09-02-2012 дата публикации
Номер: US20120035194A1
The present invention relates to compounds of formula (I), 5. (canceled)6. The compound according to claim 1 , wherein Ris H claim 1 , halo claim 1 , hydroxy claim 1 , (C-C)alkoxy claim 1 , (C-C)alkyl claim 1 , —(C═O)—R claim 1 , —(C═O)—NRR claim 1 , —(CRR)(3-10)-membered cycloalkyl claim 1 , —(CRR)(C-Caryl) claim 1 , —(CRR)(4-10)-membered heterocyclyl claim 1 , —(CRR)(CRR)(3-10)-membered cycloalkyl claim 1 , —(CRR)O(CRR)(C-C)aryl claim 1 , or —(CRR)O(CRR)(4-10)-membered heterocyclyl.7. The compound according to claim 1 , wherein Ris (C-C)alkyl claim 1 , —(CRR)(3-10)-membered cycloalkyl claim 1 , —(CRR)(C-Caryl) claim 1 , or —(CRR)(4-10)-membered heterocyclyl.8. The compound according to claim 1 , wherein any carbon atoms of the (C-C)alkyl claim 1 , the (3-10)-membered cycloalkyl claim 1 , the (C-C)aryl and the (4-10)-membered heterocyclyl moieties of the foregoing R claim 1 , R claim 1 , R claim 1 , R claim 1 , Rand Rare optionally substituted with 1 to 3 Rsubstituents each independently selected from halo claim 1 , cyano claim 1 , hydroxy claim 1 , (C-C)alkoxy claim 1 , (C-C)alkyl claim 1 , —(C═O)—R claim 1 , —NR(C═O)—R claim 1 , —(C═O)—NRR claim 1 , —(C═O)—NRR claim 1 , —NRR claim 1 , —S(O)R claim 1 , —NR—S(O)—R claim 1 , —NR—S(O)—R claim 1 , —(CRR)(3-10)-membered cycloalkyl claim 1 , —(CRR)(C-Caryl) claim 1 , —(CRR)(4-1 membered heterocyclyl claim 1 , —(CRR)(C═O)(CRR)(3-10)-membered cycloalkyl claim 1 , —(CRR)(C═O)(CRR)(C-C)aryl claim 1 , and —(CRR)(C═O)(CRR)(4-10)-membered heterocyclyl.9. The compound according to claim 1 , wherein any carbon atoms of the (C-C)alkyl claim 1 , the (3-10)-membered cycloalkyl claim 1 , the (C-C)aryl and the (4-10)-membered heterocyclyl moieties of the foregoing Rare optionally substituted with 1 to 3 Rsubstituents each independently selected from halo claim 1 , hydroxy claim 1 , (C-C)alkoxy claim 1 , (C-C)alkyl claim 1 , and —NRR.10. The compound according to claim 1 , wherein any nitrogen atoms of the (4-10)-membered heterocyclyl ...
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