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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 14. Отображено 11.
28-03-2019 дата публикации

Assay Wells with Hydrogel as a Well-Contents Separator

Номер: US20190091691A1
Автор: Chatterjee Dev, Heffernan Michael John, III Leo, Linbeck
Принадлежит:

In a polymer assay cartridge having wells containing reagents, beads and sample, where the wells are covered (e.g., with Parafilm® or films) and shipped to the point of care, the reagents and well contents can leak out. The reagent solutions are made semi-solid by adding hydrogel reagents and cooling to form a gel. Preferably, the hydrogel is heated before an assay is conducted with the cartridge, and pigmented beads in the wells indicate melting or excessive heating, or congealing of the hydrogel, based on pigment color change 120-. (canceled)21. An assay device stable for shipment comprising:a plurality of wells which are a series of openings connected by first channels in a first surface of the body of the assay device, wherein said wells house assay reagents in solution, the wells include a gelatin hydrogel;at least one air gap in the first channels to separate fluids in the wells, wherein the gelled gelatin hydrogel prevents movement of the assay reagents from the wells into the air gap.22. The device of wherein the gelatin hydrogel is at least 150 Bloom.23. The device of wherein the gelatin hydrogel is less than 10% gelatin.24. The device of wherein the gelatin hydrogel is Bloom range 180-200.25. The device of wherein the gelatin hydrogel is at a concentration range of 1 to 4%.26. The device of wherein at least one of the wells also contains magnetic microbeads.27. The device of wherein second channels extending transverse to the first channels intersect the first channels.28. The device of wherein the second channels extend from the first surface through the body to its opposite surface.30. The device of wherein the wells are sealed using a plastic paraffin film covering substantially the first surface.31. The device of further including encoding the cartridge with a QR or other code.3229. The device of claim further including adhering a paper or polymer layer substantially covering said plastic paraffin film.33. The device of further including a QR or other ...

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Номер записи: 1
28-03-2019 дата публикации

Assay Wells with Hydrogel as a Well-Contents Separator and a Pigment-Based Temperature Indicator

Номер: US20190091692A1
Автор: Brad Ernest Munoz, Dev Chatterjee, Leo LlNBECK, III, Michael John Heffernan
Принадлежит: Fannin Partners LLC

In a polymer assay cartridge having wells containing reagents, beads and sample, where the wells are covered (e.g., with Parafilm® or films) and shipped to the point of care, the reagents and well contents can leak out. The reagent solutions are made semi-solid by adding hydrogel reagents and cooling to form a gel. Preferably, the hydrogel is heated before an assay is conducted with the cartridge, and pigmented beads in the wells indicate melting or excessive heating, or congealing of the hydrogel, based on pigment color change

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Номер записи: 2
13-04-2017 дата публикации

Automated Driving of an Assay

Номер: US20170102384A1
Автор: Dev Chatterjee, Leo LlNBECK, III, Michael John Heffernan
Принадлежит: Fannin Innovation Studio Inc

The invention herein relates to conducting assays with an apparatus including a substantially transparent assay cartridge loaded with magnetic beads, and a magnet carrier base positioned below a scanning platform holding the assay cartridge. The assay cartridge includes magnetic beads, sample and control solutions in some wells, and assay reagents in others. A microcomputer controls a DC motor which controls movement of the magnet carrier base, and causes the magnetic beads to travel from one well to another. An electromagnetic coil-spring assembly induces mixing of well contents with the magnetic beads on actuation. The assay cartridge is authenticated by sending its encoding to a server or website, and assay instructions are provided remotely to the microcomputer. Following assay completion, the cartridge can have color change or other assay indication detected, and the results sent to the server or website or another recipient.

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Номер записи: 3
26-04-2018 дата публикации

Automated Remotely Instructed Driving of an Assay

Номер: US20180111123A1
Автор: Chatterjee Dev, Heffernan Michael John, III Leo, LlNBECK, Varadhachary Atul
Принадлежит:

The invention relates to conducting assays with an apparatus including a substantially transparent assay cartridge loaded with magnetic beads, and a magnet carrier base positioned below a scanning platform holding the assay cartridge. A microcomputer controls a stepping motor which controls movement of the magnet carrier base, and causes the magnetic beads to travel from one well to another, where the wells contain different assay reagents. An electromagnetic coil-spring assembly induces mixing of well contents with the magnetic beads on actuation. The assay cartridge is authenticated by sending its encoded identifier to a server or website, and assay instructions are provided remotely to the microcomputer. Following assay completion, the cartridge can have color change or other assay indication detected, and the results sent to the server or website or another recipient. Concurrently assaying a control allows modification of assay results based on measured field conditions. 1. A method of providing instructions through the internet for performing a particular assay by using an encoded container housing assay reagents , where the instructions are executed by an assay driver which is actuated by the instructions to cause a first set of magnetic beads to contact at least one control added to the encoded container , and to cause other magnetic beads to contact at least one sample and to move each set of magnetic beads through the assay reagents , comprising:providing the code from the encoded container to a website;decoding the code to identify the encoded container through the website;providing instructions to the assay driver which includes a microprocessor which executes the instructions on the assay driver to initiate and complete the assay; andadding the sample and/or the control to the encoded container2. The method of further including determining intensity of color claim 1 , fluorescence or chemiluminescence from the encoded container to determine the assay ...

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Номер записи: 4
26-04-2018 дата публикации

Assay Wells with Hydrogel as a Well-Contents Separator and a Pigment-Based Temperature Indicator

Номер: US20180111128A1
Автор: Atul Varadhachary, Brad Ernest Munoz, Dev Chatterjee, Leo LlNBECK, III, Michael John Heffernan
Принадлежит: Fannin Innovation Studio Inc, Fannin Partners LLC

In a polymer assay cartridge having wells containing reagents, beads and sample, where the wells are covered (e.g., with Parafilm® or films) and shipped to the point of care, the reagents and well contents can leak out. The reagent solutions are made semi-solid by adding hydrogel reagents and cooling to form a gel. Preferably, the hydrogel is heated before an assay is conducted with the cartridge, and pigmented beads in the wells indicate melting or excessive heating, or congealing of the hydrogel, based on pigment color change

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Номер записи: 5
26-04-2018 дата публикации

Automated Driving of an Assay

Номер: US20180113126A1
Автор: Chatterjee Dev, Heffernan Michael John, III Leo, LlNBECK, Varadhachary Atul
Принадлежит:

The invention herein relates to conducting assays with an apparatus including a substantially transparent assay cartridge loaded with magnetic beads, and a magnet carrier base positioned below a scanning platform holding the assay cartridge. The assay cartridge includes magnetic beads, sample and control solutions in some wells, and assay reagents in others. A microcomputer controls a stepping motor which controls movement of the magnet carrier base, and causes the magnetic beads to travel from one well to another. An electromagnetic coil-spring assembly induces mixing of well contents with the magnetic beads on actuation. The assay cartridge is authenticated by sending its encoded identifier to a server or website, and assay instructions are provided remotely to the microcomputer. Following assay completion, the cartridge can have color change or other assay indication detected, and the results sent to the server or website or another recipient. 125-. (canceled)26. An apparatus for performing an assay where magnetic beads are moved through a plurality of wells which contain assay reagents , comprising:a substantially planar assay cartridge having a plurality of wells which are indentations in a first substantially planar surface of said cartridge, and said wells are separated and are connected by channels running between wells; andat least one scanning magnet positioned to attract one or more sets of magnetic beads in the wells and move them with movement of the scanning magnet, anda motor moves the at least one scanning magnet with respect to the assay cartridge along a first axis and a coil is actuated and de-actuated to oscillate said at least one scanning magnet along a second axis, wherein said first axis intersects the second axis.27. The apparatus of claim 26 , wherein the at least one scanning magnet is held in a magnet holder which is held by a base claim 26 , and wherein the magnet holder is moveable with respect to the base along the second axis.28. The ...

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Номер записи: 6
17-12-2020 дата публикации

Assay Device with Chambers Separated by Air Gaps

Номер: US20200393453A1
Автор: Dev Chatterjee, Leo Linbeck, Iii, Michael John Heffernan
Принадлежит: Fannin Partners LLC

In a polymer assay cartridge having wells containing reagents, beads and sample, where the wells are covered (e.g., with Parafilm® or films) and shipped to the point of care, the reagents and well contents can leak out. The reagent solutions are made semi-solid by adding hydrogel reagents and cooling to form a gel. Preferably, the hydrogel is heated before an assay is conducted with the cartridge, and pigmented beads in the wells indicate melting or excessive heating, or congealing of the hydrogel, based on pigment color change

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Номер записи: 7
08-01-2009 дата публикации

Novel strategies for delivery of active agents using micelles and particles

Номер: US20090011993A1
Автор: Bali Pulendran, Jihua Hao, Marcin Kwissa, Michael Davis, Michael John Heffernan, Niren Murthy, Robert H. Pierce, Stephen C. Yang
Принадлежит: EMORY UNIVERSITY, Georgia Tech Research Corp, UNIVERSITY OF ROCHESTER

The present invention provides biodegradable particles (e.g., three-dimensional particles) and micelles which can be used to encapsulate active agents for delivering to a subject. The present invention further provides methods for producing and delivering such particles and micelles. Additionally, the invention provides vaccination strategies that encompass the use of the novel particles and micelles.

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Номер записи: 8
28-08-2012 дата публикации

Strategies for delivery of active agents using micelles and particles

Номер: US8252846B2
Автор: Bali Pulendran, Jihua Hao, Marcin Kwissa, Michael Davis, Michael John Heffernan, Niren Murthy, Robert H. Pierce, Stephen C. Yang
Принадлежит: EMORY UNIVERSITY, Georgia Tech Research Corp, UNIVERSITY OF ROCHESTER

The present invention provides biodegradable particles (e.g., three-dimensional particles) and micelles which can be used to encapsulate active agents for delivering to a subject. The present invention further provides methods for producing and delivering such particles and micelles. Additionally, the invention provides vaccination strategies that encompass the use of the novel particles and micelles.

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Номер записи: 9
24-10-2020 дата публикации

Automated remotely instructed driving of an assay

Номер: CA3041227A1
Автор: Atul Varadhachary, Dev Chatterjee, Leo Linbeck, Iii, Michael John Heffernan
Принадлежит: Fannin Partners LLC

The invention relates to conducting assays with an apparatus including a substantially transparent assay cartridge loaded with magnetic beads, and a magnet carrier base positioned below a scanning platform holding the assay cartridge. A microcomputer controls a stepping motor which controls movement of the magnet carrier base, and causes the magnetic beads to travel from one well to another, where the wells contain different assay reagents. An electromagnetic coil-spring assembly induces mixing of well contents with the magnetic beads on actuation. The assay cartridge is authenticated by sending its encoded identifier to a server or website, and assay instructions are provided remotely to the microcomputer. Following assay completion, the cartridge can have color change or other assay indication detected, and the results sent to the server or website or another recipient. Concurrently assaying a control allows modification of assay results based on measured field conditions.

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Номер записи: 10
23-06-2022 дата публикации

Device for the management of incontinence-related symptoms

Номер: US20220192810A1
Автор: Amanda Gibbens, Carine Rizk, Christine Luk, Deepti Gopinath, Leo Linbeck, Iii, Michael John Heffernan
Принадлежит: Fannin Partners LLC

The present invention relates to the application of medical devices that manage urinary incontinence. The inter-bladder/urethra implanted device allows for passive urine leakage above a threshold bladder pressure and subject-controlled opening and closing of a valve to allow urine passage, below the threshold bladder pressure. The valve is preferably a deformable sac which seals against the interior of the urethra when closed. The valve can be opened by withdrawing slightly from the urethra surface. Passive urine leakage to prevent over-pressure can be facilitated by including external channels on the valve sac. In another embodiment, the valve sac has a central passage which expands and contracts for opening and closing, respectively.

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Номер записи: 11