Imageable lipid-oil-water nanoemulsion delivery system

A stable lipid-oil-water nanoemulsion associated with an imaging agent is useful for imaging cells characterized by aberrant lipid metabolism and/or cellular hyperproliferation, such as cancer cells, in an exquisitely specific and selective manner compared to non-transformed cells.

Imageable lipid-oil-water nanoemulsion diagnostic delivery system

A stable lipid-oil-water nanoemulsion associated with an imaging agent and a diagnostic agent is useful both for imaging cells characterized by aberrant lipid metabolism and/or cellular hyperproliferation, such as cancer cells, and for diagnosing the cancer in an exquisitely specific and selective manner compared to non-transformed cells.

Imageable lipid-oil-water nanoemulsion therapeutic delivery system

A stable lipid-oil-water nanoemulsion associated with an imaging agent and a therapeutic agent is useful for both imaging and treating cells characterized by aberrant lipid metabolism and/or cellular hyperproliferation, such as cancer cells, in an exquisitely specific and selective manner compared to non-transformed cells.

Decorative wallcovering in roll form

A decorative wallcovering in roll form of the kind that is applied to the wall with adhesive, has a strength giving substrate ply (10), a mechanically foamed ply (11) having open and closed pores (13) with a decorative effect (12) on its exposed surface. A diffusion porous toughened surface (14) and print hold-out coat (15) is preferably provided before a printed decorative effect is applied. The print (12) may be hostile to the foam so long as the print application and drying is performed quickly. Texture effect can be achieved by selecting a substrate which has a degree of preferential absorption of one of the constituents of the foam in selected regions.

Automotive body shroud and rocker panel construction

Timing control system

Highly reactive, water soluble carbodiimides, intermediates and derivatives thereof

Novel water soluble carbodiimides, and intermediates or derivatives thereof, such as isoureas or isothioureas, are described. A particularly preferred embodiment is bis[4-(2,2-dimethyl-1,3-dioxolyl)methyl] carbodiimide (BDDC), which can be synthesized efficiently from 1,2-isopropylideneglycerol (solketal). The isoureas are effective esterifying agents. The corresponding N-protected amino acid tert-butyl, benzyl, isopropyl, ethyl, and methyl esters can be synthesized in high yield under neutral conditions, with no urea residue after simply washing with aqueous acid. Amino acid couplings utilizing carbodiimide embodiments give peptides in good yield, free of carbodiimide by-products, after washing with dilute acid, while racemization-free peptides are also obtained.

Apparatus incorporating phase conjugate mirrors

Image projecting apparatus comprising a source of radiation to illuminate an object (O), a partially reflecting beam splitter to reflect radiation from the object on to a phase conjugate mirror (PCM), a phase conjugate mirror to reflect said radiation through said beam splitter to construct a real image (I) of said object and a compensator (C) interposed between said object and said beam splitter means to compensate at least partially for abberations in said image caused by the beam splitter.

Magneto

Improved cryo-slammer

Process for preparing 4-alkyl-or 4-aryl-oxycarbonyl paclitaxel analogs and novel intermediates

Immunization with porphyromonas gingivalis protects against heart disease

Glass-molding machine.

Vulcanizer.

Improvements relating to automobile bodies

Process for preparing 4-alkyl- or 4-aryl-oxycarbonyl paclitaxel analogs and novel intermediates

A process is provided for preparing 4-alkyl- or 4-aryl-oxycarbonyl paclitaxel analogs which includes the steps of converting paclitaxel into a C-7 acylprotected paclitaxel employing an electrophilic protecting group, such as benzoyloxycarbonyl, and converting the C-7 protected analog into the 4-alkyloxycarbonyl or 4-aryloxycarbonyl paclitaxel analog. Novel intermediates produced in the process are also provided.

Vehicle sealing means

Toy bowling-alley.

Glass-molding machine.

Jar and closure therefor.

Improvements relating to automobile bodies

Perfectionnements aux pyromètres

High-pressure gate for photographic contact printing

A new photographic printing apparatus with which contact prints are made by exposing the original film and the printing stock material at a time when they are brought into intimate contact with one another by pneumatic pressure. The sandwich arrangement of film and printing stock is passed over a drum above which is contiguously disposed a ''''shoe'''' mechanism that is contoured to be partially concentric with the drum, a small or narrow air gap separating the drum and shoe whereat they are concentric. The air, under pressure, is applied to the film from the shoe side and escapes through the air gap, the entire arrangement providing the pressure distribution needed to achieve fine contact printing.

Fire alarm box

Voice frequency ringing receiver

Refrigerator construction

Voice frequency ringing receiver

Cephalosporin compositions

Fan and spray wheel attachment for hose nozzles

Cephalosporin compositions