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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Форма поиска

Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 354. Отображено 104.
30-06-2005 дата публикации

Coriolis-Massendurchflussmessgerät

Номер: DE0010351311B3
Принадлежит: ABB PATENT GMBH

Coriolis-Massendurchflussmessgerät mit einem in gekoppelten Biege- und Torsionsmoden schwingenden Messrohr (2), dadurch gekennzeichnet, dass ein bezüglich einer Rotationssymmetrieachse drehsymmetrisch ausgebildetes, in Torsionsschwingungen gleicher Frequenz, aber entgegengesetzer Phasenlage zu den Torsionsschwingungsmoden des Messrohres (2) versetzbares Anbauteil (20) mechanisch mit dem Messrohr (2) verbunden ist und die Rotationssymmetrieachse des Anbauteils parallel zu der durch die Mittelpunkte (4a, 6a) der Messstreckeneinlass- und Messstreckenauslassquerschnittsflächen (4, 6) festgelegten Geraden (8) (Zentralachse) verläuft oder mit dieser zusammenfällt.

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12-04-2001 дата публикации

Abreisskopfschraube

Номер: DE0059800512D1

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21-02-2002 дата публикации

Verfahren und Vorrichtung zur Herstellung von Metallhydroxiden oder basischen Metallcarbonaten

Номер: DE0010030093C1
Принадлежит: STARCK H C GMBH, H.C. STARCK GMBH

Es wird ein Verfahren zur Herstellung von Metallhydroxiden oder basischen Metallcarbonaten durch anodische Auflösung entsprechender Metalle und Fällung der Hydroxide bzw. basischen Carbonate in wässrigem Medium beschrieben, bei dem die anodische Auflösung der Metallkomponente in der Anodenkammer einer Dreikammerelektrolysezelle erfolgt, der zwischen Anodenkammer und Kathodenkammer angeordneten und von diesen durch poröse Membranen abgetrennten Zwischenkammer kontinuierlich eine wässrige Hilfssalzlösung zugeführt wird, der Anodenkammer kontinuierlich eine mindestens nicht alkalische Metallsalzlösung entnommen wird, der Kathodenkammer kontinuierlich eine alkalische Hilfssalzlösung entnommen wird und die mindestens nicht alkalische Metallsalzlösung und die alkalische Hilfssalzlösung außerhalb der Elektrolysezelle zur Ausfällung von Metallhydroxiden bzw. basischen Metallcarbonaten vereinigt werden.

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22-06-2006 дата публикации

Steering column switch for motor vehicle, has elongated measuring unit attached at control lever so that lever deformation is measured by using control device in measuring unit during application of force, where device actuates switch

Номер: DE102005021681A1
Принадлежит:

The switch has a sensor device with an elongated measuring device. A control lever is designed such that the lever is selectively deformed by applying actuating force. The elongated measuring unit is attached at the lever so that the deformation of the lever is measured by using a control device utilized in the measuring unit during application of the force. The control device is provided for actuating the switch. The control lever is rigidly fixed at a steering column of the motor vehicle.

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01-11-2012 дата публикации

Method of Production of High-Strength Hollow Bodies from Multiphase Martensitic Steels

Номер: US20120273095A1
Принадлежит:

A method of production of high-strength hollow bodies from multiphase martensitic steels includes a heating process, a forming process and a cooling process. A heating device heats hollow steel stock to the austenitic temperature of the material from which the stock is made. The stock is then converted by deformation in a forming device into a hollow body having the final shape. A cooling device thereafter cools the hollow body such that the material with the original austenite microstructure refined by deformation during the forming process cools to a temperature at which incomplete transformation of austenite to martensite occurs. The retained austenite stabilization is performed in an annealing device by diffusion-based carbon partitioning within the material from which the hollow body is made. The hollow body is cooled in a cooling device to ambient temperature after stabilization. 1. A method of producing high-strength hollow bodies from multiphase martensitic steels , where the production includes a heating process , a forming process and a cooling process , comprising the steps of:heating a body of hollow steel stock to about an austenitic temperature of the material from which the stock body is made;converting the stock by deformation of the hollow steel stock body in a forming device into a hollow body having a final shape;initially cooling the hollow body having the final shape in an initial cooling device after the forming step in such a way that the material comprising the hollow body having a final shape and having an original austenite microstructure refined by deformation introduced during the forming step is initially cooled down to a temperature at which incomplete transformation of austenite to martensite takes place;annealing the initially cooled hollow body having a final shape in an annealing device whereby retained austenite stabilization is performed in the annealing device by diffusion-based carbon partitioning within the material from which ...

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01-11-2012 дата публикации

Method of Production of Steel Sheet Pressed Parts With Locally Modified Properties

Номер: US20120273096A1
Принадлежит:

According to the method of production of a steel sheet pressed part with locally modified properties, the steel sheet blank is first heated in a device for heating to the austenitic temperature of the material. Next, the steel sheet blank is converted in a tool for deep drawing by deformation into a final drawn part. Subsequently, the final drawn part is cooled inside the tool for deep drawing. Various locations of the final drawn part are cooled to various temperatures and/or at various rates during the cooling process. Thereafter, the final drawn part is placed in an annealing device, where retained austenite stabilization occurs by diffusion-based carbon partitioning within the material from which the drawn part is made. After stabilization, the final drawn part is removed from the annealing device and air cooled to ambient temperature. 1. A Method of production of a steel sheet pressed part with locally modified properties , comprising the steps of:heating the steel sheet blank in a heating device in a first production step to the austenitic temperature of the material from which the blank is made;thereafter converting the steel sheet blank in a tool for deep drawing by deformation into a final drawn part;thereafter initially cooling the final drawn part inside the tool for deep drawing such that various locations of the final drawn part are cooled to various temperatures and/or at various rates during the cooling step;thereafter placing the final drawn part in an annealing device and annealing the final drawn part under conditions whereby retained austenite stabilization takes place by diffusion-based carbon partitioning within the material from which the final drawn part is made; andafter the retained austenite stabilization is substantially competed, removing the final drawn part from the annealing device and then cooled down in a final cooling step in air to ambient temperature.2. Method of production of for making a steel sheet pressed part wherein after ...

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01-11-2012 дата публикации

IN-COLUMN DETECTOR FOR PARTICLE-OPTICAL COLUMN

Номер: US20120273677A1
Принадлежит: FEI COMPANY

The invention relates to an in-column back-scattered electron detector, the detector placed in a combined electrostatic/magnetic objective lens for a SEM. The detector is formed as a charged particle sensitive surface, preferably a scintillator disk that acts as one of the electrode faces forming the electrostatic focusing field. The photons generated in the scintillator are detected by a photon detector, such as a photo-diode or a multi-pixel photon detector. The objective lens may be equipped with another electron detector for detecting secondary electrons that are kept closer to the axis. A light guide may be used to offer electrical insulation between the photon detector and the scintillator. 1. A charged particle column comprising:a charged particle source for producing a beam of charged particles,a sample carrier for holding and positioning a sample, a first and a second electrode for generating a focusing electrostatic field, the first electrode positioned between the second electrode and the sample carrier, and', 'a first and a second pole piece for generating a focusing magnetic field, the first pole piece positioned between the second pole piece and the sample carrier,', 'the electrostatic field and the magnetic field showing overlap,, 'an objective lens for focusing the beam of charged particles on the sample, the objective lens having'}a detector at the source side of the first electrode for detecting charged particles, the detector showing a surface sensitive to charged particles,the second electrode shows an electrode surface facing to the sample carrier, andthe sensitive surface forms at least part of said electrode surface.2. The charged particle column of in which at least part of the second electrode is positioned between the first and the second magnetic pole piece claim 1 , and the first magnetic-pole piece coincides with the first electrode.3. The charged particle column of in which the sensitive surface is a scintillator claim 1 , and the ...

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04-04-2013 дата публикации

METHOD OF ACHIEVING TRIP MICROSTRUCTURE IN STEELS BY MEANS OF DEFORMATION HEAT

Номер: US20130081741A1
Принадлежит:

In a first step of the method of achieving TRIP microstructure in steels by deformation heat, steel feedstock is heated to a temperature below the temperature at which austenite begins to form in the steel in question, i.e. below A. In a next step, the feedstock is formed into a final product, using applied severe plastic deformation whereby deformation energy causes the temperature of the material to increase to the final temperature between Aand A, and whereupon the ferrite-pearlite microstructure transforms into austenite. In a third or last process step, the final product is cooled down from the final temperature to the temperature of the bainite nose of the material (B). The cooling is then interrupted and the material is held at the temperature of the bainite nose (B). Consequently, the TRIP microstructure forms. Finally, the product is cooled down to ambient temperature. 1. A method of achieving TRIP microstructure in steels by means of deformation heat comprising the steps of:heating steel feedstock to a temperature below the temperature at which transformation to austenite begins, the feedstock having a ferrite-pearlite microstructure;thereafter, forming the feedstock into a final product using severe plastic deformation, where the plastic deformation applies deformation energy to the feedstock which increases the feedstock's temperature to the final temperature between the temperature at which transformation to austenite begins and the temperature at which transformation to austenite is completed and whereupon a part of the ferrite-pearlite microstructure of the feedstock transforms into austenite;cooling the final product from the final temperature to a temperature within the bainite nose and held, which causes TRIP-type microstructure to form;cooling the final product down from the temperature within the bainite nose to ambient temperature.2. A method of achieving TRIP microstructure in steels by means of deformation heat according to wherein the ...

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02-05-2013 дата публикации

METHOD OF PRODUCTION OF PRESSED SHEET PARTS WITH INTEGRATED PREPARATION OF BLANKS OF NON-UNIFORM THICKNESS

Номер: US20130104616A1
Принадлежит:

A method of production of pressed sheet parts with integrated preparation of blanks of non-uniform thickness includes the steps of heating a steel sheet blank in heating equipment to the austenite region of the steel of the sheet steel blank in question, then forming the blank into a flat semi-finished product of non-uniform thickness in forming equipment, then immediately thereafter deep drawing the semi-finished product in deep drawing equipment into a final spatially shaped part. The method may further include cooling down the final spatially shaped part either during the drawing step or immediately after the deep drawing step in a manner which causes the final spatially shaped part to develop hardening microstructure, which imparts high strength to the final shaped part with non-uniform wall thickness. 1. A method of production of pressed sheet parts with integrated preparation of blanks of non-uniform thickness comprising the steps of:heating a steel sheet blank in heating equipment to the austenite region of the steel of the sheet steel blank;forming the blank into a flat semi-finished product of non-uniform thickness in forming equipment;thereafter deep drawing the semi-finished product in deep drawing equipment into a final spatially shaped part;cooling the final spatially shaped part either during the drawing step or immediately after the drawing step in a manner which causes it to develop hardening microstructure.2. The method of production of pressed sheet parts with integrated preparation of blanks of non-uniform thickness according to claim 1 , wherein the forming step includes rolling the blank and the flat semi-finished product is a sheet semiproduct of non-uniform thickness claim 1 , and including the step of hot straightening the the sheet semiproduct of non-uniform thickness in a roll straightener prior to the deep drawing step. 1. Field of the InventionThe present invention falls in the area of heat treatment and thermomechanical treatment of ...

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10-10-2013 дата публикации

Detection cell with controlled power dissipation

Номер: US20130267033A9
Автор: Gas Bohuslav, Witt Klaus
Принадлежит:

A voltage control circuitry for a detection cell () is described, whereby the detection cell () is adapted for determining an electrical property of a sample in a detection cell volume () of the detection cell (). The voltage control circuitry comprises a power supply () adapted for providing a voltage () to the detection cell (), and a power evaluation unit adapted for determining an actual power dissipation in the detection cell volume (). The voltage control circuitry further comprises a control unit () adapted for comparing the actual power dissipation with a desired power dissipation, and for regulating the power supply's voltage () in a way that the actual power dissipation is driven towards the desired power dissipation. 11121. A voltage control circuitry for a detection cell () , the detection cell () being adapted for determining an electrical property of a sample in a detection cell volume () of the detection cell () , the voltage control circuitry comprising{'b': 5', '6', '1, 'a power supply () adapted for providing a voltage () to the detection cell ();'}{'b': '2', 'a power evaluation unit adapted for determining an actual power dissipation in the detection cell volume ();'}{'b': 14', '6, "a control unit () adapted for comparing the actual power dissipation with a desired power dissipation, and for regulating the power supply's voltage () in a way that the actual power dissipation is driven towards the desired power dissipation."}2. The voltage control circuitry of claim 1 , wherein the control unit is adapted for determining a deviation between the actual power dissipation and the desired power dissipation claim 1 , and for regulating the power supply's voltage in a way that said deviation is minimized.3. The voltage control circuitry of or any one of the above claims claim 1 , wherein the detection cell is adapted for detecting an electrical property of a fluid sample.4. The voltage control circuitry of or any one of the above claims claim 1 , wherein ...

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17-10-2013 дата публикации

4-PHENYLAMINO-QUINAZOLIN-6-YL-AMIDES

Номер: US20130274275A1
Принадлежит:

This invention provides quinazoline compounds of the formula: 1. A method of treating non-small cell lung cancer in a mammal, the method comprising administering to the mammal in need thereof a pharmaceutically effective amount of This application is a divisional of U.S. application Ser. No. 12/754,556 filed Apr. 5, 2010, which is a divisional of U.S. application Ser. No. 11/122,345 filed May 5, 2005, now U.S. Pat. No. 7,772,243, which claims the benefit of U.S. Provisional Application Ser. No. 60/568,872, filed May 6, 2004, hereby incorporated by reference in their entireties.This invention relates to novel compounds which act as inhibitors of tyrosine kinases and are useful in methods of treating, preventing or inhibiting proliferative diseases, including cancer, atherosclerosis, restenosis, endometriosis and psoriasis. Particularly, this invention relates to novel 4-anilino-6-substituted alkenoylamino-quinazoline compounds useful in the treatment of such disorders.Substituted 4-phenylamino-quinazolin-6-yl-amides useful in the treatment of cancer have been described in the art, including those of U.S. Pat. No. 5,457,105 (Barker), U.S. Pat. No. 5,760,041 (Wissner et al.), U.S. Pat. No. 5,770,599 (Gibson), U.S. Pat. No. 5,929,080 (Frost), U.S. Pat. No. 5,955,464 (Barker), U.S. Pat. No. 6,251,912 (Wissner et al.), U.S. Pat. No. 6,344,455 (Bridges et al.), U.S. Pat. No. 6,344,459 (Bridges et al.), U.S. Pat. No. 6,414,148 (Thomas et al.), U.S. Pat. No. 5,770,599 (Gibson et al.), U.S. Pat. Appln. 2002/0173509 (Himmelsbach et al.), and U.S. Pat. No. 6,323,209 (Frost).There remains a need for novel and efficacious compounds for the treatment of proliferative disorders.This invention comprises quinazoline compounds of Formula I:wherein:Ris selected from F, Br, Cl or I;Ris selected from H, F, Br, Cl or I;Ris selected from:a) C-Cstraight or branched alkyl, optionally substituted by halogen; orb)-(CH)-morpholino, —(CH)-piperidine, —(CH)-piperazine, —(CH)-piperazine-N(C-Calkyl ...

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13-03-2014 дата публикации

Treatment of Cold Start Engine Exhaust

Номер: US20140072494A1
Принадлежит: Chevron U.S.A. INC.

The present invention relates to a process for reducing cold start emissions in an exhaust gas stream by contacting the exhaust stream with a combination of molecular sieves comprising (1) a small pore crystalline molecular sieve or mixture of molecular sieves having pores no larger than 8 membered rings selected from the group consisting of SSZ-13, SSZ-16, SSZ-36, SSZ-39, SSZ-50, SSZ-52 and SSZ-73 and (2) a medium-large pore crystalline molecular sieve having pores at least as large as 10 membered rings selected from the group consisting of SSZ-26, SSZ-33, SSZ-64, zeolite Beta, CIT-1, CIT-6 and ITQ-4. 1. A process for treating a cold-start engine exhaust gas stream containing hydrocarbons and other pollutants comprising flowing said engine exhaust gas stream over a combination of molecular sieves which preferentially adsorbs the hydrocarbons over water to provide a first exhaust stream , and flowing the first exhaust gas stream over a catalyst to convert any residual hydrocarbons and other pollutants contained in the first exhaust gas stream to innocuous products and provide a treated exhaust stream and discharging the treated exhaust stream into the atmosphere , the combination of molecular sieves comprising only an oxide (1) having a small pore crystalline molecular sieve selected from the group consisting of SSZ-13 , SSZ-16 , SSZ-36 , SSZ-39 , SSZ-50 , SSZ-52 , SSZ-73 and combinations thereof , and having a mole ratio of at least 10 of (a) an oxide of a first tetravalent element to (b) an oxide of a trivalent element , a pentavalent element , or a second tetravalent element which is different from said first tetravalent element or mixture thereof and an oxide (2) having a crystalline molecular sieve having pores at least as large as 12 membered rings and selected from the group consisting of SSZ-64 , zeolite Beta , CIT-1 , CIT-6 , ITQ-4 , and combinations thereof , and having a mole ratio of at least 10 of (a) an oxide of a first tetravalent element to (b) an ...

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09-01-2020 дата публикации

3D DEFECT CHARACTERIZATION OF CRYSTALLINE SAMPLES IN A SCANNING TYPE ELECTRON MICROSCOPE

Номер: US20200013581A1
Принадлежит:

The invention relates to a method 3D defect characterization of crystalline samples in a scanning type electron microscope. The method comprises Irradiating a sample provided on a stage, selecting one set of crystal lattice planes of the sample and orienting said set to a first Bragg condition with respect to a primary electron beam impinging on said sample, and obtaining Electron Channeling Contrast Image for an area of interest on the sample. The method is characterized by performing, at least once, the steps of orienting said selected set of crystal lattice planes to a further Bragg condition by at least tilting the sample stage with the sample by a user-selected angle about a first tilt axis, and obtaining by Electron Channeling Contrast Image for a further area of interest. 1. A method of 3D defect characterization of crystalline samples in a scanning type electron microscope , said scanning type electron microscope comprising:a sample stage for holding a sample;an electron source for producing a primary electron beam, as well as an illuminator having an electron-optical axis, wherein said electron microscope is arranged for directing said primary electron beam through the illuminator so as to irradiate said sample for producing an interaction that causes particle radiation to emerge from the sample, said radiation including backscattered electrons (BSEs); andat least one detector for detecting said BSEs;wherein said method comprises the step of:irradiating said sample provided on said stage;selecting one set of crystal lattice planes of the sample and orienting said set of crystal lattice planes to a first Bragg condition with respect to the primary electron beam impinging on said sample;obtaining by means of said at least one detector an Electron Channeling Contrast Image for an area of interest on the sample;{'b': '1', 'orienting said selected set of crystal lattice planes to a further Bragg condition, by at least tilting the sample stage about a first tilt ...

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23-01-2020 дата публикации

CYLINDER IN BOOM

Номер: US20200024829A1
Принадлежит:

Excavator having a stop positioned on a boom to protect a boom actuator from damage due to impact with an implement such as a blade, impact with handled material, or impact with other debris or objects. Boom actuators include an override device to allow the boom to be lowered in the event of an accident or component failure. 1. A power machine comprising:a frame comprising a lower frame portion and an upper frame portion, the upper frame portion rotatably mounted on the lower frame portion and configured to be rotated relative to the lower frame portion;a first lift arm structure having a boom pivotably coupled to the upper frame portion at a first pivot joint;a boom actuator pivotally coupled between the boom and the upper frame portion at a second pivot joint and operable to raise and lower the boom relative to the upper frame portion along a first path as the boom actuator raises and lowers the boom, the second pivot joint being positioned lower than the first pivot joint;a second lift arm pivotably coupled to the lower frame portion;a lower lift arm actuator coupled between the second lift arm and the lower frame portion and configured to raise and lower the second lift arm relative to the lower frame portion;an implement mounted to the second lift arm and configured to be raised and lowered with the lower lift arm by the lower lift arm actuator, a surface of the implement moving along a second path as the second lift arm is raised and lowered by the lower lift arm actuator, wherein the first path of the boom and the second path of the surface of the implement can intersect; anda stop positioned and oriented to receive contact between the boom and the surface of the implement as the boom moves along the first path and the surface of the implement moves along the second path to prevent contact between the boom actuator and the implement.2. The power machine of claim 1 , wherein the boom is pivotably coupled to the upper frame portion by a swing mount on the upper ...

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04-02-2021 дата публикации

METHOD OF PRODUCTION OF STEEL PARTS BY QUENCHING WITH TEMPERATURE EQUALIZATION AT MS

Номер: US20210032713A1
Принадлежит:

This invention generally relates to a method for producing steel parts by creating multiphase microstructures within the steel parts. Typically, the microstructures comprise low-stress martensite with increased ductility and stabilized retained austenite. The microstructures may be formed by cooling the steel parts to a temperature around the martensite start temperature (Ms) and subsequently holding the steel part at a temperature around the Ms in order to equalize the temperature throughout the steel part. Afterwards, the formation of the microstructures and the desired properties is completed by subjecting the steel part to a final cooling in still air. 1. A method for producing steel parts by creating a multiphase structure comprising low-stress martensite with increased ductility and stabilized retained austenite , wherein the method comprises: wherein the temperature of the surface of the steel part decreases by 5 to 50% of the interval between the Ms and martensite finish temperature (“Mf”),', 'wherein the temperature of the interior of the steel part is maintained above the Ms,, '(a) at least partially quenching a steel part in a quenching bath to thereby cool the surface of the steel part from a temperature in the austenite region to a temperature below the martensite start temperature (“Ms”),'}(b) equalizing temperature throughout the steel part to the Ms in equipment that maintains the Ms;(c) removing the steel part from the equipment; and(d) cooling the steel part to ambient temperature to thereby form a finished steel part comprising said multiphase structure.2. The method according to wherein claim 1 , during said quenching claim 1 , the steel part is repeatedly immersed in and removed from the quenching bath.3. The method according to wherein the temperature of the quenching bath is maintained at the Ms +/−50% of the interval between the Ms and Mf below the Ms for the steel part.4. The method according to wherein the quenching bath comprises a ...

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25-02-2021 дата публикации

METHOD OF PRODUCTION OF PARTS OF AHS STEEL BY CONTROLLED LOCAL COOLING BY A COOLING MEDIUM AND BY INTERRUPTED COOLING AT REQUIRED TEMPERATURE TO CREATE A MULTIPHASE MICROSTRUCTURE

Номер: US20210054470A1
Принадлежит:

This invention generally relates to a method for producing parts of AHS steel via a controlled local cooling by a cooling medium and an interrupted cooling at a required temperature, without immersion in a cooling bath, to thereby create a multiphase microstructure. Typically, the steel part may be cooled by a jet of cooling medium so that, depending on the amount of heat which needs to be removed from the surface of the part, the locations from which a larger amount of heat needs to be removed are cooled at a higher intensity. 1. A method for producing AHS steel parts , the method comprising:(a) cooling of a steel part at controlled locations by a jet of cooling medium at a first temperature; and(b) cooling the steel part at a designated temperature that is different from the first temperature to thereby create a multiphase microstructure, wherein the cooling of step (b) occurs at one or more intervals between the cooling of step (a),wherein the first temperature of the cooling of step (a) may be adjusted depending on the amount of heat that needs to be removed from a surface of the steel part.2. The method of according to claim 1 , wherein thin regions of the steel part that contain less steel material relative to thicker regions of the steel part that contain more steel material are cooled in a controlled fashion during the cooling of step (a) and the cooling of step (b) so that an undercooling temperature in the thin regions is higher than a minimum required cooling temperature.3. The method according to claim 1 , wherein a uniform temperature is maintained on the surface of the steel part.4. The method according to claim 1 , wherein the cooling of step (a) and the cooling of step (b) are affected by a nozzle. This application claims the foreign priority benefit of Czech Patent Application Serial No. PV 2019-542 entitled “METHOD OF PRODUCTION OF PARTS OF AHS STEEL BY CONTROLLED LOCAL COOLING BY A COOLING MEDIUM AND BY INTERRUPTED COOLING AT REQUIRED TEMPERATURE ...

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01-03-2018 дата публикации

CHARGED-PARTICLE MICROSCOPE WITH EXCHANGEABLE POLE PIECE EXTENDING ELEMENT

Номер: US20180061613A1
Принадлежит:

A charged-particle microscope having a vacuum chamber comprises a specimen holder, a particle-optical column, a detector and an exchangeable column extending element. The specimen holder is for holding a specimen. The particle-optical column is for producing and directing a beam of charged particles along an axis so as to irradiate the specimen. The column has a terminal pole piece at an extremity facing the specimen holder. The detector is for detecting a flux of radiation emanating from the specimen in response to irradiation by the beam. The exchangeable column extending element is magnetically mounted on the pole piece in a space between the pole piece and the specimen holder. Methods of using the microscope are also disclosed. 1. A charged-particle microscope having a vacuum chamber comprising:a specimen holder for holding a specimen;a particle-optical column for producing and directing a beam of charged particles along an axis so as to irradiate the specimen, the column having a terminal pole piece at an extremity facing the specimen holder;a detector for detecting a flux of radiation emanating from the specimen in response to irradiation by the beam; andan exchangeable column extending element magnetically mounted on the pole piece in a space between the pole piece and the specimen holder.2. A microscope according to claim 1 , wherein:a receiving face of the pole piece is provided with a first mechanical aligning feature; anda mating face of the extending element is provided with a second mechanical aligning feature;wherein the first and second mechanical aligning features engage with each other so as to cause the extending element to be held in a pre-defined position on the pole piece.3. A microscope according to claim 2 , wherein the pre-defined position is substantially centered on the axis.4. A microscope according to claim 2 , wherein:the receiving face is provided with a first set of utilities interconnects;the mating face is provided with a second, ...

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22-03-2018 дата публикации

METHOD OF PRODUCING HOLLOW OBJECTS AND AN ARRANGEMENT FOR SUCH METHOD

Номер: US20180078987A1
Принадлежит:

A method of, and arrangement for, producing shaped hollow metal objects by a hot process. A metal hollow semi-finished-product with at least one opening is heated to a forming temperature and placed into a cavity, whose shape corresponds to the desired final external shape of the hollow object. Then the cavity is sealed and water and/or steam is introduced therein. After the final shape of the semi-finished-product is achieved, the semi-finished-product is removed. The cavity is formed by a split mould, whose opening's entry edge has an expanded portion, against which a sealing feature is oriented. The outer surface of the sealing feature is arranged to close against this expanded portion. The sealing feature is also provided with a means of supply of water and/or steam, and a tube through which the water and/or steam is supplied. This tube extends into the interior space of the semi-finished-product, and can be provided with nozzles. 1. A method of producing shaped hollow objects of metals by a hot process , wherein a hollow semi-finished metal product (P) which is provided with at least one opening is heated to a forming temperature and placed into a cavity (D) , whose shape corresponds to the desired final external shape of the hollow object , after which the opening in the semi-finished product (P) is sealed and water and/or steam is introduced into the cavity (D) , and after the final shape of the semi-finished product (P) is achieved , the cavity (D) opens and the semi-finished product (P) is removed.2. The method of producing shaped hollow objects of metals by a hot process according to claim 1 , wherein after the temperature of the semi-finished product (P) becomes equal to the temperature of the mould (F) claim 1 , the semi-finished product (P) is removed from the mould (F) claim 1 , kept at this temperature for no less than 5 minutes and then cooled in air to ambient temperature.3. An arrangement for implementing the method according to claim 1 , wherein ...

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05-05-2022 дата публикации

MODIFICATION OF A DEEP-DRAWING SHEET BLANK FOR ELECTRIC RESISTANCE HEATING

Номер: US20220134406A1
Принадлежит:

The present invention generally relates to the modification of a deep-drawing sheet blank (P) for electric resistance heating. Generally, the modified sheet blank comprises slits (Z) being made in the edges of the blank (P) transversely to the electric current flow and oriented towards the perimeter of the forming zone (T). The distances between the ends of the slits (Z) and the forming zone (T) perimeter may be equal. The ends of the slits (Z) oriented towards the forming zone perimeter (T) may also be rounded.

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26-05-2016 дата публикации

Process and Installation for Producing a Press-Hardened Sheet Steel Component

Номер: US20160145707A1
Принадлежит: DAIMLER AG

A method and a system for producing a press-hardened sheet steel component is disclosed. The method includes: a) heating of a component blank formed from a hot-formable steel material at least to the austenitising temperature of the steel material by a heating device; b) hot forming of the component blank by a forming tool; c) cooling of the component blank in the forming tool to a temperature above the material-specific martensite finish temperature; d) bringing of the component blank from the forming tool to a warming device; and e) annealing of the component Hank, stabilizing the austenite in the component blank by the warming device. The component blank is brought directly from the forming tool to the waning device, preventing a cooling of the component Hank to less than the material-specific martensite finish temperature. 16-. (canceled)7. A method for producing a press-hardened sheet steel component , comprising the steps of:a) heating of a component blank formed from a hot-formable steel material at least to an austenitising temperature of the steel material by a heating device;b) hot forming of the component blank by a forming tool;c) cooling of the component blank in the forming tool to a temperature above a material-specific martensite finish temperature;d) bringing the component blank from the forming tool to a warming device; ande) annealing of the component blank by the warming device which stabilizes an austenite in the component blank;wherein the component blank is brought directly from the forming tool to the warming device preventing a cooling of the component blank to less than the material-specific martensite finish temperature.8. The method according to claim 7 , wherein the component blank is quenched in step e) in the forming tool to a temperature in a range from 200° C. to 500° C. inclusive.9. The method according to claim 7 , wherein the component blank is heated in step a) to a temperature between 800° C. and 1000° C.10. The method according ...

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05-08-2021 дата публикации

METHOD OF MANUFACTURING HYBRID PARTS CONSISTING OF METALLIC AND NON-METALLIC MATERIALS AT HIGH TEMPERATURE

Номер: US20210237417A1
Автор: MASEK Bohuslav
Принадлежит:

This invention generally relates to a method of manufacturing hybrid parts comprising metallic and non-metallic materials at high temperature. During the method, a hollow metallic feedstock heated to a temperature in the austenite region may be placed in a die and filled with a non-metallic material in a viscous condition, after which the feedstock in the die is formed and then controlled-cooled to cause hardening of the non-metallic material in the region of contact between the metallic and non-metallic material. Afterwards, the semi-finished product is removed from the die and cooled to room temperature. The rate of cooling may be adjusted to generate compressive stress in the surface layer of the non-metallic material, which reduces the risk of cracking. 1. A method of manufacturing hybrid parts comprising metallic materials and non-metallic materials , the method comprising:(a) heating a hollow feedstock of a metallic material to a temperature in the austenite region to thereby provide a heated hollow feedstock;(b) placing the heated hollow feedstock in a die;(c) filling the heated hollow feedstock with a non-metallic material in a viscous condition;(d) forming the heated hollow feedstock in the die to thereby provided a formed feedstock;(e) cooling the formed feedstock under controlled conditions to cause hardening of the non-metallic material in a region of contact between the metallic material and the non-metallic material to thereby form a semi-finished product;(f) removing the semi-finished product from the die to thereby provide a removed product; and(g) cooling the removed product to room temperature.2. The method of manufacturing hybrid parts according to claim 1 , wherein the cooling of step (e) is controlled to generate compressive stress in a surface layer of the non-metallic material to thereby reduce the risk of cracking.3. The method of forming hybrid parts according to claim 1 , wherein the non-metallic material comprises glass. This application ...

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03-08-2017 дата публикации

CHARGED-PARTICLE MICROSCOPE WITH ASTIGMATISM COMPENSATION AND ENERGY-SELECTION

Номер: US20170221673A1
Принадлежит: FEI COMPANY

A method of producing a corrected beam of charged particles for use in a charged-particle microscope, comprising the following steps: 1. A method of producing a corrected beam of charged particles for use in a charged-particle microscope , comprising:providing a non-monoenergetic input beam of charged particles; and a stigmator, thereby producing an astigmatism-compensated, energy-dispersed intermediate beam with a particular monoenergetic line focus direction; and', 'a beam selector, comprising a slit that is rotationally oriented so as to match a direction of the slit to said line focus direction, thereby producing an output beam comprising an energy-discriminated portion of said intermediate beam., 'passing said input beam through an optical module comprising a series arrangement of2. A method according to claim 1 , wherein:stigmator is used to mitigate a first, systematic astigmatism effect; andbeam selector is used to address a second, parasitic astigmatism effect.3. A method according to claim 2 , wherein;said first, systematic astigmatism effect is associated with eccentric lens traversal by said input beam; andsecond, parasitic astigmatism effect is associated with positioning errors in optical components upstream of the beam selector.4. A method according to claim 1 , wherein:beam selector comprises an opaque plate containing a plurality of slits of different orientations; andparticular slit is selected by effecting appropriate relative motion of said plate and said intermediate beam.5. A method according to claim 1 , wherein said beam selector comprises an opaque plate having a slit of adjustable orientation.6. A corrector device for use in a charged-particle microscope claim 1 , characterized in that it comprises:input for a non-monoenergetic input beam of charged particles; and stigmator, for producing an astigmatism-compensated, energy-dispersed intermediate beam with a particular monoenergetic line focus direction; and', 'beam selector, comprising a ...

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11-12-2014 дата публикации

METHOD FOR IMAGING A SAMPLE IN A CHARGED PARTICLE APPARATUS

Номер: US20140361165A1
Принадлежит: FEI COMPANY

The invention relates to a dual beam apparatus equipped with an ion beam column and an electron beam column having an electrostatic immersion lens. When tilting the sample, the electrostatic immersion field is distorted and the symmetry round the electron optical axis is lost. As a consequence tilting introduces detrimental effects such as traverse chromatic aberration and beam displacement. Also in-column detectors, detecting either secondary electrons or backscattered electrons in the non-tilted position of the sample, will, due to the loss of the symmetry of the immersion field, show a mix of these electrons when tilting the sample. 1. A method of imaging a sample in a charged particle apparatus , the charged particle apparatus comprising:an evacuable sample chamber,an electron beam column for producing a finely focused beam of electrons along an electron beam axis, said electron beam column equipped with an objective lens comprising an electrostatic immersion lens,a focused ion beam column for producing a finely focused beam of ions along an ion beam axis,the focused ion beam column and the electron beam column mounted on the sample chamber such that the electron beam axis and the ion beam axis intersect at an intersect position,a sample manipulator having a conductive plane equipped with means for holding the sample, the sample manipulator capable to tilt said plane between a first tilt angle in which the plane is perpendicular to the electron beam axis and a second tilt angle in which the plane is perpendicular to the ion beam axis, mounting the sample on the plane of the sample manipulator,', 'directing a beam of finely focused electrons to the sample with the electron beam column,', 'directing a beam of ions to the sample with the focused ion beam column,, 'the method comprising 'the electron beam column has an electrode closest to the intersect position and the focused ion beam column shows an electrode closest to the intersect position, said electrodes ...

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24-09-2020 дата публикации

EXCAVATOR BLADE CYLINDER

Номер: US20200299926A1
Принадлежит:

Disclosed embodiments include power machines with a lower implement pivotally coupled to an undercarriage frame by a lower lift arm structure and which include one or more cylinders or actuators that are operable to pivot the lower lift arm structure and lower implement relative to the undercarriage frame. A configuration of the one or more cylinders which mounts the cylinders behind the lower implement, with attachments to the undercarriage and to the lower lift arm structure at positions which allow the cylinders to be surrounded and protected by the undercarriage, reduces damage to the cylinders during operation. 1. A power machine comprising:a frame including an undercarriage;first and second tractive elements coupled to left and right sides of the undercarriage;a lift arm structure pivotally coupled to the undercarriage at a lift arm pivot;a first lift actuator pivotally coupled to the undercarriage at a first pivot and pivotally coupled to the lift arm structure at a second pivot, wherein the first and second pivots are positioned such that the first lift actuator is substantially surrounded by the undercarriage between a fully retracted and a fully extended position.2. The power machine of claim 1 , wherein the second pivot is positioned below the lower lift arm pivot.3. The power machine of claim 1 , wherein the first pivot is positioned rearward of a forward most position of the undercarriage such that claim 1 , when the first lift actuator is fully extended claim 1 , at least fifty percent of the length of first lift actuator is positioned rearward of the forward most position of the undercarriage.4. The power machine of claim 3 , wherein the first pivot and second pivot are positioned such that claim 3 , when the first lift actuator is fully extended claim 3 , substantially all of the first lift actuator is positioned rearward of the forward most position of the undercarriage.5. The power machine of claim 1 , wherein the lift arm structure includes a ...

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26-11-2015 дата публикации

MICROSTRUCTURE OF HIGH-ALLOY STEEL AND A HEAT TREATMENT METHOD OF PRODUCING THE SAME

Номер: US20150337417A1
Принадлежит:

A method of producing a microstructure of a high-alloy steel includes heating the metal stock to a temperature between 1270° C. and 1280° C., at a rate between 40° C./s and 45° C./s, followed by compression applied to the metal stock in a thixotropic process, after which the stock is cooled to ambient temperature. A microstructure is also shown, which includes undissolved metal carbides in the form of globular particles of austenite microstructure and of martensite microstructure. 1. Microstructure of a high-alloy steel characterized by its content of undissolved metal carbides in the form of globular particles in the range of 10 wt. %-25 wt. % , 40 wt. %-50 wt. % austenite microstructure and 10 wt. %-25 wt. % martensite microstructure.2. A method of producing the microstructure of a high-alloy steel in characterized by heating the metal stock to a temperature between 1270° C. and 1280° C. at a rate between 40° C./s and 45° C./s claim 1 , after which compression is applied to the metal stock in a thixotropic process claim 1 , after which the stock cools to ambient temperature.3. A method of producing the microstructure of a high-alloy steel in characterized by the use of thixoforming after heating to a temperature between 1270° C. and 1280° C. This application claims the benefit of Czech Republic Application No. PV2014-348 filed May 24, 2014, the entire disclosure of which is incorporated herein by reference.The present invention relates to a microstructure of a high-alloy steel in so small parts and a heat treatment method of producing such microstructure.In literature, the term high-alloy steels is used for steels which contain alloying elements at a total level of more than 10%. By means of alloying elements, the required mechanical, physical and chemical properties are achieved. Properties of such steels depend not only on chemical composition but mainly on microstructure, i.e. on the phase composition and on the shape and configuration of individual phases. The ...

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31-12-2015 дата публикации

METHOD OF MANUFACTURING HOT DEEP DRAWN STEEL PARTS OF SHEET METAL

Номер: US20150375286A1
Принадлежит:

The invention relates to a method of manufacturing steel parts of sheet metal by hot deep drawing characterized by bringing the semi-finished product into austenitic condition by heating, subsequently cooling its locations, which would undergo undesirable deformation, to a temperature below the austenite temperature, and then completing the forming process. 1. A method of manufacturing steel parts by the method of hot deep drawing of steel sheet metal blank characterized by heating the blank to bring it into austenitic condition and subsequently cooling its locations which would undergo undesirable deformation to a temperature below the austenite temperature and then completing the forming process.2. A method of manufacturing steel parts as claimed in characterized by cooling the critical-deformation locations of the sheet metal blank after it was heated to austenitic condition and before it is placed into the forming tool.3. A method of manufacturing steel parts as claimed in characterized by cooling the semi-finished product after heating to austenitic condition after placing into the forming tool. This application claims the benefit of Czech Republic Application No. PV2014-455 filed Jun. 30, 2014, the entire disclosure of which is incorporated herein by reference.This invention relates to a method of manufacturing steel parts of sheet by hot deep drawing.At present, hot-formed steel parts made by deep drawing and subsequent cooling in the tool are made by heating a sheet metal blank of suitable dimensions in a furnace to the austenite temperature, holding for several minutes, then removing the sheet metal blank from the furnace and transferring it to a tool, in which deep drawing is carried out. This pressed part cools when it comes into contact with the tool, which causes transformation to a microstructure, which is typically or hardening type, i.e. martensite, bainite or mixed-type. This method is used, for instance, in the patent file no. U.S. Pat. No. 4,619, ...

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12-12-2019 дата публикации

MULTI-BEAM ELECTRON MICROSCOPE

Номер: US20190378681A1
Принадлежит: FEI COMPANY

An electron microscope comprising:

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26-12-2019 дата публикации

MULTI-BEAM CHARGED PARTICLE IMAGING APPARATUS

Номер: US20190393013A1
Принадлежит: FEI COMPANY

A charged particle imaging apparatus comprising: 1. A charged particle imaging apparatus comprising:a specimen holder, for holding a specimen; and produce a plurality of charged particle beams, by directing a progenitor charged particle beam onto an aperture plate having a corresponding plurality of apertures within a footprint of the progenitor charged particle beam; and', 'direct the plurality of charged particle beams toward said specimen;, 'a particle-optical column, configured to said aperture plate comprises a plurality of different zones arranged within said progenitor charged particle beam footprint, wherein the each of the plurality of different zones comprise mutually different aperture patterns; and', 'the particle-optical column comprises a selector device, located downstream of said aperture plate, wherein the selector device is configured to select a beam array from a chosen zone of the plurality of different zones to be directed onto the specimen., 'characterized in that2. An apparatus according to claim 1 , wherein at least two of said plurality of different zones have an essentially identical aperture distribution.3. An apparatus according to claim 1 , wherein one of said plurality of different zones comprises a singular through-hole claim 1 , configured to allow passage of a portion of said progenitor charged particle beam without subdividing it.4. An apparatus according to claim 3 , wherein at least one of a variable opening in said selector device claim 3 , and an adjustable lens assembly disposed between said aperture plate and said selector device claim 3 , is used to curtail a beam current value of a beam passing through said singular through-hole in said aperture plate.5. An apparatus according to claim 1 , wherein said selector device comprises a masking plate with a restrictive opening that can be positioned so as to allow only the selected beam array from the chosen zone to pass to the specimen.6. An apparatus according to claim 5 , ...

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11-02-1992 дата публикации

Photopolymerizable compositions containing inorganic fillers

Номер: CA1295761C
Автор: Berhan Tecle
Принадлежит: EI Du Pont de Nemours and Co

TITLE PHOTOPOLYMERIZABLE COMPOSITIONS CONTAINING INORGANIC FILLERS ABSTRACT Improved performance in photopolymerizable compositions has been obtained by mixing inorganic filler with polymeric binder prior to incorporation of monomer. 4110k

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31-01-1990 дата публикации

Photopolymerizable compositions containing inorganic fillers

Номер: EP0259812A3
Автор: Berhan Tecle
Принадлежит: EI Du Pont de Nemours and Co

Improved performance in photopolymerizable compositions has been obtained by mixing inorganic filler with polymeric binder prior to incorporation of monomer.

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03-02-1998 дата публикации

Pigmented ink set and process for alleviating bleed in printed elements using carboxylic acid additives

Номер: US5713993A
Принадлежит: EI Du Pont de Nemours and Co

Bleed between two adjacent pigmented inks on a printing medium is reduced. The first ink has at least one neutralized carboxylic acid group, neutralized amine, or a quaternized amine group; and the second ink contains a polymeric dispersant having at least one sulfonate or phosphonate group, and a carboxylic acid additive having a pKa of up to 3.5.

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21-12-1999 дата публикации

Ink jet inks containing branched polymer dispersants and emulsion polymer additives

Номер: US6005023A
Принадлежит: EI Du Pont de Nemours and Co

An ink for ink jet printers contains an aqueous carrier medium; a colorant that is insoluble in the aqueous carrier; a branched polymer dispersant; and an emulsion polymer additive and is stable, has low viscosity, exhibits excellent print quality, provides excellent smear resistance after drying and has good decap or crusting time.

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13-01-1998 дата публикации

Graft copolymers containing sulfonate and phosphonate groups having particular utility as pigmented ink dispersants

Номер: US5708095A
Принадлежит: EI Du Pont de Nemours and Co

A graft polymer having (a) a hydrophilic backbone prepared from unneutralized acid containing monomers wherein the acid has a pKa of at least 3, and wherein the backbone is completely soluble in water and insoluble in non-polar organic solvents; and (b) at least one discrete hydrophobic side chain, wherein 20 to 100% of the side chains are prepared from non-polar aliphatic or aromatic monomers having a chain length of at least 4 carbon atoms; wherein the side chains are attached to the backbone at a single terminal point and wherein the at least one discrete hydrophobic side chain has a weight average molecular weight of 1000 to 30,000. These graft polymers are useful as dispersants in aqueous solutions, particularly in ink jet inks.

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29-05-1990 дата публикации

Tetrahydropyridine oxime compounds

Номер: US4929734A
Принадлежит: Warner Lambert Co LLC

Certain N-substituted 1-(1,2,3,6-tetrahydro-3-pyridinyl)oximes and N-substituted 1-(1,2,3,6-tetrahydro-4-pyridinyl)oximes are useful as sigma binding agents for the treatment of depression, psychoses and/or inflammatory diseases.

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03-02-2004 дата публикации

Paint, and a method of producing same

Номер: SK13572003A3
Принадлежит: Moles Technology, A. S.

A paint has a film-forming binder component, a color-producing component, and a fire-retardant component adapted to least substantially protect from fire a surface of which the paint is applied; and the paint is produced by a method including providing a film-forming binder component; providing a color-producing component; mixing the components with some of dried powder components missing; and adding a fire retardant component to replace the dry powder component.

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04-11-2003 дата публикации

Oxygenated esters of 4-iodo phenylamino benzhydroxamic acids

Номер: SK422003A3
Принадлежит: Warner Lambert Co

The present invention relates to oxygenated esters of 4-iodophenylamino benzhydroxamic acid derivatives, pharmaceutical compositions and methods of use thereof. The present invention also relates to crystaline forms of oxygenated esters of 4-iodophenylamino benzhydroxamic acid derivatives, pharmaceutical compositions and methods of use thereof.

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03-02-2005 дата публикации

N-methyle-substituted benzamidazoles

Номер: CA2532067A1

The present invention relates to N-methyl-substituted benzamidazole derivatives of formula (I), as defined in the specification; pharmaceutical compositions and mehtod of use thereof,as inhibitors of MEK.

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27-12-2005 дата публикации

4-bromo or 4-iodo phenylamino benzhydroxamic acid derivatives and their use as mek inhibitors

Номер: CA2290506C
Принадлежит: Warner Lambert Co LLC

Phenylamino benzhydroxamic acid derivatives of formula (I) where R1, R2, R3, R4, R5, and R6 are hydrogen or substituent groups such as alkyl, and where R7 is hydrogen or an organic radical, are potent inhibitors of MEK and, as such, are effective in treating cancer and other proliferative diseases such as psoriasis and restenosis.

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07-02-1928 дата публикации

Improvements to facilities for extracting gold from seawater

Номер: FR633998A
Принадлежит:

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05-03-1976 дата публикации

MATERIAL FOR BATTERY SEPARATORS

Номер: FR2281651A1
Принадлежит: CARL FREUDENBERG KG

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24-03-1989 дата публикации

GEARBOX MECHANISM

Номер: FR2556292B1
Принадлежит: Ustav Pro Vyzkum Motorovych Vozidel

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27-11-1984 дата публикации

Iron-on interfacing material

Номер: CA1178524A
Принадлежит: CARL FREUDENBERG KG

ABSTRACT An iron-on padding or interfacing material made of a non-woven textile comprising a plurality of layers of gauze on one another. Each layer comprises randomly disposed and/or parallel staple fibres, and/or continuous fibres. The individual layers are internally and mutually bonded by bonding agents or bonding fibres. A thermoplastic adhesive is applied to at least one side of the material as a pattern, the gauze layer on that one side having the smallest quantity of bonding agent or bonding fibres. The bonding fibres may be thermo-plastic and may be bi-component fibres of Nylon 66/Nylon 6, polyethylene-terephthalate/polybutylene-terephthalate, and polyethylene-terephthalatetco-polyester.

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29-05-1984 дата публикации

Spot bonded pattern for non-woven fabrics

Номер: US4451520A
Принадлежит: CARL FREUDENBERG KG

This application relates to a non-woven fabric wherein the fibers of the fabric are bonded to each other and/or to another material in a plurality of equally spaced-apart spots, wherein the spots are the same size and are combined in a plurality of identical groups of not less than three nor more than five identical spots, each of said groups of spots being spaced apart from each other, and each of said spots within each group being positioned along a curved or straight line wherein the steady extension of said line beyond the end-spots of said group positioned along said line intersects and adjacent line along which an adjacent group of spots is positioned, and wherein the ratio of the distance separating the spots within each group of spots to the distance from an end-spot in each group to the next adjacent line along which an adjacent group of spots is positioned, is about 0.5 to about 3.0.

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09-07-1991 дата публикации

Substituted tetrahydro-3-pyridine-carboxylic acid, ester and amide cholinergic agents

Номер: CA1285939C
Принадлежит: Warner Lambert Co LLC

Abstract Certain substituted 1,2,3,6-tetrahydro- and 1,2,5,6-tetrahydropyridine-3-carboxylic acids, esters, and amides possessing muscarinic binding activity, having utility for the treatment of the symptoms of senile cognitive decline disclosed. Pharmaceutical compositions and a pharmaceutical method of treatment are also disclosed.

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17-05-1988 дата публикации

Substituted tetrahydro-3-pyridine-carboxylic acid, ester, and amide cholinergic agents

Номер: US4745123A
Принадлежит: Warner Lambert Co LLC

Certain substituted 1,2,3,6-tetrahydro- and 1,2,5,6-tetrahydropyridine-3-carboxylic acids, esters, and amides possessing muscarinic binding activity, having utility for the treatment of the symptoms of senile cognitive decline disclosed. Pharmaceutical compositions and a pharmaceutical method of treatment are also disclosed.

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13-05-2003 дата публикации

Azabicyclo arylacetylene and arylenyne oximes as cholinergic agents and methods of treatment

Номер: CA2115443C
Принадлежит: Warner Lambert Co LLC

Pharmaceutically useful nitrogen containing cyclic oxime substituted compounds which are arylacetylene and arylenyne azabicyclo (2.2.1] oximes of formula (I) which are useful for alleviating pain and for treating cognitive decline are described; pharmaceutical compositions and a method of manufacture are also described. In formula (I), R is selected from the group (IIa) and (IIb).

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07-08-2003 дата публикации

2-(4-bromo or 4-iodo phenylamino) benzoic acid derivatives

Номер: US20030149015A1
Принадлежит: Individual

Phenylamino benzoic acid, benzamides, and benzyl alcohol derivatives of the formula where R 1 , R 2 , R 3 , R 4 , R 5 , and R 6 are hydrogen or substituent groups such as alkyl, and where R 7 is hydrogen or an organic radical, and Z is COOR 7 , tetrazolyl, CONR 6 R 7 , or CH 2 OR 7 , are potent inhibitors of MEK and, as such, are effective in treating cancer and other proliferative diseases such as inflammation, psoriasis and restenosis, as well as stroke, heart failure, and immunodeficiency disorders.

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10-07-2013 дата публикации

Method of achieving TRIP microstructure in steels by deformation heat

Номер: CZ2011612A3
Принадлежит: Západoceská univerzita v Plzni

Popisuje se zpusob dosazení TRIP struktury ocelí s vyuzitím deformacního tepla, kde v prvním kroku je ocelový polotovar ohrát na teplotu lezící pod pocátkem austenitizace dané oceli, tedy pod teplotu (Ac.sub.1.n.). V dalsím kroku je polotovar zpracován tvárením s intenzivní plastickou deformací na výsledný produkt. V prubehu intenzívní plastické deformace dojde pomocí deformacní energie ke zvýsení teploty na koncovou teplotu lezící v rozmezí mezi teplotami (Ac.sub.1.n.) a (Ac.sub.3.n.), címz dojde k cástecné transformaci fereticko-perlitické struktury na austenit. V posledním kroku je výsledný produkt z koncové teploty ochlazen na teplotu odpovídající pocátku bainitického nosu (B). Na teplote odpovídající pocátku bainitického nosu (B) je provedena prodleva v procesu ochlazování, címz dojde ke vzniku TRIP struktury. V záveru je výsledný produkt vychlazen na teplotu okolí. There is described the method of the TRIP structure of steels using deformation heat, where in the first step the steel semifinished product is brought to the temperature crawling under the beginning of austenitization of the steel, ie below the temperature (Ac.sub.1.n.). In the next step, the semi-finished product is processed by forming with intensive plastic deformation into the final product. During the intense plastic deformation, the deformation energy causes the temperature to rise to the end temperature between the temperatures (Ac.sub.1.n) and (Ac.sub.3), whereby a feretico-pearlitic transformation occurs. structures on austenite. In the final step, the resulting product is cooled from the end temperature to a temperature corresponding to the start of the bainite nose (B). At the temperature corresponding to the beginning of the bainite nose (B), there is a delay in the cooling process, whereby a TRIP structure is formed. In conclusion, the resulting product is cooled to ambient temperature.

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21-04-1982 дата публикации

Iron-adhesive interlining fabric

Номер: EP0049732A1
Принадлежит: CARL FREUDENBERG KG

Die Erfindung betrifft einen aufbügelbaren Einlagevliesstoff aus mehreren aufeinander abgelegten Lagen von Floren. Die einzelnen Lagen sind in sich und untereinander durch Bindefasern gebunden und auf wenigstens einer der Oberflächen ist ein Schmelzkleber musterförmig aufgetragen. Die verschiedenen Flore enthalten unterschiedliche Mengenanteile Bindefasern. The invention relates to an iron-on interlining nonwoven fabric composed of a plurality of layers of pile placed on top of one another. The individual layers are bound in and among themselves by binding fibers and a hot melt adhesive is applied in a pattern on at least one of the surfaces. The different piles contain different proportions of binding fibers.

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20-07-2000 дата публикации

1-heterocycle substituted diarylamines

Номер: CA2355374A1
Принадлежит: Individual

1-Heterocycle substituted diarylamines, methods of making and using them, and compositions containing them.

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10-11-2011 дата публикации

Drilled underground gaseous storage system

Номер: US20110274492A1
Принадлежит: Texaco Inc

The present invention discloses embodiments of a drilled underground gaseous storage system. The embodiments of the present invention comprise storage tubes inserted below the surface of the ground for the storage of gases. The embodiments of the present invention may be used to store gaseous hydrogen. In addition, the embodiments of the present invention many be used to store other gases such as compressed natural gas.

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27-02-2004 дата публикации

1-heterocycle substituted diarylamines

Номер: NZ513432A
Принадлежит: Warner Lambert Co

Подробнее
15-12-1982 дата публикации

Process for bonding non-woven fabrics

Номер: EP0012776B1
Принадлежит: CARL FREUDENBERG KG

Подробнее
30-09-2008 дата публикации

Benzoheterocycles and their use as mek inhibitors

Номер: CA2355470C
Принадлежит: Warner Lambert Co LLC

The invention provides compounds having formula (I), (see formula I) wherein W is OH, or derivatives of the carboxylic acid, and Q is a heterocyclo-condensed ortho-phenylene residue. These compounds are useful as MEK inhibitors, particularly in the treatment of proliferative diseases such as cancer.

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16-03-1989 дата публикации

IMPROVED PROCEDURE FOR PREPARING PULP TO MAKE PAPER.

Номер: ES2005527A4
Автор: Bohuslav V Kokta
Принадлежит: Stake Technology Ltd

ESTA INVENCION SE REFIERE A UN PROCEDIMIENTO MEJORADO PARA PREPARAR PULPA ADECUADA PARA FABRICAR PAPEL. AUNQUE EN EL PASADO SE HABIAN CONOCIDO PROCEDIMIENTOS QUE UTILIZAN DESCOMPRESION EXPLOSIVA, SE HA CREIDO QUE ESTOS TIENEN QUE LLEVARSE A CABO A TEMPERATURAS RELATIVAMENTE BAJAS. AUNQUE TALES PROCEDIMIENTOS CONOCIDOS DE DESCOMPRESION EXPLOSIVA PRODUCIAN UN AHORRO DE ENERGIA, LA RESISTENCIA FISICA ERA BAJA, EL COLOR ERA RELATIVAMENTE OSCURO, Y HABIA UNA CONSIDERABLE PERDIDA DE RENDIMIENTO. ESTA INVENCION PROPORCIONA UN PROCEDIMIENTO PARA CONSEGUIR EL AHORRO DE ENERGIA QUE RESULTA DEL USO DE LA DESCOMPRESION EXPLOSIVA, PERO EN EL QUE HAY BUENA CLARIDAD, ALTO RENDIMIENTO Y BUENA RESISTENCIA DE LAS FIBRAS. EL PROCEDIMIENTO DE ESTA INVENCION DEFINE CONDICIONES PARA CONSEGUIR ESTOS OBJETIVOS. ESTAS CONDICIONES INCLUYEN IMPREGNACION DE LOS PEDACITOS DE OTROS FRAGMENTOS DE MADERA BAJO CONDICIONES ESPECIFICAS Y COCIDO EN VAPOR SATURADO A ALTA TEMPERATURA Y PRESION, SEGUIDO POR DESCOMPRESION EXPLOSIVA, Y REFINADO. THIS INVENTION REFERS TO AN IMPROVED PROCEDURE FOR PREPARING PULP SUITABLE FOR MANUFACTURING PAPER. ALTHOUGH PROCEDURES USING EXPLOSIVE DECOMPRESSION HAVE BEEN KNOWN IN THE PAST, IT HAS BEEN BELIEVED THAT THESE HAVE TO BE CARRIED OUT AT RELATIVELY LOW TEMPERATURES. ALTHOUGH SUCH KNOWN EXPLOSIVE DECOMPRESSION PROCEDURES SAVED ENERGY, THE PHYSICAL RESISTANCE WAS LOW, THE COLOR WAS RELATIVELY DARK, AND THERE WAS A CONSIDERABLE LOSS OF PERFORMANCE. THIS INVENTION PROVIDES A PROCEDURE TO ACHIEVE THE ENERGY SAVINGS RESULTING FROM THE USE OF EXPLOSIVE DECOMPRESSION, BUT IN WHICH THERE IS GOOD CLARITY, HIGH PERFORMANCE AND GOOD STRENGTH OF THE FIBERS. THE PROCEDURE OF THIS INVENTION DEFINES CONDITIONS TO ACHIEVE THESE OBJECTIVES. THESE CONDITIONS INCLUDE IMPREGNATION OF THE PIECES OF OTHER WOOD FRAGMENTS UNDER SPECIFIC CONDITIONS AND COOKING IN SATURATED STEAM AT HIGH TEMPERATURE AND PRESSURE, FOLLOWED BY EXPLOSIVE DECOMPRESSION, AND REFINING.

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29-07-2010 дата публикации

4-phenylamino-quinazolin-6-yl-amides

Номер: US20100190977A1
Принадлежит: PFIZER INC

This invention provides quinazoline compounds of the formula: wherein: R 1 is halo; R 2 is H or halo; R 3 is a) C 1 -C 3 alkyl, optionally substituted by halo; or b) —(CH 2 ) n -morpholino, —(CH 2 ) n -piperidine, —(CH 2 ) n -piperazine, —(CH 2 ) n -piperazine-N(C 1 -C 3 alkyl), —(CH 2 ) n -pyrrolidine, or —(CH 2 ) n -imidazole; n is 1 to 4; R 4 is —(CH 2 ) m -Het; Het is morpholine, piperidine, piperazine, piperazine-N(C 1 -C 3 alkyl), imidazole, pyrrolidine, azepane, 3,4-dihydro-2H-pyridine, or 3,6-dihydro-2H-pyridine, each optionally substituted by alkyl, halo, OH, NH 2 , NH(C 1 -C 3 alkyl) or N(C 1 -C 3 alkyl) 2 ; m is 1-3; and X is O, S or NH; or a pharmaceutically acceptable salt thereof, as well as processes and intermediate compounds for making them, useful pharmaceutical compositions and methods of using the compounds in the treatment of proliferative diseases.

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09-06-1982 дата публикации

Cleaning cloth

Номер: EP0053201A1
Принадлежит: CARL FREUDENBERG KG

1. A cleaning cloth for household and industrial use consisting of a soft resilient needled nonwoven fabric (3) having an imprint of rubber strips (1) surmounting the top of the needled nonwoven fabric relief-like, characterised in that the height of the rubber strips (1) is about 0.2 to 0.4 times their width but not more than about 0.5 times the thickness of the nonwoven fabric (3), that the nonwoven fabric is carrying on its underside a continuous layer (2) of an open-pore latex foam which projects above the surface opposing the top surface of the needled nonwoven fabric to the extent of about 10 to 40 percent of the thickness of the nonwoven fabric.

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13-08-2009 дата публикации

Contactless detection cell with reduced detection channel cross-section

Номер: US20090201035A1
Принадлежит: AGILENT TECHNOLOGIES INC

A contactless detection cell ( 1 ) for detecting an electrical property of one or more sample compounds in a flow path is described. The contactless detection cell ( 1 ) comprises a transmitter electrode ( 3 ) adapted for capacitively coupling an AC current into a detection channel ( 4 ) of the flow path, and a receiver electrode ( 5 ) adapted for receiving the AC current that has been coupled into the detection channel ( 4 ). An inner cross-section (ID DET ) in at least a section of the detection channel is different than an inner cross-section (ID SEP ) of the flow path ( 2 ) towards the detection channel ( 4 ).

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18-12-1991 дата публикации

Roboting drug dispensing system.

Номер: EP0461161A1

La présente invention se rapporte à un système de robot automatisé servant à la distribution de médicaments depuis des fioles (8) jusque dans des récipients (4) contenant un liquide, tels que des sacs IV ou des seringues. Dans ledit système, un robot (20) sélectionne une fiole (8) et un récipient approprié (4) et transporte ceux-ci vers une station de traitement (60), conjointement avec une aiguille (53) qui peut être à double extrémité. A la station de traitement (60), le contenu de la fiole (8) est transféré dans le récipient (4). Une partie du contenu du récipient (4) peut être transférée dans la fiole (8), pour permettre de reconstituer le contenu de la fiole et/ou de rincer la fiole de son contenu, et un organe agitateur peut être prévu pour la fiole (8). Divers dispositifs supplémentaires peuvent être prévus, tels qu'un dispositif de décapsulage (34) pour les fioles (8), une station de nettoyage par tampons d'alcool (90) servant au nettoyage du sommet d'une fiole (8) et/ou de l'orifice d'entrée d'un sac IV (4) ou d'une seringue. Une imprimante d'étiquettes (75) peut en outre être prévue, de sorte que le robot (20) peut acheminer une étiquette avec le sac IV finalement traité (4) et la fiole vide (8) jusqu'à une station de vérification. Lors de l'utilisation de sacs, la présente invention se caractérise par un transporteur transportant des plateaux (42) de sacs (4) vers une station de préhension pour le robot (20). Les plateaux (42) confèrent plus de rigidité aux sacs (4), permettant ainsi leur manipulation par le robot (20). En vue de présenter les aiguilles (53) au robot (20) pour leur préhension, on peut utiliser des plateaux d'aiguilles (51), dans lesquels les aiguilles (53) sont disposées parallèlement les unes aux autres dans une position de préhension. Le robot (20) peut comporter des doigts préhenseurs (200) présentant une surface préhensile (202) conçue pour saisir une fiole (8) et une autre surface pré ...

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27-10-2011 дата публикации

Removing chlathrate inhibitors from contaminated petroleum streams

Номер: US20110259794A1
Принадлежит: Chevron USA Inc

A process is presented for treating crude oil that contains a clathrate hydrate inhibitor. In the process, a crude oil contaminated with the inhibitor is maintained in a vessel at inhibitor removal conditions to produce a treated crude oil having a reduced methanol concentration.

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05-03-2007 дата публикации

Continuous, mobile spiked mat with higher lift

Номер: CZ17319U1
Автор: Adámek@Bohuslav
Принадлежит: Adámek@Bohuslav

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12-02-1927 дата публикации

Process for producing dinas refractory material using lime emulsion

Номер: FR617049A
Автор: Bohuslav Brabec
Принадлежит:

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08-04-2003 дата публикации

1-heterocycle substituted diarylamines

Номер: US6545030B1
Принадлежит: Warner Lambert Co LLC

1-Heterocycle substituted diarylamines, methods of making and using them, and compositions containing them.

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11-10-1960 дата публикации

Device for automatic periodic gauging of viscosity

Номер: US2955459A
Принадлежит: Individual

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12-02-2004 дата публикации

Method of continuous casting and machine for implementation of this method

Номер: WO2004012882A1
Принадлежит: TRINECKÉ ZELEZÁRNY a.s.

The method of continuous casting of metals, especially steel, wherein the melted metal is continuously poured to the inlet of the mold, where it gradually cools down and from where solidified semi-product moves to further processing through its outlet, whilst the auxiliary coolant in the form of at least one wire, band, or bar from material similar to the continuously cast material is loaded to the mold inlet. The loaded auxiliary coolant is disposed by electromagnet with the forced harmonic oscillation, wherein amplitude, frequency, and wavelength vary in relation to physical-chemical parameters of continuously cast metal and technological conditions of casting process.

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20-07-2000 дата публикации

4-arylamino, 4-aryloxy, and 4-arylthio diarylamines and derivatives thereof as selective mek inhibitors

Номер: CA2348236A1
Принадлежит: Individual

The invention provides compounds of formula (II), wherein Ar, R3, R4, R5, R6, R7, R8 and W have the meanings given in the description. They are selective MEK inhibitors.

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31-07-1997 дата публикации

Biodegradable ester quats as flotation aids

Номер: DE19602856A1
Принадлежит: Henkel AG and Co KGaA

The invention concerns the use of so-called quaternary esters as an aid for flotation of non-sulfidic minerals. It was discovered that the products of quaternary esterification of mono, di or trialkanolamine containing aliphatic carboxylic acids present good collector properties on the one hand, especially for the flotation of silicates, and on the other hand an exceptional biodegradability under both aerobic as well as anaerobic conditions.

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09-08-2010 дата публикации

Lock system hydraulic device with parallel connected hydraulic cylinders in rail-switches

Номер: CZ21157U1
Принадлежит: DT-VÝHYBKÁRNA A STROJÍRNA, a.s.

The hydraulic equipment of the locking device with hydraulic cylinders in parallel connection designed for the railway turnout switch rails setting, consists of main reverse pump (1) situated on the mutual shaft (0) is the auxiliary reverse pump (2), which is connected with hydraulic circuit (17) of the main reverse pump (1) via couple of one-way valves (8) for discharge and the couple of one-way valves (9) for suction via throttling element (6) with hydraulic liquid tank (5) on which the main reverse pump (1) and the auxiliary reverse pump (2) are connected via one-way suction valves (4).

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01-12-1998 дата публикации

DERIVATIVES OF 2- (4-BROMINE OR 4-PHENYLAMINE IODINE) BENZOIC ACID

Номер: UY25075A1
Принадлежит: Warner Lambert Co

La presente invención se refiere a los derivados de ácido benzoico fenilamino, benzamidas y alcohol bencílico de la fórmula (I), donde: R1 es H, hidroxi, alquilo, alcoxi, halo, trifluorometil o CN; R2 es H; R3, R4 y R5 son independientemente H, hidroxi, halo, trifluorometil, alquilo, alcoxi, nitro, CN; Z es COOH, tetrazolil, CONH2, CONHNH2 o CH2OH; y las sales farmacéuticamente aceptables de los mismos. Asimismo, la invención se refiere a un procedimiento para su preparación, a composiciones farmacéuticas que los contienen y a su uso en terapia. Dichos compuestos son inhibidores de MEK y, como tales, son eficaces para el tratamiento del cáncer y otras enfermedades proliferativas. Ej. no limitante: 2-(4-Bromo-2-metil-fenilamino)-4-fluoro-ácido benzoico.

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30-10-2001 дата публикации

Benzo heterocycles and their use as demek inhibitors

Номер: BR9916904A
Принадлежит: Warner Lambert Co

Patente de Invenção: "BENZO HETEROCICLOS E SEU USOCOMO INIBIDORES DE MEK". A invenção provê compostostendo fórmula (1) onde W é OH, ou derivados do ácido carboxílico,e Q é um resíduo orto fenileno condensado - heterociclo. Estescompostos são úteis como inibidores MEK, particularmente notratamento de doenças proliferativas tais como câncer.

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14-06-1985 дата публикации

MECHANISM FOR GEARBOXES

Номер: FR2556292A1
Принадлежит: Ustav Pro Vyzkum Motorovych Vozidel

L'INVENTION EST RELATIVE A UNE COMMANDE DE BOITES DE VITESSES COMPORTANT UNE MARCHE ARRIERE ET UN AUTRE SUPPORT COMMANDES PAR UNE BARRE DE CHANGEMENT COMMUNE MOBILE SEULEMENT DANS LE SENS DE SON AXE. LA BARRE DE CHANGEMENT 2 PORTE DEUX BOSSAGES RADIAUX 4, 5. UN LEVIER BASCULANT MONTE SUR UN AXE 7 COMPORTE UN PREMIER BRAS 8 COMMANDANT LA ROUE INTERPOSEE DE MARCHE ARRIERE 11 ET UN SECOND BRAS QUI, POUR LE POINT MORT ET L'ENGAGEMENT DE L'AUTRE RAPPORT, S'APPUIE DANS LE SENS PERIPHERIQUE SUR LE BOSSAGE 5 ALORS QUE, LORSQU'ON VIENT ENGAGER LA MARCHE ARRIERE, IL PENETRE ENTRE LES DEUX BOSSAGES 4, 5, CE QUI COMMANDE LE BASCULEMENT DU LEVIER 7. THE INVENTION RELATES TO A CONTROL FOR GEARBOXES INCLUDING A REVERSE GEAR AND ANOTHER SUPPORT CONTROLLED BY A MOBILE COMMON CHANGE BAR ONLY IN THE DIRECTION OF ITS AXIS. THE CHANGE BAR 2 CARRIES TWO RADIAL BOSSES 4, 5. A TILTING LEVER MOUNTED ON AN AXLE 7 INCLUDES A FIRST ARM 8 CONTROLLING THE INTERPOSED REVERSE WHEEL 11 AND A SECOND ARM WHICH, FOR THE NEUTRAL POINT AND THE ENGAGEMENT OF L 'OTHER GEAR, IS BASED IN THE PERIPHERAL SENSE ON BOSS 5 WHILE, WHEN YOU COME TO ENGAGE REVERSE, IT PENETS BETWEEN THE TWO BOSSES 4, 5, WHICH CONTROLS THE TILTING OF LEVER 7.

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29-11-1929 дата публикации

Thermal installation for vehicles, flying machines, boats and other marine craft

Номер: FR670497A
Автор: Bohuslav Stoces
Принадлежит:

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09-07-1970 дата публикации

Process for the production of globoid gears

Номер: DE1963693A1
Принадлежит: Skoda np

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23-08-2002 дата публикации

OXYGEN ESTERS OF 4-IODINE PHENYLAMINE BENZHYDROXAMIC ACIDS AS MEK INHIBITORS

Номер: PE20020664A1
Принадлежит: Warner Lambert Co

SE REFIERE A ESTERES OXIGENADOS DE ACIDOS 4-YODO FENILAMINO BENZHIDROXAMICOS DE FORMULA I DONDE R1 ES H, HALOGENO, NITRO; R2 Y R3 SON H, F; R4 ES H, Br, I, Cl, F; R5 ES H, HALOGENO, OH, ALQUILO C1-C8, ALCOXI C1-C8, TRIFLUOROMETILO, CIANO; n ES 1-5; R6, R7, R8, R9 Y R10 SON H, ALQUILO C1-C8, CICLOALQUILO C3-C8, HIDROXI, ALCOXI C1-C8, ENTRE OTROS; W ES O, NRa; R11 ES H, ALQUILO C1-C8, ALQUENILO C2-C6, CICLOALQUILO C3-C8, ENTRE OTROS. ADEMAS SE REFIERE AL USO EN COMBINACION CON UN AGENTE QUIMIOTERAPICO COMO PACLITAXEL, DOCETAXEL, VINCRISTINA, VINBLASTINA, VINORELBINA, VINFLUNINA; TAMBIEN SE REFIERE A LAS FORMAS CRISTALINAS I Y II DE N-(2,3-DIHIDROXI-PROPOXI)-3,4-DIFLUORO-2-(2-FLUORO-4-YODO-FENILAMINO)-BENZAMIDA QUE SE CARATERIZA POR SU PATRON DE DIFRACCION DE RAYOS X. SON COMPUESTOS PREFERIDOS 3,4 DIFLUORO-2-(2-FLUORO-4-YODO-FENILAMINO)-N-(2-HIDROXI-ETOXI)-BENZAMIDA, 5-CLORO-2-(2-CLORO-4-YODO-FENILAMINO)-N-(2,3-DIHIDROXI-PROPOXI)-3,4-DIFLUORO-BENZAMIDA, ENTRE OTROS. LOS COMPUESTOS INHIBEN A LAS ENZIMAS QUINASAS MAPK/ERK (MEK) Y PUEDEN SER UTILES PARA EL TRATAMIENTO DEL CANCER, RESTENOSIS, PSORIASIS, ATEROSCLEROSIS REFERS TO OXYGEN ESTERS OF 4-IODINE PHENYLAMINE BENZHYDROXAMIC ACIDS OF FORMULA I WHERE R1 IS H, HALOGEN, NITRO; R2 AND R3 ARE H, F; R4 IS H, Br, I, Cl, F; R5 IS H, HALOGEN, OH, C1-C8 ALKYL, C1-C8 ALCOXY, TRIFLUOROMETHYL, CYANE; n IS 1-5; R6, R7, R8, R9 AND R10 ARE H, C1-C8 ALKYL, C3-C8 CYCLOALKYL, HYDROXY, C1-C8 ALCOXY, AMONG OTHERS; W ES O, NRa; R11 IS H, C1-C8 ALKYL, C2-C6 ALKENYL, C3-C8 CYCLOALKYL, AMONG OTHERS. ALSO REFERS TO THE USE IN COMBINATION WITH A CHEMOTHERAPY AGENT SUCH AS PACLITAXEL, DOCETAXEL, VINCRISTINE, VINBLASTIN, VINORELBIN, VINFLUNIN; IT ALSO REFERS TO THE CRYSTALLINE FORMS I AND II OF N- (2,3-DIHYDROXY-PROPOXI) -3,4-DIFLUORO-2- (2-FLUORO-4-IODO-PHENYLAMINE) -BENZAMIDE THAT IS CHARACTERIZED BY ITS PATTERN OF X-RAY DIFFRACTION. THE PREFERRED COMPOUNDS ARE 3,4 DIFLUORO-2- (2-FLUORO-4-IODO-PHENYLAMINE) -N- (2-HYDROXY-ETOXY) -BENZAMIDE, 5- ...

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05-02-1985 дата публикации

Process for simultaneous and continuous consolidation and coating of a non-woven textile

Номер: CA1182068A
Принадлежит: CARL FREUDENBERG KG

ABSTRACT A process for producing a non-woven textile containing a bonding agent, and an adhesive on one side of the textile; in which the radiation polymerizable bonding agent is printed onto the textile from one side while the adhesive is printed on in the form of a powder by a powder-point or screen printing process from the other side. The printed textile is then subjected to irradiation from a mercury vapour lamp of which about 10 to 30% of the radiation is in the ultra-violet region for polymerizing the bonding agent. The remainder radiation serves to heat the material so that the particles of adhesive coalesce sufficiently to maintain their geometric shape distribution in the material. The material is subsequently dried, finished and the adhesive sintered. Using the screen printing process at least 95% of the particles in the powder are less than 0.1 mm in diameter, and using the powder-point process, 95% of the particles are less than 0.2 mm diameter.

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12-06-1913 дата публикации

Improvements in and relating to the Production of Dot, Grained, or the like Screens.

Номер: GB191225899A
Принадлежит: Individual

25,899. Hervert, A., Hervert, B., and Jahn, O. Dec. 31, 1911, [Convention date]. Photo-mechanical printing-surfaces; contact printing - frames, with pneumatic pressure devices.-For half-tone process work, a screen of thin glass is used and the grain is produced by spraying fine dots of varnish or Indian ink with an air brush. In order to enhance the solid effect, the finished picture may be similarly sprayed. The Specification as open to inspection under Section 91 (3) (a) describes also an alternative method for making the screen, and a printing- frame. This method consists in spraying a plate and subsequently etching it. A screen thus produced is used for large size reproductions by enlarging a half-tone diapositive on to negative paper. In the printing - frame the sensitive stone 16 is housed on blocks 19, 20 and between blocks 17, 18. The lid comprises a frame 8 and two rings of rubber packing 5, 7, between which is a thin celluloid plate 6. The lid is clamped down on the packing-rim 4 of the frame 1 by the compound lever 10, 13 and catch 15. The celluloid sheet 6 presses the negative on to the stone 16, and the printing pressure is increased by exhausting air from the frame by the air-pump 23. The frame can be tilted on the supporting - pivot 2. This subject-matter does not appear in the Specification as accepted.

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04-03-1935 дата публикации

Improvements to control devices for motor vehicles

Номер: FR44555E
Автор: Bohuslav Kacer, Max Nohel
Принадлежит:

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03-02-1991 дата публикации

4-(n-substituted amino)-2-butynyl-1-carbamates and thiocarbamates and derivatives thereof as centrally acting muscarinic agents

Номер: CA2022511A1
Принадлежит: Warner Lambert Co LLC

ABSTRACT 4-(N-Substituted amino)-2-butynyl-1-carbamates and thiocarbamates and derivatives thereof are described, as well as methods for the preparation and pharmaceutical compositions of same, which are useful as centrally acting muscarinic agents and are useful as analgesic agents for the treatment of pain, as sleep aids and as agents for treating the symptoms of senile dementia, Alzheimer's disease, Huntington's chorea, tardive dyskinesia, hyperkinesia, mania, or similar conditions of cerebral insufficiency characterized by decreased cerebral acetylcholine production or release.

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03-05-1995 дата публикации

Improved organic vehicle and electronic paste.

Номер: EP0619161A3
Автор: Berhan Tecle
Принадлежит: EI Du Pont de Nemours and Co

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08-11-1983 дата публикации

Method of simultaneous, continuous printing of a porous and flexible flat material

Номер: CA1156521A
Принадлежит: CARL FREUDENBERG KG

METHOD AND APPARATUS FOR SIMULTANEOUS, EVEN, CONTINUOUS PRINTING OF A POROUS AND FLEXIBLE FLAT MATERIAL ABSTRACT An improved method for the simultaneous, even, contin-uous printing of flexible, flat material wherein separate pastes are applied to top and bottom surfaces of the material and then dried, the improvement comprising applying the separate pastes to each surface of the flat material and to zones on each surface that are directly opposite each other. In another aspect the invention provides an apparatus for the simultaneous, even, continuous printing of flexible, flat material wherein separate pastes are applied to top and bottom surfaces of the material which comprises two pressure cylinders revolving in opposite directions at equal peripheral speeds, said cylinders arranged parallel to each other with an adjustable interaxial distance therebetween, and at least one cylinder has a soft elastic surface. The invention results in substantially reduced costs for the apparatus and hence production costs.

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29-08-1992 дата публикации

Steam explosion pulping process for papermaking

Номер: CA2037275A1
Автор: Bohuslav V. Kokta
Принадлежит: Bohuslav V. Kokta

ABSTRACT This invention relates to an improved process preparing pulp suitable for papermaking, resulting in lower cost, higher yield and brightness consisting of short time saturated steam cooking of chips impregnated with alkaline solutions of sulphites and carbonates, chlorides, sulfates or bicarbonates in the temperature range of 180 to 210°C followed by explosive decompression and fiber refining.

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22-06-1979 дата публикации

NON-WOVEN WITH THE APPEARANCE OF FABRIC, USABLE IN PARTICULAR AS A LINING

Номер: FR2410068A1
Принадлежит: CARL FREUDENBERG KG

UN NON-TISSE SELON L'INVENTION EST DE CONSTITUTION HOMOGENE ET PRESENTE A L'ENDROIT UN MOTIF GAUFRE REGULIER FORME D'AIRES SEPAREES D'UN DIAMETRE MAXIMAL DE 0,45MM ET D'UN ESPACEMENT MUTUEL DE TOUT AU PLUS 1MM, AUQUEL EST SUPERPOSE UN MOTIF DE LIANT IMPRIME REGULIER QUI EST FORME D'AIRES SEPAREES D'UN DIAMETRE MAXIMAL DE 0,45MM ET D'UN ESPACEMENT MUTUEL DE TOUT AU PLUS 0,7MM. L'ENVERS DU NON-TISSE PEUT PORTER UN MOTIF D'ADHESIF POUR SA FIXATION DANS UN VETEMENT, MAIS LE NON-TISSE PEUT EGALEMENT ETRE COUSU. A NON-WOVEN ACCORDING TO THE INVENTION IS OF HOMOGENEOUS CONSTITUTION AND PRESENTS AT THE LOCATION A REGULAR WAFFLE PATTERN IN THE FORM OF SEPARATE AREAS WITH A MAXIMUM DIAMETER OF 0.45MM AND WITH A MUTUAL SPACING OF AT LEAST 1MM, WHICH IS SUPERIMPOSES A PATTERN OF REGULAR PRINTED BINDER WHICH IS IN THE FORM OF SEPARATE AREAS WITH A MAXIMUM DIAMETER OF 0.45MM AND A MUTUAL SPACING OF NO MORE THAN 0.7MM. THE BACK OF THE NON-WOVEN MAY BE A PATTERN OF ADHESIVE FOR ITS FIXING IN A CLOTHING, BUT THE NON-WOVEN MAY ALSO BE STITCHED.

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03-06-2009 дата публикации

Phase modulation digital generator

Номер: CZ300501B6
Принадлежит: Západoceská univerzita v Plzni

In the present invention, there is disclosed a device comprising four transistors connected via drive circuits with generator outputs (a, b, c, d). On the input of the generator, there are set requested frequencies (F) with number of bits N1+1 and a phase (P) with number of bits N2+1 wherein the generator is connected to a clock signal (Clk). The frequency (F), complemented from above with zeros to N3+1 length, is connected to an input (B) of a first adder (1), which adds a value at an input (A) to the value at the input (B). The input (A) of the first adder (1) is connected with an output (Q) of a phase register (3), which has N3+1 bits. An output (Z) of the first adder (1), which has N3+1 bits is connected to an input (D) of the phase register (3) and the most significant bits of the output (Z) of the first adder (1) of N2+1 length are connected to the input (A) of a second adder (2), which subtracts the value at the input (B) from the value at the input (A) and the input (B) of the second adder (2) is connected to the phase (P). The most significant bit at the second adder (2) output (S) is connected to the input (D) of a register (4). The most significant bit of the register (3) output (Q) is connected via a delay line (5) to the first input of a first logic gate (7) and to the first input of a second logic gate (8). The most significant bit of the register (3) output (Q) is connected to the second input of the first logic gate (7) and to the second input of the second logic gate (8). Output (Q) of the register (4) is connected via a delay line (6) to the first input of a third logic gate (9) and to the first input of a fourth logic gate (10) and the register (4) output (Q) is also connected to the second input of the third logic gate (9) and to the second input of the fourth logic gate (10). The first logic gate (7) has an output (a), which serves for controlling the upper transistor in the left half bridge and the second logic gate (8) has an output (b), which ...

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11-03-1992 дата публикации

Modified process for preparing pulp for paper making

Номер: CA2024935A1
Автор: Bohuslav V. Kokta
Принадлежит: Bohuslav V. Kokta

ABSTRACT This invention relates to an improved process preparing pulp suitable for papermaking, consisting of short time saturated steam cooking of chips impregnated with alkaline solutions of sulphites in the temperature range of 180 to 210°C, instantaneous pressurizing the reactor with cool nitrogen after cooking to super atmospheric pressure from 25 to 50 atm followed by explosive decompression and fiber refining.

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01-08-1992 дата публикации

Process for the production of polystyrene composites reinforced with hybrid glass/cellulose fibers

Номер: CA2035328A1
Принадлежит: Bohuslav V. Kokta, Debesh C. Maldas

ABSTRACT Hybrid composites were prepared from silane coated glass/cellulose fibers and polystyrene. The cellulose fibers were surface coated with polymer + isocyanate, silane, and grafted with a polymer. Treated cellulose/glass fiber-filled composites show excellent mechanical properties in addition to resistance even under adverse conditions, e.g. exposure to boiling water for 24 hours and to heat at +105°C for 5 days as well as at a subzero temperatures (e.g. -20°C).

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17-10-2001 дата публикации

Sulphohydroxamic acids and sulphohydroxamates and their use as mek inhibitors

Номер: EP1144372A1
Автор: Haile Tecle
Принадлежит: Warner Lambert Co LLC

Sulfohydroxamic acid diarylamines of formula (I), in which the variables are as defined in the claims, are inhibitors of MEK and are effective in the treatment of proliferative diseases, cancer, stroke, heart failure, xenograft rejection, arthritis, cystic fibrosis, hepatomegaly, cardiomegaly, Alzheimer's disease, complications of diabetes, septic shock, and viral infection.

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30-06-1982 дата публикации

Process for simultaneously and continuously strengthening and coating a fleece fabric

Номер: EP0054628A1
Принадлежит: CARL FREUDENBERG KG

1. A process for continuously consolidating a nonwoven and simultaneously coating it with a binder and with an adhesive composition, in which process the binder is synchronously counter-printed from one side against the adhesive composition, printed on from the other side, in the form of matching part-surfaces, the part-surfaces being spaced apart from one another, characterised in that a binder crosslinkable by ultraviolet radiation is printed onto the nonwoven from the underside by means of a relief-printing, planographic printing or gravure-printing cylinder having a soft, resilient rubber covering, that a thermoplastic adhesive composition ist printed onto the nonwoven from the upper face by the powder dot or screen printing process and that subsequently the nonwoven is irradiated with light which contains 10 to 30% of its total energy in the form of ultraviolet radiation, the total power being so chosen that the binder becomes crosslinked and the geometrical distribution of the adhesive composition becomes intrinsically stabilised, after which the nonwoven receives a final treatment by drying and/or sintering of the adhesive composition.

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20-07-2000 дата публикации

Benzenesulfonamide derivatives and their use as mek inhibitors

Номер: CA2349832A1
Принадлежит: Individual

Benzenesulfonamides of formula (I), in which W is OR1, NR2OR1, NRARB, NR2NRARB, or NR2(CH2)2-4NRARB and the other variables as de fined in the claims, are inhibitors of MEK and are effective in the treatment of proliferative diseases, cancer, stroke, heart failure, xenograft rejection, arthritis, cystic fibrosis, hepatomegaly, cardiomegaly, Alzheimer's disease, complications of diabetes, septic shock, and viral infection.

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