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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 733. Отображено 200.
11-05-2012 дата публикации

Composition, useful for treating or preventing gastrointestinal disorders or maintenance of the gastrointestinal health in a subject, comprises polyethylene glycol, mannitol, magnesium stearate, and a flavoring agent

Номер: FR0002967069A3
Принадлежит:

La présente invention concerne des formulations solides, en particulier des formulations solides pouvant être mâchées ou sucées, contenant du polyéthylène glycol et du mannitol. Lesdites formulations solides sont, par exemple, sous la forme de comprimés. L'invention a également pour objet un procédé de fabrication desdites formulations solides pour une utilisation dans le ramollissement des selles, l'augmentation du poids des selles, l'augmentation de la fréquence des selles ou le traitement de la constipation, d'un fécalome, d'une rétention fécale ou d'un autre trouble gastro-intestinal chez un sujet.

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07-12-2007 дата публикации

Torque intensifier for tightening and loosening threaded contractors, has housing with reaction element that receives turning force in direction opposite to that of driving element at lower speed but higher torque in preset mode

Номер: FR0002901725A1
Автор: JUNKERS, KOPPENHOEFER, VOICU, SMITH, KIM
Принадлежит: UNEX CORPORATION

Un outil amplificateur de couple pour connecteurs comporte des moyens amplificateurs de couple (6) avec une partie de boîtier (7) comprenant des moyens d'entrée, des premier et second moyens de sortie (12, 15), un entraînement (3) relié aux moyens d'entrée pour transmettre un couple de l'entraînement (3) à un connecteur avec les moyens amplificateurs (6). Dans un mode de fonctionnement, la partie de boîtier (7) et les moyens de sortie (12, 15) tournent dans la même direction, à la même vitesse, avec le même couple que les moyens d'entrée. Dans un autre mode, la partie de boîtier (7) et un des moyens de sortie (12, 15) reçoivent une force de rotation dans une direction, l'autre (12, 15) reçoit une force de rotation égale dans la direction opposée à une vitesse plus lente et avec un couple plus important.

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12-05-2006 дата публикации

MARK METROLOGY OF COVERING AND PROCESS OF MEASUREMENT Of ERROR DERECOUVREMENT IN a DEVICE HAS SEMICONDUCTOR

Номер: FR0002877767A1
Автор: SMITH, KU, PANG

Dans un procédé de métrologie de recouvrement utilisé dans la fabrication de dispositifs à semiconducteur, une marque de recouvrement (20, 30) facilite l'alignement et/ou la mesure d'erreur d'alignement de deux couches sur une structure de tranche de semiconducteur, ou de deux expositions différentes sur la même couche. Une cible (20, 30) est suffisamment petite pour être placée à l'intérieur de la zone active d'un dispositif à semiconducteur et est combinée avec des procédés de mesure appropriés permettant d'obtenir une meilleure exactitude de mesure.

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08-12-2017 дата публикации

NAVIGATION METHOD AND METHOD AND APPARATUS FOR REPAIRING A BICYCLE

Номер: FR0003052139A1
Принадлежит: REGNIER, SAVOURE, SMITH

Procédé de guidage d'un cycliste pilotant un vélo équipé d'un guidon de vélo, comprenant les étapes consistant à : - illuminer distinctement de chaque côté d'une zone de fixation centrale (30) du guidon de vélo sur une potence de vélo une zone lumineuse proximale (10a, 20a) située du côté de la zone de fixation centrale (30) ou une zone lumineuse distale (10b, 20b), en fonction de la route à suivre.

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05-09-2008 дата публикации

CEMENTING PRODUCTS HAS SURFACE GELIFIEE

Номер: FR0002892717B1
Автор: EL HAFIANE, SMITH, BONNET

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25-07-1997 дата публикации

MULTICHANNEL AND PROCEEDED NUMERICAL TRANSMITTER-RECEIVER

Номер: FR0002729026B1
Принадлежит: MOTOROLA MOBILITY, INC.

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06-12-1996 дата публикации

Cylinder head for an internal combustion engine.

Номер: FR0002711732B1
Принадлежит: AUTOSALES INCORPORATED

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08-12-2017 дата публикации

POLYMER COMPOSITION, ITS PROCESS OF PREPARATION AND ITS USE

Номер: FR0003052168A1
Принадлежит: ARKEMA FRANCE

La présente invention concerne une composition polymère comprenant un modifiant choc, un agent de mise en œuvre polymère et une charge minérale et son procédé de préparation et son utilisation. En particulier, la présente invention concerne une composition polymère comprenant un modifiant choc, un agent de mise en œuvre polymère et une charge minérale et son utilisation pour des polymères thermoplastiques. Plus particulièrement la présente invention concerne le procédé de préparation d'une composition polymère comprenant un modifiant choc, un agent de mise en œuvre polymère et une- charge minérale et son utilisation pour la transformation et/ou le traitement de polymère thermoplastiques.

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28-10-2016 дата публикации

GENERATION AND APPLICATION SHARING PERSONALIZED COMMUNICATION

Номер: FR0003025625B1
Принадлежит: E-NRJ

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30-12-2011 дата публикации

SYSTEM INCLUDING/UNDERSTANDING a FEED WATER HEATER TO EXTRACT FROM the HEAT Of a STEAM TURBINE HAS LOW PRESSURE

Номер: FR0002961851A1
Принадлежит: GENERAL ELECTRIC COMPANY

Système (2) comprenant une turbine à vapeur à basse pression (200) ; un condenseur à refroidissement par air (CRA) (400) en communication fluidique avec la turbine à vapeur à basse pression (BP) (200), le CRA (400) étant destiné à recevoir une partie de la vapeur issue d'un point d'éjection de la turbine à vapeur BP (200) ; un réchauffeur (700) d'eau d'alimentation en communication fluidique avec la turbine à vapeur à basse pression (200) par un conduit (40), le réchauffeur (700) d'eau d'alimentation étant destiné à recevoir une partie de la vapeur d'alimentation issue de la turbine à vapeur BP (200) ; et une pompe (500) à condensat en communication fluidique avec le CRA (400) et le réchauffeur (700) d'eau d'alimentation, la pompe (500) à condensat étant destinée à recevoir, du CRA (400), du fluide sous forme de condensat et, du réchauffeur (700) d'eau d'alimentation, du fluide de purge.

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19-09-2014 дата публикации

SYSTEM AND METHOD FOR IDENTIFYING AND ANALYZING ENTITIES WITH MAINTENANCE DATA

Номер: FR0003003369A1
Принадлежит: GENERAL ELECTRIC COMPANY

Il est proposé un procédé (38) pour identifier et analyser des entités de données parmi des données (d'entretien, remise en état et révision (MRO)). Le procédé comporte l'obtention (42) de données de MRO contenant des informations textuelles non structurées. Le procédé comporte aussi l'exécution (70) d'une reconnaissance d'entités nommées sur les données de MRO afin d'extraire des entités des informations textuelles non structurées et de marquer les entités avec un identifiant. Le procédé comporte en outre l'analyse heuristique (74) des entités marquées afin d'estimer une efficacité d'une réparation pour un problème spécifique ou d'estimer une fiabilité d'un organe.

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21-02-2014 дата публикации

METHOD AND SYSTEM FOR SCATTEROMETRY

Номер: FR0002880472B1

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30-07-2004 дата публикации

PROCESS OF CHARACTERIZATION OF the STAMP Of an AURAL SIGNAL ACCORDING TO At least UNDESCRIPTEUR

Номер: FR0002830118B1
Принадлежит: FRANCE TELECOM

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30-06-2017 дата публикации

PISTON UNIT OF A HYDROSTATIC RADIAL PISTON ENGINE

Номер: FR0003004226B1
Принадлежит: ROBERT BOSCH GMBH

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08-06-2012 дата публикации

CONTROL RIGIDE-DEROULEE WITH POLYMERIC SHEATH AND METHOD OF MANUFACTURE OF CONTROL RIGIDE-DEROULEE

Номер: FR0002968380A1
Принадлежит: IFP ENERGIES NOUVELLES, TECHNIP FRANCE

La conduite rigide-déroulée pour l'industrie pétrolière comporte un tube métallique 10 composé d'au moins deux tronçons de tube assemblés bout à bout par une soudure 13. Une couche de matériau isolant 11 recouvre les tronçons de tube en laissant les extrémités des tronçons libres. Un manchon annulaire en matériau de remplissage 14 recouvre le tube métallique dépourvu de couche de matériau isolant. Une gaine en matériau polymère 12 recouvre au moins une portion dudit manchon annulaire en matériau de remplissage 14 pour renforcer le tube acier 10 afin d'augmenter notablement la raideur en flexion de la conduite rigide lorsqu'elle subit des déformations dans le domaine plastique du tube acier 10.

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05-03-2010 дата публикации

CASTER Of LIGHTENING FOR GOODS

Номер: FR0002935352A1
Принадлежит: GOODRICH CORPORATION

Une roulette (10) utilisable dans des aéronefs le long d'un pont à marchandises comprend un logement (20) comportant au moins une paroi (24), un ensemble de pivot (30), un ensemble de frein (70) et au moins un ressort (50). L'ensemble de pivot (30) peut comporter au moins une paroi, des première et seconde extrémités, et une base, la première extrémité pouvant être élevée au-dessus de la seconde extrémité. La paroi peut être reliée à la paroi (24) du logement (20). L'ensemble de frein (70) peut se trouver sur la première extrémité de l'ensemble de pivot (30). Au moins un ressort (50) peut se trouver sur la seconde extrémité de l'ensemble de pivot (30). Un couvercle (54) sur ou au-dessus de l'au moins un ressort (50) peut être fixé à la paroi (24).

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29-10-1999 дата публикации

PROCESS ALLOWING TO IDENTIFY COMBINE ACTIVE IN a SYSTEM OF CORDLESS PHONE

Номер: FR0002750284B1
Автор: YOUNG, SMITH, SILVESTRI
Принадлежит: GOOGLE TECHNOLOGY HOLDINGS LLC

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02-05-2003 дата публикации

DEVICE Of Respiratory assistance

Номер: FR0002798858B1
Автор: SMITH, MCAULEY
Принадлежит: FISHER & PAYKEL LIMITED

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18-03-2005 дата публикации

Single contact/multi contact staged electric connector, has fixed connector with coaxial conducting surfaces receiving respective coaxial conducting surfaces of male plug, where surfaces have single contact

Номер: FR0002859828A1
Автор: DORANGE, SMITH
Принадлежит: CARRIER KHEOPS BAC

Le connecteur électrique cylindrique selon l'invention, constitué d'une partie de connecteur formant fiche (1) et d'une partie de connecteur complémentaire formant embase (15), laquelle reçoit en accouplement de connexion électrique ladite partie formant fiche (1), est caractérisé en ce que la partie de contact de la fiche est constituée d'au moins deux surfaces conductrices coaxiales (9a, 9b) et la partie de contact de l'embase comprend au moins deux autres surfaces conductrices (17a, 17b) complémentaires desdites surfaces conductrices de la fiche et les recevant en contact de légère pression lors de l'enfichage d'accouplement de la fiche dans l'embase, lesdites surfaces de contact de la fiche et de l'embase étant adaptées en surface de contact d'accouplement à la quantité de courant ou au nombre de courants à transmettre par le connecteur.

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04-08-2017 дата публикации

COMPOSITION FOR DYEING THE WHITE HAIRS OF THE BEARD AND HAIR WHITE SHORT AND DEVICE FOR APPLYING THE

Номер: FR0003047174A1
Автор: SMITH CEDRIC DESIRE
Принадлежит: SMITH

L'invention concerne une composition pour colorer les poils blancs de la barbe et des cheveux blancs de préférence courts. Elle concerne aussi un dispositif comprenant la dite composition et permettant de l'appliquer. Ce dispositif est sous la forme d'un feutre pour colorer soit même sans risque et rapidement les poils blancs disgracieux de la barbe et les cheveux blancs courts et clairsemés des hommes. C'est une réelle nouveauté pour les hommes et une opportunité pour les femmes. Il est constitué comme un stylo-feutre marqueur dont le corps renferme un réservoir poreux (1) imprégné d'une cartouche de coloration (2) et relier à une pointe en fibres synthétique (3).

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27-03-2015 дата публикации

METHOD FOR DISPLAYING PARAMETER

Номер: FR0003011115A1
Принадлежит: GE AVIATION SYSTEMS LIMITED

Procédé pour afficher sur un écran un paramètre modélisable par un algorithme à multiples variables afin d'assurer une compréhension d'une incidence des variables sur le paramètre, le procédé comportant l'affichage (102), sur une première partie de l'écran, d'une représentation graphique du paramètre pendant un premier laps de temps et, en même temps que l'affichage de la représentation graphique du paramètre, l'affichage (104), sur une deuxième partie de l'écran différente de la première partie, d'une représentation graphique correspondant au paramètre.

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07-08-1998 дата публикации

MULTICHANNEL HAVING AN ANTENNA IN NETWORK ADAPTIVE AND PROCEEDED TRANSMITTER-RECEIVER

Номер: FR0002737621B1
Автор: SMITH, HARRISON
Принадлежит: MOTOROLA INC

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13-11-2009 дата публикации

FORM BLADE FOR WING OF TURBINE

Номер: FR0002930965A1
Принадлежит: GENERAL ELECTRIC COMPANY

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16-11-2012 дата публикации

FORMULATIONS

Номер: FR0002967069B3
Принадлежит: NORGINE BV

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10-02-1978 дата публикации

METHOD OF PREPARING N-PHOSPHONOMETHYLGLYCINE

Номер: BG0000024411A3
Принадлежит:

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27-12-2013 дата публикации

METHOD OF ENCODING INFORMATION INTO BURSTS

Номер: FR0002977100B1
Принадлежит: CENTRE NATIONAL D'ETUDES SPATIALES

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18-03-2005 дата публикации

APPARATUS AND METHODS FOR REDUCING THE EFFECTS OF CURRENT OF DRILLING

Номер: FR0002859754A1
Принадлежит: SERVICES PETROLIERS SCHLUMBERGER

Un outil de diagraphie de puits (10) comprend un mandrin conducteur (51) ; un réseau d'antennes disposé autour du mandrin conducteur (51) , dans lequel le réseau d'antennes comprend une pluralité d'antennes disposées sur des supports isolants et au moins une entretoise de contact (53), l'entretoise de contact (53) ayant au moins une voie conductrice (55) ayant un ensemble de contact (52) disposé sur celle-ci ; et une gaine (11) disposée sur le réseau d'antennes, dans lequel la gaine (11) comprend au moins une électrode (12), l'électrode (12) et l'ensemble de contact (52) conçus pour fournir une voie radialement conductrice depuis une partie externe de l'outil de diagraphie de puits (10) vers le mandrin conducteur (51).

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19-05-2006 дата публикации

TANK OVERLAPPING FOR CROSS-COUNTRY VEHICLE

Номер: FR0002828872B1
Автор: SMITH, TORR
Принадлежит: C-DAX LIMITED

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19-10-2018 дата публикации

AIRCRAFT BROUGHT INTO WORK IN A SYSTEM FOR GENERATING ELECTRICAL ENERGY

Номер: FR0003043386B1
Принадлежит: SMITH

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01-04-2011 дата публикации

BODY OF TIGHT MEASUREMENT OF PRESSURE

Номер: FR0002950691A1

L'organe (12) de mesure de pression comprend : - une surface (106) de mesure de pression liée fonctionnellement à un corps d'épreuve (96), - un boîtier étanche (100) de mesure de pression dans lequel est agencé le corps d'épreuve (96). La surface (106) de mesure de pression est portée par une paroi déformable (104) du boîtier étanche (100) de mesure de pression s'étendant à distance du corps d'épreuve, le boîtier étanche (100) de mesure de pression délimitant un espace interne (E) au boîtier étanche (100), et - des moyens de transmission (110) de la pression entre la surface (106) de mesure de pression et le corps d'épreuve (96) comprenant un matériau (136) sensiblement incompressible occupant la totalité de l'espace interne (E).

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16-03-2007 дата публикации

“CONTROL DEVICE OF THE FUEL FLOW FOR AN APPARATUS OF REHEATING OF ENGINE HAS GAS TURBINE”

Номер: FR0002890691A1
Автор: SMITH
Принадлежит: LUCAS INDUSTRIES PUBLIC LIMITED COMPANY

Système de commande du débit de carburant vers chacun d'une série de brûleurs de rechauffage d'un moteur (10) de turbine à gaz, caractérisé en ce qu'il comprend une série de dispositifs de mesure (15) pour la régulation du débit du carburant aux brûleurs correspondants, et une série avec lesdits dispositifs respectifs, l'une des vannes à tiroirs étant pourvue de moyens de régulation du débit en réponse à une différence de pression de mesure de part et d'autre du dispositif de mesure avec laquel elle est en série, pour maintenir ladite différente pression sensiblement constante, les vannes à tiroirs restantes étant directement sensibles à la différence de pression de part et d'autre dudit dispositif de mesure, pour maintenir la différence de pression de part et d'autrre des autres dispositifs sensiblement égale à celle qui règne de part et d'autre dudit dispositif.

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11-03-2016 дата публикации

GENERATION AND APPLICATION SHARING PERSONALIZED COMMUNICATION

Номер: FR0003025625A1
Принадлежит: TRIBER

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10-10-2014 дата публикации

PISTON UNIT OF A RADIAL PISTON HYDROSTATIC MACHINE

Номер: FR0003004226A1
Принадлежит: ROBERT BOSCH GMBH

Unité de piston (12) de la machine hydraulique comportant un piston (14) et au moins un organe de roulement (18) monté à rotation dans un logement (16) du piston (14), dont la surface (30) est polie à l'état monté.

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05-05-1993 дата публикации

FUEL OIL COMPOSITIONS

Номер: CN0001071687A
Принадлежит:

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06-03-2015 дата публикации

TORQUE AMPLIFIER POWERED

Номер: FR0002901725B1
Принадлежит: UNEX CORPORATION

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02-10-1998 дата публикации

APPARATUS OF COMMUTATION OF DATA, FOR EXAMPLE IN NETWORKS HAS ASYNCHRONOUS MEANS OF TRANSPORT

Номер: FR0002736779B1
Автор: SMITH
Принадлежит: FUJITSU MICROELECTRONICS LIMITED

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11-08-2006 дата публикации

IMPROVEMENT CONCERNING OF THE LINES OF OPTICAL DELAY

Номер: FR0002840745B1
Автор: PESCOD, SMITH
Принадлежит: BAE SYSTEMS PLC

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09-09-2005 дата публикации

SPRAY CONTAINING OF THE SIMILAR GOUTELETTES HAS PEARLS

Номер: FR0002799993B1
Принадлежит: BATH & BODY WORKS INC

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18-06-2004 дата публикации

Micromachined ultrasonic transducer device useful in ultrasound imaging systems, comprises transducer array on a substrate, and body of acoustically attenuative material that supports the substrate and flexible electrical connections

Номер: FR0002848478A1
Принадлежит: GENERAL ELECTRIC COMPANY

Un dispositif transducteur à ultrasons comprend: un réseau de transducteurs à ultrasons (2) micro-usiné sur un substrat; des connexions électriques souples (16, 18) connectées au réseau de transducteurs; et un corps (14) de matière d'atténuation acoustique qui supporte le substrat et les connexions électriques souples. La matière absorbante acoustique peut contenir des caractéristiques supplémentaires, telles que des pattes ou des encoches, destinées à être utilisées pour positionner le transducteur sur des pièces fixes au cours de la fabrication ou pour positionner le transducteur à l'intérieur d'un boîtier au cours de l'assemblage final. Des pattes ou autres caractéristiques qui sont utilisées seulement pendant la fabrication peuvent être ensuite retirées du dispositif. Le dispositif MUT lui-même peut aussi être aminci pour avoir une souplesse désirée. L'impédance acoustique de la matière absorbante est de préférence adaptée à celle de la plaquette de silicium afin d'éviter, à leur interface ...

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11-08-2006 дата публикации

VERY SENSITIVE CAPACITIVE TRANSDUCER (MICROMACHINING HAS) MICRO-USINE HAS ULTRASOUNDS

Номер: FR0002881913A1
Автор: TIAN, LEE, SMITH, LI, SUN
Принадлежит: GENERAL ELECTRIC COMPANY

Transducteur capacitif à micro-usinage à ultrasons (cMUT) comprenant une électrode inférieure (12). En outre, le cMUT comprend un diaphragme (16) disposé au voisinage immédiat de l'électrode inférieure (12) de façon qu'un intervalle ayant une première largeur d'intervalle soit formé entre le diaphragme (16) et l'électrode inférieure (12). Selon une autre possibilité, le cMUT comporte au moins un élément formé dans l'intervalle, alors que l'élément au moins unique est conçu pour ménager une deuxième largeur d'intervalle entre le diaphragme (16) et l'électrode inférieure (12).

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02-07-2004 дата публикации

LIFTING CONVERTER OF FREQUENCE/MODULATEUR

Номер: FR0002738429B1
Принадлежит: MOTOROLA MOBILITY, INC.

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20-06-2008 дата публикации

IRONING BOARD SUCTION

Номер: FR0002897074B1
Автор: SMITH, DELOUYE
Принадлежит: SMITH, DELOUYE

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06-07-2018 дата публикации

CONTROL EVACUATION DROPS FOR MIST MAGNETIC SUCTION CUP

Номер: FR0003052693B1
Принадлежит: PEUGEOT CITROEN AUTOMOBILES SA

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22-12-2017 дата публикации

CONTROL EVACUATION DROPS FOR MIST MAGNETIC SUCTION CUP

Номер: FR0003052693A1
Автор: SMITH BARTHELEMY
Принадлежит: PEUGEOT CITROEN AUTOMOBILES SA

L'invention a trait à un outillage de presse d'emboutissage, comprenant une partie inférieure (2) supportant un poinçon (6) formant une surface de réception (6) d'un embouti (8), ladite surface ayant au moins un bord apte à coopérer avec une lame de découpage en vue de découper l'embouti (8) et produire au moins une chute (10, 12) ; et un bâti (4) supportant le poinçon (6) et comprenant au moins un passage d'évacuation (14, 16) de la ou d'au moins une des chutes (10, 12). La partie inférieure (2) comprend, en outre, au moins une ventouse magnétique activable (22) située dans le ou au moins un des passages d'évacuation (14, 16), au droit de la ou d'une des chutes (10, 12) avant découpage, de manière à pouvoir immobiliser ladite ou lesdites chutes après ledit découpage. L'invention a trait à un procédé de mise à forme correspondant.

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06-04-2018 дата публикации

GEOSTATISTICAL ANALYSIS MICROSEISMIC DATA WITHIN THE FRAMEWORK OF GEOMECHANICAL FRACTURE

Номер: FR0003057092A1
Принадлежит:

Un procédé peut comprendre : la modélisation d'un réseau de fractures complexes dans la formation souterraine avec un modèle mathématique sur la base d'une carte de réseau de fractures naturelles et des données mesurées de la formation souterraine collectées en association avec un traitement de fracturation de la formation souterraine afin de produire une carte de réseau de fractures complexes ; l'importation des données microsismiques collectées en association avec le traitement de fracturation de la formation souterraine dans le modèle mathématique ; l'identification des directions de continuité au sein des données microsismiques par le biais d'une analyse géostatistique qui fait partie du modèle mathématique ; et la corrélation des directions de continuité au sein des données microsismiques avec le réseau de fractures complexes à l'aide du modèle mathématique afin de produire une carte de réseau de fractures complexes à pondération microsismique (MSW).

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28-12-2012 дата публикации

PROCESS Of ENCODING OF DATA Of INFORMATION IN BURSTS

Номер: FR0002977100A1
Принадлежит: CENTRE NATIONAL D'ETUDES SPATIALES

Un procédé d'encodage de données d'information en une séquence de bursts (..., Bi-2, Bi-1, Bi, Bi+1, ...), dont chaque burst comprend un bloc de symboles d'information et un bloc de symboles de redondance. Le bloc de symboles de redondance (Ri) du burst actuel (Bi) de la séquence est généré par le calcul d'une somme d'une série de valeurs de codage relative à une série de bursts (Bi-2, Bi-1), chaque valeur de codage de la série de valeurs de codage étant obtenue par une fonction de codage respective, appliquée au bloc de symboles d'information du burst correspondant de la série de bursts.

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01-06-2012 дата публикации

STACKABLE NETWORK OF SENSORS

Номер: FR0002968124A1
Принадлежит: GENERAL ELECTRIC COMPANY

Un réseau de détecteurs empilable est réalisé par la formation d'un module de détection comprenant la réalisation d'un réseau (14) de capteurs ayant une première face (16) et une seconde face (18), le réseau (14) de capteurs comportant une première pluralité de plages de contact (20) disposées sur la seconde face (18) du réseau (14) de capteurs, la disposition du réseau (14) de capteurs sur une couche d'interconnexion (22), la couche d'interconnexion (22) comportant une couche de redistribution (24) ayant une première face et une seconde face, la couche de redistribution (24) comportant une deuxième pluralité de plages de contact (28) disposées sur la première face, un circuit intégré (26) ayant une pluralité de trous traversants d'interconnexion (30) ménagés à travers celui-ci, une première face du circuit intégré (26) coopérant avec la seconde face de la couche de redistribution (24), le réseau (14) de capteurs étant disposé sur la couche d'interconnexion (22) de façon que la première ...

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07-07-2006 дата публикации

INSULATION OF CELLS OF SENSOR COURT-CIRCUITEES FOR an OPERATION AHAUTE RELIABILITY Of a GROUPING OF SENSORS

Номер: FR0002880341A1
Автор: LEE, MILLS, CLAYDON, RIGBY, TIAN, LI, SUN, SMITH, CHU, WONG, KWON
Принадлежит: GENERAL ELECTRIC COMPANY

Il est proposé un dispositif comprenant un groupement de capteurs (12) et une multiplicité de lignes de bus, chaque capteur étant électriquement connecté à une ligne de bus respective et comprenant une multiplicité respective de groupes de cellules de capteur micro-usiné, les groupes de cellules de capteur d'un capteur particulier étant électriquement reliés l'un à l'autre par la ligne de bus à laquelle est connecté ce capteur, chaque groupe de cellules de capteur comprenant une multiplicité respective de cellules de capteur micro-usiné (12) qui sont électriquement connectées l'une à l'autre et ne peuvent pas être déconnectées l'une de l'autre par commutation, le dispositif comprenant en outre des moyens pour isoler n'importe lequel des groupes de cellules de capteur d'avec sa ligne de bus associée et en réponse au fait que l'une quelconque des cellules de capteur micro-usiné de ce groupe de cellules de capteur est court-circuitée à la masse. Dans une mise en oeuvre, les moyens d'isolement ...

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16-03-2012 дата публикации

PRODUCTS MANUFACTURES CONTAINING OF POLYMERS AND THEIR MANUFACTORING PROCESSES

Номер: FR0002964548A1
Принадлежит:

On fournit des articles manufacturés contenant un polymère qui fournissent une ou plusieurs propriétés supérieures, telles que des propriétés d'adsorption de salissures, des propriétés de nettoyage de miroir, et/ou des propriétés d'absorption, par comparaison avec des articles manufacturés contenant un polymère connus.

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23-06-2006 дата публикации

DIELECTRIC AGREEMENT OF PLANE LOW COSTS OF FILTERS E

Номер: FR0002836286B1
Автор: SMITH, CUNNINGHAM

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16-03-2018 дата публикации

DISPOSITIF A PISTONS RADIAUX HYDRAULIQUES

Номер: FR0003055925A1
Принадлежит:

Un dispositif à pistons radiaux hydrauliques comprend un boîtier, un pivot ayant un arbre de pivot, un rotor monté sur l'arbre de pivot et définissant une pluralité de cylindres et une pluralité de pistons pouvant être déplacés dans les cylindres. Le dispositif à pistons radiaux comprend en outre un anneau de piston qui fournit une interface pour les pistons. Le dispositif à pistons radiaux comprend diverses configurations pour améliorer la performance et l'efficacité du dispositif.

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19-08-2005 дата публикации

STRUCTURE OF FRAME FOR A MACHINE OF PUBLIC WORKS

Номер: FR0002774350B1
Автор: SMITH, BOYER
Принадлежит: CATERPILLAR INC

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30-10-1998 дата публикации

ALLOY Of ALUMINIUM-SILICON, AND PROCEEDED OF PROTECTION AGAINST CORROSION

Номер: FR0002735149B1
Автор: SMITH
Принадлежит: MCWANE INC

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28-09-2012 дата публикации

POWER STATION HAS CYCLE COMBINES

Номер: FR0002973073A1
Принадлежит: GENERAL ELECTRIC COMPANY

Centrale à cycle combiné (10) dans laquelle un moteur à turbine à gaz (12) génère de l'énergie, un générateur de vapeur à récupération de chaleur (GVRC) (32) produit de la vapeur à partir de fluides à haute énergie produits par la génération d'énergie dans le moteur à turbine à gaz (12), et un moteur à turbine à vapeur (18) génère de l'énergie supplémentaire à partir de la vapeur produite dans le GVRC (32). La centrale à cycle combiné (10) comprend un élément chauffant disposé sur le plan de l'écoulement entre le moteur à turbine à vapeur (18) et le GVRC (32) pour chauffer le fluide délivré par le moteur à turbine à vapeur (18) et destiné à être envoyé au GVRC (32); et un système de régulation (70, 80, 90) pour réguler une quantité de fluide délivrée par le moteur à turbine à vapeur (18), qui est chauffée par l'élément chauffant, sur la base de différences entre les températures du GVRC et les températures ambiantes.

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24-10-2014 дата публикации

METHOD FOR TRACKING OBJECTS BY HYPERSPECTRAL IMAGING

Номер: FR0003004835A1
Принадлежит: GE AVIATION SYSTEMS LLC

Procédé de suivi, par imagerie hyperspectrale, du mouvement d'au moins un objet faisant partie d'un groupe d'objets mobiles, comportant, entre autres, l'obtention (110) d'une série de trames d'image hyperspectrales ; la comparaison (114) de chaque trame de la série avec un modèle (115) pour déterminer (118) des changements sur l'image entre des trames ; l'identification (120), sur chaque trame, d'un groupe de pixels associés aux changements ; l'identification (122) de changements en tant que mouvement des objets mobiles ; la corrélation (124), trame à trame, des groupes de pixels pour déterminer dans l'espace au moins un paramètre du mouvement des objets ; et la corrélation (128) des groupes de pixels à un profil de réflectance spectrale (125) associé à l'objet/aux objets, la trajectoire de l'objet/des objets pouvant être distinguée des trajectoires d'autres objets mobiles.

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04-08-2017 дата публикации

COMPOUNDED RUBBER HAVING IMPROVED THERMAL TRANSFER

Номер: FR0003047246A1
Принадлежит:

Un élastomère composite présentant d'excellentes propriétés mécaniques et de transfert de chaleur est décrit. L'élastomère peut renfermer deux noirs de carbone différents ou plus, et l'un des noirs de carbone est un noir de carbone partiellement cristallisé.

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02-06-2006 дата публикации

Overlay mark designing method, e.g. for semiconductor device, involves illuminating overlay mark with probe beam, and measuring diffraction resulting from interaction of probe beam and overlay mark

Номер: FR0002878649A1
Автор: SMITH, KO, KU

L'invention concerne un procédé de mesures par diffusométrie utilisant une cible ayant deux réseaux (20, 22) du même pas, dans des couches supérieure et inférieure, avec une couche intermédiaire (24) située entre ces couches supérieure et inférieure et un substrat (26). Le réseau de cible est conçu afin de rendre la mesure de superposition plus sensible sur le substrat de l'échantillon en fonction de paramètres de la structure et de la matière du substrat, déterminés au préalable. Une longueur d'onde de mesures appropriées est choisie pour améliorer la sensibilité. Domaine d'application : Fabrication de semi-conducteurs et autres dispositifs à l'échelle microscopique.

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13-06-2014 дата публикации

STAGE ELECTRICAL CONNECTOR

Номер: FR0002859828B1
Принадлежит: CARRIER KHEOPS BAC

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22-02-2002 дата публикации

IMPROVEMENTS WITH the SYSTEMS MADE SAFE FOR ORDER DUDEVERROUILLAGE Of AT LEAST ONE OPENING OF MOTOR VEHICLE

Номер: FR0002800783B1
Автор: MENARD, SMITH
Принадлежит: VALEO SECURITE HABITACLE

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03-01-2003 дата публикации

TRANSMITTER Of a SYSTEM OF Wireless telecommunications

Номер: FR0002738428B1
Принадлежит: MOTOROLA MOBILITY, INC.

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11-12-2009 дата публикации

HEAT RECOVERY SYSTEM LOST GENEREE BY AN AUXILIARY SYSTEM OF TURBOSHAFT ENGINE.

Номер: FR0002932220A1
Принадлежит: GENERAL ELECTRIC COMPANY

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02-02-2018 дата публикации

SYSTEM FOR MANAGING FLIGHT PATH

Номер: FR0003054712A1
Принадлежит:

La présente invention propose des systèmes et des procédés pour la détermination d'une trajectoire de vol d'un aéronef. Selon un mode de réalisation, un procédé (500) peut comprendre l'identification d'un ou plusieurs paramètres associés à une cible mobile (504). Le procédé (500) peut comprendre la détermination d'une trajectoire de vol circulaire mobile associée à la cible mobile (506), sur la base, au moins en partie, du ou des paramètres associés à la cible mobile. Le procédé (500) peut comprendre l'identification d'un ou plusieurs états associés au moins à l'aéronef ou à la trajectoire de vol circulaire mobile (508). Le procédé (500) peut comprendre la détermination d'une trajectoire de vol de l'aéronef (510) à partir d'une position de l'aéronef jusqu'à la trajectoire de vol circulaire mobile, sur la base, au moins en partie, du/des paramètre(s) associé(s) à la cible mobile et du/des état(s) associé(s) au moins à l'aéronef ou à la trajectoire de vol circulaire mobile.

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12-05-2017 дата публикации

AIRCRAFT ŒUVRE BROUGHT IN A PRODUCING ELECTRICAL ENERGY

Номер: FR0003043386A1
Автор: SMITH GARRETT
Принадлежит: SMITH

L'aéronef (10) comporte : - un ballon (100) s'étendant entre deux extrémités latérales (101, 101') dudit ballon, lesdites deux extrémités latérales du ballon définissant un axe R dudit ballon,- des moyens de liaison (110) comportant au moins deux branches latérales (111), (111') reliées respectivement aux deux extrémités latérales dudit ballon, ledit ballon étant monté, sur lesdites deux branches latérales, mobile en rotation autour de l'axe R, lesdits moyens de liaison étant destinés à être reliés au sol, - un moteur (120), adapté à entraîner le ballon en rotation autour de l'axe R, et - des moyens de contrôle de l'orientation du ballon par rapport au vent.

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20-06-2008 дата публикации

SYSTEM AND METHOD FOR ACTIVELY COOLING A ULTRASONIC PROBE.

Номер: FR0002910169A1
Принадлежит: GENERAL ELECTRIC COMPANY

Système d'échographie (10) pour réaliser une image d'un objet. Le système d'échographie (10) comprend une sonde échographique (52) pour acquérir des données d'échographie et un sous-système de refroidissement (54) pour évacuer de manière active de la chaleur de la sonde échographique (52). Le sous-système de refroidissement (54) comprend une pompe (62) disposée à l'intérieur d'un réservoir (68) contenant un agent de refroidissement (64) agencée pour faire circuler l'agent de refroidissement (64) dans la sonde échographique (52) via un conduit (66).

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19-10-2007 дата публикации

PROCEEDED WITH SELECTIVE REHEATING Of AIR TO the ENTRY Of a COMPRESSOR ASSOCIATES HAS a GAS TURBINE AND System of production Of ELECTRICITY.

Номер: FR0002899936A1
Автор: SMITH, GULEN, GARDINER
Принадлежит: GENERAL ELECTRIC COMPANY

Système capable à la fois d'accroître la puissance délivrée par temps chaud et de maintenir la marge de fonctionnement d'un compresseur à toutes les valeurs de températures ambiantes et de charges d'une installation de turbine à gaz ainsi que le combiné. La solution proposée bénéficie du fait que les deux objectifs peuvent être atteints par manipulation de la température de l'air d'entrée du compresseur. En particulier, le système est conçu pour réchauffer l'air d'entrée comme cela peut être nécessaire pour maintenir une bonne marge de fonctionnement du compresseur à de basses températures d'air ambiant ou lors de la combustion de combustibles dilués. Selon l'autre possibilité, le système est conçu pour refroidir de l'air d'entrée par temps chaud.

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10-06-2016 дата публикации

GRILLE FOR MAINTAINING NUCLEAR FUEL ASSEMBLY

Номер: FR0003029677A1
Принадлежит: WESTINGHOUSE ELECTRIC COMPANY LLC

Grille d'assemblage combustible nucléaire dotée d'un ensemble d'ailettes de mélange en forme de torpilles montées sur chaque intersection des plaquettes (86, 88) de grille qui entoure un emplacement de maintien de crayon combustible. La tige (104) en forme de torpille porte des ailettes de mélange (102) qui s'étendent sur chacun des emplacements de maintien de crayon combustible.

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14-11-2008 дата публикации

AIRCRAFT HAS SPACE USEFUL OPTIMIZES AND METHOD FOR OPTIMIZING the USEFUL SPACE Of an AIRCRAFT

Номер: FR0002904965B1
Автор: SMITH
Принадлежит: AIRBUS

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07-07-2006 дата публикации

PROCESS AND SYSTEM OF DIFFUSOMETRIE

Номер: FR0002880472A1
Автор: SMITH, KU, WANG, KO

L'invention concerne un système et un procédé pour déterminer efficacement et avec précision des profils de réseau en utilisant une adaptation de signature caractéristique. Un diffusomètre (20) comporte une source de lumière (30) et un détecteur (32) au moyen desquels il est possible de déterminer avec précision un décalage ΔOL de superposition de réseaux. Domaine d'application : fabrication de semiconducteurs, etc.

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08-10-2010 дата публикации

APPARATUS AND METHOD FOR TRANSFERRING HEAT

Номер: FR0002944099A1
Принадлежит: RIGIDIZED METALS CORPORATION

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06-03-2009 дата публикации

VALVE Of STARTING AND ELECTRIC ORDERING OF PRESSURE COMBINEES FOR PUMPS OF GUN HAS PAINTING

Номер: FR0002920419A1
Принадлежит: WAGNER SPRAY TECH CORPORATION

Un appareil de soupape d'amorçage et de commande de pression électrique combiné (10) comprend un actionneur de soupape d'amorçage (22, 23, 76), un actionneur de commande de pression électrique (38), et un boîtier de commande (12, 12') comprenant les actionneurs, chacun couplé à un arbre unique (54) ayant un ensemble de cames pour actionner sélectivement l'appareil de commande (10) dans l'un parmi un mode d'amorçage et un mode de pulvérisation et la commande de pression électrique peut être actionnée dans une plage de réglages de pression par le mouvement de l'arbre (54) alors que l'appareil de commande (10) reste en mode de pulvérisation. Les actionneurs sont orientés de manière diamétralement opposée et décalés le long d'un axe de l'arbre unique (54) les uns par rapport aux autres, et sont en contact avec l'ensemble de cames et en contact respectivement avec un levier pour une soupape d'amorçage et un support de commutateur de pression. Une vis de serrage (180) dans le support fournit ...

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20-12-2012 дата публикации

Verfahren zur Herstellung von Transistoren mit selbstausrichtenden Steuerelektroden (Gate) und Source-/Drainzonen

Номер: DE112010003087T5
Принадлежит: CREE INC, CREE, INC.

Verfahren zum Ausbilden eines Transistorbauelements aus Gruppe III-Nitrid enthalten die Ausbildung einer Schutzschicht auf der Halbleiterschicht aus Gruppe III-Nitrid, die Ausbildung eines Kontaktlochs durch die Schutzschicht, um einen Abschnitt der Halbleiterschicht aus Gruppe III-Nitrid freizulegen, und die Ausbildung eines Maskierungs-Gate auf der Schutzschicht. Das Maskierungs-Gate enthält einen oberen Abschnitt mit einer größeren Breite als die Breite des Kontaktlochs und einen unteren Abschnitt, der sich in das Kontaktloch erstreckt. Die Verfahren enthalten ferner das Implantieren von Source-/Drain-Zonen in der Halbleiterschicht aus Gruppe III-Nitrid, wobei das Maskierungs-Gate als Implantationsmaske dient.

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02-08-2012 дата публикации

Determination of melting temperatures of dna

Номер: US20120197537A1
Автор: Ronald T. Kurnik
Принадлежит: Roche Molecular Systems Inc

Numerical determinations of the first derivatives of a melt curve data set are made. A model function, such as a Gaussian Mixture Model (GMM) function, with parameters determined using a Levenberg-Marquardt (LM) regression process is used to find an approximation to the first derivative curve. The maximum values of the numerically determined first derivative values are used as initial conditions for parameters of the model function. The determined parameters provide one or more fractional melting temperature values, which can be returned, for example, displayed or otherwise used for further processing.

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16-08-2012 дата публикации

Regenerative braking safety system and method of use

Номер: US20120206071A1
Принадлежит: Beckman Coulter Inc

A centrifuge includes a regenerative braking safety system including an electrical system reversibly coupled to a power source. A motor is coupled to the electrical system. The motor is capable of driving a rotor using power delivered through the electrical system, and is further capable of supplying the electrical system with recovered energy. The recovered energy is electrical energy converted from kinetic energy of the rotor during regenerative braking of the motor. The safety system includes a power cut-off configured to disable the effect of regenerative braking of the motor when the electrical system is decoupled from the power source.

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10-01-2013 дата публикации

Cytotoxic ribonuclease variants

Номер: US20130011904A1
Принадлежит: WISCONSIN ALUMNI RESEARCH FOUNDATION

Cytotoxic variants of human ribonuclease 1 (RNase 1) identified through analysis of the interaction between RNase 1 and the human ribonuclease inhibitor (hRI) as defined by the three dimensional (3-D) atomic structure of the RNase1 hRI complex are disclosed. Also disclosed is the 3-D structure of the hRI·RNase 1 complex and methods for designing the RNase 1 variants.

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28-03-2013 дата публикации

Ophthalmic endoilluminators with directed light

Номер: US20130079598A1
Принадлежит: Alcon Research LLC

Certain embodiments of an endoilluminator may include a cannula, an intermediate material, and an optical fiber. The cannula has a substantially cylindrical shape that defines an interior region and has a cylindrical axis. The intermediate material is disposed within the interior region. The optical fiber is disposed within the intermediate material and has a fiber optical axis and a distal end configured to emit light. The emitted light has an illumination pattern with an illumination axis that is not parallel to the cylindrical axis.

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13-02-2014 дата публикации

Method and system for improving spatial efficiency of a furnace system

Номер: US20140045133A1
Принадлежит: Foster Wheeler USA Corp

A furnace system includes at least one lower radiant section having a first firebox disposed therein and at least one upper radiant section disposed above the at least one lower radiant section. The at least one upper radiant section has a second firebox disposed therein. The furnace system further includes at least one convection section disposed above the at least one upper radiant section and an exhaust corridor defined by the first firebox, the second firebox, and the at least one convection section. Arrangement of the at least one upper radiant section above the at least one lower radiant section reduces an area required for construction of the furnace system.

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10-03-2022 дата публикации

Reagents and methods for esterification

Номер: US20220073899A1
Принадлежит: WISCONSIN ALUMNI RESEARCH FOUNDATION

Methods and reagents for esterification of biological molecules including proteins, polypeptides and peptides. Diazo compounds of formula I:where R is hydrogen, an alkyl, an alkenyl or an alkynyl, RA represents 1-5 substituents on the indicated phenyl ring and RM is an organic group. RM includes a label, a cell penetrating group, a cell targeting group, or a reactive group or latent reactive group for reaction to bond to a label, a cell penetrating group, or a cell targeting group, among other organic groups useful for esterification of biological molecules. Also provided are diazo compounds which are bifunctional and trifunctional coupling reagents as well as reagents for the synthesis of compounds of formula I.

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26-06-2014 дата публикации

Grin fiber multi-spot laser probe

Номер: US20140180264A1
Принадлежит: Alcon Research LLC

A surgical probe includes a cannula assembly, having a graded index (GRIN) fiber that is configured to receive a multi-spot light beam at a proximal end and to emit the multi-spot light beam at a distal end ; an adapter, having a distal end, configured to receive the cannula assembly, with the proximal end of the GRIN fiber, a proximal end, configured to couple to a light guide via a connector and to receive a light delivered by the light guide from a laser source to the adapter, and an interface, configured to couple the light delivered by the light guide to the proximal end of the GRIN fiber; wherein a length of the GRIN fiber is sufficiently long that the interface is outside a patient's eye during a photocoagulation procedure.

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24-07-2014 дата публикации

Product dispensing system

Номер: US20140203017A1
Принадлежит: Sage Products LLC

A product dispensing system and a method of queuing usage of products. In one form, a plurality of layers of products, each having multiple items in separate packages, is provided, each layer having a carrier with the separate packages being secured to and extending from the carrier. The layers are assembled in a stacked orientation behind a front layer with layers behind the front layer being at least partially concealed and inaccessible. Products are used one layer at a time, and when the separate packages from the front layer are removed, the packages of the next-succeeding layer are exposed for use. In another form of the invention, the packages for each layer are secured to and extend in series from the carrier for each layer, with a first package secured to the carrier for the layer, and each succeeding package being secured to the next preceding package. The carrier and packages of each layer are secured to one another with successive package connections of increasing strength with increasing distance from a package most distant from the carrier.

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12-05-2016 дата публикации

Apparatus for removing infrared (ir) light from an ophthalmic illumination system

Номер: US20160128557A1
Принадлежит: NOVARTIS AG

An ophthalmic illumination apparatus includes a light source operable to generate a light beam and a filtering mirror configured to generate an infrared (IR) filtered light beam by reflecting at least a portion of wavelengths of the light beam in the visible spectrum while filtering out at least a portion of wavelengths of the light beam in the IR spectrum. The ophthalmic illumination apparatus further includes a collimator configured to receive at least a portion of the IR filtered light beam and generate a collimated light beam and a condenser configured to couple at least a portion of the collimated light beam into an optical fiber.

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25-08-2022 дата публикации

Single fiber illuminated laser probe with high-angle illumination output

Номер: US20220268990A1
Принадлежит: Alcon Inc

The present disclosure relates to a fiber and a laser probe assembly with a probe tip that houses the fiber. In certain aspects, the fiber includes a core, an outer cladding surrounding the core, and an end face at a proximal and/or distal end of the fiber. The core is configured to transmit a laser light beam while the core and the outer cladding are both configured to transmit an illumination light. In certain aspects, a surface area of the end face corresponding to a cross-section of at least the outer cladding is treated with a roughening or polishing process to modulate an illumination light output angle of the fiber. Using a fiber that is configured to transmit a laser light beam as well as a wide-angle illumination light allows for a more compact fiber and probe tip, allowing for medical procedures that require a narrower probe.

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16-04-2020 дата публикации

Real time holography using learned error feedback

Номер: US20200117139A1
Принадлежит: Intel Corp

Techniques related to generating holographic images are discussed. Such techniques include application of a pre-trained deep neural network to a target holographic image to generate a feedback strength value for error feedback in an iterative propagation feedback model and generating a diffraction pattern image corresponding to the target holographic image by applying the iterative propagation feedback model based on the target holographic image and using the feedback strength value.

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17-05-2018 дата публикации

Medical instrument with an integrated optical fiber

Номер: US20180132963A1
Принадлежит: NOVARTIS AG

Provided herein is an illuminated microsurgical instrument system and an illuminated microsurgical instrument. In one implementation, the system includes a microsurgical instrument having a distally projecting tubular member arranged to perform a medical procedure at an interventional site. The tubular member has a distal tip and an outer surface, the outer surface having a flat surface formed therein. The instrument includes a sheath member surrounding a portion of the tubular member and extending toward the distal tip of the tubular member and an optical fiber extending along a length of the flat surface between the tubular member and the sheath member. The instrument may further include a slack chamber, collar structure, and fiber guard member to support and guide the optical fiber to the distal tip.

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22-06-2017 дата публикации

Diverging Light from Fiber Optics Illumination Delivery System

Номер: US20170176660A1
Принадлежит: NOVARTIS AG

An illumination fiber optics is provided that includes an optical fiber, configured to receive illumination light at a proximal end from a light source; and a light-scattering element, at a distal end of the optical fiber, configured to receive the illumination light from the optical fiber at a proximal end and to emit the illumination light at a distal end in a wide angle. The illumination fiber optics can be prepared by providing an optical fiber, configured to receive illumination light at a proximal end from a light source; and creating a light-scattering element at a distal end of the optical fiber, configured to receive the illumination light from the optical fiber at a proximal end and to emit the illumination light at a distal end in a wide angle.

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19-08-2021 дата публикации

Multi-spot laser probe with multiple single-core fibers

Номер: US20210255388A1
Принадлежит: Alcon Inc

The present disclosure relates to a laser probe assembly coupled to a laser system through an optical fiber cable. In one example, the laser probe assembly comprises a probe tip coupled to the probe body, the probe tip housing multiple fibers. Each of the multiple fibers comprises a proximal end that couples to the laser system and a distal end that terminates in the probe tip, a single core for transporting a laser beam provided by the laser system, and a cladding surrounding the core. The laser probe assembly also comprises a lens for projecting multiple laser beams provided by the multiple fibers on to a surgical site. Within the probe tip, parts of outer surfaces of portions of any two adjacent fibers of the multiple fibers touch. Also, the multiple fibers are at least substantially centered with respect to the lens.

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29-09-2016 дата публикации

Inhibitors of collagen prolyl 4-hydroxylase

Номер: US20160280701A1
Принадлежит: WISCONSIN ALUMNI RESEARCH FOUNDATION

Biheteroaryl dicarboxylates and esters, and salts thereof which are useful as modulators of CP4H activity and more particularly as inhibitors of CP4H. Compounds of formula: and salts thereof where: X is S, O, NH, or NR, where R is an alkyl group having 1-3 carbon atoms; R 1 and R 2 independently are —OR 7 , or —NHSO 2 R 8 , where R 7 is selected from: hydrogen, alkyl, alkenyl, alkoxyalkyl, —R′—CO—R″, —R′—CO—O—R″, —CO—R″, —R′—O—CO—R″, —R′—CO—NR″, —CO—NR″, or —R′—O—CO—NR″, and R 8 is selected from hydrogen, alkyl, aryl, arylalkyl; R 3 , R 4 and R 6 independently are hydrogen, alkyl, alkoxy, alkenyl, alkenoxy, halo alkyl, haloalkenyl, halogen, hydroxyl, hydroxyalkyl, hydroxyalkenyl, aryl, aryloxy, arylalkyl or arylalkyloxy; R 5 is hydrogen, halogen, alkyl having 1-3 carbon atoms, or alkoxy having 1-3 carbon atoms; —R′— is a divalent straight chain or branched alkylene, and —R″ is an alkyl, alkenyl, arylalkyl, or aryl group. Methods for inhibition of CP4H in vivo and in vitro.

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21-08-1984 дата публикации

Automatic sieve and chaffer adjustment in a combine harvester

Номер: US4466231A
Принадлежит: Sperry Corp

In a combine harvester, a microprocessor controls the adjustment of the cleaning sieve or sieves and/or chaffer sieve or sieves in response to information keyed into a keyboard by the combine operator. If the actual setting of a device (sieve or chaffer) is greater than the desired setting the device is first fully opened and maintained in that position for a predetermined period of time to allow foreign objects and crop material to clear itself from the device by normal combine operation. This avoids damage to the control linkage, sieve slats, and so forth. After the device is fully opened and maintained open for the predetermined interval of time it then closes beyond the desired setting by some predetermined amount after which the device is opened to the desired setting. This arrangement insures that the approach to the final adjustment is always made as the device is being opened, thereby allowing for compensation of play or backlash in the mechanical linkages which adjust the device.

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20-10-1992 дата публикации

Distance measurement and control using coded sonic signals

Номер: US5155983A
Принадлежит: Ford New Holland Inc

An agricultural harvesting machine having a cutting element movably supported thereon is provided with a height sensor including a transmitter and a receiver mounted for movement with the cutting element. The transmitter directs bursts of sound waves in the range of about 5 KHz toward the ground and echoes of the bursts are picked up by the receiver, the elapsed time between transmission and reception being an indication of the height of the cutting element above the ground. To distinguish between echoes of the bursts and environmental noise picked up by the receiver, the bursts are encoded by transmitting them in pairs, the bursts of a pair being of fixed duration and separated by a fixed interval of time. The duration of each signal and the time spacing between signals is checked and if they are not of the correct duration or are not separated by the fixed interval of time they are rejected as noise. The time between transmission and reception of a burst is measured to provide an indication of the height of the cutting element. The measured height is compared with a reference or desired height and the difference value is used to control movement of the cutting element to the desired height.

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23-09-1986 дата публикации

Automatic sieve and chaffer adjustment in a combine harvester

Номер: CA1211821A
Принадлежит: Sperry Corp

AUTOMATIC SIEVE AND CHAFFER ADJUSTMENT IN A COMBINE HARVESTER ABSTRACT In a combine harvester, a microprocessor controls the adjustment of the cleaning sieve or sieves and/or chaffer sieve or sieves in response to information keyed into a keyboard by the combine operator. If the actual setting of a device (sieve or chaffer) is greater than the desired setting the device is first fully opened and maintained in that position for a predetermined period of time to allow foreign objects and crop material to clear itself from the device by normal combine operation. This avoids damage to the control linkage, sieve slats, and so forth. After the device is fully opened and maintained open for the predetermined interval of time it then closes beyond the desired setting by some predetermined amount after which the device is opened to the desired setting. This arrangement insures that the approach to the final adjustment is always made as the device is being opened, thereby allowing for compensation of play or backlash in the mechanical linkages which adjust the device.

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03-03-1988 дата публикации

Automatic sieve and chaffer adjustment in a combine harvester

Номер: DE3375443D1
Принадлежит: New Holland Inc

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27-01-1988 дата публикации

Automatic sieve and chaffer adjustment in a combine harvester

Номер: EP0104676B1
Принадлежит: New Holland Inc

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02-07-1985 дата публикации

Automatic combine harvester adjustment system

Номер: US4527241A
Принадлежит: Sperry Corp

The adjustment of operating parameters such as the sieve opening, concave opening, chaffer opening, rotor speed and/or fan speed is/are accomplished under the control of a microprocessor operating in response to the striking of keys on a keyboard. The combine harvester operator may select a particular parameter for adjustment by striking a key corresponding to that parameter. The desired setting of the selected parameter is then keyed into the keyboard and an ADJUST key struck to activate the adjustment process. Alternatively, the operator may strike a key corresponding to the crop to be harvested, a further key corresponding to the ambient moisture level of the crop, and then the ADJUST key. In this case the microprocessor reads from a stored table the values for adjusting all parameters so as to obtain a satisfactory sample and a maximum yield for the crop being harvested. The microprocessor sends signals to actuators for adjusting the various parameters and transducers sense the various parameters and provide information to the microprocessor for determining when the parameters have been adjusted to the selected values. A visual display is provided so that the operator may monitor the parameters and also observe entries keyed in at the keyboard.

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04-04-1984 дата публикации

Automatic sieve and chaffer adjustment in a combine harvester

Номер: EP0104676A2
Принадлежит: New Holland Inc, Sperry Corp

In a combine harvester, a microprocessor (100) controls the adjustment of the cleaning sieve or sieves (132) and/or chaffer sieve or sieves (130) in response to information keyed into a keyboard (110) by the combine operator, If the actual setting of a device (130-132) (sieve or chaffer) is greater than the desired setting the device is first fully opened and maintained in that position for a predetermined period of time to allow foreign objects and crop material to clear itself from the device by normal combine operation. This avoids damage to the control linkage, sieve slats, and so forth. After the device is fully opened and maintained open for the predetermined interval of time it then closes beyond the desired setting by some predetermined amount after which the device is opened to the desired setting. This arrangement insures that the approach to the final adjustment is always made as the device is being opened, thereby allowing for compensation of play or backlash in the mechanical linkages which adjust the device.

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19-08-2003 дата публикации

Immunochromatographic assay method and apparatus

Номер: US6607922B2
Автор: Ronald T. LaBorde
Принадлежит: Quantum Design Inc

An immunochromatographic assay employing superparamagnetic particles to lable the target analytes. An opaque cover prevents misinterpretive readings in field situations and provides a protective surface on the porous membrane. Additional features include separability of the test strip from any backing or housing which is configured to support the strip, and that quantitative measurements of the target analytes are easily and accurately made by means of an electromagnetic reader device.

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13-12-2007 дата публикации

Directed-flow assay device

Номер: US20070287198A1
Принадлежит: Quantum Design Inc

A diagnostic assay device that directs an applied sample to the analytical membrane of a directed flow device. The device has a sample receiving port defined by layers of built-up material on one end of the test strip. The port contains the sample and specifically directs it to the membrane in a controlled fashion. Additional features include configuration of the housing in a general C-shape with the test strip spanning the opening of the C-shape to allow access by a reader device. A preferred method employs superparamagnetic particles to label the target analytes for detection and measurement by means of an electromagnetic reader device.

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16-06-2009 дата публикации

Directed-flow assay device

Номер: US7547557B2
Принадлежит: Quantum Design Inc

A diagnostic assay device that directs an applied sample to the analytical membrane of a directed flow device. The device has a sample receiving port defined by layers of built-up material on one end of the test strip. The port contains the sample and specifically directs it to the membrane in a controlled fashion. Additional features include configuration of the housing in a general C-shape with the test strip spanning the opening of the C-shape to allow access by a reader device. A preferred method employs superparamagnetic particles to label the target analytes for detection and measurement by means of an electromagnetic reader device.

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03-03-2015 дата публикации

Frazil ice conjugate assay device and method

Номер: US8968677B2
Принадлежит: Quantum Design International Inc

An improved apparatus and method for dispersion of a labeling conjugate in a diagnostic assay, the result being a one-step assay. By eliminating a conjugate pad as in conventional lateral diagnostic devices, and forming a frazil ice pellicle (FIP), rehydration and flow are improved resulting in better reproducibility, improved sensitivity, and reduced costs of individual assay devices. The formation of a frazil ice film formed on a super cooled surface of a sample receiving means simplifies assay assembly. Lyophilization of the FIP improves the release of a sample/analyte/label matrix into a macro channel as in a direct flow assay, while at the same time allowing reagents to mix and flow, thereby optimizing the assay performance. The reagents of the conjugate and the formation of the FIP stabilize the conjugate proteins and provide extended shelf life to the diagnostic assay device.

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29-01-2008 дата публикации

Accessible assay and method of use

Номер: US7323139B2
Принадлежит: Quantum Design Inc

An assay test strip and cassette. The test strip is positioned in a housing shaped and configured to allow a detector to access the test strip from the side, rather than from the lengthwise axis of the test strip. The housing may contain one or more test strips which may also be disposed on one or more surfaces of the housing. Preferably, the housing is generally C-shaped with the test strip spanning the space between the two arms of the C-shape. The housing is sealed to protect both the operator and instrument from possible contamination. The test strip is preferably embedded with paramagnetic particles and process chemistry specific for a particular application. Quantitative analysis may be accomplished using a magnetic reader device. In additional embodiments, detection is accomplished by visual means.

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17-02-2021 дата публикации

Superparamagnetic particle imaging and its applications in quantitative multiplex stationary phase diagnostic assays

Номер: EP3775950A1
Принадлежит: Mars Sciences Ltd

Superparamagnetic nanoparticle-based analytical method comprising providing a sample having analytes in a sample matrix, providing a point of care chip having analytical regions, each of which is a stationary phase having at least one or more sections, labeling each of the analytes with a superparamagnetic nanoparticle and immobilizing the labeled analytes in the stationary phase, providing an analytical device having a means for exciting the superparamagnetic nanoparticles in vitro and a means for sensing, receiving, and transmitting response of the excited superparamagnetic nanoparticles, placing the chip in the analytical device and exciting the superparamagnetic nanoparticles in vitro, sensing, receiving, and transmitting the response of the superparamagnetic nanoparticles, and analyzing the response and determining characteristic of the analytes, wherein the response of the superparamagnetic nanoparticles comprises harmonics. The present invention also provides the hybrid point of care chip and analyzer to be used in the analytical method.

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28-04-1998 дата публикации

Quarter-wave film for brightness enhancement of holographic thin taillamp

Номер: US5745266A
Автор: Ronald T. Smith
Принадлежит: Raytheon Co

A holographic thin rear exterior lamp for a vehicle including a light pipe (11) having first and second opposing surfaces (11a, 11b), a rear exterior lamp hologram (13, 113) attached to one of the first and second surfaces of the light pipe, a polarization rotating retarder film (16, 116) attached to one of the first and second opposing surfaces oppositely from the rear exterior lamp hologram, a light source (17, 19) for providing a substantially collimated beam, a transmission hologram (15) disposed on one of the first and second surfaces of the light pipe for coupling the substantially collimated beam into the light pipe such that a portion of the substantially collimated light propagates by total internal reflection within the light pipe, the rear exterior lamp hologram and the polarization rotating retarder film. The polarization rotating retarder film is configured to impart a substantially halfwave retardance to internally reflected light that passes twice therethrough.

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29-10-2020 дата публикации

Superparamagnetic particle imaging and its applications in quantitative multiplex stationary phase diagnostic assays

Номер: AU2019252255A1
Принадлежит: Mars Sciences Ltd

Superparamagnetic nanoparticle-based analytical method comprising providing a sample having analytes in a sample matrix, providing a point of care chip having analytical regions, each of which is a stationary phase having at least one or more sections, labeling each of the analytes with a superparamagnetic nanoparticle and immobilizing the labeled analytes in the stationary phase, providing an analytical device having a means for exciting the superparamagnetic nanoparticles in vitro and a means for sensing, receiving, and transmitting response of the excited superparamagnetic nanoparticles, placing the chip in the analytical device and exciting the superparamagnetic nanoparticles in vitro, sensing, receiving, and transmitting the response of the superparamagnetic nanoparticles, and analyzing the response and determining characteristic of the analytes, wherein the response of the superparamagnetic nanoparticles comprises harmonics. The present invention also provides the hybrid point of care chip and analyzer to be used in the analytical method.

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23-08-1994 дата публикации

Waveguide holographic telltale display

Номер: US5341230A
Автор: Ronald T. Smith
Принадлежит: Hughes Aircraft Co

A waveguide holographic telltale display for displaying images to a vehicle driver via the vehicle windshield. A light source injects light into the base of a clear inner windshield singlet. A mirror hologram between the inner and outer singlets confines a majority of the injected light to the inner singlet. An image hologram between the windshield singlets diffracts light out to the vehicle driver. A halfwave plate between the image hologram and the inner singlet reduces ghosting and allows the driver to view the images even through polarized sunglasses. IR light is blocked by a tinted outer singlet or a holographic solar coating. The display does not suffer from ambient turn from the sun, and the light source is hidden away from the vehicle dash.

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31-03-1998 дата публикации

メモリシステム、i/oサブシステムデバイスおよびメモリ装置を動作させる方法

Номер: JPH1083673A
Принадлежит: Cirrus Logic Inc

(57)【要約】 【課題】 独立した各種タスクをおこない、および/ま たは互いに異なる速度で動作するデバイス間のパフォー マンス上の格差を最小化する、改良されたI/Oサブシ ステムおよびI/Oサブシステムデバイス(特にコアロ ジック)を提供する。 【解決手段】 メモリ20は、第1のメモリセルアレイ 100と、第2のメモリセルアレイ102と、を有して いる。第1のデータポート118は、第1のアレイ10 0とのデータのやりとりを可能にし、第2のデータポー ト120は、第2のアレイ102とのデータのやりとり を可能にする。また、メモリシステム20は、ある選択 されたモードにおける、第1のアレイ100とのデータ のやりとりを第1のデータポート118を介して制御 し、第2のアレイ102とのデータのやりとりを第2の データポート120を介して制御する回路122も備え ている。ここで、第1および第2のアレイ100および 102とのデータのやりとりは、非同期的におこなわれ る。

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03-09-2019 дата публикации

Ophthalmic illumination system with controlled chromaticity

Номер: US10400967B2
Автор: Ronald T. Smith
Принадлежит: NOVARTIS AG

An ophthalmic illumination system includes a light source to emit a light beam and a filter comprising a clear region to transmit visible light in the visible spectrum and a first filtered region to transmit visible light in a first spectral range. The filter is arranged within the optical path of the beam. The system includes a plurality of chromaticity sensors to receive a portion of the light beam transmitted by the filter and output a signal indicating chromaticity of the received beam. The system also includes a processor to receive the signal indicating chromaticity, compare the indicated chromaticity to a target chromaticity stored in memory and, based on the comparison, adjust the chromaticity of the light beam transmitted by the filter by generating a signal to move the filter from a first position in which the light beam is incident upon only the clear region to a second position in which the light beam is partially incident on both the clear region and the first filtered region.

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31-08-1982 дата публикации

Body fluid collection device with disposable liner

Номер: US4346711A
Принадлежит: Sherwood Medical Industries Inc

A medical drainage collection device of the disposable liner type wherein the problems of connecting and disconnecting the liner from the canister of a device is simplified by providing a resilient locking device on a canister cover which receives a snap-in tube connector fixed to the disposable liner. Pressure applied to the locking device resiliently releases the connector from the cover. The liner can be provided with a hydrophobic filter which filters air before reaching the vacuum system to prevent system contamination, and when covered by drainage liquid closes off further gas or air flow through the filter to also provide a maximum-fill shut-off thereby preventing overfilling.

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05-01-1993 дата публикации

Seat suspension with quick height adjustment

Номер: US5176356A
Принадлежит: Milsco Manufacturing Co

A seat suspension having a stationary support that can be mounted on a vehicle. An intermediate frame is mounted on the stationary support for vertical sliding movement relative thereto by a spring suspension. A seat support frame is mounted on the intermediate frame for upward or downward movement relative thereto. A ratchet assembly interconnects the seat support frame and the intermediate frame and includes ratchet members on one of the frames and a pawl member on the other of the frames. A pawl release, including a biasing spring and a pawl actuating member, is provided to allow the support frame to be moved from the lower to any intermediate upper position and create an impulse at each position without need to activate said activating member. The activating member is operative to selectively move the pawl to a nonengagement position.

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23-07-2008 дата публикации

Analytical multi-spectral optical detection system

Номер: EP1946081A1

Analytical multi-spectral optical detection systems and methods. A light source (1) provides one or multiple lines (e.g., discrete wavelengths) of high spectral purity excitation light that is optically coupled to a sample via delivery fiber optic cables (3) . Emission light is collected and provided to an emission detector, such as a diffraction gradient spectrophotometer emission detector (7) , using collection fiber optic cables (5) bundled with the delivery fiber optic cables in a probe interface (8) positioned proximal a sample holder (4) . The probe interface may be scanned over one or more samples, or one or more samples may be scanned proximal a fixed interface probe. Multiple excitation wavelengths allows for simultaneous excitation and detection of multiple fluorescent dyes in the visible spectrum. This increases sample throughput and reduces signal variations associated with signal acquisition at different times. The optical system provides several advantages over other systems including higher sensitivity, improved compatibility with fluorescent dyes, better signal discrimination, increased system reliability and reduced manufacturing and service costs .

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10-07-1997 дата публикации

Continuous monitoring of physiological analyte

Номер: WO1997024059A1
Принадлежит: Cygnus, Inc.

A method for continual monitoring of a physiologic analyte in a subject includes steps of contacting the subject with a collection reservoir such that the analyte can move from the subject into the collection reservoir, the contents of the collection reservoir being in operative communication with a detector, collecting the analyte in the collection reservoir, using the detector to detect the analyte in the collection reservoir, and, once the analyte has been detected, rendering the analyte undetectable by the detector. Also, apparatus for continual monitoring of a physiologic analyte in a subject includes a collection reservoir for receiving the analyte from the subject, the contents of the collection reservoir being in operative relationship with a detector that detects the analyte in the reservoir, and means for rendering the analyte, once detected, undetectable by the reservoir.

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23-11-1999 дата публикации

Method for glucose sensing

Номер: US5989409A
Принадлежит: Cygnus Inc

A method for measuring the concentration of glucose diffused from a source to a working electrode which assembly includes a scavenging electrode is disclosed. The electrode of the invention is comprised of 1) a working electrode; 2) a scavenging electrode; 3) an electroosmotic electrode; and 4) a electrically insulating gap defined by adjacent edges of 1) and 2) and electrically isolating 1) and 2). The scavenging electrode substantially reduces or eliminates "edge-effects" or error in signal transported to the working electrode via a path which includes a radial vector component, i.e., eliminates chemical signal other than that which moves to the catalytic surface of the working electrode via a path which is substantially perpendicular to catalytic surface of the working electrode.

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07-04-1998 дата публикации

Chemical signal-impermeable mask

Номер: US5735273A
Принадлежит: Cygnus Inc

A chemical signal-impermeable mask is positioned in the electrolyte flow such that the mask is between a source of chemical signal and a working electrode which senses the chemical signal transported from the source (e.g., by diffusion). The configuration of the mask is such that the mask prevents substantially all chemical signal transport from the chemical signal source having a radial vector component relative to a plane of the mask and the catalytic face of the working electrode, thus allowing primarily only chemical signal transport that is substantially perpendicular to the place of the mask and the catalytic surface of the working electrode. By reducing or eliminating chemical signal radial transport toward the working electrode, the mask thus significantly reduces or eliminates edge effects. By substantially reducing edge effects created by radial transport of chemical signal, it is possible to obtain a more accurate measurement of the amount (e.g., concentration) of chemical signal that is transported from a given area of source material.

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30-01-2001 дата публикации

Method and device for predicting physiological values

Номер: US6180416B1
Принадлежит: Cygnus Inc

The invention relates generally to methods, systems, and devices for measuring the concentration of target analytes present in a biological system using a series of measurements obtained from a monitoring system and a Mixtures of Experts (MOE) algorithm. In one embodiment, the present invention describes a method for measuring blood glucose in a subject.

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31-10-2000 дата публикации

Chemical signal-impermeable mask

Номер: US6141573A
Принадлежит: Cygnus Inc

A chemical signal-impermeable mask is positioned in the electrolyte flow such that the mask is between a source of chemical signal and a working electrode which senses the chemical signal transported from the source (e.g., by diffusion). The configuration of the mask is such that the mask prevents substantially all chemical signal transport from the chemical signal source having a radial vector component relative to a plane of the mask and the catalytic face of the working electrode, thus allowing primarily only chemical signal transport that is substantially perpendicular to the place of the mask and the catalytic surface of the working electrode. By reducing or eliminating chemical signal radial transport toward the working electrode, the mask thus significantly reduces or eliminates edge effects. By substantially reducing edge effects created by radial transport of chemical signal, it is possible to obtain a more accurate measurement of the amount (e.g., concentration) of chemical signal that is transported from a given area of source material.

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22-07-2003 дата публикации

Device for signal processing for measurement of physiological analytes

Номер: US6595919B2
Принадлежит: Cygnus Inc

A method is provided for continually or continuously measuring the concentration of target chemical analytes present in a biological system, and processing analyte-specific signals to obtain a measurement value that is closely correlated with the concentration of the target chemical analyte in the biological system. One important application of the invention involves a method for signal processing in a system for monitoring blood glucose values.

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04-12-2001 дата публикации

Microprocessors for use in a device for predicting physiological values

Номер: US6326160B1
Принадлежит: Cygnus Inc

The invention relates generally to methods, systems, and devices for measuring the concentration of target analytes present in a biological system using a series of measurements obtained from a monitoring system and a Mixtures of Experts (MOE) algorithm. In one embodiment, the present invention describes a method for measuring blood glucose in a subject.

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15-05-2001 дата публикации

Signal processing for measurement of physiological analysis

Номер: US6233471B1
Принадлежит: Cygnus Inc

A method is provided for continually or continuously measuring the concentration of target chemical analytes present in a biological system, and processing analyte-specific signals to obtain a measurement value that is closely correlated with the concentration of the target chemical analyte in the biological system. One important application of the invention involves a method for signal processing in a system for monitoring blood glucose values.

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08-01-2002 дата публикации

Home hub for reporting patient health parameters

Номер: US6336900B1
Принадлежит: AGILENT TECHNOLOGIES INC

An apparatus for reporting a patient's health parameter to a remote data management center. The apparatus has measurement units and a home hub. A measurement unit includes a sensor for sensing measurements of a health parameter and a transmitter for transmitting wirelessly data derived from the measurements. The home hub receives the wireless transmission of measurement data, processes the measurement unit data for effecient transfer, and transmits selectively data processed by thereby via public a data transmission network to a health data management unit.

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23-10-2008 дата публикации

Method and device for predicting physiological values

Номер: US20080262334A1
Принадлежит: Animas Technologies LLC

The invention relates generally to methods, systems, and devices for measuring the concentration of target analytes present in a biological system using a series of measurements obtained from a monitoring system and a Mixtures of Experts (MOE) algorithm. In one embodiment, the present invention describes a method for measuring blood glucose in a subject.

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31-10-2000 дата публикации

Electrode with improved signal to noise ratio

Номер: US6139718A
Принадлежит: Cygnus Inc

An electrode assembly for sensing an electrochemical signal diffused from a source to a working electrode which is comprised of a plurality of substantially separated working electrode surfaces is disclosed. The electrode of the invention is comprised of 1) a working electrode made up of a plurality of working electrode surfaces or components and 2) a electrically insulating gap defined by adjacent edges of 1) insulating the working electrode surfaces or components from each other. The working electrode components are configured to receive electrochemical signal from two or preferably three dimensions simultaneously. The working electrode components configured over the same surface as a single electrode provide (1) an improved signal to noise ratio as compared to a single electrode by reducing noise, and (2) provide an overall enhanced signal after sensing for a given period of time.

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01-09-2022 дата публикации

TYK2 inhibitors and uses thereof

Номер: ES2921874T3
Принадлежит: Nimbus Lakshmi Inc

La presente invención proporciona compuestos, composiciones de los mismos y métodos de uso de los mismos para la inhibición de TYK2 y el tratamiento de trastornos mediados por TYK2. (Traducción automática con Google Translate, sin valor legal) The present invention provides compounds, compositions thereof, and methods of use thereof for the inhibition of TYK2 and the treatment of TYK2-mediated disorders. (Automatic translation with Google Translate, without legal value)

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17-07-2018 дата публикации

TYK2 inhibitors and uses thereof

Номер: US10023571B2
Принадлежит: Nimbus Lakshmi Inc

The present invention provides compounds of formula I, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.

Подробнее
03-05-2011 дата публикации

Terahertz frequency domain spectrometer with integrated dual laser module

Номер: US7936453B2
Принадлежит: Emcore Corp

An apparatus for analyzing, identifying or imaging a target including an integrated dual laser module coupled to a pair of photoconductive switches to produce CW signals in the range of frequencies from 100 GHz to over 2 THz focused on and transmitted through or reflected from the target; and a detector for acquiring spectral information from signals received from the target and using a multi-spectral homodyne process to generate an electrical signal representative of some characteristics of the target with resolution less than 250 MHz. The photoconductive switches are activated by laser beams from the dual laser module. The lasers in the module are tuned to different frequencies and have two distinct low frequency identification tones respectively that are used in conjunction with a stable optical filter element to permit precise determination of the offset frequency of the lasers.

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12-05-2015 дата публикации

Terahertz frequency domain spectrometer with phase modulation of source laser beam

Номер: US9029775B2
Принадлежит: Emcore Corp

An apparatus for analyzing, identifying or imaging an target including first and second laser beams coupled to a pair of photoconductive switches to produce CW signals in one or more bands in a range of frequencies greater than 100 GHz focused on, and transmitted through or reflected from the target; and a detector for acquiring spectral information from signals received from the target and using a multi-spectral heterodyne process to generate an electrical signal representative of some characteristics of the target. The lasers are tuned to different frequencies and a phase modulator in the path of one laser beam allows the constructive or destructive interference of the signals on the detector as the laser beams are swept in frequency to be adjusted to achieve greater resolution in one or more selected frequency bands.

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24-08-2010 дата публикации

Terahertz frequency domain spectrometer with controllable phase shift

Номер: US7781736B2
Принадлежит: Emcore Corp

An apparatus for analyzing, identifying or imaging an target including an integrated dual laser module coupled to a pair of photoconductive switches to produce cw signals in the range of frequencies from 100 GHz to over 2 THz focused on and transmitted through or reflected from the target; and a detector for acquiring spectral information from signals received from the target and using a multi-spectral homodyne process to generate an electrical signal representative of some characteristics of the target with resolution less than 250 MHz. The photoconductive switches are activated by laser beams from the dual laser module. The lasers in the module are tuned to different frequencies and a phase shifter in the path of one beam allows the beams to have an adjustable phase difference.

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10-12-2013 дата публикации

Terahertz frequency domain spectrometer with frequency shifting of source laser beam

Номер: US8604433B2
Принадлежит: Emcore Corp

An apparatus for analyzing, identifying or imaging an target including first and second laser beams coupled to a pair of photoconductive switches to produce CW signals in one or more bands in a range of frequencies greater than 100 GHz focused on and transmitted through or reflected from the target; and a detector for acquiring spectral information from signals received from the target and using a multi-spectral heterodyne process to generate an electrical signal representative of some characteristics of the target. The lasers are tuned to different frequencies and a frequency shifter in the path of one laser beam allows the terahertz beam to be finely adjusted in one or more selected frequency bands.

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26-07-2016 дата публикации

Terahertz frequency domain spectrometer with a single photoconductive element for terahertz signal generation and detection

Номер: US9400214B1
Принадлежит: Individual

There is described an apparatus for analyzing, identifying or imaging a target. The apparatus comprises a laser system which generates first and second laser beams having respective different frequencies, and directs the first and second laser beams along an optical path to a photoconductive material. An antenna structure is formed on the photoconductive material, the antenna structure comprises a first antenna for emitting electromagnetic radiation having a frequency dependent on the difference between said respective different frequencies of the first and second laser beams and a second antenna for generating a detection signal. A processor processes the detection signal to analyze, identify or image the target. The laser system is arranged such that the first and second laser beams overlap in a region of a surface of the photoconductive material having at least part of the first and second antennas formed thereon.

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02-10-1990 дата публикации

Bottom-unheading device and method for vertical vessels

Номер: US4960358A
Принадлежит: Foster Wheeler USA Corp

A bottom unheading device adapted for unheading vertical vessels such as coking drums. The unheading device includes a cover unit adapted for attachment to a lower flange of a coking drum and which is fastened by a plurality of swing bolts which are disconnected by remotely operated detensioning equipment, and a frame which can lower the cover unit and a carriage which moves it laterally to one side. A chute attached to the frame can be raised into engagement with the coking drum lower flange for removal of coke from the drum. Following such coke removal, the chute is lowered and the cover unit is moved laterally and remotely reconnected to the coking drum lower flange. The invention also discloses a method for remotely operating the unheading device.

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01-05-2001 дата публикации

Stud tensioning device for flange cover

Номер: US6223925B1
Принадлежит: Foster Wheeler Inc

A mechanism for selectively securing a cover to a flange of a pressure vessel. A plurality of such devices can be employed, using a plurality of studs that extend through matching openings in the flange and cover. A movable anchor plate or plates, also with holes through which each stud extends, is disposed adjacent to the flange or cover. The head of each stud will fit through its associated hole of the anchor plate (and into the opening of the closer one of the flange or cover) only if the anchor plate is properly oriented. When the anchor plate is so oriented, a piston head at the opposite end of the stud can be actuated away from the flange and cover to retract the stud head into the opening of the flange or cover. This protects the stud when the cover is disengaged from the flange. The stud can be biased in the opposite direction to permit the anchor plate to be reoriented into a position in which the stud head cannot pass through the anchor plate, so the stud can clamp the flange and cover together.

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22-06-2004 дата публикации

Modular pressure vessel unheading and containment system

Номер: US6751852B2
Принадлежит: Foster Wheeler USA Corp

An unheading and containment system for unheading and heading a pressure vessel includes an unheading apparatus for removing a cover from a pressure vessel in an unheading operation and a modular enclosure, mechanism to substantially enclose the cover during the unheading operation. The unheading apparatus includes a cover removably secured to the pressure vessel, a lock plate cooperating with the cover, and a cover moving mechanism capable of moving the cover vertically and laterally.

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04-01-2018 дата публикации

Vitreous cutter with integrated illumination system

Номер: AU2016291858A1
Принадлежит: Alcon Inc

An illuminated microsurgical instrument is provided herein that includes a microsurgical instrument having a tubular member arranged to treat patient tissue at a surgical site, the tubular member having a distal tip, an inner surface, and an outer surface. The inner surface defines a lumen. The outer surface has a notch formed therein. The illuminated microsurgical instrument further includes an optical fiber arranged to deliver light to the surgical site. The optical fiber includes a proximal end arranged to receive a light beam from a light source and also includes a curved distal end arranged to emit light adjacent to the distal tip. A portion of the curved distal end is positioned within the notch and curves away from the tubular member.

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08-01-2009 дата публикации

Systems and methods for determining cross-talk coefficients in pcr and other data sets

Номер: CA2691907A1

Systems and methods for determining cross-talk coefficients in curves, such as sigmoid-type or growth curves, and PCR curves and nucleic acid melting curves in particular, as well as for applying the cross-talk coefficients to produce cross-talk corrected data sets using a linear subtractive model. Cross-talk signal coefficients are determined using cross-talk data acquired across the entire signal acquisition range. Analyzing across all of the signal curve data provides for a more robust cross-talk correction across the entire data acquisition range. A linear subtractive model is used to correct data sets having cross-talk components.

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06-09-1983 дата публикации

Method and apparatus for forming a container for liquids

Номер: CA1153233A
Автор: Ronald T. Albo
Принадлежит: Individual

A CONTAINER FOR LIQUIDS Abstract of the Invention An apparatus and method is disclosed for forming a liquid-tight container having a rectangular cross-section formed from a one-piece, T-shaped blank of paperboard material. The carton preferably includes an access flap and straw element on one side thereof which, when manually lifted, exposes an end of the straw element from which the contents of the carton may be consumed by a user. The apparatus is compact in nature, possessing relatively few transport mechanisms which advance the T-shaped carton blank through a plurality of work stations. A novel method and apparatus for serially applying the straw element and access panel to the carton blank is disclosed, wherein the straw element and a length of polyethylene coated Mylar tape is automatically bonded to the carton blank upon a rotating heat sealing and alignment drum. A conveyor for collating a plural number of the carton blanks about a forming mandrel is also provided, and is positioned transversely to the remainder of the apparatus thereby significantly reducing the overall size of the apparatus. An ultrasonic welder bonds the side seams and end closure panels of the container upon a rotating crossbar mandrel which eliminates any misalignment during the sealing process. A substantially rigid conveyor transport carries a plurality of the carton blanks through pre-form, filler, and end closure work stations, and includes plural anvils for the ultrasonic welding process. An ejector mechanism is additionally provided which ejects the filled carton blanks from the rigid conveyor along a dual direction path, thereby eliminating the possibility of creasing or puncturing the filled and sealed container. The apparatus of the present invention additionally accommodates the production of differing size containers with only minor adjustments.

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29-12-2006 дата публикации

Flint/amber laminated glass container and method of manufacture

Номер: PT1127854E
Принадлежит: Owens Brockway Glass Container

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21-04-1987 дата публикации

Television receiver responsive to plural video signals

Номер: US4660085A
Принадлежит: RCA Corp

A television receiver is arranged to selectively display either information from a broadcast television signal, or information from an auxiliary video signal. The black image reference level associated with the broadcast signal information is sampled and used to automatically establish the black image reference level of the auxiliary video signal.

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16-05-2013 дата публикации

Multi-spot laser probe with faceted optical element

Номер: CA2853696A1
Принадлежит: Alcon Research LLC

In certain embodiments, a method includes forming a ferrule from a portion of a tube. The tube is cut to yield the ferrule and a short cannula. A multi-spot generator with a faceted optical element is added to the short cannula. An optical fiber is placed into the ferrule, and the ferrule and the short cannula are assembled. In certain embodiments, a system includes a long cannula, an optical fiber, and a multi-spot generator. The optical fiber can carry a laser beam to a distal end of the long cannula. The multi-spot generator is located at the distal end and comprises a faceted optical element and a ball lens. The faceted optical element can be formed directly onto or separately from the ball lens. The ball lens can be spherical or hemispherical.

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11-06-2013 дата публикации

Nuclease inhibitors and methods for their use

Номер: US8460684B2
Принадлежит: WISCONSIN ALUMNI RESEARCH FOUNDATION

A class of anionic oligomers and polymers that function for inhibition of nucleases, particularly RNase. Specific inhibitors include mixtures of oligomers of vinyl sulfate. Methods for inhibition or inactivation of one or more nucleases in vitro which comprises the step of contacting the one or more nucleases in a biological medium with one or more of the anionic oligomeric or polymeric inhibitors of this invention. Kits for carrying out a biological procedure, biological reaction and/or a biological assay containing one or more inhibitors of this invention. The use of oligomers and/or polymers of this invention as additives in buffers or reagents. The inhibitors of the invention can also be attached to surfaces to provide for removal of nucleases from media, solutions or other liquids in contact with the solid.

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10-12-2021 дата публикации

Aligning multi-wavelength laser beams with cores of a multi-core fiber

Номер: CA3139801A1
Принадлежит: Alcon Inc

Particular embodiments disclosed herein provide a surgical laser system comprising first laser source configured to emit a first laser beam with a first wavelength and a second laser source configured to emit a second laser beam with a second wavelength. The surgical laser system further comprises a first diffraction optical element (DOE) tuned to the first wavelength and a second DOE tuned to the second wavelength, wherein the first DOE is configured to diffract the first laser beam into one or more first diffracted beams at a diffraction angle and the second DOE is configured to diffract the second laser beam into one or more second diffracted beams at the same diffraction angle. The surgical laser system further comprises one or more beam splitters configured to reflect the one or more first diffracted beams and the one or more second diffracted beams onto a lens.

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23-02-2012 дата публикации

Terahertz frequency domain spectrometer with frequency shifting of source laser beam

Номер: CA2719217A1
Принадлежит: Emcore Corp

An apparatus for analyzing, identifying or imaging an target including first and second laser beams coupled to a pair of photoconductive switches to produce CW signals in one or more bands in a range of frequencies greater than 100 GHz focused on and transmitted through or reflected from the target; and a detector for acquiring spectral information from signals received from the target and using a multi-spectral heterodyne process to generate an electrical signal representative of some characteristics of the target. The lasers are tuned to different frequencies and a frequency shifter in the path of one laser beam allows the terahertz beam to be finely adjusted in one or more selected frequency bands.

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22-08-1990 дата публикации

Apparatus for dispensing a substance onto a crop material at a controlled rate

Номер: CA2010538A1
Принадлежит: Ford New Holland Inc

ABSTRACT OF THE DISCLOSURE Apparatus for dispensing a preservative or other substance, in solid or liquid form, onto a crop material being baled, the substance being dispensed onto the crop material before it is baled at a rate which is dependent on the moisture content of the crop material and the bulk rate of flow of crop material through the baler. The apparatus, which may be mounted on a square baler or a round baler, includes a first sensor for sensing the moisture content of the crop material and producing a first signal, a second sensor for producing an output signal indicative of the bulk rate of crop flow through the baler, and a control circuit responsive to the first signal and the second signal for producing a pulse width modulated signal for controlling the speed of a motor. The motor controls the rate at which the substance is dispensed from a container onto the crop material.

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13-11-1981 дата публикации

DEVICE FOR MAKING A CARDBOARD FLAN AN OPEN TUBULAR SHAPE

Номер: FR2482046A1
Принадлежит: Pneumatic Scale Corp

L'INVENTION CONCERNE LA FABRICATION DES RECIPIENTS ETANCHES AUX LIQUIDES. LE DISPOSITIF DESTINE A DONNER A UN FLAN DE CARTON 100 UNE FORME TUBULAIRE OUVERTE A SES EXTREMITES EST UTILISE DANS UN APPAREIL DE FABRICATION DE BOITES EN CARTON ETANCHES AUX LIQUIDES A PARTIR D'UN FLAN DE CARTON 100 POUVANT ETRE PLIE, AYANT UN MANDRIN 304 QUI PRESENTE UNE FORME EXTERIEURE DIMENSIONNEE POUR DONNER LA FORME TUBULAIRE SOUHAITEE AU FLAN 100. IL COMPORTE UN ENSEMBLE A MORS 360, SEPARE DU MANDRIN 304 ET ENTOURANT CE DERNIER, UN ELEMENT 279 POUR INSERER LE FLAN DE CARTON ENTRE L'ENSEMBLE A MORS360 ET LE MANDRIN 304 AFIN QUE LE FLAN 100 ENTOURE LE MANDRIN 304 SANS ETRE PLISSE, ET UN ELEMENT 370 DESTINE A FERMER L'ENSEMBLE A MORS 360 AUTOUR DU MANDRIN 304 POUR PLISSER LE FLAN 100 AUTOUR DU MANDRIN 304. DOMAINE D'APPLICATION: LA TECHNIQUE DE FABRICATION DES BOITES RENFERMANT, PAR EXEMPLE, DES BOISSONS, ETC. THE INVENTION RELATES TO THE MANUFACTURE OF LIQUID-TIGHT CONTAINERS. THE DEVICE INTENDED TO GIVE A BOARDBOARD BLANK 100 A TUBULAR SHAPE OPEN AT ITS ENDS IS USED IN AN APPARATUS FOR MANUFACTURING CARDBOARD BOXES WATERTIGHT TO LIQUIDS FROM A BOARDBOARD BLANK 100 THAT CAN BE FOLDED, HAVING A CORE 304 WHICH PRESENTS AN EXTERIOR SHAPE DIMENSIONED TO GIVE THE DESIRED TUBULAR SHAPE TO BLANK 100. IT INCLUDES A 360 JAW ASSEMBLY, SEPARATED FROM CHUCK 304 AND SURROUNDING THE LATTER, AN ELEMENT 279 TO INSERT THE CARDBOARD BLANK BETWEEN THE JAW ASSEMBLY 360 AND THE CHUCK 304 SO THAT THE BLANK 100 SURROUND THE CHUCK 304 WITHOUT BEING FOLDED, AND AN ELEMENT 370 IS INTENDED TO CLOSE THE ASSEMBLY WITH 360 JAWS AROUND THE CHUCK 304 TO FOLD THE BLANK 100 AROUND THE CHUCK 304. FIELD OF APPLICATION: THE MANUFACTURING TECHNIQUE BOXES CONTAINING, FOR EXAMPLE, BEVERAGES, ETC.

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06-02-1981 дата публикации

METHOD AND APPARATUS FOR FORMING A CONTAINER FOR LIQUIDS

Номер: FR2461647A1
Принадлежит: Pneumatic Scale Corp

L'INVENTION CONCERNE UNE MACHINE ET UN PROCEDE DE FABRICATION DE RECIPIENTS ETANCHES AUX LIQUIDES A PARTIR DE FLANS DE CARTON. CETTE MACHINE COMPORTE PLUSIEURS POSTES DE TRAVAIL: I A VIII DANS LESQUELS DES FLANS DE CARTON 100 RECOIVENT CHACUN UN CHALUMEAU ET UNE BANDE DE SCELLAGE, SONT PLIES, MIS EN FORME, FERMES A UNE EXTREMITE, REMPLIS D'UN LIQUIDE, FERMES A LEUR AUTRE EXTREMITE ET EJECTES. CES OPERATIONS SONT REALISEES SOIT SUR UN SEUL CARTON A LA FOIS LORSQU'ELLES DEMANDENT PEU DE TEMPS, SOIT SIMULTANEMENT SUR PLUSIEURS CARTONS LORSQU'ELLES SONT PLUS LONGUES, AFIN D'ACCROITRE LA PRODUCTIVITE DE LA MACHINE. DOMAINE D'APPLICATION: FABRICATION DE BOITES EN CARTON POUR BOISSONS, ETC. THE INVENTION CONCERNS A MACHINE AND A PROCESS FOR THE MANUFACTURING OF LIQUID-TIGHT CONTAINERS FROM CARDBOARD BLANKETS. THIS MACHINE INCLUDES SEVERAL WORKSTATIONS: IA VIII IN WHICH CARDBOARD BLANKS 100 EACH RECEIVE A TORCH AND A SEALING TAPE, ARE FOLDED, SHAPED, CLOSED AT ONE END, FILLED WITH A LIQUID, CLOSED AT THEIR OTHER END AND EJECTS. THESE OPERATIONS ARE CARRIED OUT EITHER ON A SINGLE BOX AT A TIME WHEN THEY REQUIRE A SHORT TIME, OR SIMULTANEOUSLY ON SEVERAL BOXES WHEN THEY ARE LONGER, IN ORDER TO INCREASE THE PRODUCTIVITY OF THE MACHINE. FIELD OF APPLICATION: MANUFACTURE OF CARTON BOXES FOR DRINKS, ETC.

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06-12-1991 дата публикации

THERMOPLASTIC COMPOSITION REDUCING CROSSING OF FLUIDS.

Номер: FR2662700A1
Автор: Ronald T Robichaud
Принадлежит: Greif Bros Corp

La présente invention concerne un additif thermoplastique contenant du stéarate d'aluminium et du fluorure de polyvinylidène qui, lorsqu'il est ajouté à des matières thermoplastiques telles que le polyéthylène, inhibe et réduit la traversée des fluides stockés dans les récipients composés de la matière thermoplastique. L'invention s'est révélée efficace pour réduire la traversée des matériaux à base d'hydrocarbure. The present invention relates to a thermoplastic additive containing aluminum stearate and polyvinylidene fluoride which, when added to thermoplastics such as polyethylene, inhibits and reduces the flow of fluids stored in containers composed of the thermoplastic material. . The invention has been found to be effective in reducing the penetration of hydrocarbon-based materials.

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04-07-1995 дата публикации

Dispersion-compensated windshield hologram virtual image display

Номер: CA2019742C
Автор: Ronald T. Smith
Принадлежит: Hughes Aircraft Co

A virtual image display including an image hologram, a dispersion compensating hologram for providing playback illumination to the image hologram, and an illumination source for providing playback illumination to the dis-persion compensating hologram.

Подробнее
04-04-1986 дата публикации

METHOD AND APPARATUS FOR FORMING A CONTAINER FOR LIQUIDS

Номер: FR2461647B1
Принадлежит: Pneumatic Scale Corp

Подробнее
02-07-1986 дата публикации

Spring-erected telescopic wing support structure

Номер: GB2115116B
Принадлежит: General Dynamics Corp

Подробнее
07-02-2008 дата публикации

Rfid ring illumination system for surgical machine

Номер: CA2658104A1
Принадлежит: Individual

An RFID ring illumination system includes an illumination ring and a printed circuit board. The illumination ring has a light refracting layer integral with the front of a surgical machine. The printed circuit board is located behind and close to the front of the surgical machine. The printed circuit board has an RFID reader antenna and a light source mounted on it. The light emitted by the light source travels through the illumination ring and is visible from the front of the surgical machine.

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29-12-2015 дата публикации

Surgical variable wide-angle illuminator

Номер: CA2827751C
Автор: Ronald T. Smith
Принадлежит: Alcon Inc

A variable-angle, wide-angle illuminator comprises: a light source providing a light beam; an optical cable for receiving/transmitting the light beam; a handpiece; an optical fiber to receive/transmit the light beam; an optical assembly for receiving the light beam and providing it to illuminate a surgical field; and a cannula for housing and directing the optical assembly. The optical assembly can comprise a fiber/polymer-dispersed-liquid-crystal ('PDLC') diffuser coupled to an optical needle or a nested compound parabolic concentrator cone. The light beam is emitted from the distal end of the optical fiber and provided to the PDLC diffuser and then a needle or fiber for transmission to the surgical site. The degree of diffusion of the light beam at the PDLC diffuser can be electrically controlled.

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24-11-1998 дата публикации

Thin rear combination lamp system

Номер: US5839813A
Автор: Ronald T. Smith
Принадлежит: Delco Electronics LLC

A vehicle exterior lamp system that includes a light source (11) for providing a plurality of beams, a plurality of optical fiber channels (17) responsive to the plurality of beams for providing a plurality of optical fiber channel outputs, a plurality of optical switches (15) for controlling the transmission of light by the plurality of optical fiber channels, and a plurality of rear exterior lamps (19) for projecting light received from the optical fiber channels to provide respective exterior lamp outputs.

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10-05-2007 дата публикации

Analytical multi-spectral optical detection system

Номер: CA2627914A1

Analytical multi-spectral optical detection systems and methods. A light source (1) provides one or multiple lines (e.g., discrete wavelengths) of high spectral purity excitation light that is optically coupled to a sample via delivery fiber optic cables (3) . Emission light is collected and provided to an emission detector, such as a diffraction gradient spectrophotometer emission detector (7) , using collection fiber optic cables (5) bundled with the delivery fiber optic cables in a probe interface (8) positioned proximal a sample holder (4) . The probe interface may be scanned over one or more samples, or one or more samples may be scanned proximal a fixed interface probe. Multiple excitation wavelengths allows for simultaneous excitation and detection of multiple fluorescent dyes in the visible spectrum. This increases sample throughput and reduces signal variations associated with signal acquisition at different times. The optical system provides several advantages over other systems including higher sensitivity, improved compatibility with fluorescent dyes, better signal discrimination, increased system reliability and reduced manufacturing and service costs .

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21-04-1987 дата публикации

Television receiver with selectable video input signals

Номер: US4660084A
Принадлежит: RCA Corp

A television receiver is arranged to selectively display either information from a broadcast television signal or information from an auxiliary video signal, in accordance with the position of a switching network to which the signals are capacitively coupled via respective capacitors. Similar black reference levels are established for the television and auxiliary signals by means of respective clamping circuits, including the coupling capacitors, which operate at different times but with respect to the same clamping reference voltage.

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22-08-1989 дата публикации

Process for forming an environmentally stable optical coating thereby

Номер: US4859492A
Принадлежит: Hughes Aircraft Co

An optical coating which is stable upon sustained exposure to water vapor is provided by a low-temperature photochemical vapor deposition process. First, there are provided a first vapor phase reactant containing silicon, a second selected vapor phase reactant, and an oxygen-containing precursor which are capable of interacting upon radiation inducement to form the corresponding oxides of the vapor phase reactants. A chosen substrate is exposed to the first and second selected vapor phase reactants in predetermined proportions and the chosen oxygen-containing precursor in the presence of radiation of a predetermined wavelength to induce a reaction to form a coating on the substrate. The coating comprises silicon dioxides containing a predetermined proportion of the second oxide, such as lead oxide. The coating maintains stable optical properties upon sustained exposure to water vapor. Graded index optical elements as well as quarterwave stack structure may be formed by this process.

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01-04-1999 дата публикации

Integrated wavelength-select transmitter

Номер: CA2303948A1

An integrated optical transmitter for use in an optical system has an optical head assembly with an optical beam generator for providing an optical beam and a lens assembly collecting the optical beam and generating therefrom a formed optical beam. Interface optics receive the formed optical beam and provide optical coupling so as to minimize insertion loss to the optical beam. Also included is an optical modulator for receiving the optical beam from the interface optics and for providing a modulated optical beam in response to received modulation signals. The optical modulator is coupled to the interface optics to be in a fixed relationship therewith.

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20-06-2007 дата публикации

Temperature step correction with double sigmoid levenberg-marquardt and robust linear regression

Номер: CA2571399A1
Автор: Ronald T. Kurnik
Принадлежит: F Hoffmann La Roche AG

Systems and methods for improving Ct determination in PCR amplification curves by correcting PCR data for temperature shifts that may occur during the PCR process. A double sigmoid function with parameters determined by a Levenberg-Marquardt (LM) regression process is used to find an approximation to the portion of the curve in the region after the temperature shift, termed "CAC", the cycle where the temperature shift occurred. A robust linear approximation is determined for the portion of the curve in the region before the temperature shift. Values of the fluorescent intensity for the cycle CAC or CAC+1 are determined using both the linear approximation and the LM process, and a difference in these values is subtracted off of the portion of the data set representing the portion of the curve before the temperature shift occurred to produce a shift-corrected data set. The shift-corrected data set may be displayed or otherwise used for further processing.

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22-06-2017 дата публикации

Diverging light from fiber optics illumination delivery system

Номер: CA3003373A1
Принадлежит: Mirsepassi Alireza, NOVARTIS AG

An illumination fiber optics is provided that includes an optical fiber, configured to receive illumination light at a proximal end from a light source; and a light-scattering element, at a distal end of the optical fiber, configured to receive the illumination light from the optical fiber at a proximal end and to emit the illumination light at a distal end in a wide angle. The illumination fiber optics can be prepared by providing an optical fiber, configured to receive illumination light at a proximal end from a light source; and creating a light-scattering element at a distal end of the optical fiber, configured to receive the illumination light from the optical fiber at a proximal end and to emit the illumination light at a distal end in a wide angle.

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26-11-1997 дата публикации

PC-controlled multimedia system and methods using the same

Номер: EP0809234A1
Автор: Ronald T. Taylor
Принадлежит: Cirrus Logic Inc

A television unit (110) containing a television display (130), a built-in personal computer (150) and a CD jukebox (140) for storing PC software, video disks and audio CDs. An operator controls the television unit by means of a user interface (120) containing a PC keyboard (124), a TV remote control keypad 126, and a joystick control or notepad (128). The user interface communicates with the television unit via a wireless infrared link.

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08-07-2014 дата публикации

Compact fiber optic gyroscope

Номер: US8773665B1
Принадлежит: Emcore Corp

A compact fiber optic gyroscope including a first housing; a transceiver module disposed in the first housing, the transceiver module including a second housing; a non-coherent light source disposed in the second housing for producing a first beam of light; a single lens for focusing the first beam of light; an optical circulator disposed in the second housing and in the path of the first beam of light to produce polarized second and third beams respectively, with polarization orthogonal to each other; and first and second photodiodes disposed in the second housing and coupled to the optical circulator, wherein the first photodiode is a transmit monitor photodiode coupled to the second beam, and the second photodiode is a receiver photodiode. The first housing further includes a planar optical fiber loop having a first end and a second end; a phase modulator coupled to the third beam emitted from the transceiver module to produce fourth and fifth beams coupled to the first and the second end respectively of the optical fiber loop respectively, and for receiving the return sixth and seventh beams from the second and the first ends respectively of the optical fiber loop.

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01-02-2004 дата публикации

Modular pressure vessel unheading and containment system

Номер: TW574485B
Принадлежит: Foster Wheeler Corp

Подробнее
30-10-2001 дата публикации

Annulated 4-carboxyamino-2-methyl-1,2,3,4-tetrahydroquinolines

Номер: US6310075B1
Принадлежит: PFIZER INC

Cholesteryl ester transfer protein inhibitors, pharmaceutical compositions containing such inhibitors and the use of such inhibitors to elevate certain plasma lipid levels, including high density lipoprotein-cholesterol and to lower certain other plasma lipid levels, such as LDL-cholesterol and triglycerides and accordingly to treat diseases which are exacerbated by low levels of HDL cholesterol and/or high levels of LDL-cholesterol and triglycerides, such as atherosclerosis and cardiovascular diseases in some mammals, including humans.

Подробнее
29-07-2003 дата публикации

Electrode with improved signal to noise ratio

Номер: CA2283240C
Принадлежит: Cygnus Inc

An electrode assembly for sensing an electrochemical signal diffused from a source to a working electrode which is comprised of a plurality of substantially separated working electrode surfaces is disclosed. The electrode of the invention is comprised of (1) a working electrode made up of a plurality of working electrode surfaces or components, and (2) an electrically insulating gap defined by adjacent edges of (1) insulating the working electrode surfaces or components from each other. The working electrode components are configured to receive electrochemical signal from two or preferably three dimensions simultaneously. The working electrode components configured over the same surface as a single electrode provide (1) an improved signal to noise ratio as compared to a single electrode by reducing noise, and (2) provided an overall enhanced signal after sensing for a given period of time.

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02-05-2012 дата публикации

Ophthalmic illuminator

Номер: EP1908395B1
Принадлежит: NOVARTIS AG

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11-07-2012 дата публикации

Ophthalmic illuminator

Номер: ES2384730T3
Принадлежит: Alcon Inc, NOVARTIS AG

Iluminador oftálmico (10), que comprende: una fuente de iluminación (14), en la que dicha fuente de iluminación produce un arco (55); una lente (23) para enfocar la luz (28) producida por el arco de la fuente de iluminación; y una fibra óptica (34) para llevar la luz enfocada a un lugar de cirugía en un ojo; caracterizado porque la fuente de iluminación está posicionada desplazada con respecto a un eje longitudinal de la fibra óptica, en una dirección hacia un ánodo de la fuente de iluminación, para compensar el cambio del arco de la fuente de iluminación con el paso del tiempo. Ophthalmic illuminator (10), comprising: a lighting source (14), wherein said lighting source produces an arc (55); a lens (23) to focus the light (28) produced by the arc of the light source; and an optical fiber (34) to bring the focused light to a surgical site in one eye; characterized in that the illumination source is positioned displaced with respect to a longitudinal axis of the optical fiber, in a direction towards an anode of the illumination source, to compensate for the change of the arc of the illumination source with the passage of time.

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14-02-1995 дата публикации

Automotive head-up display with high brightness in daytime and high contrast in nighttime

Номер: CA2013410C
Принадлежит: Hughes Aircraft Co

A head-up display having an image source for pro-ducing imaging illumination, an optical combiner for partially reflecting the imaging illumination to produce a virtual image of the image source that is viewable by the operator of the vehicle, and a polarizer which can be controllably interposed between the image source and the optical combiner for nighttime use. The polarizer tends to block the illumination that otherwise would produce objectionable ghost images.

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27-05-1988 дата публикации

An airframe having a self-erecting wing structure

Номер: HK36588A
Принадлежит: Gen Dynamics Corp

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10-03-2005 дата публикации

Alpha-ketoglutarate potentiators of insulin secretion

Номер: WO2005020977A1
Принадлежит: WISCONSIN ALUMNI RESEARCH FOUNDATION

The present invention relates to a recognition that an analog of αKG can increase glucose-induced insulin secretion in vitro and in vivo in animals, particularly in mammals, and more particularly in humans and in rodents. By employing the methods of the invention, insulin secretion can be increased.

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23-08-2022 дата публикации

Tyk2 inhibitors and uses thereof

Номер: CA2940666C
Принадлежит: Nimbus Lakshmi Inc

TYK2 is a non-receptor tyrosine kinase member of the Janus kinase (JAKs) family of protein kinases. The mammalian JAK family consists of four members, TYK2, JAK1, JAK2, and JAK3. JAK proteins, including TYK2, are integral to cytokine signaling. Disorders associated with TYK2 include autoimmune disorder, inflammatory disorder, proliferative disorder, endocrine disorder, neurological disorder, and disorder associated with transplantation. The present invention provides compounds exemplified by fommla I, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders. (see formula I)

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04-01-2017 дата публикации

Tyk2 inhibitors and uses thereof

Номер: EP3110820A1
Принадлежит: Nimbus Lakshmi Inc

The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.

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30-06-2015 дата публикации

Ophthalmic endoilluminators with directed light

Номер: US9066678B2
Принадлежит: Alcon Research LLC

Certain embodiments of an endoilluminator may include a cannula, an intermediate material, and an optical fiber. The cannula has a substantially cylindrical shape that defines an interior region and has a cylindrical axis. The intermediate material is disposed within the interior region. The optical fiber is disposed within the intermediate material and has a fiber optical axis and a distal end configured to emit light. The emitted light has an illumination pattern with an illumination axis that is not parallel to the cylindrical axis.

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08-10-1985 дата публикации

Process for forming a graded index optical material and structures formed thereby

Номер: US4545646A
Принадлежит: Hughes Aircraft Co

A process for depositing on the surface of a substrate a layer of a chosen material having continuous gradations in refractive index in a predetermined periodic pattern. The substrate is exposed to two vapor phase reactants which react upon radiation-inducement to produce the chosen material, and the relative proportion of the reactants is varied in a predetermined and continuous sequence to produce continuous gradations in the stoichiometric composition and refractive index of the deposited layer as a function of thickness. Additionally, predetermined changes in refractive index and/or thickness across the horizontal surface of the substrate may be produced in combination with the change in refractive index as a function of thickness. Diffraction optical elements formed by such a process include various optical filters and reflective optical coatings.

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