15-09-2016 дата публикации
Номер: US20160267650A1
Принадлежит:
Systems and methods are provided the autocentering, autofocusing, acquiring, decoding, aligning, analyzing and exchanging among various parties, images, where the images are of arrays of signals associated with ligand-receptor interactions, and more particularly, ligand-receptor interactions where a multitude of receptors are associated with microparticles or microbeads. The beads are encoded to indicate the identity of the receptor attached, and therefore, an assay image and decoding image are aligned to effect the decoding. The images or data extracted from such images can be exchanged between de-centralized assay locations and a centralized location where the data are analyzed to indicate assay results. Access to data can be restricted to authorized parties in possession of certain encoding information, so as to preserve confidentiality. 1conducting an assay on a patient sample by contacting a uniquely encoded array of receptors with the patient sample and determining if the patient sample comprises any ligands that interact with the receptors by analyzing an assay image for optical signatures that are associated with receptor-ligand interactions, wherein the array is decoded at a location other than the location at which the assay is conducted.. A method of conducting an assay and analyzing results therefrom at separate locations, comprising: This application is a continuation of U.S. patent application Ser. No. 13/084,869, filed Apr. 12, 2011, which is a continuation of U.S. patent application Ser. No. 11/439,599, filed May 23, 2006, now issued as U.S. Pat. No. 7,940,968, which is a continuation of U.S. patent application Ser. No. 10/714,203, filed Nov. 14, 2003, now issued as U.S. Pat. No. 7,526,114, which claims priority to U.S. Provisional Application No. 60/426,839, filed Nov. 15, 2002. All of the applications and patents cited above are hereby incorporated by reference in their entireties.Recent rapid advances in molecular biology have created more demand ...
Подробнее