METHOD AND DEVICE FOR HEATING FUEL FOR INTERNAL COMBUSTION ENGINE

PROCESS Of CALIBRATION Of a SYSTEM OF MEASUREMENT OF QUANTITY Of AIR ADMITTED IN a THERMAL ENGINE

METHOD FOR ESTIMATING THE ENCLOSED MASS OF GASES DURING EACH OPERATING CYCLE IN THE COMBUSTION CHAMBER OF A CYLINDER OF AN INTERNAL COMBUSTION ENGINE

METHOD FOR ESTIMATING THE ENCLOSED MASS OF GASES DURING EACH OPERATING CYCLE IN THE COMBUSTION CHAMBER OF A CYLINDER OF AN INTERNAL COMBUSTION ENGINE

METHOD FOR ESTIMATING THE ENCLOSED MASS OF GASES DURING EACH OPERATING CYCLE IN THE COMBUSTION CHAMBER OF A CYLINDER OF AN INTERNAL COMBUSTION ENGINE

METHOD FOR ESTIMATING THE ENCLOSED MASS OF GASES DURING EACH OPERATING CYCLE IN THE COMBUSTION CHAMBER OF A CYLINDER OF AN INTERNAL COMBUSTION ENGINE

METHOD FOR ESTIMATING THE ENCLOSED MASS OF GASES DURING EACH OPERATING CYCLE IN THE COMBUSTION CHAMBER OF A CYLINDER OF AN INTERNAL COMBUSTION ENGINE

METHOD FOR ESTIMATING THE ENCLOSED MASS OF GASES DURING EACH OPERATING CYCLE IN THE COMBUSTION CHAMBER OF A CYLINDER OF AN INTERNAL COMBUSTION ENGINE

PROCEEDED OF DETECTION Of a LOSS OF COMBUSTION AND APPLICATION TO the ORDERING Of an ENGINE HAS VARIABLE COMPRESSION RATIO (VCR)

SYSTEM AND METHOD FOR OPERATING A HYBRID POWERTRAIN.

Système de commande d'un groupe motopropulseur hybride d'un véhicule automobile comprenant un moteur à combustion interne (2), un moteur électrique (3) et une batterie, comprenant un moyen de détermination (7) de la répartition d'une requête de couple entre le moteur électrique (4) et le moteur à combustion interne (2), la répartition étant déterminée en fonction de la requête de couple du conducteur, une estimation de l'état de charge de la batterie, et une estimation de l'état du système de traitement des gaz d'échappement, et un moyen de détermination (8) de consignes d'émissions sonores et de rejets d'oxydes d'azote du moteur à combustion interne (2), en fonction d'une estimation de la vitesse du véhicule, de la consigne de couple et de la consigne de vitesse de rotation du moteur à combustion interne (2), d'une valeur limite d'émissions sonores et d'une valeur limite de rejets d'oxydes d'azote dans les gaz d'échappement.

Method for managing common rail injection system of e.g. direct injection diesel engine of car, involves determining control signal of injection circuit, and transmitting signal towards pressurization unit to control pressure of circuit

Un procédé de gestion d'un système d'injection d'un moteur comprenant un circuit d'alimentation, un circuit d'injection comprenant des moyens de pressurisation du carburant et des moyens d'injection, et un circuit de retour agencé de façon à récupérer du carburant issu du circuit d'injection et à réinjecter au moins une partie du carburant récupéré en amont de ce circuit d'injection, le procédé comprenant : recevoir (202) une valeur mesurée de température (Tcarb(n)), déterminer (204, 205, 206, 207, 208) un signal de commande de circuit d'injection (Prail_cor(n)) en fonction d'un point de fonctionnement du moteur souhaité (pos_acc, vm), en fonction de la valeur de température reçue, et en fonction d'une valeur de température souhaitée, et transmettre (210) le signal de commande vers les moyens de pressurisation afin de contrôler la pression du circuit d'injection.

INSTALLATION AND METHOD OF INSTALLING A LOCKING STATION IN A STORAGE SYSTEM OF A CYCLE

METHOD FOR ESTIMATING THE ENCLOSED MASS OF GASES DURING EACH OPERATING CYCLE IN THE COMBUSTION CHAMBER OF A CYLINDER OF AN INTERNAL COMBUSTION ENGINE

METHOD FOR ESTIMATING THE ENCLOSED MASS OF GASES DURING EACH OPERATING CYCLE IN THE COMBUSTION CHAMBER OF A CYLINDER OF AN INTERNAL COMBUSTION ENGINE

METHOD FOR ESTIMATING THE ENCLOSED MASS OF GASES DURING EACH OPERATING CYCLE IN THE COMBUSTION CHAMBER OF A CYLINDER OF AN INTERNAL COMBUSTION ENGINE

METHOD FOR ESTIMATING THE ENCLOSED MASS OF GASES DURING EACH OPERATING CYCLE IN THE COMBUSTION CHAMBER OF A CYLINDER OF AN INTERNAL COMBUSTION ENGINE

METHOD FOR CONTROLLING A VALVE FOR REGULATING A FLOW OF A COOLING LIQUID THE RECIRCULATION GASES OF AN INTERNAL COMBUSTION ENGINE

FLOATING SUPPORT COMPRISING A FLOAT AND A DAMPING PLATE PROVIDED WITH AN ARRAY OF ORIFICES

PROCEEDED OF CORRECTION Of WAVES OF PRESSURE IN a SYSTEM Of INJECTION Of an INTERNAL COMBUSTION ENGINE OF DIESEL TYPE.

THE EXHAUST SYSTEM OF AN INTERNAL COMBUSTION ENGINE AND INTERNAL COMBUSTION ENGINE WITH SUCH AN EXHAUST LINE

MOTEUR A COMBUSTION INTERNE COMPORTANT UN DISPOSITIF DE DEPOLLUTION DES OXYDES D'AZOTE ET PROCEDE DE COMMANDE

Un moteur thermique (10) à combustion interne comporte un système de dépollution (13, 14) qui comprend un dispositif de traitement des oxydes d'azote (14). On commande le moteur (10) dans un premier mode de fonctionnement dans lequel le taux d'émission des oxydes d'azote est supérieur à un seuil prédéterminé lorsque le dispositif de traitement des oxydes d'azote (14) est en mesure de traiter les oxydes d'azote, et sinon dans un deuxième mode de fonctionnement dans lequel les émissions d'oxydes d'azote par le moteur sont inférieures au seuil prédéterminé.

PROCESS Of ESTIMATE OF the ETHANOL RATE Of a FUEL

FLOATING SUPPORT COMPRISING A FLOAT AND A DAMPING PLATE PROVIDED WITH AN ARRAY OF ORIFICES

La présente invention concerne un support flottant (1) muni d'un flotteur principal (2) et d'une plaque d'amortissement (3). La plaque d'amortissement (3) comporte une unique rangée d'orifices (4), sensiblement parallèle à la périphérie de la plaque d'amortissement.

THE EXHAUST SYSTEM OF AN INTERNAL COMBUSTION ENGINE AND INTERNAL COMBUSTION ENGINE WITH SUCH AN EXHAUST LINE

Une ligne d'échappement de gaz brûlés pour moteur (4) à combustion interne comprend une turbine (11) d'un turbocompresseur (9), une turbine (22) d'un système de turbo-récupération (1) disposée à l'aval de la turbine (11) du turbocompresseur (9) dans la ligne d'échappement, et un élément de jonction (24) permettant le branchement d'une ligne de recirculation des gaz brûlés et disposé entre la turbine (11) du turbocompresseur (9) et la turbine (22) du système de turbo-récupération (1), La ligne d'échappement comprend également un dispositif de post-traitement (14) interposé entre la turbine (11) du turbocompresseur (9) et l'élément de jonction (24). Un moteur à combustion interne comprenant une telle ligne d'échappement est également décrit.

POSITIONING DEVICE OF AN AIRBAG

La présente invention a pour objet un dispositif de positionnement d'un airbag caractérisé en ce qu'il comprend : - un module (1) comportant un boitier (3) et intégrant au moins un coussin gonflable, - un logement (2) destiné à recevoir le module, caractérisé en ce que le boitier (3) du module (1) comporte au moins une patte (5) destinée à être insérée dans un orifice (6) adapté du logement (2), le logement (2) comprenant un cadre (7) de forme adaptée pour : - entourer le boitier (3) du module (1) équipé d'au moins une patte (5) lors de l'encastrement du module (1) dans le logement (2) selon un premier axe, et - insérer au moins une patte (5) du boitier (3) du module (1) dans son orifice (6) adapté par translation du boitier (3) du module (1) selon un second axe différent du premier axe.

FLOATING SUPPORT COMPRISING A FLOAT AND A DAMPER PLATE WITH VARIABLE SECTION WITH DEPTH

La présente invention concerne un support flottant (1) muni d'un flotteur principal (2) et d'une plaque d'amortissement (3). La plaque d'amortissement (3) comporte une section variable avec la profondeur. De plus, la plaque d'amortissement (3) a une section horizontale minimale Sd1 supérieure à la section horizontale Sc du flotteur principal (2).

METHOD FOR ESTIMATING THE ENCLOSED MASS OF GASES DURING EACH OPERATING CYCLE IN THE COMBUSTION CHAMBER OF A CYLINDER OF AN INTERNAL COMBUSTION ENGINE

METHOD FOR ESTIMATING THE ENCLOSED MASS OF GASES DURING EACH OPERATING CYCLE IN THE COMBUSTION CHAMBER OF A CYLINDER OF AN INTERNAL COMBUSTION ENGINE

METHOD FOR ESTIMATING THE ENCLOSED MASS OF GASES DURING EACH OPERATING CYCLE IN THE COMBUSTION CHAMBER OF A CYLINDER OF AN INTERNAL COMBUSTION ENGINE

METHOD FOR ESTIMATING THE ENCLOSED MASS OF GASES DURING EACH OPERATING CYCLE IN THE COMBUSTION CHAMBER OF A CYLINDER OF AN INTERNAL COMBUSTION ENGINE

METHOD FOR ESTIMATING THE ENCLOSED MASS OF GASES DURING EACH OPERATING CYCLE IN THE COMBUSTION CHAMBER OF A CYLINDER OF AN INTERNAL COMBUSTION ENGINE

METHOD FOR ESTIMATING THE ENCLOSED MASS OF GASES DURING EACH OPERATING CYCLE IN THE COMBUSTION CHAMBER OF A CYLINDER OF AN INTERNAL COMBUSTION ENGINE

METHOD FOR ESTIMATING THE ENCLOSED MASS OF GASES DURING EACH OPERATING CYCLE IN THE COMBUSTION CHAMBER OF A CYLINDER OF AN INTERNAL COMBUSTION ENGINE

METHOD FOR ESTIMATING THE ENCLOSED MASS OF GASES DURING EACH OPERATING CYCLE IN THE COMBUSTION CHAMBER OF A CYLINDER OF AN INTERNAL COMBUSTION ENGINE

METHOD FOR ESTIMATING THE ENCLOSED MASS OF GASES DURING EACH OPERATING CYCLE IN THE COMBUSTION CHAMBER OF A CYLINDER OF AN INTERNAL COMBUSTION ENGINE

SYSTEM AND PROCESS OF ORDERING Of an INTERNAL COMBUSTION ENGINE

METHOD AND DEVICE FOR HEATING FUEL FOR INTERNAL COMBUSTION ENGINE

Procédé de réchauffage du carburant au démarrage d'un moteur thermique (1) de véhicule dans lequel la température du carburant (T_GO) et la température extérieure du véhicule (T_ext) sont comparées à un premier seuil (T_GO_lim1) en dessous duquel le démarrage du véhicule est interdit, et à un second seuil (T_GO_lim2) supérieur au premier au-dessus duquel le moteur démarre sans réchauffage du carburant, caractérisé en ce que le carburant est réchauffé par échange thermique avec le circuit de refroidissement (8) de la batterie (6) du véhicule lorsque la température extérieure (T ext) est comprise entre les deux seuils (T_GO_lim1, T_GO_lim2).

PROCESS OF CALIBRATION OF the OFFSET Of a SIGNAL RESULTING From a PRESSURE PICK-UP IN a COMBUSTION CHAMBER

PROCEEDED OF DETERMINATION Of an OUTBREAK OF COMBUSTION IN an INTERNAL COMBUSTION ENGINE

SYSTEM OF LOCKING Of a FIRST TREE COMPARED TO a SECOND TREE REMOVING the PLAYS BETWEEN THE AFOREMENTIONED TREES

DEVICE FOR DETECTION IN REAL-TIME OF THE BEGINNING OF THE PHASE OF COMBUSTION AND CORRESPONDING PROCESS

HYDROCHLORIC ACID PURIFICATION

SYSTEM AND METHOD FOR CONTROLLING THE COMBUSTION IN AN INTERNAL COMBUSTION ENGINE.

THE EXHAUST SYSTEM OF AN INTERNAL COMBUSTION ENGINE

METHOD FOR MANAGING THE OPERATION OF A HEAT ENGINE OF A HYBRID VEHICLE

HYDROCHLORIC ACID PURIFICATION

La présente invention concerne un procédé de traitement d'un flux gazeux contenant de l'acide chlorhydrique, de l'acide fluorhydrique, un composé fluoré d'intérêt et des composés organiques halogénés, dans lequel le flux gazeux est successivement soumis à : (a) une étape de lavage par une solution acide pour obtenir un flux gazeux lavé ; (b) une étape d'absorption adiabatique dans une solution aqueuse de l'acide chlorhydrique contenu dans ledit flux gazeux lavé, permettant de collecter une solution d'acide chlorhydrique ; (c) une étape d'adsorption sur charbon actif des impuretés présentes dans ladite solution d'acide chlorhydrique, pour obtenir une solution d'acide chlorhydrique purifiée et un flux gazeux renfermant ledit composé fluoré d'intérêt ; et (d) une étape de mise en contact de ladite solution d'acide chlorhydrique purifiée avec un gel de silice. Elle se rapporte également à une installation pour la mise en œuvre de ce procédé, ainsi qu'à un procédé de préparation d'un composé ...

METHOD FOR ESTIMATING THE ENCLOSED MASS OF GASES DURING EACH OPERATING CYCLE IN THE COMBUSTION CHAMBER OF A CYLINDER OF AN INTERNAL COMBUSTION ENGINE

METHOD FOR ESTIMATING THE ENCLOSED MASS OF GASES DURING EACH OPERATING CYCLE IN THE COMBUSTION CHAMBER OF A CYLINDER OF AN INTERNAL COMBUSTION ENGINE

Method for controlling diesel engine of vehicle, involves calculating stability value of indicated mean pressure within combustion chamber, and comparing stability value with threshold value to order and control metal spark plug operation

L'invention propose un procédé de commande d'un moteur thermique diesel comportant au moins une chambre de combustion à l'intérieur de laquelle sont agencés un capteur de pression et une bougie de préchauffage de ladite chambre de combustion, dont la température courante (T) et la durée d'activation sont susceptibles d'être pilotées notamment au cours d'une phase (ET1) de post-chauffage postérieure au démarrage du moteur, caractérisé en ce qu'il comporte au cours de la phase de post-chauffage (POSTCHAUFF) au moins une étape (ET1) comprenant une sous-étape (SET1) au cours de laquelle on de laquelle on calcule une valeur (S_PMI) dite de stabilité de la pression moyenne indiquée puis au moins une sous-étape (SET2) au cours de laquelle on la compare à au moins une valeur (C1, C2) de seuil déterminée pour commander et contrôler le fonctionnement de ladite bougie de préchauffage.

SYSTEM AND METHOD FOR PARKING MANAGEMENT

PROCESS Of ESTIMATE AND OUTPUT CONTROL OF COMBUSTION

METHOD AND SYSTEM FOR MONITORING THE QUALITY OF AN AGENT FOR THE SELECTIVE CATALYTIC REDUCTION OF NITROGEN OXIDES, INJECTED INTO AN EXHAUST LINE OF A MOTOR VEHICLE

METHOD FOR CONTROLLING A VALVE FOR CONTROLLING A FLOW OF A COOLING LIQUID RECIRCULATION GASES OF AN INTERNAL COMBUSTION ENGINE

L'invention concerne un procédé de pilotage d'une vanne de régulation (35) d'un débit de liquide de refroidissement circulant dans un circuit de refroidissement (30) d'une ligne de recirculation (20) d'un moteur à combustion interne (1). Selon l'invention, le procédé de pilotage comprend des étapes consistant à : a) acquérir la température dudit liquide de refroidissement, b) déterminer, en fonction de la température acquise à l'étape a), une consigne de pilotage de ladite vanne de régulation dans une position stable choisie parmi au moins trois positions stables, et c) piloter la vanne de régulation selon la consigne de pilotage déterminée à l'étape b).

TUBULAR THREADED JOINT TIGHT TO LIQUIDS AND GASES

PROCESS OF ORDERING Of an ENGINE ALLOWING an IMPROVEMENT Of a DIAGNOSIS OF COMBUSTION OF the ENGINE

PROCEEDED OF ORDERING Of an ENGINE OF VEHICLE AIMING AT DETERMINING the GAS ENFERMEE MASS IN a COMBUSTION CHAMBER

METHOD FOR MANAGING THE OPERATION OF A HEAT ENGINE OF A HYBRID VEHICLE

L'invention se rapporte à un procédé de gestion du fonctionnement d'un moteur thermique (2) d'un véhicule hybride lors d'une demande de couple, ledit moteur (2) étant suralimenté au moyen d'un turbocompresseur (11) dont au moins la turbine (14) ou le compresseur (12) est à géométrie variable et comprend des ailettes (16) orientables et aptes à être déplacées entre une position d'ouverture pour laquelle elles favorisent le passage des gaz et une position de fermeture pour laquelle elles offrent une résistance maximale auxdits gaz. La principale caractéristique d'un procédé de gestion selon l'invention, est qu'il comprend les étapes suivantes, - une étape de demande (22) de couple par le conducteur et que le moteur électrique (15) n'est pas en mesure de fournir à lui tout seul, - une étape de manœuvre (24) des ailettes au moyen d'un dispositif de commande (19) pour les placer dans une position de fermeture, dès que ladite demande de couple a été initiée, - une étape de démarrage (26) du moteur ...

Fuel quantity correcting system for direct or indirect injection type diesel engine of motor vehicle, has controller whose database has cartographic quantity compared with real quantity to correct real quantity when quantities are different

La présente invention concerne un système de correction (3) de la quantité de carburant pour l'injection tardive participant au couple d'un moteur comportant au moins une chambre de combustion (20) équipée d'un capteur de pression (4) des gaz et un vilebrequin (23) équipé d'un capteur d'angle (5). Le système de correction (3) comporte un calculateur (30) relié au capteur de pression (4) et au capteur d'angle (5) pour calculer un Couple Moyen Instantané (CMI1, CMI2) pour un cycle de combustion du moteur sans injection tardive et avec injection tardive puis à comparer ces deux Couples (CM11, CM12) pour déterminer la quantité réellement injectée de carburant pour l'injection tardive participant au couple du moteur. Cette quantité réellement injectée est ensuite comparée à une quantité cartographiée dans une banque de données du calculateur (30) pour corriger ou non la quantité cartographiée, la correction s'effectuant via une boucle de correction (340) lorsque les quantités réellement injectée ...

ESTIMATION AND REGULATION OF AT LEAST ONE OUTPUT PARAMETER OF AN INTERNAL COMBUSTION ENGINE.

HINGE FOR AIRBAG FLAP

La présente invention a pour objet une charnière pour volet (1) d'airbag réalisant la jonction entre une partie d'un tableau de bord (4) et un volet (1), caractérisé en ce que cette charnière comprend deux éléments : - un premier élément structurellement souple (2) pour réaliser un pivotement du volet (1) par rapport au tableau de bord (4) autour d'un premier axe, - un second élément structurellement rigide (3) formé par au moins deux portions réunies par une portion déformable pour réaliser un pivotement du volet (1) par rapport au tableau de bord (4) autour d'un second axe.

HOLLOW POSTS

ELEMENT OF INTERIOR TRIMMING INTEGRATING AT LEAST A SHUTTER FOR A INFLATABLE CUSHION AND CONVEYS COMPRISING SUCH AN ELEMENT.

METHOD FOR ESTIMATING THE ENCLOSED MASS OF GASES DURING EACH OPERATING CYCLE IN THE COMBUSTION CHAMBER OF A CYLINDER OF AN INTERNAL COMBUSTION ENGINE

PROCESS AND DEVICE TO CONSIDER the PRESSURE REIGNING IN the INTAKE MANIFOLD Of an INTERNAL COMBUSTION ENGINE

METHOD FOR ESTIMATING THE ENCLOSED MASS OF GASES DURING EACH OPERATING CYCLE IN THE COMBUSTION CHAMBER OF A CYLINDER OF AN INTERNAL COMBUSTION ENGINE

PROCESS OF RETIMING Of INJECTORS Of an ENGINE AND MOTOR VEHICLE IMPLEMENTING IT

METHOD FOR ESTIMATING THE ENCLOSED MASS OF GASES DURING EACH OPERATING CYCLE IN THE COMBUSTION CHAMBER OF A CYLINDER OF AN INTERNAL COMBUSTION ENGINE

DETERMINATION Of an OUTBREAK OF COMBUSTION IN an INTERNAL COMBUSTION ENGINE

FOLDABLE LIGHT SIGN

THE EXHAUST SYSTEM OF AN INTERNAL COMBUSTION ENGINE

L'invention concerne une ligne d'échappement (80) de gaz brûlés pour moteur à combustion interne (1), comportant : - un convertisseur catalytique (85), - un moyen d'acquisition (90) de la température (T) des gaz brûlés, - des moyens d'amorçage (84, 91) qui sont adaptés à favoriser la montée en température du convertisseur catalytique au démarrage du moteur à combustion interne et qui sont pilotables entre un état activé et un état désactivé, et - une unité de pilotage (100) des moyens d'amorçage à l'état activé ou désactivé, en fonction de la température acquise par ledit moyen d'acquisition. Selon l'invention, lesdits moyens d'amorçage comportent : - un système de récupération (95, 96) qui, à l'état activé, est adapté à convertir une partie de l'énergie cinétique et/ou thermique des gaz brûlés en énergie électrique, et - un système électrique de chauffage (84) desdits gaz brûlés, qui est situé en amont dudit convertisseur catalytique et qui, à l'état activé, est alimenté au moins en partie ...

DEVICE AND METHOD FOR CHARACTERIZING AN INTERFACE STRUCTURE

La présente invention concerne un dispositif de caractérisation (1) d'une interface d'une structure (6), ladite structure (6) comportant un premier matériau solide et un deuxième matériau séparés par ladite interface. Le dispositif (1) comprend : - un moyen (2) pour générer une première onde mécanique, - un moyen (2) de formation d'oscillations Brillouin, - un moyen (10) de détection de l'évolution temporelle des oscillations Brillouin, - un moyen (12) pour identifier, à partir de l'évolution temporelle des oscillations Brillouin, une réflexion de ladite première onde mécanique par ladite interface ou une transmission par ladite interface d'une deuxième onde mécanique interférant avec la première onde mécanique, et - un moyen (13) pour déterminer la variation d'amplitude des oscillations Brillouin avant et après la réflexion ou la transmission par ladite interface. L'invention concerne également un procédé de caractérisation correspondant.

METHOD OF PRODUCTION AND PURIFICATION OF THE 2, 3, 3, 3 A-SULFONATED-A 1 A-PROPEN

La présente invention concerne un procédé de purification du 2,3,3,3-tétrafluoro-1-propène (1234yf) à partir d'une première composition comprenant du 2,3,3,3-tétrafluoro-1-propène, 1,1,1,2,2-pentafluoropropane (245cb) et trans-1,3,3,3-tetrafluoro-1-propene (1234ze-E), ledit procédé comprenant les étapes de (a) mise en contact de ladite première composition avec au moins un agent d'extraction organique pour former une seconde composition ; (b) distillation extractive de ladite seconde composition pour former une troisième composition comprenant ledit agent d'extraction organique et trans-1,3,3,3-tetrafluoro-1-propene (1234ze-E); et un courant comprenant le 2,3,3,3-tétrafluoro-1-propène et le 1,1,1,2,2-pentafluoropropane (245cb), (c) récupération et séparation de ladite troisième composition pour former un courant comprenant ledit agent d'extraction organique et un courant comprenant le trans-1,3,3,3-tetrafluoro -1-propene (1234ze-E). L'invention concerne aussi un procédé de production du ...

METHOD FOR ESTIMATING THE ENCLOSED MASS OF GASES DURING EACH OPERATING CYCLE IN THE COMBUSTION CHAMBER OF A CYLINDER OF AN INTERNAL COMBUSTION ENGINE

PROCESS OF ORDERING Of a DIESEL THERMAL ENGINE AND an ASSOCIATED PREHEATING PLUG

DYNAMIC DEVICE Of IMMERSION OF PROBES AND/OR SENSORS MEASURING PARAMETERS PHYSIO-CHIMIQUES OF LIQUIDS

PROCESS OF ORDERING Of an ENGINE INCLUDING/UNDERSTANDING a STAGE AMELIOREE OF DETECTION OF the BEGINNING Of a COMBUSTION.

Method for limiting fuel pressure in e.g. common rail direct diesel injection system of vehicle, involves controlling amount of fuel injected to chamber to avoid creation of engine torque so as to evacuate excess fuel from injection system

Un procédé de limitation de la pression de carburant dans un système d'injection moteur, comprenant une étape de commande de l'injection (25) d'une quantité (Q1) de carburant dans au moins une chambre de combustion de façon à éviter la création de couple moteur.

HINGE FOR AIRBAG FLAP

La présente invention a pour objet une charnière pour volet (1) d'airbag réalisant la jonction entre une partie d'un tableau de bord (4) et un volet (1), caractérisé en ce que cette charnière comprend deux éléments : - un premier élément structurellement souple (2) pour réaliser un pivotement du volet (1) par rapport au tableau de bord (4) autour d'un premier axe, - un second élément structurellement rigide (3) formé par au moins deux portions réunies par une portion déformable pour réaliser un pivotement du volet (1) par rapport au tableau de bord (4) autour d'un second axe.

METHOD FOR ESTIMATING THE ENCLOSED MASS OF GASES DURING EACH OPERATING CYCLE IN THE COMBUSTION CHAMBER OF A CYLINDER OF AN INTERNAL COMBUSTION ENGINE

Compositions Produced Using Enteric Pathogens and Methods of Use

The present invention provides compositions including polypeptides having the characteristics of polypeptides expressed by a reference microbe such E. coli or Salmonella . Examples of Salmonella strains that can be used include, for instance, S. enterica serovar Newport, S. enterica serovar Enteritidis, S. enterica serovar Typhimurium, and S. enterica serovar Dublin. Also provided are compositions including polypeptides having a particular molecular weight and a mass fingerprint that includes polypeptide fragments having a particular set of masses, or polypeptides having an amino acid sequence with at least about 95% identity with an amino acid sequence, wherein the polypeptide has seroreactive activity. The present invention also provides methods of making and methods of using such compositions.

System and method for dynamically configurable deep brain stimulation

A DBS system and method for predicting future neurological activity in a subject and administering a corrective electrical stimulation signal to prevent anticipated pathological neuronal activity. The DBS system includes an implantable electrode configured to both record neuronal activity from a target brain area in a subject and administer the corrective electric stimulation signal to the target area. The DBS system also includes a controller configured to determine the characteristics of the corrective electrical stimulation signal based on point process models of healthy and pathological neuronal activity in the target area.

RADIOLOCATION USING PATH LOSS DATA

Determining the location of a station in a wireless network including determining path losses between the wireless station of unknown location and at least some access points at known locations. The determining includes receiving measurements from the wireless station of unknown location, and measuring the received signal strengths as a result of respective transmissions from at least some of access points at known respective transmit powers and known or determined locations to obtained measured path losses. The method further includes determining a location for the wireless station using the measured path losses and a calibrated path loss model. 1. A method comprising:receiving in a processing apparatus measurements from a particular wireless station of an unknown location, the measurements indicative of the received signal strengths at the particular wireless station resulting from transmissions at known respective transmit powers from at least some stations of a set of wireless stations; anddetermining by the processing apparatus of a location for the particular wireless station using the received measurements and a calibrated path loss model.2. A method as recited in claim 1 , further comprising:calibrating a radio loss model using data indicative of path losses between pairs of wireless stations of the set of wireless stations to determine the calibrated path loss model.3. A method as recited in claim 2 , wherein the calibrating includes comparing the path loss to the measured path loss for the known locations of the transmitting and receiving wireless stations to provide a sparse set of adjustment factors between a sparse set of known locations.4. A method as recited in claim 3 , wherein the adjustment factor between a known location and an unknown location is determined as a weighted sum of path losses between the known location and a sparse set of other known locations.5. A method as recited in claim 2 , wherein the first set of wireless stations is a set of ...

Clutch actuation assembly with satellite pistons

A dual clutch actuation assembly includes a housing, an annular central piston, a plurality of satellite pistons, and an annular apply member. The housing includes an inner cylindrical wall, an outer cylindrical wall, and a plurality of satellite cylindrical walls. The inner and outer walls define an inner piston annulus and the satellite walls define a plurality of satellite piston bores. Each of the satellite walls is disposed at least partially radially outward of the outer wall. The central piston is disposed in the inner piston annulus and is in sliding engagement with the inner and outer walls of the housing. The satellite pistons are disposed in the satellite piston bores and are in sliding engagement with the satellite walls of the housing. The apply member is axially engaged with each of the satellite pistons and includes an annular plate portion disposed radially outward of the outer cylindrical wall of the housing.

Selectable one-way clutch with breakaway feature

A selectable overrunning clutch and breakaway, i.e., energy absorbing, cone clutch is disposed in series between two elements of a planetary gear automatic transmission. An annular piston is received within a complementary cylinder and includes a male cone clutch member that mates with a stationary female cone clutch member. Also carried by the annular piston is an annular drive ring which engages a planetary gear assembly element such as a ring gear. Disposed between the drive ring and the piston is a selection ring having a plurality of circumferential apertures or ports that receive a like plurality of struts. The face of the annular piston includes pockets or recesses that receive the struts and the face of the drive ring includes notches or surfaces against which the struts engage. Tangentially disposed in the annular piston is a small selection piston which rotates the selection ring between two positions to either allow overrunning in one direction between the annular piston and the annular drive ring or lock the two components together.

CENTRIFUGALLY BALANCED HYDRAULIC CLUTCH ASSEMBLY

A centrifugally balanced hydraulic clutch assembly includes a hydraulic chamber configured to rotate about an axis of rotation and a clutch piston that is partially situated within the hydraulic chamber and defines both an apply volume and a release volume. The clutch piston includes an inner surface and an outer surface, where a portion of the outer surface faces the apply volume and defines an apply area, and a portion of the inner surface faces the release volume and defines a release area. Additionally each portion of the apply area is provided at a respective distance from the axis of rotation, and, for each portion of the apply area, there is a corresponding portion of the release area provided at the same radial distance. 1. A centrifugally balanced hydraulic clutch assembly comprising:a hydraulic chamber configured to rotate about an axis of rotation;a clutch piston partially situated within the hydraulic chamber and defining an apply volume and a release volume;the clutch piston including an inner surface and an outer surface, where a portion of the outer surface faces the apply volume and defines an apply area, and a portion of the inner surface faces the release volume and defines a release area; andwherein each portion of the apply area is provided at a respective distance from the axis of rotation, and, for each portion of the apply area, there is a corresponding portion of the release area provided at the same radial distance.2. The assembly of claim 1 , wherein the apply area extends to an extreme radial dimension that is substantially aligned with an extreme radial dimension of the release area.3. The assembly of claim 1 , wherein the clutch piston includes an inflection feature.4. The assembly of claim 3 , wherein the clutch piston includes a seal adjacent the outer surface claim 3 , the seal configured to define a boundary of the apply volume.5. The assembly of claim 4 , wherein a portion of the inner surface of the clutch piston is aligned with a ...

TORQUE TRANSMITTING ASSEMBLY WITH DOG CLUTCH AND PLATE CLUTCH FEATURES

A torque transmitting assembly for selectively transmitting torque between a first member and a second member includes a plate clutch interconnected between the first member and the second member, the plate clutch having a maximum torque capacity limited to enabling full throttle single-transition up-shifts in the transmission when the plate clutch is fully engaged. A dog clutch is connected to the first member and selectively connected to the second member. The dog clutch is in frictional engagement with the plate clutch when the plate clutch is engaged, and the dog clutch is connected to the second member prior to the transmitted torque exceeding the maximum torque capacity of the plate clutch. 1. A torque transmitting device for selectively transmitting torque between a first member and a second member in a transmission of a motor vehicle , the torque transmitting device comprising:a plate clutch interconnected between the first member and the second member, the plate clutch having a maximum torque capacity limited to enabling full throttle single-transition up-shifts in the transmission when the plate clutch is fully engaged; anda dog clutch connected to the first member and selectively connected to the second member, the dog clutch in frictional engagement with the plate clutch when the plate clutch is engaged, and wherein the dog clutch is connected to the second member prior to the transmitted torque exceeding the maximum torque capacity of the plate clutch.2. The torque transmitting device of further comprising a piston hydraulically translatable to contact the plate clutch in order to engage the plate clutch and the dog clutch.3. The torque transmitting device of wherein the plate clutch includes a reaction disc slidably connected to a support and a friction disc slidably connected to the second member claim 2 , wherein the support is supported by the piston and the dog clutch.4. The torque transmitting device of wherein the dog clutch is in frictional ...

POLYPEPTIDES AND IMMUNIZING COMPOSITIONS CONTAINING GRAM POSITIVE POLYPEPTIDES AND METHODS OF USE

The present invention provides isolated polypeptides isolatable from a spp. Also provided by the present invention are compostions that include one or more of the polypeptides, and methods for making and methods for using the polypeptides. 129-. (canceled)30Staphylococcus. A method of isolating a metal-regulated polypeptide from cells , the method comprising:{'i': 'Staphylococcus', 'growing the cells in a medium that comprises 2,2′-dipyridyl at a concentration of at least about 800 μM under conditions effective for the cell to express at least one metal-regulated polypeptide; and'}isolating the at least one metal-regulated polypeptide from the cells.31. (canceled)32. The method of wherein the medium comprises the 2 claim 30 ,2′-dipyridyl at a concentration of about 1000 μM.3337-. (canceled)38. The method of wherein the metal-regulated polypeptide is an exogenous polypeptide.39. The method of wherein the medium comprises the 2 claim 30 ,2′-dipyridyl at a concentration of about 300 μg/mL.40. A method of isolating a metal-regulated polypeptide from cells claim 30 , the method comprising:growing a seed stock of cells;transferring at least a portion of the seed stock to a culture comprising a chelator at a concentration of at least about 300 μg/mL, thereby forming a working seed;growing the working seed under conditions effective for the cells to express at least one metal regulated polypeptide; andisolating the metal-regulated polypeptide from cells of the working seed.41. The method of wherein transferring at least a portion of the seed stock to a culture comprising a chelator at a concentration of at least about 300 μg/mL comprises serially subculturing cells in medium comprising increasing concentrations of chelator.42. The method of wherein transferring at least a portion of the seed stock to a culture comprising a chelator at a concentration of at least about 300 μg/mL comprises:transferring at least a portion of the seed stock to a first subculture comprising a ...

CLUTCH AND GEAR ARRANGEMENT FOR A FRONT WHEEL DRIVE VEHICLE

A front wheel drive transmission is provided having an input member, an output member, four planetary gear sets, a plurality of coupling members and a plurality of torque transmitting devices. Each of the planetary gear sets includes a sun gear member, a planet carrier member, and a ring gear member. The torque transmitting devices include clutches and a brake arranged within a transmission housing. Each of the clutches and the brake are located within specific areas defined by the planetary gear sets and the housing walls. 1. A transaxle comprising:a transmission input member;a transmission output member;a housing having a first wall, a second wall, and a third wall extending between the first and second walls;a first, second, third and fourth planetary gear sets disposed within the housing, wherein the fourth planetary gear set is adjacent the first wall, the third planetary gear set is adjacent second wall, the first planetary gear set is adjacent the fourth planetary gear set and the second planetary gear set is between the first and third planetary gear sets, each planetary gear set having a sun gear member, a ring gear member, and a planet carrier member supporting a plurality of planet gears each configured to intermesh with both the sun gear member and the ring gear member, and wherein the ring gear member of the first planetary gear set is permanently coupled to the sun gear member of the fourth planetary gear set, the sun gear member of the first planetary gear set is permanently coupled to the sun gear member of the second planetary gear set, the planet carrier member of the second planetary gear set is permanently coupled to the ring gear member of the third planetary gear set, the planet carrier member of the third planetary gear set is permanently coupled to the planet carrier member of the fourth planetary gear set, the transmission output member is permanently coupled with the carrier members of the third and fourth planetary gear sets, and the ...

INTEGRATED OIL ROUTING SLEEVE AND TORQUE SENSOR

A torque sensor system for a transmission and other powertrain components in a motor vehicle includes a receiver and a transmitter. The receiver is operable to induce and detect a signal from the transmitter that is indicative of a torque load on the transmitter. The receiver is cylindrical and has an outer surface with a maximum, constant diameter. The outer surface defines one or more fluid transfer grooves and a docking port for an electrical connection. The fluid transfer groove and the docking port do not extend beyond the maximum outer diameter of the outer surface. Therefore, the receiver is capable of being press-fit within a component and is capable of routing fluid flow. 1. An apparatus for measuring torque on a shaft , the apparatus comprising:a tubular member having a receiver and an outer surface, the outer surface having a first end wall, a second end wall, and a pair of side walls that extend into the receiver to define a channel; anda transmitter coupled to the shaft, andwherein a current is supplied to the receiver thereby magnetizing the transmitter, and wherein as stress due to torque is applied to the shaft and therefore the transmitter the receiver detects a magnetic field from the transmitter that is proportional to the torque applied to the shaft.2. The apparatus of wherein the receiver includes a sensing circuit.3. The apparatus of wherein the channel is configured to receive and communicate a fluid.4. The apparatus of wherein the tubular member is made of a polymer and the receiver is substantially surrounded by the polymer.5. The apparatus of wherein the transmitter includes at least one magnetoelastic ring.6. The apparatus of wherein the tubular member includes a first open end and a second open end opposite the first open end.7. An assembly comprising:a first member having an inner surface that defines a bore along an axis, wherein the first member has a first fluid port that communicates a fluid to the bore and a second fluid port that ...

Immunizing Compositions and Methods of Use

The present invention provides compositions including siderophore receptor polypeptides and porins from gram negative microbes, and preferably, lipopolysaccarhide at a concentration of no greater than about 10.0 endotoxin units per milliliter. The present invention also provides methods of making and methods of using such compositions. 1. A composition comprising:at least two siderophore receptor polypeptides (SRPs) isolated from a gram negative microbe;at least two porins isolated from the gram negative microbe; andlipopolysaccharide (LPS) at a concentration of no greater than about 10.0 endotoxin units per milliliter (EU/ml).271-. (canceled)72. An antibody composition that specifically binds at least one siderophore receptor polypeptide (SRP) , the composition prepared by a method comprising:collecting a body fluid from an animal that comprises antibody that specifically binds to at least one SRP, wherein the animal has been administered an effective amount of a composition comprising at least two siderophore receptor polypeptides (SRPs) isolated from a gram positive microbe.73. The antibody composition of wherein the composition administered to the animal further comprises lipopolycassharide (LPS) at a concentration of no greater than about 10.0 EU/ml.74. The antibody composition of further comprising a pharmaceutically acceptable carrier.75. The antibody composition of wherein the gram positive microbe is an enteropathogen.76. The antibody composition of wherein the gram positive microbe is a member of the family Micrococcaceae claim 72 , family Deinococcaceae claim 72 , family Bacillaceae claim 72 , family Clostridiaceae claim 72 , family Corynebateriaceae claim 72 , family Erysipelotrichidae claim 72 , family Listeriaceae claim 72 , or family Mycobateriaceae.77Staphylococcus. The antibody composition of wherein the member of the family Micrococcaceae is spp.78Streptococcus. The antibody composition of wherein the member of the family Deinococcaceae is spp. ...

Immunizing Compositions and Methods of Use

The present invention provides compositions including siderophore receptor polypeptides and porins from gram negative microbes, and preferably, lipopolysaccarhide at a concentration of no greater than about 10.0 endotoxin units per milliliter. The present invention also provides methods of making and methods of using such compositions. 1. A composition comprising:at least two siderophore receptor polypeptides (SRPs) isolated from a gram negative microbe;at least two porins isolated from the gram negative microbe; andlipopolysaccharide (LPS) at a concentration of no greater than about 10.0 endotoxin units per milliliter (EU/ml).271-. (canceled)72. An antibody composition that specifically binds at least one siderophore receptor polypeptide (SRP) , the composition prepared by a method comprising:collecting a body fluid from an animal that comprises antibody that specifically binds to at least one SRP, wherein the animal has been administered an effective amount of a composition comprising at least two siderophore receptor polypeptides (SRPs) isolated from a gram negative microbe.73. The antibody composition of wherein the composition administered to the animal further comprises lipopolysaccharide (LPS) at a concentration of no greater than about 10.0 EU/ml.74. The antibody composition of further comprising a pharmaceutically acceptable carrier.75. The antibody composition of wherein the gram negative microbe is an enteropathogen.76. The antibody composition of wherein the gram negative microbe is a member of the family Enterobacteriaceae claim 72 , family Vibrionaceae claim 72 , family Pasteurellaceae claim 72 , or family Pseudomonadaceae.77ShigellaProteusKlebsiellaSerratiaYersinia. The antibody composition of wherein the member of the family Enterobacteriaceae is spp. claim 76 , spp. claim 76 , spp. claim 76 , spp. claim 76 , or spp.78Vibrio cholerae.. The antibody composition of wherein the member of the family Vibrionaceae is79Pasturella. The antibody composition ...

MULTI-SPEED TRANSMISSION

A transmission is provided having an input member, an output member, four planetary gear sets, a plurality of coupling members and a plurality of torque transmitting devices. Each of the planetary gear sets includes first, second and third members. The torque transmitting devices may include clutches and brakes. 1. A transmission comprising:an input member;an output member;a first and a second planetary gear set each having a first, a second, and a third member, wherein each of the first, second, and third members is included in one of a first rotary member, a second rotary member, a third rotary member, and a fourth rotary member, and wherein two of the members of the first planetary gear set are continuously separately connected with two of the members of the second planetary gear set to form two of the first, second, third, and fourth rotary members;a third and a fourth planetary gear set each having a first, a second, and a third member, wherein each of the first, second, and third members is included in one of a fifth rotary member, a sixth rotary member, a seventh rotary member, and an eighth rotary member, and wherein two of the members of the third planetary gear set are continuously separately connected with two of the members of the fourth planetary gear set to form two of the fifth, sixth, seventh, and eighth rotary members;a first transfer chain continuously connected with the third rotary member and the eighth rotary member;a second transfer chain continuously connected with the first rotary member; andsix torque transmitting devices each selectively engageable to connect at least one of the first, second, third, fourth, fifth, sixth, seventh, and eighth rotary members with at least one other of a stationary member, the first and second members of the first and second co-planar gear sets, and the first, second, third, fourth, fifth, sixth, seventh, and eight rotary members, andwherein the torque transmitting devices are selectively engageable in ...

TRANSMISSION WITH DUAL CLUTCH ACTUATION ASSEMBLY

A vehicle transmission includes an input member, an output member, a plurality of gear sets, first and second clutches, first and second actuators, and first and second bearings. The plurality of gear sets is disposed between the input member and the output member. The first and second clutches are selectively engaged to rotationally couple first and second pairs of the plurality of gear sets. The first and second actuators each have a stationary cylinder bore and a piston disposed in the stationary cylinder bore, where the pistons are substantially rotationally stationary. The first bearing is disposed between the first clutch and the nonrotating piston of the first actuator and the second bearing is disposed between the second clutch and the nonrotating piston of the second actuator. 1. A vehicle transmission comprising:an input member;an output member;a plurality of gear sets disposed between the input member and the output member;a first clutch selectively engaged to rotationally couple a first pair of the plurality of gear sets;a first actuator having a stationary cylinder bore and a piston disposed in the stationary cylinder bore, wherein the piston is substantially rotationally stationary;a first bearing disposed between the first clutch and the nonrotating piston of the first actuator;a second clutch selectively engaged to rotationally couple a second pair of the plurality of gear sets;a second actuator having a stationary cylinder bore and a nonrotating piston disposed in the stationary cylinder bore, wherein the piston is substantially rotationally stationary; anda second bearing disposed between the second clutch and the nonrotating piston of the second actuator.2. The vehicle transmission of wherein the first actuator and the second actuator are axially separated and at least partially aligned in a radial direction.3. The vehicle transmission of wherein a diameter of the nonrotating piston of the first actuator is substantially the same as a diameter of ...

Campylobacter Polypeptides and Methods of Use

The present invention provides isolated metal regulated polypeptides obtainable from a spp., and compositions including the polypeptides. The present invention also includes methods for using the compositions disclosed herein, including methods for treating in infection in a subject, for treating a condition caused by a spp., and for decreasing colonization of an animal. 1CampylobacterCampylobacterCampylobacter. An isolated metal regulated polypeptide obtainable from a spp. , wherein the polypeptide is expressed by a spp. at a detectable level during growth under low metal conditions and is not expressed by the spp. at a detectable level during growth in high metal conditions.227.-. (canceled)28. A composition comprising:{'i': 'Campylobacter jejuni', 'whole cells comprising iron-regulated polypeptides having molecular weights, as determined by 10% SDS-PAGE, of between 150 kDa and 152 kDa, between 143 kDa and 145 kDa, between 123 kDa and 125 kDa, between 88 kDa and 90 kDa, between 73 kDa and 75 kDa, between 69 kDa and 71 kDa, between 51 kDa and 53 kDa, between 50 kDa and 52 kDa, or between 38 kDa and 40 kDa; and'}a pharmaceutically acceptable carrier.29. A method comprising:{'i': Campylobacter jejuni', 'C. jejuni', 'C. jejuni, 'administering to an animal colonized by or at risk of being colonized by an amount of a composition effective to decrease colonization of the intestinal tract of the animal by , wherein the composition comprises whole cells that comprise iron-regulated polypeptides having molecular weights, as determined by 10% SDS-PAGE, of between 150 kDa and 152 kDa, between 143 kDa and 145 kDa, between 123 kDa and 125 kDa, between 88 kDa and 90 kDa, between 73 kDa and 75 kDa, between 69 kDa and 71 kDa, between 51 kDa and 53 kDa, between 50 kDa and 52 kDa, or between 38 kDa and 40 kDa.'}30. The method of wherein the animal is a mammal or a bird.31C. jejuniC. jejuni. The method of wherein the is ATCC strain PTA-6215.32Campylobacter jejuniC. jejuni. A method ...

Pump drive launch device actuator

A powertrain includes an engine, a transmission, a pump for providing pressurized hydraulic fluid and a launch clutch connected between the engine and the transmission for coupling the engine to the transmission when the launch clutch is in an engaged condition and for decoupling the engine from the transmission when the launch clutch is in a disengaged condition. A device is rotationally coupled to the engine and to the pump. The device is translatable along an axis between a first position and a second position. The device moves the launch clutch to the engaged condition when in the first position and does not move the launch clutch to the engaged condition when in the second position. A piston in communication with the pressurized hydraulic fluid provided by the pump is configured to translate the device along the axis between at least one of the first and second positions.

Hydrostatic hydraulic hybrid system

A hybrid drive system in a vehicle includes a prime mover, a starting device connected to the prime mover, and a transmission having a transmission input shaft connected to the starting device. A pump/motor is functionally interconnected between the starting device and the transmission. A first accumulator is in fluid communication with the motor/pump for storing a hydraulic fluid under pressure and a second accumulator is in fluid communication with the pump/motor for storing hydraulic fluid discharged from the first accumulator. Discharge of the first accumulator drives the pump/motor to provide a drive torque to the transmission input shaft and to provide a drive torque to the prime mover for starting the prime mover.

TORQUE TRANSFER MECHANISM AND METHOD FOR CONTROLLING IN A VEHICLE LAUNCH OPERATION

A powertrain for a vehicle is provided having an engine, a transmission, a torque transfer mechanism, a hydraulic fluid circuit, and a transmission control module. The torque transfer mechanism includes a hydraulic fluid pump and is drivingly connected to an output member of the engine and an output member of the torque transfer mechanism is drivingly connected to the input member of the transmission. The hydraulic fluid circuit has a hydraulic valve in communication with the first fluid port of the hydraulic fluid pump. The transmission control module include a control logic for operating the powertrain during a vehicle launch event. 1. A powertrain for a vehicle , the powertrain comprising:an engine having a throttle valve and an output member;a transmission having an input member and at least a first set of gears corresponding to a first gear ratio;a torque transfer mechanism including a hydraulic fluid pump, an input member, and an output member, wherein the hydraulic fluid pump includes a first fluid port and a second fluid port, the input member of the torque transfer mechanism is drivingly connected to the output member of the engine, and the output member of the torque transfer mechanism is drivingly connected to the input member of the transmission;a hydraulic fluid circuit filled with hydraulic fluid, the hydraulic fluid circuit having a hydraulic valve in communication with the first fluid port of the hydraulic fluid pump; and a first control logic for determining the rotational speed of the input member of the transmission, the rotational speed of the output member of the engine, which gear ratio the transmission is engaged, and the position of the throttle valve;', 'a second control logic for opening the hydraulic valve when the rotational speed of the input member of the transmission is zero, the rotational speed of the output member of the engine is at an idle speed, the transmission is engaged in first gear, and the throttle valve is in an open ...

Immunizing Compositions and Methods of Use

The present invention provides compositions including siderophore receptor polypeptides and porins from gram negative microbes, and preferably, lipopolysaccharide at a concentration of no greater than about 10.0 endotoxin units per milliliter. The present invention also provides methods of making and methods of using such compositions. 1. (canceled)271-. (canceled)72. A method for detecting antibody comprising:contacting antibody with a preparation to result in a mixture, wherein the preparation comprises at least two siderophore receptor polypeptides isolated from a gram negative microbe and lipopolysaccharide at a concentration of no greater than about 10.0 endotoxin units per milliliter (EU/ml);incubating the mixture under conditions to allow the antibody to specifically bind a siderophore receptor polypeptide to form an siderophore receptor polypeptide:antibody complex;detecting the siderophore receptor polypeptide:antibody complex, wherein detection of the siderophore receptor polypeptide:antibody complex indicates the presence of antibody that specifically binds a siderophore receptor polypeptide.73. The method of wherein the antibody is present in a biological sample from an animal claim 72 , and wherein the presence of antibody that specifically binds a siderophore receptor polypeptide indicates the animal may have a condition caused by a microbe expressing siderophore receptor polypeptides.74. The method of wherein the biological sample comprises blood claim 73 , milk claim 73 , or colostrum.75. The method of wherein the antibody is present in a biological sample from an animal claim 72 , wherein the animal has been immunized by administration of a composition comprising at least 2 siderophore receptor polypeptides claim 72 , and wherein the presence of antibody that specifically binds a siderophore receptor polypeptide indicates the animal has a serological response to the administration.76. The method of wherein the biological sample comprises blood claim ...

MULTI-SPEED TRANSMISSION WITH AN INTEGRATED ELECTRIC MOTOR

A transmission with an integrated electric motor includes an input member, an output member, at least four planetary gear sets, a plurality of coupling members and a plurality of torque transmitting devices. Each of the planetary gear sets includes first, second and third members. The torque transmitting devices include clutches and brakes actuatable in combinations of three to establish a plurality of forward gear ratios and at least one reverse gear ratio. 1. A powertrain in a motor vehicle comprising:an engine;an electric machine;a disconnect clutch connected between the engine and the electric machine; and an input member connected to the disconnect clutch and the electric machine;', 'an output member;', 'a plurality of planetary gear sets connected between the input member and the output member; and', 'a plurality of torque transmitting mechanisms connected between the input member, the output member, and the plurality of planetary gear sets, wherein one of the plurality of torque transmitting mechanisms is a launch clutch connected to one of the plurality of planetary gear sets, wherein the launch clutch is engaged during a first gear and a reverse gear and is slipped during launch of the motor vehicle from a stop., 'a transmission including2. The powertrain of wherein the plurality of planetary gear sets includes four planetary gear sets and the plurality of torque transmitting mechanisms include seven torque transmitting mechanisms.3. The powertrain of wherein engagement of the launch clutch claim 2 , the disconnect clutch claim 2 , a second of the seven torque transmitting devices claim 2 , and a fifth of the seven torque transmitting devices provides the first gear.4. The powertrain of wherein engagement of the launch clutch claim 3 , the disconnect clutch claim 3 , a fifth of the seven torque transmitting devices claim 3 , and a sixth of the seven torque transmitting devices provides the reverse gear.5. The powertrain of wherein the input member of the ...

HYBRID POWERTRAIN

A powertrain includes an engine, electric motor, disconnect clutch and a transmission. The transmission has an input member, an output member, at least four planetary gear sets, a plurality of coupling members and a plurality of torque transmitting devices. Each of the planetary gear sets includes first, second and third members. The torque transmitting devices include clutches and brakes actuatable in combinations of three to establish a plurality of forward gear ratios and at least one reverse gear ratio. The electric motor is connected to the input of the transmission and the engine is selectively connected to the input member through the disconnect clutch. A controller is configured to control the operation of the powertrain. 1. A powertrain of a vehicle , the powertrain comprising:an engine for generating an engine driving torque; first, second, third and fourth planetary gear sets each having first, second and third members;', 'three interconnecting members continuously interconnecting a member of the first, second, third and fourth planetary gear sets with another member of the first, second, third and fourth planetary gear sets; and', 'six torque transmitting mechanisms wherein three of the six torque transmitting mechanisms are each selectively engageable to interconnect at least one of the first, second and third members with at least one other of the first, second, third members and wherein three of the six torque transmitting mechanisms are each selectively engageable to interconnect at least one of the first, second and third members with a stationary member, and wherein the six torque transmitting mechanisms are selectively engageable in combinations of at least three to establish a plurality of forward speed ratios and at least one reverse speed ratio between the input member and the output member; and, 'a transmission having an input member and an output member, wherein the transmission further includesa disconnect clutch connected to the engine and ...

BINARY AND FRICTION CLUTCH ASSEMBLY

A transmission is provided having an input member, an output member, four planetary gear sets, a plurality of coupling members and a plurality of torque transmitting devices. Each of the planetary gear sets includes first, second and third members. The torque transmitting devices include clutches and brakes actuatable in combinations of two to establish a plurality of forward gear ratios and one reverse gear ratio. One of the torque transmitting devices includes a friction clutch and a binary clutch which have a spring-ball structure disposed therebetween. 1. A torque transmitting device assembly for selectively transmitting torque between a first member and a second member , the torque transmitting device comprising:a friction clutch having a backing plate structure against which the friction clutch acts;a biasing member disposed in the backing plate structure with a ball disposed adjacent to the biasing member; anda binary clutch disposed adjacent to the backing plate structure.2. The torque transmitting device assembly of claim 1 , further comprising an actuator configured to engage both the friction clutch and the binary clutch.3. The torque transmitting device assembly of claim 2 , wherein the actuator is configured to apply a first pressure to the friction clutch to engage the friction clutch while the binary clutch remains disengaged in a first engaged position claim 2 , and the actuator being configured to apply a second pressure to the friction clutch to engage the binary clutch in a second engaged position claim 2 , the second pressure being greater than the first pressure.4. The torque transmitting device assembly of claim 3 , wherein the biasing member is a first biasing member claim 3 , the torque transmitting device assembly further comprising a second biasing member and a stop claim 3 , the second biasing member disposed between the stop and the backing plate structure claim 3 , the second biasing member being configured to bias the backing plate ...

MULTI-SPEED TRANSMISSION

A transmission is provided having an input member, an output member, four planetary gear sets, a plurality of coupling members and a plurality of torque transmitting devices. Each of the planetary gear sets includes first, second and third members. The torque transmitting devices include clutches and brakes actuatable in combinations of two to establish a plurality of forward gear ratios and one reverse gear ratio. One of the torque transmitting devices includes a friction clutch disposed in parallel with a binary clutch. 1. A torque transmitting device assembly for selectively transmitting torque between a first member and a second member , the torque transmitting device comprising:a binary clutch;a friction clutch disposed in parallel with the binary clutch; andan actuator configured to engage both the friction clutch and the binary clutch.2. The torque transmitting device assembly of claim 1 , further comprising a friction clutch backing plate that is acted against by the friction clutch claim 1 , the friction clutch backing plate configured to selectively apply pressure on the binary clutch.3. The torque transmitting device assembly of claim 2 , further comprising a biasing member and a binary clutch backing plate claim 2 , the biasing member being configured to bias the friction clutch backing plate away from the binary clutch.4. The torque transmitting device assembly of claim 3 , wherein the biasing member is disposed between the friction clutch backing plate and the binary clutch backing plate claim 3 , the friction clutch backing plate being configured to compress the biasing member such that when the biasing member is compressed to an engaged position claim 3 , the friction clutch backing plate engages the binary clutch.5. The torque transmitting device assembly of claim 4 , wherein the binary clutch is disposed adjacent to the friction clutch claim 4 , the friction clutch being disposed between the binary clutch and the actuator.6. The torque transmitting ...

Polypeptides and Immunizing Compositions Containing Gram Positive Polypeptides and Methods of Use

The present invention provides isolated polypeptides isolatable from a Staphylococcus spp. Also provided by the present invention are compositions that include one or more of the polypeptides, and methods for making and methods for using the polypeptides.

Polypeptides and Immunizing Compositions Containing Gram Positive Polypeptides and Methods of Use

The present invention provides isolated polypeptides isolatable from a Staphylococcus spp. Also provided by the present invention are compositions that include one or more of the polypeptides, and methods for making and methods for using the polypeptides.

Polypeptides and Immunizing Compositions Containing Gram Positive Polypeptides and Methods of Use

The present invention provides isolated polypeptides isolatable from a spp. Also provided by the present invention are compositions that include one or more of the polypeptides, and methods for making and methods for using the polypeptides. 150-. (canceled)51Staphylococcus aureus. An enriched polypeptide having immunogenic activity and a mass fingerprint when digested with trypsin that includes all polypeptide fragments present in a mass fingerprint of a reference polypeptide when digested with trypsin , wherein the reference polypeptide has a molecular weight of 35 kDa as determined by electrophoresis on a sodium dodecyl sulfate-polyacrylamide gel and is expressed by ATCC strain 19636 when incubated in media comprising 2 ,2′-dipyridyl at a concentration of 1600 μM and not expressed at a detectable level when grown in the media without the 2 ,2′-dipyridyl. This application claims the benefit of U.S. Provisional Application Ser. No. 60/652,843, filed Feb. 14, 2005, which is incorporated by reference herein.Gram-positive bacteria are a remarkably diverse group of organisms that cause a variety of diseases in both humans and animals. Some of the pathogens recognized as important in human and/or animal health include bacteria belonging to the families of Corynebacteriaceae, Enterococcacae, Micrococcaceae, Mycobacteriaceae, Nocardiaceae, and Peptococcaceae, which include such bacterial species as spp., spp., spp., spp., spp., spp., spp., spp., spp., spp., spp., spp., spp., and spp. These pathogens cause a multitude of clinical manifestations in many different animal species. The treatment for such infections has historically been antibiotics that attack the common structures and functions of gram-positive organisms. However, many of the more ubiquitous gram-positive organisms have developed resistance to several classes of antibiotics, making treatment of infections difficult. The widespread use of antibiotics in the treatment of bacterial diseases in both humans and ...

TOROIDAL TRACTION DRIVE TRANSMISSION

A continuously variable transmission includes a gearbox with a forward mode and a reverse mode. The gearbox includes a plurality of gear members and further includes at least two torque transmitting devices such as, a clutch and a brake that are selectively employed to engage various combinations of the gear members such that a particular combination is associated with one of the forward mode and the reverse mode. 1. A transmission for a motor vehicle , the transmission comprising:an input member;an output member;a variator having an input coupled to the input member and an output;a first transfer gear set having a first gear coupled to the output of the variator and a second gear;a planetary gear set having a first member, a second member and a third member, wherein one of the members of the planetary gear set is coupled to the second gear of the first transfer gear set;a friction brake configured to selectively couple one of the members of the planetary gear set to a stationary member;a second transfer gear set having a first gear coupled to one of the members of the planetary gear set and a second gear in mesh with the first gear; anda friction clutch selectively engageable to interconnect the first gear of the first transfer gear set with one of the members of the planetary gear set, andwherein a plurality of forward speeds are established between the input member and the output member through manipulation of the variator.2. The transmission for a motor vehicle of wherein the third member of the planetary gear set is coupled to the second gear of the first transfer gear set.3. The transmission for a motor vehicle of wherein the first member is a sun gear claim 1 , the second member is a planet gear carrier member and the third member is a ring gear.4. The transmission for a motor vehicle of wherein the friction brake selectively couples the planet gear carrier member of the planetary gear set to the stationary member.5. The transmission for a motor vehicle of ...

MULTI-SPEED TRANSMISSION AND BACKING PLATE

A transmission is provided having an input member, an output member, at least three planetary gear sets, a plurality of coupling members, and a plurality of torque transmitting devices. Each of the planetary gear sets includes first, second and third members. The torque transmitting devices include clutches and brakes actuatable in combinations of two to establish at least ten forward gear ratios and one reverse gear ratio. At least one of the torque transmitting mechanisms includes a backing plate having an annular outlet for distributing cooling fluid. 1. A clutch assembly for use in an automatic transmission , the clutch assembly comprising:a plurality of interleaved clutch plates selectively engageable to interconnect a first member with a second member, wherein at least one first clutch plate of the plurality of interleaved clutch plates is attached to the first member and at least one second clutch plate of the plurality of interleaved clutch plates is attached to the second member; anda backing plate disposed adjacent to the plurality of interleaved clutch plates, the plurality of interleaved clutch plates being configured to be compressed against the backing plate when the clutch assembly is engaged, the backing plate comprising a first piece and a second piece, the first and second pieces cooperating to form an annular passageway therebetween.2. The clutch assembly of claim 1 , wherein the first piece of the backing plate has an outer side claim 1 , the first piece forming a plurality of inlet openings to the annular passageway through the outer side of the first piece.3. The clutch assembly of claim 2 , wherein the plurality of inlet openings are formed in the outer side of the first piece along a circumference of the first piece.4. The clutch assembly of claim 3 , wherein the first and second pieces each have an annular shape.5. The clutch assembly of claim 4 , wherein the first and second pieces cooperate to form an annular outlet of the annular ...

ELECTROMECHANICAL CLUTCH AND TRANSMISSION

A transmission is provided having an input member, an output member, at least four planetary gear sets, a plurality of coupling members and a plurality of torque transmitting mechanisms. Each of the planetary gear sets includes first, second and third members. The torque transmitting mechanisms include clutches and brakes actuatable in combinations of two to establish a plurality of forward gear ratios and one reverse gear ratio. An electromechanical rotating clutch assembly is provided that includes a rotor, an armature, and an electromagnetic coil. The electromagnetic coil is operable to selectively engage the rotor with the armature. 1. An electromechanical rotating clutch assembly for use in an automatic transmission having a first transmission part configured to rotate during at least one output gear speed of the automatic transmission and a second transmission member configured to rotate during at least one output gear speed of the automatic transmission , the electromechanical rotating clutch assembly being selectively engageable to interconnect the first transmission member with the second transmission member , the electromechanical rotating clutch assembly comprising:a rotor coupled to the first transmission member;an armature coupled to the second transmission member; andan electromagnetic coil, the electromagnetic coil being operable to selectively engage the rotor with the armature.2. The electromechanical rotating clutch assembly of claim 1 , wherein the rotor has a rotor surface claim 1 , wherein the armature has an armature surface claim 1 , and wherein the electromagnetic coil is operable to selectively interconnect the armature surface with the rotor surface claim 1 , the armature surface and the rotor surface being in contact with each other when interconnected.3. The electromechanical rotating clutch assembly of claim 2 , wherein the rotor surface is the sole portion of the rotor in contact with the armature when the electromechanical rotating ...

AUTOMATIC TRANSMISSION GEAR AND CLUTCH ARRANGEMENT

A transmission is provided having an input member, an output member, four planetary gear sets, a four coupling members and a six torque-transmitting mechanisms. Further, a hydraulic fluid control circuit is provided for controlling the operation of the plurality of torque-transmitting devices. The hydraulic fluid control circuit receives pressurized hydraulic fluid from an off-axis hydraulic fluid pump and has a plurality of fluid passages disposed in the transmission house, input member and other coupling members. 1. A multi-speed transmission comprising:a transmission housing;a first, a second, a third, and a fourth planetary gear sets each having a first, a second, and a third members;an input member rotatably supported by the transmission housing, the input member continuously interconnected with the second member of the second planetary gear set;an output member rotatably supported by the transmission housing, the output member continuously interconnected to the second member of the fourth planetary gear set;four interconnecting members each continuously interconnecting one of the first, second, and third members of the planetary gear sets with another of the first, second, and third members of the planetary gear sets;an intermediate member rotatably supported by the one of the four interconnecting members;six torque transmitting mechanisms each selectively interconnecting at least one of the first, second, and third members of the planetary gear sets with at least another of the first members, second members, third members of the planetary gear sets, the intermediate member, or the transmission housing; andwherein the torque transmitting mechanisms are selectively engageable in combinations of at least three to establish ten forward speed ratios and at least one reverse speed ratio between the input member and the output member.2. The multi-speed transmission of wherein a first of the four interconnecting members continuously interconnects the first member of ...

Polypeptides and Immunizing Compositions Containing Gram Positive Polypeptides and Methods of Use

The present invention provides isolated polypeptides isolatable from a spp. Also provided by the present invention are compositions that include one or more of the polypeptides, and methods for making and methods for using the polypeptides. 150-. (canceled)51Staphylococcus aureus. An enriched polypeptide having immunogenic activity and a mass fingerprint when digested with trypsin that includes all polypeptide fragments present in a mass fingerprint of a reference polypeptide when digested with trypsin , wherein the reference polypeptide has a molecular weight of 55 kDa as determined by electrophoresis on a sodium dodecyl sulfate-polyacrylamide gel and is expressed by ATCC strain 19636 when incubated in media comprising 2 ,2′-dipyridyl at a concentration of 1600 μM and not expressed at a detectable level when grown in the media without the 2 ,2′-dipyridyl. This application claims the benefit of U.S. Provisional Application Ser. No. 60/652,843, filed Feb. 14, 2005, which is incorporated by reference herein.Gram-positive bacteria are a remarkably diverse group of organisms that cause a variety of diseases in both humans and animals.Some of the pathogens recognized as important in human and/or animal health include bacteria belonging to the families of Corynebacteriaceae, Enterococcacae, Micrococcaceae, Mycobacteriaceae, Nocardiaceae, and Peptococcaceae, which include such bacterial species as spp., spp., spp., spp., spp., spp., spp., spp., spp., spp., spp., spp., spp., and spp. These pathogens cause a multitude of clinical manifestations in many different animal species. The treatment for such infections has historically been antibiotics that attack the common structures and functions of gram-positive organisms. However, many of the more ubiquitous gram-positive organisms have developed resistance to several classes of antibiotics, making treatment of infections difficult. The widespread use of antibiotics in the treatment of bacterial diseases in both humans and food ...

FLUID SUPPLY FOR ROTATING PISTON

A transmission is provided having an input member, an output member, at least four planetary gear sets, coupling members, and torque transmitting devices. Each of the planetary gear sets includes first, second and third members. The torque transmitting devices include clutches and brakes actuatable in combinations of two to establish at least eleven forward gear ratios and one reverse gear ratio. A clutch assembly for use in an automatic transmission is provided that includes an apply piston and a stationary fluid supply member. The apply piston is configured to rotate during at least one gear speed of the automatic transmission. The stationary fluid supply member has portions forming a channel in the stationary fluid supply member and defining an outlet end of the channel. The stationary fluid supply member is configured to supply fluid to the apply piston through the outlet end of the channel. 1. A clutch assembly for use in an automatic transmission , the clutch assembly comprising:an apply piston configured to rotate during at least one output gear speed of the automatic transmission;a stationary fluid supply member having portions forming a channel in the stationary fluid supply member and defining an outlet end of the channel, the stationary fluid supply member being configured to supply fluid to the apply piston through the outlet end of the channel; andat least one member seal contacting the stationary fluid supply member, the member seal being disposed between the stationary fluid supply member the apply piston.2. The clutch assembly of claim 1 , wherein the portions forming the outlet end of the channel of the stationary fluid supply member are at least partially disposed radially outwardly from an outer side of the apply piston.3. The clutch assembly of claim 2 , further comprising a central input member to the transmission claim 2 , the apply piston being disposed a first distance from the central input member claim 2 , and the portions forming the ...

FLUID COUPLING

A fluid coupling is provided having a housing, an input member, a pump assembly, and a turbine assembly. The pump assembly includes a pump portion disposed opposite a turbine portion of the turbine assembly. The turbine assembly further includes a damper assembly having a plurality of springs disposed radially between the turbine portion and a transmission input shaft. 1. A fluid coupling for transferring torque from an engine to a transmission , the fluid coupling comprising:a housing;an input member fixedly connected for common rotation with a flywheel of the engine;a pump assembly connected for common rotation with the input member, the pump assembly including a pump member and a plurality of pump blades, and wherein the pump member is rotatably supported by the housing and includes a pump portion in which is disposed the plurality of pump blades, anda turbine assembly including a turbine member, a plurality of turbine blades, a damper assembly, and an annular hub member, and wherein the hub member is fixed for common rotation with the input shaft of the transmission, the turbine member is rotatably supported by the hub member, and the turbine member includes a turbine portion in which is disposed the plurality of turbine blades; andwherein the pump portion and the turbine portion are disposed at the outer periphery of the pump assembly and turbine assembly, respectively, and the plurality of springs are disposed radially between the turbine portion and the hub member.2. The fluid coupling of wherein the input member has a plate portion and an edge portion claim 1 , and the pump member has a plate portion and an edge portion claim 1 , and wherein the edge portion of the input member is disposed on the outer periphery of the plate portion claim 1 , the edge portion of the pump member is disposed on the outer periphery of the plate portion claim 1 , the edge portion of the input member is extended axially rearward from the plate portion claim 1 , the edge portion ...

Compositions produced using enteric pathogens and methods of use

The present invention provides compositions including polypeptides having the characteristics of polypeptides expressed by a reference microbe such E. coli or Salmonella . Examples of Salmonella strains that can be used include, for instance, S. enterica serovar Newport, S. enterica serovar Enteritidis, S. enterica serovar Typhimurium , and S. enterica serovar Dublin. Also provided are compositions including polypeptides having a particular molecular weight and a mass fingerprint that includes polypeptide fragments having a particular set of masses, or polypeptides having an amino acid sequence with at least about 95% identity with an amino acid sequence, wherein the polypeptide has seroreactive activity. The present invention also provides methods of making and methods of using such compositions.

Continuously variable transmission with chain output

A multi-mode continuously variable transmission in a powertrain of a motor vehicle includes a continuously variable unit connected to a planetary gear set arrangement. The planetary gear set arrangement generally includes two planetary gear sets, two brakes, and one clutch and provides multiple modes of ratio selection between the continuously variable unit and a transmission output member. The transmission output member is connected to a chain driven final having only three axes of rotation.

Retrofit LED Lighting System

A retrofit LED lighting system for replacement of existing metal halide lamp driven by magnetic ballast is provided. The retrofit lamp includes a circuit that converts the AC current supplied by magnetic ballast to DC current required for illuminating the LEDs.

POLYPEPTIDES AND IMMUNIZING COMPOSITIONS CONTAINING GRAM POSITIVE POLYPEPTIDES AND METHODS OF USE

The present invention provides isolated polypeptides isolatable from a spp. Also provided by the present invention are compositions that include one or more of the polypeptides, and methods for making and methods for using the polypeptides. 129-. (canceled)30. A composition comprising:a combination of isolated antibodies that specifically binds at least five polypeptides, each polypeptide having a molecular weight of 88 kDa, 55 kDa, 38 kDa, 37 kDa, 36 kDa, 35 kDa, or 33 kDa as determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis;{'i': 'Staphylococcus aureus', 'wherein the polypeptide having a molecular weight of 88 kDa comprises the amino acid sequences depicted in SEQ ID NO:1, SEQ ID NO:2, SEQ ID NO:3, SEQ ID NO:4, SEQ ID NO:5, SEQ ID NO:6, SEQ ID NO:7, SEQ ID NO:9, SEQ ID NO:10, SEQ ID NO:11, SEQ ID NO:12, SEQ ID NO:13, SEQ ID NO:14, SEQ ID NO:15, SEQ ID NO:16, SEQ ID NO:17, SEQ ID NO:19, SEQ ID NO:20, SEQ ID NO:21, SEQ ID NO:22, SEQ ID NO:24, SEQ ID NO:25, SEQ ID NO:26, SEQ ID NO:27, SEQ ID NO:28, SEQ ID NO:29, SEQ ID NO:30, SEQ ID NO:31, SEQ ID NO:32, and SEQ ID NO:33, and is expressed by ATCC strain 19636 at a greater level when grown in medium comprising 2,2-dipyridyl at a concentration of 1600 μM compared to when grown in the medium without the 2,2-dipyridyl;'}{'i': 'Staphylococcus aureus', 'wherein the polypeptide having a molecular weight of 55 kDa comprises the amino acid sequences depicted in SEQ ID NO:35, SEQ ID NO:37, SEQ ID NO:39, SEQ ID NO:40, SEQ ID NO:41, SEQ ID NO:42, SEQ ID NO:43, SEQ ID NO:44, SEQ ID NO:45, SEQ ID NO:46, SEQ ID NO:49, SEQ ID NO:51, SEQ ID NO:52, SEQ ID NO:53, SEQ ID NO:54, SEQ ID NO:57, SEQ ID NO:58, and SEQ ID NO:59, and is expressed by ATCC strain 19636 at a greater level when grown in medium comprising 2,2-dipyridyl at a concentration of 1600 μM compared to when grown in the medium without the 2,2-dipyridyl;'}{'i': 'Staphylococcus aureus', 'wherein the polypeptide having a molecular weight of 38 kDa ...

POLYPEPTIDES OF FUSOBACTERIUM AND METHODS OF USE

The present invention provides isolated polypeptides isolatable from a spp. Also provided by the present invention are compositions that include one or more of the polypeptides, and methods for making and methods for using the polypeptides. 130-. (canceled)31. A composition comprising an isolated polypeptide having at least 85% similarity to amino acids 63-423 of SEQ ID NO:2; anda pharmaceutically acceptable adjuvant.32. The composition of further comprising:{'i': 'Fusobacterium necrophorum', 'isolated polypeptides having molecular weights of 92 kDa to 79 kDa, 73 kDa to 63 kDa, 62 kDa to 58 kDa, and 57 kDa to 47 kDa, wherein the polypeptides are isolatable from a when incubated in media comprising an iron chelator and not isolatable when grown in the media without the iron chelator,'}{'i': Fusobacterium necrophorum', 'Fusobacterium necrophorum, 'isolated polypeptides having molecular weights of 108 kDa to 98 kDa and 79 kDa to 69 kDa, wherein the polypeptides are isolatable from a when incubated in media comprising an iron chelator, are expressed by the when incubated in media without the iron chelator and expressed at an enhanced level during growth in media comprising an iron chelator; and'}a pharmaceutically acceptable adjuvant.33. The composition of further comprising a protein having at least 85% similarity to amino acids 63-714 of SEQ ID NO:4.34. The composition of further comprising a protein having at least 85% similarity to amino acids 63-736 of SEQ ID NO:6.35. The composition of further comprising a protein having at least 85% similarity to amino acids 63-714 of SEQ ID NO:4. and a protein having at least 85% similarity to amino acids 63-736 of SEQ ID NO:6.36. A method comprising:{'claim-ref': {'@idref': 'CLM-00031', 'claim 31'}, 'administering to a subject an amount of the composition of effective to induce the subject to produce antibody that specifically binds to at least one polypeptide of the composition.'}37. A method for treating an infection in a ...

HYDRAULICALLY ACTUATED TRANSFER CASE

A drive torque transfer case is provided. The transfer case includes an input shaft, an output shaft, a gear assembly coupled to the input shaft, and a range clutch assembly coupled to the output shaft. The range clutch assembly includes a clutch member and a multi-piston actuator configured to receive a pressurized transmission fluid for selectively axially translating the clutch member to engage a component of the gear assembly for transmitting a drive torque from the input shaft to the output shaft. The multi-piston actuator includes an internal piston having a first annular surface area A and a third annular surface area A and an external piston having a second annular surface area A and a fourth annular surface area A The A and A are in hydraulic communication with a first hydraulic chamber, and A and A are in hydraulic communication with a second hydraulic chamber. 1. A drive torque transfer case for a vehicle having a transmission , comprising:an input shaft extending along a longitudinal axis A;an output shaft co-axially aligned with the input shaft;a gear assembly coupled to the input shaft; anda range clutch assembly coupled to the output shaft,wherein the range clutch assembly includes a clutch member and a multi-piston actuator configured to receive a pressurized transmission fluid from the transmission for selectively axially translating the clutch member to engage a component of the gear assembly for transmitting a drive torque from the input shaft to the output shaft.2. The drive torque transfer case of claim 1 , further comprising a transfer case housing;wherein the gear assembly includes a sun gear rotationally fixed to the input shaft, a ring gear non-rotationally fixed to the transfer case housing, and planetary gear carrier having a plurality of planetary gears meshed between the sun gear and the ring gear;wherein the clutch member is a dog clutch splined to the output shaft and axially translatable in a first axial direction and in an opposite ...

COMPOSITIONS PRODUCED USING ENTERIC PATHOGENS AND METHODS OF USE

The present invention provides compositions including polypeptides having the characteristics of polypeptides expressed by a reference microbe such or . Examples of strains that can be used include, for instance, serovar Newport, serovar Enteritidis, serovar Typhimurium, and serovar Dublin. Also provided are compositions including polypeptides having a particular molecular weight and a mass fingerprint that includes polypeptide fragments having a particular set of masses, or polypeptides having an amino acid sequence with at least about 95% identity with an amino acid sequence, wherein the polypeptide has seroreactive activity. The present invention also provides methods of making and methods of using such compositions. 138-. (canceled)39. A composition comprising:{'i': 'Salmonella enterica', 'a first isolated iron-regulated polypeptide from serovar Newport having a molecular weight of about 82 kDa as measured following electrophoresis on an SDS-polyacrylamide gel, wherein the first isolated iron-regulated polypeptide, if digested with trypsin, produces polypeptide fragments having masses of 628.39 Da±300 parts per million (ppm), 643.37 Da±300 ppm, 771.42 Da±300 ppm, 830.45 Da±300 ppm, 872.46 Da±300 ppm, 990.55 Da±300 ppm, 1082.61 Da±300 ppm, 1207.58 Da±300 ppm, 1324.75 Da±300 ppm, 1377.66 Da±300 ppm, 1463.74 Da±300 ppm, 1499.71 Da±300 ppm, 1633.84 Da±300 ppm, 1618.77 Da±300 ppm, 1727.83 Da±300 ppm, 1871.88 Da±300 ppm, 1980.96 Da±300 ppm, 1997.06 Da±300 ppm, 2192.94 Da±300 ppm, and 2331.05 Da±300 ppm;'}{'i': 'Salmonella enterica', 'a second isolated iron-regulated polypeptide from serovar Newport having a molecular weight of about 80 kDa as measured following electrophoresis on an SDS-polyacrylamide gel, wherein the second isolated iron-regulated polypeptide, if digested with trypsin, produces polypeptide fragments having masses of 848.45 Da±300 ppm, 918.45 Da±300 ppm, 1040.60 Da±300 ppm, 1097.62 Da±300 ppm, 1309.63 Da±300 ppm, 1335.71 Da±300 ppm, 1341.66 Da±300 ppm ...

CONTINUOUSLY VARIABLE TRANSMISSION WITH CHAIN OUTPUT

A multi-mode continuously variable transmission in a powertrain of a motor vehicle includes a continuously variable unit connected to a planetary gear set arrangement. The planetary gear set arrangement generally includes two planetary gear sets, two brakes, and one clutch and provides multiple modes of ratio selection between the continuously variable unit and a transmission output member. The transmission output member is connected to a chain driven final having only three axes of rotation. 1. A powertrain for a motor vehicle comprising:a transmission input member;a transmission output member;an intermediate member;a continuously variable unit having a first pulley pair connected for common rotation with the transmission input member, a second pulley pair connected for common rotation with the intermediate member, and an endless member wrapped around the first pulley pair and the second pulley pair;a first planetary gear set connected to the intermediate member;a second planetary gear set connected to the first planetary gear member and to the transmission output member;a plurality of torque transmitting mechanisms interconnected to the planetary gear arrangement;a chain drive connected for common rotation with the transmission output member;a transfer member connected for common rotation with the chain drive; anda final drive planetary gear set connected for common rotation with the transfer member,wherein selective engagement of the plurality of torque transmitting mechanisms and selective movement of the first pulley and second pulley provides two forward ranges of continuous gear ratios between the transmission input member and the transmission output member.2. The powertrain of wherein the first planetary gear set and the second planetary gear sets each include a first member claim 1 , a second member claim 1 , and a third member.3. The powertrain of further comprising a first interconnecting member rotationally fixed to the first member of the first ...

Retrofit LED Lighting System

A retrofit LED lighting system for replacement of existing metal halide lamp driven by magnetic ballast is provided. The retrofit lamp includes a circuit that converts the AC current supplied by magnetic ballast to DC current required for illuminating the LEDs. 1. A retrofit LED lamp for replacing a socket type metal halide lamp driven by a magnetic ballast , the said lamp comprising:a string of LED mounted on an MCPCB plate;a housing that serves as a mean for dissipating the heat generated by LED; a diffuser placed over the MCPCB plate to diffuse the light emitted by LED;a PCB circuit to provide the voltage input to the string of LED, the said PCB circuit comprises a bridge rectifier to convert the output from the magnetic ballast to DC current required to illuminate the string of LED; anda base connector adapted to fit into the socket meant for metal halide lamp, the said base connector provides electrical connection between the output of magnetic ballast and the said PCB circuit;wherein the retrofit LED lamp works on the electric current supplied by magnetic ballast and can operate without removing the magnetic ballast.2. The retrofit LED lamp of wherein the MCPCB plate is fabricated from material consisting of aluminum alloy or dielectric polymer.3. The retrofit LED lamp of wherein the string of LED is mounted on the surface of the MCPCB plate.4. The retrofit LED lamp of wherein the diffuser is made from composite material of polymer and glass fiber claim 1 , or from a polycarbonate/acrylic material.5. The retrofit LED lamp of wherein the diffuser diffuses the light emitted by the string of LEDs.6. The retrofit LED lamp of wherein the housing is fabricated from the material consisting of aluminum claim 1 , copper claim 1 , thermoplastic material claim 1 , or natural graphite.7. The retrofit LED lamp of wherein the bridge rectifier that converts AC waveform into DC waveform consists of four diodes arranged in a bridge manner.8. The retrofit LED lamp of wherein ...

YERSINIA SPP. POLYPEPTIDES AND METHODS OF USE

The present invention provides isolated polypeptides isolatable from a spp. Also provided by the present invention are compositions that include one or more of the polypeptides, and methods for making and methods for using the polypeptides. 162-. (canceled)63. A method for treating an infection in a subject comprising:{'i': 'Yersinia', 'administering an effective amount of a composition to a subject having or at risk of having an infection caused by a spp., wherein the composition comprisesisolated polypeptides having molecular weights of 83 kDa, 70 kDa, and 66 kDa, wherein molecular weight is determined by electrophoresis on a sodium dodecyl sulfate-polyacrylamide gel, wherein the polypeptides are expressed by a Yersinia enterocolitica at a greater level when incubated in media comprising an iron chelator than when grown in the media without the iron chelator; the amino acid sequences of SEQ ID NO:34, SEQ ID NO:35, SEQ ID NO:36, SEQ ID NO:37, SEQ ID NO:38, SEQ ID NO:39, SEQ ID NO:40, SEQ ID NO:41, SEQ ID NO:42, SEQ ID NO:43, SEQ ID NO:44, SEQ ID NO:45, SEQ ID NO:46, SEQ ID NO:47, SEQ ID NO:48, SEQ ID NO:49, SEQ ID NO:50, SEQ ID NO:51, SEQ ID NO:52, SEQ ID NO:53, SEQ ID NO:54, SEQ ID NO:55, SEQ ID NO:56, SEQ ID NO:57, and SEQ ID NO:58, or', 'the amino acid sequences of SEQ ID NO:59, SEQ ID NO:60, SEQ ID NO:61, SEQ ID NO:62, SEQ ID NO:63, SEQ ID NO:64, SEQ ID NO:65, SEQ ID NO:66, SEQ ID NO:68, SEQ ID NO:69, SEQ ID NO:70, SEQ ID NO:71, SEQ ID NO:72, SEQ ID NO:73, SEQ ID NO:74, SEQ ID NO:75, SEQ ID NO:76, SEQ ID NO:77, SEQ ID NO:79, SEQ ID NO:80, SEQ ID NO:81, SEQ ID NO:82, and one selected from the group consisting of: SEQ ID NO:67 and SEQ ID NO:78;, 'wherein the isolated polypeptide with a molecular weight of 83 kDa compriseswherein the isolated polypeptide with a molecular weight of 70 kDa comprises the amino acid sequences of SEQ ID NO:112, SEQ ID NO:113, SEQ ID NO:114, SEQ ID NO:115, SEQ ID NO:116, SEQ ID NO:117, SEQ ID NO:118, SEQ ID NO:119, SEQ ID NO:120, SEQ ID ...

MELDRUM'S ACID, BARBITURIC ACID AND PYRAZOLONE DERIVATIVES SUBSTITUTED WITH HYDROXYLAMINE AS HNO DONORS

The disclosed subject matter provides certain N-substituted hydroxylamine derivative compounds, pharmaceutical compositions and kits comprising such compounds, and methods of using such compounds or pharmaceutical compositions. In particular, the disclosed subject matter provides methods of using such compounds or pharmaceutical compositions for treating, preventing, or delaying the onset and/or development of a disease or condition. In some embodiments, the disease or condition is selected from cardiovascular diseases, ischemia, reperfusion injury, cancerous disease, pulmonary hypertension and conditions responsive to nitroxyl therapy. 23.-. (canceled)4. The compound of claim 1 , wherein R is C-Calkyl claim 1 , wherein the alkyl is unsubstituted or substituted with one or more substituents.5. The compound of claim 1 , wherein R is C-Calkyl.6. The compound of claim 1 , wherein R is —C(═NOR)R.7. The compound of claim 1 , wherein R is —C(═NOR)R; and Rand Rare independently C-Calkyl.8. The compound of any one of claim 1 , and to claim 1 , wherein X and Z are each —O—.910.-. (canceled)11. The compound of any one of claim 1 , and to claim 1 , wherein Y is —CRR—.12. The compound of any one of claim 1 , and to wherein Y is —C(═O)—.1319.-. (canceled)21. A pharmaceutical composition comprising:{'claim-ref': {'@idref': 'CLM-00001', 'claim 1'}, 'a compound of ; and'}a pharmaceutically acceptable excipient.22. A method of treating a disease or condition selected from cardiovascular diseases claim 1 , ischemia claim 1 , reperfusion injury claim 1 , cancerous disease claim 1 , pulmonary hypertension and conditions responsive to nitroxyl therapy claim 1 , comprising administering a compound of to a subject in need thereof.23. A method of modulating in vivo nitroxyl levels claim 1 , comprising administering a compound of to a subject in need thereof.24. A kit comprising:{'claim-ref': {'@idref': 'CLM-00001', 'claim 1'}, 'a compound of ; and'}instructions for treating a condition ...

Apparatus for Correcting Bullet Cartridge Casing Neck Distortions

An apparatus for correcting an aberration in a bullet casing's neck, the apparatus incorporating a support frame; a collet chuck and collet sleeve combination whose collet chuck presents a circumferential array of jaws having longitudinal ends, wherein the collet chuck further has a throat extending longitudinally from the jaws' longitudinal ends; a bullet ogive centering annular land fixedly attached to or formed wholly with the collet chuck, the bullet ogive centering annular land being positioned at an oppositely longitudinal end of the throat; rotatable mounting conical bearings and bushings which attach the collet chuck and collet sleeve combination to the support frame; and a turn wheel connected operatively to the collet chuck and collet sleeve combination. 1. An apparatus for correcting a distortion in a bullet cartridge casing's neck , said casing further having a body and a rim , said apparatus comprising:(a) a frame;(b) a collet chuck and collet sleeve combination, said combination's collet chuck having a circumferential array of jaws having longitudinal ends, said combination's collet chuck further having a throat bounded by the circumferential array of jaws;(c) means for, upon a receipt of a bullet within the bullet cartridge casing's neck, aligning said bullet, said means begin positioned within the throat;(d) mounting means attaching the collet chuck and collet sleeve combination to the frame, said means being adapted for facilitating rotation of said combination; and(e) turning means connected operatively to the collet chuck and collet sleeve combination.2. The apparatus of wherein the means for aligning said bullet comprises a plurality of flexible jaw ties or a bullet ogive centering land.3. The apparatus of wherein the oppositely longitudinal end of the collet chuck is externally conically flared.4. The apparatus of wherein an oppositely longitudinal end of the collet sleeve is internally conically flared claim 3 , said end being fitted for ...

SEALED LOW LEAK CONTROLS SYSTEM IN AN AUTOMATIC TRANSMISSION

A transmission sealed low leak controls system includes a controls system having a first fluid for operation of the controls system provided by a first pump at a first pressure. A transmission input shaft is provided. A planetary gear set is connected to the transmission input shaft by a clutch assembly. A second pump provides a second fluid different from the first fluid for cooling and lubrication of the at least one clutch assembly at a second pressure lower than the first pressure. A torque converter is connected to the transmission input shaft. The second pump further provides the second fluid to the torque converter. 1. A transmission sealed low leak controls system , comprising:a controls system having a fluid for operation of the controls system provided by a first pump;a transmission input shaft;at least one planetary gear set;at least one clutch assembly connecting the at least one planetary gear set to the transmission input shaft; anda second pump providing a fluid for cooling and lubrication of the at least one clutch assembly.2. The transmission sealed low leak controls system of claim 1 , wherein the fluid for operation of the controls system is different from the fluid for cooling and lubrication of the at least one clutch assembly.3. The transmission sealed low leak controls system of claim 1 , wherein the fluid for operation of the controls system is a synthetic fluid and the fluid for cooling and lubrication of the at least one clutch assembly is a hydraulic fluid different from the synthetic fluid.4. The transmission sealed low leak controls system of claim 1 , wherein the first pump defines a high pressure pump operating at a pressure greater than or equal to approximately 100 psi claim 1 , and the second pump defines a low pressure pump operating at a pressure less than or equal to approximately 50 psi.5. The transmission sealed low leak controls system of claim 1 , further including a first reservoir and a second reservoir claim 1 , wherein ...

PROBE INSERTION DEVICE FOR IMPLANTING A PROBE INTO TISSUE

A probe insertion device for implanting a probe into tissue includes a rigid base that selectively attaches to the probe due to a bond between the base and the probe, that provides a structural backbone to the probe, is longitudinally aligned with the probe, and can be adapted to receive a fluid between the base and the probe. The probe insertion device can include a surface covering at least a portion of the base that reduces the bond between the base and the probe in the presence of the fluid. 1. A method of implanting a probe into tissue , comprising the steps:attaching a rigid base to the probe, thereby providing a structural backbone to the probe;inserting at least a portion of the probe into the tissue;decoupling at least a portion of the probe from the base;allowing a fluid to flow between the base and the probe to induce detachment of the base from the probe; andwithdrawing the base from the tissue.2. The method of claim 1 , wherein the step of attaching a base to the probe includes attaching the base to the probe with at least one chemical bond selected from the group consisting of electrostatic forces claim 1 , covalent bonds claim 1 , ionic bonds claim 1 , metallic bonds claim 1 , van der Waals bonds claim 1 , and hydrogen bonds.3. The method of claim 2 , wherein the step of allowing a fluid to flow between the base and the probe includes introducing a fluid that reduces the chemical bond between the base and the probe.4. The method of claim 1 , wherein the step of decoupling at least a portion of the probe from the base includes peeling a portion of the probe from the base.5. A method of implanting a probe into tissue claim 1 , comprising the steps:providing a flexible neural probe including an insertable end that is implantable into the tissue;attaching a rigid base to at least a portion of the probe, thereby providing a structural backbone to the probe;inserting at least a portion of the probe into the tissue;decoupling at least a portion of the probe ...

N-HYDROXYLAMINO-BARBITURIC ACID DERIVATIVES

The present disclosure provides N-hydroxylamino-barbituric acid compounds of formulae (1)-(4), pharmaceutical compositions and kits comprising them, and methods of using such compounds or pharmaceutical compositions. The present disclosure provides methods of using such compounds or pharmaceutical compositions for treating heart failure. 1. An N-hydroxylaminobarbituric acid type compound , wherein said compound has a half-life of greater than about 10 minutes when measured under the conditions described in Example 17 or Example 18 , provided that said compound is not 5-(N-hydroxylamino)-5-ethyl-N ,N-dimethylbarbituric acid or 5-(N-hydroxylamino)-5-(acetyl-O-methyloxime)-N ,N-dimethylbarbituric acid.2. The N-hydroxylaminobarbituric acid type compound of claim 1 , wherein said compound has a half-life from about 10 minutes to about 4000 minutes when measured under the conditions described in Example 17.3. The N-hydroxylaminobarbituric acid type compound of claim 1 , wherein said compound has a half-life from about 15 minutes to about 3900 minutes when measured under the conditions described in Example 17.4. The N-hydroxylaminobarbituric acid type compound of claim 1 , wherein said compound has a half-life from about 10 minutes to about 200 minutes when measured under the conditions described in Example 18.5. The N-hydroxylaminobarbituric acid type compound of claim 1 , wherein said compound has a half-life from about 12 minutes to about 190 minutes when measured under the conditions described in Example 18.6. An N-hydroxylaminobarbituric acid type compound claim 1 , wherein said compound produces a percent yield of HNO greater than about 50% when measured under the conditions described in Example 17 claim 1 , provided that said compound is not 5-(N-hydroxylamino)-5-ethyl-N claim 1 ,N-dimethylbarbituric acid or 5-(N-hydroxylamino)-5-(acetyl-O-methyloxime)-N claim 1 ,N-dimethylbarbituric acid.7. The N-hydroxylaminobarbituric acid type compound of claim 6 , wherein said ...

SYNCHRONIZING DISCONNECT DEVICE

A transmission includes an input member, an output member, a set of four planetary gear sets each having first, second, and third members, a plurality of torque transmitting mechanisms each selectively engageable to interconnect at least one of the first, second, and third members with at least one other of the first, second, third members and a stationary member, and a synchronizer assembly that selectively connects and disconnects one member of one of the planetary gear sets. 1. A transmission comprising:an input member;an output member;first, second, third and fourth planetary gear sets positioned about the output member, each planetary gear set having first, second and third members;six torque transmitting mechanisms each selectively engageable to interconnect at least one of the first, second, and third members with at least one other of the first, second, third members and a stationary member;a synchronizer assembly that selectively connects and disconnects one member of one of the planetary gear sets, andwherein the six torque transmitting mechanisms are selectively engageable in combinations of at least two to establish at least ten forward speed ratios and at least one reverse speed ratio between the input member and the output member.2. The transmission of wherein the synchronizer assembly includes a synchronizer piston that actuates the synchronizer assembly.3. The transmission of wherein the synchronizer assembly includes a synchronizer sleeve claim 2 , synchronizer cone claim 2 , and a synchronizer hub coupled to the synchronizer sleeve and the synchronizer cone claim 2 , wherein the synchronizer piston applies a force to the synchronizer sleeve such that the synchronizer cone engages with a hub associated with the one member of one of the planetary gear sets to synchronize speeds.4. The transmission of wherein the synchronizer assembly includes a dog ring coupled to the hub claim 3 , and wherein the synchronizer sleeve fully engages the hub when the ...

TRANSMISSION WITH BAND CLUTCH

A transmission is provided having a housing, a plurality of planetary gear sets, a structural member, a sprocket member, an annular drum, a band, and an actuator. The sprocket member is rotationally supported by the structural member. The annular drum is adjacent the structural member and is continuously rotationally coupled with a member of the one of the plurality of planetary gear sets. The band circumscribes the annular drum and includes at least a first position and a second position. In the first position the band is substantially separated from the drum and in the second position the band contacts the drum. The actuator selectively positions the band between at least the first position and the second position to transfer torque between the structural member and the annular drum. 1. A transmission comprising:a housing;a plurality of planetary gear sets disposed in the housing and each including a first member, a second member, and a third member;a structural member secured to the housing and including an anchor portion and an actuator portion, wherein the anchor portion defines an anchor bore and the actuator portion defines an actuator cavity;a sprocket member rotationally supported by the structural member;an annular drum adjacent the structural member and including a braking portion that circumscribes one of the plurality of planetary gear sets, wherein the annular drum is continuously rotationally coupled with a member of the one of the plurality of planetary gear sets;a band circumscribing the annular drum and including an anchor portion and an actuating portion, wherein the anchor portion is disposed in the anchor bore of the structural member, and wherein the band includes at least a first position and a second position, and wherein in the first position the band is substantially separated from the drum and in the second position the band contacts the drum; andan actuator including a body and a piston, wherein the body is disposed in the actuator ...

POLYPEPTIDES AND IMMUNIZING COMPOSITIONS CONTAINING GRAM POSITIVE POLYPEPTIDES AND METHODS OF USE

The present invention provides isolated polypeptides isolatable from a spp. Also provided by the present invention are compositions that include one or more of the polypeptides, and methods for making and methods for using the polypeptides. 1. A composition comprising:{'i': Staphylococcus aureus', 'S. aureus, 'two isolated polypeptides having molecular weights of 88 kDa, 55 kDa, 38 kDa, 37 kDa, 36 kDa, 35 kDa, 33 kDa, or a combination thereof, wherein molecular weight is determined by electrophoresis on a sodium dodecyl sulfate-polyacrylamide gel, wherein the polypeptides are isolatable from a when incubated in media comprising an iron chelator and not isolatable when grown in the media without the iron chelator, and wherein the composition protects an animal against challenge with ATCC strain 19636.'}229-. (canceled)30. A method comprising:{'i': 'Staphylococcus aureus', 'administering an effective amount of a composition to a subject at risk of developing lesions caused by infection by , the composition comprisingat least five isolated polypeptides having molecular weights of 88 kDa, 55 kDa, 38 kDa, 37 kDa, 36 kDa, 35 kDa, or 33 kDa, wherein molecular weight is determined by electrophoresis on a sodium dodecyl sulfate-polyacrylamide gel;{'i': 'Staphylococcus aureus', 'wherein the isolated polypeptide having a molecular weight of 88 kDa comprises an amino acid sequence having at least 95% identity to the amino acid sequence of a reference polypeptide, wherein the reference polypeptide has a molecular weight of 88 kDa as determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis, comprises the amino acid sequences depicted in SEQ ID NO:1, SEQ ID NO:2, SEQ ID NO:3, SEQ ID NO:4, SEQ ID NO:5, SEQ ID NO:6, SEQ ID NO:7, SEQ ID NO:9, SEQ ID NO:10, SEQ ID NO:11, SEQ ID NO:12, SEQ ID NO:13, SEQ ID NO:14, SEQ ID NO:15, SEQ ID NO:16, SEQ ID NO:17, SEQ ID NO:19, SEQ ID NO:20, SEQ ID NO:21, SEQ ID NO:22, SEQ ID NO:24, SEQ ID NO:25, SEQ ID NO:26, SEQ ID NO:27, SEQ ID ...

CONTINUOUSLY VARIABLE TRANSMISSION WITH CHAIN OUTPUT

A multi-mode continuously variable transmission in a powertrain of a motor vehicle includes a continuously variable unit connected to a planetary gear set arrangement. The planetary gear set arrangement generally includes two planetary gear sets, two brakes, and one clutch and provides multiple modes of ratio selection between the continuously variable unit and a transmission output member. The transmission output member is connected to a chain driven final having only three axes of rotation. 1. A powertrain for a motor vehicle comprising:a transmission input member;a transmission output member;an intermediate member;a continuously variable unit having a first pulley pair connected for common rotation with the transmission input member, a second pulley pair connected for common rotation with the intermediate member, and an endless member wrapped around the first pulley pair and the second pulley pair;a planetary gear arrangement connected to the intermediate member and to the transmission output member;a plurality of torque transmitting mechanisms interconnected to the planetary gear arrangement;a chain drive connected for common rotation with the transmission output member;a transfer member connected for common rotation with the chain drive; anda final drive planetary gear set connected for common rotation with the transfer member,wherein selective engagement of the plurality of torque transmitting mechanisms and selective movement of the first pulley and second pulley provides two forward ranges of continuous gear ratios between the transmission input member and the transmission output member.2. The powertrain of wherein the planetary gear arrangement includes a nested planetary gear set having a first member claim 1 , a second member claim 1 , a third member claim 1 , and a fourth member claim 1 , wherein each of the first claim 1 , second claim 1 , third claim 1 , and fourth members of the nested planetary gear set are coplanar.3. The powertrain of wherein the ...

QUICK CHANGE CONVEYOR ROLL SLEEVE ASSEMBLY AND METHOD

A quick change conveyor roll assembly for metal or glass processing comprising an inner roll shaft having a rigid and elongated cylindrical surface supported and rotationally driven by an associate rotor mean. At least one removable spool having a cylindrical body with a first diameter, a hollow interior therethrough and a collar rigidly adapted at a first end, the collar having a second diameter whereby the second diameter is greater than the first diameter. At least one removable and replaceable insulated roll sleeve being slidably mounted over at least a portion of said removable spool and abutting said collar, the insulated roll sleeve including at least one layer of an insulation material and a securing means operably adjustable to hold said roll sleeve about said removable spool at a second end in a predetermined location on said inner roll shaft. 1. (canceled)2. (canceled)3. (canceled)4. (canceled)5. (canceled)6. (canceled)7. (canceled)8. (canceled)9. (canceled)10. (canceled)11. (canceled)12. (canceled)13. (canceled)14. (canceled)15. A method of performing a quick change of a conveyor roll assembly comprising:providing an inner shaft in association with a rotation mechanism, said shaft including a first receiving end and a second retaining end;assembling a spool element including an inner metal or ceramic portion and an outer refractory surface, said outer refractory surface being held under compression on said spool, said spool element having a central passage sized to accommodate said inner shaft;providing a means for retaining said spool on said inner shaft;the method further comprising, removing said conveyor roll assembly from the rotation mechanism, releasing said retaining means and removing a spent spool element, slidably mounting a new spool element over the first end of said inner shaft until it engages said retaining end, and replacing said retaining means.16. The method of claim 15 , wherein the inner roll shaft is comprised of steel.17. The ...

Continuously variable transmission with chain output

A continuously variable transmission for a motor vehicle includes an input member, an output member, a first planetary gear set having first, second, and third members, wherein the first member is interconnected with the input member, a brake connected to the second member of the first planetary gear set, a clutch interconnected between one of the first member, second member, and third member of the first planetary gear set and another one of the first member, second member, and third member of the first planetary gear set, a belt and pulley assembly connected to the third member of the first planetary gear set and the output member, a chain drive interconnected to the output member, and a final drive unit interconnected to the chain drive.

COMPOSITIONS PRODUCED USING ENTERIC PATHOGENS AND METHODS OF USE

The present invention provides compositions including polypeptides having the characteristics of polypeptides expressed by a reference microbe such or . Examples of strains that can be used include, for instance, serovar Newport, serovar Enteritidis, serovar Typhimurium, and serovar Dublin. Also provided are compositions including polypeptides having a particular molecular weight and a mass fingerprint that includes polypeptide fragments having a particular set of masses, or polypeptides having an amino acid sequence with at least about 95% identity with an amino acid sequence, wherein the polypeptide has seroreactive activity. The present invention also provides methods of making and methods of using such compositions. 138-. (canceled)39. A composition comprising:{'i': 'E. coli', 'a first isolated iron-regulated polypeptide from strain BEcO157(stx-) having a molecular weight of about 90 kDa as measured following electrophoresis on an SDS-polyacrylamide gel, wherein the first isolated iron-regulated polypeptide, if digested with trypsin, produces polypeptide fragments having m/z values of 629.7±300 parts per million (ppm), 772.6±300 ppm, 831.5±300 ppm, 991.6±300 ppm, 1178.6±300 ppm, 1285.6±300 ppm, 1321.7±300 ppm, 1369.7±300 ppm, 1433.8±300 ppm, 1516.8±300 ppm, 1619.9±300 ppm, 1634.9±300 ppm, 1706.9±300 ppm, 1788.0±300 ppm, 1798.0±300 ppm, 1872.1±300 ppm, 1966.2±300 ppm, 1982.1±300 ppm, 2089.1±300 ppm, 2175.1±300 ppm, 2303.2±300 ppm, 2601.5±300 ppm, 2706.6±300 ppm, 2844.6±300 ppm, 3082.8±300 ppm, and 3213.8±300 ppm;'}{'i': 'E. coli', 'a second isolated iron-regulated polypeptide from strain BEcO157(stx-) having a molecular weight of about 86 kDa as measured following electrophoresis on an SDS-polyacrylamide gel, wherein the second isolated iron-regulated polypeptide, if digested with trypsin, produces polypeptide fragments having m/z values of 976.5±300 ppm, 992.6±300 ppm, 1095.5±300 ppm, 1247.6±300 ppm, 1278.7±300 ppm, 1359.7±300 ppm, 1396.5±300 ppm, 1436.7±300 ppm ...

COMPOSITIONS PRODUCED USING ENTERIC PATHOGENS AND METHODS OF USE

The present invention provides compositions including polypeptides having the characteristics of polypeptides expressed by a reference microbe such or . Examples of strains that can be used include, for instance, serovar Newport, serovar serovar , and serovar Dublin. Also provided are compositions including polypeptides having a particular molecular weight and a mass fingerprint that includes polypeptide fragments having a particular set of masses, or polypeptides having an amino acid sequence with at least about 95% identity with an amino acid sequence, wherein the polypeptide has seroreactive activity. The present invention also provides methods of making and methods of using such compositions. 1. A composition comprising:{'i': 'S. enterica', 'a first isolated polypeptide having a molecular weight of about 82 kDa as measured following electrophoresis on a sodium dodecyl sulfate (SDS)-polyacrylamide gel, wherein the first isolated polypeptide has a mass fingerprint similar to a mass fingerprint of a polypeptide of about 82 kDa obtained from serovar Newport strain MS020508 after growth in low metal conditions;'}{'i': 'S. enterica', 'a second isolated polypeptide having a molecular weight of about 80 kDa as measured following electrophoresis on an SDS-polyacrylamide gel, wherein the second isolated polypeptide has a mass fingerprint similar to a mass fingerprint of a polypeptide of about 80 kDa obtained from serovar Newport strain MS020508 after growth in low metal conditions; and'}{'i': 'S. enterica', 'a third isolated polypeptide having a molecular weight of about 74 kDa as measured following electrophoresis on an SDS-polyacrylamide gel, wherein the third isolated polypeptide has a mass fingerprint similar to a mass fingerprint of a polypeptide of about 74 kDa obtained from serovar Newport strain MS020508 after growth in low metal conditions; and'}{'i': 'S. enterica', 'a fourth isolated polypeptide having a molecular weight of about 65 kDa as measured following ...

COMPOSITIONS PRODUCED USING ENTERIC PATHOGENS AND METHODS OF USE

The present invention provides compositions including polypeptides having the characteristics of polypeptides expressed by a reference microbe such or . Examples of strains that can be used include, for instance, serovar Newport, serovar Enteritidis, serovar , and serovar Dublin. Also provided are compositions including polypeptides having a particular molecular weight and a mass fingerprint that includes polypeptide fragments having a particular set of masses, or polypeptides having an amino acid sequence with at least about 95% identity with an amino acid sequence, wherein the polypeptide has seroreactive activity. The present invention also provides methods of making and methods of using such compositions. 1. A composition comprising:{'i': 'S. enterica', 'a first isolated polypeptide having a molecular weight of about 82 kDa as measured following electrophoresis on a sodium dodecyl sulfate (SDS)-polyacrylamide gel, wherein the first isolated polypeptide has a mass fingerprint similar to a mass fingerprint of a polypeptide of about 82 kDa obtained from serovar Newport strain MS020508 after growth in low metal conditions;'}{'i': 'S. enterica', 'a second isolated polypeptide having a molecular weight of about 80 kDa as measured following electrophoresis on an SDS-polyacrylamide gel, wherein the second isolated polypeptide has a mass fingerprint similar to a mass fingerprint of a polypeptide of about 80 kDa obtained from serovar Newport strain MS020508 after growth in low metal conditions; and'}{'i': 'S. enterica', 'a third isolated polypeptide having a molecular weight of about 74 kDa as measured following electrophoresis on an SDS-polyacrylamide gel, wherein the third isolated polypeptide has a mass fingerprint similar to a mass fingerprint of a polypeptide of about 74 kDa obtained from serovar Newport strain MS020508 after growth in low metal conditions; and'}{'i': 'S. enterica', 'a fourth isolated polypeptide having a molecular weight of about 65 kDa as measured ...

Yersinia spp. Polypeptides and Methods of Use

The present invention provides isolated polypeptides isolatable from a Yersinia spp. Also provided by the present invention are compositions that include one or more of the polypeptides, and methods for making and methods for using the polypeptides.

Yersinia spp. Polypeptides and Methods of Use

The present invention provides isolated polypeptides isolatable from a Yersinia spp. Also provided by the present invention are compositions that include one or more of the polypeptides, and methods for making and methods for using the polypeptides.

AUTOMATED LANE CHANGE SYSTEM WITH STEERING WHEEL ACTIVATION FOR A MOTOR VEHICLE

An automated lane change system for a motor vehicle includes one or more environmental sensors for generating an input signal indicative of a position of an object relative to the motor vehicle, with the object being disposed at a distance from the motor vehicle. The input signal is further indicative of a velocity of the object relative to the motor vehicle. The system further includes a steering wheel sensor generating a gripped signal, in response to a driver gripping a steering wheel. A controller generates an activation signal, in response to the controller receiving the input signal from the environmental sensor and the gripped signal from the steering wheel sensor. An actuator controls the steering wheel, a propulsion mechanism, and a braking mechanism for maneuvering the motor vehicle from a current driving lane to a target driving lane, in response to the actuator receiving the activation signal from the controller. 1. An automated lane change system for a motor vehicle having a steering wheel adapted to be gripped by a driver , the system comprising:{'claim-text': ['a position of an object relative to the motor vehicle, with the object being disposed at a distance from the motor vehicle;', 'a velocity of the object relative to the motor vehicle; and', 'a road geometry including at least a radius of curvature;'], '#text': 'at least one environmental sensor adapted to be mounted to the motor vehicle and generating an input signal indicative of at least one of:'}a steering wheel sensor adapted to be mounted to the motor vehicle and generating a gripped signal in response to the driver gripping the steering wheel;a controller communicating with the at least one environmental sensor and the steering wheel sensor, and the controller generating an activation signal in response to the controller receiving the input signal from the at least one environmental sensor and the gripped signal from the steering wheel sensor; andat least one actuator communicating with ...

MULTI-SPEED TRANSMISSION

A transmission is provided having an input member, an output member, at least four planetary gear sets, a plurality of coupling members and a plurality of torque transmitting devices. Each of the planetary gear sets includes first, second and third members. The torque transmitting devices include clutches and a brake actuatable in combinations of four to establish a plurality of forward gear ratios and at least one reverse gear ratio. 1. A transmission comprising:an input member;an output member;first, second, third and fourth planetary gear sets each having first, second and third members;three interconnecting members continuously interconnecting a member of the first, second, third and fourth planetary gear sets with another member of the first, second, third and fourth planetary gear sets;a grounding member for continuously interconnecting at least one of the members of the planetary gear sets to a stationary member; andsix torque transmitting mechanisms wherein five of the six torque transmitting mechanisms are each selectively engageable to interconnect at least one of the first, second and third members with at least one other of the first, second, third members and a common structural member and wherein one of the six torque transmitting mechanisms are each selectively engageable to interconnect at least one of the first, second and third members with the stationary member, andwherein the six torque transmitting mechanisms are selectively engageable in combinations of at least four to establish a plurality of forward speed ratios and at least one reverse speed ratio between the input member and the output member.2. The transmission of wherein the three interconnecting members further comprises a first interconnecting member continuously interconnecting a first member of the first planetary gear set with a first member of the second planetary gear set claim 1 , a second interconnecting member continuously interconnecting a third member of the second planetary ...

Immunizing compositions and methods of use

The present invention provides compositions including siderophore receptor polypeptides and porins from gram negative microbes, and preferably, lipopolysaccarhide at a concentration of no greater than about 10.0 endotoxin units per milliliter. The present invention also provides methods of making and methods of using such compositions. 1. A composition comprising:at least two siderophore receptor polypeptides (SRPs) isolated from a gram negative microbe;at least two porins isolated from the gram negative microbe; andlipopolysaccharide (LPS) at a concentration of no greater than about 10.0 endotoxin units per milliliter (EU/ml).271-. (canceled) This application claims the benefit of U.S. Provisional Application Ser. No. 60/259,504, filed Jan. 3, 2001, and U.S. Provisional Application Ser. No. 60/262,896, filed Jan. 19, 2001 which is incorporated by reference herein.The economic impact of infectious diseases in food animal production is well appreciated. Infectious diseases reduce profits, increase production costs, and endanger the overall wholesomeness of the food products, as well as effect the performance, health and welfare of the animal. This disease status can reduce the yield and quality of milk resulting in great economic loss to the dairymen. In some cases, infectious microbial diseases can cause morbidity and mortality of newborn, young (e.g., replacement stock) or adult animals.The agricultural industry presently relies on antibiotic therapy and vaccines to decrease losses caused by clinical and subclinical infectious diseases, including gastrointestinal disease, respiratory disease, and systemic disease. However, for some conditions, antibiotics are ineffective, may prolong the condition, or induce a carrier state. Vaccines have often proven to be an effective means of controlling infectious diseases, but, concerns relating to adverse effects or lack of protection against multiple microbes have been a major drawback to current vaccines. For instance, ...

Yersinia spp. Polypeptides and Methods of Use

The present invention provides isolated polypeptides isolatable from a spp. Also provided by the present invention are compositions that include one or more of the polypeptides, and methods for making and methods for using the polypeptides. 128-. (canceled)29. A method for treating in infection in a subject comprising:{'i': 'Yersinia', 'administering an effective amount of a composition to a subject having or at risk of having an infection caused by a spp., wherein the composition comprises{'i': Yersinia pestis', 'Y. pestis, 'two isolated polypeptides having molecular weights of 94 kDa, 88 kDa, 77 kDa, 73 kDa, or 64 kDa, or a combination thereof, and two isolated polypeptides having molecular weights of 46 kDa, 37 kDa, or a combination thereof, wherein molecular weight is determined by electrophoresis on a sodium dodecyl sulfate-polyacrylamide gel, wherein the polypeptides having a molecular weight of 94 kDa, 88 kDa, 77 kDa, 73 kDa, or 64 kDa are isolatable from a when incubated in media comprising an iron chelator and not isolatable when grown in the media without the iron chelator, and wherein the composition protects a mouse against challenge with strain KIM6+,'}{'i': Yersinia pestis', 'Y. pestis, 'two isolated polypeptides having molecular weights of 94 kDa, 88 kDa, 77 kDa, 73 kDa, or 64 kDa, or a combination thereof, and two isolated polypeptides having molecular weights of 254 kDa, 46 kDa, 37 kDa, 36 kDa, 31 kDa, 28 kDa, 20 kDa, or a combination thereof, wherein molecular weight is determined by electrophoresis on a sodium dodecyl sulfate-polyacrylamide gel, wherein the polypeptides having a molecular weight of 94 kDa, 88 kDa, 77 kDa, 73 kDa, or 64 kDa, are isolatable from a when incubated in media comprising an iron chelator and not isolatable when grown in the media without the iron chelator, and wherein the composition protects a mouse against challenge with strain KIM6+, or'}{'i': Yersinia pestis', 'Y. pestis, 'isolated polypeptides having molecular ...

Computing device resource management

The disclosed technology adjusts hardware settings to map preferences consistently of a user experience across multiple hardware devices, despite there being different hardware capabilities and performance parameters among the different devices. A hardware settings translation engine receives a reference hardware setting of a reference computing device, a set of reference hardware performance parameter values, and a set of target hardware performance parameter values. The hardware settings translation engine then maps the set of target hardware performance parameter values to the set of reference hardware performance parameter values to yield a hardware adjustment map. The hardware settings translation engine determines the target hardware setting based on the reference hardware adjustment map and the reference hardware setting. The hardware settings translation engine sets the target hardware to the target hardware setting.

SOFTWARE RESOURCE MANAGEMENT

The disclosed technology provides a multiapplication workflow engine. The multiapplication workflow engine includes a request processing engine, a multiapplication workflow configuration manager, and a multiapplication workflow execution engine. The request processing engine is configured to receive instructions to execute a multiapplication workflow. The multiapplication workflow defines two or more operations and provides a functionality definition corresponding to each of the operations and an interface definition corresponding to each of the operations. The interface defintions of each operation are defined so that operations that execute successively have compatible interface definitions. The multiapplication workflow configuration manager is configured to instatiate one or more applications that satisfy the interface definition and the functionality definition for each operation in a protected execution environment, where the applications are configured to communicate via compatible interfaces. The multiapplication workflow engine is configured to execute the multiapplication workflow in the protected execution environment. 1. A multiapplication workflow engine comprising:one or more computing processors;a request processing engine configured to receive instruction to execute a multiapplication workflow via the one or more computing processors, the multiapplication workflow defining two or more operations and providing a functionality definition corresponding to each of the two or more operations and an interface definition corresponding to each of the two or more operations, the interface definition corresponding to each operation being defined such that operations that are executed successively have compatible interface definitions;a multiapplication workflow configuration manager configured to instantiate one or more applications executed by the one or more computing processors, the one or more applications satisfying the interface definition and ...

HYBRID MANUAL TRANSMISSION

A vehicle powertrain includes a manual transmission with an input shaft including a plurality of input gears and at least one main shaft including a plurality of driven gears engaged with the input gears. An engine includes a drive shaft drivingly connected to the input shaft via an engine disconnect clutch and a launch clutch. An electric motor is non-concentric with the input shaft and is drivingly connected to the input shaft via the launch clutch. 1. A vehicle powertrain , comprising:a manual transmission with an input shaft including a plurality of input gears and at least one main shaft including a plurality of driven gears engaged with the input gears;an engine having a drive shaft drivingly connected to the input shaft via a first clutch and a second clutch; andan electric motor drivingly connected to the input shaft via the second clutch.2. The vehicle powertrain according to claim 1 , wherein the electric motor is non-concentric with the input shaft.3. The vehicle powertrain according to claim 2 , wherein the electric motor is drivingly connected to the input shaft via a belt and pulley system.4. The vehicle powertrain according to claim 3 , wherein the belt and pulley system includes a drive pulley connected to a drive shaft of the electric motor and a driven pulley connected to a primary input shaft concentric with the input shaft of the transmission.5. The vehicle powertrain according to wherein the primary input shaft is selectively connected to the input shaft of the manual transmission via the second clutch.6. The vehicle powertrain according to claim 2 , wherein the electric motor is drivingly connected to the input shaft via a sprocket and chain system.7. The vehicle powertrain according to claim 6 , wherein the sprocket and chain system includes a drive sprocket connected to a drive shaft of the electric motor and a driven sprocket connected to a primary input shaft concentric with the input shaft of the transmission.8. The vehicle powertrain ...

N-SUBSTITUTED HYDROXYLAMINE DERIVATIVES WITH CARBON-BASED LEAVING GROUPS

The disclosed subject matter provides certain N-substituted hydroxylamine derivative compounds, pharmaceutical compositions and kits comprising such compounds, and methods of using such compounds or pharmaceutical compositions. In particular, the disclosed subject matter provides methods of using such compounds or pharmaceutical compositions for treating, preventing, or delaying the onset and/or development of a disease or condition. In some embodiments, the disease or condition is selected from cardiovascular diseases, ischemia, reperfusion injury, cancerous disease, pulmonary hypertension and conditions responsive to nitroxyl therapy. 23.-. (canceled)4. The compound of claim 1 , wherein R is C-Calkyl claim 1 , wherein the alkyl is unsubstituted or substituted with one or more substituents.5. The compound of claim 1 , wherein R is C-Calkyl.6. The compound of claim 1 , wherein R is —C(═NOR)R.7. The compound of claim 1 , wherein R is —C(═NOR)R; and Rand Rare independently C-Calkyl.8. The compound of any one of claim 1 , and to claim 1 , wherein X and Z are each —O—.9. The compound of any one of claim 1 , and to claim 1 , wherein X and Z are each —NR—.10. The compound of any one of claim 1 , and to claim 1 , wherein X and Z are each —NR—; and Ris C-Calkyl.11. The compound of any one of claim 1 , and to claim 1 , wherein Y is —CRR—.12. The compound of any one of claim 1 , and to claim 1 , wherein Y is —C(═O)—.1319.-. (canceled)21. A pharmaceutical composition comprising:{'claim-ref': {'@idref': 'CLM-00001', 'claim 1'}, 'a compound of ; and'}a pharmaceutically acceptable excipient.22. A method of treating a disease or condition selected from cardiovascular diseases claim 1 , ischemia claim 1 , reperfusion injury claim 1 , cancerous disease claim 1 , pulmonary hypertension and conditions responsive to nitroxyl therapy claim 1 , comprising administering a compound of to a subject in need thereof.23. A method of modulating in vivo nitroxyl levels claim 1 , comprising ...

PLANETARY AXIS TRANSFER GEARBOX

A motor vehicle planetary axis transfer gearbox system includes a connective housing connecting an engine to a transmission of a motor vehicle with the transmission being positioned forward of the engine. An axis of an engine output shaft is oriented substantially parallel to an axis of a transmission input shaft. Both the axis of the engine output shaft and the axis of the transmission input shaft are oriented substantially perpendicular to a central axis of the motor vehicle. A planetary gear set is connected to one of the engine output shaft or the transmission input shaft acting to reverse a direction of rotation of either the engine output shaft or the transmission input shaft to match a direction of rotation of both the engine output shaft and the transmission input shaft. A drive chain connects the engine output shaft to the transmission input shaft. 1. A motor vehicle planetary axis transfer gearbox system , comprising:a connective housing connecting an engine to a transmission of a motor vehicle with the transmission being positioned forward of the engine;an axis of an engine output shaft being oriented substantially parallel to an axis of a transmission input shaft, both the axis of the engine output shaft and the axis of the transmission input shaft being oriented substantially perpendicular to a central axis of the motor vehicle; anda planetary gear set connected to one of the engine output shaft or the transmission input shaft acting to reverse a direction of rotation of either the engine output shaft or the transmission input shaft to match a direction of rotation of both the engine output shaft and the transmission input shaft.2. The motor vehicle planetary axis transfer gearbox system of claim 1 , further including a drive chain positioned within the connective housing claim 1 , the drive chain connecting the engine output shaft to the transmission input shaft.3. The motor vehicle planetary axis transfer gearbox system of claim 2 , further including: ...

System and method for tracking brain states during administration of anesthesia

A method and system for determining the state of a patients brain under anesthesia. The present invention recognizes that anesthesia compounds induce different signatures in physiological characteristics of the patient under anesthesia and aids interpretation of physiological characteristics and signatures therein based on a selected anesthesia compound. The present invention aids the monitoring and/or interpreting of the physiological characteristics to a state of the patient's brain.

PASSIVE OPENING LOW LOSS CLUTCH PACK

A passive opening transmission clutch system includes a backing plate having multiple tab slots, each of the tab slots having a tapered wall. A first reaction plate has multiple first tapered spline teeth oriented transverse to a plane of the first reaction plate. The first tapered spline teeth are positioned at least partially in individual ones of the tab slots in a clutch disengaged condition. The first tapered spline teeth when displaced further into the tab slots and toward the backing plate define a clutch engaged condition. A first friction plate is in frictional contact with the first reaction plate in the clutch engaged condition, the first friction plate when rotated generating a rotational force on the first reaction plate. The rotational force acts against the first tapered spline teeth to induce the first reaction plate to slidably move away from the backing plate. 1. A passive opening transmission clutch system , comprising:a backing plate having multiple tab slots;a first reaction plate having multiple first tapered spline teeth, individual ones of the first tapered spline teeth positioned at least partially in individual ones of the tab slots in a clutch disengaged condition; anda first friction plate in frictional contact with the first reaction plate when the first tapered spline teeth are displaced further into the tab slots and toward the backing plate defining a clutch engaged condition;the first friction plate when rotated generating a rotational force on the first reaction plate;wherein the rotational force acts against the first tapered spline teeth to induce the first reaction plate to slidably move away from the backing plate.2. The passive opening transmission clutch system of claim 1 , further including a second reaction plate having multiple second tapered spline teeth each positioned partially in one of the tab slots and displaced further into the tab slots in the clutch engaged condition.3. The passive opening transmission clutch ...

TORQUE TRANSFERRING CLUTCH SEPARATION

A torque transferring transmission-drive system includes a first friction surface. A second friction surface is directed toward the first friction surface. A reaction plate is positioned between the first friction surface and the second friction surface. A piston is actuated by a fluid pressure to displace the first friction surface toward the second friction surface, frictionally engaging the reaction plate between the first friction surface and the second friction surface. At least one strap spring in a clutch engaged condition elastically compresses to allow the reaction plate to be frictionally engaged between the first friction surface and the second friction surface, and in a clutch disengaged condition the at least one strap spring elastically expands to create a clearance between the reaction plate and each of the first friction surface and the second friction surface. 1. A torque transferring transmission-drive system , comprising:a first friction plate having a first friction surface;a second friction plate having a second friction surface directed toward the first friction surface;a reaction plate positioned between the first friction surface and the second friction surface; andat least one strap spring in a clutch engaged condition elastically compresses allowing the reaction plate to be frictionally engaged between the first friction surface and the second friction surface, and in a clutch disengaged condition the at least one strap spring elastically expands creating a clearance between the reaction plate and each of the first friction surface and the second friction surface.2. The system of claim 1 , wherein the at least one strap spring is connected at a first end to the second friction plate and is connected at a second end to the first friction plate such that the at least one strap spring joins the first friction plate to the second friction plate.3. The system of claim 2 , wherein the second friction plate defines a double sided friction plate ...

Methods and apparatuses for determining cable resistance

In one embodiment, a method is provided. The method comprises: setting a first voltage level provided to a cable; operating a radio, coupled to the cable, with constant power consumption; measuring a first current level provided to the cable; setting a second voltage level provided to the cable; measuring a second current level provided to the cable; and determining a first resistance of the cable using the first and second voltage and current levels.

AUTOMATIC TRANSMISSION WITH INTEGRATED ENGINE STARTER, REMOTE MOUNTED PUMP AND DRIVE SYSTEM

An automatic transmission includes a plurality of planetary gear assemblies, an integrated starter, a remote mounted hydraulic pump and a common drive system. An input shaft of the automatic transmission is coupled to and drives a ring (spur) gear. In one portion of the automatic transmission, a starter motor is disposed and includes gear teeth on an output shaft that engage a pinion gear that, in turn, engages the input shaft ring gear. In another portion of the automatic transmission, preferably the lower portion, an off axis hydraulic pump includes a drive shaft and driven gear which also engages the input shaft ring gear. 1. A multiple speed automatic transmission comprising , in combination ,an input member,at least one input clutch having an input coupled to said input member and an output,a plurality of planetary gear assemblies, at least three of said planetary gear assemblies having at least three members,one of said plurality of planetary gear assemblies having one of said at least three members coupled to said output of said clutch and including a gear train engaging a starter motor and a hydraulic pump, andan output member coupled to one of said at least three members of another one of said plurality of planetary gear assemblies.2. The multiple speed automatic transmission of further including a plurality of torque transmitting devices selectively engageable to connect: one of said members of said one of said plurality of planetary gear assemblies to ground; another of said members of said one of said plurality of planetary gear assemblies and one of said members of yet another of said plurality of planetary gear assemblies to ground; another of said members of said yet another of said plurality of planetary gear assemblies to ground; and one of said members of another of said plurality of planetary gear assemblies and one of said members of still another of said plurality of planetary gear assemblies to ground.3. The multiple speed automatic ...

MULTI-SPEED DUAL CLUTCH TRANSMISSION

A transmission is connectable to an input member and includes an output transfer gear, first and second transmission input shaft members, first and second countershaft members, a plurality of co-planar gear sets, and a plurality of torque transmitting devices. The torque transmitting devices include a plurality of synchronizer assemblies and a dual clutch assembly. The transmission is operable to provide at least one reverse speed ratio and a plurality of forward speed ratios between the input member and the output member. 1. A transmission comprising:a transmission housing;a dual clutch assembly having a first clutch, a second clutch and a clutch housing connectable to an engine output member, wherein the clutch housing is rotationally supported within the transmission housing;a first, second, third and fourth gear set, wherein the first gear set includes a first gear, a second gear, a third gear and an idler gear, wherein the first gear is in mesh with the second gear and the second gear is in mesh with the idler gear and the idler gear is in mesh with the third gear, the second gear set includes a first gear in mesh with a second gear and a third gear, the third gear set includes a first gear in mesh with a second gear and a third gear, the fourth gear set includes a first gear in mesh with a second gear and a third gear in mesh with the second gear set;a first transmission input member rotatably supported in the transmission housing and wherein the first gear of the first gear set and the first gear of the second gear set are rotatably fixed for common rotation with the first transmission input member and wherein the selective engagement of the first clutch of the dual clutch assembly transfers torque from the clutch housing to the first transmission input member;a second transmission input member rotatably supported in the transmission housing and wherein the first gear of the third gear set and the first gear of the fourth gear set are rotatably fixed for ...

TRANSMISSION-INTEGRATED ELECTROMECHANICAL DEVICE

A transmission assembly for use in a motor vehicle is provided. The transmission assembly has a case for housing components of the transmission and an electromechanical device operable to convert mechanical energy to electrical energy. The electromechanical device is disposed within the transmission case. The case may have a main housing portion and a bell housing portion, with the electromechanical device housed in the main housing portion, in some variations. A transmission shaft may be rotatably supported within the case and configured to be connected to an engine of the motor vehicle. A connecting device may continuously interconnect the electromechanical device with the transmission shaft. 1. A transmission assembly for use in a motor vehicle , the transmission assembly comprising:a transmission having a case for housing components of the transmission;a transmission shaft rotatably supported within the case, the transmission shaft configured to be connected to an engine of the motor vehicle;an electromechanical device disposed in the case, the electromechanical device operable to convert mechanical energy to electrical energy; anda connecting device continuously interconnecting the electromechanical device with the transmission shaft.2. The transmission assembly of wherein the electromechanical device is operable to start an engine of the motor vehicle claim 1 , the transmission shaft being operable as an input to the transmission and as an output from the transmission to the engine.3. The transmission assembly of claim 2 , further comprising a rotatable device shaft extending from the electromechanical device claim 2 , wherein the connecting device is a chain that connects the device shaft to the transmission shaft.4. The transmission assembly of claim 2 , wherein the electromechanical device operates as an alternator claim 2 , an engine starter claim 2 , and a regenerative braking generator.5. The transmission assembly of claim 3 , wherein the ...

TRANSMISSION WITH DOG CLUTCH BRAKE

A transmission is provided having a housing, a plurality of planetary gear sets, a structural member, a sprocket member, a first dog clutch member, a second dog clutch member, and a biasing member. The structural member is secured to the housing and includes a plurality of splines and defines a cavity. The sprocket member is rotationally supported by the structural member. The first dog clutch member is disposed in the cavity of the structural member and includes splines and dogteeth. The splines are engaged with the splines of the structural member. The second dog clutch member includes dogteeth that are aligned with the dogteeth of the first dog clutch member. The biasing member is disposed between the structural member and the first dog clutch member. 1. A transmission comprising:a housing;a plurality of planetary gear sets disposed in the housing and each including a first member, a second member, and a third member;a structural member secured to the housing, wherein the structural member includes a plurality of splines and defines a cavity;a sprocket member rotationally supported by the structural member;a first dog clutch member disposed in the cavity of the structural member, the first dog clutch including a plurality of splines and a plurality of dogteeth, wherein the plurality of splines are engaged with the plurality of splines of the structural member;a second dog clutch member disposed substantially radially inward of the second dog clutch member and having an axis of rotation, the second dog clutch member including a plurality of dogteeth that are aligned with the dogteeth of the first dog clutch member at a common radial distance from the axis of rotation of the second dog clutch member, and wherein the second dog clutch member is rotationally coupled with at least one of the first, second, third members of at least one of the plurality of planetary gear sets; anda biasing member disposed between the structural member and the first dog clutch member to ...

TWIN AXIS TWIN-MODE CONTINUOUSLY VARIABLE TRANSMISSION

A continuously variable transmission (CVT) for a motor vehicle includes a transmission input shaft rotatably connected to an engine by a torque converter, the transmission input shaft defining a first CVT axis. A continuously variable unit connected for rotation by the transmission input shaft includes a first pulley assembly, a second pulley assembly, and a flexible member wrapped around the first pulley assembly and the second pulley assembly. A two mode transfer gear assembly is connected to the second pulley assembly and is coaxially aligned for rotation on a second CVT axis. A clutch assembly having at least one clutch is connected to the transfer gear assembly. A final drive unit connected to the transfer gear assembly is co-axially aligned with respect to the second CVT axis. 1. A continuously variable transmission (CVT) for a motor vehicle , comprising:a torque converter connected to an engine, the torque converter rotating with respect to a first CVT axis;a first pulley assembly having a first pulley hub coaxially aligned with the first CVT axis and rotated by the torque converter;a second pulley assembly aligned on a second CVT axis;a flexible member coupling the first pulley assembly to the second pulley assembly; anda final drive unit co-axially aligned with respect to the second CVT axis and rotated by the second pulley assembly.2. The continuously variable transmission (CVT) of claim 1 , further including a two mode transfer gear assembly connected to the second pulley assembly and coaxially aligned for rotation on the second CVT axis claim 1 , the two mode transfer gear assembly including a planetary gear assembly and a clutch assembly having at least one clutch connected to the planetary gear assembly.3. The continuously variable transmission (CVT) of claim 2 , wherein the planetary gear assembly includes:a first planetary gear set having a sun gear and a ring gear;a second planetary gear set having a sun gear; anda common planet carrier member ...

BLUETOOTH IDENTITY BINDING FOR VOLUME CONTROL

Techniques for controlling audio volume output by a paired device are described. A first notification indicative of a change to a first volume by a first audio output device generated. The first notification comprises a first identifier of the first audio output device. A first record indicative of a volume of audio is stored. The first record is indexed by the first identifier. A second notification indicative of an audio stream being redirected from the first audio output device to a second audio output device is generated. The second notification comprises a second identifier of the second audio output device. A second record indicative of a second volume of audio output by the second device is retrieved. The second record is retrieved based at least in part on the second identifier. The second audio output device outputs audio at the second volume, based at least in part on the second record. 1. A system comprising a processor and memory , the memory storing computer-executable instructions that , when executed by the processor , cause the system to perform operations comprising:store a plurality of volume notifications, each volume notification comprising an identifier of a Bluetooth audio output device and data indicative of an output level associated with the Bluetooth audio output device;receive an endpoint change notification that is generated in response to an audio stream being redirected from a first Bluetooth audio output device to a second Bluetooth audio output device, the endpoint change notification comprising an identifier of the second Bluetooth audio output device;in response to receiving the endpoint change notification, retrieve a volume notification associated with the second Bluetooth audio output device, the retrieved volume notification identified based at least in part on the identifier contained in the endpoint change notification; andcause the second Bluetooth audio output device to output audio at an output level identified in the ...

POLYPEPTIDES AND IMMUNIZING COMPOSITIONS CONTAINING GRAM POSITIVE POLYPEPTIDES AND METHODS OF USE

The present invention provides isolated polypeptides isolatable from a spp. Also provided by the present invention are compositions that include one or more of the polypeptides, and methods for making and methods for using the polypeptides. 1. A composition comprising:{'i': Staphylococcus aureus', 'S. aureus, 'two isolated polypeptides having molecular weights of 88 kDa, 55 kDa, 38 kDa, 37 kDa, 36 kDa, 35 kDa, 33 kDa, or a combination thereof, wherein molecular weight is determined by electrophoresis on a sodium dodecyl sulfate-polyacrylamide gel, wherein the polypeptides are isolatable from a when incubated in media comprising an iron chelator and not isolatable when grown in the media without the iron chelator, and wherein the composition protects an animal against challenge with ATCC strain 19636.'}229-. (canceled) This application claims the benefit of U.S. Provisional Application Ser. No. 60/652,843, filed Feb. 14, 2005, which is incorporated by reference herein.Gram-positive bacteria are a remarkably diverse group of organisms that cause a variety of diseases in both humans and animals. Some of the pathogens recognized as important in human and/or animal health include bacteria belonging to the families of Corynebacteriaceae, Enterococcacae, Micrococcaceae, Mycobacteriaceae, Nocardiaceae, and Peptococcaceae, which include such bacterial species as spp., spp., spp., spp., spp. spp., spp., spp., spp., spp., spp., spp., spp., and spp. These pathogens cause a multitude of clinical manifestations in many different animal species. The treatment for such infections has historically been antibiotics that attack the common structures and functions of gram-positive organisms. However, many of the more ubiquitous gram-positive organisms have developed resistance to several classes of antibiotics, making treatment of infections difficult. The widespread use of antibiotics in the treatment of bacterial diseases in both humans and food production animals is likely a major ...

Use of Eductor for Liquid Disposal from Vessel

A system for the processing of a hydrocarbon flare gas. An input gas stream contains a gas component and a liquid component. A knock-out drum separates the gas component from the liquid component. An eductor has a motive inlet, a suction inlet, and a discharge outlet. The separated liquid component is introduced into the suction inlet of the eductor. A high-pressure gas stream is introduced into the motive inlet of the eductor. The high-pressure gas stream has a pressure sufficient to draw the separated liquid component from the knock-out drum and through the discharge outlet. 1. A system for the processing of a hydrocarbon flare gas , comprising:an input gas stream containing a gas component and a liquid component;a knock-out drum that separates the gas component from the liquid component;an eductor having a motive inlet, a suction inlet, and a discharge outlet;wherein the separated liquid component is introduced into the suction inlet of the eductor; anda high-pressure gas stream introduced into the motive inlet of the eductor, the high-pressure gas stream having a pressure sufficient to draw the separated liquid component from the knock-out drum and through the discharge outlet.2. The system of claim 1 , wherein the knock-out drum has a boot or sump claim 1 , and wherein the separated liquid component is drawn from the boot or sump to the suction inlet of the eductor.3. The system of claim 1 , wherein the high-pressure gas stream is a defrost gas stream.4. The system of claim 1 , wherein the high-pressure gas stream has a pressure of about 100 psig and the input gas stream has a pressure between 1-2 psig.5. The system of claim 1 , further comprising a dry flare that flares the gas component of the input gas stream after the liquid component has been separated therefrom in the knock-out drum.6. A cryogenic or cold gas processing system claim 1 , comprising:an input gas stream containing a gas component and a liquid component;a knock-out drum that separates the gas ...

MULTI-SPEED TRANSMISSION WITH A SERIES DISCONNECT CLUTCH

A transmission is provided having an input member, an output member, a plurality of planetary gear sets, a plurality of coupling members and a plurality of torque transmitting devices. One of the plurality of torque transmitting devices is an integrated friction launch clutch. A disconnect clutch is in series relationship with the launch clutch and is configured to disconnect the launch clutch from at least one of the plurality of planetary gear sets. The torque transmitting devices include clutches and brakes actuatable in combinations of two to establish at least ten forward gear ratios and one reverse gear ratio. 1. A powertrain comprising:an engine; and an input member connected to the engine;', 'an output member;', 'a plurality of planetary gear sets connected between the input member and the output member;, 'a transmission includinga launch clutch connected to one of the plurality of planetary gear sets, wherein the launch clutch is configured to engage during a first gear and a reverse gear, wherein the first gear provides the largest gear ratio of any other forward gear provided by the transmission; anda disconnect clutch connected between the launch clutch and the one of the plurality of planetary gear sets, wherein the disconnect clutch is configured to couple the launch clutch with the one of the plurality of planetary gear sets when the launch clutch is engaged and to disconnect the launch clutch with the one of the plurality of planetary gear sets when the launch clutch is not engaged.2. The powertrain of wherein the launch clutch includes a housing and a hub claim 1 , and wherein the disconnect clutch is connected to the hub of the launch clutch and a member connected to the one of the planetary gear sets.3. The powertrain of wherein the input member of the transmission is not connected to a hydrodynamic starting device disposed between the engine and the input member.4. The powertrain of wherein the transmission is a ten-speed transmission.5. The ...

ADZER BIT WITH CUTTING SEGMENTS

An adzer bit includes a support member that defines a through hole that is configured to receive a fastener. The support member includes a cutting segment cap portion and a base portion. The support member also defines an annular slot that is axially disposed between the cutting segment cap portion and the base portion. A plurality of cutting segments are received and secured in the annular slot. The material of the plurality of cutting segments is harder than the material of the support member. 1. An adzer bit , comprising:a base member;a cutting segment cap coupled to the base member and formed of a first material; anda plurality of cutting segments axially disposed between the base member and the cutting segment cap and formed of a second material, the second material being harder than the first material.2. The adzer bit of wherein the plurality of cutting segments forms an annulus.3. The adzer bit of wherein a segment support boss is axially disposed between the base member and the cutting segment cap and the plurality of cutting segments being peripherally disposed around the segment support boss.4. The adzer bit of wherein one of the plurality of cutting segments is abutted to an adjacent cutting segment.5. The adzer bit of wherein the second material comprises tungsten carbide.6. The adzer bit of wherein the base member and the cutting segment cap define a through hole configured to receive a fastener to couple the adzer bit to an adzer head.7. The adzer bit of wherein the first material comprises steel.8. The adzer bit of wherein the plurality of cutting segments comprises four cutting segments.9. The adzer bit of wherein each one of the plurality of cutting segments is defined by an outer arcuate surface claim 1 , an inner arcuate surface claim 1 , and a plurality of opposed end surfaces claim 1 , an end surface of one cutting segment abutting an end surface of an adjacent cutting segment.10. The adzer bit of wherein the plurality of cutting segments ...

METHODS AND EQUIPMENT FOR REDUCING POWER LOSS IN CELLULAR SYSTEMS

A method is provided. The method comprises determining configuration data; wherein the configuration data comprises a resistance of a bypass circuit coupled between a remote radio head and a power cable; using the configuration data, determining the resistance of the power cable coupling a programmable power supply to the remote radio head mounted on a mounting structure, comprising: entering a calibration mode; setting an output voltage of the programmable power supply; measuring an output current of the programmable power supply; storing the output current; and determining the cable resistance; and storing the resistance of the power cable. 1. A system comprising:a mounting structure;an antenna mounted on the mounting structure;a remote radio head mounted on the mounting structure;a programmable power supply;a processing system;a bypass circuit mounted on the mounting structure proximate to the remote radio head, and coupled to the remote radio head;a power cable, having a first conductor and a second conductor, coupled between the programmable power supply and the bypass circuit; an input/output interface circuit coupled to the first conductor and the second conductor;', 'a first switch coupled between the first conductor and the second conductor;, 'wherein the bypass circuit compriseswherein the input/output interface circuit is coupled to the first switch, configured to measure a voltage across the first conductor and the second conductor of the power cable, and configured to control a position of the first switch; andthe processing system is configured to receive and store the measured voltage across the first conductor and the second conductor when the first switch is closed, and configured to determine a resistance of the power cable.2. The system of claim 1 , wherein the bypass circuit further comprises a second switch claim 1 , coupled between the first switch and the remote radio head claim 1 , and in series with the first conductor;wherein the input/ ...

O-SUBSTITUTED HYDROXAMIC ACIDS

O-substituted hydroxamic acids with carbon-based leaving groups as HNO donors are disclosed. Pharmaceutical compositions and kits comprising such compounds, and methods of using such compounds or pharmaceutical compositions also are disclosed. 2. The compound of claim 1 , wherein the compound is of formula (I).3. The compound of claim 1 , wherein the compound is of formula (II).4. The compound of claim 1 , wherein the compound is of formula (III).5. The compound of claim 2 , wherein R is selected from the group consisting of hydrogen claim 2 , (C-C)alkyl claim 2 , (C-C)aryl and (5- or 6-membered)heteroaryl claim 2 , wherein said alkyl claim 2 , heteroaryl and aryl are unsubstituted or substituted with 1 claim 2 , 2 or 3 substituent(s).68.-. (canceled)9. The compound of claim 2 , wherein Ris selected from the group consisting of (C-C)alkyl claim 2 , (C-C)perhaloalkyl claim 2 , (C-C)alkoxy claim 2 , (C-C)aryl claim 2 , (5- or 6-membered)heteroaryl claim 2 , phenylsulfanyl claim 2 , phenylsulfonyl claim 2 , phenylsulfinyl and (C-C)cycloalkyl claim 2 , wherein said alkyl claim 2 , perhaloalkyl claim 2 , alkoxy claim 2 , aryl claim 2 , heteroaryl claim 2 , phenylsulfanyl claim 2 , phenylsulfonyl claim 2 , phenylsulfinyl and cycloalkyl are unsubstituted or substituted with 1 claim 2 , 2 or 3 substituent(s).1011.-. (canceled)12. The compound of claim 3 , wherein Xand Xare independently O or NR.1314.-. (canceled)15. The compound of claim 4 , wherein claim 4 , Z is O or S.1617.-. (canceled)18. The compound of claim 3 , wherein Y is C(═O) or CRR.1920.-. (canceled)21. The compound of claim 1 , wherein Ris selected from the group consisting of (C-C)alkyl claim 1 , —C(═O)R claim 1 , —C(═S)R claim 1 , C(═NR)R claim 1 , —C(═NOR)R claim 1 , (5- or 6-membered)heteroaryl and (C-C)aryl claim 1 , wherein said aryl is unsubstituted or substituted with 1 claim 1 , 2 or 3 substituent(s).2224.-. (canceled)25. The compound of claim 1 , wherein Ris selected from the group consisting of (C-C) ...

POLYPEPTIDES AND IMMUNIZING COMPOSITIONS CONTAINING GRAM POSITIVE POLYPEPTIDES AND METHODS OF USE

The present invention provides isolated polypeptides isolatable from a spp. Also provided by the present invention are compositions that include one or more of the polypeptides, and methods for making and methods for using the polypeptides. 1. A composition comprising:{'i': Staphylococcus aureus', 'S. aureus, 'two isolated polypeptides having molecular weights of 88 kDa, 55 kDa, 38 kDa, 37 kDa, 36 kDa, 35 kDa, 33 kDa, or a combination thereof, wherein molecular weight is determined by electrophoresis on a sodium dodecyl sulfate-polyacrylamide gel, wherein the polypeptides are isolatable from a when incubated in media comprising an iron chelator and not isolatable when grown in the media without the iron chelator, and wherein the composition protects an animal against challenge with ATCC strain 19636.'}229-. (canceled) This application claims the benefit of U.S. Provisional Application Ser. No. 60/652,843, filed Feb. 14, 2005, which is incorporated by reference herein.Gram-positive bacteria are a remarkably diverse group of organisms that cause a variety of diseases in both humans and animals.Some of the pathogens recognized as important in human and/or animal health include bacteria belonging to the families of Corynebacteriaceae, Enterococcacae, Micrococcaceae, Mycobacteriaceae, Nocardiaceae, and Peptococcaceae, which include such bacterial species as spp., spp., spp., spp., spp., spp., spp., spp., spp., spp., spp., spp., spp., and spp. These pathogens cause a multitude of clinical manifestations in many different animal species. The treatment for such infections has historically been antibiotics that attack the common structures and functions of gram-positive organisms. However, many of the more ubiquitous gram-positive organisms have developed resistance to several classes of antibiotics, making treatment of infections difficult. The widespread use of antibiotics in the treatment of bacterial diseases in both humans and food production animals is likely a major ...

POWER SOURCE SELECTION

A method for selecting a power source for a load is provided. The method includes monitoring the primary power source, when the primary power source is providing power to the load, determining if a condition of the primary power source crosses a first threshold, when the condition crosses the first threshold, turning on a first power field effect transistor to couple a back-up power source to the load through a second power field effect transistor, when the primary power source is not providing power to the load, determining if a condition of the primary power source crosses a second threshold, and when the condition crosses the second threshold, switching off the first power field effect transistor to couple the primary power source to the load through a third power field effect transistor. 1. A circuit for selecting between a primary power source and a back-up power source , the circuit comprising:a first port configured to be coupled to a primary power source;a second port configured to be coupled to a back-up power source;a third port configured to be coupled to provide power to a load;first and second power field effect transistors (FET) coupled between the second port and the third port;a third power FET coupled between the first port and the third port;a dual ideal diode-OR controller coupled between the second and third power FETs to selectively turn on and off the second and third power FETs;a switch coupled to a control input of the first power FET;a controller, coupled to the switch, that selectively turns on and off the switch;wherein the controller monitors the power received at the first port and, when the power at the first port crosses a first threshold level, turns on the switch so that power is transmitted by the first and second power transistors between the second port and the third port and when the power at the first port crosses a second threshold level, turns off the switch so that power is transmitted by the third power transistor between ...

MELDRUM'S ACID, BARBITURIC ACID AND PYRAZOLONE DERIVATIVES SUBSTITUTED WITH HYDROXYLAMINE AS HNO DONORS

The disclosed subject matter provides certain N-substituted hydroxylamine derivative compounds, pharmaceutical compositions and kits comprising such compounds, and methods of using such compounds or pharmaceutical compositions. In particular, the disclosed subject matter provides methods of using such compounds or pharmaceutical compositions for treating, preventing, or delaying the onset and/or development of a disease or condition. In some embodiments, the disease or condition is selected from cardiovascular diseases, ischemia, reperfusion injury, cancerous disease, pulmonary hypertension and conditions responsive to nitroxyl therapy. 2. The compound of claim 1 , wherein the compound is of formula (I).3. The compound of claim 1 , wherein the compound is of formula (II).4. The compound of any one of to claim 1 , wherein R is C-Calkyl claim 1 , wherein the alkyl is unsubstituted or substituted with one or more substituents.5. The compound of any one of to claim 1 , wherein R is C-Calkyl.6. The compound of any one of to claim 1 , wherein R is —C(═NOR)R.7. The compound of any one of to claim 1 , wherein R is —C(═NOR)R; and Rand Rare independently C-Calkyl.87. The compound of any one of claim 1 , and to claim 1 , wherein X and Z are each —O—.97. The compound of any one of claim 1 , and to claim 1 , wherein X and Z are each —NR—.107. The compound of any one of claim 1 , and to claim 1 , wherein X and Z are each —NR—; and Ris C-Calkyl.1110. The compound of any one of claim 1 , and to claim 1 , wherein Y is —CRR—.1210. The compound of any one of claim 1 , and to claim 1 , wherein Y is —C(═O)—.137. The compound of any one of and to claim 1 , wherein Ris —H.147. The compound of any one of and to claim 1 , wherein Ris C-Calkyl claim 1 , wherein the alkyl is unsubstituted or substituted with one or more substituents.157. The compound of any one of and to claim 1 , wherein Ris C-Calkyl.167. The compound of any one of and to claim 1 , wherein Ris C-Caryl or C-Cheteroaryl claim ...

Engineered proteins and methods of use

Provided herein are proteins that include at least one B cell domain and at least one T cell domain. Also provided are compositions that include one or more of the proteins and methods for using the proteins.

ENERGY EFFICIENT PROCESSING DEVICE

An electronic device includes a low-energy-consumption display configured to display first information and a transparent high-energy-consumption display positioned with an area overlapping the low-energy-consumption display in a manner such that the first information is visible to a user through the area when the transparent high-energy-consumption display is in a sleep mode. 1. An electronic device comprising:a low-energy-consumption display configured to display first information; anda transparent high-energy-consumption display positioned with an area overlapping the low-energy-consumption display such that the first information is viewable through the area when the transparent high-energy-consumption display is in a sleep mode.2. The electronic device of claim 1 , wherein the transparent high-energy-consumption display is a light-emitting display and the low-energy-consumption display is a non-light-emitting display.3. The electronic device of claim 1 , wherein the transparent high-energy-consumption display is an organic light emitting diode (OLED) display.4. The electronic device of claim 1 , wherein the low-energy-consumption display is an e-ink display.5. The electronic device of claim 1 , wherein the transparent high-energy-consumption display and the low-energy-consumption display are parallel to one another.6. The electronic device of further comprising:a device mode detector stored in memory and executable by a processor to detect a change in a physical configuration of the electronic device; anda high-energy display controller stored in memory and executable by a processor to selectively alter a power state of the high-energy-consumption display responsive to the detected change in the physical configuration.7. The electronic device of claim 6 , wherein the electronic device is a watch and the device mode detector is configured to detect a change between a secured position and an unsecured position of a wearable band.8. An electronic device comprising:a ...

LOCATION-BASED AUTHENTICATION

An electronic device includes a location detector configured to determine a current device location and a location-based access controller configured to determine whether the current device location satisfies at least one predefined secure location criteria and to selectively preserve or disable a current user authentication session based on the determination. 1. A device comprising:a location detector stored in memory and executable by a processor to identify a current device location;a location-based access controller stored in the memory and executable by the processor to determine whether the current device location satisfies at least one predefined secure location criteria and selectively preserve or disable a current user authentication session based on the determination.2. The device of claim 1 , wherein the location-based access controller selectively preserves the current user authentication session when the current device location corresponds to a secure location stored in the memory.3. The device of claim 1 , wherein the location-based access controller selectively disables the current user authentication session and prompts a user for an authentication credential when the current device location does not correspond to a secure location stored in the memory.4. The device of claim 1 , wherein the location-based access controller selectively preserves or disables the current user authentication session responsive to a detected change in location satisfying a predefined location change criteria.5. The device of claim 1 , wherein the location-based access controller selectively preserves or disables the current user authentication session responsive to a detected change in a physical configuration of the device.6. The device of claim 5 , wherein the device is a watch and the detected change in the physical configuration is a change between a secured position and an unsecured position of a wearable band that provides a first electrical input to a processor ...

POLYPEPTIDES AND IMMUNIZING COMPOSITIONS CONTAINING GRAM POSITIVE POLYPEPTIDES AND METHODS OF USE

The present invention provides isolated polypeptides isolatable from a spp. Also provided by the present invention are compositions that include one or more of the polypeptides, and methods for making and methods for using the polypeptides. 1. A composition comprising:{'i': Staphylococcus aureus', 'S. aureus, 'two isolated polypeptides having molecular weights of 88 kDa, 55 kDa, 38 kDa, 37 kDa, 36 kDa, 35 kDa, 33 kDa, or a combination thereof, wherein molecular weight is determined by electrophoresis on a sodium dodecyl sulfate-polyacrylamide gel, wherein the polypeptides are isolatable from a when incubated in media comprising an iron chelator and not isolatable when grown in the media without the iron chelator, and wherein the composition protects an animal against challenge with ATCC strain 19636.'}229-. (canceled)30. A method comprising:{'i': 'Staphylococcus aureus', 'administering an effective amount of a composition to a subject at risk of developing lesions caused by infection by , the composition comprisingat least five isolated polypeptides having molecular weights of 88 kDa, 55 kDa, 38 kDa, 37 kDa, 36 kDa, 35 kDa, or 33 kDa, wherein molecular weight is determined by electrophoresis on a sodium dodecyl sulfate-polyacrylamide gel;{'i': 'Staphylococcus aureus', 'wherein the isolated polypeptide having a molecular weight of 88 kDa comprises an amino acid sequence having at least 95% identity to the amino acid sequence of a reference polypeptide, wherein the reference polypeptide has a molecular weight of 88 kDa as determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis, comprises the amino acid sequences depicted in SEQ ID NO:1, SEQ ID NO:2, SEQ ID NO:3, SEQ ID NO:4, SEQ ID NO:5, SEQ ID NO:6, SEQ ID NO:7, SEQ ID NO:9, SEQ ID NO:10, SEQ ID NO:11, SEQ ID NO:12, SEQ ID NO:13, SEQ ID NO:14, SEQ ID NO:15, SEQ ID NO:16, SEQ ID NO:17, SEQ ID NO:19, SEQ ID NO:20, SEQ ID NO:21, SEQ ID NO:22, SEQ ID NO:24, SEQ ID NO:25, SEQ ID NO:26, SEQ ID NO:27, SEQ ID ...

MULTI-SPEED TRANSMISSION

A transmission is provided having an input member, an output member, at least four planetary gear sets, a plurality of coupling members and a plurality of torque transmitting devices. Each of the planetary gear sets includes first, second and third members. The torque transmitting devices include clutches and a brake actuatable in combinations of four to establish a plurality of forward gear ratios and at least one reverse gear ratio. 1. A transmission comprising:an input member;an output member;first, second, third, and fourth planetary gear sets each having first, second, and third members, and wherein one of the first, second, and third members of the first, second, third and fourth planetary gear sets is fixed to a stationary member;three interconnecting members continuously interconnecting one of the first, second, and third members of the first, second, third and fourth planetary gear sets with another of the first, second, and third members of the first, second, third and fourth planetary gear sets; andsix torque transmitting mechanisms, and wherein each of the six torque transmitting mechanisms are selectively engageable to interconnect at least one of the first, second, and third members of the first, second, third, and fourth planetary gear sets with another of the first, second, third members of the first, second, third, and fourth planetary gear sets, a common rotating member, or the stationary member, andwherein the six torque transmitting mechanisms are selectively engageable in combinations of at least four to establish a plurality of forward speed ratios and at least one reverse speed ratio between the input member and the output member.2. The transmission of wherein a first of the three interconnecting members continuously interconnects the first member of the first planetary gear set with the first member of the second planetary gear set and a second of the three interconnecting members continuously interconnects a third member of the second ...

AUTOMATICALLY-SHIFTABLE HYBRID TRANSAXLE

An automatically-shiftable transaxle includes an input member configured to receive an external power-source torque and rotate about a first axis. The transaxle also includes torque transmitting device(s) and a gear-train, each operatively connected to the input member for selecting transaxle speed ratios, and a first transfer gear operatively connected to the gear-train and rotatable about the first axis. The transaxle also includes an intermediate shaft rotatable about a second axis, and a second transfer gear rotatably fixed to the intermediate shaft and meshed with the first transfer gear. The transaxle additionally includes an electric motor arranged on a third axis for providing a torque input to the second transfer gear. Furthermore, the transaxle includes a differential assembly operatively connected to the intermediate shaft and rotatable about a fourth axis to thereby transmit a transaxle output torque to drive the load. All four transaxle rotational axes are arranged in parallel. 1. An automatically-shiftable transaxle for mounting to an external power-source and transmitting a power-source torque therefrom , the transaxle comprising:an input member configured to receive the power-source torque and rotate about a first axis;a gear-train and at least one torque transmitting device, each operatively connected to the input member and cooperatively configured to select transaxle speed ratios;a first transfer gear operatively connected to the gear-train and configured to rotate about the first axis;an intermediate shaft configured to rotate about a second axis that is parallel to the first axis;a second transfer gear rotatably fixed to the intermediate shaft and in mesh with the first transfer gear;an electric motor arranged on a third axis that is parallel to the second axis and configured to provide an electric motor torque input to the second transfer gear; anda differential assembly operatively connected to the intermediate shaft and configured to rotate ...

YERSINIA SPP. POLYPEPTIDES AND METHODS OF USE

The present invention provides isolated polypeptides isolatable from a spp. Also provided by the present invention are compositions that include one or more of the polypeptides, and methods for making and methods for using the polypeptides. 162-. (canceled)63. A composition comprising:{'i': Yersinia', 'Yersinia, 'a spp. microbe expressing polypeptides expressed by the spp. at a greater level when incubated in media comprising an iron chelator than when grown in the media without the iron chelator; and'}an adjuvant.64YersiniaY. pestis.. The composition of wherein the spp. comprises65Y. pestisY. pestis. The composition of wherein the comprises strain KIM6+.66. The composition of wherein the polypeptides comprise:a first polypeptide having a molecular weight of 94 kDa as determined by electrophoresis on a sodium dodecyl sulfate-polyacrylamide gel;a second polypeptide having a molecular weight of 88 kDa as determined by electrophoresis on a sodium dodecyl sulfate-polyacrylamide gel;a third polypeptide having a molecular weight of 77 kDa as determined by electrophoresis on a sodium dodecyl sulfate-polyacrylamide gel;a fourth polypeptide having a molecular weight of 73 kDa as determined by electrophoresis on a sodium dodecyl sulfate-polyacrylamide gel; anda fifth polypeptide having a molecular weight of 64 kDa as determined by electrophoresis on a sodium dodecyl sulfate-polyacrylamide gel.67. The composition of wherein:the 94 kDa polypeptide comprises the amino acid sequences of SEQ ID NO:227, SEQ ID NO:229, SEQ ID NO:228, SEQ ID NO:230, SEQ ID NO:231, SEQ ID NO:232, SEQ ID NO:233, SEQ ID NO:234, SEQ ID NO:235, SEQ ID NO:237, SEQ ID NO:238, SEQ ID NO:239, SEQ ID NO:241, and SEQ ID NO:242;the 88 kDa polypeptide comprises the amino acid sequences of SEQ ID NO:243, SEQ ID NO:244, SEQ ID NO:245, SEQ ID NO:246, SEQ ID NO:247, SEQ ID NO:248, SEQ ID NO:249, SEQ ID NO:251, SEQ ID NO:252, SEQ ID NO:253, SEQ ID NO:254, SEQ ID NO:255, SEQ ID NO:256, SEQ ID NO:257, SEQ ID NO:258, and ...

PROTEINS AND IMMUNIZING COMPOSITIONS CONTAINING PASTEURELLA PROTEINS AND METHODS OF USE

The present invention provides isolated proteins isolatable from a spp. such as . Also provided by the present invention are compositions that include one or more of the proteins, and methods for making and methods for using the proteins. 1. A composition comprising:an isolated protein having at least 80% similarity to amino acids 25-968 of SEQ ID NO:2, an isolated protein having at least 80% similarity to amino acids 27-790 of SEQ ID NO:4, an isolated protein having at least 80% similarity to amino acids 23-727 of SEQ ID NO:6, an isolated protein having at least 80% similarity to amino acids 25-964 of SEQ ID NO:8, an isolated protein having at least 80% similarity to amino acids 26-848 of SEQ ID NO:10, an isolated protein having at least 80% similarity to amino acids 27-784 of SEQ ID NO:12, an isolated protein having at least 80% similarity to amino acids 25-742 of SEQ ID NO:14, an isolated protein having at least 80% similarity to amino acids 26-805 of SEQ ID NO:44, or a combination thereof; andan adjuvant;{'i': 'Pasteurella multocida.', 'wherein the composition protects a chicken against challenge with'}2. The composition of comprising the isolated protein having at least 80% similarity to amino acids 25-968 of SEQ ID NO:2 claim 1 , the isolated protein having at least 80% similarity to amino acids 27-790 of SEQ ID NO:4 claim 1 , the isolated protein having at least 80% similarity to amino acids 23-727 of SEQ ID NO:6 claim 1 , the isolated protein having at least 80% similarity to amino acids 25-964 of SEQ ID NO:8 claim 1 , the isolated protein having at least 80% similarity to amino acids 26-848 of SEQ ID NO:10 claim 1 , the isolated protein having at least 80% similarity to amino acids 27-784 of SEQ ID NO:12 claim 1 , and the isolated protein having at least 80% similarity to amino acids 25-742 of SEQ ID NO:14.3. A composition comprising:{'i': 'Pasteurella multocida', 'isolated proteins having molecular weights of 99 kDa, 81 kDa, and 80 kDa, wherein the ...

Process for the preparation of 7-(4,7-diazaspiro[2.5]octan-7-yl)-2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)pyrido[1,2-a]pyrimidin-4-one derivatives

The present invention relates to a process for the preparation of 7-(4,7-diazaspiro[2.5]octan-7-yl)-2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)pyrido[1,2-a]pyrimidin-4-one derivatives useful as pharmaceutically active compounds.

POLYPEPTIDES OF FUSOBACTERIUM AND METHODS OF USE

The present invention provides isolated polypeptides isolatable from a spp. Also provided by the present invention are compositions that include one or more of the polypeptides, and methods for making and methods for using the polypeptides. 1. A composition comprising:{'i': 'Fusobacterium necrophorum', 'at least one isolated polypeptide having a molecular weight of 92 kDa to 79 kDa, 73 kDa to 63 kDa, 62 kDa to 58 kDa, or 57 kDa to 47 kDa, wherein the at least one polypeptide is isolatable from a when incubated in media comprising an iron chelator and not isolatable when grown in the media without the iron chelator,'}{'i': Fusobacterium necrophorum', 'Fusobacterium necrophorum, 'at least one isolated polypeptide having a molecular weight of 108 kDa to 98 kDa or 79 kDa to 69 kDa, wherein the at least one polypeptide is isolatable from a when incubated in media comprising an iron chelator, is expressed by the when incubated in media without the iron chelator and expressed at an enhanced level during growth in media comprising an iron chelator, and'}at least one protein selected from the group consisting of a polypeptide having at least 85% similarity to SEQ ID NO:4 or a fragment thereof, a polypeptide having at least 85% similarity to SEQ ID NO:2 or a fragment thereof, a polypeptide having at least 85% similarity to SEQ ID NO:6 or a fragment thereof, a polypeptide having at least 85% similarity to SEQ ID NO:34 or a fragment thereof, and a polypeptide having at least 85% similarity to SEQ ID NO:53 or a fragment thereof,{'i': 'Fusobacterium necrophorum.', 'wherein the composition protects an animal against challenge with'}2. (canceled)3. A composition comprising:{'i': 'Fusobacterium necrophorum', 'isolated polypeptides having molecular weights of 92 kDa to 79 kDa, 73 kDa to 63 kDa, 62 kDa to 58 kDa, and 57 kDa to 47 kDa, wherein the polypeptides are isolatable from a when incubated in media comprising an iron chelator and not isolatable when grown in the media without ...

Portable silo assembly

A portable silo assembly includes two or more telescopic silos. Each of the telescopic silos are multi-stage structures that are vertically movable from a collapsed transport position to a telescopically expanded operative position. A rigid underlying base structure is provided upon which the two or more telescopic silos are mounted. A jacking assembly is provided for jacking the two or more telescopic silos from the collapsed transport position to the expanded operative position. A rigidifying truss system provided rigidity between the two or more telescopic silos during transport and as the two or more telescopic silos are jacked from the collapsed transport position to the expanded operative position.

Systems and methods for monitoring a subject under the influence of drugs

Systems and methods for monitoring a subject under, or suspected to be under, the influence of one or more drugs are provided. In one aspect, a method comprises controlling one or more sensors of a monitoring device to acquire physiological signals from a subject suspected to be under the influence of one or more drugs, and assembling a set of physiological data using the acquired physiological signals. The method also includes generating, using a processor of the monitoring device, physiological markers characteristic of the influence of the one or more drugs by analyzing the set of physiological data, and correlating the physiological markers with a drug profile characterizing the one or more drugs affecting the subject. The method further includes proving to a user a report indicating the drug profile characterizing the one or more drugs affecting the subject.

Methods for Removal of Moisture from LNG Refrigerant

Methods and systems for removing moisture from refrigerant that use a desiccant-based moisture removal unit can be used in the production of liquid natural gas (LNG). For example, a method can include: compressing a refrigerant; conveying at least a portion of the refrigerant to a moisture removal unit comprising a desiccant to form dehydrated refrigerant; cooling and condensing the dehydrated refrigerant to provide a cooled dehydrated liquid refrigerant; conveying the cooled dehydrated refrigerant to a heat exchanger; and passing a LNG stream rich in methane through the heat exchanger to cool at least part of the LNG stream by indirect heat exchange with the cooled dehydrated refrigerant.