6-CYCLYLMETHYL-AND 6-ALKYLMETHYL-SUBSTITUTED PYRAZOLEPYRIMIDINES

The invention relates to novel 6-cyclylmethyl- and 6-alkylmethyl-substituted pyrazolopyrimidines, process for their preparation and their use for producing medicaments for improving perception, concentration, learning and/or memory. 2. A compound according to claim 1 , where{'sup': '1', 'sub': 1', '8', '2', '6', '2', '6', '3', '8', '1', '6', '1', '6', '1', '6', '6', '10', '1', '6', '1', '6', '6', '10', '1', '6', '1', '6', '1', '6, 'claim-text': [{'sub': 1', '6', '1', '6', '1', '6', '6', '10', '1', '6', '1', '6', '1', '6, 'where C-C-alkyl, C-C-alkoxy, C-C-alkylamino, C-C-arylcarbonylamino, C-C-alkylcarbonylamino, C-C-alkylaminocarbonyl, C-Calkoxy carbonyl,'}, {'sub': 6', '10, 'C-C-arylaminocarbonyl, heteroarylaminocarbonyl, heteroarylcarbonylamino,'}, {'sub': 1', '6', '1', '6', '1', '6, 'sup': 3', '4, 'C-C-alkylsulphonylamino, C-C-alkylsulphonyl and C-C-alkylthio are optionally substituted by a radical selected from the group of hydroxy, cyano, halogen, hydroxycarbonyl and a group of the formula —NRR,'}, 'where', {'sup': 3', '4, 'sub': 1', '6, 'Rand Rare independently of one another hydrogen or C-C-alkyl,'}, 'or', {'sup': 3', '4, 'Rand Rtogether with the nitrogen atom to which they are bonded are 5- to 8-membered heterocyclyl,'}], 'Ris C-C-alkyl, C-C-alkenyl, C-C-alkynyl or C-C-cycloalkyl, which are optionally substituted by up to 3 radicals independently of one another selected from the group of C-C-alkyl, C-C-alkoxy, hydroxycarbonyl, cyano, amino, nitro, hydroxy, C-C-alkylamino, halogen, C-C-arylcarbonylamino, alkylcarbonylamino, C-C-alkylaminocarbonyl, C-C-alkoxycarbonyl, C-C-arylaminocarbonyl, heteroarylaminocarbonyl, heteroarylcarbonylamino, C-C-alkylsulphonylamino, C-C-alkylsulphonyl and C-C-alkylthio,'}{'sup': '2', 'sub': 1', '6', '1', '6', '1', '6', '6', '10', '1', '6', '1', '6', '1', '6', '6', '10', '1', '6', '1', '6', '1', '6, 'claim-text': {'sub': 1', '6', '1', '6', '1', '6', '6', '10', '1', '6', '1', '6', '1', '6', '6', '10', '1', '6', '1', '6', '1', '6, ...

N-BIARYLAMIDES

The invention relates to N-biarylamides useful for the prophylaxis and/or treatment of impairments of perception, concentration, learning and/or memory, and to processes for preparing them, and pharmaceutical compositions containing them. 2. The method of claim 1 , wherein the cognitive impairment is age-associated learning or memory impairment claim 1 , age-associated memory loss claim 1 , vascular dementia claim 1 , craniocerebral trauma claim 1 , stroke claim 1 , post-stroke dementia claim 1 , post-traumatic craniocerebral trauma claim 1 , general concentration impairment claim 1 , concentration impairment in children with learning and memory problems claim 1 , attention deficity hyperactivity disorder claim 1 , Alzheimer's disease claim 1 , Lewy body dementia claim 1 , dementia with degeneration of the frontal lobes claim 1 , Pick's syndrome claim 1 , Parkinson's disease claim 1 , progressive nuclear palsy claim 1 , dementia with corticobasal degeneration claim 1 , amyotrophic lateral sclerosis (ALS) claim 1 , Huntington's disease claim 1 , multiple sclerosis claim 1 , thalamic degeneration claim 1 , Creutzfeld-Jacob dementia claim 1 , HIV dementia claim 1 , schizophrenia claim 1 , of schizophrenia with dementia or Korsakoff's psychosis.3. The method of claim 2 , wherein the cognitive impairment is Alzheimer's disease.4. The method of wherein the wherein the cognitive impairment is schizophrenia.5. The method of claim 1 , further comprising co-administering a second active ingredient for the treatment of the cognitive impairment.6. The method of claim 1 , wherein the administering is by an oral claim 1 , transdermal claim 1 , parenteral or inhalation route. The invention relates to N-biarylamides, to a process for the preparation thereof and to the use thereof for producing medicaments for the treatment and/or prophylaxis of diseases and for improving perception, concentration, learning and/or memory.Nicotinic acetylcholine receptors (nAChR) form a large family ...

2-HETEROARYL CARBOXAMIDES

The invention relates to novel 2-heteroaryl carboxamides and to the use thereof for producing medicaments for the treatment and/or prophylaxis of diseases and for improving perception, concentration, learning and/or memory. 2. Compounds according to claim 1 , of the formula (I) claim 1 , in which{'sup': '1', 'Ris 1-azabicyclo[2.2.2]oct-3-yl,'}{'sup': '2', 'sub': 1', '4, 'Ris hydrogen or C-C-alkyl,'}{'sup': '3', 'sub': 1', '4, 'Ris hydrogen, fluorine, chlorine, bromine or C-C-alkyl,'}{'sup': '4', 'sub': 1', '4', '1', '4', '1', '4', '1', '4', '1', '4', '1', '4', '1', '4', '1', '4', '3', '6', '3', '6', '1', '4, 'claim-text': {'sub': 1', '4', '1', '4', '1', '4, 'claim-text': [{'sub': 1', '4', '1', '4', '1', '4, 'C-C-alkylaminocarbonyl may optionally be substituted by C-C-alkoxy or C-C-alkylamino,'}, {'sub': 1', '4', '1', '4, 'C-C-alkylcarbonylamino may optionally be substituted by C-C-alkoxy, and, heterocyclyl may optionally be substituted by oxo,'}], 'where C-C-alkyl may optionally be substituted by hydroxyl, cyano, amino, C-C-alkylaminocarbonylamino, C-C-alkylaminocarboxyl, heterocyclyl or aryl,'}, 'Ris hydrogen, fluorine, chlorine, bromine, cyano, amino, trifluoromethyl, trifluoromethoxy, C-C-alkyl, C-C-alkylcarbonyl, C-C-alkylamino, formyl, hydroxycarbonyl, C-C-alkoxy, C-C-alkoxycarbonyl, C-C-alkylcarbonylamino, C-C-alkylaminocarbonyl, C-C-alkylsulphonylamino, C-C-cycloalkyl-carbonylamino, C-C-cycloalkylaminocarbonyl, pyrrolyl, C-C-alkylaminocarbonylamino, heterocyclylcarbonyl, heterocyclylcarbonylamino, heteroarylcarbonylamino, hydroxyl, phenyl or heterocyclyl,'}A is oxygen or sulphur;{'sub': 1', '4, 'the ring B is benzo or pyrido, each of which are optionally substituted by radicals from the series halogen, cyano, trifluoromethyl, trifluoromethoxy and C-C-alkyl,'}and{'sub': 1', '4', '1', '4, 'E is C≡C, arylene and heteroarylene, where arylene and heteroarylene may be substituted by radicals from the series halogen, cyano, trifluoromethyl, trifluoromethoxy, nitro, ...

AZABICYCLIC CARBAMATES AND THEIR USE AS ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTOR AGONISTS

The invention relates to novel benzothiophene-, benzofuran-, and indole ureas and to the use thereof for producing medicaments for the treatment and/or prophylaxis of diseases and for improving perception, concentration, learning, and/or memory. 115-. (canceled)17. The pharmaceutical composition of claim 16 , wherein:{'sup': 6', '5', '6, 'sub': 1', '6', '1', '8', '6', '10', '1', '6', '1', '6', '1', '6', '6', '10', '1', '6', '1', '6', '1', '6', '1', '6', '1', '6', '1', '6, 'Rrepresents (i) hydrogen, (ii) C-C-alkyl, (iii) C-C-cycloalkyl, (iv) C-C-aryl, or (v) 5- to 10-membered heteroaryl, where (ii) is optionally substituted by phenyl, or C-C-alkoxy, and (iv) and (v) are optionally substituted by up to 3 radicals selected independently of one another from the group of C-C-alkyl, C-C-hydroxyalkyl, 3- to 8-membered heterocyclyl, C-C-aryl, 5- to 10-membered heteroaryl, hydroxy, halogen, cyano, C-C-alkoxy, C-C-acyl, trifluoromethyl, trifluoromethoxy, nitro, amino, C-C-alkylamino, or C-C-acylamino; or Rand Rtogether with the nitrogen atom to which they are bonded are a 3- to 8-membered heterocycle which is optionally substituted by C-C-alkyl or C-C-hydroxyalkyl; and'}A represents oxygen.18. The pharmaceutical composition of claim 16 , wherein:{'sup': '2', 'sub': 1', '4, 'Rrepresents hydrogen or C-C-alkyl;'}{'sup': '3', 'sub': 1', '4, 'Rrepresents hydrogen, halogen, amino, hydroxy or C-C-alkyl;'}{'sup': '4', 'sub': 1', '4', '1', '3, 'Rrepresents hydrogen or C-C-alkyl which is optionally substituted by a radical selected from the group of hydroxy, halogen, cyano, C-C-alkoxy, trifluoromethyl or trifluoromethoxy;'}{'sup': 5', '4', '5, 'sub': 1', '4', '1', '6', '1', '4, 'Rrepresents hydrogen or C-C-alkyl, or Rand Rrepresents together with the nitrogen atom to which they are bonded are a 5- to 6-membered heterocycle which is optionally substituted by up to 2 substituents independently of one another selected from the group of C-C-alkyl, C-C-acyl, oxo, thioxo;'}{'sup': 6', '5', ' ...

ELECTROSURGICAL INSTRUMENT

A surgical instrument includes an elongated shaft, with components arranged in the shaft. The elongated shaft is slightly curved. Arranged on a proximal end of the surgical instrument is an actuation device in the form of a lever mechanism and rotary knob. A force transmission element in the form of a plastic hollow section is arranged in the shaft. The force transmission element is a plastic section designed for transmitting compressive and tensile forces. The plastic section is provided with a plurality of longitudinally extending channels. Therefore, the plastic section does not only serve as a force transmission element, but electric lines and a pull-push shaft may additionally extend in the channels. The longitudinal channels may be used for supplying cooling media for the electrodes or the thermo-fusion device or for feeding agents promoting wound repair. The plastic section is electrically insulating, so that the risk of short-circuits is reduced. 1. A surgical instrument , in particular an electrosurgical instrument , comprisingan instrument shaft comprising a proximal end and a distal end,a tool unit arranged on the distal end of the instrument shaft,an actuation device for actuating the tool unit and arranged on the proximal end of the instrument shaft,a force transmission element which is arranged in the interior of the instrument shaft and provided for a force-fitting connection between the actuation device and the tool unit,the force transmission element being a bendable and flexible plastic section designed for transmitting tensile and compressive forces, andin that the plastic section comprises a number of channels extending in longitudinal direction and preferably along the entire length of the section.2. An electrosurgical instrument in the form of a circular sealing instrument in RF design , comprisingan instrument shaft comprising a proximal end and a distal end,a tool unit arranged on the distal end of the instrument shaft, said tool unit ...

Stamping press arrangement

The invention relates to a stamping press arrangement comprising a plurality of first stamping press units arranged adjacent to one another, which have working directions extending parallel in relation to each other in a common plane, and comprising a second stamping press unit, the working direction of which extends perpendicularly in relation to the working directions of the first stamping press units, such that material processed in said stamping press unit can be guided in the direct extension of the working direction thereof into the working regions of the first stamping press units. The stamping press units each have a crankshaft portion or eccentric shaft portion, by means of which the travel movement of the press ram is effected via a connecting rod. The crankshaft portion or eccentric shaft portion of the first stamping press units are driven forcibly together via a common drive unit with the same speed and comprise a common axis of rotation. The crankshaft portion or eccentric shaft portion of the stamping press unit is coupled to the crankshaft portion or eccentric shaft portion of the first stamping press units so as to forcibly rotate therewith in a synchronous manner. The invention allows high-precision and high-speed stamping press arrangements to be provided for economically mass-producing multi-part stamping and shaped and punched products which have low tolerances, such as container ends with press-in or pull tabs for opening without tools, in a cost-effective manner.

AZABICYCLIC CARBAMATES AND THEIR USE AS ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTOR AGONISTS

The invention relates to novel benzothiophene-, benzofuran-, and indole ureas and to the use thereof for producing medicaments for the treatment and/or prophylaxis of diseases and for improving perception, concentration, learning, and/or memory. 12. A medicament comprising at least one compound as claimed in and at least one pharmaceutically acceptable claim 1 , essentially nontoxic carrier or excipient.13. A method for improving perception claim 1 , concentration claim 1 , learning and/or memory comprising administering to a human or animal an effective amount of a compound of .14. A method for the treatment and/or prophylaxis of impairments of perception claim 1 , concentration claim 1 , learning and/or memory comprising administering to a human or animal an effective amount of a compound of .15. A method for the treatment and/or prophylaxis of impairments of perception claim 12 , concentration claim 12 , learning and/or memory comprising administering to a human or animal an effective amount of a medicament of . The invention relates to novel benzothiophene-, benzofuran- and indoleureas, processes for their preparation, and their use for producing medicaments for the treatment and/or prophylaxis of diseases and for improving perception, concentration, learning and/or memory.Nicotinic acetylcholine receptors (nAChR) form a large family of ion channels which are activated by the messenger acetylcholine which is produced in the body (Galzi et al., 1995, 34, 563-582). A functional nAChR consists of five subunits which may be different (certain combinations of α1-9 and (β1-4,γ,δ,ε subUnits) or identical (α 7-9). This leads˜to the formation of a diversity of subtypes which differ in the distribution in the muscles, the nervous system and other organs (McGehee et al, 1995, 57, 521-546). Activation of nAChR leads to influx of cations into the cell and to stimulation of nerve cells or muscle cells. Selective activation of individual nAChR subtypes restricts this ...

Vehicle parking assist system

A method for assisting in parking a vehicle, comprises the steps of: initiating a parking sequence having a reference velocity; altering a velocity of the vehicle to about the reference velocity by generating a brake torque during a first mode of operation of a controller; outputting the brake torque to a disturbance estimator; storing the brake torque within the disturbance estimator; and utilizing the brake torque from the disturbance estimator in a second mode of operation of the controller to stop the vehicle at a target location.

Waste receptacle dollies and anchors

Dollies and anchors for securing the movement of waste receptacles are provided. A dolly includes a dolly base configured to securely receive an enclosed base portion of a waste receptacle. The waste receptacle has at least one sidewall extending from the enclosed base portion to define an open top portion. The open top portion is defined by a rim and configured to receive waste material therethrough. The dolly base is coupled with at least two wheels and at least one elongated shaft. At least one elongated shaft extends in a direction substantially traverse to the dolly base.

Inertial reference for tba speed limiting

A method of controlling a vehicle while the vehicle is backing up with a trailer attached thereto. The vehicle may include a brake system and a power train system. The method includes determining a trailer yaw rate, and estimating a modified trailer curvature. The modified trailer curvature comprises a ratio of the trailer yaw rate to the vehicle speed. The method further includes determining a maximum allowable vehicle speed as a function of modified trailer curvature utilizing predefined criteria that defines a maximum allowable vehicle speed for a given modified trailer curvature. The method further includes limiting the vehicle speed such that the maximum allowable vehicle speed is not exceeded.

2-HETEROARYL CARBOXAMIDES

The invention relates to novel 2-heteroaryl carboxamides and to the use thereof for producing medicaments for the treatment and/or prophylaxis of diseases and for improving perception, concentration, learning and/or memory. 2. Compounds according to claim 1 , of the formula (I) claim 1 , in which{'sup': '1', 'Ris 1-azabicyclo[2.2.2]oct-3-yl,'}{'sup': '2', 'sub': 1', '4, 'Ris hydrogen or C-C-alkyl,'}{'sup': '3', 'sub': 1', '4, 'Ris hydrogen, fluorine, chlorine, bromine or C-C-alkyl,'}{'sup': '4', 'sub': 1', '4', '1', '4', '1', '4', '1', '4', '1', '4', '1', '4', '1', '4', '1', '4', '1', '4', '3', '6', '3', '6', '1', '4, 'claim-text': {'sub': 1', '4', '1', '4', '1', '4, 'claim-text': [{'sub': 1', '4', '1', '4', '1', '4, 'C-C-alkylaminocarbonyl may optionally be substituted by C-C-alkoxy or C-C-alkylamino,'}, {'sub': 1', '4', '1', '4, 'C-C-alkylcarbonylamino may optionally be substituted by C-C-alkoxy, and, heterocyclyl may optionally be substituted by oxo,'}], 'where C-C-alkyl may optionally be substituted by hydroxyl, cyano, amino, C-C-alkylaminocarbonylamino, C-C-alkylaminocarboxyl, heterocyclyl or aryl,'}, 'Ris hydrogen, fluorine, chlorine, bromine, cyano, amino, trifluoromethyl, trifluoromethoxy, C-C-alkyl, C-C-alkylcarbonyl, C-C-alkylamino, formyl, hydroxycarbonyl, C-C-alkoxy, C-C-alkoxycarbonyl, C-C-alkylthio, C-C-alkylcarbonylamino, C-C-alkylaminocarbonyl, C-C-alkylsulphonylamino, C-C-cycloalkylcarbonylamino, C-C-cycloalkylaminocarbonyl, pyrrolyl, C-C-alkylaminocarbonylamino, heterocyclylcarbonyl, heterocyclylcarbonylamino, heteroarylcarbonylamino, hydroxyl, phenyl or heterocyclyl,'}A is oxygen or sulphur;{'sub': 1', '4, 'the ring B is benzo or pyrido, each of which are optionally substituted by radicals from the series halogen, cyano, trifluoromethyl, trifluoromethoxy and C-C-alkyl,'}and{'sub': 1', '4', '1', '4, 'E is C≡C, arylene and heteroarylene, where arylene and heteroarylene may be substituted by radicals from the series halogen, cyano, trifluoromethyl, ...

AZABICYCLIC CARBAMATES AND THEIR USE AS ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTOR AGONISTS

The invention relates to novel benzothiophene-, benzofuran-, and indole ureas and to the use thereof for producing medicaments for the treatment and/or prophylaxis of diseases and for improving perception, concentration, learning, and/or memory. 115-. (canceled) The invention relates to novel benzothiophene-, benzofuran- and indoleureas, processes for their preparation, and their use for producing medicaments for the treatment and/or prophylaxis of diseases and for improving perception, concentration, learning and/or memory.Nicotinic acetylcholine receptors (nAChR) form a large family of ion channels which are activated by the messenger acetylcholine which is produced in the body (Galzi et al., 1995, 34, 563-582). A functional nAChR consists of five subunits which may be different (certain combinations of α1-9 and (β1-4,γ,δ,ε subunits) or identical (α 7-9). This leads˜to the formation of a diversity of subtypes which differ in the distribution in the muscles, the nervous system and other organs (McGehee et al., 1925, 57, 521-546). Activation of nAChR leads to influx of cations into the cell and to stimulation of nerve cells or muscle cells. Selective activation of individual nAChR subtypes restricts this stimulation to the cell types which have a corresponding subtype and is thus able to avoid unwanted side effects such as, for example, stimulation of nAChR in the muscles. Clinical experiments with nicotine and experiments in various animal models indicate that central nicotinic acetylcholine receptors are involved in learning and memory processes (e.g. Rezvani et al., 2001, 49, 258-267).Nicotinic acetylcholine receptors of the alpha7 subtype (α7 nAChR) have a particularly high concentration in regions of the brain which are important for learning and memory, such as the hippocampus and the cerebral cortex (Séguéla et al., 1993, 13, 596-604). The α7 nAChR has a particularly high permeability for calcium ions, increases glutamatergic neuotransmission influences the ...

Method for bending the machine bed of a stamping press, and stamping press

A method for warping the machine bed of a punching press, which machine bed has an aperture for carrying away punching parts and rubbish, compensates at least partially for a bending of the machine bed caused by the punching force during the punching operation. Thereby, forces acting transverse to the punching direction are introduced into the machine bed and/or forces acting transverse to the punching force direction are produced inside the machine bed, by means of which the machine bed warps in the direction towards the press ram and indeed such that it warps stronger in the area adjacent to the aperture than in the areas adjacent to its longitudinal sides. By the method, apertured machine beds of punching presses can, with very little expenses on the equipment side, be spatially pre-deformed in order to compensate at least partially bendings caused by punching forces.

Method for warping the machine bed and/or the press ram of a punching press and punching press

The invention relates a method for warping the machine bed and/or the press ram of a punching press to compensate at least partially a bending caused by the punching force of the machine bed or the press ram during punching operation, respectively. For this a temperature gradient is generated selectively within the machine bed and/or within the press ram according to the invention, with the effect of making the machine bed warping in the direction towards the press ram and/or the press ram warping in the direction towards the press bed. In this way, machine beds and press rams of punching presses can be pre-deformed for the compensation of bendings caused by the punching force with a very small expenses on the equipment side, without having to deviate from existing and proven structure concepts. Additionally the method according to the invention can be applied to existing presses.

Surgical Tissue Fusion Instrument

Surgical tissue fusion instrument having two gripping structures which are movable relative to each other, are designed for gripping and bringing together biological tissue sections, and are assigned heat-generating means designed in such a way that tissue fusion takes place between the biological tissue sections by heat being supplied in the area of the gripping structures. At least one gripping structure is assigned a fluid-conducting system, which is designed to supply at least one liquid or flowable additive to the tissue sections during a tissue fusion process. 115-. (canceled)16. A surgical tissue fusion instrument with two gripping structures which are movable relative to each other , are designed for gripping and bringing together biological tissue sections , and are assigned heat-generating means designed in such a way that tissue fusion takes place between the biological tissue sections by heat being supplied in the area of the gripping structures , characterized in that at least one gripping structure is assigned a fluid-conducting system , which is designed to supply at least one liquid or flowable additive to the tissue sections during a tissue fusion procedure.17. The surgical tissue fusion instrument of claim 16 , characterized in that the fluid-conducting system has at least one fluid-conducting channel claim 16 , which is integrated in one of the two gripping structures.18. The surgical tissue fusion instrument of claim 17 , characterized in that the fluid-conducting system has at least one fluid reservoir claim 17 , which is connected to the fluid-conducting channel.19. The surgical tissue fusion instrument of claim 17 , characterized in that at least one gripping structure is provided with fluid outlet openings claim 17 , into which the at least one fluid-conducting channel opens.20. The surgical tissue fusion instrument of claim 18 , characterized in that the at least one fluid reservoir is integrated in at least one gripping structure.21. The ...

N-BIARYLAMIDES

The invention relates to N-biarylamides, methods for production and use thereof for the production of medicaments for the treatment and/or prophylaxis of diseases and for improvement in cognition, concentration power, learning power and/or memory. 2. The compound as claimed in claim 1 , where{'sup': 1', '2', '3', '4', '2', '5', '6', '7', '8, 'sub': 2', '2, 'claim-text': [{'sup': '2', 'sub': 1', '4, 'Ris hydrogen or C-C-alkyl,'}, {'sup': 3', '4, 'sub': 1', '4', '3', '6', '1', '4', '1', '4, 'Rand Rare independently of one another hydrogen, C-C-alkyl, C-C-cycloalkyl or phenyl, which is optionally substituted by up to 2 radicals independently of one another selected from the group of fluorine, chlorine, bromine, cyano, C-C-alkyl, C-C-alkoxy, trifluoromethyl and trifluoromethoxy, or'}, {'sup': 3', '4, 'Rand Rtogether with the nitrogen atom to which they are bonded form a 5- to 6-membered heterocyclyl,'}, {'sup': '5', 'sub': 1', '4', '3', '6', '1', '4, 'Ris hydrogen, C-C-alkyl, C-C-cycloalkyl, or aryl, where C-C-alkyl is optionally substituted by aryl,'}, {'sup': '6', 'sub': 1', '4', '3', '6', '1', '4, 'Ris C-C-alkyl, C-C-cycloalkyl, 5- to 6-membered heterocyclyl, aryl or 5- to 6-membered heteroaryl, where C-C-alkyl is optionally substituted by aryl,'}, {'sup': '7', 'sub': 1', '4', '3', '6', '1', '4, 'Ris hydrogen, C-C-alkyl, C-C-cycloalkyl, 5- to 6-membered heterocyclyl, aryl or 5- to 6-membered heteroaryl, where C-C-alkyl is optionally substituted by aryl,'}, {'sup': '8', 'sub': 3', '6', '1', '4', '1', '4', '1', '4', '1', '4', '1', '4, 'Ris C-C-cycloalkyl, C-C-alkyl or phenyl, where C-C-alkyl is substituted by C-C-alkoxy and phenyl by 1 to 2 radicals independently of one another selected from the group of fluorine, chlorine, bromine, cyano, C-C-alkyl, C-C-alkoxy, trifluoromethyl and trifluoromethoxy,'}], 'Ris a group of the formula —NR—CO—NRR, —NR—CO—CO—OR, —NH—SOR, —SONHRor —NH—CO—R, where'}and the salts, solvates and solvates of the salts thereof.3. The compound as ...

Trailer backup assist system with trajectory planner for multiple waypoints

A trailer backup assist system, according to one embodiment, includes a state estimator that determines a current position of a trailer relative to a plurality of waypoints. A trajectory planner may then incrementally generate a path from the current position to the plurality of waypoints. The trajectory planner has a first mode that generates first and second circular trajectories tangent to one another connecting between the current position and a waypoint of the plurality of waypoints. A second mode of the trajectory planner generates the second circular trajectory between the current position and the waypoint after the trailer traverses the first circular trajectory. Also, a third mode of the trajectory planner switches to the first operating mode when the trailer reaches the waypoint for guidance to a subsequent waypoint. A curvature controller guides the trailer based on a curvature of the respective first or second circular trajectories.

Surgical Tissue Fusion Instrument and Support Structure for Same

Surgical tissue fusion instrument and support structure having two gripping structures which are movable relative to each other and which are designed to bring together biological tissue sections that are to be connected to each other, with heat-generating means which are assigned to the gripping structures and, during tissue fusion, cause heat to be introduced in the area of a connection site of the biological tissue sections, and also with a support structure which is held between the gripping structures and, during tissue fusion, is operatively connected to the tissue sections. The support structure has at least one additional physical functional structure for aiding or promoting the tissue fusion. 114-. (canceled)15. A surgical tissue fusion instrument with two gripping structures which are movable relative to each other and which are designed to bring together biological tissue sections (G , G) that are to be connected to each other , with heat-generating means which are assigned to the gripping structures and , during tissue fusion , cause heat to be introduced in the area of a connection site of the biological tissue sections (G , G) , and also with a support structure which is assigned to the gripping structures and , during tissue fusion , is operatively connected to the tissue sections (G , G) , characterized in that the support structure has at least one additional physical functional structure for aiding or promoting the tissue fusion.16. The surgical tissue fusion instrument of claim 15 , characterized in that the physical functional structure has apertures or material weakenings in the support structure which are positioned in areas where the heat introduced by the heat-generating means passes through the support structure and the tissue sections (G claim 15 , G).17. The surgical tissue fusion instrument of claim 16 , characterized in that the apertures (D) are designed as linearly extending or circularly extending oblong holes.18. The surgical tissue ...

BOLT ADJUSTMENT DEVICE

A bolt adjustment device having a body, a clamping mechanism and an attachment point. The body extends in a longitudinal direction from a first end to a second end, the body having a cavity extending into the body in the longitudinal direction from the first end. The cavity can accommodate a thread during use of the bolt adjustment device. A step in the cavity is configured and arranged to engage with a nut when in use. A torque imparted on the attachment point will impart a torque to the bolt adjustment device. The clamping mechanism is attached to the attachment point such that the clamping mechanism clamps the nut in the cavity when torque is imparted on the clamping device. 1. A bolt adjustment device comprising:a body;a clamping mechanism; andan attachment point,wherein the body extends in a longitudinal direction from a first end to a second end, the body having:a cavity extending into the body in the longitudinal direction from the first end, the cavity being configured and arranged to accommodate a thread during use of the bolt adjustment device, anda step in the cavity at the first end, the step being configured and arranged to engage with a nut when in use;wherein the attachment point is configured to receive a torque imparted on the attachment point and to thereby impart a torque to the bolt adjustment device; andwherein the clamping mechanism is attached to the attachment point such that during use the clamping mechanism will clamp a nut in the cavity when a torque is imparted on the clamping device.2. The bolt adjustment device of claim 1 , in which the clamping mechanism comprises:a disc adjacent to the body at the second end, the disc comprising having:a face facing the second end of the body and a groove set into the face, the groove extending in a radial direction and a circumferential direction relative to the longitudinal direction; anda crank having:a first arm extending through the body from the first end to the second end, the first arm being ...

HF SURGICAL INSTRUMENT

An HF surgical instrument includes two instrument branches movable toward each other into a closing position. Each branch is equipped with at least one electrode and can be supplied with electric power from a power source. The HF instrument includes a separately configured bridge which is connectable to the power source via at least one electric connection or at least one electric line and includes at least one electrically conductive contact point for supplying the at least one electrode with electric power. The bridge can be introduced to at least one of the two branches so that the at least one contact point is electrically contacted by the at least one electrode. A method of assembling a HF surgical instrument includes equipping two instrument branches with at least one electrode. 1. A HF surgical instrument comprising:two instrument branches movable toward each other into a closing position, each instrument branch equipped with at least one electrode and can be supplied with electric power from a power source; anda separately configured bridge which is connectable to the power source via at least one electric connection or at least one electric line, the bridge including at least one contact point for supplying the at least one electrode with electric power, the bridge configured to be introduced to at least one of the two instrument branches such that the at least one contact point electrically contacts the at least one electrode.2. The HF surgical instrument according to claim 1 , wherein the at least one contact point of the bridge and/or the electrode has an electrically conductive spring contact element which causes an electrically conductive pressure contact between the contact point and the electrode.3. The HF surgical instrument according to claim 2 , wherein the bridge is introduced into the instrument branch and non-positively fixed in the instrument branch via the pressure contact between the at least one spring contact element and the at least one ...

2-HETEROARYL CARBOXAMIDES

The invention relates to novel 2-heteroaryl carboxamides and to the use thereof for producing medicaments for the treatment and/or prophylaxis of diseases and for improving perception, concentration, learning and/or memory. 118-. (canceled)20. The method of claim 19 , wherein the patient suffers from Alzheimer's disease or schizophrenia. The invention relates to novel 2-heteroaryl carboxamides, processes for their preparation, and their use for producing medicaments for the treatment and/or prophylaxis of diseases and for improving perception, concentration, learning and/or memory.Nicotinic acetylcholine receptors (nAChR) form a large family of ion channels which are activated by the messenger acetylcholine which is produced in the body (Galzi et al., 1995, 34, 563-582). A functional nAChR consists of five subunits which may be different (certain combinations of α1-9 and β1-4,γ,δ,ε subunits) or identical (α7-9). This leads to the formation of a diversity of subtypes which differ in the distribution in the muscles, the nervous system and other organs (McGehee et al., 1995, 57, 521-546). Activation of nAChR leads to influx of cations into the cell and to stimulation of nerve cells or muscle cells. Selective activation of individual nAChR subtypes restricts this stimulation to the cell types which have a corresponding subtype and is thus able to avoid unwanted side effects such as, for example, stimulation of nAChR in the muscles. Clinical experiments with nicotine and experiments in various animal models indicate that central nicotinic acetylchloline receptors are involved in learning and memory processes (e.g. Rezvani et al., 2001, 49, 258-267). Nicotinic acetylcholine receptors of the alpha7 subtype (α7 nAChR) have a particularly high concentration in regions of the brain which are important for learning and memory, such as the hippocampus and the cerebral cortex (Séguéla et al., 1993, 13, 596-604). The α7 nAChR has a particularly high permeability for calcium ions, ...

ELECTROSURGICAL INSTRUMENT WITH CLAMPING PRESSURE CONTROL FOR ELECTRODE BRANCHES

A surgical instrument in HF design includes two tissue branches, at least one of the tissue branches being movable relative to the other tissue branch and being able to be applied to the other tissue branch with a predetermined or predeterminable contact pressure via an actuation mechanism while clamping body tissue between the tissue branches. A clamping pressure controlling or adjustment device is interconnected in a force or torque gear train between the actuation mechanism and the at least one movable tissue branch. 112.-. (canceled)13. A surgical instrument in HF design comprising:an actuation mechanism;two tissue branches, at least one of the tissue branches being a movable tissue branch that is moveable relative to the other tissue branch and able to be applied to said other tissue branch with a predetermined or predeterminable contact pressure via the actuation mechanism while clamping body tissue between the tissue branches; anda clamping pressure controlling or adjustment device which is interconnected in a force or torque gear train between the actuation mechanism and the at least one movable tissue branch or within the actuation mechanism.14. The surgical instrument according to claim 13 , wherein the clamping pressure controlling or adjustment device comprises an elastically yielding lifting cylinder whose elastic resilience can be adjusted in the axial direction.15. The surgical instrument according to claim 13 , wherein the clamping pressure controlling or adjustment device comprises an energy accumulator which can be loaded through the actuation mechanism by a defined/definable amount or which can be loaded within a defined/definable range of the amount claim 13 , in which an actuation force or actuation moment resulting therefrom and transmitted by the force or torque gear train produces the predetermined or predeterminable contact pressure.16. The surgical instrument according to claim 15 , wherein the energy accumulator is an axially acting ...

ANASTOMOSIS INSTRUMENT WITH PIVOTABLE ANVIL

An anastomosis instrument includes a headpiece shaft which can be inserted in an instrument shaft so as to be axially shiftable therein, a plate-like and/or anvil-like headpiece being axially shiftable on the distal end portion of the headpiece shaft and being supported via a cross pin between a processing position and a withdrawal position, the headpiece on the headpiece shaft being displaced or shifted from a first, proximally retracted latching position in which the headpiece shaft is coupled to the headpiece in a form-fitting manner to fix the headpiece in the processing position so that it is unable to pivot, to a second, distally advanced latching position in which the form fit is released in order to allow the headpiece to swivel to the withdrawal position. 114.-. (canceled)15. An anastomosis instrument comprising:a headpiece shaft which can be inserted in an instrument shaft so as to be axially shiftable therein; anda plate-like and/or anvil-like headpiece being axially shiftable on a distal end portion of the headpiece shaft and being supported via a cross pin between a processing position and a withdrawal position,the headpiece on the headpiece shaft being displaceable or shiftable from a first, proximally retracted latching position in which the headpiece shaft is coupled to the headpiece in a form-fitting manner to fix the headpiece in the processing position so that it is unable to pivot, to a second, distally advanced latching position in which the form fit is released in order to allow the headpiece to pivot to the withdrawal position,the headpiece comprising an electrode on its proximal side facing the headpiece shaft, wherein the electrode is provided at the plate-like and/or anvil-like part of the headpiece which part is axially shiftable and pivotable.16. The anastomosis instrument according to claim 15 , wherein the cross pin is movably guided in an axially extending longitudinal slit so as to be able to be moved back and forth between the two ...

N-BIARYLAMIDES

The invention relates to N-biarylamides, methods for production and use thereof for the production of medicaments for the treatment and/or prophylaxis of diseases and for improvement in cognition, concentration power, learning power and/or memory. 111-. (canceled)13. The method of claim 12 , wherein the neurodegenerative disorder is Parkinson's disease.14. The method of claim 13 , further comprising co-administering a second active ingredient for the treatment of the patient suffering from Parkinson's disease.15. The method of claim 12 , wherein the administering is by an oral claim 12 , transdermal claim 12 , parenteral or inhalation route.16. The method of claim 12 , wherein the compound is selected from the group consisting of:[(4′-{[(3R)-1-Azabicyclo[2.2.2]oct-3-ylcarbonyl]amino}biphenyl-4-yl)amino]-(oxo)acetic acid hydrochloride;(3R)—N-{4′-[(Methylsulfonyl)amino]biphenyl-4-yl}quinuclidine-3-carboxamide hydrochloride;(3R)—N-{3′-[(Methylsulfonyl)amino]biphenyl-4-yl}quinuclidine-3-carboxamide hydrochloride;(3R)—N-{4′-[(Ethylsulfonyl)amino]biphenyl-4-yl}quinuclidine-3-carboxamide hydrochloride;(3R)—N-{4′-[(Phenylsulfonyl)amino]biphenyl-4-yl}quinuclidine-3-carboxamide hydrochloride;(3R)—N-{4′-[(Benzylsulfonyl)amino]biphenyl-4-yl}quinuclidine-3-carboxamide;(3R)—N-[4′-(Amino sulfonyl)biphenyl-4-yl]quinuclidine-3-carboxamide hydrochloride;(3R)—N-(4′-[(Isopropylamino)sulfonyl]biphenyl-4-yl)quinuclidine-3-carboxamide hydrochloride;(3R)—N-{4′-[(Benzylamino) sulfonyl]biphenyl-4-yl}quinuclidine-3-carboxamide hydrochloride;(3R)—N-(4′-{[(Methylamino)carbonyl]amino}biphenyl-4-yl)quinuclidine-3-carboxamide;(3R)—N-(4′-{([(Cyclopentylamino)carbonyl]amino}biphenyl-4-yl)quinuclidine-3-carboxamide hydrochloride;(3R)—N-(4′-{([(Ethylamino)carbonyl]amino}biphenyl-4-yl)quinuclidine-3-carboxamide;(3R)—N-{4′-({[(3-Methoxyphenyl)amino}carbonyl}amino)biphenyl-4-yl]quinuclidine-3-carboxamide hydrochloride;(3R)—N-{4′-[(3-Chlorobenzoyl)amino]biphenyl-4-yl}quinuclidine-3-carboxamide ...

N-BIARYLAMIDES

The invention relates to N-biarylamides, methods for production and use thereof for the production of medicaments for the treatment and/or prophylaxis of diseases and for improvement in cognition, concentration power, learning power and/or memory. 111-. (canceled)13: The method of claim 12 , further comprising co-administering a second active ingredient for the treatment of the mild cognitive impairment.14: The method of claim 12 , wherein the administering is by an oral claim 12 , transdermal claim 12 , parenteral or inhalation route.15: The method of claim 12 , wherein the compound of Formula (I) is selected from the group consisting of:[(4′-{[(3R)-1-Azabicyclo[2.2.2]oct-3-ylcarbonyl]amino}biphenyl-4-yl)amino]-(oxo)acetic acid hydrochloride;(3R)—N-{4′-[(Methylsulfonyl)amino]biphenyl-4-yl}quinuclidine-3-carboxamide hydrochloride;(3R)—N-{3′-[(Methylsulfonyl)amino]biphenyl-4-yl}quinuclidine-3-carboxamide hydrochloride;(3R)—N-{4′-[(Ethylsulfonyl)amino]biphenyl-4-yl}quinuclidine-3-carboxamide hydrochloride;(3R)—N-{4′-[(Phenylsulfonyl)amino]biphenyl-4-yl}quinuclidine-3-carboxamide hydrochloride;(3R)—N-{4′-[(Benzylsulfonyl)amino]biphenyl-4-yl}quinuclidine-3-carboxamide;(3R)—N-[4′-(Aminosulfonyl)biphenyl-4-yl]quinuclidine-3-carboxamide hydrochloride;(3R)—N-(4′-[(Isopropylamino)sulfonyl]biphenyl-4-yl)quinuclidine-3-carboxamide hydrochloride;(3R)—N-{4′-[(Benzylamino)sulfonyl]biphenyl-4-yl}quinuclidine-3-carboxamide hydrochloride;(3R)—N-(4′-{[(Methylamino)carbonyl]amino}biphenyl-4-yl)quinuclidine-3-carboxamide;(3R)—N-(4′-{([(Cyclopentylamino)carbonyl]amino}biphenyl-4-yl)quinuclidine-3-carboxamide hydrochloride;(3R)—N-(4′-([(Ethylamino)carbonyl]amino) biphenyl-4-yl)quinuclidine-3-carboxamide;(3R)—N-[4′-({[(3-Methoxyphenyl)amino]carbonyl}amino)biphenyl-4-yl]quinuclidine-3-carboxamide hydrochloride;(3R)—N-{4′-[(3-Chlorobenzoyl)amino]biphenyl-4-yl}quinuclidine-3-carboxamide hydrochloride;(3R)—N-{4′-[(3-Fluorobenzoyl)amino]biphenyl-4-yl}quinuclidine-3-carboxamide hydrochloride;( ...

AZABICYCLIC CARBAMATES AND THEIR USE AS ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTOR AGONISTS

The invention relates to novel benzothiophene-, benzofuran-, and indole ureas and to the use thereof for producing medicaments for the treatment and/or prophylaxis of diseases and for improving perception, concentration, learning, and/or memory. 115-. (canceled)17. The process of claim 16 , wherein:{'sup': '1', 'Ris 1-azabicyclo[2.2.2]oct-3-yl;'}{'sup': '2', 'Ris hydrogen;'}{'sup': '3', 'Ris hydrogen;'}{'sup': '4', 'Ris hydrogen;'}{'sup': '5', 'Ris hydrogen;'}{'sup': '6', 'sub': 1', '6', '3', '8', '6', '10, 'claim-text': {'sub': 1', '6', '1', '6', '1', '6', '6', '10', '1', '6', '1', '6', '1', '6', '1', '6, 'wherein (ii) is optionally substituted by phenyl, or C-C-alkoxy, and (iv) and (v) are optionally substituted by up to 3 radicals selected independently of one another from the group of C-C-alkyl, C-C-hydroxyalkyl, 3- to 8-membered heterocyclyl, C-C-aryl, 5- to 10-membered heteroaryl, hydroxy, halogen, cyano, C-C-alkoxy, C-C-acyl, trifluoromethyl, trifluoromethoxy, nitro, amino, C-C-alkylamino, or C-C-acylamino;'}, 'Ris (i) hydrogen, (ii) C-C-alkyl, (iii) C-C-cycloalkyl, (iv) C-C-aryl, or (v) 5- to 10-membered heteroaryl,'}A is sulfur;X is oxygen, andthe ring B is benzo.18. The process of claim 16 , wherein:{'sup': '1', 'Ris 1-aza-bicyclo[2.2.2]oct-3-yl;'}{'sup': '2', 'Ris hydrogen;'}{'sup': '3', 'Ris hydrogen;'}{'sup': '4', 'Ris hydrogen;'}{'sup': '5', 'Ris hydrogen;'}{'sup': '6', 'sub': 1', '4', '5', '6', '6', '10, 'claim-text': {'sub': 1', '4', '1', '3', '1', '4', '1', '4', '6', '10', '1', '3', '1', '3', '1', '3', '1', '3, 'wherein (ii) is optionally substituted by phenyl, C-C-alkoxycarbonyl or C-C-alkoxy, and (iv), (v) and (vi) are optionally substituted by up to 3 radicals selected independently of one another from the group of C-C-alkyl, C-C-hydroxyalkyl, 3- to 8-membered heterocyclyl C-C-aryl, 5- to 10-membered heteroaryl, hydroxy, fluorine, chlorine, cyano, C-C-alkoxy, C-C-acyl, trifluoromethyl, trifluoromethoxy, nitro, amino, C-C-alkylamino, or C-C- ...

Propylene polymer composition with improved balance of mechanical and optical properties

The invention relates to a propylene polymer composition comprising a random propylene-α-olefin copolymer, the α-olefin being ethylene and/or one or more C 4 -C 10 α-olefins, having a total α-olefin content ≥ 12.0 mol%, preferably ≥ 15.0 mol% and exhibiting a glass transition temperature of ≤ - 8 °C (according to DMTA, ISO 6721) with a broadness ΔT g of ≥ 55 °C, the random propylene-α-olefin copolymer comprising at least two distinct phases where the at least two phases are forming a co-continuous interpenetrating network structure. The invention further relates to a process for preparing the above-mentioned polymer compositions.

Propylene polymer composition with improved balance of mechanical and optical properties

The invention relates to a propylene polymer composition comprising a random propylene-α-olefin copolymer, the α-olefin being ethylene and/or one or more C 4 -C 10 α-olefins, having a total α-olefin content ≥ 12.0 mol%, preferably ≥ 15.0 mol%, the random propylene-α-olefin copolymer comprising at least two distinct phases where the at least two phases are forming a co-continuous interpenetrating network structure. The invention further relates to a process for preparing the above-mentioned polymer compositions.

Carrier for olefin polymerization catalysts

Trailer backup assist system with waypoint selection

A method of backing a trailer attached to a vehicle is provided herein. The method includes the steps of generating a plurality of waypoints on a display of the vehicle and selecting one of the plurality waypoints. The method also includes setting a trailer orientation for the selected waypoint and determining a backing path based on the selected waypoint and the set trailer orientation. The method further includes backing the trailer along the backing path.

Trailer backup assist system with predictive hitch angle functionality

A trailer backup assist system is provided herein. The system includes a calibration feature for calibrating an imaging device used for hitch angle detection. The system also employs multiple hitch angle detection methods, a number of which may run in parallel to increase the intervals at which a hitch angle can be measured. The system additionally includes a predictive feature in which a hitch angle can be predicted in instances where a trailer sensing device fails. The system is further configured to estimate a trailer length and generate steering commands that are invariant to the estimated trailer length under certain conditions.

Patent DE3910827C2

Limb volume accommodation in people with limb amputation

A prosthetic sock monitoring system is disclosed. The sock monitoring system includes a storage device and a data collection unit. The data collection unit is operable to receive data from at least one sensor coupled to a prosthetic sock that is wearable by a patient, and store the received data in the storage device. A prosthetic sock is also disclosed. The sock comprises material shaped to fit over at least a portion of the residual limb of the patient and a thickness adapted for inserting the residual limb into the socket of the prosthesis while the sock is fitted over the residual limb. The sock also comprises one or more of a sock identification unit and a force sensing device.

Vehicle air conditioning system

The invention relates to a vehicle air conditioning system, comprising a housing (2), an exhaust air path (9) and a plurality of inlet air paths (10), at least one exhaust air blower (11), at least one inlet air blower (13), at least one heating heat exchanger (16) disposed in the respective inlet air path (10) for heating the inlet air stream (14), at least one air conditioning heat exchanger (15) disposed in the respective inlet air path (10) for conditioning the inlet air stream (14), at least one exhaust air heat exchanger (15) disposed in the respective exhaust air path (9), at least one recirculating air path (18) which fluidically connects the exhaust air path (12) to a mixing zone (19) of the respective inlet air path (10), which mixing zone is disposed in the respective inlet air path (10) upstream of the respective heating heat exchanger (16) and upstream of the respective air conditioning heat exchanger (15), a control device (20) for controlling the cross-sections of the respective exhaust air path (9), of the respective inlet air path (10) and of the particular recirculating air path (18) through which the air can pass.

Method and system for repositioning of a flexible substrate

A material handling system includes a body including a first member and a second member. The first member and the second member define a hollow cavity within the body, and a gap disposed between the first member and the second member. The body is in flow communication with a first gas source to provide pressurized gas flow through the gap to generate a lifting force on an object placed adjacent to the body. The body has channels disposed within a central region of the body in flow communication with a second gas source. The channels are arranged to controllably disengage the object from the body.

Particle source for generating a particle beam and particle-optical device

Eine Teilchenquelle zur Erzeugung eines Teilchenstrahls 51 umfasst einen Teilchenemitter 17a, eine erste Platte 31, einen ersten Ablenker 53 und eine zweite Platte 43 mit einer Öffnung 45. Die erste Platte hat eine kleinere Öffnung 33, hinter der ein erster Strahl 39 gebildet wird und eine größere Öffnung 37, hinter der ein zweiter Strahl 41 gebildet wird. Eine Steuerung 11a stellt in einem ersten Betriebsmodus den Ablenkwinkel des Ablenkers so ein, dass Teilchen des ersten Strahls die Öffnung 45 in der zweiten Platte durchsetzen und den von der Teilchenquelle erzeugten Teilchenstrahl 51 bilden, und sie stellt in einem zweiten Betriebsmodus den Ablenkwinkel so ein, dass Teilchen des zweiten Strahls 41 die Öffnung 45 in der zweiten Platte 43 durchsetzen und den von der Teilchenquelle erzeugten Teilchenstrahl 51 bilden.

Trajectory planner for a trailer backup assist system

In one embodiment of the disclosed subject matter, a trailer backup assist system includes a state estimator that determines a current position of a trailer relative to a waypoint position. In addition, the trailer backup assist system includes a trajectory planner that generates first and second circular trajectories tangent to one another spanning between the current and waypoint positions. The trailer backup assist system also includes a controller that reverses the trailer to the waypoint position along the first and second circular trajectories, which are dynamically regenerated as the trailer reverses along the first circular trajectory.

Trailer backup assist system with off-shoot correction

A trailer backup assist system for a vehicle reversing a trailer is provided herein. The system includes a steering input device for controlling a desired curvature. A controller is in communication with the steering input device and is configured to generate steering command for the vehicle to guide the vehicle and trailer onto a straight path when a straight backup request is initiated via the steering input device.

Method of inputting a path for a vehicle and trailer

A method of inputting a path is provided. The method includes the steps of generating an aerial view of a vehicle and a trailer based on at least one of image data and satellite image data, displaying the aerial view on a display having a touch screen, and registering a touch event on the touch screen that inputs an intended path for the vehicle and the trailer.

Control for trailer backup assist system

In one embodiment of the disclosed subject matter, a trailer backup assist system includes a sensor that senses a measured hitch angle between a vehicle and a trailer. The system also provides an input module that receives a desired curvature of the trailer. A controller of the system includes a curvature regulator determining a desired hitch angle based on the desired curvature and a steering angle of the vehicle. In addition, the controller of the system includes a hitch angle regulator generating a steering angle command based on the desired hitch angle and the measured hitch angle. In this embodiment, the controller is configured to operate the trailer backup assist system irrespective of the attached trailer having a conventional tongue or a gooseneck tongue.

Trailer backup assist system with waypoint selection

A display system for a vehicle attached to a trailer is provided herein. The system includes a display configured to show an aerial view of the vehicle and the trailer and a plurality of waypoints, each indicating a possible parking location for the trailer. The system also includes a device that interfaces with the display and is operable to select one of the plurality of waypoints and set a trailer orientation for the selected waypoint.

Trailer backup assist system with trajectory planner for multiple waypoints

A trailer backup assist system, according to one embodiment, includes a state estimator that determines a current position of a trailer relative to a plurality of waypoints. A trajectory planner may then incrementally generate a path from the current position to the plurality of waypoints. The trajectory planner has a first mode that generates first and second circular trajectories tangent to one another connecting between the current position and a waypoint of the plurality of waypoints. A second mode of the trajectory planner generates the second circular trajectory between the current position and the waypoint after the trailer traverses the first circular trajectory. Also, a third mode of the trajectory planner switches to the first operating mode when the trailer reaches the waypoint for guidance to a subsequent waypoint. A curvature controller guides the trailer based on a curvature of the respective first or second circular trajectories.

Speed optimized trajectory control for motor vehicles

A trailer backup assist system for motor vehicles includes an auxiliary user input feature that can be used by a vehicle operator to provide a steering curvature command corresponding to a desired vehicle path curvature without requiring a user to move a steering wheel of the motor vehicle. The trailer backup assist system is configured to control a vehicle speed while the vehicle is backing up with a trailer attached thereto utilizing an input comprising at least one of a steering curvature command and an angle of a trailer relative to the vehicle. The trailer backup assist system controls at least one of a brake system, an engine torque, and a transmission gear selection to thereby control vehicle speed in a reverse direction.

Trailer curvature control and mode management with powertrain and brake support

A backup assist system for a vehicle reversing a trailer includes a brake module and a throttle module. The system further includes a controller having a vehicle speed detector and coupled with the brake module and the throttle module for implementing a backup mode including detecting an adverse operating condition and then adjusting at least one of the brake module and the throttle module and terminating the backup mode upon detecting the adverse operating condition for a time interval.

Speed limiting comfort enhancement

A vehicle includes a steering system, a vehicle speed detector, a brake system, and a control system. The control system is coupled with steering system for implementing a backup mode for reversing a trailer including controlling the steering system to maintain the trailer along a path. The control system is further coupled with the speed detector and the brake system and selectively outputs a rate-limited brake torque demand to the brake system to maintain a vehicle speed below a threshold speed.

Inertial reference for TBA speed limiting

A method of controlling a vehicle while the vehicle is backing up with a trailer attached thereto. The vehicle may include a brake system and a power train system. The method includes determining a trailer yaw rate, and estimating a modified trailer curvature. The modified trailer curvature comprises a ratio of the trailer yaw rate to the vehicle speed. The method further includes determining a maximum allowable vehicle speed as a function of modified trailer curvature utilizing predefined criteria that defines a maximum allowable vehicle speed for a given modified trailer curvature. The method further includes limiting the vehicle speed such that the maximum allowable vehicle speed is not exceeded.

Ethanol-free microemulsion perfuming compositions.

Method for monitoring the taking of medicines

Patient monitoring system, has a manual scanner to register the drug data for storage in a memory, with an electronic unit to determine adverse effects and contraindications. Patient monitoring system, has a manual scanner to register the drug data for storage in a memory, with an electronic unit to determine adverse effects and contra-indications. For the system to monitor the administration of medications by a patient (1), as each medication is taken for use it is passed manually through a scanner (5) where the machine readable data can be registered. The scanned data are passed to an electronic unit (8) with a memory (6) where the nature of the medication and its time of administration can be accessed. The machine readable data can be a code which is optically scanned, and especially a barcode (4) on the packaging blister, leaflet or package (2). The code can also be an optical, electronic or magnetic code on a code carrier (3) at the medication, as a code chip card.

PROCEDURE FOR B-AVERMECTIN PREPARATION

CONTINUOUS GRAVIMETRIC DOSING APPARATUS FOR INTEGRATING IN A PNEUMATIC TRANSPORT CIRCUIT FOR SEMI-FLUID PRODUCTS

L'INVENTION SE RAPPORTE AUX APPAREILS DE PESAGE ET DE MANUTENTION. L'APPAREIL SELON L'INVENTION EST DU TYPE DANS LEQUEL UN COURANT DE PRODUIT EST TRANSPORTE SUR UN CERTAIN PARCOURS EN MEME TEMPS QU'IL SOLLICITE UN DISPOSITIF DYNAMOMETRIQUE, LE DEBIT ETANT CALCULE PAR MULTIPLICATION DE LA CHARGE INSTANTANEE PAR LA VITESSE DE TRANSPORT. ICI, LE DISPOSITIF DE TRANSPORT EST UN ROTOR1 A AXE VERTICAL, MUNI DE POCHES13 QUI PASSENT SUCCESSIVEMENT SOUS UNE OUVERTURE DE CHARGEMENT ET SUR UNE OUVERTURE DE DECHARGEMENT DU CARTER. LE CARTER OSCILLE AUTOUR D'UN AXE16 ET EST SUSPENDU DE L'AUTRE COTE A UN DISPOSITIF DYNAMOMETRIQUE17 TRAVAILLANT SENSIBLEMENT SANS DEPLACEMENT. UNE GENERATRICE TACHYMETRIQUE67 MESURE LA VITESSE ANGULAIRE DU ROTOR. LES RACCORDEMENTS CONNECTES A L'INSTALLATION DE TRANSPORT PNEUMATIQUE SONT PLACES DANS LE PLAN VERTICAL DE L'AXE16. PRINCIPALE APPLICATION: DOSAGE DE PRODUITS PULVERULENTS DEVANT ETRE TRANSPORTES SANS CONTACT AVEC L'ATMOSPHERE AMBIANTE (CHARBON PULVERISE, DIVERS PRODUITS CHIMIQUES, PHARMACEUTIQUES, ALIMENTAIRES, ETC...)

DYNAMOMETRIC CELL WITH GYROSCOPE

L'INVENTION SE RAPPORTE AUX DYNAMOMETRES A GYROSCOPE. UNE FORCE QUI S'APPLIQUE SUR L'AXE DE ROTATION R DU GYROSCOPE ENGENDRE UN MOUVEMENT DE PRECESSION, DONT LA VITESSE EST PROPORTIONNELLE A LA FORCE. LE CAPTEUR DE CHARGE 16 QUI N'ACCOMPAGNE PAS LA PRECESSION AGIT PAR L'INTERMEDIAIRE D'UN ORGANE D'INTRODUCTION DE LA FORCE ACCOMPAGNANT LA PRECESSION, MONTE DANS UN PALIER 12 SUR L'AXE DE PRECESSION. SELON L'INVENTION, LE PALIER 12 EST ARTICULE SUR LA CARCASSE 1 PAR DES BIELLETTES 14 POUR SE DEPLACER COAXIALEMENT A L'AXE DE PRECESSION P. UN ARBRE 9 QUI TOURILLONNE DANS LE PALIER 12 EST MUNI D'UN BRAS DE CHARGE 10 ET UN ELEMENT 11 RELIE LE BRAS 9 AU CERCLE DE CARDAN INTERIEUR 7, LE BRAS 9, L'ELEMENT 11, L'AXE DE ROTATION ET L'AXE DE PRECESSION SE TROUVANT SENSIBLEMENT DANS UN MEME PLAN. APPLICATION : MESURE DES FORCES. THE INVENTION RELATES TO GYROSCOPE DYNAMOMETERS. A FORCE WHICH IS APPLIED ON THE ROTATION AXIS R OF THE GYROSCOPE GENERATES A PRECESSIONAL MOVEMENT, THE SPEED OF WHICH IS PROPORTIONAL TO THE FORCE. THE LOAD SENSOR 16 WHICH DOES NOT ACCOMPANY THE PRECESSION ACTS THROUGH A FORCE INTRODUCTION ORGAN ACCOMPANIING THE PRECESSION, MOUNTED IN A LEVEL 12 ON THE PRECESSION AXIS. ACCORDING TO THE INVENTION, THE BEARING 12 IS ARTICULATED ON THE CARCASE 1 BY LINKAGE RODS 14 TO MOVE COAXIALLY WITH THE PRECESSION SHAFT P. A SHAFT 9 WHICH IS DRIVED IN THE BEARING 12 IS EQUIPPED WITH A LOAD ARM 10 AND A ELEMENT 11 CONNECTS THE ARM 9 TO THE INTERNAL CARDAN CIRCLE 7, THE ARM 9, THE ELEMENT 11, THE ROTATION AXIS AND THE PRECESSION AXIS SENSITIVELY LOCATED IN THE SAME PLANE. APPLICATION: MEASUREMENT OF FORCES.

HEATER COMPRISING A HEAT PUMP FLUID AND AN ABSORBABLE OR ADSORBABLE GAS AND A POROUS MATERIAL

Method for an optoelectronic sensor

Compression system for cooling and heating purposes.

Tool and process for handling pliant comestibles

A tool and process for handling a pliant comestible are disclosed. The tool includes a tool body including a recessed mold and a plurality of cavities. The tool body is configured to position the pliant comestible and retain the pliant comestible within the recessed mold.

PISTON ARRANGEMENT FOR A PNEUMATIC OR HYDRAULIC CYLINDER

CET AGENCEMENT EST DU TYPE DE CEUX QUI COMPORTENT UNE TIGE DE PISTON 1, UN CORPS DE PISTON 7 EN MATIERE PLASTIQUE, QUI EST FIXE SUR UNE ZONE DE RETENUE 2 DE LADITE TIGE ET REMPLIT UNE DOUBLE FONCTION DE SUPPORT ET D'ETANCHEITE, ET UN JOINT DE PISTON MONTE SUR LE CORPS, QUI PRESENTE DEUX LEVRES ANNULAIRES ORIENTEES EN SENS INVERSE L'UNE DE L'AUTRE. IL EST CARACTERISE EN CE QUE LES LEVRES 9, 10 ONT UNE FORME TRONCONIQUE DIVERGEANT VERS L'EXTERIEUR SOUS UNE TENSION INITIALE ELASTIQUE, EN CE QUE LE CORPS 7 COMPORTE UN TRONC 13 CYLINDRIQUE, DONT LES FACES EN BOUT 14, 15 DEPASSENT DANS LE SENS AXIAL, DES EXTREMITES DES LEVRES ET FORMENT TAMPON POUR L'IMPACT DU PISTON DANS LES POSITIONS EXTREMES DE SA COURSE ET EN CE QU'UN ESPACE ANNULAIRE 11, 12 EST MENAGE ENTRE LE TRONC ET CHAQUE LEVRE. THIS ARRANGEMENT IS OF THE TYPE OF THOSE WHICH INCLUDE A PISTON ROD 1, A PISTON BODY 7 IN PLASTIC MATERIAL, WHICH IS FIXED ON A RETAINING ZONE 2 OF THE SAID ROD AND FULFILLS A DUAL FUNCTION OF SUPPORT AND SEALING, AND A BODY-MOUNTED PISTON SEAL, WHICH PRESENTS TWO ANNULAR LIPS ORIENTED IN REVERSE DIRECTION OF ONE OF THE OTHER. IT IS CHARACTERIZED IN THAT THE LIPS 9, 10 HAVE A TRUNCONIC SHAPE DIVERTING OUTWARDS UNDER AN INITIAL ELASTIC TENSION, IN THAT THE BODY 7 HAS A 13 CYLINDRICAL TRUNK, THE END FACES 14, 15 OF WHICH EXTEND IN THE DIRECTION AXIAL, ENDS OF THE LIPS AND FORM BUFFER FOR THE IMPACT OF THE PISTON IN THE EXTREME POSITIONS OF ITS STROKE AND IN THAT AN ANNULAR SPACE 11, 12 IS CLEARED BETWEEN THE TRUNK AND EACH LIP.

Conveyor system

A conveyor system, in particular a suspension conveyor system, comprising at least two transport units adapted to be moved on rollers and interconnected by a disconnectable coupling, the coupling including two identically formed hooks which are each provided with a hook opening, one of said hooks being arranged by an associated base member on one of the transport units to be coupled and the other hook being arranged by an associated base member on the other transport unit to be coupled in such a way that their hook openings face each other, each hook being loaded by a spring and being connected to its associated base member by means of a hub for rotation about an axis coinciding with a centerline of the hub, each hub forming a locking member by, in a coupled condition, being adapted to be engaged by the hook opening of the hook not associated with said transport unit while the hooks, in an uncoupled condition, being adapted to engage each other, and to be rotated by this engagement under tensioning of the spring, when the two transport units being moved towards each other, until each hook opening faces on hub in order to allow the spring to rotate the hook opening into a locking engagement with the hub.

A MULTIPLE LAYER PACKAGING FOR A SPRAY CONTAINER CLOSURE

Process for the preparation of glycosides

Method for operating an optical sensor, particularly a code reader and a code reader

The optical sensor receives reflected or remitted light and generates a corresponding image whose content is read. At least some images are compressed in the sensor using a compression algorithm. The method involves compressing and storing only images corresponding to a faulty reading. The compressed images contain an objector code to be read and an object environment AN Independent claim is also included for the following: (a) a code reader.

VALVE LINE OF AN AEROSOL VESSEL WITH AN IMPROVED SEAL

CONTINUOUS GRAVIMETRIC DOSING APPARATUS FOR INTEGRATING INTO A PNEUMATIC TRANSPORT CIRCUIT FOR SEMI-FLUID PRODUCTS

Gasket for an aerosol valve stem

Resilient cable drum

A drum for the winding and storage of cable or wire comprising a core and a pair of flanges flanking the ends of the core. The marginal portion of each flange is surrounded by a resilient, nondeformable ring of metal or synthetic plastic which intercepts impact and shock forces applied to the edges of the flanges, thereby protecting the drum from damage.

Gasket for an aerosol valve stem

Operating method for solar heat-transfer medium circuit, by switching auxiliary heat source on as soon as the actual temperature in the solar heat accumulator falls below a predefined daily temperature range

An auxiliary heat source (2) is switched on as soon as the actual temperature in the solar heat accumulator (3) falls below a predefined daily temperature range. The temperature range starts at a lower level during sunrise, increases during midday, and then lowers while nearing sunset.

System and method for reconstructing lost data in a storage system

A system (and method) for determining reconstruction formulas for partial strip reconstruction in a storage system in which a plurality of lost strips have been detected, includes using a combination of a direct reconstruction method and a sequential reconstruction method.

Method and apparatus for reading a bar code

The front, center and rear portions (7,9,11) of a picture are photographed using a matrix camera. A bar of the barcode is associated with front and center portions, and another bar of barcode is associated with center and rear portions. The reconstruction of information encoded by a barcode is performed by putting together the portions of picture in a reconstruction buffer to form a complete image of the barcode. An independent claim is also included for machine-readable barcode reading apparatus.

Heat pump circuit based around a refrigeration unit in a sealed housing

The heat pump consists of a refrigerator circuit with a housing.The cooler has a compressor, condenser, restrictorand an evaporator. The evaporator and compressor connections couple with a heat exchanger within heat and sound isolation material.

Process for the production of b avermectins and cultures therefor

Process for preparing copolymers of trioxane

FUEL INJECTION SYSTEM FOR INTERNAL COMBUSTION ENGINES

HEATER COMPRISING A HEAT PUMP FLUID AND AN ABSORBABLE OR ADSORBABLE GAS AND A POROUS MATERIAL

La présente invention concerne un caloduc comprenant une enceinte hermétique contenant : - un condenseur ; - un matériau poreux adsorbant ou absorbant ; - un évaporateur ; - un fluide caloporteur condensable en conditions d'opération du caloduc ; - un gaz adsorbable ou absorbable par le matériau poreux, distinct du fluide caloporteur, dont la température de condensation est supérieure à la température de condensation du fluide caloporteur dans les conditions d'opération du caloduc. The present invention relates to a heat pipe comprising a hermetic enclosure containing: - a condenser; a porous adsorbent or absorbent material; an evaporator; a heat transfer fluid which can be condensed under operating conditions of the heat pipe; an adsorbable or absorbable gas by the porous material, distinct from the coolant, the condensation temperature of which is higher than the condensation temperature of the heat transfer fluid under the operating conditions of the heat pipe.

STEEL CABLE

A method for identification, isolation and production of antigens to a specific pathogen

Described is a method for identification, isolation and production of hyperimmune serum-reactive antigens from a specific pathogen, a tumor, an allergen or a tissue or host prone to autoimmunity, said antigens being suited for use in a vaccine for a given type of animal or for humans, which is characterized by the following steps: - providing an antibody preparation from a plasma pool of said given type of animal or from a human plasma pool or individual sera with antibodies against said specific pathogen, tumor, allergen or tissue or host prone to auto-immunity, - providing at least one expression library of said specific pathogen, tumor, allergen or tissue or host prone to auto-immunity, - screening said at least one expression library with said antibody preparation, - identifying antigens which bind in said screening to antibodies in said antibody preparation, - screening the identified antigens with individual antibody preparations from individual sera from individuals with antibodies against said specific pathogen, tumor, allergen or tissue or host prone to auto-immunity, - identifying the hyperimmune serum-reactive antigen portion of said identified antigens and which hyperimmune serum-reactive antigens bind to a relevant portion of said individual antibody preparations from said individual sera and - optionally isolating said hyperimmune serum-reactive antigens and producing said hyperimmune serum-reactive antigens by chemical or recombinant methods.

Fuel distributor.

Fuel injection nozzle for internal combustion engine

The nozzle comprises a valve needle (14) and an induction coil (30) which sends signals conditioned by the speed of the needle (14) to an evaluation circuit of the injection nozzle. The coil (30) cooperates with an armature (34, 34a) associated to the needle (14) and with a coil core (39, 39a), which delimit therebetween an air gap. A permanent magnet body (40, 40a) is associated with the coil core (39) or the armature (34a), and its magnetic field passes through the air gap between the armature (34, 34a) and the core (39, 39a). The modifications of the magnetic field of the magnetic body (40, 40a) caused by a change in the air gap width induce in the coil (30) electric signals which render superfluous the application of a voltage to the coil (30) from the control apparatus.

surgical instrument preferably under construction of type hf

Gear train unit and arrangement for a stamping press

Preparation of solid capsules comprising aromas

Un procedimiento de preparación de cápsulas sólidas, en el que el procedimiento comprende las etapas de: a) preparar una emulsión que comprende - del 0,1 al 10% de un extracto natural que comprende saponinas; - del 5 al 55% de un biopolímero soluble en agua que tiene un peso molecular inferior a 100 kDa; - del 5 al 60% de aroma o perfume; y - del 15 al 80% de agua; en el que los porcentajes se definen en peso, con respecto al peso total de la emulsión; b) secar mediante pulverización la emulsión obtenida en la etapa a) para obtener cápsulas sólidas.

Method and arrangement for defrosting a heat exchanger (evaporator) in a steam compression system.

A Method for Identification, Isolation and Production of Antigens to a Specific Pathogen

Particle source for producing a particle beam and particle-optical apparatus

A particle source for producing a particle beam includes a particle emitter, a first plate, a first deflector and a second plate with an aperture. The first plate has a smaller aperture, downstream of which a first beam is formed, and a larger aperture, downstream of which a second beam is formed. A controller sets the deflection angle of the deflector so that in a first mode of operation that particles of the first beam pass through the aperture in the second plate and form the particle beam produced by the particle source. The controller sets the deflection angle so that in a second mode of operation that particles of the second beam pass through the aperture in the second plate and form the particle beam produced by the particle source.

Modular multi-level converter with several cell group controllers per phase arm

There is provided a method (200) of controlling a plurality of converter cells (240) in a phase arm of a modular multilevel converter, MMC, in accordance with a main reference (210). The method includes dividing (212) the main reference into a plurality of reference parts (220), and, by using a grouping of the plurality of converter cells into a plurality of groups (250), operating a plurality of modulators in parallel, each modulator controlling a respective one of the groups of converter cells in accordance with one of the reference parts. A phase arm controlled in accordance with such a method is also provided, as well as an MMC including at least one such phase arm, and a converter station including at least one such MMC.

Process for the manufacture of cross-linked copolymers of trioxane

Cultures of Streptomyces avermitilis and method for producing B avermectins

Lamellar seal for a turbo machine

A lamellar seal for sealing a shaft which rotates around an axis, especially in a gas turbine, comprises a multiplicity of lamellae (13) which are spaced one beneath the other, arranged in a concentric circle around the axis, and fixed in their position, wherein the lamellae (13) by their surfaces are oriented essentially parallel to the axis. The lamellar seal is improved by the fact that the lamellae (13) have formed-on means (19, 20, 21) in each case for positioning and retaining the lamellae (13) in the lamellar seal (12), which means comprise one or more laterally projecting support arms (19, 20, 21) which engage in complementarily formed recesses (25, 26) of the end plates (15, 16).

Method and system for repositioning of a flexible substrate

A material handling system includes a body including a first member and a second member. The first member and the second member define a hollow cavity within the body, and a gap disposed between the first member and the second member. The body is in flow communication with a first gas source to provide pressurized gas flow through the gap to generate a lifting force on an object placed adjacent to the body. The body has channels disposed within a central region of the body in flow communication with a second gas source. The channels are arranged to controllably disengage the object from the body.

Corner latch cooler

A cooler is provided having latches secure a lid to a body of the cooler. The latches are affixed to corner portions the lid and the body. The comer portions may be recessed such that the latches do not protrude outside the footprint of the body of the cooler.

Offset local oscillator

ABSTRACT OF THE DISCLOSURE Apparatus utilizing single sideband techniques for generating a local oscillator signal of high spectral purity which is offset from a relatively wide-band signal generator frequency fg = 0.8 - 22OMHz by a con-stant IF frequency difference fo = 46KHz. The output signal is coupled from once of a plurality of phase locked oscillators having overlapping frequency ranges which act as active filters to obtain improved spectral purity.

DEVICE FOR INJECTING A FUEL-AIR MIXTURE FOR MULTI-CYLINDER INTERNAL COMBUSTION ENGINES

Welding machine with a wire feed device

PROCEDURE FOR B-AVERMECTIN PREPARATION

HAENGEFOERDERSYSTEM

Die Erfindung betrifft ein Haengefoerdersystem insbesondere fuer Spinnereibetriebe. Selbsttaetig bzw. ueberwiegend selbsttaetig arbeitende Haengefoerdersysteme zum Transport von Spulen arbeiten mit ganzen Zuegen, auf denen eine Mehrzahl von Spulen angeordnet sind. Damit musz jedoch, beispielsweise aus einer Ringspinnmaschine, der gesamte Zug ausgewechselt werden, wenn die erste der Spulen leer ist. Zur Vermeidung des dadurch anfallenden Abfalles und fuer eine groeszere Flexibilitaet der Bewegung der Spulen auch bei einem automatisierten bzw. weitgehend automatisierten Betrieb, werden im erfindungsgemaeszen Haengefoerdersystem Spulen verwendet, die mit ihrem eigenen Laufmittel ausgeruestet sind, das auch beim Einsetzen in Verarbeitungsmaschinen an der Spule verbleibt. Dadurch kann jede Spule sowohl einzeln aber auch im Zug gehandhabt werden. Das Haengefoerdersystem eignet sich besonders fuer eine Quereinfahrt in eine Ringspinnmaschine. Fig. 1{Haengefoerdersystem; Transport von Spulen; Ringspinnmaschine; Flexibilitaet der Bewegung der Spulen; automatisierter Betrieb; eigene Laufmittel; Quereinfahrt} The invention relates to a Haengefoerdersystem especially for spinning companies. Self-acting or predominantly self-acting Haengefoerdersysteme for transporting coils work with whole trains, on which a plurality of coils are arranged. But musz, for example, from a ring spinning machine, the entire train to be replaced when the first of the coils is empty. To avoid the resulting waste and for a greater flexibility of the movement of the coils even in an automated or largely automated operation, are used in the invention Haengefoerdersystem coils that are equipped with their own solvent, which remains even when inserted into processing machines on the coil , As a result, each coil can be handled both individually and on the train. The Haengefoerdersystem is particularly suitable for a cross entry into a ring spinning machine. Fig. 1 {Haengefoerdersystem; Transport of spools; ...

S. aureus antigene

SUSPENSION TRANSPORTATION SYSTEM.

There is described a suspended transport system for conveying bobbins (1) to predetermined bobbin positions (RSP) in a spinning machine, especially a ring spinning machine, which has a conveyor stage (3) which leads along the predetermined bobbin positions (RSP) and on which a driven conveyor train (4) equipped at least with a plurality of bobbins (1) can be transported. To transfer individual bobbins (1) from the conveyor stage (3) to the predetermined bobbin positions, a device (14, 14') movable along the spinning machine is provided. For the transfer of bobbins (1) into the ring spinning machine which can be carried out quickly and without difficulty, there is a bobbin carriage (14, 14') which is movable together with the conveyor train (4) and runs parallel to the conveyor stage (3) and on which is arranged a separating and guiding device (16, 30, 32) for transferring a separated bobbin (1) from the conveyor train (4) into a predetermined bobbin position (RSP). <IMAGE>

METHOD AND DEVICE FOR CONTROLLING AN INTERNAL COMBUSTION ENGINE

Method and computer system for operating at least two interconnected control devices

Method for operating a heat pump

Die Erfindung betrifft ein Verfahren zum Betrieb einer Wärmepumpe, bei dem ein dampfförmiges Kältemittel mit einem Verdichter (1) verdichtet wird, bei dem das verdichtete Kältemittel mit einem Kondensator (2) kondensiert wird, bei dem das kondensierte Kältemittel mit einem Expansionsventil (3) entspannt wird, bei dem das entspannte Kältemittel einem Sammler (4) zugeführt wird, wobei sich im Sammler (4) eine dampfförmige Phase des Kältemittels von einer flüssigen Phase des Kältemittels trennt, bei dem die flüssige Phase des Kältemittels einem Drosselelement (5) zugeführt und mit diesem weiter entspannt wird, bei dem die entspannte flüssige Phase des Kältemittels mit einem Verdampfer (6) verdampft wird, bei dem das verdampfte Kältemittel dem Verdichter (1) zugeführt wird. Nach der Erfindung ist vorgesehen, dass ein Maß der Überhitzung des Kältemittels vor Eintritt in den Verdichter (1) erfasst und dieses Maß der Überhitzung als Führungsgröße zur Regelung des Expansionsventils (3) verwendet wird. The invention relates to a method for operating a heat pump, in which a vaporous refrigerant is compressed with a compressor (1) in which the compressed refrigerant is condensed with a condenser (2) in which the condensed refrigerant is expanded with an expansion valve (3) is, in which the expanded refrigerant is supplied to a collector (4), wherein in the collector (4) separates a vapor phase of the refrigerant from a liquid phase of the refrigerant, wherein the liquid phase of the refrigerant to a throttle element (5) and supplied with This is further relaxed, in which the relaxed liquid phase of the refrigerant is evaporated with an evaporator (6), in which the evaporated refrigerant is supplied to the compressor (1). According to the invention it is provided that a measure of the overheating of the refrigerant before entry into the compressor (1) detected and this degree of overheating is used as a reference variable for controlling the expansion valve (3).

DEMETHYLAVERMECTINE AND MANUFACTURE THEREOF.