2 claim 16 ,3-d]pyrimidinyl claim 16 , 1H-pyrrolo[2 claim 16 ,3-b]pyridinyl claim 16 , 1H-pyrrolo[2 claim 16 ,3-c]pyridinyl claim 16 , pyrrolo[1 claim 16 ,2-a]pyrimidinyl claim 16 , pyrrolo[1 claim 16 ,2-a]pyrazinyl claim 16 , pyrrolo[1 claim 16 ,2-b]pyridazinyl claim 16 , pyrazolo[1 claim 16 ,5-a]pyridinyl claim 16 , pyrazolo[1 claim 16 ,5-a]pyrazinyl claim 16 , imidazo[1 claim 16 ,2-a]pyridinyl claim 16 , imidazo[1 claim 16 ,2-a]pyrimidinyl claim 16 , imidazo[1 claim 16 ,2-c]pyrimidinyl claim 16 , imidazo[1 claim 16 ,2-b]pyridazinyl claim 16 , imidazo[1 claim 16 ,2-a]pyrazinyl claim 16 , imidazo[2 claim 16 ,1-b][1 claim 16 ,3]thiazolyl claim 16 , imidazo[2 claim 16 ,1-b][1 claim 16 ,3 claim 16 ,4]thiadiazolyl claim 16 , [1 claim 16 ,3]oxazolo[4 claim 16 ,5-b]pyridinyl and quinoxalinyl; wherein claim 16 , each instance of heteroaryl is optionally substituted with one claim 16 , two or three Rsubstituents and optionally claim 16 , with one additional Rsubstituent.18. The method of claim 16 , wherein Ris Calkyl selected from methyl claim 16 , ethyl claim 16 , propyl claim 16 , isopropyl and tert-butyl.19. The method of claim 16 , wherein Ris Calkyl selected from methyl claim 16 , ethyl claim 16 , propyl claim 16 , isopropyl and tert-butyl.20. The method of claim 16 , wherein Ris claim 16 , in each instance claim 16 , hydrogen.21. The method of claim 16 , wherein Ris Calkyl.22. The method of claim 16 , wherein Ris hydrogen or Calkyl.23. The method of claim 16 , wherein the salt form is a chloride claim 16 , hydrobromide claim 16 , hydrochloride claim 16 , dihydrochloride claim 16 , acetate claim 16 , ...

METHOD FOR PRODUCING DIPHENYLMETHANE DERIVATIVE

The present invention relates to an improved method for producing a diphenylmethane derivative which is effective as a sodium-dependent glucose cotransporter (SGLT) inhibitor, the method being carried out by means of a convergent synthesis method in which each major group is separately synthesized and then coupled. As such, in comparison to a linear synthesis method disclosed in existing documents, the synthesis pathway is compact and yield can be increased, and risk factors inherent in the linear synthesis pathway can be reduced. Furthermore, the crystal form of the compound produced according to the method has superb physicochemical characteristics, and thus can be effectively utilized in fields such as pharmaceutical manufacturing. 3. The method for producing the compound of Formula 1a according to claim 2 ,wherein the cyclization reaction is a cyclization reaction using a Vilsmeier reagent, a cyclization reaction using a leaving group, a cyclization reaction using a halide, or a cyclization reaction using a Mitsunobu reaction.6. The method for producing the compound of Formula 1a according to claim 1 ,{'sub': '1-7', 'wherein the method further comprises an alkylation reaction after the step (3), and X′ is Calkyl.'}7. The method for producing the compound of Formula 1a according to claim 1 ,wherein the step (3) further includes isolating only a compound in which glucose is in a β-form, after or during the deprotection and reduction process.11. The method for producing the compound of Formula 1a according to claim 9 , wherein each of the compound of Formula 7 and n-butyllithium is used in an amount of 1.5 to 2.5 equivalents with respect to 1 equivalent of the compound of Formula 6.12. The method for producing the compound of Formula 1a according to claim 1 ,wherein the method further comprises a step of performing crystallization using a solvent selected from the group consisting of toluene, ethyl acetate, dichloromethane, a mixture of tetrahydrofuran and ...

Mixed supported metallocene catalyst, method of preparing the same, method of preparing polyolefin using the mixed supported metallocene catalyst, and polyolefin prepared using the method of preparing polyolefin using the mixed supported metallocene cata

スイッチドキャパシタアレイ

(57)【要約】 【課題】 金属相互接続及び誘電体酸化物段階上の金属 オーバーラップのためのキャパシタ上部プレートの寄生 が最小化できるスイッチドキャパシタアレイを提供す る。 【解決手段】 ２進加重されたキャパシタアレイは、充 電分布型アナログ／ディジタル又は、ディジタル／アナ ログ変換器、スイッチドキャパシタフィルタ等に使用さ れる。このキャパシタは、一列に所定の間隔を置いて配 列される。このような１列のキャパシタアレイは、各々 の相互接続金属ラインが一定の長さを有するようにスイ ッチアレイと並列に配列される。この所定の距離を置い たレイアウトは、金属相互接続及び誘電体酸化物段階上 の金属オーバーラップのための上部プレート寄生エラー だけではなく、酸化物厚さ傾斜及びエッジ解像力エラー を完全に除去する。

modified conjugated diene-based polymer and rubber composition including the same

a presente invenção se refere a um polímero à base de dieno conjugado modificado e, mais particularmente, a um polímero à base de dieno conjugado modificado tendo uma forma unimodal de curva de distribuição de peso molecular em cromatografia de permeação em gel (gpc), distribuição de peso molecular (pdi; mwd) menor do que 1,7 e um teor de si de 100 ppm ou mais com base no peso, e incluindo uma unidade de repetição derivada de um monômero vinílico aromático em uma quantidade de 30% em peso ou mais, e uma composição de borracha incluindo a mesma. The present invention relates to a modified conjugated diene-based polymer and more particularly to a modified conjugated diene-based polymer having a unimodal molecular weight distribution (gpc) chromatography distribution curve. molecular weight (pdi; mwd) of less than 1.7 and a bios content of 100 ppm or more based on weight, and including a repeating unit derived from an aromatic vinylic monomer in an amount of 30% by weight or more, and a rubber composition including the same.

Process for preparing polysilane by catalytic dehydrogenative condensation of organosilane and metal complex catalyst therefor

A polysilane is produced by subjecting a trihydrosilane to hydrogenative condensation in the presence of a titanium or zirconim complex catalyst having a first group selected from a dialkylaminoalkylcyclopentadienyl group, an α-[(dialkylamino)alkyl]indenyl group and a β-[(dialkylamino)alkyl]indenyl group and a second group selected from a cyclopentadienyl group and a pentamethylcyclopentadienyl group. The above dialkylaminoalkyl group may be replaced by a branched alkyl group. The zirconium complexes are novel compounds.

イソチアゾロン無水物の製造方法

(57)【要約】 【課題】 廃棄物をほとんど発生させないとともに工程 条件が良好で安定性が卓越し、作業性の向上によって生 産性及び経済性を向上させることができるイソチアゾロ ン無水溶液を提供する。 【解決手段】 イソチアゾロンを含有する水溶液をハロ ゲン化炭化水素またはニトロ化炭化水素を使用して抽出 した後、有機層を分離してからハロゲン化炭化水素また はニトロ化炭化水素を除去してイソチアゾロン無水物を 製造し、この無水物にグリコール、アルコール、グリコ ールエーテル類等の有機溶媒を混合して、安定性が向上 したイソチアゾロン無水溶液を製造する。