SYSTEM AND METHOD OF MODULAR CLONING

System for producing a nucleic acid construct of interest, said system comprising: a set of n entry DNAs numbered 1 to n, n being an integer of at least 2, each of said n entry DNAs comprising in this order: (i) a type IIs restriction endonuclease recognition site followed by the cleavage site thereof; (ii) a sequence portion linking the cleavage site of said recognition site of item (i) with the cleavage site of the recognition site of the following item (iii), and (iii) a cleavage site of a further type Ms restriction endonuclease recognition site followed by the recognition site of said cleavage site; the cleavage sites of the type IIs restriction endonuclease recognition sites of item (iii) of entry DNAs 1 to n−1 are complementary to the cleavage sites of the type IIs restriction endonuclease recognition sites of item (i) of entry DNAs 2 to n, respectively; the cleavage site of the type Ms restriction endonuclease recognition site of item (iii) of entry DNA n is complementary to the cleavage site of the type IIs restriction endonuclease recognition site of item (i) of entry DNA 1 for allowing annealing of complementary single-stranded overhangs formed by restriction at recognition site (i) of entry DNA 1 and at recognition site (iii) of entry DNA n; said system further comprising a destination vector comprising in this order: (I) a type Ms restriction endonuclease recognition site followed by the cleavage site thereof; (II) a vector backbone preferably comprising a selectable marker gene, said vector backbone linking the cleavage sites of said recognition sites of items (I) and the following item (III); (III) a further cleavage site of a type Ms restriction endonuclease recognition site followed by the recognition site of said cleavage site, and (IV) optionally, an insert between the recognition sites of item (III) and item (i); said cleavage sites of items (I) and (III) being different and non-complementary, said recognition sites of items (I) and (III) being ...

PRODUCE DRYER DISTRIBUTION SYSTEM

Embodiments for implementing a produce dryer system, method, and apparatus are provided. For example, a produce dryer system may include a pickup station comprising a bin configured to be contain produce that is designated for drying, a first dryer and a second dryer configured to receive the bin and dry the produce in the bin by running for a dryer cycle associated with the produce, and a transport device. The transport device may include a ground transport chassis configured to travel along a predetermined path, a driven arm attached to the ground transport chassis that is configured to pick up and set down the bin, and a controller configured to determine which of the first dryer and the second dryer to use for drying the produce in the bin and for positioning and removing the bin from the first dryer or second dryer with the transport device. 1. A produce dryer system , comprising:a pickup station comprising a bin configured to contain produce that is designated for drying;a first dryer and a second dryer configured to receive the bin and dry the produce in the bin by running for a dryer cycle associated with the produce; and a ground transport chassis configured to travel along a predetermined path;', 'a driven arm attached to the ground transport chassis that is configured to pick up and set down the bin; and', 'a controller configured to determine which of the first dryer or the second dryer to use for drying the produce in the bin and for positioning and removing the bin from the first dryer or second dryer with the transport device., 'a transport device comprising2. The produce dryer system of claim 1 ,wherein the pickup station comprises a designated area to receive the bin within a queue of other bins, each bin containing produce that is designated for drying.3. The produce dryer system of claim 1 ,a hopper configured to receive the produce from the bin,wherein the transport device is configured to deposit the produce into the hopper by driving the driven ...

HPPD VARIANTS AND METHODS OF USE

In the present invention, HPPD polypeptides and plants containing them showing a full tolerance against one or more HPPD inhibitor herbicides belonging to various chemical classes are described. A set of mutant HPPD polypeptides have been designed which have either no or only a significantly reduced affinity to HPPD inhibitor herbicides and, at the same time, the rate of dissociation of the HPPD inhibitors of the mutant HPPD polypeptide is increased to such an extent that the HPPD inhibitors no longer act as slow-binding or slow, tight-binding inhibitors but, instead of this, have become fully reversible inhibitors. In particular, isolated polynucleotides encoding mutant HPPD polypeptides conferring tolerance to HPPD inhibitor herbicides belonging to various chemical classes are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed. 1. A recombinant nucleic acid molecule encoding an enzymatically active 4-hydroxyphenylpyruvate dioxygenase (HPPD) polypeptide whose amino acid sequence (1) comprises the substitutions (a) an alanine at the amino acid position corresponding to amino acid position 268 of SEQ ID NO:1 , (b) a proline at the amino acid position corresponding to amino acid position 335 of SEQ ID NO:1 , (c) a histidine or an aspartic acid at the position corresponding to amino acid position 336 of SEQ ID NO:1 , and (d) a serine at the position corresponding to amino acid position 337 of SEQ ID NO:1; or i. a lysine or leucine at the amino acid position corresponding to amino acid position 213 of SEQ ID NO:1; and/or', 'ii. an alanine at the amino acid position corresponding to amino acid position 215 of SEQ ID NO:1; and/or', 'iii. an arginine, asparagine, leucine, glutamic acid, proline or serine at the amino acid position corresponding to amino acid position 270 of SEQ ID NO:1; and/or', 'iv. an arginine, lysine, glutamine, methionine or histidine at the amino acid position corresponding to amino acid position 315 of ...

ATRIAL NATRIURETIC PEPTIDE ENGRAFTED ANTIBODIES

The present invention relates to an antibody or a fragment thereof comprising at least one heterologous amino acid sequence incorporated within at least one CDR region of said antibody or fragment thereof, wherein said at least one heterologous amino acid sequence comprises an N-terminal linker sequence (Nils), an Atrial Natriuretic Peptide (ANP) and a C-terminal linker sequence (Ctls). Optionally, at least a portion of said at least one CDR region is replaced by said at least one heterologous amino acid sequence incorporated therein. The present invention further relates to such antibody or fragment thereof for use in a method for treatment, a composition comprising such antibody or fragment thereof, a nucleic acid or a mixture of nucleic acids encoding such antibody or fragment thereof, a host cell comprising such nucleic acid or such mixture of nucleic acids and to a process for producing such antibody or fragment thereof. 1: An antibody or a fragment thereof comprising at least one heterologous amino acid sequence incorporated within at least one CDR region of said antibody or fragment thereof , wherein said at least one heterologous amino acid sequence comprises an N-terminal linker sequence (Ntls) , an Atrial Natriuretic Peptide (ANP) and a C-terminal linker sequence (Ctls) , wherein optionally at least a portion of said at least one CDR region is replaced by said at least one heterologous amino acid sequence incorporated therein , and wherein i) amino acid residue HC res25 according to Kabat and the first amino acid residue of said ANP in case of an incorporation of said heterologous amino acid sequence within CDRH1;', 'ii) amino acid residue HC res51 according to Kabat and the first amino acid residue of said ANP in case of an incorporation of said heterologous amino acid sequence within CDRH2;', 'iii) amino acid residue HC res92 according to Kabat and the first amino acid residue of said ANP in case of an incorporation of said heterologous amino acid ...

ANTIBODY DRUG CONJUGATES OF KINESIN SPINDEL PROTEIN (KSP) INHIBITORS WITH ANTIB7H3-ANTIBODIES

The present application relates to novel binder drug conjugates (ADCs), to active metabolites of these ADCs, to processes for preparing these ADCs, to the use of these ADCs for the treatment and/or prophylaxis of diseases and to the use of these ADCs for preparing medicaments for treatment and/or prophylaxis of diseases, in particular hyperproliferative and/or angiogenic disorders such as, for example, cancer diseases. Such treatments can be effected as monotherapy or else in combination with other medicaments or further therapeutic measures. 2. Conjugate according to where A represents —C(═O)—.3. Conjugate according to where Rrepresents —H claim 1 , -L-#1 claim 1 , —COOH claim 1 ,{'sub': 2', '2', '1-3', '2', '2', '1-3', '2', '2', '2, '—C(═O)—NHNH, —(CH)NH, —C(═O)—NZ″(CH)NHor —C(═O)—NZ″CHCOOH, where Z″ represents —H or —NH.'}4. Conjugate according to where Rand Rrepresent —H or Rand Rtogether (with formation of a pyrrolidine ring) represent—{'sup': 11', '11, 'sub': 2', '2, 'CHR—CH— or —CH—CHR—;'}{'sup': '11', 'sub': 2', '2', '1-4, 'where Rrepresents —H, —COOH, —F, methyl, —CHF, -Omethyl, —CHOH, —C(═O)—O—(C-alkyl) or OH.'}5. Conjugate according to where Rrepresents -L-#1 or represents a phenyl group which may be mono- or polysubstituted by halogen claim 1 , C-alkyl or fluoro-C-alkyl claim 1 , or represents a C-alkyl group or fluoro-C-alkyl group which may optionally be substituted by —OY claim 1 , —SY claim 1 ,{'sup': 4', '4', '4', '4', '4', '4', '4', '4, 'sub': n', '2', '2, '—O—C(O)—Y, —O—C(═O)—NH—Y, —NH—C(═O)—Y, —NH—C(═O)—NH—Y, —S(O)—Y, —S(═O)—NH—Y, —NH—Yor —N(Y),'}wheren represents 0, 1 or 2,{'sup': '4', 'sub': 1-3', '1-3', '1-3, 'Yrepresents —H, phenyl which is optionally mono- or polysubstituted by halogen, Calkyl, or fluoro-C-alkyl, or represents alkyl which may be substituted by —OH, —COOH, and/or —NH—C(O)—C-alkyl.'}7. Conjugate according to where the substituent Rrepresents -L-#1.9. Conjugate according to where Rrepresents —H or —F.10. Conjugate according to ...

ANTIBODY DRUG CONJUGATES OF KINESIN SPINDEL PROTEIN (KSP) INHIBITORS WITH ANTI-B7H3-ANTIBODIES

The present application relates to novel binder drug conjugates (ADCs), to active metabolites of these ADCs, to processes for preparing these ADCs, to the use of these ADCs for the treatment and/or prophylaxis of diseases and to the use of these ADCs for preparing medicaments for treatment and/or prophylaxis of diseases, in particular hyperproliferative and/or angiogenic disorders such as, for example, cancer diseases. Such treatments can be effected as monotherapy or else in combination with other medicaments or further therapeutic measures. 2. Conjugate according to claim 1 , where A represents —C(═O)—.3. Conjugate according to claim 1 , where Rrepresents —H claim 1 , -L-#1 claim 1 , —COOH claim 1 , —C(═O)—NHNH claim 1 , —(CH)NH claim 1 , —C(═O)—NZ″(CH)NHor —C(═O)—NZ″CHCOOH claim 1 , where Z″ represents —H or —NH.4. Conjugate according to claim 1 ,{'sup': 2', '4, 'where Rand Rrepresent —H or'}{'sup': 2', '4', '11', '11, 'sub': 2', '2, 'claim-text': {'sup': '11', 'sub': 2', '2', '1-4, 'where Rrepresents —H, —COOH, F, methyl, —CHF, —Omethyl, —CHOH, —C(═O)—O—(C-alkyl) or OH.'}, 'where Rand Rtogether (with formation of a pyrrolidine ring) represent —CHR—CH— or —CH—CHR—;'}5. Conjugate according to claim 1 ,{'sup': 3', '4', '4', '4', '4', '4', '4', '4', '4', '4', '4, 'sub': 1-3', '1-3', '1-10', '1-10', 'n', '2', '2, 'claim-text': where', 'n represents 0, 1 or 2,', {'sup': '4', 'sub': 1-3', '1-3', '1-3, 'Yrepresents —H, phenyl which is optionally mono- or polysubstituted by halogen, C-alkyl or fluoro-C-alkyl, or represents alkyl which may be substituted by —OH, —COOH, and/or —NH—C(═O)—C-alkyl.'}], 'where Rrepresents -L-#1 or represents a phenyl group which may be mono- or polysubstituted by halogen, C-alkyl or fluoro-C-alkyl, or represents a C-alkyl group or fluoro-C-alkyl group which may optionally be substituted by —OY, —SY, —O—C(═O)—Y, —O—C(═O)—NH—Y, —NH—C(═O)—Y, —NH—C(═O)—NH—Y, —S(O)—Y, —S(═O)—NH—Y, —NH—Yor —N(Y),'}7. Conjugate according to where the substituent ...

HPPD VARIANTS AND METHODS OF USE

In the present invention, HPPD polypeptides and plants containing them showing a full tolerance against one or more HPPD inhibitor herbicides belonging to various chemical classes are described. 1. A recombinant nucleic acid molecule encoding a 4-hydroxyphenylpyruvate dioxygenase (HPPD) polypeptide consisting of an amino acid sequence comprising (a) a proline at the amino acid position corresponding to amino acid position 335 of SEQ ID NO:1 , (b) a histidine or an aspartic acid at the position corresponding to amino acid position 336 of SEQ ID NO:1 , and (c) a serine at the position corresponding to amino acid position 337 of SEQ ID NO:1 , and wherein said HPPD polypeptide is tolerant to one or more HPPD inhibitor herbicide(s).2. The recombinant nucleic acid molecule of claim 1 , wherein said encoded HPPD polypeptide consists of an amino acid sequence further comprisesi. a methionine, threonine, serine, or leucine at the amino acid position corresponding to amino acid position 204 of SEQ ID NO:1; and/orii. a lysine or leucine at the amino acid position corresponding to amino acid position 213 of SEQ ID NO:1; and/oriii. an arginine, lysine, glutamine, or leucine at the amino acid position corresponding to amino acid position 264 of SEQ ID NO:1; and/oriv. an arginine, glycine, or serine at the amino acid position corresponding to amino acid position 268 of SEQ ID NO:1; and/orv. an arginine, leucine, glutamic acid, proline or serine at the amino acid position corresponding to amino acid position 270 of SEQ ID NO:1; and/orvi. a serine, histidine, or lysine at the amino acid position corresponding to amino acid position 310 of SEQ ID NO:1; and/orvii. an arginine, methionine or histidine at the amino acid position corresponding to amino acid position 315 of SEQ ID NO:1; and/orviii. a histidine, alanine, phenylalanine, valine, or glycine at the amino acid position corresponding to amino acid position 330 of SEQ ID NO:1; and/orix. a proline, histidine, serine, isoleucine, ...

HPPD VARIANTS AND METHODS OF USE

In the present invention, HPPD polypeptides and plants containing them showing a full tolerance against one or more HPPD inhibitor herbicides belonging to various chemical classes are described. A set of mutant HPPD polypeptides have been designed which have either no or only a significantly reduced affinity to HPPD inhibitor herbicides and, at the same time, the rate of dissociation of the HPPD inhibitors of the mutant HPPD polypeptide is increased to such an extent that the HPPD inhibitors no longer act as slow-binding or slow, tight-binding inhibitors but, instead of this, have become fully reversible inhibitors. In particular, isolated polynucleotides encoding mutant HPPD polypeptides conferring tolerance to HPPD inhibitor herbicides belonging to various chemical classes are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed. 1. A recombinant nucleic acid molecule encoding an enzymatically active 4-hydroxyphenylpyruvate dioxygenase (HPPD) polypeptide whose amino acid sequence (I) comprises the substitutions (a) a glutamine or a lysine at the amino acid position corresponding to amino acid position 315 of SEQ ID NO: 1 , (b) a proline at the amino acid position corresponding to amino acid position 335 of SEQ ID NO: 1 , (c) a histidine or an aspartic acid at the position corresponding to amino acid position 336 of SEQ ID NO:1 , and (d) a serine at the position corresponding to amino acid position 337 of SEQ ID NO: 1; or i. a lysine or leucine at the amino acid position corresponding to amino acid position 213 of SEQ ID NO:1; and/or', 'ii. an alanine at the amino acid position corresponding to amino acid position 215 of SEQ ID NO:1; and/or', 'iii. an arginine, lysine, glutamine, or leucine at the amino acid position corresponding to amino acid position 264 of SEQ ID NO: 1; and/or', 'iv. an arginine, glycine, or serine at the amino acid position corresponding to amino acid position 268 of SEQ ID NO:1; and/or', 'v. an ...

REVERSAL AGENTS FOR NEUTRALIZING THE THERAPEUTIC ACTIVITY OF ANTI-FXIA ANTIBODIES

The present invention relates to reversal agents, which specifically bind to the anti-FXIa antibody 076D-M007-H04-CDRL3-N110D as described in WO2013/167669, and neutralize the therapeutic activity of this anti-FXIa antibody, as well as to compositions comprising these reversal agents. Methods of obtaining the antibodies or antigen-binding fragments thereof (such as Fab fragments) and nucleic acids encoding the same, are also provided. Furthermore, the invention relates to methods of use of these reversal agents, such as methods for neutralizing the therapeutic activity of the anti-FXIa antibody 076D-M007-H04-CDRL3-N110D, and to related methods as essential part of a general bleeding management. 1: A monoclonal antibody or antigen-binding fragment thereof that specifically binds to anti-FXIa antibody 076D-M007-H04-CDRL3-N110D and thereby inhibits the neutralizing activity of antibody 076D-M007-H04-CDRL3-N110D , wherein the antibody or antigen binding fragment thereof comprises HCDR1-3 and LCDR1-3 comprising the amino acid sequences of:a) SEQ ID NOs: 72, 73, 74, 76, 77, and 78, respectively;b) SEQ ID NOs: 86, 87, 88, 90, 91, and 92, respectively;c) SEQ ID NOs: 114, 115, 116, 118, 119, and 120, respectively;d) SEQ ID NOs: 128, 129, 130, 132, 133, and 134, respectively;e) SEQ ID NOs: 142, 143, 144, 146, 147, and 148, respectively;f) SEQ ID NOs: 156, 157, 158, 160, 161, and 162, respectively;g) SEQ ID NOs: 170, 171, 172, 174, 175, and 176, respectively; orh) SEQ ID NOs: 184, 185, 186, 188, 189, and 190, respectively.2: The monoclonal antibody or antigen-binding fragment according to claim 1 , wherein the antibody or antigen binding fragment thereof comprises a heavy chain sequence and a light chain sequence comprising the amino acid sequences of:a) SEQ ID NOs: 81 and 82, respectively;b) SEQ ID NOs: 95 and 96, respectively;c) SEQ ID NOs: 123 and 124, respectively;d) SEQ ID NOs: 137 and 138, respectively;e) SEQ ID NOs: 151 and 152, respectively;f) SEQ ID NOs: 165 and 166, ...

RADIO-PHARMACEUTICAL COMPLEXES

The invention provides a method for the formation of a tissue-targeting thorium complex, said method comprising; a) forming an octadentate chelator comprising four hydroxypyridinone (HOPO) moieties, substituted in the N-position with a methyl group, and a coupling moiety terminating in a carboxylic acid group; b) coupling said octadentate chelator to at least one tissue-targeting moiety targeting prolyl endopeptidase FAP; and c) contacting said tissue-targeting chelator with an aqueous solution comprising an ion of at least one alpha-emitting thorium isotope. A method of treatment of a neoplastic or hyperplastic disease comprising administration of such a tissue-targeting thorium complex, as well as the complex and corresponding pharmaceutical formulations are also provided. 2. The method of wherein step b) is conducted in aqueous solution.3. The method of claim 1 , wherein step b) further comprises activating the Rlinker moiety terminating in a carboxylic acid moiety with an amide-coupling reagent; and said amide-coupling reagent is a carbodiimide coupling reagent.4. The method of claim 1 , wherein step b) is conducted in aqueous solution at pH between 4 and 9.5. The method of claim 1 , wherein step b) is conducted between 15 and 50° C. for 5 to 120 minutes.6. The method of claim 1 , wherein step c) is conducted between 15 and 50° C. for 1 to 60 minutes.8. A tissue-targeting thorium complex formed or formable by the method of .9. A pharmaceutical formulation comprising at least one tissue-targeting thorium complex as defined in .10. The pharmaceutical formulation of further comprising citrate buffer.11. The pharmaceutical formulation of claim 9 , further comprising p-aminobutyric acid (PABA) claim 9 , and optionally EDTA and/or at least one polysorbate.12. A method of treatment of a hyperplastic or neoplastic disease in a human or non-human animal in need thereof claim 1 , comprising administration of at least one tissue-targeting thorium complex as defined in .13. ...

SYSTEM AND METHOD OF MODULAR CLONING

System for producing a nucleic acid construct of interest, said system comprising: 124-. (canceled)25. System for producing a nucleic acid construct of interest , said system comprising:a set of n entry DNAs numbered 1 to n, n being an integer of at least 2, preferably at least 3,each of said n entry DNAs comprising in this order:(i) a type IIs restriction endonuclease recognition site followed by the cleavage site thereof;(ii) a sequence portion linking the cleavage site of said recognition site of item (i) with the cleavage site of the recognition site of the following item (iii), and(iii) a cleavage site of a further type IIs restriction endonuclease recognition site followed by the recognition site of said cleavage site;the cleavage sites of the type IIs restriction endonuclease recognition site(s) of item (iii) of entry DNA(s) 1 to n−1 is/are complementary to the cleavage site(s) of the type IIs restriction endonuclease recognition site(s) of item (i) of entry DNA(s) 2 to n, respectively;the cleavage site of the type IIs restriction endonuclease recognition site of item (iii) of entry DNA n is complementary to the cleavage site of the type IIs restriction endonuclease recognition site of item (i) of entry DNA 1;said system further comprising a destination vector comprising in this order:(I) a type IIs restriction endonuclease recognition site followed by the cleavage site thereof;(II) a vector backbone comprising a selectable marker gene, said vector backbone linking the cleavage sites of said recognition sites of items (I) and the following item (III);(III) a further cleavage site of a type IIs restriction endonuclease recognition site followed by the recognition site of said cleavage site, and(IV) optionally, an insert between the recognition sites of item (III) and item (I);said system further comprising a nucleic acid linker comprising in the following order:(a) a type IIs restriction endonuclease recognition site;(b) a cleavage site of said recognition ...

Hochuntersetzendes getriebe

Die vorliegende Erfindung betrifft ein Getriebe mit einem Hohlrad, in dem ein flexibles Zahnrad angeordnet ist, wobei das flexible Zahnrad mit einem Wavegenerator in Verbindung steht und der Wavegenerator das flexible Zahnrad verformt, so dass es bereichsweise mit dem Hohlrad in Eingriff steht und wobei das flexible Zahnrad mindestens zwei Zahnsegmente umfasst, die mittels Federsegmenten miteinander verbunden sind und mindestens eines der Zahnsegmente eine Ausnehmung aufweist, in welcher ein Zapfenelement angeordnet ist. Aufgabe der vorliegenden Erfindung ist es, ein Getriebe bereitzustellen, das insbesondere auch bei kleineren Getriebedurchmessern eine ausreichende elastische Verformung des flexiblen Zahnrads ermöglicht und eine sehr kurze Gesamtlänge und dennoch eine hohe Torsionssteifigkeit aufweist. Hierzu ist erfindungsgemäß vorgesehen, dass jedes der Federsegmente eine Mittelebene aufweist, die eine zentrale Mittelachse des Getriebes beinhaltet und das jeweilige Federsegment in zwei Bereiche gleicher Länge unterteilt und jede Ausnehmung eine Mittelebene aufweist, die die zentrale Mittelachse des Getriebes beinhaltet und die Ausnehmung in zwei gleich große Bereiche unterteilt und die Mittelebene jedes Federsegments einen unterschiedlichen Abstand zu der auf jeder Seite der Mittelebene des Federsegments daneben liegenden Mittelebene der Ausnehmung aufweist.

Vorrichtung zur Fixation von Knochenfrakturen

Vorrichtung (10) zur Fixation von Knochenfrakturen, insbesondere im proximalen Bereich eines Humerus, mit einem im Markkanal des gebrochenen Knochens bzw. intramedullär plazierbaren Nagel, Schaft o. dgl. Implantat (11, 18) und einer mittels Schrauben (12) o. dgl. am Implantat (11, 18) fixierbaren Platte (14), wobei die Platte (14) Bohrungen (15) zur Aufnahme, insbesondere winkelstabilen Aufnahme, von Knochenschrauben (16) aufweist. Die Platte (14) ist in vorbestimmter Lage relativ zum Implantat (11, 18), ggf. auch im Abstand zum Knochen, winkel- und abstandsstabil fixierbar.

Process for the catalytic reduction of alkyne compounds

trolley

Fahrwagen (1), insbesondere zur Inspektion von Abwasserkanälen und zur Kontrolle und Reinigung von Klimakanälen, mit einem Wagenkern (2) und mindestens vier Rädern (3a bis 3f), wobei an dem Wagenkern ein Kameraarm (7) und/oder ein Arbeitsarm (10) befestigbar sind, dadurch gekennzeichnet, dass der Wagenkern (2) zwei miteinander verbundene Längsteile (21, 22) aufweist, die eine Öffnung (23') umschließen und die an ihrer der Öffnung (23') zugewandten Seite mindestens über einen Teil ihrer Länge mindestens zwei parallel zueinander verlaufende Nuten in Form eines oberen Nutenpaares (24, 25) und eines unteren Nutenpaares (26, 27) aufweisen. Carriage (1), in particular for inspecting sewer channels and for checking and cleaning air conditioning ducts, with a carriage core (2) and at least four wheels (3a to 3f), a camera arm (7) and / or a working arm (10 ) can be fastened, characterized in that the carriage core (2) has two interconnected longitudinal parts (21, 22) which enclose an opening (23 ') and which on their side facing the opening (23') at least over part of their length have at least two mutually parallel grooves in the form of an upper pair of grooves (24, 25) and a lower pair of grooves (26, 27).

Hydraulic quick-slack-take-up pulsator for disk brakes

Breaking device for breaking cocoa beans

Rubber regeneration process

Patent FR3049979A1

Train de machines pour produire de l'acide nitrique, comprenant une turbine à vapeur pourvue d'un rotor de turbine à vapeur, qui est conçu pour tourner à une vitesse de rotation n10, un premier compresseur pourvu d'un premier rotor de compresseur, qui est conçu pour tourner à une vitesse de rotation n20, un deuxième compresseur (30) pourvu d'un deuxième rotor de compresseur, qui est conçu pour tourner à une vitesse de rotation n30, un dilatateur (40) pourvu d'un rotor de dilatateur, qui est conçu pour tourner à une vitesse de rotation n40, dans lequel la turbine à vapeur est conçue comme une unité d'entraînement pour le premier compresseur et dont le rotor est connecté de façon opérationnelle au rotor du premier compresseur par l'intermédiaire d'un premier couplage, dans lequel le rotor du premier compresseur est connecté de façon opérationnelle au rotor du deuxième compresseur par l'intermédiaire d'un deuxième couplage et entraîne le deuxième compresseur, dans lequel le dilatateur est conçu comme une unité d'entraînement pour le deuxième compresseur (30) et le rotor de celui-ci est connecté de façon opérationnelle au rotor du deuxième compresseur par l'intermédiaire d'un troisième couplage, caractérisé en ce que le deuxième compresseur est conçu par rapport à sa vitesse de rotation optimisée en rendement n30 de telle manière que pendant le fonctionnement du train de machines, les vitesses de rotation n10 de la turbine à vapeur, les vitesses de rotation n20 du premier compresseur, les vitesses de rotation n30 du deuxième compresseur et les vitesses de rotation n40 du dilatateur soient égales. A machine for producing nitric acid, comprising a steam turbine provided with a steam turbine rotor, which is adapted to rotate at a rotation speed n10, a first compressor provided with a first compressor rotor, which is adapted to rotate at a rotation speed n20, a second compressor (30) provided with a second compressor rotor ...

Device for needling a mattress.

Il est décrit un dispositif pour aiguilleter un matelas, avec un mécanisme à bielle-manivelle (6) agissant sur un balancier (10), pour entraîner au moins une planche à aiguilles (2) fixée sur le balancier (10) et avec un guidage de matelas (14), constitué d'une base de piquage (4) placée en face de la planche à aiguilles (2) et d'un racleur (5) disposé entre la base de piquage (4) et la planche à aiguilles (2). Pour pouvoir influencer le résultat de l'aiguilletage, il est proposé que l'inclinaison moyenne des trajectoires de piquage (13, 13a, 13b) des aiguilles (3) de la planche à aiguilles (2) dans le matelas soit réglable par rapport à la direction d'avancement (12) du matelas. A device is described for needlepointing a mattress, with a connecting rod-crank mechanism (6) acting on a balance (10), for driving at least one needle board (2) fixed on the balance (10) and with a guide. mattress (14), consisting of a stitching base (4) placed in front of the needle board (2) and a scraper (5) placed between the stitching base (4) and the needle board ( 2). In order to be able to influence the result of the needling, it is proposed that the average inclination of the stitching paths (13, 13a, 13b) of the needles (3) of the needle board (2) in the mattress be adjustable with respect to the direction of advance (12) of the mattress.

Window locking mechanism actuator rod - is connected to corner connectors by detachable connection involving pins and holes

The locking mechanism for windows or doors has actuating rods connected to corner guides, locks and tilting mechanism locks. This mechanism can be used for forming accurate lengths for prefabricated locking arrangements for windows and doors. The covering profile of the actuating rod drive can be shortened and it is rivetted to the adjacent angle profile. Actuating rod connecting piece can be connected to the corner guide by means of the covering angle profile end, which overlaps the actuating rod and it projects beyond this and it can be connected by means of a number of connecting holes and connecting pins for forming a detachable connection.

Power control system

Immersion pump for handling waste water - with combination of two electric motor units to improve performance

Method and system for transmitting data in an air pressure control system of a motor vehicle

High reduction transmission

Cutting device for paper, cardboard or similar materials

For the deflection of movement of the connecting rods, in particular of tilt-swivel wing fittings for windows, doors or the like, corner deflection

Pivot for wings of windows, doors or the like arranged to be both swingable about a vertical axis and tiltable about a horizontal axis

Needling device for a fiber mat.

Il est décrit un dispositif d'aiguilletage d'un matelas de fibres, avec un mécanisme à bielle-manivelle (6), agissant sur balancier (10), pour entraîner au moins une planche à aiguilles (2), fixée sur le balancier (10) et dont les aiguilles (3) comprennent une tige (14) et une partie travailleuse (16). Pour assurer des conditions d'enfichage avantageuses, il est proposé que la partie travailleuse (16) des aiguilles (3) soit incurvée le long d'un arc de cercle dans un plan perpendiculaire par rapport à l'axe de rotation (11) du balancier (10), arc de cercle dont le centre est situé dans la zone de l'axe de rotation (11) du balancier (10). A needling device for a fiber mat is described, with a connecting rod-crank mechanism (6), acting on the balance (10), to drive at least one needle board (2), fixed on the balance ( 10) and whose needles (3) comprise a rod (14) and a working part (16). To ensure advantageous plugging conditions, it is proposed that the working part (16) of the needles (3) be curved along an arc of a circle in a plane perpendicular to the axis of rotation (11) of the balance (10), arc of a circle whose center is located in the area of the axis of rotation (11) of the balance (10).

Mold release agent for polyamide molding compounds

MACHINE FOR NEEDLING A FIBER WEB.

Pour pouvoir munir la planche à aiguilles (1) d'une machine à aiguilleter les voiles de fibres d'une plus grande densité d'aiguilles, afin d'améliorer la conformation de surface du voile formé, les aiguilles (2) de la planche à aiguilles (1) sont réunies en groupes d'une grande densité d'aiguilles et, à chacun de ces groupes d'aiguilles est associée une ouverture de passage commune (7) de la plaque perforée (5) du dévêtisseur (4) ou de l'appui de piqûre (3), les aiguilles (2) d'un même groupe étant disposées avec un décalage transversal mutuel dans une rangée longitudinale, considéré relativement à la direction (6) du défilement du voile. In order to be able to provide the needle board (1) with a needling machine for the veils of fibers with a greater density of needles, in order to improve the surface conformation of the formed veil, the needles (2) of the board with needles (1) are combined into groups of a high density of needles and, to each of these groups of needles is associated a common passage opening (7) of the perforated plate (5) of the stripper (4) or of the stitching support (3), the needles (2) of the same group being arranged with a mutual transverse offset in a longitudinal row, considered relative to the direction (6) of the movement of the web.

HINGE JOINT FOR WINDOWS, DOORS OR. DGL

Tool i.e. screwdriver, for workpiece, has coupling element arranged between grab handle and tool shank, and rotatably-fixed connection produced during press on grab handle in direction of operating end of tool shank by coupling element

The tool has a tool shank (20) movably guided along a longitudinal axis (A) relative to a grab handle (10). A coupling element (30) is arranged between the grab handle and the tool shank. A rotatably-fixed connection between the grab handle and the tool shank is produced during press on the grab handle in a direction of an operating end (24) of the tool shank by the coupling element. The tool shank is freely-rotatably mounted in the grab handle without press in the direction of the operating end. A springy element (40) is arranged between the tool shank and the grap handle.

From a wing fitting part and a frame fitting part existing fitting for windows, doors or the like.

Sampling device for liquids esp. alkyl aluminium cpds. - has inert gas supply and hose clamps to permit sampling without ingress of air

Appts. for taking samples of air-sensitive liquids, esp. Al alkyl cpds. consists of the following components. A sampling tube with a lock nut and conical cap mounted on its head the cap having a nipple for attachment of a tube, a flask with lock nut and plug. The flasks rests in a dish or container with a downward pin for mounting it, An inert gas nipple connection branches from the head of the flask. A 3-ring injection syringe. A hose or tube is connected at one end to the nipple on the cap of the tube and can be closed by a hose clamp. This tube leads to an inert gas supply at a branch, while a further branch tube connects the inert gas supply to the nipple on the neck of the flask. The latter connection is also closed by a hose clamp. The 3-ring syringe is connected by a further hose to the length of hose between the clamp and the inert gas connection to the flask.

Guide for flexible bone drill and bone resection instrument

A guide for flexible bone drill comprises a first body (2) provided internally with a through channel (4), and a second body (3), that is internally hollow, into which the first body (2) can be inserted. The second body is provided with a through hole (6) suitable to be placed in fluidic connection with the through channel (4) of the first body (2). The second body (3) and the first body (2) slide relative to one another to vary the relative position of the hole (6) with respect to the through channel (4), thus changing the exit angle of the flexible bone drill (10) which is inserted into the through channel (4) in the first body (2) and emerges from the through hole (6) in the second body (3).

Key ring

Bag to hold a photograph or the like

RING SPINNING DEVICE.

L'invention se rapporte à la filature. Pour garantir l'obtention de conditions de filage avantageuses pour un dispositif de filage à anneau, on prévoit dans la région de l'anneau de guidage (5) qui reçoit un curseur (4), une piste de renvoi (10) qui encercle l'axe de la broche, pour renvoyer le fil (3) arrivant au curseur (4), le brin de fil (3) arrivant de la piste de renvoi (10) au curseur (4) formant avec le brin de fil (3b) qui part du curseur (4), un angle aigu (alpha) dans la région du curseur, en projection dans un plan qui contient l'axe de la broche. Principale application: filage de fil à grande vitesse. The invention relates to spinning. To ensure that advantageous spinning conditions are obtained for a ring spinning device, there is provided in the region of the guide ring (5) which receives a slider (4), a return track (10) which encircles it. 'axis of the spindle, to return the wire (3) arriving at the cursor (4), the wire strand (3) arriving from the return track (10) to the cursor (4) forming with the wire strand (3b) which starts from the cursor (4), an acute angle (alpha) in the cursor region, projecting into a plane that contains the axis of the spindle. Main application: high speed wire spinning.

Carburetor for internal combustion engines

Web printing means

Tool handle

The invention relates to a tool handle (1) having a cover (3) that can be pivoted out of the handle (1), in which a holder (5) for tool components (15) is disposed, the holder (5) being rotatably supported in the cover (3).

Ball joint with internal universal joint

Process for the preparation of aqueous dispersions of vinyl ester polymers

Process for the production of molding compounds with improved impact strength at low temperatures based on polypropylene

LEAF LOCKING DEVICE FOR WINDOWS, DOORS OR DGL

Device for manufacturing a fiber mat.

Pour améliorer l'homogénéité de la désolidarisation des fibres par rapport au tambour de cardage il est prévu, dans la zone de la limitation de côté amenée du canal, un rouleau travailleur (5) coopérant avec le tambour de cardage (1), rouleau travailleur entre lequel et le tambour de cardage (1), du côté opposé au canal d'aspiration (3), débouche un canal d'amenée (5) destiné à un courant d'amenée d'air, aspiré à travers la fente très étroite existant entre le tambour de cardage (1) et le rouleau travailleur (5). To improve the homogeneity of the separation of the fibers with respect to the carding drum, a working roller (5) cooperating with the carding drum (1) is provided in the zone of the side limitation supplied with the channel. between which and the carding drum (1), on the side opposite to the suction channel (3), opens a supply channel (5) intended for an air supply stream, sucked through the very narrow slot existing between the carding drum (1) and the worker roller (5).

Pre-registration system for board placement

The present invention provides an apparatus and method for pre-registering boards for use in, for example, the manufacture of looseleaf binders and packaging products. Boards are dropped onto the base plate by an automatic process. Spine guides enable the spine portion of the boards to be secured for subsequent registering. The movement of the spine guides allows the spine portion of the boards to be placed accurately. The spine guides are attached to a spine guide rack which is located on the underside of the base plate. The spine guide rack operates through the use of pneumatic cylinders and enables the movement of the attached spine guides. The spine guides move along a spine guide trench and secure boards on the base plate. The spine guides are retracted when the boards are initially placed on the base plate and then start moving medially to squeeze the spine portion of the board such that it becomes perpendicular to the x-axis. The spine guides also allow for the requisite spacing in between the spine panel and the front and back board panels. This securing apparatus which includes, among other things, the movable guide bars and spine guides, enables the placement of boards and the subsequent binding process to be within desired tolerances. Once the spine guides have set the spine portion of the boards, movable guide bars begin pushing the front and back panels medially towards the y-axis. The movable guide bars will cease movement when the medial edge of the board panel comes into contact with the lateral edge of the spine guides. At this point, the movable guide bars-fixed perpendicular to the x-axis-will correct the panel positions such that the medial panel edges will achieve substantial perpendicularity with the x-axis.

Process for the immobilization of proteins on an implant

The present invention refers to the chemical functionalisation of surfaces, in particular ceramic materials, particularly such comprising hydroxyapatite, and the use of tensides for improving the absorption characteristics of metallic or ceramic surfaces.

Process for structuring a photoresist layer

Verfahren zur Strukturierung einer Photolackschicht, umfassend die Schritte: a) ein Substrat wird bereitgestellt, auf dem zumindest in Teilbereichen eine Photolackschicht aufgebracht ist, wobei die Photolackschicht aa) ein filmbildendes Polymer, das Molekülgruppen umfasst, die durch sauer katalysierte Abspaltungsreaktionen in alkalilösliche Gruppen überführt werden können, und ab) einen Photobasengenerator, der bei Bestrahlung mit Licht aus einem definierten Wellenlängenbereich eine Base freisetzt, umfasst, b) die Photolackschicht wird in Teilbereichen mit Licht aus dem definierten Wellenlängenbereich bestrahlt, c) die Photolackschicht wird über einen bestimmten Zeitraum mit einer Säure in Kontakt gebracht, wobei die Säure in die Photolackschicht diffundiert, d) die Photolackschicht wird auf eine Temperatur erhitzt, bei der die sauer katalysierte Abspaltungsreaktion erfolgt, e) die Photolackschicht wird entwickelt. Process for structuring a photoresist layer, comprising the steps: a) a substrate is provided on which a photoresist layer is applied at least in some areas, wherein the photoresist layer aa) a film-forming polymer comprising molecular groups which can be converted by acid-catalyzed cleavage reactions into alkali-soluble groups, and ab) a photobase generator which releases a base upon irradiation with light from a defined wavelength range, comprising b) the photoresist layer is irradiated in partial areas with light from the defined wavelength range, c) the photoresist layer is contacted with an acid for a certain period of time, the acid diffusing into the photoresist layer, d) the photoresist layer is heated to a temperature at which the acid catalyzed cleavage reaction takes place, e) the photoresist layer is developed.

Method and apparatus for determining audience viewing habits

METHOD AND APPARATUS FOR DETERMINING AUDIENCE VIEWING HABITS A tract of the Disclosure A method and apparatus for determining the channel of a plurality of predetermined channels to which a remotely controlled receiver is tuned. A viewer transmitter device includes a keyboard for receiving viewer entered selections and a remote trans-mitter which transmits infrared, ultrasonic, radio frequency or other radiated control signals for each of the viewer selections. A receiver device in a channel detection system receives a signal in the selected transmission medium, and immediately signals a jamming device to broadcast interference which pre-cludes the remotely controlled receiver from identifying and acting upon the transmitted control signal. The receiver device applies the received signal to a processor device that performs a stored program to determine if the received signal corresponds to a transmitted control signal from the viewer transmitter device and, if so, to identify the channel to which the monitored receiver is to be tuned. An associated memory device is used for storing the identified channel reception data. The processor device identifies the user selection and either applies a corresponding control signal to a second transmitter device which transmits a control signal of sufficient strength to overcome the inter-ference, or instructs the jamming device to cease the broadcasting of interfering signals. In either case, the remotely controlled receiver will now receive and implement the viewer selection. The processor device will periodically broadcast a command to the remotely controlled receiver containing the last identified channel data to ensure that a viewer does not manually adjust the channel being viewed.

YARN PRODUCTION DEVICE

Process for the preparation of 3-bromo-4- fluorotoluene

Bayer 4607-LH Le A 20 210-US Rt/B?t ABSTRACT In the preparation of 3-bromo-4-fluorotoluene by reacting 4-fluorotoluene with bromine, the improvement which comprises effecting the bromination in glacial acetic acid in the presence of iodine and iron or an iron salt. As a result the proportion of 3-bromo-4-fluorotoluene relative to its 2-bromo-4-fluorotoluene isomer is markedly increased.

Alloy resistance element and method for manufacturing same

Herbicidal cycloalkyl-substituted thiadiazolyloxyacetamides

Herbicidal cycloalkyl-substituted thiadiazolyloxyacetamides of the formula ##STR1## in which R 1 represents hydrogen, or represents an optionally substituted radical selected from the group consisting of alkyl, alkenyl, alkynyl and aralkyl, R 2 represents an optionally substituted radical selected from the group consisting of alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, aralkyl, aryl, alkoxy, alkenyloxy and alkynyloxy, or R 1 and R 2 , together with the nitrogen atom to which they are bonded, form an optionally substituted saturated or unsaturated nitrogen-heterocyclic radical, which can contain further hetero atoms and to which a benzo grouping can be fused, and R 3 represents optionally substituted cycloalkyl. Intermediates of the formula ##STR2## are also new.

Control valve for air brakes, preferably of the multiple type for rail vehicles

Door or window edge lock - has path of motion of connecting rod or locking pin bounded by half path motion directions

An edge lock for doors and windows having flaps linked to the static frames, especially rotating flaps, has the overall motion path (7) of the connecting rod (2) or the bolt pin (3) relative to the inverting beam (1) describing a 180 deg. rotation of the activating lever (8). As a result between the connecting rod (2) and the inverting beam (1) an adjustable striker device (9) is situated built into the edge lock, and over which the effective path of motion (7/2) of the connecting rod (2) or bolt pin (3) at its mid motion point can be bounded either by one or the other directions of motion of half of the total path of motion (7).

Process for structuring a photoresist layer

Beschrieben wird ein Verfahren zum Strukturieren einer Photolackschicht, das die folgenden Schritte umfasst: Ein Substrat wird bereitgestellt, auf dem zumindest in Teilbereichen eine Photolackschicht aufgebracht ist. Die Photolackschicht umfasst ein filmbildendes Polymer, das Molekülgruppen aufweist, die durch sauer katalysierte Abspaltungsreaktionen in alkalilöslichen Gruppen überführt werden können. Weiterhin umfasst das Polymer einen Photosäuregenerator, der bei Bestrahlung mit Licht aus einem definierten Wellenlängenbereich DELTAlambda¶1¶ eine Säure freisetzt. Daneben umfasst das Polymer einen Photobasengenerator, der bei Bestrahlung mit Licht aus einem definierten Wellenlängenbereich DELTAlambda¶2¶ eine Base freisetzt. Die Photolackschicht wird zunächst in Teilbereichen mit Licht aus dem definierten Wellenlängenbereich DELTAlambda¶2¶ bestrahlt, wobei die Wellenlänge des Lichts so gewählt ist, dass der Photosäuregenerator im Wesentlichen inert gegen die Bestrahlung ist. Anschließend wird die Photolackschicht mit Licht aus dem definierten Wellenlängenbereich DELTAlambda¶1¶ bestrahlt, wobei die Wellenlänge des Lichts so gewählt ist, dass der Photobasengenerator im Wesentlichen inert gegen die Bestrahlung ist. Daneben wird die Photolackschicht auf eine Temperatur erhitzt, bei der die durch die photolytisch erzeugte Säure katalysierte Abspaltungsreaktionen erfolgt und schließlich wird die Photolackschicht entwickelt. A method for structuring a photoresist layer is described, which comprises the following steps: A substrate is provided on which a photoresist layer is applied at least in partial areas. The photoresist layer comprises a film-forming polymer which has groups of molecules which can be converted into alkali-soluble groups by acid-catalyzed cleavage reactions. Furthermore, the polymer comprises a photo acid generator which releases an acid when irradiated with light from a defined wavelength range DELTAlambda¶1¶. In addition, the polymer includes a ...

Process for the production of furan derivatives

Pole mount

Chemically amplified short wavelength resist

A resist capable of imaging by exposure to radiation having a wave length of about 157 nm includes an imagewise convertible film-forming polymer substituted with at least one chemical functional deblocking group cleavable under acid-catalyzed baking conditions to form polar groups imparting solubility of the deblocked polymer in aqueous alkaline developer. At least one photo acid generator compound releases an acid upon exposure to radiation and catalyzes the cleavage of the deblocking groups. An effective amount of at least one radical scavenger compound is used to minimize reactions decreasing the solubility of the deblocked polymer in aqueous alkaline developer. At least one solvent is also provided.

Process for the preparation of basic substituted 9,10-dihydro-4H-benzo [4,5] cyclo-hepta [1,2-b] thiophenes

Container with sight-glass

The arrangement of a sight-glass (2) in the wall (1) of a container, which serves to take up reactive or flammable liquids or liquids otherwise damaging to health, represents a potential source of danger in the case of a glass breakage connected with an uncontrolled emergence of liquid. For this purpose, the sight-glass is covered in a sealing fashion with an outer cap. In the sight-glass arrangement according to the invention, the sight-glass (2) is received in a fully protected manner in a recess in a receiving body welded to the wall (1) of the container and is retained in this recess by means of a holding body. A threaded pipe element (16) is welded to the holding body, and carries on its end face a closure cap (17). By means of an axially extending groove (20) which is recessed in the outer surface of the threaded pipe element (16) and dimensioned to be longer than the outer thread serving to screw on the closure cap (17), a negligible emergence of liquid is allowed by a slight loosening of the closure gap (17) if the glass is broken, this indicating the defective sight-glass (2). <IMAGE>

Gas burner

LEAK DETECTOR FOR SEALED ROOMS

New cinnamic acid derivatives useful as insecticide intermediates

Halo-substituted o-carboxycinnamic acid derivatives (I) are new. Cinnamic acid derivatives of formula (I) are new: X = F, Cl or I; R<1>, R<2> = H, optionally substituted 1-10C alkyl or optionally substituted benzyl. An Independent claim is also included for the preparation of (I).

FOERFARANDE FOER FRAMSTAELLNING AV BENSOESYRADERIVAT.

Pneumatic dust-arrester installation

Process for the preparation of substituted thiocarbamic acid esters

Process for the preparation of new heterocyclic compounds

Screw driver, has clamping device designed such that relative movement between shaft and drive portion is locked, when drive portion lie against torque, so that automatic locking is controlled by rotation of another drive portion

The screw driver has a handgrip comprising drive portions (11, 12), and a shaft (2) arranged coaxial to the drive portions and passed through the drive portions. A self locking clamping device is connected with one of the drive portions and the shaft in a self-lock manner. The clamping device is designed such that a relative movement between the shaft and the drive portion of the handgrip is locked, when the drive portion lie against rotational torque, such that automatic locking is controlled by rotation of another drive portion.

SUBSTITUTED OXIMETERS, THEIR PREPARATION AND USE AS A PESTICIDANT

Process for the preparation of 1,3,4,9b-tetrahydro-2,5-dimethyl-2H-indeno (1,2-c) pyridine

CORNER RETURN DEVICE FOR FITTINGS WITH ACTIVE RODS OR CONTROL RODS

Bottle sealing method and apparatus

An embossed seal is formed in a cavity in the neck of a corked bottle over a cork using a die having a die surface with a die image. A first molten seal material is introduced into a die cavity. The die cavity is formed in part with the die surface. The introduction of the first molten seal material deposits an embossed seal portion with an embossed surface. The embossed seal portion is allowed to cool. A second molten seal material is introduced into the cavity of the neck of the corked bottle. The embossed seal portion is brought into contact with the molten seal material in the bottle cavity with the embossed surface disposed on top facing away from the molten seal material. The molten seal material partially melts the embossed seal portion to form a single seal upon cooling. The embossed seal portion is sufficiently cooled and solidified to prevent melting and damage of the embossed surface. An automated apparatus is provided for carrying out the two-stage procedure of forming the seal to produce high quality embossed seals at an economically desirable rate. A die truck assembly is used to form the embossed seal portion. The assembly includes three springs to provide a triple telescoping action that allows the assembly to be engaged with the bottle necks and maintains the engagement along a specific travel path to form the seal to seal the bottle. The triple telescoping action also releases the embossed seal portion from the die cavity of the die truck assembly into the molten seal material in the cavity over the cork in the bottle neck. It further allows the die truck assembly easily to self-adjust and compensate for varying bottle heights and varying cork heights so as to exert a generally consistent pressure on the embossed seal portion and molten seal material to form the finished seal.

Method for suppressing the return flow in a waveguide

Process for the preparation of new 3,5-diketopyrazolidines

WIRING

Machine for manufacturing pads bound with a spiral wire

Device for the retraction of soft tissue in a patient undergoing arthroscopic surgery

A device for the retraction of soft tissue in a patient undergoing arthroscopic surgery, comprising a pulling element extending in its own main direction between a first end and a second end, the latter being fitted with a hooking body configured to pass through the soft tissue of a patient and engage in the soft tissue following the traction of the pulling element towards the first end. The device further comprises a presser body suitable to press on the skin of the patient and connectable to the pulling element in at least one operating position placed at a fixed distance from the second end, wherein the fixed distance is such as to define a housing for the layers of soft tissue of the patient engaged by the hooking body.

Checking means for automatic workpiece orientation

Axial pressure ball bearing

1-(2-trifluoromethoxy-phenylsulphonyl)-3-heteroaryl- (thio)ureas

ABSTRACT 1-(2-Trifluoromethoxy-phenylsulphonyl)-3-heteroaryl-(thio)urea herbicides of the formula

Espagnolette fastening for the bottom-closing wing of two-wing windows or doors without a mullion

Fastened to the circumferential surface of the rebate of the bottom-closing wing is a cover rail (7), behind which an espagnolette (8) received by a groove of the wing is guided displaceably for the purpose of actuating bolt members. Mounted pivotably on the outside of the cover rail (7) and parallel to the main plane of the latter is an operating lever (13), on which is articulated at one end a tab (17) which, via its other end, engages on the espagnolette (8) through a longitudinal slot (20) of the cover rail (7). The operating lever (13) is fastened fixedly in terms of rotation to the crank pin (14) of a crank arm (15) mounted on the outside of the cover rail (7) via a journal (16), and one end of the tab (17) is connected in an articulated manner to the crank pin (14) between the crank arm (15) and the operating lever (13). This espagnolette fastening guarantees, along with a small installation space, reliable actuation with little effort. <IMAGE>

Pneumatic cleaning system for textile machines with cable connection

PASS-THROUGH CONNECTIONS.

CURRENT TRANSFORMER FOR MEASURING CURRENT LEVELS, IN PARTICULAR IN HIGH VOLTAGE LINES

Herbicidal novel 1-(2-trifluoromethoxy-phenylsulphonyl)-3-heteroaryl-(thio)ureas

1-(2-Trifluoromethoxy-phenylsulphonyl)-3-heteroaryl-(thio)urea herbicides of the formula ##STR1## in which Q represents oxygen or sulphur, R 1 represents hydrogen, C 1 -C 4 -alkyl or benzyl, R 2 represents hydrogen, halogen, hydroxyl, C 1 -C 4 -alkyl, C 1 -C 4 -halogenoalkyl, C 1 -C 4 -alkoxy, C 1 -C 4 -halogenoalkoxy, C 1 -C 4 -alkylthio, C 1 -C 4 -halogenoalkylthio, amino, C 1 -C 4 -alkylamino or di-(C 1 -C 4 -alkyl)-amino, X represents nitrogen or a --CH-- grouping, Y represents nitrogen or a --CR 3 -- grouping, wherein R 3 represents hydrogen, halogen, C 1 -C 4 -alkyl, (C 1 -C 2 -alkyl)-carbonyl or (C 1 -C 2 -alkoxy)-carbonyl, and Z represents nitrogen or a --CR 4 -- grouping, wherein R 4 represents hydrogen, halogen, hydroxyl, C 1 -C 4 -alkyl, C 1 -C 4 -alkoxy, C 1 -C 4 -alkylthio, C 1 -C 4 -alkylamino or di-(C 1 -C 4 -alkyl)-amino.

Process for the production of quaternary ammonium salts of esterified 6-alkoxydropine

Brake cylinder

Plastic microscope slides

MOLDED BODY IN POTASSIUM SUPEROXIDE

UN CORPS MOULE CONSTITUE DE SUPEROXYDE DE POTASSIUM COMME SUBSTANCE CHIMIQUE CEDANTE D'OXYGENE, AVEC ADDITION DE MATERIAU CATALYSEUR ACTIVANT LA CESSION D'OXYGENE, DOIT ETRE AMELIORE DE TELLE SORTE QUE PUISSE SE PRODUIRE UNE FIXATION CONCENTREE DU MATERIAU CATALYSEUR SUR LA SURFACE DU CORPS MOULE, PERMETTANT UNE LIBERATION REGULIERE D'OXYGENE PENDANT LA TOTALITE DU TEMPS D'UTILISATION. CELA DOIT ASSURER UNE SEPARATION D'OXYGENE ADAPTEE AUX BESOINS DES LE DEBUT DE L'UTILISATION DE L'APPAREIL DE PROTECTION RESPIRATOIRE, ET EMPECHER UNE DELIVRANCE D'OXYGENE SUPERIEURE AUX BESOINS AU COURS DE LA POURSUITE DE L'UTILISATION. UN TEL CORPS MOULE EST CONSTITUE D'UN CORPS CENTRAL COMPRIME 1 A TENEUR EN CATALYSEUR DE 0 A 0,05, ENTOURE D'UNE ENVELOPPE COMPRIMEE 2 A TENEUR EN CATALYSEUR DE 0,15 A 2,0. APPLICATION A L'EQUIPEMENT D'APPAREILS RESPIRATOIRES. A MOLDED BODY CONSISTING OF POTASSIUM SUPEROXIDE AS A CHEMICAL SUBSTANCE LOWING OXYGEN, WITH THE ADDITION OF CATALYST MATERIAL ACTIVATE THE OXYGEN LOSS, MUST BE IMPROVED SUCH AS A FIXATION OF THE CONCENTRATED MATERIAL ON THE CATALYST MAY OCCUR. , ALLOWING A REGULAR RELEASE OF OXYGEN DURING THE ENTIRE USE TIME. THIS MUST ENSURE AN ADAPTABLE OXYGEN SEPARATION FROM THE BEGINNING OF USE OF THE RESPIRATORY PROTECTION DEVICE, AND PREVENT A DELIVERY OF OXYGEN EXCEEDING NEEDS DURING CONTINUED USE. SUCH A MOLDED BODY CONSISTS OF A COMPRESSED CENTRAL BODY 1 WITH A CATALYST CONTENT OF 0 TO 0.05, SURROUNDED BY A COMPRESSED ENVELOPE 2 WITH A CATALYST CONTENT OF 0.15 TO 2.0. APPLICATION TO RESPIRATORY EQUIPMENT.

RIBBERS WITH PROTUVERANZ

Device for mounting and removing belts

Process for the preparation of new 1-amino-2,4-dioxo-azetidine derivatives

Adaptor having a coupling-on device for optical fibres

A coupling-on device is integrated in the adaptor. Through a gap (75) existing between the ends of the two fibres (39, 51), the optical signals arriving in one fibre (39) are transmitted onwards in the other fibre (51) not only in the core mode but also partly in the clamping mode. An extractor (52) mounted on the fibre is used to extract the light beams from the fibre cladding and direct them via a reflector device (53) onto a photodetector (55), so that a coupled-out electric signal (S) is available at the adaptor. The width of the gap (75), and thus the latitude of the coupled-out signal, can be varied by using interlayers of different thicknesses between the adaptor halves. <IMAGE>

Process for the preparation of new phenothiazine derivatives

Container with a safety valve

Tilt and turn fitting for windows, doors or similar room closures

Process for the production of solid fuel from a process for the production of solid fuel from the residues resulting from the petroleum refinery. arrears.