Compounds and compositions for cognition-enhancement, methods of making, and methods of treating

Muscarinic agonists, which are useful for stimulating muscarinic receptors and treating cognitive disorders, are provided. Methods of synthesizing such agonists also are provided. Also provided are compositions for enhancing cognitive function in subjects such as humans, the compositions comprising a muscarinic agonist or a pharmaceutically suitable form thereof. Also provided are methods of treating animals such as humans by administering such compositions.

MICROTENSIOMETER SENSOR, PROBE AND METHOD OF USE

A microtensiometer sensor includes a substrate layer fluidly coupled to an enclosed reservoir. A porous membrane is disposed on a surface of the substrate layer. The membrane defines a liquid side fluidly coupled to the reservoir and a vapor side fluidly coupled to a vapor interface. The porous membrane includes a plurality of through holes fluidly coupling the liquid reservoir to the vapor interface, and a nanoporous filler material disposed within the plurality of through holes. The filler material includes a plurality of open pores having a maximum diameter in the range of 0.2 to 200 nanometers. In one embodiment, the microtensiometer sensor includes a molecular membrane disposed adjacent to the vapor side of the porous membrane. In one example, the molecular membrane is formed of a highly crystalline polytetrafluoroethylene polymer having a microstructure characterized by nodes interconnected by fibrils. In one application, the microtensiometer sensor may be used in a probe to measure the average water potential within a network of plant or tree xylem. In another application, the microtensiometer sensor may be useful in real-time determination of the water potential in soil. 138.-. (canceled)39. A microfluidic probe comprising:a probe body; anda microtensiometer sensor coupled to the probe body, the microtensiometer sensor comprising a substrate layer fluidly coupled to an enclosed reservoir, a porous membrane disposed on a surface of the substrate layer, the membrane defining a liquid side fluidly coupled to the reservoir and a vapor side fluidly coupled to a vapor interface, the membrane comprising a plurality of pores extending from the vapor interface to the reservoir, the pores having a maximum diameter in the range of 0.2 to 200 nanometers, the microtensiometer sensor further comprising a pressure sensor coupled to the reservoir for measuring changes to a pressure of a liquid disposed within the reservoir.40. The microfluidic probe of claim 39 , wherein ...

PROCESS FOR THE CONVERSION OF ALIPHATIC CYCLIC AMINES TO ALIPHATIC DIAMINES

The instant invention is a process for the conversion of aliphatic cyclic amines to aliphatic diamines. The process for conversion of aliphatic cyclic amines to aliphatic diamines comprises the steps of: (1) selecting one or more cyclic amines; (2) contacting said one or more cyclic amines with ammonia and hydrogen, optionally water, and optionally one or more solvents in the presence of one or more heterogeneous metal based catalyst systems at a temperature in the range of from 120° C. to about 250° C. and a pressure in the range of from 700 to 3500 psig for a period in the range of at least one hour or more in one or more reactor systems; (3) forming a product mixture comprising one or more aliphatic diamine, optionally a portion of said one or more cyclic amines, optionally a portion of said ammonia, optionally a portion of said hydrogen, optionally water, and optionally a portion of said one or more solvents; (4) removing said product mixture from the reactor system; (5) removing at least a portion of said portion of ammonia, said portion of hydrogen, or mixture thereof from said product mixture via distillation; (6) removing at least a portion of said portion of water via distillation; (7) removing at least a portion of said portion of one or more optional solvents via distillation; (8) removing at least a portion of said portion of one or more cyclic amines; (9) thereby separating said one or more aliphatic diamines from said product mixture; and (10) thereby converting said one or more cyclic amines to one or more aliphatic diamines. 1. A process for conversion of aliphatic cyclic amines to aliphatic diamines comprising the steps of:selecting one or more cyclic amines;contacting said one or more cyclic amines with ammonia and hydrogen, optionally water, and optionally one or more solvents in the presence of one or more heterogeneous metal based catalyst systems at a temperature in the range of from 120° C. to about 250° C. and a pressure in the range of from ...

Process for separating one or more aliphatic diamines from reductive amination reaction solvents and impurities

The instant invention provides a process for separating one or more aliphatic diamines from reductive amination reaction solvents and impurities, and aliphatic diamines obtained via such a process. The process for separating one or more aliphatic diamines from reductive amination reaction solvents and impurities according to the instant invention comprises the steps of: (1) feeding one or more cycloaliphatic cyanoaldehydes, hydrogen, ammonia, and optionally one or more solvents into a continuous reductive amination reactor system; (2) contacting said one or more cycloaliphatic cyanoaldehydes, hydrogen, and ammonia with each other in the presence of one or more heterogeneous metal based catalyst systems at a temperature in the range of from 80° C. to about 160° C. and a pressure in the range of from 700 to 3500 psig; (3) thereby forming a product mixture comprising one or more cycloaliphatic diamines, optionally one or more bicyclic by-products, optionally one or more cycloaliphatic aminonitriles, optionally one or more cycloaliphatic aminoalcohols, optionally one or more oligomeric by-products, ammonia, water, hydrogen, and optionally one or more solvents; (4) removing said product mixture from the reactor system; (5) removing at least a portion of said ammonia, said hydrogen, or mixture thereof from said product mixture via distillation; (6) removing at least a portion of said water and said one or more optional solvents via distillation; (7) removing at least a portion of one or more optional bicyclic by-products via distillation; (8) removing one or more optional cycloaliphatic aminonitriles, one or more optional cycloaliphatic aminoalcohols, one or more optional oligomeric by-products via distillation; and (9) thereby separating said one or more cycloaliphatic diamines from said product mixture.

PROCESS FOR REDUCTIVE AMINATION OF ALIPHATIC CYANOALDEHYDES TO ALIPHATIC DIAMINES

The instant invention provides a process for reductive amination of aliphatic cyanoaldehydes to aliphatic diamines, and aliphatic diamines produced via such method. The process for reductive amination of aliphatic cyanoaldehydes to aliphatic diamines comprises the steps of: (1) providing a mixture of one or more cycloaliphatic cyanoaldehydes, optionally water, and optionally one or more solvents, wherein said one or more cycloaliphatic cyanoaldehydes are selected from the group consisting of 1,3-cyanocyclohexane carboxaldehyde, 1,4-cyanocyclohexane carboxaldehyde, mixtures thereof, and combinations thereof; (2) contacting said mixture with a metal carbonate based solid bed or a weak base anion exchange resin bed at a temperature in the range of 15 to 40° C. for a period of at least 1 minute or more, for example 5 minutes or more; (3) thereby treating said mixture, wherein said treated mixture has a pH in the range of 6 to 9; (4) feeding said treated mixture, hydrogen, and ammonia into a continuous reductive amination reactor system; (6) contacting said treated mixture, hydrogen, and ammonia with each other in the presence of one or more heterogeneous metal based catalyst systems at a temperature in the range of from 80° C. to about 160° C. and a pressure in the range of from 700 to 3500 psig; (7) thereby producing one or more cycloaliphatic diamines, wherein said one or more cycloaliphatic diamines are diamines selected from the group consisting of 1,3-bis(aminomethyl)cyclohexane, 1,4-bis(aminomethyl)cyclohexane, combinations thereof, and mixtures thereof. 1. A process for reductive amination of aliphatic cyanoaldehydes to aliphatic diamines comprising the steps of:providing a mixture of one or more cycloaliphatic cyanoaldehydes, optionally water and optionally one or more solvents, wherein said one or more cycloaliphatic cyanoaldehydes are selected from the group consisting of 1,3-cyanocyclohexane carboxaldehyde, 1,4-cyanocyclohexane carboxaldehyde, mixtures ...

CYCLOALIPHATIC DIAMINES AND METHOD OF MAKING THE SAME

The instant invention provides cycloaliphatic diamines and a method of making the same. The cycloaliphatic diamines according to the instant invention comprise the reaction product of one or more cycloaliphatic cyanoaldehydes selected from the group consisting of 1,3-cyanocyclohexane carboxaldehyde, 1,4-cyanocyclohexane carboxaldehyde, mixtures thereof, and combinations thereof, hydrogen, and ammonia fed into a continuous reductive amination reactor system; wherein the one or more cycloaliphatic cyanoaldehydes, hydrogen, and ammonia are contacted with each other in the presence of one or more heterogeneous metal based catalyst systems at a temperature in the range of from 80° C. to about 160° C. and a pressure in the range of from 700 to 3500 psig; and wherein one or more cycloaliphatic diamines are formed; and wherein said one or more cycloaliphatic diamines are selected from the group consisting of 1,3-bis(aminomethyl)cyclohexane, 1,4-bis(aminomethyl)cyclohexane, combinations thereof, and mixtures thereof. 1. A process for producing cycloaliphatic diamines comprising the steps of:feeding one or more cycloaliphatic cyanoaldehydes selected from the group consisting of 3-cyanocyclohexane-1-carboxaldehyde, 4-cyanocyclohexane-1-carboxaldehyde, mixtures thereof, and combinations thereof, hydrogen, and ammonia into a reductive amination reactor system;contacting said one or more cycloaliphatic cyanoaldehydes, hydrogen, and ammonia with each other in the presence of one or more heterogeneous metal based catalyst systems at a temperature in the range of from 80° C. to about 160° C. and a pressure in the range of from 700 to 3500 psig;thereby forming one or more cycloaliphatic diamines, wherein said one or more cycloaliphatic diamines are diamines selected from the group consisting of 1,3-bis(aminomethyl)cyclohexane, 1,4-bis(aminomethyl)cyclohexane, combinations thereof, and mixtures thereof.2. One or more cycloaliphatic diamines comprising the reaction product of:one or ...

Multi-Dispersant Lubricating Composition

The present invention relates to a lubricating composition containing a corrosion inhibitor compound and a mixture of two or more dispersants, wherein 0 mole % to less than 50 mole % of the second dispersant molecules contain a carbocyclic ring. The invention further provides a method for lubricating a mechanical device using the lubricating composition. 1. A lubricating composition comprising:(a) an oil of lubricating viscosity; (i) a first dispersant substrate;', '(ii) a thiadiazole compound;', '(iii) a borating agent; and', '(iv) a dicarboxylic acid of an aromatic compound selected from the group consisting of 1,3 diacids and 1,4 diacids, and', '(v) optionally a phosphorus acid compound, said heating being sufficient to provide a product of (i), (ii), (iii) and (iv) and optionally (v), which is soluble in an oil of lubricating viscosity;, '(b) a first dispersant comprising a product prepared by heating together(c) a second dispersant, wherein 0 mole % to less than 50 mole % of the second dispersant molecules contain a carbocyclic ring; and(d) a corrosion inhibitor.2. The lubricating composition of claim 1 , wherein the corrosion inhibitor comprises an oil soluble 2 claim 1 ,5-dimercapto-1 claim 1 ,3 claim 1 ,4-thiadiazole claim 1 , other than (b).3. The lubricating composition of claim 2 , wherein the corrosion inhibitor is present in the range of 0.005 wt % to 5 wt % of the lubricating composition.4. The lubricating composition of claim 1 , wherein the first dispersant is prepared by an “ene” reaction.5. The lubricating composition of claim 1 , wherein the second dispersant is prepared from a succinic anhydride from an “ene” reaction.6. The lubricating composition of claim 1 , wherein 0 mole % to less than 20 mole % of the second dispersant molecules contain a carbocyclic ring.7. The lubricating composition of claim 1 , wherein the first dispersant and second dispersant both have a CO:N ratio of 2:1 to 1:10.8. The lubricating composition of claim 1 , wherein the ...

Process for improving the catalytic activity of catalyst systems for reductive amination of aliphatic cyanoaldehydes to aliphatic diamines

The instant invention provides a process for improving catalytic activity of catalyst systems for reductive amination of aliphatic cyanoaldehydes to aliphatic diamines. The process for improving catalytic activity of catalyst systems for reductive amination of aliphatic cyanoaldehydes to aliphatic diamines comprises the steps of: (1) feeding ammonia, optionally hydrogen, and optionally one or more solvents over one or more heterogeneous metal based catalyst systems having a reduced catalytic activity for a period of greater than 1 hour at a temperature in the range of from 50° C. to 500° C.; wherein said one or more heterogeneous metal based catalyst systems have a yield of less than 90 percent based on the molar conversion of cyanoaldehydes to diamines; and (2) thereby improving the catalytic activity of said one or more heterogeneous metal based catalyst systems.

Lubricating Composition Containing an Ester

The invention relates to a method of lubricating a limited slip differential comprising supplying to the limited slip differential a lubricating composition containing (a) an oil of lubricating viscosity, and (b) a C4-30-diester of a dicarboxylic acid. The invention further provides for the use of the C4-30-diester of a dicarboxylic acid as a friction modifier, typically in a limited slip differential. 123-. (canceled)24. A method of lubricating a limited slip differential comprising supplying to the limited slip differential a lubricating composition comprising (a) an oil of lubricating viscosity , and (b) a C-diester of adipic acid , wherein the C-diester of adipic acid is present at 0.01 wt % to less than 1 wt % of the lubricating composition.25. The method of claim 24 , wherein the C-diester of adipic acid is present at 0.05 wt % to 0.5 wt % of the lubricating composition.26. The method of claim 24 , wherein the C-diester of adipic acid is present at 0.1 wt % to 0.3 wt % of the lubricating composition.27. The method of claim 24 , wherein the alcohol-derived portion of the diester is C.28. The method of claim 24 , wherein the alcohol-derived portion of the diester is C.29. The method of claim 24 , wherein the alcohol-derived portion of the diester is C.30. The method of claim 24 , wherein the ester groups of the diester are branched.31. The method of claim 24 , wherein the lubricating composition further comprises a phosphorus containing compound claim 24 , wherein the phosphorus containing compound is an amine salt of a phosphoric acid ester.32. The method of claim 24 , wherein the lubricating composition comprises (a) an oil of lubricating viscosity claim 24 , and a friction modifier package consisting of a C-diester of adipic acid claim 24 , and a phosphorus containing compound claim 24 , wherein the phosphorus containing compound is an amine salt of a phosphoric acid ester.33. The method of claim 31 , wherein the phosphorus compound is present at 0.01 wt % to ...

Cognition Enhancing Compounds and Compositions, Methods of Making, and Methods of Treating

The invention relates generally to muscarinic agonists, which are useful for stimulating muscarine receptors, and treating cognitive disorders. Included among the muscarinic agonists disclosed herein are oxadiazole derivatives, compositions, and preparations thereof. Methods of synthesizing oxadiazole compounds also are provided. This disclosure also relates in part to compositions for enhancing cognitive function in subjects such as humans, the compositions comprising a muscarinic agonist or a pharmaceutically suitable form thereof. This disclosure relates in part to methods of treating animals such as humans by administering such compositions. 312-. (canceled)13. The compound of selected from the group consisting of5-((1R,5R)-3-azabicyclo[3.1.0]hexan-1-yl)-3-methyl-d3-1,2,4-oxadiazole,5-((1R,5R)-2,2-d2-3-azabicyclo[3.1.0]hexan-1-yl)-3-methyl-1,2,4-oxadiazole,5-((1R,5R)-4,4-d2-3-azabicyclo[3.1.0]hexan-1-yl)-3-methyl-1,2,4-oxadiazole,5-((1R,5R)-2,2,4,4-d4-3-azabicyclo[3.1.0]hexan-1-yl)-3-methyl-1,2,4-oxadiazole,5-((1R,5R)-4,4,5-d3-3-azabicyclo[3.1.0]hexan-1-yl)-3-methyl-1,2,4-oxadiazole,5-((1R,5R)-6,6-d2-3-azabicyclo[3.1.0]hexan-1-yl)-3-methyl-1,2,4-oxadiazole,5-((1S,5S)-3-azabicyclo[3.1.0]hexan-1-yl)-3-methyl-d3-1,2,4-oxadiazole,5-((1S,5S)-2,2-d2-3-azabicyclo[3.1.0]hexan-1-yl)-3-methyl-1,2,4-oxadiazole,5-((1S,1S)-4,4-d2-3-azabicyclo[3.1.0]hexan-1-yl)-3-methyl-1,2,4-oxadiazole,5-((1S,5S)-2,2,4,4-d4-3-azabicyclo[3.1.0]hexan-1-yl)-3-methyl-1,2,4-oxadiazole,5-((1S,5S)-4,4,5-d3-3-azabicyclo[3.1.0]hexan-1-yl)-3-methyl-1,2,4-oxadiazole, and5-((1S,5S)-6,6-d2-3-azabicyclo[3.1.0]hexan-1-yl)-3-methyl-1,2,4-oxadiazole.1540-. (canceled)41. A pharmaceutically acceptable composition comprising a compound of and a pharmaceutically acceptable carrier.42. A method comprising administering an effective amount of a compound or composition of to a subject in need thereof.43. The method of claim 42 , wherein the subject is suffering from presenile dementia claim 42 , senile dementia ...

Lubricant Composition Comprising Anti-Foam Agents

The disclosed invention relates to a multigrade lubricant composition which can be used for numerous lubricant applications, but is particularly useful for lubricating a diesel engine. The lubricant composition comprises an oil of lubricating viscosity, a detergent, a dispersant, a viscosity index improver, and a combination of anti-foam agents. The lubricant composition may be used for providing enhanced fuel economy and avoiding air entrainment problems when used in lubricating diesel engines. 1. A lubricant composition , comprising:an oil of lubricating viscosity;a detergent; [{'sup': '2', 'a first anti-foam agent comprising a polydimethyl siloxane having a kinetic viscosity (absent solvent) at 25° C. in the range from about 10,000 to about 50,000 mm/s (cSt);'}, {'sup': '2', 'a second anti-foam agent comprising a polydimethyl siloxane having a kinetic viscosity (absent solvent) at 25° C. in the range from about 80,000 to about 120,000 mm/s (cSt); and'}, {'sup': '2', 'a third anti-foam agent comprising a fluorinated polysiloxane having a kinematic viscosity (absent solvent) at 25° C. in the range from about 50 to about 500 mm/s (cSt).'}], 'a dispersant;'}2. The composition of wherein the composition is a multigrade composition claim 1 , further comprising a viscosity index improver3. The composition of wherein the composition further comprises at least one of an antiwear agent claim 1 , an antioxidant claim 1 , a friction modifier claim 1 , a pour point depressant claim 1 , a metal deactivator claim 1 , a corrosion inhibitor claim 1 , a dispersant viscosity modifier claim 1 , an extreme pressure agent claim 1 , a demulsifier claim 1 , a seal swelling agent claim 1 , or a mixture of two or more thereof.47.-. (canceled)8. The composition of wherein the lubricant composition has a kinematic viscosity at 100° C. of up to about 12.5 cSt.9. (canceled)10. The composition of wherein the oil of lubricating viscosity comprises a Group III oil.11. The composition of wherein ...

Continuously Variable Transmission Fluid with Extended Anti-Shudder Durability

A lubricant composition comprising (a) an oil of lubricating viscosity; (b) at least two nitrogen-containing materials, comprising (i) at least one amide of the formula RC(O)NRRand (ii) at least one tertiary amine being represented by the formula RRNRwhere Rand Rare alkyl groups of at least 6 carbon atoms and Ris a polyhydroxyl-containing alkyl group or a polyhydroxyl-containing alkoxyalkyl group; (c) a functionalized dispersant component, and (d) at least one diallyl phosphite, provides good lubricant performance for a continuously variable transmission. 1. A lubricant composition comprising:(a) an oil of lubricating viscosity {'br': None, 'sup': 3', '1', '2, 'RC(O)NRR'}, '(i) about 0.2 to about 3 percent by weight of at least one amide represented by the formula'}, '(b) at least two nitrogen-containing materials, comprising at least one each of{'sup': 1', '2', '3, 'claim-text': {'br': None, 'sup': 4', '5', '6, 'RRNR'}, '(ii) about 0.03 to about 0.5 percent by weight of at least one tertiary amine represented by the formula'}, 'wherein Rand Rare each independently hydrocarbyl groups of at least 6 carbon atoms and Ris a hydroxyalkyl group of 1 to 6 carbon atoms or a group formed by the condensation of said hydroxyalkyl group, through a hydroxyl group thereof, with an acylating agent and'}{'sup': 4', '5', '6, 'wherein Rand Rare each independently alkyl groups of at least 6 carbon atoms and Ris a polyhydroxy-containing alkyl group or a polyhydroxy-containing alkoxyalkyl group;'} (i) 2,5-dimercapto-1,3,4-thiadiazole or hydrocarbyl-substituted 2,5-dimercapto-1,3,4-thiadiazole and', '(ii) a borating agent, and optionally', '(iii) an inorganic phosphorus compound, and optionally', '(iv) an aromatic 1,3-dicarboxylic acid or 1,4-dicarboxylic acid, or a reactive equivalent thereof;, '(c) about 2 to about 5 percent by weight of a functionalized dispersant component, comprising one or more dispersants, treated with'}(d) about 0.22 to about 2 weight percent of at least one di- ...

MEMS MICROTENSIOMETER

A device for measuring a chemical potential of a fluid in a plant tissue includes a cavity disposed within a sensor body as a liquid reservoir. The cavity is configured for containing therein a liquid, and the cavity including at least one opening. At least two porous membrane layers are positioned at least in part over the at least one opening of the cavity for selectively allowing water transfer between the plant fluid and the liquid in the cavity. At least one pressure sensor is configured for detecting changes in pressure of the liquid in the cavity. The changes are related to a chemical potential of the fluid in the plant tissue. 118-. (canceled)19. A device for measuring a chemical potential of a fluid in a plant tissue , said device comprising:a cavity disposed within a sensor body as a liquid reservoir, said cavity configured for containing therein a liquid, said cavity comprising at least one opening;at least two porous membrane layers positioned at least in part over said at least one opening of said cavity for selectively allowing water transfer between the plant fluid and the liquid in the cavity; andat least one pressure sensor configured for detecting changes in pressure of the liquid in said cavity, said changes are related to a chemical potential of the fluid in the plant tissue.20. The device according to claim 19 , wherein at least one of said at least two porous membrane layers comprises a reverse osmotic membrane or a nanoporous membrane.21. The device according to claim 19 , wherein said at least one pressure sensor comprises at least one piezoelectric transducer sensor or at least one strain gauge sensor.22. The device according to claim 19 , wherein said device comprises a Micro Electro-Mechanical System (MEMS).23. The device according to claim 19 , wherein said cavity is configured for being hydraulically connected to a vascular conduit of the plant claim 19 , via a space of the plant tissue claim 19 , wherein said chemical potential ...

Gaming Machine with Integral Features for Ease of Assembly

A gaming machine includes a monitor subassembly, a game control core, and a structural frame that may be manufactured and shipped separately to a final destination and assembled on-site. The gaming machine components include integral features and components that facilitate a novel and efficient assembly process.

LINEAR PELTON TURBINE

Systems and methods related to linear turbine systems are presented. Each embodiment described herein may be designed as a single-stage, linear, impulse turbine system. In an embodiment, a linear turbine includes a first shaft extending along a first axis; a second shaft extending along a second axis, the second axis being separated from and substantially parallel to the first axis; a first plurality of buckets to travel a first continuous path around the first shaft and the second shaft along a first plane, the first path including a first substantially linear path segment between the first axis and the second axis; and a nozzle configured to direct a first fluid jet to contact the first plurality of buckets in the first linear path segment. 138.-. (canceled)39. A linear turbine system , linear turbine system comprising:a linear turbine; anda nozzle configured to provide a fluid jet to the turbine, the nozzle comprising:an inlet portion for receiving a volume of fluid, the inlet portion having a cross-section;a first outlet portion terminating in a first substantially rectilinear opening to direct a first rectilinear jet of fluid outward to contact the linear turbine;a second outlet portion terminating in a second substantially rectilinear opening to direct a second rectilinear jet of fluid outward to contact the linear turbine; anda bifurcation positioned between the inlet portion and the first and second outlet portions to divide the volume of fluid into the first outlet portion and the second outlet portion.40. The nozzle of claim 39 , wherein the first outlet portion directs the first rectilinear jet of fluid into the linear turbine at an angle ranging from approximately 25° to approximately 35°.41. A linear turbine system claim 39 , the linear turbine system comprising:a single-stage linear turbine;a free jet nozzle to supply a fluid jet to the turbine; anda housing configured to isolate the linear turbine and nozzle from an external atmosphere, the housing ...

Linear Pelton Turbine

Systems and methods related to linear turbine systems are presented. Each embodiment described herein may be designed as a single-stage, linear, impulse turbine system. In an embodiment, a linear turbine includes a first shaft extending along a first axis; a second shaft extending along a second axis, the second axis being separated from and substantially parallel to the first axis; a first plurality of buckets to travel a first continuous path around the first shaft and the second shaft along a first plane, the first path including a first substantially linear path segment between the first axis and the second axis; and a nozzle configured to direct a first fluid jet to contact the first plurality of buckets in the first linear path segment.

AUTOMATED INTELLIGENT DATA SCRAPING AND VERIFICATION

A server computer system for parsing non-uniformly presented data from a variety of unique non-uniform third-party web portals can comprise a scripting processor configured to automatically execute a web-portal specific script for each of the one or more third-party web portals accessed by a network communication device. Each of the web-portal specific scripts can be configured to imitate inputs from a user input device and to automatically adapt interactions with each of the one or more third-party web portals to access and parse data elements from one or more non-uniformly available data fields. Further, the server computer system can comprise a database processor configured to compare a first set of data received from the one or more non-uniformly available data fields with a second set of data, which is stored within the local database device. 1. A computer-implemented method for intelligently loading and verifying data in non-uniform formats against a second set of data , the method executed on a computer system comprising one or more processors , the method comprising:accessing a particular third-party software portal; interacting with the particular third-party software portal by imitating inputs from a user input device; and', 'automatically adapting interactions with the particular third-party software portal to access and parse data elements from one or more data fields;, 'executing computer code that is unique to the particular third-party software portal, wherein the computer code performs the method ofcomparing a first set of data received from the one or more data fields with the second set of data, wherein the second set of data comprises specific data entries of interest that are stored within a first locally accessible database; andgenerating a report based upon a comparison of the first set of data and the second set of data.2. The computer-implemented method as recited in claim 1 , wherein the one or more data fields comprise non-uniformly ...

PORTABLE AND TRACKABLE SECURITY BOX AND METHOD FOR DELIVERING AND TRACKING SECURITY BOX

A shipping box system and method are provided in which a shipping box has a container having a bottom surface and a plurality of walls, the container walls forming a perimeter about a container cavity. The shipping box further has a lid having a top surface and walls, the lid walls forming a perimeter about a lid cavity. The box further provides a sensor module for determining a physical location and orientation of the container, a computations module for evaluating data retrieved from the sensor module, and a locking assembly for locking the container and the lid in a closed configuration. The container and the lid are sized to nest, such that when the lid is fixed to the container, the container cavity and the lid cavity occupy substantially the same space and the container walls and the lid walls overlap. 1. A shipping box system comprising a first shipping box having:a container having a bottom surface and a plurality of container walls extending from the bottom surface, the container walls forming a perimeter about a container cavity;a lid having a top surface and a plurality of lid walls extending from the top surface, the lid walls forming a perimeter about a lid cavity;a sensor module for determining a physical location and orientation of the container;a computations module for evaluating data retrieved from the sensor module;a locking assembly for locking the container and the lid in a closed configuration;wherein the container and the lid are sized to nest, such that when the lid is fixed to the container, the container cavity and the lid cavity occupy substantially the same space and the container walls and the lid walls overlap.2. The shipping box system of claim 1 , wherein the perimeter about the lid cavity is larger than the perimeter about the container cavity claim 1 , such that the container is nested within the lid claim 1 , and wherein the container walls and the lid walls have substantially similar heights claim 1 , such that the container is ...

LUBRICATION OF AN AUTOMATIC TRANSMISSION WITH REDUCED WEAR ON A NEEDLE BEARING

A lubricant composition comprising (a) an oil having a kinematic viscosity at 100° C. of 2.2 to 3.7 mm/s; at least one borate ester having an alkyl group of 4 to 18 carbon atoms in an amount to provide 25 to 150 parts per million by weight boron to the composition; and (c) at least one phosphorus ester in an amount to provide 150 to 650 parts per million by weight phosphorus to the composition, wherein the kinematic viscosity at 100° C. of the lubricant composition is less than or equal to 4.7 mm/s, provides wear resistance to a needle bearing in an automatic transmission. 1. A lubricant composition comprising:{'sup': '2', '(a) an oil having a kinematic viscosity at 100° C. of about 2.2 to about 3.7 mm/s;'}(b) at least one borate ester having an alkyl group of 4 to about 18 carbon atoms in an amount to provide about 25 to about 100, parts per million by weight boron to the composition; and(c) at least one phosphorus ester in an amount to provide about 150 to about 650 parts per million by weight phosphorus to the composition;(d) the viscosity index modifier comprise a linear polymer viscosity modifier having dispersant functionality, wherein the linear polymer has aweight average molecular weight of 5,000 to 25,000, and wherein said linear polymer is present in an amount of about 0.1 to about 4 weight percent.{'sup': '2', 'wherein the kinematic viscosity at 100° C. of the lubricant composition is less than or equal to about 4.7 mm/s.'}2. The lubricant composition of wherein:the amount of the at least one borate ester (b) is about 0.1 to about 1.1 percent by weight, or 0.15 to about 0.7 percent by weight; andthe amount of the at least one phosphorus ester (c) is about 0.05 to about 0.40 percent by weight.3. The lubricant composition of wherein the composition comprises about 100 to about 500 parts per million boron and about 150 to about 1000 parts per million phosphorus.4. The lubricant composition of wherein the oil of component (a) comprises an API Group II or ...

SINGLE PAIR ETHERNET SENSOR DEVICE AND SENSOR NETWORK

A sensor device may include an environmental sensor configured to sense an environmental parameter and generate a signal representative thereof, a single pair ethernet (SPE) interface configured to cooperate with an SPE link, and a controller provided in communication with the environmental sensor and the SPE interface. The controller may be configured to receive the signal representative of the sensed environmental parameter and to control the SPE interface to generate at least one ethernet frame including data indicative of the sensed environmental parameter for transmission over the SPE link. The controller may be further configured to automatically configure communication with a remote server over the SPE link via the SPE interface.

LIGHTING CONTROLLER, LIGHTING SYSTEM AND LIGHTING CONTROL METHOD

In a lighting system, sound levels are detected in the vicinity of at least one lighting unit to determine when there is a sound level above a threshold. The illumination provided by the lighting unit is adapted in such a way as to encourage a reduction of noise generation. 1. A controller for controlling an illumination to be provided by a lighting unit , wherein the controller is adapted to:obtain a value of a parameter of a first sound,obtain a value of the parameter of a second sound,base a reference value of the parameter on at least the value of the parameter of the second sound,determine a deviation of the value of the parameter of the first sound from the reference value of the parameter, andadjust the illumination based on the deviation,wherein the controller is further adapted to:obtain a threshold value of the parameter;compare the value of the parameter of the first sound with the threshold value of the parameter; andadjust the illumination only if the value of the parameter of the first sound is higher than the threshold value.2. The controller as claimed in claim 1 , wherein the controller is further adapted to:obtain a value of the parameter of a third sound; andbase the reference value of the parameter further on the value of the parameter of the third sound signal.3. The controller as claimed in claim 1 , wherein the controller is further adapted to:base the reference value of the parameter not on the value of the parameter of the first sound.4. The controller as claimed in claim 2 , wherein the controller is further adapted to:compare the value of the parameter of the second sound with the threshold value of the parameter;base the reference value of the parameter not on the value of the parameter of the second sound if this value is higher than the threshold value.5. (canceled)6. The controller as claimed in wherein basing the reference value of the parameter comprises determining an average value of the values of the parameter of the sound ...

MIXTURES OF FRICTION MODIFIERS TO PROVIDE GOOD FRICTION PERFORMANCE TO TRANSMISSION FLUIDS

Mixtures of friction modifiers provide excellent friction performance to transmission fluids, where the friction modifiers include an N-substituted oxalic acid bisamide or amide-ester containing at least two hydrocarbyl groups of 12 to 22 carbon atoms; and an amide or thioamide represented by RRN—C(X)Rwhere X is O or S, Rand Rare hydrocarbyl groups of at least 6 carbon atoms, and Ris hydroxyalkyl group of 1 to 6 carbon atoms or a condensate thereof. 1. A composition comprising:(a) an oil of lubricating viscosity;(b) about 0.05 to about 3.0 percent by weight of an N-substituted oxalic acid bisamide or amide-ester containing at least two hydrocarbyl groups of about 12 to about 22 carbon atoms; and{'sup': 1', '2', '3', '1', '2', '3, '(c) about 0.05 to about 3.0 percent by weight of an amide or thioamide represented by the formula RRN—C(X)Rwherein X is O or S, Rand Rare each independently hydrocarbyl groups of at least about 6 to 24 carbon atoms, and Ris hydroxyalkyl group of 1 to about 6 carbon atoms or a group formed by the condensation of said hydroxyalkyl group, through a hydroxyl group thereof, with an acylating agent.'}2. The composition of further comprising (d) about 1 to about 6 percent by weight of a dispersant component claim 1 , comprising one or more succinimide dispersants claim 1 , said dispersant component containing about 0.05 to about 1 percent by weight boron and having a TBN (oil free) of about 40 to about 100.7. The composition of wherein in (c) claim 1 , the amide or thioamide claim 1 , each of Rand Ris independently a 2-ethylhexyl group or a group of about 10 to about 18 carbon atoms.8. The composition of wherein in (c) claim 1 , the amide or thioamide claim 1 , is an amide.9. The composition of wherein (c) claim 1 , the amide or thioamide claim 1 , comprises a substituted nitrogen moiety claim 1 , RRN— claim 1 , comprising a di-cocoalkylamine moiety or a (2-ethylhexyl)(hydrogenated tallow)amine moiety and a carboxy moiety claim 1 , —C(O)R claim 1 ...

Cognition Enhancing Compounds and Compositions, Methods of Making, and Methods of Treating

The invention relates generally to muscarinic agonists, which are useful for stimulating muscarine receptors, and treating cognitive disorders. Included among the muscarinic agonists disclosed herein are oxadiazole derivatives, compositions, and preparations thereof. Methods of synthesizing oxadiazole compounds also are provided. This disclosure also relates in part to compositions for enhancing cognitive function in subjects such as humans, the compositions comprising a muscarinic agonist or a pharmaceutically suitable form thereof. This disclosure relates in part to methods of treating animals such as humans by administering such compositions. 213.-. (canceled)15150.-. (canceled) This international application claims the benefit of priority to U.S. Provisional Patent Application No. 61/403,001, filed Sep. 8, 2010, entitled “Cognition Enhancing Compounds and Compositions, Methods of Making, and Methods of Treating” The contents of which are incorporated herein by reference in their entirety.This invention was made with United States government support awarded by the following agency: National institute of Mental Health, Grant R44MH067430. The United States government has certain rights in this invention.This disclosure relates generally to muscarinic agonists, which are useful for stimulating muscarinic receptors and treating cognitive disorders. Included among the muscarinic agonists disclosed herein are oxadiazole derivatives, compositions and preparations thereof. Methods of synthesizing oxadiazole compounds also are provided. This disclosure also relates in part to compositions for enhancing cognitive function in subjects such as humans, the compositions comprising a muscarinic agonist or a pharmaceutically suitable form thereof. This disclosure relates in part to methods of treating animals such as humans by administering such compositions. Other aspects of the disclosure will become apparent to those skilled in the art.Recent research efforts have focused on ...

Gaming Machine with Integral Features for Ease of Assembly

A gaming machine includes a monitor subassembly, a game control core, and a structural frame that may be manufactured and shipped separately to a final destination and assembled on-site. The gaming machine components include integral features and components that facilitate a novel and efficient assembly process. 1. A method of assembling a gaming machine , the gaming machine including a monitor subassembly , a structural frame , and a game control core , the monitor subassembly having a free-standing position resting on a plurality of rollers , the structural frame including an integral lift mechanism and a core cavity , the method comprising:with the monitor subassembly in the free-standing position proximal to the structural frame, connecting the monitor subassembly to the lift mechanism of the structural frame;lifting the monitor assembly with the lift mechanism from the free-standing position to a mounted position supported by the structural frame; andafter the lifting, inserting at least part of the game control core into the core cavity.2. The method of claim 1 , wherein the game control core includes game-logic circuitry configured to conduct a casino wagering game and to direct an electronic display device of the monitor subassembly to display images associated with the casino wagering game claim 1 , and further comprising connecting the electronic display device to the game control core for electronic communication therebetween.3. The method of claim 2 , further comprising:receiving, at the game control core, an input from a player effecting initiation and play of the casino wagering game;initiating, by the game-logic circuitry, play of the casino wagering game responsive to the wager;directing, by the game-logic circuitry, the electronic display device to display game images representing a randomly generated outcome; andawarding the player for a winning outcome.4. The method of claim 1 , further comprising fixing the monitor subassembly to the structural ...

Lubricating Composition and Method of Lubricating a Transmission

The present invention relates to a lubricating composition comprising: (a) an oil of lubricating viscosity having a kinematic viscosity at 100° C. of 2.8 to 3.6 cSt (mm2/s) and a viscosity index of 104 to 130; (b) 1.2 to 5.0 wt % of at least one borated dispersant, wherein at least one borated dispersant is further functionalised with a sulphur or phosphorus moiety; (c) a calcium-containing detergent present in an amount to deliver at least 110 ppm to 700 ppm of calcium; (d) at least two phosphorus-containing compounds present in an amount to deliver 360 to 950 ppm of phosphorus; and (e) 0.1 wt % to 5 wt % of a linear polymer viscosity modifier having dispersant functionality. The invention further provides a method of lubricating a transmission with the lubricating composition disclosed wherein. 1. A lubricating composition comprising:{'sup': '2', '(a) an oil of lubricating viscosity having a kinematic viscosity at 100° C. of 2.8 to 3.6 cSt (mm/s) and a viscosity index of 104 to 130;'}(b) 1.2 to 5.0 wt % of at least one borated dispersant, wherein at least one borated dispersant is further functionalised with a sulphur or phosphorus moiety;(c) a calcium-containing detergent, wherein the detergent is present in an amount to deliver at least 110 ppm to 700 ppm of calcium;{'sub': '4-6', '(d) a at least two phosphorus-containing compounds, wherein the phosphorus-containing compounds are present in an amount to deliver 360 to 950 ppm of phosphorus to the lubricating composition, wherein at least 150 ppm of the phosphorus is delivered by a Chydrocarbyl phosphite; and'}(e) 0.1 wt % to 5 wt % of a linear polymer viscosity modifier having dispersant functionality, wherein the linear polymer has a weight average molecular weight of 5,000 to 25,000.2. The composition of claim 1 , wherein the calcium-containing detergent is present in an amount to deliver 130 ppm to 600 ppm of calcium.3. The composition of wherein the Chydrocarbyl phosphite is a Calkyl phosphite.4. The ...

FLOATING POWERHOUSE

Systems and methods related to floating powerhouse for hydropower turbine systems are presented. A turbine system may be coupled to floating powerhouse that can include a floating platform. A pressurized water delivery system can be coupled to the floating powerhouse and can accommodate vertical and/or horizontal movement of the floating power house. The pressurized water delivery system can include a segmented penstock coupling the turbine to an intake, and individual segments of the penstock can be free to rotate about a substantially horizontal axis, such that in response to variations in a tailwater height, the floating platform rising and falling does not disrupt fluid flow from a fluid source. 1. A turbine system , comprising:a turbine;a floating platform supporting the turbine at a tailwater level; anda pressurized water delivery system coupling a fluid flow source to the turbine, wherein the pressurized water delivery system is configured to permit vertical movement of the floating platform from a first vertical position representative of a first tailwater level to a second vertical position representative of a second tailwater level.2. The turbine system of claim 1 , wherein the pressurized water delivery system comprises:a first penstock pipe section;a second penstock pipe section; anda flexible coupling having a first mating portion connected to the first penstock pipe section and a second mating portion connected to the second penstock mating portion.3. The turbine system of claim 2 , wherein flexible coupling includes a flexible portion configured to allow the first penstock pipe section and the second penstock pipe section to be disposed at a non-zero angle to one another.4. The turbine system of claim 3 , wherein the flexible portion allows between about 1 degree and about 10 degrees of rotational movement between the first penstock pipe section and the second penstock pipe section.5. The turbine system of claim 1 , wherein the floating platform is a ...

MULTIMODAL SENSOR, METHOD OF USE AND FABRICATION

A multimodal sensor includes a microtensiometer for measuring the chemical potential of a sub-saturated liquid, a temperature sensor, and a water content sensor. The microtensiometer includes a sensor body comprising a first gas-impermeable layer, an opposing second gas-impermeable layer, and a porous membrane layer disposed therebetween. The sensor body defines an internal liquid reservoir. The membrane layer is fluidly connected with the liquid reservoir, and extends to an outside edge of the microtensiometer. The membrane layer defines a plurality of through pores providing an open path from the liquid reservoir to the outside edge of the microtensiometer. The pores have a maximum diameter of 3 millimeters. The microtensiometer further includes a sensor adapted to measure changes in pressure between the liquid reservoir and an outside environment. The temperature sensor is integrated onto the microtensiometer body, and the water content sensor is coupled to the microtensiometer body. 1. A microtensiometer , comprising:a sensor body comprising a first gas-impermeable layer and an opposing second gas-impermeable layer, the sensor body defining a sealed internal liquid reservoir;a porous membrane layer disposed between the first gas-impermeable layer and the opposing second gas-impermeable layer and in fluid contact with the sealed internal liquid reservoir, the porous membrane layer extending to an outside edge of the microtensiometer, the porous membrane layer defining a plurality of through pores, the pores providing an open path from the sealed internal liquid reservoir to the outside edge of the microtensiometer, the pores having a maximum diameter of 3 millimeters; anda sensor adapted to measure changes in pressure between the sealed internal liquid reservoir and an outside environment.2. The microtensiometer according to claim 1 , wherein the first gas-impermeable layer is formed of silicon substrate.3. The microtensiometer according to claim 1 , wherein the ...

Palm Protector Allowing Top Portions of The Hand to Remain Uncovered

A palm protector and a method for protecting the palm of the hand while allowing top portions of the hand to remain uncovered for comfort is disclosed. The palm protector is comprised of a flexible material having a grip relief and is removably-secured to the hand by means of an adhesive substrate. An object of the palm protector is to minimize injury to the palm and fingers during work or sporting activities while at the same time allowing the top of the hand to remain uncovered for proper perspiration and comfort. 1. A palm protector for protecting a palm of a hand , the palm protector comprising:a planar sheet having a palm portion, the palm portion extends to a plurality of digits;the planar sheet has a first side with a first surface exposed towards the palm of the hand and a second side with a second surface adopted to grip a tool surface;wherein the first surface has a layer of securing material to removably-affixed to the palm of the hand;wherein each of the plurality of digits of the palm portion has terminal ends that curl upwards that engages with each of the fingertips of the hand and allows the palm protector to anchor and stabilize itself to the ends of the fingers .2. The palm protector as claimed in claim 1 , wherein the second surface comprising a plurality of grip relief patterns depending upon the grip required.3. The palm protector as claimed in claim 2 , wherein the grip relief patterns include ridge patterns claim 2 , raised dot patterns claim 2 , wave patterns.4. The palm protector as claimed in claim 1 , wherein the palm protector is made of slightly sticky or an elastic material selected from rubber claim 1 , latex and silicone.5. The palm protector as claimed in claim 1 , wherein the securing material is an adhesive material selected from double coated tape claim 1 , medical grade foam claim 1 , specialty stick films claim 1 , hydrocolloids claim 1 , hydrogels claim 1 , silicone tapes claim 1 , and optically-clear tapes.6. The palm ...

LIGHT-EMITTING ACOUSTIC PANEL AND LIGHTING SYSTEM COMPRISING A SET OF SUCH PANELS

The invention relates to a set () of panels forming a lighting system, the set comprising a light-emitting panel () and a light-reflecting panel (), each panel having two opposing first sides (), two opposing second sides () and two opposing main surfaces (). Each panel is suspended from a ceiling () with a first side () thereof facing the ceiling. The light-emitting panel () comprises a light source () arranged on a second side () thereof. The second side () of the light-emitting panel () faces a main surface () of the light-reflecting panel () such that the light source () is arranged to illuminate the main surface () of the light-reflecting panel (). The invention also relates to a lighting system including such set of panels and an acoustic panel as such. 1. An acoustic panel having two opposing main surfaces , two opposing first sides and two opposing second sides , the acoustic panel further comprising:a suspending member for suspending the acoustic panel from a ceiling, the suspending member being arranged on one of the first sides such that when the acoustic panel is suspended from the ceiling the two opposing main surfaces are arranged perpendicular to the ceiling, anda light source arranged on one of the second sides such that when the acoustic panel is suspended from the ceiling the light source is arranged to provide illumination in a main direction, the main direction being parallel to the ceiling and perpendicular to the normal of the main surfaces.2. The acoustic panel according to claim 1 , wherein at least one of the main surfaces is a light-reflecting surface.3. The acoustic panel according to claim 1 , wherein the light source is a LED-based light source.4. The acoustic panel according to claim 1 , wherein the second side that is provided with the light source is further provided with a diffuser.5. The acoustic panel according to claim 4 , wherein the diffuser is a diffusing screen claim 4 , and wherein the distance (d) between the diffusing ...

Method of preparing benzyl 4-amino-3-chloro-5-fluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl)picolinate

A method of preparing benzyl 4-amino-3-chloro-5-fluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl)picolinate (I) from benzyl 4,5-difluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl)picolinate (II) is described. The method includes the use of amination and chlorination process steps to provide the compound of Formula I.

Cognition Enhancing Compounds and Compositions, Methods of Making, and Methods of Treating

The invention relates generally to muscarinic agonists, which are useful for stimulating muscarine receptors, and treating cognitive disorders. Included among the muscarinic agonists disclosed herein are oxadiazole derivatives, compositions, and preparations thereof. Methods of synthesizing oxadiazole compounds also are provided. This disclosure also relates in part to compositions for enhancing cognitive function in subjects such as humans, the compositions comprising a muscarinic agonist or a pharmaceutically suitable form thereof. This disclosure relates in part to methods of treating animals such as humans by administering such compositions. 1150.-. (canceled)152. The method of claim 151 , wherein the disorder is selected from the group consisting of presenile dementia claim 151 , senile dementia claim 151 , Parkinson's disease with dementia claim 151 , Down's syndrome claim 151 , Huntington's disease claim 151 , tardive dyskinesia claim 151 , hyperkinesia claim 151 , mania claim 151 , Tourette syndrome and Alzheimer's disease.153. A method according to claim 151 , wherein the disorder is selected from the group consisting of cognitive impairment claim 151 , Mild Cognitive Impairment claim 151 , frontotemporal dementia claim 151 , dementia with Lewy bodies claim 151 , presenile dementia claim 151 , senile dementia claim 151 , Down's syndrome claim 151 , Huntington's disease claim 151 , tardive dyskinesia claim 151 , hyperkinesia claim 151 , mania claim 151 , Tourette syndrome and Alzheimer's disease.155. The method of claim 154 , wherein the psychosis accompanies or results from schizophrenia.156. The method of claim 154 , wherein the psychosis accompanies or results from Alzheimer's disease.159. The method of claim 158 , wherein the disorder is Alzheimer's disease.161. The method of claim 160 , wherein the disorder is Alzheimer's disease.168. The method of claim 151 , wherein X is 0 claim 151 , and the disorder is Alzheimer's disease.169. The method of claim ...

BELT ATTACHMENT AND SYSTEM

Disclosed herein is a belt assembly including a flexible belt with an improved belt attachment. The belt attachment includes two crossbars spaced along the length of the belt. The crossbars retain bearings that allow predetermined movement in six degrees of freedom. The crossbars are connected by a rigid body that attaches to the bearings. Implements that are attached to the rigid body are simply supported but restrained in pitching rotation. 1. A belt assembly comprising:a flexible belt having a first surface and a second surface; a first crossbar attached to the first surface and having a first bearing, and', 'a second crossbar attached to the first surface and having a second bearing; and, 'a belt attachment further comprisinga rigid connecting body connecting the first crossbar to the second crossbar through the first bearing and the second bearing.2. The belt assembly of claim 1 , wherein one of the first bearing or the second bearing is a bushing roller bearing claim 1 , a spiral-wound bearing claim 1 , an elastomeric bearing claim 1 , or a laminated elastomeric bearing.3. The belt assembly of claim 1 , further comprising a spring element claim 1 ,wherein the spring element biases the rigid connecting body towards a predetermined location relative to the first crossbar.4. The belt assembly of claim 1 , wherein at least one of the first bearing or the second bearing is sealed from a surrounding environment.5. The belt assembly of claim 1 , wherein each crossbar comprises a plurality of bearings disposed along the length of the crossbar claim 1 , wherein a rigid connecting body connects each pair of crossbars through said plurality of bearings.6. The belt assembly of claim 1 , further comprising a separable cap component attached to each crossbar claim 1 , said cap component having a cavity that mates to a cavity in said crossbar to retain said bearing.7. The belt assembly of claim 7 , wherein the cap component and crossbar have a mating sloped face such that ...

HYDRAULIC TURBINE

Disclosed herein are linear hydraulic turbines in which the linear machine converts the majority of available energy in the flowing water into useful torque directly in the runner, leaving the outflow with very little velocity. 1. A turbine , comprising: a first segment from the second axis to the first axis, the first segment being a first stage of the turbine,', 'a second segment around the first axis,', 'a third segment from the first axis to the second axis, the third segment being a second stage of the turbine, and', 'a fourth segment around the second axis;, 'a plurality of blades configured to travel a path around a first axis and a second axis parallel to the first axis, the path comprisingwherein each of the plurality of blades have an orientation relative to a vector of blade travel resulting in a blade negative stagger angle in the first stage of the turbine, and a blade positive stagger angle in the second stage of the turbine.2. The turbine of claim 1 , wherein the first segment is substantially linear claim 1 , the second segment is substantially arc-shaped claim 1 , the third segment is substantially linear claim 1 , and the fourth segment is substantially arc-shaped.3. The turbine of claim 1 , wherein the first axis and the second axis are spaced along a horizontal plane.4. The turbine of claim 1 , wherein the first axis and the second axis are spaced along a vertical plane.5. The turbine of claim 1 , wherein each of the plurality of blades is connected at a first end to a moving structure and at a second end to a second moving structure to travel the path.6. The turbine of claim 5 , wherein the moving structure and the second moving structure are belts.7. The turbine of claim 1 , wherein each of the plurality of blades is connected to a moving structure at its mid-span claim 1 , such that ends of each blade are cantilevered.8. A turbine claim 1 , comprising:a plurality of blades attached to a structure and, traveling a path comprising a first stage ...

HYDRAULIC TURBINE

A runner for a hydraulic turbine configured to reduce fish mortality. The runner includes a hub and a plurality of blades extending from the hub. Each blade includes a root connected to the hub and a tip opposite the root. Each blade further includes a leading edge opposite a trailing edge, and a ratio of a thickness of the leading edge to a diameter of the runner can range from about 0.06 to about 0.35. Further, each blade has a leading edge that is curved relative to a radial axis of the runner. 1. A runner for a hydraulic turbine , comprising:a hub; anda plurality of blades extending from the hub,wherein each blade of the plurality of blades comprises a root located at the hub, a tip opposite the root, a leading edge, and a trailing edge opposite the leading edge, and{'sub': 't', 'wherein a ratio of a thickness of the leading edge to a diameter of the runner, tLE/D, is greater than about 0.06.'}2. The runner according to claim 1 , wherein the ratio of the thickness of the leading edge to the diameter of the runner ranges from about 0.08 to about 0.35.3. The runner according to claim 1 , wherein a maximum leading edge thickness of at least one of the blades is at least approximately 50 mm.4. The runner according to claim 1 , wherein a ratio of a maximum thickness of the runner at the blade hub to the diameter ranges from about 0.15 to about 0.25.5. The runner according to claim 1 , wherein a ratio of a maximum thickness to the diameter of the runner at the blade tip ranges from about 0.1 to about 0.25.6. The runner according to claim 1 , wherein the leading edge thickness of at least one of the blades at the blade tip is larger than the leading edge thickness at the blade root.7. The runner according to claim 1 , wherein the plurality of blades comprises five or fewer blades.8. The runner according to claim 1 , wherein the leading edge of at least one of the blades is saddle-shaped.9. The runner according to claim 1 , wherein for at least one of the blades claim 1 ...

Lubricating composition containing an ashless tbn booster

The invention provides a lubricating composition containing an oil of lubricating viscosity and a sulfurized aromatic amine compound, especially sulfur coupled aniline. The invention further relates to methods of lubricating an internal combustion engine by supplying the described lubricating composition to the internal combustion engine. The invention further relates to the use of the sulfurized aromatic amine compound as a TBN booster and an antioxidant.

AUTOMATED INTELLIGENT DATA SCRAPING AND VERIFICATION

A server computer system for parsing non-uniformly presented data from a variety of unique non-uniform third-party web portals can comprise a scripting processor configured to automatically execute a web-portal specific script for each of the one or more third-party web portals accessed by a network communication device. Each of the web-portal specific scripts can be configured to imitate inputs from a user input device and to automatically adapt interactions with each of the one or more third-party web portals to access and parse data elements from one or more non-uniformly available data fields. Further, the server computer system can comprise a database processor configured to compare a first set of data received from the one or more non-uniformly available data fields with a second set of data, which is stored within the local database device. 1. At a server computer system that intelligently loads and verifies data in a non-uniform formats against a second set of data , a computerized method for accessing and comparing non-uniformly stored data sets , the method comprising:identifying, within one or more data structures, specific data entries of interest, wherein the one or more data structures are stored within a first locally accessible database;accessing a particular third-party web portal, wherein the particular third-party web portal comprises information associated with the one or more data structures; interacting with the particular third-party web portal by imitating inputs from a user input device; and', 'automatically adapting interactions with the particular third-party web portal to access and parse data elements from one or more non-uniformly available data fields;, 'executing a particular script that is unique to the particular third-party web portal, wherein the particular script performs the method ofcomparing a first set of data received from the one or more non-uniformly available data fields with the second set of data, which is stored within ...

Lubricating composition for a hybrid electric vehicle transmission

The disclosed technology relates to a lubricant composition for use in an automatic transmission of a hybrid electric vehicle, containing an oil of lubricating viscosity, at least one borate ester, and at least one phosphorus containing compound.

METHOD AND APPARATUS FOR PREPARING CERAMIC BODY SEGMENTS

A method including providing a ceramic log () with a first end and an opposing second end; providing one or more cutting devices () comprised of a dual bladed cutting member (); and removing material by cutting at least the first end with the dual bladed cutting member (), wherein a first blade () of the dual bladed cutting member () provides a finished surface and a second blade () removes a percentage of scrap above the finished surface. An apparatus () for cutting a ceramic log (). 1. A ceramic log cutting apparatus , comprising:a nesting fixture for holding the ceramic log;one or more cutting devices, the cutting device comprised of a motor and a dual bladed cutting member;wherein a first blade of the dual bladed cutting member provides a finished surface and an off-set second blade removes a percentage of scrap above the finished surface.2. The ceramic log cutting apparatus according to claim 1 , wherein the off-set second blade has a kerf that allows for a percentage of scrap to be removed that is sufficient to prevent one or more defects proximate to an exit edge of the cut in the ceramic log.3. The ceramic log cutting apparatus according to wherein the off-set second blade provides increased structural rigidity to the first blade.4. The ceramic log cutting apparatus according to claim 1 , wherein a leading edge of a cutting surface of the off-set second blade is at least 2 mm inside that of a leading edge of a cutting surface of the first blade.5. The ceramic log cutting apparatus according to claim 1 , wherein the kerf of the off-set second blade ranges between 4 mm to 30 mm.6. The ceramic log cutting apparatus according to claim 1 , wherein a leading edge of a cutting surface of the second blade is off-set inside that of a leading edge of a cutting surface of the first blade a sufficient distance such that a sufficient amount of scrap is removed to prevent one or more defects proximate to an exit edge of the cut in the ceramic log.7. The ceramic log ...

LINEAR PELTON TURBINE

Systems and methods related to linear turbine systems are presented. Each embodiment described herein may be designed as a single-stage, linear, impulse turbine system. In an embodiment, a linear turbine includes a first shaft extending along a first axis; a second shaft extending along a second axis, the second axis being separated from and substantially parallel to the first axis; a first plurality of buckets to travel a first continuous path around the first shaft and the second shaft along a first plane, the first path including a first substantially linear path segment between the first axis and the second axis; and a nozzle configured to direct a first fluid jet to contact the first plurality of buckets in the first linear path segment. 1. A linear turbine system , comprising:a first shaft extending along a first axis;a second shaft extending along a second axis, the second axis being separated from and substantially parallel to the first axis;a plurality of buckets that travel a first continuous path around the first shaft and the second shaft along a first plane, the first path including a first substantially linear path segment between the first axis and the second axis, a first substantially arc-shaped segment around the second axis, a second substantially linear path segment between the second axis and the first axis, and a second substantially arc-shaped segment around the first axis; anda nozzle configured to direct a fluid jet to contact the plurality of buckets in the first substantially linear path segment; anda chassis having a deflection member, wherein the deflection member is arranged to divert a portion of the fluid away from the bucket after it has impinged upon the bucket.2. The linear turbine system of claim 1 , wherein the deflection member comprises a curved plate configured to direct fluid exiting the bucket away from the center portion of the linear turbine.3. The linear turbine system of claim 1 , wherein the deflection member comprises ...

ACOUSTICALLY ABSORBING ROOM DIVIDER

A room divider () for dividing a room into two sub-portions (R, R) and for attenuating sound (S, S) travelling between the two sub-portions is provided. The room divider comprises hollow cylindrical elements () arranged periodically for dividing the room into the two sub-portions. At least some of the hollow cylindrical elements have a cylindrical shell () with at least one slit () extending in an axial direction () of the shell. The shell extends continuously along the perimeter of the corresponding hollow cylindrical element from one side () of the at least one slit to another side () of the at least one slit. Each of the at least one slit faces in a local elongation direction () of the room divider for increasing acoustic symmetry with respect to the two sub-portions. The use of destructive interference and resonance to attenuate sound allows for a less bulky/heavy acoustically absorbing room divider. 1. A room divider for dividing at least a portion of a room into two sub-portions and for attenuating sound travelling between the two sub-portions , the room divider comprising a plurality of hollow cylindrical elements arranged periodically for dividing said portion of the room into said two sub-portions ,wherein each hollow cylindrical element has a cylindrical shell comprising a slit that extends in an axial direction of the cylindrical shell, the cylindrical shell extending continuously along the perimeter of the hollow cylindrical element from one side of the slit to another side of the slit, and the slit facing in a local elongation direction of the room divider, andwherein the room divider further comprises a light source arranged to emit light out of at least one of the hollow cylindrical elements.2. The room divider as defined in claim 1 , wherein the cylindrical shell is arranged to extend continuously along the two portions of the perimeter of the hollow cylindrical element facing said two sub-portions.3. The room divider as defined in claim 1 , wherein ...

LINEAR PELTON TURBINE

Systems and methods related to linear turbine systems are presented. Each embodiment described herein may be designed as a single-stage, linear, impulse turbine system. In an embodiment, a linear turbine includes a first shaft extending along a first axis; a second shaft extending along a second axis, the second axis being separated from and substantially parallel to the first axis; a first plurality of buckets to travel a first continuous path around the first shaft and the second shaft along a first plane, the first path including a first substantially linear path segment between the first axis and the second axis; and a nozzle configured to direct a first fluid jet to contact the first plurality of buckets in the first linear path segment. 1. A linear turbine system , comprising:a first shaft extending along a first axis;a second shaft extending along a second axis, the second axis being separated from and substantially parallel to the first axis;a plurality of buckets that travel a first continuous path around the first shaft and the second shaft along a first plane, the first path including a first substantially linear path segment between the first axis and the second axis, a first substantially arc-shaped segment around the second axis, a second substantially linear path segment between the second axis and the first axis, and a second substantially arc-shaped segment around the first axis; anda nozzle configured to direct a fluid jet to contact the plurality of buckets in the first substantially linear path segment; anda depower system configured to cause rapid degradation of efficiency of the turbine system at an over-speed condition.2. The linear turbine system of claim 1 , the depower system comprising:a deflector, the deflector arranged to selectively divert a portion of the fluid jet away from the bucket.3. The linear turbine system of claim 2 , wherein the deflector includes a pivot plate.4. The linear turbine system of claim 3 , wherein the pivot plate ...

TISSUE SCAFFOLD MATERIALS FOR TISSUE REGENERATION AND METHODS OF MAKING

Disclosed herein are tissue scaffold materials with microspheres of one density embedded in hydrogel of a different density. The disclosed materials have improved ability to facilitate cellular invasion and vascularization for wound healing and tissue regeneration. The inventors have found that materials having components with different densities promotes invasion of cells, including desirable cells such as fibroblasts and endothelial precursor cells, into the scaffold. 1. A tissue scaffold material comprising a hydrogel and microspheres , said hydrogel comprising a first polymer and said microspheres comprising a second polymer , wherein said microspheres are embedded in said hydrogel , and said microspheres have a greater density than said hydrogel.2. The method of claim 1 , wherein said first and second polymers are independently selected from the group consisting of collagen claim 1 , gelatin claim 1 , elastin claim 1 , hyaluronate claim 1 , cellulose claim 1 , fibrinogen claim 1 , poly(lactic-co-glycolic acid) (PLGA) claim 1 , poly(glycolic acid) (PGA) claim 1 , poly(lactic acid) (PLA) claim 1 , poly(caprolactone) claim 1 , poly(butylene succinate) claim 1 , poly(trimethylene carbonate) claim 1 , poly(p-dioxanone) claim 1 , and poly(butylene terephthalate); a polyester amide claim 1 , a polyurethane claim 1 , poly[(carboxyphenoxy) propane-sebacic acid] claim 1 , poly[bis(hydroxyethyl) terephthalate-ethyl orthophosphorylate/terephthaloyl chloride] claim 1 , a poly(ortho ester) claim 1 , a poly(alkyl cyanoacrylate) claim 1 , poly(ethylene glycol) claim 1 , a microbial polyester claim 1 , poly(β-hydroxyalkanoate) claim 1 , and a tyrosine derived polycarbonate.3. The method of claim 2 , wherein said second polymer is collagen.4. The method of claim 2 , wherein said first polymer is collagen.5. The tissue scaffold material of claim 1 , wherein the microspheres are comprised of 0.2% to 2.0% w/v of said second polymer.6. The tissue scaffold material of claim 5 , ...

BELT ATTACHMENT AND SYSTEM

Disclosed herein is a belt assembly including a flexible belt with an improved belt attachment. The belt attachment includes two crossbars spaced along the length of the belt. The crossbars retain bearings that allow predetermined movement in six degrees of freedom. The crossbars are connected by a rigid body that attaches to the bearings. Implements that are attached to the rigid body are simply supported but restrained in pitching rotation. 1. A belt assembly comprising:a flexible belt having a first surface and a second surface;a belt attachment further comprising:a first crossbar attached to the first surface and having a first bearing, anda second crossbar attached to the first surface and having a second bearing; anda rigid connecting body connecting the first crossbar to the second crossbar through the first bearing and the second bearing.2. The belt assembly of claim 1 , wherein one of the first bearing or the second bearing is a bushing roller bearing claim 1 , a spiral-wound bearing claim 1 , an elastomeric bearing claim 1 , or a laminated elastomeric bearing.3. The belt assembly of claim 1 , further comprising a spring element claim 1 , wherein the spring element biases the rigid connecting body towards a predetermined location relative to the first crossbar.4. The belt assembly of claim 1 , wherein at least one of the first bearing or the second bearing is sealed from a surrounding environment.5. The belt assembly of claim 1 , wherein each crossbar comprises a plurality of bearings disposed along the length of the crossbar claim 1 , wherein a rigid connecting body connects each pair of crossbars through said plurality of bearings.6. The belt assembly of claim 1 , further comprising a separable cap component attached to each crossbar claim 1 , said cap component having a cavity that mates to a cavity in said crossbar to retain said bearing.7. The belt assembly of claim 6 , wherein the cap component and crossbar have a mating sloped face such that the ...

WEDGE CLAMPING SYSTEM FOR BEAMS

A wedge clamp comprises a wedge with an inclined face and an endplate with a pocket that has a mating inclined face. A beam has a curved clamping surface that engages the wedge and a lower surface that engages the endplate. The beam is clamped in the endplate by preloading the wedge into the endplate pocket. 1. A wedge clamp , comprising: a first inclined wedge face and a second wedge face, each being located between a wedge forward end and a wedge rearward end; and', 'an endplate including:, 'a wedge includinga pocket having a pocket upper inclined face and a pocket lower face between a pocket open end and a pocket rearward end,wherein the wedge and endplate engage a beam including a beam front face, a beam end face, a beam curved horizontal upper surface, and a beam lower surface, the beam lower surface being arranged to partially engage the endplate at its lower face,wherein the curved upper surface engages the second wedge face,wherein the wedge is preloaded in the pocket between the pocket upper inclined face and the beam curved horizontal upper surface.2. The wedge clamp of claim 1 , further comprising:a plug configured to occupy an interior space in the beam along a beam length corresponding to a clamping distance.3. The wedge clamp of claim 1 , wherein the wedge is preloaded by a press claim 1 , clamp claim 1 , or fastener.4. The wedge clamp of claim 3 , wherein the fastener is left in place after preloading and remains an integral portion of the wedge clamp.5. The wedge clamp of claim 1 , wherein the wedge is made from a compliant material.6. The wedge clamp of claim 1 , wherein the wedge is made from a rigid material.7. The wedge clamp of claim 1 , wherein the wedge has a variable modulus of elasticity.8. A wedge clamp system comprising: a first inclined wedge face and a second wedge face, each being located between a wedge forward end and a wedge rearward end; and', 'an endplate including:', 'a pocket having a pocket upper inclined face and a pocket lower ...

MIXED PHOSPHORUS ESTERS FOR LUBRICANT APPLICATIONS

A lubricant composition of an oil of lubricating viscosity and a phosphite ester reaction product of a monomeric phosphorous acid or an ester thereof with a first alkylene diol having two hydroxy groups in a 1,4 or 1,5 or 1,6 relationship and a second, alkyl-substituted, diol being a substituted 1,3-propylene diol, exhibits good wear and frictional performance. 1. A lubricant composition comprising an oil of lubricating viscosity and a phosphite ester composition (A) , other than a zinc salt , which comprises the reaction product of(a) a monomeric phosphorous acid or an ester thereof with(b) at least two alkylene diols:a first alkylene diol (i) having two hydroxy groups in a 1,4 or 1,5 or 1,6 relationship;a second alkylene diol (ii) being an alkyl-substituted 1,3-propylene diol with one or more of the alkyl substituents thereof being on one or more of the carbon atoms of the propylene unit, the total number of carbon atoms in the alkyl-substituted 1,3-propylene diol being about 5 to about 12;wherein the relative molar amounts of monomeric phosphorous acid or ester thereof (a) and the total of the alkylene diols (b) are in a ratio of about 0.9:1.1 to about 1.1:0.9;wherein the relative molar amounts of the first alkylene diol (i) and the alkyl-substituted 1,3-propylene diol (ii) are in a ratio of about 30:70 to about 65:35; anda grease thickener.2. The lubricant composition of wherein the amount of the phosphite ester composition is about 0.001 to about 10 weight percent of the lubricant composition.3. The lubricant composition of wherein monomeric phosphorous ester comprises dimethyl phosphite.4. The lubricant composition of wherein the first alkylene diol comprises 1 claim 1 ,4-butanediol claim 1 , 1 claim 1 ,5-pentanediol claim 1 , or 1 claim 1 ,6-hexanediol.5. The lubricant composition of wherein the second alkylene diol comprises 2-ethyl-2-butylpropane-1 claim 1 ,3-diol claim 1 , 2-ethylhexane-1 claim 1 ,3-diol claim 1 , 2 claim 1 ,2-dibutylpropane-1 claim 1 ,3- ...

Tissue scaffold materials for tissue regeneration and methods of making

Disclosed herein are tissue scaffold materials with microspheres of one density embedded in hydrogel of a different density. The disclosed materials have improved ability to facilitate cellular invasion and vascularization for wound healing and tissue regeneration. The inventors have found that materials having components with different densities promotes invasion of cells, including desirable cells such as fibroblasts and endothelial precursor cells, into the scaffold.

NITROGEN-FREE PHOSPHORUS COMPOUNDS AND LUBRICANTS CONTAINING THE SAME

A composition obtained by reacting an O,O′-dialkyldithiophosphoric acid with a hydroxyalkyl acrylate or a hydroxyalkyl methacrylate, and reacting the product thereof with a dialkylphosphite provides good antiwear protection. 3. The composition of wherein Rand Rare 2-ethylhexyl groups or 4-methyl-2-pentyl groups or mixtures thereof.4. A composition obtained or obtainable by reacting(a) an O,O′-dialkyldithiophosphoric acid with(b) a hydroxyalkyl acrylate or a hydroxyalkyl methacrylate, and reacting the product thereof with(c) a dialkylphosphite.5. The composition of obtained or obtainable by reacting(a) an O,O-dialkyldithiophosphoric acid with(b) a hydroxyalkyl acrylate or a hydroxyalkyl methacrylate, and reacting the product thereof with(c) a dialkylphosphite.6. The composition of wherein the components (a) claim 4 , (b) claim 4 , and (c) are reacted in a molar ratio of about 2:2:1.7. The composition of wherein the alkyl groups of (a) the O claim 4 ,O-dialkyldithiophosphoric acid each are independently Cto Calkyl groups.8. The composition of wherein the alkyl groups of (a) are each independently Cor Calkyl groups.9. The composition of wherein the alkyl groups of (a) are 2-ethylhexyl groups or 4-methyl-2-pentyl groups or mixtures thereof.10. The composition of wherein (b) the hydroxyalkyl acrylate or hydroxyalkyl methacrylate comprises a hydroxyalkyl acrylate.11. The composition of wherein the hydroxyalkyl group of (b) is a 2-hydroxyethyl group.12. The composition of wherein the dialkylphosphite comprises alkyl groups of claim 4 , independently claim 4 , 1 to about 12 carbon atoms.13. The composition of wherein the dialkylphosphite comprises dimethylphosphite.14. The composition of wherein the O claim 4 ,O-dialkyldithiophosphoric acid of (a) is added to the hydroxyalkyl acrylate or -methacrylate of (b) and reacted at about 40 to about 80° C. claim 4 , and the dialkylphosphite of (c) is added thereto claim 4 , optionally in the presence of base claim 4 , with heating ...

ENGINE LUBRICANTS FOR SILOXANE DEPOSIT CONTROL

A zinc free or substantially zinc free lubricant having a sulfated ash content of less than about 1.0 percent and including (a) an oil of lubricating viscosity; (b) 0.03 to about 3.0 weight percent of a phosphite compound; (c) an metal containing detergent; (d) a polyisobutylene succinimide dispersant derived from an ethylene polyamine and having a carbonyl to nitrogen ratio equal or greater than 1; (e) at least one other dispersant; (f) a boron containing compound in amount to provide at least 25 ppm boron to the lubricant composition is useful for inhibiting siloxane deposits in a stationary gas engine fueled by natural gas having a high silicon concentration. 1. A method for lubricating a natural gas fueled , sump-lubricated , stationary gas engine comprising supplying to the engine a lubricant composition comprising:(a) an oil of lubricating viscosity;(b) 0.03 to about 3.0 weight percent with respect to the lubricant of a phosphite compound;(c) a metal containing detergent;(d) at least a first dispersant, wherein the first dispersant is a polyisobutylene succinimide dispersant derived from an ethylene polyamine and having a carbonyl to nitrogen ratio equal or greater than 1;(e) at least one other dispersant selected from the group consisting of a succinimide dispersant having a carbonyl to nitrogen ratio less than 1, a Mannich dispersant, a succinamide dispersant, and a polyisobutylene succinic acid ester dispersant;a boron containing compound in amount to provide at least 25 ppm boron to the lubricant composition;wherein the lubricant composition is free or substantially free of zinc, andwherein the lubricant composition has a sulfated ash content of less than about 1.0 wt. %.2. The method of wherein the phosphite compound comprises a phosphite ester selected from the group consisting of phosphite diesters claim 1 , phosphite triesters and mixtures thereof.4. The method of wherein the phosphite compound comprises a phosphite diester having ester groups of 2 to ...

Compounds and Compositions for Cognition-Enhancement, Methods of Making, and Methods of Treating

Disclosed are muscarinic agonist compounds including oxadiazole derivatives, compositions and preparations thereof. Also disclosed are methods of synthesizing such oxadiazole compounds. Further disclosed are methods for treating a subject with said muscarinic agonists or a pharmaceutically suitable form thereof to enhance cognitive function.

HYDRAULIC TURBINE

Disclosed herein are linear hydraulic turbines in which the linear machine converts the majority of available energy in the flowing water into useful torque directly in the runner, leaving the outflow with very little velocity. 1. A turbine , comprising: a first segment from the second axis to the first axis, the first segment being a first stage of the turbine,', 'a second segment around the first axis,', 'a third segment from the first axis to the second axis, the third segment being a second stage of the turbine, and', 'a fourth segment around the second axis;, 'a plurality of blades configured to travel a path around a first axis and a second axis parallel to the first axis, the path comprisingwherein each of the plurality of blades have an orientation relative to a vector of blade travel resulting in a blade negative stagger angle in the first stage of the turbine, and a blade positive stagger angle in the second stage of the turbine.2. The turbine of claim 1 , wherein the first segment is substantially linear claim 1 , the second segment is substantially arc-shaped claim 1 , the third segment is substantially linear claim 1 , and the fourth segment is substantially arc-shaped.3. The turbine of claim 1 , wherein the first axis and the second axis are spaced along a horizontal plane.4. The turbine of claim 1 , wherein the first axis and the second axis are spaced along a vertical plane.5. The turbine of claim 1 , wherein each of the plurality of blades is connected at a first end to a moving structure and at a second end to a second moving structure to travel the path.6. The turbine of claim 5 , wherein the moving structure and the second moving structure are belts.7. The turbine of claim 1 , wherein each of the plurality of blades is connected to a moving structure at its mid-span claim 1 , such that ends of each blade are cantilevered.8. A turbine claim 1 , comprising:a plurality of blades attached to a structure and , traveling a path comprising a first stage ...

RECOVERY AND/OR REUSE OF PALLADIUM CATALYST AFTER A SUZUKI COUPLING

Methods for the recovery and/or reuse of palladium catalyst after a Suzuki coupling reaction in which two molecules are coupled are described. 2. The method of claim 1 , wherein greater than 70% of the palladium catalyst used in the first Suzuki coupling reaction is recovered.3. The method of claim 1 , wherein the palladium catalyst is formed from palladium acetate or palladium chloride.4. The method of claim 1 , wherein the substituted boronic acid is (4-chloro-2-fluoro-3-methoxyphenyl)boronic acid.5. The method of claim 1 , wherein Ris H.6. The method of claim 1 , wherein the compound of Formula (II) is chlorinated.7. The method of claim 1 , wherein the compound of Formula (II) is 4 claim 1 ,5 claim 1 ,6-trichloropicolinic acid or 5 claim 1 ,6-dichloropicolinic acid.8. The method of claim 1 , wherein the ligand is triphenylphosphine or dppf.9. The method of claim 1 , wherein the Suzuki coupling reaction is done in a solvent system comprising a miscible polar aprotic solvent and water.10. The method of claim 9 , wherein the miscible polar aprotic solvent is acetonitrile.11. The method of claim 1 , wherein the base is triethylamine.12. The method of claim 1 , wherein Ris C-Calkyl or C-Carylalkyl and the product of step A) is hydrolyzed prior to performing step B).13. The method of claim 1 , wherein the palladium is recovered with other solvents and reactants from the first Suzuki coupling reaction and the combination of palladium with the other solvents and reactants from the first Suzuki coupling reaction is added to the second Suzuki coupling reaction.14. The method of claim 13 , wherein some solvents are removed prior to addition to the second Suzuki coupling reaction.15. The method of claim 13 , wherein the palladium is isolated from the other solvents and reactants prior to addition to the second Suzuki coupling reaction.16. The method of claim 1 , wherein an acid is added to the first Suzuki coupling reaction product to form a mother liquor and a precipitate. ...

Cognition Enhancing Compounds and Compositions, Methods of Making, and Methods of Treating

The invention relates generally to muscarinic agonists, which are useful for stimulating muscarine receptors, and treating cognitive disorders. Included among the muscarinic agonists disclosed herein are oxadiazole derivatives, compositions, and preparations thereof. Methods of synthesizing oxadiazole compounds also are provided. This disclosure also relates in part to compositions for enhancing cognitive function in subjects such as humans, the compositions comprising a muscarinic agonist or a pharmaceutically suitable form thereof. This disclosure relates in part to methods of treating animals such as humans by administering such compositions. 213.-. (canceled)15150.-. (canceled) This international application claims the benefit of priority to U.S. Provisional Patent Application No. 61/403,001, filed Sep. 8, 2010, entitled “Cognition Enhancing Compounds and Compositions, Methods of Making, and Methods of Treating” The contents of which are incorporated herein by reference in their entirety.This invention was made with United States government support awarded by the following agency: National Institute of Mental Health, Grant R44MH067430. The United States government has certain rights in this invention.This disclosure relates generally to muscarinic agonists, which are useful for stimulating muscarinic receptors and treating cognitive disorders. Included among the muscarinic agonists disclosed herein are oxadiazole derivatives, compositions and preparations thereof. Methods of synthesizing oxadiazole compounds also are provided. This disclosure also relates in part to compositions for enhancing cognitive function in subjects such as humans, the compositions comprising a muscarinic agonist or a pharmaceutically suitable form thereof. This disclosure relates in part to methods of treating animals such as humans by administering such compositions. Other aspects of the disclosure will become apparent to those skilled in the art.Recent research efforts have focused on ...

MIXED PHOSPHORUS ESTERS FOR LUBRICANT APPLICATIONS

A lubricant composition of an oil of lubricating viscosity and a phosphite ester reaction product of a monomeric phosphorous acid or an ester thereof with a first alkylene diol having two hydroxy groups in a 1,4 or 1,5 or 1,6 relationship and a second, alkyl-substituted, diol being a substituted 1,3-propylene diol, exhibits good wear and frictional performance. 1. A lubricant composition comprising an oil of lubricating viscosity and a phosphite ester composition (A) , other than a zinc salt , which comprises the reaction product of(a) a monomeric phosphorous acid or an ester thereof with(b) at least two alkylene diols:a first alkylene diol (i) having two hydroxy groups in a 1,4 or 1,5 or 1,6 relationship;a second alkylene diol (ii) being an alkyl-substituted 1,3-propylene diol with one or more of the alkyl substituents thereof being on one or more of the carbon atoms of the propylene unit, the total number of carbon atoms in the alkyl-substituted 1,3-propylene diol being about 5 to about 12;wherein the relative molar amounts of monomeric phosphorous acid or ester thereof (a) and the total of the alkylene diols (b) are in a ratio of about 0.9:1.1 to about 1.1:0.9; andwherein the relative molar amounts of the first alkylene diol (i) and the alkyl-substituted 1,3-propylene diol (ii) are in a ratio of about 30:70 to about 65:35.2. The lubricant composition of wherein the amount of the phosphite ester composition is about 0.05 or 0.06 to about 2.0 weight percent of the lubricant composition.3. The lubricant composition of wherein monomeric phosphorous ester comprises dimethyl phosphite.4. The lubricant composition of wherein the first alkylene diol comprises 1 claim 1 ,4-butanediol claim 1 , 1 claim 1 ,5-pentanediol claim 1 , or 1 claim 1 ,6-hexanediol.5. The lubricant composition of wherein the second alkylene diol comprises 2-ethyl-2-butylpropane-1 claim 1 ,3-diol claim 1 , 2-ethylhexane-1 claim 1 ,3-diol claim 1 , 2 claim 1 ,2-dibutylpropane-1 claim 1 ,3-diol claim 1 ...

Belt Attachment and System

Disclosed herein is a belt assembly including a flexible belt with an improved belt attachment. The belt attachment includes two crossbars spaced along the length of the belt. The crossbars retain bearings that allow predetermined movement in six degrees of freedom. The crossbars are connected by a rigid body that attaches to the bearings. Implements that are attached to the rigid body are simply supported but restrained in pitching rotation,

PORTABLE AND TRACKABLE SECURITY BOX AND METHOD FOR DELIVERING AND TRACKING SECURITY BOX

A shipping box system and method are provided in which a shipping box has a container having a bottom surface and a plurality of walls, the container walls forming a perimeter about a container cavity. The shipping box further has a lid having a top surface and walls, the lid walls forming a perimeter about a lid cavity. The box further provides a sensor module for determining a physical location and orientation of the container, a computations module for evaluating data retrieved from the sensor module, and a locking assembly for locking the container and the lid in a closed configuration. The container and the lid are sized to nest, such that when the lid is fixed to the container, the container cavity and the lid cavity occupy substantially the same space and the container walls and the lid walls overlap. 1. A shipping box system comprising a first shipping box having:a container having a bottom surface and a plurality of container walls extending from the bottom surface, the container walls forming a perimeter about a container cavity;a lid having a top surface and a plurality of lid walls extending from the top surface, the lid walls forming a perimeter about a lid cavity;a sensor module for determining a physical location and orientation of the container;a computations module for evaluating data retrieved from the sensor module;a locking assembly for locking the container and the lid in a closed configuration;wherein the container and the lid are sized to nest, such that when the lid is fixed to the container, the container cavity and the lid cavity occupy substantially the same space and the container walls and the lid walls overlap.2. The shipping box system of claim 1 , wherein the perimeter about the lid cavity is larger than the perimeter about the container cavity claim 1 , such that the container is nested within the lid claim 1 , and wherein the container walls and the lid walls have substantially similar heights claim 1 , such that the container is ...

HYDRAULIC TURBINE

A runner for a hydraulic turbine configured to reduce fish mortality. The runner includes a hub and a plurality of blades extending from the hub. Each blade includes a root connected to the hub and a tip opposite the root. Each blade further includes a leading edge opposite a trailing edge, and a ratio of a thickness of the leading edge to a diameter of the runner can range from about 0.06 to about 0.35. Further, each blade has a leading edge that is curved relative to a radial axis of the runner. 1. A runner for a hydraulic turbine , comprising:a hub; anda plurality of blades extending from the hub,wherein each blade of the plurality of blades comprises a root located at the hub, a tip opposite the root, a leading edge, and a trailing edge opposite the leading edge, and{'sub': LE', 't, 'wherein a ratio of a thickness of the leading edge to a diameter of the runner, t/D, is greater than about 0.06.'}2. The runner according to claim 1 , wherein the ratio of the thickness of the leading edge to the diameter of the runner ranges from about 0.08 to about 0.35.3. The runner according to claim 1 , wherein a maximum leading edge thickness of at least one of the blades is at least approximately 50 mm.4. The runner according to claim 1 , wherein a ratio of a maximum thickness of the runner at the blade hub to the diameter ranges from about 0.15 to about 0.25.5. The runner according to claim 1 , wherein a ratio of a maximum thickness to the diameter of the runner at the blade tip ranges from about 0.1 to about 0.25.6. The runner according to claim 1 , wherein the leading edge thickness of at least one of the blades at the blade tip is larger than the leading edge thickness at the blade root.7. The runner according to claim 1 , wherein the plurality of blades comprises five or fewer blades.8. The runner according to claim 1 , wherein the leading edge of at least one of the blades is saddle-shaped.9. The runner according to claim 1 , wherein for at least one of the blades claim ...

Additive compositions for lubricants and functional fluids

This invention relates to a composition, comprising: (A) a compound represented by the formula ##STR1## wherein in Formula (A-I), G 1 and G 2 are independently R, OR, SR or NRR wherein each R is independently a hydrocarbyl group, X 1 and X 2 are independently O or S, and n is zero to 3; and (B) an acylated nitrogen-containing compound having a substituent of at least 10 aliphatic carbon atoms. In one embodiment, the inventive composition further comprises (C) a phosphorus compound. In one embodiment, the inventive composition further comprises (D) an alkali or alkaline earth metal salt of an organic sulfur acid, carboxylic acid or phenol. In one embodiment, the inventive composition further comprises (E) a thiocarbamate. These compositions are useful in providing lubricating compositions and functional fluids with enhanced antiwear properties.

Fuel compositions containing N-substituted perhydro-s-triazines

Process and apparatus for making aqueous hydrocarbon fuel compositions, and aqueous hydrocarbon fuel composition

This invention relates to a process for making an aqueous hydrocarbon fuel composition, comprising: (A) mixing a normally liquid hydrocarbon fuel and at least one chemical additive to form a hydrocarbon fuel-additive mixture; and (B) mixing said hydrocarbon fuel-additive mixture with water under high shear mixing conditions in a high shear mixer to form said aqueous hydrocarbon fuel composition, said aqueous hydrocarbon fuel composition including a discontinuous aqueous phase, said discontinuous aqueous phase being comprised of aqueous droplets having a mean diameter of 1.0 micron or less. An apparatus for operating the foregoing process is also disclosed. Aqueous hydrocarbon fuel compositions are disclosed.

Process and apparatus for making aqueous hydrocarbon fuel compositions, and aqueous hydrocarbon fuel compositions

This invention relates to a process for making an aqueous hydrocarbon fuel composition, comprising: (A) mixing a normally liquid hydrocarbon fuel and at least one chemical additive to form a hydrocarbon fuel-additive mixture; and (B) mixing said hydrocarbon fuel-additive mixture with water under high shear mixing conditions in a high shear mixer to form said aqueous hydrocarbon fuel composition, said aqueous hydrocarbon fuel composition including a discontinuous aqueous phase, said discontinuous aqueous phase being comprised of aqueous droplets having a mean diameter of 1.0 micron or less. An apparatus for operating the foregoing process is also disclosed. Aqueous hydrocarbon fuel compositions are disclosed.

Zeolite L catalyst for reforming

An improved reforming catalyst employing a zeolite L support is provided by soaking the zeolite L in an alkali solution having a pH of at least 11 for a time and at a temperature effective to increase the period of time over which the catalytic activity of the catalyst is maintained.

Method using titanium compounds and complexes as additives in lubricants

Improved synthesis of 6-aryl-4-aminopicolinates

The present disclosure relates to improved methods of synthesizing 6-aryl-4-aminopicolinates, such as arylalkyl and alkyl 4-amino-3-chloro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylates.

Laminar mixing apparatus and methods

Lubricating composition containing an ester

The invention relates to a method of lubricating a limited slip differential comprising supplying to the limited slip differential a lubricating composition containing (a) an oil of lubricating viscosity, and (b) a C4-30-diester of a dicarboxylic acid. The invention further provides for the use of the C4-30-diester of a dicarboxylic acid as a friction modifier, typically in a limited slip differential.

Zeolite l catalyst for reforming

ABSTRACT OF THE DISCLOSURE An improved reforming catalyst employing a zeolite support is provided by soaking a zeolite L in an alkali solution having a pH of at least 11 for a time and at a temperature effective to increase the period of time over which the catalytic activity of the catalyst is maintained.

Hydroxy-containing tertiary amines as friction modifiers for automatic transmission fluids

A composition of a major amount of an oil of lubricating viscosity; a secondary or tertiary amine being represented by the formula R1R2NR3 wherein R1 and R2 are alkyl groups of at least 6 carbon atoms and R3 is hydrogen, a hydrocarbyl group, a hydroxyl-containing alkyl group, or an amine-containing alkyl group; and a dispersant, provides high static coefficients of friction and a durable positive slope during oxidative and mechanical stressing, particularly as a friction component of an automatic transmission.

Hydroxy-containing tertiary amines as friction modifiers for automatic transmission fluids

A composition of a major amount of an oil of lubricating viscosity; a secondary or tertiary amine being represented by the formula R1R2NR3 wherein R1 and R2 are alkyl groups of at least 6 carbon atoms and R3 is hydrogen, a hydrocarbyl group, a hydroxyl-containing alkyl group, or an amine-containing alkyl group; and a dispersant, provides high static coefficients of friction and a durable positive slope during oxidative and mechanical stressing, particularly as a friction component of an automatic transmission.

Method of preparing benzy 4-amino-3-chloro-5-fluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl)picolinate

A method of preparing benzyl 4-amino-3-chloro-5-fluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl)picolinate (I) from benzyl 4,5-difluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl)picolinate (II) is described. The method includes the use of amination and chlorination process steps to provide the compound of Formula I.

Lubricant composition comprising anti-foam agents

The disclosed invention relates to a multigrade lubricant composition which can be used for numerous lubricant applications, but is particularly useful for lubricating a diesel engine. The lubricant composition comprises an oil of lubricating viscosity, a detergent, a dispersant, a viscosity index improver, and a combination of anti-foam agents. The lubricant composition may be used for providing enhanced fuel economy and avoiding air entrainment problems when used in lubricating diesel engines.

Tissue scaffold materials for tissue regeneration and methods of making

Disclosed herein are tissue scaffold materials with microspheres of one density embedded in hydrogel of a different density. The disclosed materials have improved ability to facilitate cellular invasion and vascularization for wound healing and tissue regeneration. The inventors have found that materials having components with different densities promotes invasion of cells, including desirable cells such as fibroblasts and endothelial precursor cells, into the scaffold.

Intratracheal tube

Hydroxy-containing tertiary amines as friction modifiers for automatic transmission fluids

A composition of a major amount of an oil of lubricating viscosity; a secondary or tertiary amine being represented by the formula R1R2NR3 wherein R1 and R2 are alkyl groups of at least 6 carbon atoms and R3 is hydrogen, a hydrocarbyl group, a hydroxyl-containing alkyl group, or an amine-containing alkyl group; and a dispersant, provides high static coefficients of friction and a durable positive slope during oxidative and mechanical stressing, particularly as a friction component of an automatic transmission.

Preparation of compounds having pesticidal activity

A method of forming a compound of formula (I) as described herein is provided. Some embodiments of the compound of formula (I) are known to have herbicidal activity. The method comprises combining a compound of formula (II) and a compound of formula (IIIa) or (IIIb), each as described herein, or a salt or ester thereof in a liquid mixture comprising the compounds of formula (II), formula (IIIa) or (IIIb), water, a non-aqueous solvent, a surfactant, a catalyst, and a ligand at certain temperature, pH, and HLB ranges to form a chemical reaction product mixture comprising the compound of formula (I) and by-products.

Farm tractor lubricating composition with good water tolerance

A lubricant of (a) an oil of lubricating viscosity; (b) a block copolymer of (i) a hydrophobic first block of C1-30 alkyl (meth)acrylic units having an average total number of carbon atoms of at least 8, and (n) a second block of (meth)acrylic units, at least some units of which comprise a heteroatom imparting polar character to the block, (c) an overbased calcium detergent, (d) a phosphorus-containing anti-wear agent that does not contribute to the metal content of the lubricant, and (e) a friction modifier suitable to reduce the static coefficient of friction at a metal-composition interface, is suitable for lubricating a farm tractor

Molybdenum-containing lubricant for improved power or fuel economy

Additive formulation for lubricating oils

Lubricating oils containing an additive formulation including at least one sulphonate, saligenin and salixarate detergent provide improved wear performance and decreased sulphur and phosphorus emissions.

Method of lubricating a tractor hydraulic

The present invention relates to a method of lubricating a tractor with a lubricating composition containing: an oil of lubricating viscosity and a sulphur-free phosphorus-containing salt of either (i) a hydroxy-substituted di-ester of phosphoric acid, or (ii) a phosphorylated hydroxy-substituted di- or tri-ester of phosphoric acid.

Dispersant combination for improved transmission fluids

A lubricant composition of an oil, a dispersant viscosity modifier of a poly(meth)acrylate copolymer having a nitrogen-containing monomer in an amount to provide at least about 0.4 percent by weight nitrogen to the copolymer, and a succinimide dispersant prepared in the substantial absence of chlorine gives good performance as a transmission fluid.

Lubricating oil composition

This invention relates to a lubricating oil composition, comprising: (A) a base oil; and a phosphorus-containing compound represented by the formulae wherein in Formulae (B-I) and (B-II), R 1 , R 2 and R 3 are independently hydrogen or hydrocarbyl groups, and a, b and c are independently zero or 1; the lubricating oil composition being characterized by a sulfur content of about 0.01 to about 0.25% by weight.

Mixtures of friction modifiers to provide good friction performance to transmission fluids

PROTECTED SEALING DEVICE AND PROTECTIVE FILTERS

Belt attachment and system

Disclosed herein is a belt assembly including a flexible belt with an improved belt attachment. The belt attachment includes two crossbars spaced along the length of the belt. The crossbars retain bearings that allow predetermined movement in six degrees of freedom. The crossbars are connected by a rigid body that attaches to the bearings. Implements that are attached to the rigid body are simply supported but restrained in pitching rotation.

Additive compositions for lubricants and functional fluids

Process for separating one or more aliphatic diamines from reductive amination reaction solvents and impurities

The instant invention provides a process for separating one or more aliphatic diamines from reductive amination reaction solvents and impurities, and aliphatic diamines obtained via such a process. The process for separating one or more aliphatic diamines from reductive amination reaction solvents and impurities according to the instant invention comprises the steps of: (1) feeding one or more cycloaliphatic cyanoaldehydes, hydrogen, ammonia, and optionally one or more solvents into a continuous reductive amination reactor system; (2) contacting said one or more cycloaliphatic cyanoaldehydes, hydrogen, and ammonia with each other in the presence of one or more heterogeneous metal based catalyst systems at a temperature in the range of from 80° C. to about 160° C. and a pressure in the range of from 700 to 3500 psig; (3) thereby forming a product mixture comprising one or more cycloaliphatic diamines, optionally one or more bicyclic by-products, optionally one or more cycloaliphatic aminonitriles, optionally one or more cycloaliphatic aminoalcohols, optionally one or more oligomeric by-products, ammonia, water, hydrogen, and optionally one or more solvents; (4) removing said product mixture from the reactor system; (5) removing at least a portion of said ammonia, said hydrogen, or mixture thereof from said product mixture via distillation; (6) removing at least a portion of said water and said one or more optional solvents via distillation; (7) removing at least a portion of one or more optional bicyclic by-products via distillation; (8) removing one or more optional cycloaliphatic aminonitriles, one or more optional cycloaliphatic aminoalcohols, one or more optional oligomeric by-products via distillation; and (9) thereby separating said one or more cycloaliphatic diamines from said product mixture.

Lubricating oil compositions containing saligenin derivatives

A saligenin derivative such as the magnesium salt represented by the formula is useful as an additive for a lubricating composition. Preferably X is —CHO or —CH 2 OH, and Y is —CH 2 — or —CH 2 OCH 2 —. R 1 is a hydrocarbyl group containing 1 to 60 carbon atoms and m is 0 to 10. At least one aromatic ring should contain an R 1 substituent and the total number of carbon atoms in all R 1 groups should be at least 7.

Linear pelton turbine

Systems and methods related to linear turbine systems are presented. Each embodiment described herein may be designed as a single-stage, linear, impulse turbine system. In an embodiment, a linear turbine includes a first shaft extending along a first axis; a second shaft extending along a second axis, the second axis being separated from and substantially parallel to the first axis; a first plurality of buckets to travel a first continuous path around the first shaft and the second shaft along a first plane, the first path including a first substantially linear path segment between the first axis and the second axis; and a nozzle configured to direct a first fluid jet to contact the first plurality of buckets in the first linear path segment.

Mixed phosphorus esters for lubricant applications

A lubricant composition of an oil of lubricating viscosity and a phosphite ester reaction product of a monomeric phosphorous acid or an ester thereof with a first alkylene diol having two hydroxy groups in a 1,4 or 1,5 or 1,6 relationship and a second, alkyl-substituted, diol being a substituted 1,3-propylene diol, exhibits good wear and frictional performance.

Farm tractor lubricating composition with good water tolerance

A lubricant of (a) an oil of lubricating viscosity; (b) a block copolymer of (i) a hydrophobic first block of C

Microtensiometer

A microtensiometer is provided that includes a substrate layer having an enclosed reservoir formed therein. A porous membrane is disposed on a surface of the substrate layer. The membrane includes a liquid side fluidly coupled to the reservoir and a vapor side fluidly coupled to a vapor interface. The porous membrane includes a plurality of through holes fluidly coupling the liquid reservoir to the vapor interface, and a nanoporous filler material disposed within the plurality of through holes. The filler material includes a plurality of open pores having a maximum diameter in the range of 0.2 to 200 nanometers. In one embodiment, the microtensiometer includes a molecular membrane disposed adjacent to the vapor side of the porous membrane. In one example, the molecular membrane is a highly crystalline polytetrafluoroethylene polymer having a microstructure characterized by nodes interconnected by fibrils. In one application, the microtensiometer may be used to measure the average water potential within a network of plant or tree xylem. In another application, the microtensiometer may be useful in real-time determination of the water potential in soil.

Cup shape machine

Process and apparatus for making aqueous hydrocarbon fuel compositions, and aqueous hydrocarbon fuel compositions

Multi-Dispersant Lubricating Composition

The present invention relates to a lubricating composition containing a corrosion inhibitor compound and a mixture of two or more dispersants, wherein 0 mole % to less than 50 mole % of the second dispersant molecules contain a carbocyclic ring. The invention further provides a method for lubricating a mechanical device using the lubricating composition.

Grooming tool

A grooming tool is provided that includes a safety razor assembly (20) adjoined to a hair trimmer assembly (10). Both assemblies include a housing (22, 12). The housings may be separable or may be integrally formed. The trimmer assembly includes a motor (40) operably connected to a moving toothed blade (60). A second toothed blade (50) is removably mounted to the housing of the trimmer. One end of the leaf spring (90) is disposed in a suitably sized recess (18) of the trimmer housing and the opposed second end bears against a driver (80) of the moving blade to maintain sliding contact between the toothed portions of the two blades during operation. When a user removes the second toothed blade, the moving blade may be separately removed while the leaf spring is retained in its recess. Both housings have a width less than 25mm and the grooming tool is ergonomically familiar to a typical safety razor user.

lubricant compositions

Compounds and compositions for cognition-enhancement,methods of making,and methods of treating

A process for the conversion of aliphatic cyclic amines to aliphatic diamines

The instant invention is a process for the conversion of aliphatic cyclic amines to aliphatic diamines. The process for conversion of aliphatic cyclic amines to aliphatic diamines comprises the steps of: (1) selecting one or more cyclic amines; (2) contacting said one or more cyclic amines with ammonia and hydrogen, optionally water, and optionally one or more solvents in the presence of one or more heterogeneous metal based catalyst systems at a temperature in the range of from 120° C to about 250° C and a pressure in the range of from 700 to 3500 psig for a period in the range of at least one hour or more in one or more reactor systems; (3) forming a product mixture comprising one or more aliphatic diamine, optionally a portion of said one or more cyclic amines, optionally a portion of said ammonia, optionally a portion of said hydrogen, optionally water, and optionally a portion of said one or more solvents; (4) removing said product mixture from the reactor system; (5) removing at least a portion of said portion of ammonia, said portion of hydrogen, or mixture thereof from said product mixture via distillation; (6) removing at least a portion of said portion of water via distillation; (7) removing at least a portion of said portion of one or more optional solvents via distillation; (8) removing at least a portion of said portion of one or more cyclic amines; (9) thereby separating said one or more aliphatic diamines from said product mixture; and (10) thereby converting said one or more cyclic amines to one or more aliphatic diamines.

Method of lubricating a tractor hydraulic

The present invention relates to a method of lubricating a tractor with a lubricating composition containing: an oil of lubricating viscosity and a sulphur-free phosphorus-containing salt of either (i) a hydroxy-substituted di-ester of phosphoric acid, or (ii) a phosphorylated hydroxy-substituted di- or tri-ester of phosphoric acid.

Compounds and compositions for cognition-enhancement, methods of making, and methods of treating

Disclosed are muscarinic agonist compounds including oxadiazole derivatives, compositions and preparations thereof. Also disclosed are methods of synthesizing such oxadiazole compounds. Further disclosed are methods for treating a subject with said muscarinic agonists or a pharmaceutically suitable form thereof to enhance cognitive function.

Molding system

A molding system includes apparatus for moving a flask from one portion of a mold car conveyor and for transferring it across the mold car conveyor loop and for depositing the mold at another portion of the mold car conveyor. The apparatus comprises a first structure for picking up the flask from the one portion of the mold car conveyor, a flask and mold feeder movable transverse of the mold car conveyor, and a second structure for picking up a mold from the flask and mold feeder at a mold removal station, and for moving the mold to the other portion of the mold car conveyor. A single fluid cylinder is provided for effecting the movement of the flask and mold feeder, as well as the first and second structures. A linkage means interconnects the single fluid motor with the first and second structures and the flask and mold feeder to effect these various movements. In addition, the flask and mold feeder comprises a frame and roll-over mechanism is supported in the frame for effecting rolling over of the mold during movement of the flask and mold feeder. This roll-over movement is effected by a linkage which operates in response to reciprocating movement of the frame to effect the roll-over action. Further, the system includes a punch-out mechanism where the sand cake is maintained in a substantially horizontal plane and the cope and drag flasks are moved vertically to strip the sand cake from the flasks. After that vertical movement a suitable pusher member and brush move across the mold car on which the flasks have been supported to move the sand cake therefrom.