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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Форма поиска

Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 140. Отображено 100.
14-03-2013 дата публикации

Optical Pointing Device, And Electronic Apparatus Provided With Same

Номер: US20130063399A1
Принадлежит: SHARP KABUSHIKI KAISHA

To produce an ultrathin and easily assembled optical pointing device by reducing the number of components, an optical pointing device () of the present invention includes: a light source () for emitting light to an object (); a light guide () for propagating therethrough light scattered by the object (), the light guide including an image forming section () for forming an image with use of the light scattered by the object (); and an image capturing section () for capturing the image with the light that has been scattered by the object () and that has exited the light guide (). The light guide () guides a light beam (L) from the object via no air through an optical path extending from (i) a position where the light beam (L) enters the light guide to (ii) a position where the light beam exits the light guide (). 1. An optical pointing device comprising:a light source for emitting light to an object;a light guide for propagating therethrough light having been scattered by the object, the light guide including an image forming section for forming an image with use of the scattered light; andan image capturing section for capturing the image with use of the scattered light having exited the light guide,the light guide guiding the scattered light via no air through an optical path extending from (i) a position at which the scattered light enters the light guide to (ii) a position at which the scattered light exits the light guide.2. The optical pointing device according to claim 1 ,wherein:the image forming section reflects the scattered light in a direction opposite to a light-guide direction.3. The optical pointing device according to claim 1 , 'the light guide is provided with a reflecting surface on at least one of an upper surface and lower surface of the light guide.', 'wherein4. The optical pointing device according to claim 1 ,wherein: an entrance section through which the scattered light enters the light guide; and', 'an optical path transforming section for ...

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08-01-2015 дата публикации

NOVEL TRIAZINE DERIVATIVE

Номер: US20150011751A1
Принадлежит:

To provide a novel triazine derivative represented by the following formula (I): The present invention relates to a pharmaceutical, and particularly to a novel triazine derivative having a BTK inhibitory effect, or a pharmaceutically acceptable salt thereof.Bruton's tyrosine kinase (BTK) is a member of the Tec family of non-receptor tyrosine kinases, and is an important signaling enzyme which is expressed in all hematopoietic cell types except for T lymphocytes and natural killer cells. BTK is an important control factor associated with survival, differentiation, proliferation and activation of B-cells, and takes an important role in signaling of B-cells (Non Patent Literatures 1 and 2). A B-cell receptor (BCR) of the cell surface signals into cells through BTK existing in the downstream of BCR and, therefore, it is considered that abnormal activation of the signaling pathway of B-cells accelerates proliferation and survival of cancer cells of B-cell lymphoma, chronic lymphocytic leukemia and the like (Non Patent Literature 3). It is known that BTK also plays an important role in the signal pathway of a large number of other cells, and it is said that BTK is involved in allergic diseases, self-immune diseases, inflammatory diseases and the like (Non Patent Literature 1). For example, it is known that BTK plays an important role for signaling of a high affinity IgE receptor (FcεRI) in mast cells, and degranulation decreases and the production of proinflammatory cytokines decreases in BTK-deficient mast cells (Non Patent Literature 4). It is suggested that BTK is involved in systemic lupus erythematosus (SLE) in a test of a BTK-deficient mouse (Non Patent Literature 5). Furthermore, the BTK mutant mouse exhibits resistance to the onset of collagen-induced arthritis (Non Patent Literature 6). Therefore, the compound having a BTK inhibitory activity is useful for the treatment of diseases which are involved in BTK signaling, for example, cancer, B-cell lymphoma, and ...

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10-02-2022 дата публикации

DENTAL GLASS POWDER AND DENTAL COMPOSITION

Номер: US20220040048A1
Принадлежит:

A dental glass powder includes 15 to 40% by mass of zinc oxide (ZnO), 20 to 55% by mass of silicon oxide (SiO), 6 to 20% by mass of aluminum oxide (AlO), 1 to 13% by mass of calcium oxide (CaO), and 1 to 19% by mass of fluorine (F). 1. A dental glass powder comprising:15 to 40% by mass of zinc oxide (ZnO);{'sub': '2', '20 to 55% by mass of silicon oxide (SiO);'}{'sub': 2', '3, '6 to 20% by mass of aluminum oxide (AlO);'}1 to 13% by mass of calcium oxide (CaO), and 1 to 19% by mass of fluorine (F).2. The dental glass powder according to claim 1 , further comprising more than 0% by mass and 15% by mass or less of boron oxide (BO).3. The dental glass powder according to claim 1 , further comprising more than 0% by mass and 10% by mass or less of phosphorus(V) oxide (PO).4. The dental glass powder according to claim 1 , further comprising more than 0% by mass and 10% by mass or less of sodium oxide (NaO).5. The dental glass powder according to claim 1 , wherein the dental glass powder is used for a dental composition.6. A dental composition containing a glass powder claim 1 , the glass powder comprising:15 to 40% by mass of zinc oxide (ZnO);{'sub': '2', '20 to 55% by mass of silicon oxide (SiO);'}{'sub': 2', '3, '6 to 20% by mass of aluminum oxide (AlO);'}1 to 13% by mass of calcium oxide (CaO), and1 to 19% by mass of fluorine (F). The present application is based on and claims priority to Japanese patent application No. 2020-132351 filed on Aug. 4, 2020, with the Japanese Patent Office, the entire contents of which are hereby incorporated by reference.The disclosures herein relate to dental glass powders and dental compositions.As a dental glass powder, aluminosilicate glass powders are well known. Among aluminosilicate glass powders, a fluoroaluminosilicate glass powder is widely used because the fluoroaluminosilicate glass powder is expected to exhibit the inhibition of dental decalcification (for example, see Patent Documents 1 and 2).Conventionally, a ...

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31-01-2019 дата публикации

DENTAL INVESTMENT

Номер: US20190029785A1
Принадлежит:

Provided is a dental investment that is a dental phosphate-bonded investment including boron nitride at 0.1% to 5% by weight. 1. A dental investment that is a dental phosphate-bonded investment including boron nitride at 0.1% to 5% by weight. The present invention relates to a dental investment.When a part of a tooth is removed or lost by a dental treatment or the like, as it is impossible for the tooth to naturally regrow the removed portion or the lost portion, a dental prosthesis is provided at the removed portion or the lost portion. As a material of a dental prosthesis, conventionally, metal is used. However, from a viewpoint of avoiding metal material due to metal allergy, or from an aesthetic viewpoint, a demand for a dental prosthesis made of ceramic material is increasing in recent years.Among ceramics materials, lithium silicate-based glass ceramics having high strength and an aesthetic property are widely used as materials for dental prostheses in recent years. Methods of molding lithium silicate-based glass ceramics into dental prosthesis are roughly divided into two categories. One category is a mechanical processing method in which a cutting process and the like are performed on block-shaped glass ceramics by a processing machine, and the other category is a press molding method in which a molding process is performed by applying high pressure to glass ceramics in a mold.In the press molding method, a wax pattern having a shape of a dental prosthesis is produced, and the wax pattern is embedded into the dental investment. After the dental investment hardens, the wax pattern is burned. Thereby, a mold having a cavity of the shape of the dental prosthesis is obtained.Next, using a heating/pressing molding machine for dental ceramics, ingot state glass ceramics is heated to a temperature lower by about 30° C. to 50° C. than the melting point of the glass ceramics to be in a softened state. Then, the glass ceramics is pushed into the cavity of the mold to ...

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15-03-2018 дата публикации

MOUNTING PEDESTAL, LIGHT-EMITTING DEVICE, MOVING-BODY LIGHTING DEVICE, AND MOVING BODY

Номер: US20180073718A1
Принадлежит:

A mounting pedestal is disposed on a wheeled vehicle and a light emitter is mounted on the mounting pedestal. The mounting pedestal includes a metal layer and an insulating layer stacked on the metal layer. The insulating layer has a major surface facing in a direction of travel of the wheeled vehicle and a heat escape port in which solder that joins the light emitter and the metal layer is disposed. The mounting pedestal has a step which arranges the major surface into a plurality of major surfaces. 1. A mounting pedestal disposed on a moving body and on which a light emitter is mounted , the mounting pedestal comprising:a metal layer; andan insulating layer stacked on the metal layer,wherein the insulating layer has a major surface facing in a direction of travel of the moving body and a heat escape port in which a joining component that joins the light emitter and the metal layer is disposed, andthe mounting pedestal has a step which arranges the major surface into a plurality of major surfaces.2. A mounting pedestal on which light emitters may be mounted , comprising:a metal layer; andan insulating layer stacked on the metal layer,wherein the metal layer and insulating layer are arranged in a stepped structure which includes a plurality of steps each having a major surface,the major surface of each of the plurality of steps is configured to receive and provide power to a corresponding light emitter, andthe insulating layer on each of the plurality of steps includes a heat escape port in which a joining component that joins the light emitter and the metal layer can be disposed.3. The mounting pedestal according to claim 1 , further comprisingan electrical line disposed on a side of the light emitter opposite a light emitting side of the light emitter and having a power supply surface that supplies power to the light emitter,wherein the power supply surface is offset from the heat escape port in an approximately vertical direction.4. The mounting pedestal ...

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14-03-2019 дата публикации

WAX PATTERN SURFACE-TREATING AGENT

Номер: US20190076223A1
Принадлежит:

A wax pattern surface-treating agent includes a solvent, boron nitride, and at least one surfactant selected from a group consisting of an anionic surfactant, a cationic surfactant, a non-ionic surfactant, and an amphoteric surfactant. 1. A wax pattern surface-treating agent comprising:a solvent;boron nitride; andat least one surfactant selected from a group consisting of an anionic surfactant, a cationic surfactant, a non-ionic surfactant, and an amphoteric surfactant.2. The wax pattern surface-treating agent according to claim 1 , whereina content ratio of the boron nitride is greater than or equal to 0.02% by mass and less than or equal to 20% by mass; anda content ratio of the at least one surfactant is greater than or equal to 0.01% by mass and less than or equal to 8% by mass.3. The wax pattern surface-treating agent according to claim 1 , whereinthe solvent includes at least one substance selected from a group consisting of water, ethanol, methanol, propanol, butanol, pentanol, acetone, tetrahydrofuran, and methyl ethyl ketone. The present invention relates to a wax pattern surface-treating agent.When a portion of a tooth is removed or lost through a dental procedure or the like, because the removed portion or lost portion cannot be restored naturally, a dental prosthesis is arranged in the removed portion or lost portion. Metal has conventionally been used as the material for a dental prosthesis. However, from the viewpoint of aesthetics, dental prostheses made of ceramics are increasingly being used in recent years.A dental prosthesis made of ceramics may be formed, for example, by first investing a wax pattern that is molded into a shape corresponding to the dental prosthesis to be formed in investment material and burning out the wax pattern after the investment material has set to form a mold. Then, by heating a ceramic block and press molding the ceramic block into the above mold, a ceramic dental prosthesis having a desired shape may be fabricated.For ...

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16-06-2016 дата публикации

NOVEL TRIAZINE DERIVATIVE

Номер: US20160168122A1
Принадлежит:

The purpose of the present invention is to provide a novel triazine derivative of the formula (I): 3. The triazine derivative according to claim 1 , wherein{'sup': '1', 'claim-text': 'or a pharmaceutically acceptable salt thereof.', 'Ris a hydroxymethyl group,'}4. The triazine derivative according to claim 1 , wherein Ris a substituted or unsubstituted cycloalkyl group claim 1 ,or a pharmaceutically acceptable salt thereof.5. The triazine derivative according to claim 4 , wherein Ris a cyclopropyl group claim 4 ,or a pharmaceutically acceptable salt thereof.6. The triazine derivative according to claim 1 , wherein Ris a methyl group claim 1 ,or a pharmaceutically acceptable salt thereof.7. The triazine derivative according to claim 1 , wherein Ris a hydrogen atom claim 1 ,or a pharmaceutically acceptable salt thereof.8. The triazine derivative according to claim 1 , wherein A is a nitrogen atom claim 1 ,or a pharmaceutically acceptable salt thereof.9. The triazine derivative according to claim 1 , wherein A is C—R claim 1 ,or a pharmaceutically acceptable salt thereof.12. A pharmaceutical composition comprising the triazine derivative according to claim 1 , or a pharmaceutically acceptable salt thereof.13. A method of inhibiting a Bruton's tyrosine kinase activity in a cell claim 1 , comprising administering to the cell the triazine derivative according to claim 1 , or a pharmaceutically acceptable salt thereof.14. A method of treating a disease related to an abnormal cell response through a Bruton's tyrosine kinase in a subject in need thereof claim 12 , comprising administering to the subject the pharmaceutical composition of .15. The method of claim 14 , wherein the disease is selected from the group consisting of self-immune diseases claim 14 , inflammatory diseases claim 14 , bone diseases claim 14 , cancer claim 14 , lymphoma claim 14 , and arthritis.16. A pharmaceutical composition comprising the compound according to claim 10 , or a pharmaceutically ...

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08-07-2021 дата публикации

SCALE

Номер: US20210206023A1
Принадлежит: GC Corporation

To provide a scale which makes it possible to adjust the temperature of a furnace so that a ceramic blank can be properly heated even if various conditions such as the combination of the used ceramic blank and investment, and the type and size of the furnace vary, the scale comprises: a scale part; and a base part, the scale part and the base part being formed of wax or resin, wherein the base part has a shape of protruding from part of the scale part, a size of the scale part is larger than that of the base part in a direction orthogonal to a protruding direction of the base part. 1. A scale that is for adjusting temperature of a furnace that heats a ceramic blank used in press molding of a dental prosthesis , the scale comprising:a scale part; and a base part, the scale part and the base part being formed of wax or resin, whereinthe base part has a shape of protruding from part of the scale part, a size of the scale part is larger than that of the base part in a direction orthogonal to a protruding direction of the base part.2. The scale according to claim 1 , wherein the scale part has a shape of a grid. The present invention relates to scales used when dental prostheses are made by pressing.If a tooth is partially removed or lost by dental treatment or the like, a dental prosthesis is arranged on a cavity due to this removal or loss because the tooth does not naturally recover from the removal or loss. While metal is conventionally used as material for a dental prosthesis, ceramic dental prostheses have been increasingly used in recent years in view of aesthetics.For example, a ceramic dental prosthesis is made according to the following procedures:first, a wax pattern that is shaped so as to correspond to the shape of a dental prosthesis to be formed is secured to a crucible former (wax model upright holder for making a mold of a dental prosthesis) via a sprue line that is shaped so as to correspond to a sprue line portion described later, to be invested in ...

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04-08-2016 дата публикации

NOVEL TRIAZINE DERIVATIVE

Номер: US20160221991A1
Принадлежит:

To provide a novel triazine derivative represented by the following formula (I): 2. The triazine derivative according to claim 1 , wherein Q is structure (a) claim 1 , or a pharmaceutically acceptable salt thereof.3. The triazine derivative according to claim 2 , wherein Y is a carbon atom claim 2 , or a pharmaceutically acceptable salt thereof.4. The triazine derivative according to claim 1 , wherein one of Zand Zis a carbon atom and the other is a nitrogen atom claim 1 , or a pharmaceutically acceptable salt thereof.5. The triazine derivative according to claim 1 , wherein Ris a substituted lower alkyl group claim 1 , or a pharmaceutically acceptable salt thereof.6. The triazine derivative according to claim 5 , wherein Ris a lower alkyl group substituted with —OH claim 5 , or a pharmaceutically acceptable salt thereof.7. The triazine derivative according to claim 1 , wherein Ris an unsubstituted cycloalkyl group claim 1 , or a pharmaceutically acceptable salt thereof.8. The triazine derivative according to claim 7 , wherein Ris a cyclopropyl group claim 7 , or a pharmaceutically acceptable salt thereof.9. The triazine derivative according to claim 1 , wherein Ris a halogen atom claim 1 , or a pharmaceutically acceptable salt thereof.10. The triazine derivative according to claim 1 , wherein Ar is a substituted or unsubstituted heteroaryl group claim 1 , or a pharmaceutically acceptable salt thereof.11. The triazine derivative according to claim 10 , wherein Ar is a substituted pyrazolyl group claim 10 , or a substituted pyrrolyl group claim 10 , or a pharmaceutically acceptable salt thereof.13. A pharmaceutical composition comprising the triazine derivative or the pharmaceutically acceptable salt thereof according to .14. A pharmaceutical composition comprising the triazine derivative or the pharmaceutically acceptable salt thereof according to .15. A method of inhibiting a Bruton's tyrosine kinase activity in a cell comprising administering to the cell the ...

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20-08-2020 дата публикации

MOUNTING STRUCTURE FOR OPTICAL MODULE

Номер: US20200266604A1
Принадлежит:

A mounting structure for an optical module includes a light emitting element, a submount board on which the light emitting element is mounted, a main board on which the submount board is mounted, a light guide member provided on the main board, and a diffraction grating optical coupler provided on the main board and connected to the light guide member. The submount board and the main board are bonded to each other on a surface of the submount board different from a surface on which the light emitting element is mounted. 1. A mounting structure for an optical module , the mounting structure comprising:a light emitting element;a submount board on which the light emitting element is mounted;a main board on which the submount board is mounted;a light guide member provided on the main board; anda diffraction grating optical coupler provided on the main board and connected to the light guide member,wherein the submount board and the main board are bonded to each other on a surface of the submount board different from a surface on which the light emitting element is mounted.2. The mounting structure for an optical module of claim 1 ,wherein the diffraction grating optical coupler is irradiated with light from the light emitting element.3. The mounting structure for an optical module of claim 1 ,wherein the submount board is made of silicon.4. The mounting structure for an optical module of claim 3 ,wherein the silicon is processed in a predetermined crystal orientation.5. The mounting structure for an optical module of claim 1 ,wherein an angle formed between a surface of the main board on which the diffraction grating optical coupler is mounted and the surface of the submount board on which the light emitting element is mounted is 54.75°±5°.6. A mounting structure for an optical module of claim 1 ,wherein a spacer is located at a bonding portion between the main board and the submount board.7. The mounting structure for an optical module of claim 6 ,wherein a distance ...

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27-12-2018 дата публикации

MOUNTING PEDESTAL, COMPONENT MOUNTING MODULE, AND MOVING BODY

Номер: US20180370421A1

A mounting pedestal on which a heat generating component is disposed is provided. The mounting pedestal includes a substrate which includes a plurality of bending portions at which the substrate is bent in a staircase shape. An insulating layer is disposed on a surface of the substrate. An interconnecting line is disposed on the insulating layer. In the mounting pedestal, the interconnecting line extends across the plurality of bending portions. In each of the plurality of bending portions, a corner radius (R) of a mountain portion is greater than a corner R of a valley portion. 1. A mounting pedestal on which a heat generating component is disposed , the mounting pedestal comprising:a substrate which includes a plurality of bending portions at which the substrate is bent in a staircase shape;an insulating layer disposed on a surface of the substrate; andan interconnecting line disposed on the insulating layer, whereinthe interconnecting line extends across the plurality of bending portions, andin each of the plurality of bending portions, a corner radius (R) of a mountain portion is greater than a corner R of a valley portion,2. The mounting pedestal according to claim 1 , whereinthe substrate includes a first planar portion on which the heat generating component is disposed, and a second planar portion located adjacent to the first planar portion across one of the plurality of bending portions,the first planar portion comprises a plurality of first planar portions and the second planar portion comprises a plurality of second planar portions, andthe substrate is bent in the staircase shape in which the plurality of first planar portions and the plurality of second planar portions are alternately arranged.3. The mounting pedestal according to claim 2 , whereinthe plurality of first planar portions are arranged radially.4. The mounting pedestal according to claim 2 , whereinthe interconnecting line includes a first line portion on each of the plurality of first ...

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24-02-2006 дата публикации

2, 4-pyrimidinediamines useful in the treatment of neoplastic diseases, inflammatory and immune system disorders

Номер: CA2533320A1
Принадлежит: Individual

Novel pyrimidine derivatives of formula (I) Wherein R is selected from C16-1 0 aryl, C5-10heteroaryl, C3-12cycloalkyl and C3-10heterocycloalkyl; R0-R6 as described herein; and their use for the manufacture of a medicament for the treatment or prevention of a disease wich responds to inhibition of FAK and/ or ALK and/or ZAP-70 and/or IGF-IR.

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05-12-2018 дата публикации

Dental investment material

Номер: EP3409261A1
Принадлежит: GC Corp, GC Dental Industiral Corp

Provided is a dental investment that is a dental phosphate-bonded investment including boron nitride at 0.1% to 5% by weight.

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28-09-1999 дата публикации

Optical pickup device

Номер: JPH11265515A
Принадлежит: Sharp Corp

(57)【要約】 【課題】 回折素子を利用した光ピックアップ装置にお いて回折素子の各分割領域間の回折効率差をなくし、ト ラッキング誤差信号にオフセットを発生させることがな く、正確なトラッキング制御を行う。 【解決手段】 光源と、光源からの光を記録媒体上に集 光させるとともに記録媒体上からの戻り光を回折素子に 導く光学系と、上記戻り光を受光素子側に回折させる回 折素子と、回折素子で回折された戻り光に基づいて少な くともフォーカス誤差及びトラッキング誤差の検出を行 う受光素子とを備えた光ピックアップ装置において、上 記回折素子2の最も受光素子7から遠い領域と、回折素 子2の最も受光素子7から近い領域の格子ピッチが略同 じであって、かつ受光素子2は上記光源の光軸方向にお いて光源と上記回折素子7の間に配置することを特徴と する光ピックアップ装置。

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14-12-1991 дата публикации

Polarization diffraction element and polarization detector employing the same

Номер: CA2043978A1
Принадлежит: Sharp Corp

A polarization diffraction element comprising two diffraction gratings formed on both faces of a substrate respectively. Both the diffraction gratings have grating lines which are arranged at the same grating pitch, and whose directions mutually form a predetermined minute angle. The grating lines may also be arranged parallel to each other. In this case, the relationship between grating pitches D1, D2 of the respective diffraction gratings and the wavelength .lambda. of an incident light is expressed as: 0 < ¦ .lambda.(1/D1 - 1/D2)(1 - (.lambda./2D1)2) - (1/2) ¦ ~ 0.35; or 0 < ¦ .lambda.(1/D1 - 1/D2)(1 - (.lambda./D1 - .lambda./2D2)2) - (1/2) ¦ ~ 0.35 In a polarization detector employing this polarization diffraction element, a single converging lens of a small effective diameter separates one polarization from another polarization and converges them separately on different photodetectors. Consequently, a still more compact and lightweight optical pickup can be manufactured.

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14-04-2016 дата публикации

Novel triazine derivative

Номер: AU2014322239A1
Принадлежит: Carna Biosciences Inc

[Problem] To provide a novel triazine derivative. [Solution] A triazine derivative or pharmaceutically acceptable salt thereof represented by formula (I). (In the formula: R

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18-05-2022 дата публикации

Diffusion element, projection device, and space recognition device

Номер: JP2022074585A
Принадлежит: Nissei Technology Corp

【課題】高効率で広視野角と小型・薄型化を両立する拡散素子、これを用いた投射装置、空間認識装置及び測距装置を提供すること。【解決手段】光源側に配置され、複数のマイクロレンズが平面視で六方格子状に配列されてなる第一レンズアレイと、第一レンズアレイの光源とは反対側に配置され、複数のマイクロレンズが平面視で六方格子状に配列されてなる第二レンズアレイと、を有し、第一レンズアレイにおける隣接するマイクロレンズの光軸間距離が最短となる方向に対して、第二レンズアレイにおける隣接するマイクロレンズの光軸間距離が最短となる方向が直交する方向に第一及び第二レンズアレイがそれぞれ配置され、第一及び第二レンズアレイの各々マイクロレンズの直径をP、マイクロレンズの深さをDとしたときに、0.3<D/P<0.65である。【選択図】図1

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17-05-2016 дата публикации

optical indicating device, and electronic apparatus provided therewith.

Номер: BR112012016214A2
Принадлежит: Sharp Kk

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16-11-1991 дата публикации

Optical head

Номер: CA2041928A1

An optical head comprising a diffracting element having two tracking diffracting regions separated by a division line extending in a direction corresponding to a track direction of a recording medium, and one focusing diffracting region separated from the tracking diffracting regions by a division line extending in a direction corresponding to a radial direction of the recording medium. The optical head further comprises a light receiving element having two tracking light receiving regions for receiving diffracted lights produced in the tracking diffracting regions, and two adjoining focusing light receiving regions for receiving a diffracted light produced in the focusing diffracting region. The diffracted light produced in the focusing diffracting region always has a substantially constant light intensity, even when a tracking error occurs. As a result, an offset can be prevented from occurring in a focus error signal by finely adjusting the diffracting element.

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25-04-1995 дата публикации

Optical pickup apparatus

Номер: US5410529A
Принадлежит: Sharp Corp

An optical pickup apparatus for reading out information from an optical disk. The optical pickup includes a light source; and an optical device having a grating pattern for splitting a light beam from said the source into a zero-order diffracted beam and plus and minus first-order diffracted beams. The grating pattern has the center portion and one or more side portions. The efficiency of the center portion for the zero-order diffracted beam is greater than the efficiency of the side portions for the zero-order diffracted beam.

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18-06-1996 дата публикации

Optical pickup

Номер: CA2138436C
Принадлежит: Sharp Corp

The optical pickup of the invention includes a hologram mirror for directing an optical axis of a light beam emitted from a light source to be perpendic-ular to the recording face of a recording medium. The hologram mirror includes: a light transmissive sub-strate having a first surface and a second surface which are opposite to each other, the light beam from the light source entering the substrate from the first surface; a transmissive holographic element, formed on the first substrate, for diffracting the light beam incident thereon to generate a plurality of diffracted beams; and a reflective film, formed on the second sur-face of the substrate, for reflecting the diffracted beams, wherein the holographic element includes a blazed grating which is designed to make a predeter-mined one of the diffracted beams most intense.

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10-02-2016 дата публикации

2,4-Pyrimidinodiamine Useful in the Treatment of Neoplastic Diseases, Inflammatory Disorders and Disorders of the Immune System

Номер: CY1112571T1
Принадлежит: NOVARTIS AG

Νέα πυριμιδινικά παράγωγα του τύπου (Ι) όπου R επιλέγεται από C6-10 αρύλιο, C5-10 ετεροαρύλιο, C3-12 κυκλοαλκύλιο και C3-10 ετεροκυκλοαλκύλιο R0-R6 όπως περιγράφεται στο παρόν και η χρήση τους για την παραγωγή ενός φαρμάκου για την αντιμετώπιση ή πρόληψη μιας νόσου η οποία αποκρίνεται σε αναστολή των FΑΚ και/ή ΑLΚ και/ή ΖΑΡ-70 και/ή ΙGF-ΙR. New pyrimidine derivatives of formula (I) wherein R is selected from C6-10 aryl, C5-10 heteroaryl, C3-12 cycloalkyl and C3-10 heterocycloalkyl R0-R6 as described herein and their use in the manufacture of a medicament for the treatment. or prevention of a disease that responds to inhibition of FAK and / or ALK and / or ZAP-70 and / or IGF-IR.

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29-07-1993 дата публикации

An optical information recording and reproducing device

Номер: CA2088188A1

An optical information recording and reproducing device is provided. The device includes a light source for emitting a light beam, a first diffraction element for splitting the light beam into at least three diffracted beams, an optical system guiding the diffracted beams to a recording medium, and a second diffraction element including at least one division line and a diffraction surface from which the diffracted beams are diffracted. The diffraction surface is divided into at least two regions by the division line or lines. One of the division lines is at a predetermined angle against the direction of a track on the recording medium, and the regions split each of the diffracted beams into at least two parts to diffract the parts in different directions. The device also includes an optical detecting element for detecting the light beams diffracted with the second diffraction element.

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25-06-1995 дата публикации

Optical Pickup

Номер: CA2138436A1

The optical pickup of the invention includes a hologram mirror for directing an optical axis of a light beam emitted from a light source to be perpendic-ular to the recording face of a recording medium. The hologram mirror includes: a light transmissive sub-strate having a first surface and a second surface which are opposite to each other, the light beam from the light source entering the substrate from the first surface; a transmissive holographic element, formed on the first substrate, for diffracting the light beam incident thereon to generate a plurality of diffracted beams; and a reflective film, formed on the second sur-face of the substrate, for reflecting the diffracted beams, wherein the holographic element includes a blazed grating which is designed to make a predeter-mined one of the diffracted beams most intense.

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23-04-1997 дата публикации

A display apparatus

Номер: EP0550155B1
Принадлежит: Sharp Corp

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10-09-2004 дата публикации

Spiro-substituted pyrrolopyrimidines

Номер: CA2517035A1
Принадлежит: Individual

The invention provides compounds of formula (I) or a pharmaceutically acceptable salt or ester thereof formula (I) wherein the symbols have the meaning as defined in the description. Said compounds are inhibitors of cathepsin K and/or cathepsin S and are useful for the treatment of diseases and medical conditions in which cathepsin K and/or cathepsin S is implicated, e.g. various disorders including neuropathic pain, inflammation, rheumatoid arthritis, osteoarthritis, osteoporosis, multiple sclerosis and tumours.

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27-07-2021 дата публикации

pyrimidine derivatives, their use, and pharmaceutical composition and combination

Номер: BR122019010008B8
Принадлежит: NOVARTIS AG

a presente invenção se refere a novos derivados de pirimidina de fórmula i (i), a processos para sua produção, a seu uso como produtos farmacêuticos e a composições farmacêuticas que compreendem esses derivados. the present invention relates to new pyrimidine derivatives of formula I (i), processes for their production, their use as pharmaceuticals and pharmaceutical compositions comprising these derivatives.

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16-05-2019 дата публикации

Dental investment material

Номер: AU2017212882B2
Принадлежит: GC Corp, GC Dental Industiral Corp

Provided is a dental investment material which is a dental phosphate-based investment material containing 0.1-5 wt% of boron nitride.

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31-01-2009 дата публикации

2,4-di(phenylamino) pyrimidines useful in the treatment of neoplastic diseases, inflammatory diseases and immune system disorders

Номер: NZ542219A
Принадлежит: NOVARTIS AG

Disclosed is a compound of formula I wherein the substituents are disclosed within the specification or a pharmaceutically acceptable salt thereof. Also disclosed is the use of the above compound for the manufacture of a medicament for the treatment or prevention of neoplastic diseases and immune system disorders.

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02-03-2006 дата публикации

Pyrimidine derivatives

Номер: CA2577251A1
Принадлежит: Individual

Novel pyrimidine derivatives of formula (I) to processes for their production, their use as pharmaceuticals and to pharmaceutical compositions comprising them.

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18-01-1994 дата публикации

Manufacturing method of optical diffraction grating element with serrated gratings having uniformly etched grooves

Номер: US5279924A
Принадлежит: Sharp Corp

The method of manufacturing an optical diffraction grating element of the present invention is characterized in adopting an ion beam made from a gas chemically reacting with a glass substrate when forming a diffraction grating having a serrated profile upon the glass substrate through an ion beam etching method. Also, when manufacturing an optical diffraction grating element that is divided into a plurality of regions whereon diffraction gratings having different diffraction angles with respect to an incident light are provided, the method of the present invention is characterized in forming slits into a resist film disposed upon a transparent substrate such as a glass substrate, in accordance with the patterns of the diffraction gratings, such that the width of the slits is constant irrespectively of the regions. Accordingly, the method of manufacturing an optical diffraction grating element of the present invention enables to improve the diffraction efficiency of the optical diffraction grating element, and to enhance the optical efficiency of an optical head device. The SN ratio of the output signals released by the optical head device may be thus improved and the servo error control executed accurately.

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19-07-2012 дата публикации

1,2-disubstituted-4-benzylamino-pyrrolidine derivatives as CETP inhibitors useful for the treatment of diseases such as hyperli pidemia or arteriosclerosis

Номер: AU2012203815A1
Принадлежит: NOVARTIS AG

C:NRPonrlDCC\NLB234X5 I DOC-2W6>2fl12 The present invention provides a compound of formula (1): wherein the variants R1, R2, R3, R4, R6, R7 are as defined herein, and wherein said compound is an inhibitor of CETP, and thus can be employed for the treatment of a disorder or disease mediated by CETP or responsive to the inhibition of CETP. R7 (l)

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31-05-2006 дата публикации

2, 4-pyrimidinediamines useful in the treatment of neoplastic diseases, inflammatory and immune system disorders

Номер: EP1660458A1
Принадлежит: IRM LLC, NOVARTIS AG, Novartis Pharma Gmbh

Novel pyrimidine derivatives of formula (I) Wherein R is selected from C16-10 aryl, C5-10heteroaryl, C3-12cycloalkyl and C3-10heterocycloalkyl; R0-R6 as described herein; and their use for the manufacture of a medicament for the treatment or prevention of a disease wich responds to inhibition of FAK and/or ALK and/or ZAP-70 and/or IGF-IR.

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24-08-2017 дата публикации

scale

Номер: JP2017144031A
Принадлежит: GC Corp, GC Dental Industiral Corp

【課題】使用するセラミックスブランクと埋没材との組み合わせ、炉の種類や大きさ等、種々の条件が異なっても、セラミックスブランクを適切に加熱することができる温度に炉の温度を調整することができるスケールを提供する。 【解決手段】歯科用補綴物のプレス成形に用いるセラミックスブランクを加熱する炉の温度を調整するスケール(10)であって、ワックス又は樹脂により形成されたスケール部(11)及び基部(12)を有し、基部はスケール部の一部から突出した形状を有するとともに、当該突出した方向に直交する方向の大きさが、基部よりもスケール部の方が大きく形成されている。 【選択図】図1

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15-03-2018 дата публикации

Mounting base, light emitting device, moving body lighting device and moving body

Номер: DE102017119779A1

Auf einem Radfahrzeug (100) ist ein Befestigungssockel (200) angeordnet und auf dem Befestigungssockel (200) ist ein Lichtemitter (50) angebracht. Der Befestigungssockel (200) umfasst eine Metallschicht (231) und eine auf der Metallschicht (231) gestapelte Isolierschicht (232). Die Isolierschicht (232) weist eine Hauptfläche (250), die in die Fahrtrichtung des Radfahrzeugs (100) gewandt ist, und einen Wärmeaustrittsanschluss (233) auf, in dem das Lötmittel (58), das den Lichtemitter (50) und die Metallschicht (231) zusammenfügt, angeordnet ist. Der Befestigungssockel (200) weist eine Stufe (201) auf, welche die Hauptfläche (250) in mehreren Hauptflächen (250) anordnet. On a wheeled vehicle (100) a mounting base (200) is arranged and on the mounting base (200) a light emitter (50) is mounted. The mounting base (200) comprises a metal layer (231) and an insulating layer (232) stacked on the metal layer (231). The insulating layer (232) has a main surface (250) turned in the direction of travel of the wheeled vehicle (100) and a heat exit port (233) in which the solder (58), the light emitter (50) and the metal layer ( 231) together, is arranged. The mounting base (200) has a step (201) which places the main surface (250) in a plurality of major surfaces (250).

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18-07-1990 дата публикации

An optical pickup apparatus

Номер: EP0378438A2
Принадлежит: Sharp Corp

An optical pickup apparatus comprises a diffraction device (2) in which a laser beam (A) from a light source (1) is diffracted by the diffraction device to produce a main beam (A₃) and two sub-beams (A₁, A₂) which are focused on a recording medium (5). The beams (B) reflected from the recording medium (5) are diffracted by the diffraction device (2) to be directed to at least one photodetector (6), whereby a tracking error signal (TE) can be detected from output signals of the photodetector by the three-spot method that is so highly reliable that an offset never arises in the tracking error signal even when the optical axis of the optical system is displaced from a given position.

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11-06-2009 дата публикации

1,2-disubstituted-4-benzylamino-pyrrolidine derivatives as cetp inhibitors useful for the treatment of diseases such as hyperli pidemia or arteriosclerosis

Номер: CA2707651A1
Принадлежит: Individual

The present invention provides a compound of formula (I): wherein the variants R1, R2, R3, R4, R6, R7 are as defined herein, and wherein said compound is an inhibitor of CETP, and thus can be employed for the treatment of a disorder or disease mediated by CETP or responsive to the inhibition of CETP.

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21-10-1991 дата публикации

Optical pickup device

Номер: CA2040787A1

ABSTRACT OF THE DISCLOSURE An optical pickup device having an optical system provided with at least a light source, a shaping prism, an diffracting element and a photodetector. The light source projects light whose intensity distribution has an elliptical shape in its cross section orthogonal to the optical axis. The shaping prism directs the light to a recording medium after shaping the intensity distribution thereof into a circular shape. The diffracting element has diffraction regions formed by at least one division line substantially parallel to a reference direction. The light reflected from the recording medium forms an elliptical bright portion on the diffracting element. The photodetector is divided by a plurality of division lines, at least one of which is substantially parallel to the reference direction. The diffracting element diffracts the reflected light so as to converge it on the photodetector. Here, a hypothetical line extending from a projecting point of the light source through the center of a light-receiving face of the photodetector is also set to be parallel to the reference direction. For example, when the shaping prism is to shape the intensity distribution having the elliptical shape with respect to its minor axis direction, the optical system is arranged so that the minor axis of the bright portion is parallel to the division line of the diffracting element. Thus, it is possible to always obtain an accurate focusing control signal.

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24-02-1998 дата публикации

Polarization separating synthesizing device provided with polarization selective reflection element and manufacture of cancave shaped polarization selective reflection element

Номер: JPH1054907A
Принадлежит: Sharp Corp

(57)【要約】 【課題】 光の有効利用効率を向上でき、例えば液晶プ ロジェクターに応用する場合には、明るく鮮明な映像を 得ることができる偏光選択性反射素子を備えた偏光分離 合成装置を提供する。 【解決手段】 無偏光の入射光の内、第1の直線偏光を 透過し、かつ該第1の直線偏光と振動面が90度回転し た第2の直線偏光を反射し、或いはある方向の円偏光を 透過し、かつ該円偏光と逆回りの円偏光を反射するよう な偏光選択性反射素子を備えた偏光分離合成装置におい て、偏光選択性反射素子13で第1の凹型偏光反射面を 形成すると共に、第1の凹型偏光反射面で反射された反 射光を再度反射する第2の凹型反射面16を有し、第2 の凹型反射面16で再度反射された反射光15bの光軸 方向が、第1の凹型反射面を透過する透過光15aの光 軸方向と一致するように構成する。

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29-10-1997 дата публикации

Optical element and optical pickup device comprising the same

Номер: EP0803868A2
Принадлежит: Sharp Corp

An optical element comprises a polarization diffraction element that is provided with diffraction gratings that are respectively mounted on different faces of a transparent substrate of a flat plate shape, which grating pitches are equal to each other and approximately equal to the wavelength of an incident light, and which grating lines are parallel; or comprises a phase shifting element or an antireflection element composed by a grating which grating pitch is approximately equal to the wavelength of an incident light, formed on a transparent base; or comprises a polarization diffraction element that is provided with a substrate made of a material having an optical anisotropy property, and a grating, and wherein the thickness of the substrate is set such that the difference that occurs between the phases of the P and S polarizations of a light due to the grating, and the difference that occurs between the phases of the two polarizations when the light propagates through the substrate, and cancel out; or comprises a polarization diffraction unit wherein a diffraction grating which grating pitch is approximately equal to the wavelength of an incident light, is formed on a face of a transparent substrate, and a phase compensating grating which grating lines are substantially orthogonal to the grating lines of the diffraction grating, is formed on the other face of the substrate. An optical pickup device comprises an optical element wherein a grating which grating pitch is approximately equal to the wavelength of an incident light, is formed on a transparent base. An optical pickup device comprises a polarized light detecting unit provided with a diffraction grating which grating pitch is approximately equal to the wavelength of an incident light, that is formed on a transparent substrate, and that splits the incident light into two polarized lights having mutually orthogonal polarizations; a first photodetector that is mounted integrally and virtually in parallel with ...

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04-12-2012 дата публикации

2,4-di(phenylamino) pyrimidines useful in the treatment of neoplastic diseases, inflammatory and immune system disorders

Номер: CA2518932C
Принадлежит: NOVARTIS AG

Novel pyrimidine derivatives of formula (I), to processes for their production, their use as pharmaceuticals in the treatment of neoplastic diseases, inflammatory and immune system disorders and to pharmaceutical compositions comprising them.

Подробнее
29-03-1994 дата публикации

Polarization Detector

Номер: CA2100897A1
Принадлежит: Sharp Corp

A polarization detector of the present invention includes: a polarization diffraction element having a substrate with two facing surfaces which are placed in parallel with each other, a first diffraction grating formed on one surface of the substrate, and a second diffraction grating formed on the other surface of the substrate, light being incident upon the first diffraction grating, each grating pitch of the first diffraction grating and the second diffraction grating being nearly equal to a wavelength of the incident light; a limiting member for limiting an incident region of the incident light with respect to the polarization diffraction element, formed on a light incident side of the first diffraction grating; a converging lens for respectively converging light transmitted through the first diffraction grating and the second diffraction grating and light diffracted by the first diffraction grating and the second diffraction grating into different beam spots; and a pair of photodetectors for detecting each optical intensity of the two beam spots converged by the converging lens.

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05-02-2004 дата публикации

Information processing system, apparatus and method for processing information, and program

Номер: US20040024850A1
Автор: Takahiro Miyake
Принадлежит: Sony Corp

In online shopping or the like via the Internet, a user transmits information indicating a credit card number or the like from a client computer of the user to a server of a mail-order dealer. Before such information is actually transmitted, the client computer displays an object selected depending on the importance level of the information which is going to be transmitted and moves the object from a location close to an information providing agent representative of an agent for the user to a location close to a shop agent representative of an agent for the mail-order dealer. Displaying the object in such a manner makes it possible for the user to recognize that the information is going to be transmitted and recognize the importance level of the information. After completion of moving the object, the client computer actually transmits the information to the server.

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16-02-1999 дата публикации

An optical information recording and reproducing device

Номер: CA2088188C
Принадлежит: Sharp Corp

An optical information recording and reproducing device is provided. The device includes a light source for emitting a light beam, a first diffraction element for splitting the light beam into at least three diffracted beams, an optical system guiding the diffracted beams to a recording medium, and a second diffraction element including at least one division line and a diffraction surface from which the diffracted beams are diffracted. The diffraction surface is divided into at least two regions by the division line or lines. One of the division lines is at a predetermined angle against the direction of a track on the recording medium, and the regions split each of the diffracted beams into at least two parts to diffract the parts in different directions. The device also includes an optical detecting element for detecting the light beams diffracted with the second diffraction element.

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06-07-2004 дата публикации

Optical pickup device

Номер: US6760294B2
Автор: Takahiro Miyake
Принадлежит: Sharp Corp

Light emitted from a semiconductor laser is converted by a collimator lens into a collimated light, which enters into an objective lens of high NA and forms a condensed spot within an optical disk. The light emitted from the semiconductor laser is S-polarized light that oscillates in a direction perpendicular to the plane of incidence.

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28-04-2020 дата публикации

2,4-pyrimidinadiamines, their uses, and pharmaceutical composition

Номер: BRPI0413616B1

"2,4-pirimidinadiaminas úteis no tratamento de doenças neoplásicas, distúrbios inflamatórios e distúrbios do sistema imunológico". novos derivados de pirimidina de fórmula (i) onde r é selecionado de c~ 16-10~ arila, c~ 5-10~ heteroarila, c~ 3-12~ cicloalquila e c~ 3-10~ heterocicloalquila; r^ 0^ - r^ 6^ são como aqui descritos; e seu uso para a produção de um medicamento para o tratamento ou a prevenção de uma doença que responde à inibição de fak e/ou alk e/ou zap-70 e/ou igf-ir. "2,4-pyrimidinadiamines useful in the treatment of neoplastic diseases, inflammatory disorders and disorders of the immune system". new pyrimidine derivatives of formula (i) where r is selected from c ~ 16-10 ~ aryl, c ~ 5-10 ~ heteroaryl, c ~ 3-12 ~ cycloalkyl and c ~ 3-10 ~ heterocycloalkyl; r ^ 0 ^ - r ^ 6 ^ are as described herein; and its use for the production of a medicine for the treatment or prevention of a disease that responds to inhibition of fak and / or alk and / or zap-70 and / or igf-ir.

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16-12-1997 дата публикации

Three-dimensional image display apparatus

Номер: CA2065762C
Принадлежит: Sharp Corp

A three-dimensional image display apparatus which includes a plurality of display devices, a first optical arrangement for synthesizing a plurality of images from the image display devices, a second optical arrangement for changing the position where at least one of the images is projected, the first and second optical arrangements synthesizing a plurality of images formed at different positions.

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19-03-1996 дата публикации

Optical head device

Номер: CA2043387C
Принадлежит: Sharp Corp

An optical head device having an optical system provided with at least a light source, a shaping prism, an diffracting element and a photodetector. The light source emits light whose intensity distribution has an elliptic shape in its cross section orthogonal to the optical axis. The shaping prism directs the light to a recording medium after shaping the intensity distribution thereof into a circular shape. The diffracting element has diffracting regions formed by at least one division line substantially parallel to a reference direction. The light reflected from the recording medium forms an elliptic bright portion on the diffracting element. The photodetector is divided by a plurality of division lines, at least one of which is parallel to the reference direction. When there is no focus error, the diffracting element diffracts the reflected light so as to converge it on the division line substantially parallel to the reference direction in the photodetector. For example, when the shaping prism is adapted to shape the elliptic intensity distribution with respect to its minor axis direction, the optical system is arranged so that the major axis of the bright portion is parallel to the division line of the diffracting element. Thus, it is possible to suppress offsets in focusing control due to wave-length variations of light.

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18-07-2006 дата публикации

PYRIMIDINE DERIVATIVES IN THE TREATMENT OF CANCER

Номер: PE20060504A1
Принадлежит: NOVARTIS AG

SE REFIERE A UN COMPUESTO DE FORMULA I, DONDE R0 ES H, R1 ES MONOCICLO SUSTITUIDO DE 6 ELEMENTOS O BICICLO-HETEROCICLO DE 10 ELEMENTOS CON 1-2 HETEROATOMOS DE N, O; R2 Y R3 JUNTO AL C Y N AL QUE ESTA UNIDO, FORMA UN HETEROCICLO QUE CONTIENE UN HETEROATOMO SELECCIONADO DE N, SUSTITUIDO O NO; R4 ES H; R5 ES HALOGENO; R6 Y R7 SON H; R8 ES H, ALCOXI C1-C7, CARBAMOILO SUSTITUIDO O NO POR ALQUILO C1-C7, ENTRE OTROS; R9 ES H; R10 ES H, HALOGENO, ALCOXI C1-C7. SON COMPUESTOS PREFERIDOS: 7-[5-CLORO-2-(2-METOXI-FENILAMINO)PIRIMIDI-4-NILAMINO]-2-METIL-4-PIPERAZI-1-NIL-2,3DIHIDRO-ISOINDO-1-LONA; 7-[5-CLORO-2-(2-METOXI-FENILAMINO)-PIRIMIDI-4-NILAMINO]-2-METIL-4-(4-METIL-PIPERAZI-1-NIL)-2,3-DIHIDRO-ISOINDO-1-LONA; ENTRE OTROS. SE REFIERE TAMBIEN A UNA COMPOSICION FERMACEUTICA Y A UN METODO DE PREPARACION. DICHOS COMPUESTOS SON INHIBIDORES DE CINASA NPM-ALK (ACTIVDAD TIROSIN-CINASA PROTEICA DEL LIGANDO INDEPENDIENTE DEL LINFOMA CINASA ANAPLASICA) UTILES EN EL TRATAMIENTO DE TUMOR DE PECHO, CANCER INTESTINAL, CANCER ESTOMACAL, MELANOMA, TUMOR DE VEJIGA, ENTRE OTROS

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14-08-2003 дата публикации

Optical pickup

Номер: DE10020622C2
Принадлежит: Sharp Corp

Подробнее
28-12-1993 дата публикации

External magnetic field device for a magnetooptical information recording and reproducing apparatus

Номер: CA1325676C
Принадлежит: Sharp Corp

ABSTRACT OF THE DISCLOSURE An external magnetic field device for a magnetooptical information recording and reproducing apparatus in which an external magnetic field to be applied to a magnetooptical information recording medium is modulated by supplying to a magnetic head an alternate current the polarity of which is changed according to information to be recorded. The device comprises an offset circuit for producing an offset in the alternate current. The direction of the offset is selected so as to increase the current level of the polarity by which the initial magnetization of the information recording medium is reversed. The direction of the offset may be selected so as to cancel the leakage magnetic field.

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27-03-2019 дата публикации

Scale

Номер: EP3459491A1
Принадлежит: GC Corp, GC Dental Industiral Corp

To provide a scale which makes it possible to adjust the temperature of a furnace so that a ceramic blank can be properly heated even if various conditions such as the combination of the used ceramic blank and investment, and the type and size of the furnace vary, the scale comprises: a scale part; and a base part, the scale part and the base part being formed of wax or resin, wherein the base part has a shape of protruding from part of the scale part, a size of the scale part is larger than that of the base part in a direction orthogonal to a protruding direction of the base part.

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27-07-2021 дата публикации

2,4-pyrimidinediamines, their uses, combination and pharmaceutical composition

Номер: BR122019017579B8
Принадлежит: NOVARTIS AG

a presente invenção se refere a derivados de pirimidina de fórmula (i) na qual r é selecionado de c16-10 arila, c5-10 heteroarila, c3-12 cicloal-quila e c3-10 heterocicloalquila; r0 - r6 são como aqui descritos; e seu uso para a produção de um medicamento para o tratamento ou a prevenção de uma doença que responde à inibição de fak e/ou alk e/ou zap-70 e/ou igf-ir.

Подробнее
11-01-2012 дата публикации

1,2-Disubstituted 4-benzylamino-pyrrolidine derivatives as CETP inhibitors useful for the treatment of diseases such as hyperlipidemia or arteriosclerosis

Номер: EP2404901A1
Принадлежит: NOVARTIS AG

The present invention provides a compound of formula (I): wherein the variants R1, R2, R3, R4, R6, R7 are as defined herein, and wherein said compound is an inhibitor of CETP, and thus can be employed for the treatment of a disorder or disease mediated by CETP or responsive to the inhibition of CETP.

Подробнее
27-07-1999 дата публикации

A display apparatus

Номер: CA2084103C
Принадлежит: Sharp Corp

A display apparatus includes a plurality of display devices arranged in one direction, each of the display devices having a display area; and a plurality of image transmission means corresponding to the respective display devices, one end face of each of the image transmission means being coupled to the display area of a corresponding display device, other end faces of the image transmission means corresponding to adjacent display devices being in contact with each other along at least one edge, the plurality of image transmission means being bent toward the one direction in which the display devices are arranged. Alternatively, a display apparatus of the invention includes a plurality of display devices disposed in two directions, each of the display devices having a display area; a plurality of image transmission means corresponding to the respective display devices, one end face of each of the image transmission means being coupled to the display area of a corresponding display device, otherend faces of the image transmission means corresponding to adjacent display devices being in contact with each other along at least two edges, some of the plurality of image transmission means each having inward facing slopes and outward facing slopes on two pairs of opposing faces, the outward facing slopes of the image transmission means being oriented in a direction in which the corresponding display device has no adjacent display devices.

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05-07-2007 дата публикации

Pyridinyl amine derivatives as inhibitors of cholesteryl ester transfer protein (cetp)

Номер: CA2634833A1
Принадлежит: Individual

The present invention relates to a compound of formula (I) or a pharmaceutically acceptable salt thereof, wherein the variables are as defined, useful as inhibitors of chlosteryl ester transfer protein.

Подробнее
19-11-2009 дата публикации

Organic compounds

Номер: US20090286790A1
Принадлежит: Individual

The present invention provides a compound of formula (I): wherein the variants R1, R2, R3, R4, R5, R6, R7 are as defined herein, and wherein said compound is an inhibitor of CETP, and thus can be employed for the treatment of a disorder or disease mediated by CETP or responsive to the inhibition of CETP.

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09-12-2010 дата публикации

Organic compounds

Номер: US20100311750A1
Принадлежит: Individual

The present invention provides a compound of formula (I): wherein the variants R1, R2, R3, R4, R6, R7 are as defined herein, and wherein said compound is an inhibitor of CETP, and thus can be employed for the treatment of a disorder or disease mediated by CETP or responsive to the inhibition of CETP.

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07-05-2020 дата публикации

Wax pattern surface-treating agent

Номер: AU2017238255B2
Принадлежит: GC Corp, GC Dental Industiral Corp

Provided is a wax pattern surface-treating agent which includes a solvent, boron nitride, and one or more surfactants selected from an anionic surfactant, a cationic surfactant, a non-ionic surfactant, and an amphoteric surfactant.

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31-12-2006 дата публикации

Spiro-substituted pyrrolopyrimidines

Номер: SI1601677T1
Принадлежит: NOVARTIS AG

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07-07-1993 дата публикации

A display apparatus

Номер: EP0550155A2
Принадлежит: Sharp Corp

A display apparatus of the invention includes: a plurality of display devices (111, 112, 113) arranged in one direction (A), each of the plurality of display devices (111, 112, 113) having a display area (111a, 112a, 113a); and a plurality of image transmission means (131, 132, 133) corresponding to the respective display devices (111, 112, 113), one end face (D) of each of the image transmission means (131, 132, 133) being coupled to a display area (111a, 112a, 113a) of the corresponding one of the display devices (111, 112, 113), other end faces (C) of the image transmission means (131, 132, 133) corresponding to the adjacent ones of the display devices (111, 112, 113) being in contact with each other, the plurality of image transmission means (131, 132, 133) being bent toward the one direction in which the display devices (111, 112, 113) are arranged.

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17-01-2019 дата публикации

Scale

Номер: AU2017396539A1
Принадлежит: GC Corp, GC Dental Industiral Corp

FUT/JP2017/023977 P848PCT (170449PCT) Abstract To provide a scale which makes it possible to adjust the temperature of a furnace so that a ceramic blank can be properly heated even if various conditions such 5 as the combination of the used ceramic blank and investment, and the type and size of the furnace vary, the scale includes: a scale part; and a base part, the scale part and the base part being formed of wax or resin, wherein the base part has a shape of protruding from part of the scale part, a size of the scale part is larger than that of the base part in a direction orthogonal to a protruding direction of the base part.

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18-10-1994 дата публикации

Optical head device

Номер: CA2018314C
Принадлежит: Sharp Corp

The invention discloses an optical head device having:-a diffraction grating element divided into a first diffraction grating and a second diffraction grating by a plane including an optical axis that connects a light emitting point on a semiconductor laser to a focal point on a recording medium such as an optical disk, so that the first and second diffraction gratings have a substantially equal diffraction angle, a substantially equal optical utilization efficiency, and different focal distances of first order diffracted lights, each of the first order diffracted lights being produced from a reflected light from the recording medium, at the respective diffraction gratings; and a photodetector positioned at a mid-position between two focal points produced when there occurs no focusing error, the photo-detecting means having a plurality of photo-detecting parts juxtaposed in a direction substantially orthogonal to an average diffracting direction of the diffraction grating element. In this optical head, the first diffraction grating and second diffraction grating are designed such that lights diffracted at the first diffraction grating and second diffraction grating are guided into the photo-detecting means to form light spots in the vicinity of centers of the corresponding photo-detecting parts, and the light spots are aligned in a direction substantially orthogonal to the average diffracting direction of the diffraction grating element. The above arrangement enables to produce a small size optical head device and improve the detection of focusing errors and tracking errors. The invention also discloses an optical head device having:-a diffraction grating element divided into first to forth diffraction gratings by two planes including the optical axis which connects the light emitting point of the semiconductor laser to the focal point on the recording medium. In this diffraction grating element, the first to forth diffraction gratings are paired off so that each ...

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24-06-2013 дата публикации

Stereoscopic imaging apparatus and electronic apparatus

Номер: JP2013126084A
Принадлежит: Sharp Corp

【課題】劣化のない良好な立体像を撮影できる立体像撮影装置を提供する。 【解決手段】同一被写体からの視差画像の2つの入射光を偏光方向が異なる2つの偏光に変換して、2つの偏光を合成する偏光合成部(109L,109R,P101,111,112)と、偏光合成部(109L,109R,P101,111,112)で合成された2つの偏光を複数のレンズを介して結像させるカメラ光学系(L2〜L8)と、2つの偏光が異なる像面に結像するように、カメラ光学系(L2〜L8)を透過した2つの偏光を分離する偏光分離部(P102)とを備える。上記偏光合成部(109L,109R,P101,111,112)は、2つの入射光のうちの一方をλ/4シート111(偏光変換素子)と反射ミラー112の反射面を用いて偏光方向を変換してカメラ光学系(L2〜L8)に導く。 【選択図】図2

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11-06-2009 дата публикации

1,2-disubstituted-4-benzylamino-pyrrolidine derivatives as cetp inhibitors useful for the treatment of diseases such as hyperli pidemia or arteriosclerosis

Номер: WO2009071509A1
Принадлежит: NOVARTIS AG

The present invention provides a compound of formula (I): wherein the variants R1, R2, R3, R4, R6, R7 are as defined herein, and wherein said compound is an inhibitor of CETP, and thus can be employed for the treatment of a disorder or disease mediated by CETP or responsive to the inhibition of CETP.

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29-03-2006 дата публикации

ORGANIC COMPOUNDS

Номер: GT200500229A
Принадлежит: NOVARTIS AG

LA PRESENTE INVENCIÓN SE REFIERE A NUEVOS DERIVADOS DE PIRIMIDINA DE FÓRMULA I, A SU PROCESO DE PRODUCCIÓN, A SU USO EN COMPOSICIONES FARMACÉUTICAS QUE LOS CONTIENEN. ESTOS COMPUESTOS SON USADOS EN EL TRATAMIENTO DE CÁNCER Y DE OTRAS ENFERMEDADES NEOPLÁSICAS: TUMOR DE MAMA, CÁNCER DE COLON, PRÓSTATA, OVARIOS Y PULMON; ENFERMEDADES DEL SISTEMA INMUNOLÓGICO, SNC, FALLAS AL CORAZÓN, HIPERTESIÓN, ETC.

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19-02-2016 дата публикации

Novel triazine derivative

Номер: NO20160292A1
Принадлежит: Carna Biosciences Inc

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20-04-2007 дата публикации

Pyrimidine derivatives.

Номер: MX2007002254A
Принадлежит: NOVARTIS AG

Novedosos derivados de pirimidina de la Formula (I) (ver Formula (I)): procesos para su produccion, su uso como productos farmaceuticos, y composiciones farmaceuticas que los comprenden.

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01-08-2007 дата публикации

PYRIMIDINE DERIVATIVES

Номер: MA28813B1
Принадлежит: NOVARTIS AG

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12-05-2011 дата публикации

Optical pointing device and electronic apparatus equipped with the same

Номер: JP2011096208A
Принадлежит: Sharp Corp

【課題】違和感の無い任意の外観色を有する薄型の光ポインティング装置を実現する。 【解決手段】被写体10に光を照射する光源16と、被写体10からの反射光を反射させて内部を導光させる導光部43を有するカバー部24と、カバー部24によって導光された光を受光する撮像素子15とを備えた光ポインティング装置30であって、カバー部24は、導光部43における被写体10を検知する領域を含む表面上に、光源16から照射された光を反射する光源光反射コート40と、可視光領域の光のうち、所定の波長帯の光のみを反射する特定色反射カラーコート41とを備え、光源光反射コート40は、導光部43における被写体10を検知する領域を避けて形成されている。 【選択図】図1

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02-03-2006 дата публикации

Pyrimidine derivatives

Номер: CA2575720A1
Принадлежит: Individual

Novel pyrimidine derivatives of formula (I) to processes for their production, their use as pharmaceuticals and to pharmaceutical compositions comprising them.

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08-06-1999 дата публикации

Advertisement addition selection system for pay channel

Номер: JPH11155137A
Принадлежит: ADAMS KK

(57)【要約】 【課題】 チャンネル数を増やさずにローコストで広告 が含まれない番組と広告が含まれる番組とを視聴者が選 択し得ることができ、また広告効果が反映される広告の 出稿料という的確で明瞭な料金システムとすることがで きる有料チャンネルに対する広告付加選択システムの構 築を目的とする。 【解決手段】 有料チャンネルの視聴開始時に、受信装 置1はテレビ受像機2に対し広告を付加した映像と広告 のない映像のどちらかを選択させるかを表示し、視聴者 が広告を付加した映像を選択した場合には、広告を付加 しない映像を選択した場合と同一のチャンネルにおいて その番組映像に広告映像を付加する。当該有料チャンネ ルの放送通信管理設備3には、視聴者ごとに広告を付加 した番組についての視聴料を減額して演算する演算装置 8を設ける。

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29-01-2009 дата публикации

Amino-piperidine derivatives as cetp inhibitors.

Номер: MX2009000646A
Принадлежит: NOVARTIS AG

La presente invención proporciona un compuesto de la fórmula (I): (ver fórmula (I)) en donde las variantes R1, R2, R3, R4, R5, R6, R7 son como se definen en la presente, y en donde este compuesto es un inhibidor de la proteína de transferencia de colesteril-éster (CETP), y por lo tanto, se puede emplear para el tratamiento de un trastorno o enfermedad mediada por la proteína de transferencia de colesteril-éster o que responda a la inhibición de la proteína de transferencia de colesteril-éster.

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29-01-2015 дата публикации

Amino-piperidine derivatives as cetp inhibitors

Номер: MY153262A
Принадлежит: NOVARTIS AG

THE PRESENT INVENTION PROVIDES A COMPOUND OF FORMULA (I), WHEREIN THE VARIANTS R1, R2, R3, R4, R5, R6, R7 ARE AS DEFINED HEREIN, AND WHEREIN SAID COMPOUND IS AN INHIBITOR OF CETP, AND THUS CAN BE EMPLOYED FOR THE TREATMENT OF A DISORDER OR DISEASE MEDIATED BY CETP OR RESPONSIVE TO THE INHIBITION OF CETP.

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04-07-1996 дата публикации

Optical scanner.

Номер: DE69023252T2
Принадлежит: Sharp Corp

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22-12-2010 дата публикации

Σπειροϋποκαθιστουμενες πυρρολοπυριμιδινες

Номер: CY1105637T1
Принадлежит: NOVARTIS AG

Η εφεύρεση παρέχει ενώσεις του τύπου (Ι) ή ένα φαρμακευτικά αποδεκτό άλας ή εστέρα αυτού του τύπου (I) όπου τα σύμβολα έχουν την έννοια που ορίζεται στην περιγραφή. Οι εν λόγω ενώσεις είναι αναστολείς της καθεψίνης Κ ή / και της καθεψίνης S και είναι χρήσιμες για τη θεραπεία ασθενειών και ιατρικών καταστάσεων στις οποίες εμπλέκεται η καθεψίνη Κ ή / και η καθεψίνη S, π.χ. διάφορες διαταραχές όπως είναι ο νευροπαθητικός πόνος, η φλόγωση, η ρευματοειδής αρθρίτιδα, η οστεοαρθρίτιδα, η οστεοπόρωση, η πολλαπλή σκλήρωση και οι όγκοι.

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15-07-2006 дата публикации

Spirosubstituierte pyrrolopyrimidine

Номер: ATE331718T1
Принадлежит: Novartis Pharma Gmbh

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31-07-2008 дата публикации

波長判定装置、およびレーザ装置

Номер: JP2008177470A
Принадлежит: Sharp Corp

【課題】小型かつ低コストな波長判定装置、および、その波長判定装置を備えるレーザ装置を提供する。 【解決手段】波長判定装置は、光学素子22と、干渉光を検出する光検出器23とを備える。光学素子22は、入射光を反射させる第1の反射部(反射部12)および第2の反射部(裏面2E)を含み、かつ、第1の反射部からの反射光と第2の反射部からの反射光とを干渉させて干渉光を生じさせる。反射部12は、裏面2Eからの距離が互いに異なる複数の反射面(表面2A〜2D)を有する。表面2A〜2Dの各々は裏面2Eと平行である。光学素子22を形成する際に、構成部材を少なくすることが可能になるとともに、表面2A〜2Dおよび裏面2Eを容易に形成することが可能になる。 【選択図】図3

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15-07-2011 дата публикации

Pyrimidinderivate

Номер: ATE512960T1
Принадлежит: NOVARTIS AG

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28-03-2024 дата публикации

Glass composition and dental composition

Номер: US20240101466A1
Принадлежит: GC Corp

A glass composition contains cesium (Cs), at least one of potassium (K) or sodium (Na), and silicon (Si), wherein a content of the cesium (Cs) in terms of oxide is 9% by mass or more, wherein when the potassium (K) is contained in the glass composition, a content of the potassium (K) in terms of oxide is 5% by mass or more, wherein when the sodium (Na) is contained in the glass composition, a content of the sodium (Na) in terms of oxide is 1% by mass or more, and wherein the glass composition does not contain barium (Ba) or contains 0.5% by mass or less of barium (Ba) in terms of oxide.

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07-02-2008 дата публикации

Optical Pickup Apparatus

Номер: US20080031106A1
Принадлежит: Sharp Corp

An optical pickup apparatus includes a diffraction grating having a grating constant that is entirely uniform. The duty ratio referred to as L/G duty that is the ratio between a land L and a groove G and defined by the expression UG duty (%)=L/(L+G)×100 is continuously changed in the direction orthogonal to grating grooves of the diffraction grating. For example, the L/G duty ratio is set close to 50% in a central portion of the diffraction grating while the duty is set close to 100% in an outer peripheral portion of the diffraction grating. Accordingly, the number of components of the optical pickup is reduced while loss in light quantity in recording and reproduction can be minimized.

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29-05-2008 дата публикации

波長検出装置および波長検出方法

Номер: JP2008122096A
Принадлежит: Sharp Corp

【課題】光学部品の位置ずれによる波長検出の誤差を防ぐことが可能な波長検出装置および波長検出方法を提供する。 【解決手段】レーザ光源装置10Aは、光ビームを出射するレーザダイオード1と、光ビームを0次光を含む複数の第1回折光に回折し、複数の第1回折光の一部をレーザダイオード1に帰還させる回折格子3と、複数の第1回折光の0次光を第1および第2の光ビームに分離し、第1の光ビームを外部に出射するビームスプリッタ4と、第2の光ビームを第3および第4の回折光を含む複数の第2回折光に回折する回折格子5と、第3の回折光を複数の第1受光部で受光する2分割フォトディテクタ8と、第4の回折光を複数の第2受光部で受光する2分割フォトディテクタ9と、複数の第1受光部の差動信号と複数の第2受光部の差動信号とに基づいて光ビームの波長を検出する演算部とを備える。 【選択図】図1

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16-10-2023 дата публикации

ガラス組成物

Номер: JP2023151500A
Принадлежит: GC Corp, GC Dental Industiral Corp

【課題】X線造影性と審美性に優れたガラス組成物を提供すること。【解決手段】ガラス組成物は、ガドリニウム(Gd)とセシウム(Cs)の少なくとも一方と、ケイ素(Si)とを含む。ガラス組成物は、酸化物換算で、酸化ガドリニウムと酸化セシウムの合計含有量が1質量%以上であって、酸化ケイ素の含有量が30質量%以上である。【選択図】なし

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20-05-2013 дата публикации

厚み測定方法、厚み測定装置、および厚み測定システム

Номер: JP2013096835A
Принадлежит: Sharp Corp

【課題】立体構造を有する物体の厚み分布を、短時間に、かつ容易に測定する。 【解決手段】厚み測定方法は、測定対象物6に光を照射する光照射工程(S1)と、測定対象物6に照射された光が、測定対象物6を透過しているときに、測定対象物6への光の照射方向とは異なる所定の方向から、測定対象物6を撮像する撮像工程(S2)と、その撮像画像に基づいて、測定対象物6の厚み分布を測定する測定工程(S3)と、を含む。 【選択図】図1

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11-12-2008 дата публикации

情報記録装置、情報再生装置および情報記録媒体

Номер: JP2008298996A
Принадлежит: Sharp Corp

【課題】温度変化等により生じるホログラム記録媒体のディメンジョン変化によるデータ再生時のデータ情報の信頼性をさらに高める情報記録装置を提供する。 【解決手段】記録データ領域MA内において、最初のページに対応するイメージ情報(データ情報)が記録される。また、記録データ領域MA内にイメージ情報を再生する際の最適な再生光の波長を設定するために用いる制御情報である波長検出情報が記録される。具体的には、本例においては、データ情報を記録した際の記録波長よりも長い波長で第1の波長検出情報を記録し、データ情報を記録した際の記録波長よりも短い波長で第2の波長検出情報を記録する。 【選択図】図2

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22-11-2012 дата публикации

光ポインティング装置及びそれを備えた電子機器

Номер: JP2012230645A
Принадлежит: Sharp Corp

【課題】組み立て性の向上を図ることにより高精度化及び低コスト化を図ると共に、遮光性能の優れた光ポインティング装置及びそれを備えた電子機器を提供する。 【解決手段】光ポインティング装置1Aでは、光学カバー30には、被写体2が接触する接触面31と、導光される光を撮像素子13に導く結像用レンズ33とが一体に形成されている。光源12及び撮像素子13は、光学カバー30の接触面31とは反対側に配設されている。遮光カバー20には、結像用レンズ33から撮像素子13への光に対して絞りとして作用するアパーチャー21と、迷光のうち光源12から撮像素子13への入射光を遮光する遮光カバー第1突起20eと、迷光のうち光学カバー30の外部から撮像素子13への入射光を遮光する遮光カバースカート部22とが形成されている。 【選択図】図1

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