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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 7516. Отображено 100.
12-01-2012 дата публикации

Compartment Syndrome Monitoring Systems and Methods

Номер: US20120010525A1
Автор: David J. Jacofsky, John P. Peeters, Marc C. Jacofsky
Принадлежит: TCI3 Pressure Applications LLC

Embodiments of a compartment monitor that can be implanted and left in situ to continuously (or semi-continuously) measure compartment pressures are presented. An exemplary monitor includes a pressure sensor adapted to be implanted in a compartment, a transmitter external to the compartment and coupled to the pressure sensor, and a receiver in communication with the transmitter to receive and process pressure data received from the transmitter. The monitor may also be configured to transmit measured pressure data to a networkable device. The networkable device can then communicate the patient's status and condition to a healthcare provider through a local area network (LAN) or wide area network (WAN). This communication allows the healthcare provider to remotely monitor a patient. The networkable device, or associated computing system, can record and display trends in the pressure data over time, and log the data to the patient's electronic health records.

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Номер записи: 1
09-02-2012 дата публикации

Catheter, a balloon catheter and a method and apparatus for monitoring the transverse cross-section of a stoma

Номер: US20120035642A1
Автор: Adrian Mchugh, Eoin Bambury, John O'dea
Принадлежит: Flip Technologies Ltd

A balloon catheter ( 1 ) comprises a catheter ( 2 ) and a balloon ( 6 ) located on the distal end of the catheter. A pair of stimulating electrodes ( 15 ) for receiving a constant current stimulating signal when the balloon ( 6 ) is inflated with an electrically conductive medium and a plurality of sensing electrodes ( 16 ) for producing voltage response signals are located on the catheter ( 2 ). The voltage response signals are indicative of the values of the transverse cross-sectional area of the balloon ( 6 ) adjacent the sensing electrodes ( 16 ). A first lumen < 9 ) accommodates the inflating medium to and from the balloon ( 6 ), and a second lumen ( 19 ) accommodates electrically conductive wires ( 18 ) to the stimulating and sensing electrodes ( 15,16 ). A pressure sensing dement ( 21 ) is located in a protective housing ( 22 ) in the second lumen ( 19 ), and communicates through a communicating opening ( 26 ) in the protective housing ( 22 ) and through a communicating port ( 24 ) in the catheter ( 2 ) with a hollow interior region ( 7 ) of the balloon ( 6 ).

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Номер записи: 2
16-02-2012 дата публикации

Catheter with thin film pressure sensing distal tip

Номер: US20120041295A1
Автор: Jeffrey W. Schultz
Принадлежит: Biosense Webster Inc

A mapping and ablation catheter has contact force sensing capabilities at a distal end. In one embodiment, the catheter includes a catheter body, a deflectable section, and a tip distal tip section which has a tip electrode with a thin-film pressure sensor that is adapted to detect a force vector applied to the tip electrode. The thin-film pressure sensor includes two opposing flexible and thin support members containing a pressure-sensitive material therebetween whose resistivity changes as a result of pressure and is detected by trace electrode intersections supported on interfacing surfaces of the flexible and thin support members. Used with a stop member having a conforming shape against which the thin-film pressure sensor abuts when a force vector is applied to the tip electrode, the pressure sensor can have a 2-D, radially-symmetrical shape, e.g., a disc or ring configuration, or a 3-D, radially-symmetrical shape, e.g., a conical configuration.

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Номер записи: 3
22-03-2012 дата публикации

Methods and systems for determining vascular bodily lumen information and guiding medical devices

Номер: US20120071782A1
Автор: Goutam Dutta, Nitin Patil, Raghavan Subramaniyan
Принадлежит: Angiometrix Corp

Methods and systems for determining information about a vascular bodily lumen are described. An exemplary method includes generating an electrical signal, delivering the electrical signal to a plurality of excitation elements in the vicinity of the vascular bodily lumen, measuring a responsive electrical signal from a plurality of sensing elements in response to the delivered electrical signal, and determining a lumen dimension. Specific embodiments include generating a multiple frequency electrical signal. Another embodiment includes measuring a plurality of responsive signals at a plurality of frequencies. Still other embodiments include using spatial diversity of the excitation elements. Yet other embodiments use method for calibration and de-embedding of such measurements to determine the lumen dimensions. Diagnostic devices incorporating the method are also disclosed, including guide wires, catheters and implants. The methods and systems described herein are advantageous as they do not include injecting a second fluid for the measurements.

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Номер записи: 4
29-03-2012 дата публикации

Systems and methods for analysis and treatment of a body lumen

Номер: US20120078121A1
Автор: Jing Tang, Richard Gambale, S. Eric Ryan
Принадлежит: Cornova Inc

A catheter for placement within a body lumen, the catheter including a flexible conduit that is elongated along a longitudinal axis, the flexible conduit having a proximal end and a distal end, at least one delivery waveguide and at least one collection waveguide extending along the flexible conduit, a lumen-expanding inflatable balloon disposed about a portion of the conduit, a transmission output of the at least one delivery waveguide and a transmission input of the at least one collection waveguide located within the balloon; and, at least one elongate arm connected to the conduit and positioned within the balloon, the at least one elongate arm radially translatable with respect to the conduit, and wherein at least one of the transmission output and transmission input is coupled to the elongate arm.

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Номер записи: 5
10-05-2012 дата публикации

Automated adaptive muscle stimulation method and apparatus

Номер: US20120116478A1
Автор: David Truffer, Felix Buhlmann, Klaus Schonenberger, Pierre Rigaux, Pierre-Yves Lampo, Pierre-Yves Müller
Принадлежит: Compex Medical SA

An automated adaptive muscle stimulation system and method are disclosed. The stimulation system includes at least one electrode assembly adapted to deliver a muscle stimulation signal to the tissue of a user, a sensor system adapted to detect a muscle response, and an electrical stimulation device operably coupled to the at least on electrode assembly and the sensor system, the electrical stimulation device including a control system operable to automatically diagnose at least one characteristic of a muscle from the detected muscle response and adjust at least one parameter of the muscle stimulation signal in response thereto to deliver an adjusted muscle stimulation signal. A dual mode muscle stimulation system adapted to accept first and second data sets and provide first and second levels of treatment data is also disclosed.

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Номер записи: 6
05-07-2012 дата публикации

System for continuous measuring, recording and monitoring of the splanchnic tissue perfusion and the pulmonary physiological dead space, and use thereof

Номер: US20120172683A1
Автор: Juan Ingacio Muñoz Bonet
Принадлежит: Individual

The present invention relates to a new system for measuring, recording and monitoring the splanchnic tissue perfusion and the pulmonary physiological dead space in an automated way, both continuously and intermittently, and in real time, which is easy to manage and generates information easy to interpret. Said system comprises at least four measuring devices of medical parameters, connected to a device receiving, converting, storing, integrating, processing, and allowing the management and display of the data recorded in the measurements and the parameters estimated by the same. For this purpose, said device comprises a specific computer program of estimation of parameters related to the measurement of the splanchnic tissue perfusion and the pulmonary physiological dead space, from the data derived from the measuring devices. Likewise, the present invention is related to the use of a device for measuring, recording and monitoring of the splanchnic tissue perfusion and the pulmonary physiological dead space.

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Номер записи: 7
02-08-2012 дата публикации

Apparatus and methods for treating obstructions within body lumens

Номер: US20120197193A1
Автор: Gwendolyn Watanabe, Jeffrey A. Krolik, Juan Domingo, Lucas Fernandez, Ray Betelia
Принадлежит: Hotspur Technologies LLC

Apparatus and methods are provided for delivering fluid into a body lumen during a medical procedure. A distal end of an apparatus may be introduced into a body lumen, and a valve on the distal end may be opened to deliver fluid through a first lumen into the body lumen, e.g., contrast and/or other diagnostic or therapeutic agents. The valve may be closed, and a procedure may be performed within the body lumen, e.g., using a treatment element carried on the distal end. For example, the treatment element may include a balloon that may be inflated when fluid is delivered through the first lumen with the valve closed. Optionally, a prosthesis, energy source, drug platform, and the like may be carried by the balloon for treating the body lumen. In various embodiments, the valve may be located proximal or distal to the treatment element.

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Номер записи: 8
27-09-2012 дата публикации

Subjective significance evaluation tool, brain activity based

Номер: US20120245474A1
Автор: Einat OFEK, Hillel PRATT
Принадлежит: Technion Research and Development Foundation Ltd

A method and system for determining the subjective state of mind of a human subject presented with a test audible or visual stimulus. An an electroencephalogram (EEG) recording unit is connected to the human subject, recording the subject's EEG when presented with one or more test stimuli. The recorded EEG signal is then transformed to a 3-D map in order to visualize the brain areas that were active when presenting the test stimuli. The given 3-D map of the test stimuli is then compared with reference 3-D maps of neutral and subjectively significant stimuli.

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Номер записи: 9
03-01-2013 дата публикации

Contact sensor and sheath exit sensor

Номер: US20130006137A1
Автор: Jeffrey A. Schweitzer, John A. Hauck, Kenneth H. Drew
Принадлежит: St Jude Medical Atrial Fibrillation Division Inc

A system and method is provided that allows for determining the local impedance of one or more electrodes of an electrode catheter. Such local impedance may be utilized to identify the relative position of an electrode catheter to a sheath of a guiding introducer. In another arrangement, local impedance of a catheter electrode can be utilized to calibrate a catheter electrode to provide improved contact sensing.

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Номер записи: 10
07-02-2013 дата публикации

System and method for mapping gastro-intestinal electrical activity

Номер: US20130035576A1
Автор: Andrew John Pullan, Gregory Brian O&#39;grady, Jonathan Christopher Erickson, Leo Koon-Wah Cheng, Peng Du
Принадлежит: Auckland Uniservices Ltd

A gastro-electrical activity mapping system and comprises a catheter insertable through a natural orifice into the gastro-intestinal (GI) tract and comprising an array of electrodes for contacting an interior surface of a section of the GI tract to detect electrical potentials at multiple electrodes, and a signal analysis and mapping system arranged to receive and process electrical signals from multiple electrodes of the array and spatially map GI smooth muscle electrical activity as an activation time map, a velocity map, or an amplitude map, which may be in the form of contour plots and may be mapped on an anatomical computer model of at least the section of the GI tract and may be animated. A GI mapping method and catheter are also claimed.

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Номер записи: 11
28-03-2013 дата публикации

DETECTING AND TREATING NERVOUS SYSTEM DISORDERS

Номер: US20130079616A1
Автор: Asirvatham Samuel J., Bruce Charles J., Friedman Paul A., Holmes David R.
Принадлежит: Mayo Foundation for Medical Education and Research

Some embodiments of a mapping device may be capable of passing through cerebral veins and other cerebrovascular spaces to provide electrophysiological mapping of the brain. These embodiments of the device may also be capable of providing, simultaneously or separately, ablation energy or other treatments to targeted brain tissue. In such circumstances, a user may be enabled to analyze an electrophysiological map of a patient's brain and, at the same time or within a short time period before or after the mapping process, may be enabled to apply ablation energy for treatment of a central nervous system disorder. Such treatment may be accomplished without the use of invasive surgery in which the brain is accessed through an opening in the patient's cranium. 1. A method of using a catheter device to provide intravenous brain mapping from within one or more cerebral veins , comprising:advancing a distal tip portion of a brain mapping catheter device through a patient's vein that extends below the patient's head to a position within one or more cerebral veins proximal to brain tissue within the patient's head, wherein the brain mapping catheter device accesses the one or more cerebral veins without surgical access through an opening in the patient's cranium; andusing one or more electrodes positioned along the distal tip portion of the brain mapping catheter device to detect electrophysiological signals in a portion of the brain tissue while the one or more electrodes remain disposed within the one or more cerebral veins and while a proximal portion of the brain mapping catheter device resides external to the patient.2. The method of claim 1 , further comprising electrically coupling at least one component of the proximal portion of the brain mapping catheter device to an electrophysiological mapping control and display system.3. The method of claim 2 , wherein the brain mapping catheter device comprises a flexible elongated body having an internal conduit through which ...

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Номер записи: 12
11-04-2013 дата публикации

METHODS AND APPARATUSES FOR THE LOCALIZATION AND TREATMENT OF CANCER

Номер: US20130090545A1
Автор: Flynn Edward R.
Принадлежит:

Embodiments of the present invention provide methods of detecting cancer, methods of treating cancer using targeted hyperthermia, methods of treating cancer using targeted chemical agents, methods of treating cancer comprising accurate measurements of the efficacy of treatments. The effect of nanoparticles on magnetic fields can be used to determine the location of a tumor, and a measure of the number of cells in the tumor. This location and measure can be used to guide therapy, and provide information regarding the most effective therapy to be applied. The same nanoparticles can be used to facilitate hyperthermia treatments, and to allow targeted application of chemical therapeutic agents. 1. A method of treating cancer claim 2 , comprising (a) determining the location and number of cells in a tumor according to claim 2 , and (b) applying a therapy to the patient.2. A method for determining the location and number of cells in a tumor comprising introducing magnetic nanoparticles conjugated with biocompatible features that preferentially bind with features common to cells in the tumor claim 2 , subjecting the region of the tumor to a magnetic field claim 2 , measuring the effect of the nanoparticle/feature conjugates on the magnetic field claim 2 , determining the number of cells in the tumor from the magnitude of the effect claim 2 , and determining the location of the tumor by the location of the magnetic moment of the nanoparticle/feature conjugates bound to cancer cells.3. A method as in claim 2 , wherein the effect of the nanoparticle/feature conjugates on the magnetic field is determined by attenuating or removing the applied magnetic field and measuring the decay of the residual magnetic field.4. A method as in claim 1 , wherein step (b) comprises applying hyperthermia to the region of the tumor.5. A method as in claim 4 , wherein applying hyperthermia comprises applying an oscillating magnetic field to the region of the tumor claim 4 , wherein the ...

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Номер записи: 13
11-04-2013 дата публикации

SIMULTANEOUS MULTI-MODALITY INVERSE OPTIMIZATION FOR RADIOTHERAPY TREATMENT PLANNING

Номер: US20130090549A1
Автор: Kaus Michael, Meltsner Michael, Xiong Ying
Принадлежит: KONINKLIJKE PHILIPS ELECTRONICS N.V.

When performing multimodal radiotherapy planning, an optimizer () concurrently optimizes a combined treatment plan that employs an intensity modulated radiotherapy (IMRT) device () and an intensity modulated proton therapy (IMPT) that respectively generate a photon beam and an ion beam for treating a volume of interest () in a patient (). A simulator () iteratively generates multiple variations of a simulation model () according to optimization parameters that are varied by the optimizer () until the simulation model () satisfies user-entered treatment objective criteria () (e.g., maximum dose, does placement, etc.) 1. A system that facilitates optimization of a multimodal radiation therapy plan employing both photon beam and ion beam radiation treatments , including: a display on which is presented to the user information related to one or more radiation treatment plan simulation models;', 'an optimizer that concurrently optimizes dose delivery from a photon therapy device and an ion therapy device in one or more simulation models by iteratively adjusting a plurality of optimization parameters for each of the photon therapy device and the ion therapy device during simulation; and, 'an input graphical user interface (GUI) that includesa simulator that generates the one or more simulation models according to the optimization parameters.2. The system according to claim 1 , wherein the optimizer identifies an optimal simulation model that satisfies predefined radiation treatment objective criteria.3. The system according to claim 1 , further including:a diagnostic scanner that acquires image data of a volume of interest in a patient to be treated using a combined photon and ion radiation treatment; anda reconstruction processor that reconstructs the acquired image data into one or more images that are used by the simulator to identify contours of the patient and the volume of interest to be treated.4. The system according to claim 1 , wherein the ion therapy device ...

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Номер записи: 14
18-04-2013 дата публикации

APPARATUS AND METHOD FOR PREDICTION OF RAPID SYMPTOMATIC BLOOD PRESSURE DECREASE

Номер: US20130096402A1
Автор: Olde Bo, Solem Kristian
Принадлежит: GAMBRO LUNDIA AB

A monitoring arrangement is configured to predict a rapid syruptomatic drop in a subject's blood pressure, e.g. during a medical treatment or when operating aircraft. To this aim, a pulse shape parameter (p) with respect to a peripheral body part () of the subject (P) is repeatedly registered by means of a pulse oximetry instrument () adapted to detect light response variations in blood vessels. A respective pulse magnitude measure is calculated based on each of a number of received pulse shape parameters (p), and a statistical dispersion measure is calculated based on the thus-calculated pulse magnitude measure. It is investigated whether or not the statistical dispersion measure fulfils a decision criterion relative to a reference measure. An output signal (α) is generated if the decision criterion is found to be fulfilled. 1. A monitoring arrangement for predicting rapid symptomatic blood pressure decrease in a subject , the arrangement comprising:a pulse apparatus configured to repeatedly register a pulse shape parameter in a peripheral body part of the subject, wherein the pulse recording apparatus means comprises a pulse oximetry instrument configured to register the pulse shape parameter based on light response variations in at least one blood vessel of the subject, anda control unit configured to receive the pulse shape parameter, the control unit comprising a processing unit configured adapted to:calculate, during a measurement period, a respective pulse magnitude measure based on each of a number of received pulse shape parameters,calculate a statistical dispersion measure from the pulse magnitude measures,investigate whether the statistical dispersion measure fulfils a decision criterion relative to a reference measure, andgenerate an output signal indicating a prediction of said rapid symptomatic blood pressure decrease in the subject.2. The arrangement according to claim 1 , wherein the statistical dispersion measure is any of variance claim 1 , ...

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Номер записи: 15
25-04-2013 дата публикации

Systems and Methods for Visualizing Ablated Tissue

Номер: US20130102862A1
Автор: Kay Matthew W., Mercader Marco A., Sarvazyan Narine
Принадлежит: The George Washington University

Systems and methods for visualizing ablated tissue are disclosed. In some embodiments, a system for imaging tissue includes a catheter having an expandable balloon at a distal end, an illumination device positioned within the balloon for propagating light from an external light source for illuminating a tissue being treated to excite native nicotinamide adenine dinucleotide hydrogen (NADH) in the tissue, and an imaging device positioned within the balloon for detecting fluorescence from the illuminated tissue, the imaging device being configured to communicate detected NADH fluorescence to an external fluorescence camera. 1. A system for imaging tissue comprising:a catheter having an expandable balloon at a distal end;an illumination device positioned within the balloon for propagating light from an external light source for illuminating a tissue being treated to excite native reduced nicotinamide adenine dinucleotide (NADH) in the tissue; andan imaging device positioned within the balloon for detecting fluorescence from the illuminated tissue, the imaging device being configured to communicate detected NADH fluorescence to an external fluorescence camera.2. The system of further comprising an ablation device for ablating the tissue.3. The system of claim 1 , wherein the tissue being treated is heart tissue.4. The system of further comprising a display system connected to the camera for generating an image of the illuminated tissue based on the detected NADH fluorescence.5. The system of claim 4 , wherein in the image tissue that was effected by a treatment is illustrated as having less fluorescence than tissue not affected by the treatment6. The system of further comprising a dichroic mirror and a plurality of filters for conditioning light from the light source and light reflected by the tissue.7. A system for imaging tissue comprising:a catheter system configured to position an illumination device and an imaging device in proximity to a tissue;an ablation device ...

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Номер записи: 16
25-04-2013 дата публикации

MRI-Guided Medical Interventional Systems and Methods

Номер: US20130102883A1
Автор: Jenkins Kimble L., Piferi Peter, Sayler David John
Принадлежит: MRI Interventions, Inc.

An MRI-guided interventional system includes a trajectory guide frame for guiding an interventional device with respect to a patient in an MRI-guided procedure and including a base, a platform, a targeting cannula, and a stabilizer mechanism. The platform is mounted on the base and includes a support table and a moving plate that is translatable relative to the support table and the base along a translational axis. The targeting cannula is mounted on the moving plate for movement therewith and includes an elongate guide bore defining a trajectory axis. The stabilizer mechanism is operable to selectively control movement between the support table and the moving plate to stabilize a position of the targeting cannula with respect to the base. The frame is operable to translate the moving plate along the translational axis relative to the base to position the trajectory axis. The translational axis is transverse to the trajectory axis. 1. An MRI-guided interventional system for use with a body of patient and an interventional device , the system including: a base having a patient access aperture therein, wherein the base is configured to be secured to the body of the patient;', 'a platform mounted on the base and including a support table and a moving plate that is translatable relative to the support table and the base along a translational axis;', 'a targeting cannula mounted on the moving plate for movement therewith relative to the support table and the base, the targeting cannula including an elongate guide bore therethrough, the guide bore defining a trajectory axis and being configured to guide placement of the interventional device in vivo; and', 'a stabilizer mechanism operable to selectively control movement between the support table and the moving plate to stabilize a position of the targeting cannula with respect to the base;', 'wherein the trajectory guide frame is operable to translate the moving plate and thereby the targeting cannula along the ...

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Номер записи: 17
02-05-2013 дата публикации

ELECTROANATOMICAL MAPPING

Номер: US20130109945A1
Автор: Harlev Doron, Stewart Brian
Принадлежит: RHYTHMIA MEDICAL, INC.

This invention relates to the determination and/or representation of physiological information relating to a heart surface. 175-. (canceled)76. A method for providing an electroanatomical representation of a patient's heart , the method comprising:measuring signals at one or more electrodes at multiple positions in the patient's heart cavity over a time period including multiple heart beat cycles, at least some of the signals being in response to electrical activity in the patient's heart cavity;selecting portions of one or more specific signals to process to determine a triggering event based on a second, different signal of the measured signals;applying an algorithm to the selected portions of the one or more specific signals of the measured signals to determine the triggering event in the specific signal;synchronizing, by the computer, the signals measured at the one or more electrodes with one another according to a heart beat cycle based on the triggering event; andgenerating, by the computer, the electroanatomical representation of the patient's heart based on the synchronized measured signals and positions of the catheter electrodes.77. (canceled)78. The method of claim 76 , wherein selecting portions of the specific signal comprises selecting portions of the specific signal to exclude from processing.79. The method of claim 76 , wherein selecting portions of the specific signal comprises selecting portions of the specific signal to include in processing.8084-. (canceled)85. The method of claim 76 , wherein the one or more electrodes comprise one or more electrodes on an intracardiac catheter.86. The method of claim 76 , further comprising:generating, by the computer, annotation information for the measured signals by applying one or more algorithms to the measured signals.87. The method of claim 86 , further comprising conveying at least some of the annotation information to the user.88. The method of claim 76 , further comprising:inserting a catheter ...

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Номер записи: 18
09-05-2013 дата публикации

APPARATUS, SYSTEM, AND METHOD FOR SEIZURE SYMPTOM DETECTION

Номер: US20130116514A1
Автор: Kroner Barbara, Pitruzzello Ann, Shorey Jamie, Strube David C.
Принадлежит: Research Triangle Institute

An apparatus, system, and method are disclosed for detecting seizure symptoms in an individual . A sensor module receives physiological data for an individual from one or more sensors , such as a heart activity sensor. A feature detection module detects a predefined feature in the physiological data. The predefined feature is associated with a seizure or another medical condition. An alert module broadcasts an alert in response to the feature detection module detecting the predefined feature 1. An apparatus to detect seizure symptoms , the apparatus comprising:a sensor module that receives heart activity data for an individual from a heart activity sensor;a feature detection module that detects a predefined feature in the heart activity data, the predefined feature associated with a seizure; andan alert module that broadcasts an alert in response to the feature detection module detecting the predefined feature.2. The apparatus of claim 1 , further comprising a confirmation feature module that detects one or more additional predefined features associated with a seizure in additional data for the individual from one or more additional sensors claim 1 , wherein the sensor module receives the additional data from the one or more additional sensors and wherein the alert module broadcasts the alert in response to the confirmation feature module detecting the one or more additional predefined features.3. The apparatus of claim 2 , wherein the one or more additional sensors include a respiration sensor and the one or more additional predefined features comprise one or more of a predefined increase in an integrated respiration waveform claim 2 , a predefined increase in respiration amplitude claim 2 , a predefined change in respiration rate claim 2 , a breath of at least a predefined duration claim 2 , a breath of at least a predefined amplitude claim 2 , a breath of at least a predefined volume claim 2 , and a predefined change in a period of a respiration interval.4. The ...

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Номер записи: 19
09-05-2013 дата публикации

THREE-DIMENSIONAL THERMAL IMAGING FOR THE DETECTION OF SKIN LESIONS AND OTHER NATURAL AND ABNORMAL CONDITIONS

Номер: US20130116573A1
Автор: Herman Cila
Принадлежит: THE JOHNS HOPKINS UNIVERSITY

A thermal imaging system includes a data processing system and a geometrical scanning system constructed to communicate with the data processing system. The geometrical scanning system is adapted to scan at least a section of a surface of a subject under observation. The thermal imaging system also includes an infrared imaging system constructed to communicate with the data processing system. The infrared imaging system is adapted to image at least a portion of the section of the surface of the subject under observation. The data processing system is configured to receive data from the geometrical scanning system and to construct a surface map of the section of the surface of the subject under observation and to identify geometrical markers on the surface map based on the data from the geometrical scanning system. The data processing system is also configured to receive data from the infrared imaging system and to construct a thermal map of the portion of the section of the surface, to identify thermal markers on the thermal map based on the data from the infrared imaging system, and to register the thermal map to the surface map based on a correspondence between at least some of the geometrical and thermal markers. The data processor is configured to correct temperatures of the thermal map based on the surface map subsequent to the registering. 1. A thermal imaging system , comprising:a data processing system;a geometrical scanning system constructed to communicate with said data processing system, said geometrical scanning system being adapted to scan at least a section of a surface of a subject under observation; andan infrared imaging system constructed to communicate with said data processing system, said infrared imaging system being adapted to image at least a portion of said section of said surface,wherein said data processing system is configured to receive data from said geometrical scanning system and to construct a surface map of said section of said ...

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Номер записи: 20
23-05-2013 дата публикации

PLANNING SYSTEM FOR TARGETING TISSUE STRUCTURES WITH ULTRASOUND

Номер: US20130131495A1
Автор: DEFFIEUX Thomas, Konofagou Elisa E.
Принадлежит: The Trustees of Columbia University in the City of New York

The disclosed subject matter provides systems and methods for targeting tissue structures and applying ultrasound thereto. A method according to the disclosed subject matter for targeting a tissue structure using corresponding tissue structure image data includes inputting the tissue structure image data into a targeting simulator, determining acoustic properties of the tissue structure from the corresponding tissue structure image data, and utilizing the determined acoustic properties to align a simulated transducer with the tissue structure such that the tissue structure is targeted. The method can further include acquiring the tissue structure image data, aligning the image data with an atlas of a body structure encompassing the tissue structure and/or selecting parameters of the simulated transducer such that a focal region of an ultrasound wave generated by the simulated transducer targets the tissue structure. 1. A method for targeting a tissue structure using corresponding tissue structure image data , comprising:receiving the tissue structure image data into a targeting simulator;determining one or more acoustic properties of the tissue structure from the corresponding tissue structure image data; andutilizing the determined one or more acoustic properties to align a simulated transducer with the tissue structure such that the tissue structure is targeted.2. The method of claim 1 , further comprising acquiring the tissue structure image data.3. The method of claim 2 , wherein the acquiring comprises acquiring a CT scan of at least the tissue structure.4. The method of claim 2 , wherein the acquiring comprises acquiring an MRI of at least the tissue structure.5. The method of claim 1 , further comprising aligning the tissue structure image data with an atlas of a body structure encompassing the tissue structure.6. The method of claim 1 , further comprising selecting parameters of the simulated transducer such that a focal region of an ultrasound wave ...

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Номер записи: 21
23-05-2013 дата публикации

APNEA TYPE DETERMINING APPARATUS AND METHOD

Номер: US20130131522A1
Автор: Patangay Abhilash, Pu Yachuan
Принадлежит: Cardiac Pacemakers, Inc.

An apnea classification system provides for apnea monitoring and differentiation based on several sleep apnea related parameters for diagnostic and therapeutic purposes. Monitoring of such sleep apnea related parameters allows the apnea classification system to differentiate among the different types of apnea and hypopnea and to identify an occurrence of periodic respiration. This information may then be used to determine the best method of therapy, or adjust current therapy parameters to more effectively treat a subject. 1. A system comprising:a respiration-based sensor configured to receive information indicative of inhalation or exhalation;a non-respiration-based sensor configured to receive information other than information indicative of inhalation or exhalation; andan apnea detection module, coupled to the respiration-based and non-respiration-based sensors, configured to recognize an apnea using information from both the respiration-based and non-respiration-based sensors.2. The system of claim 1 , wherein the respiration-based sensor is configured to receive cyclic information indicative of inhalation or exhalation claim 1 , and wherein the apnea detection module is configured to recognize the apnea using the cyclic information.3. The system of claim 2 , wherein the non-respiration-based sensor is configured to receive information other than cyclic information claim 2 , and wherein the apnea detection module is configured to recognize the apnea using the information other than the cyclic information.4. The system of claim 1 , wherein the respiration-based sensor includes an impedance sensor configured to detect impedance information that is indicative of inhalation or exhalation.5. The system of claim 1 , wherein the respiration-based sensor includes a blood pressure sensor configured to detect blood pressure information that is indicative of inhalation or exhalation.6. The system of claim 1 , wherein the non-respiration-based sensor includes a blood ...

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Номер записи: 22
13-06-2013 дата публикации

DEVICE FOR SENSING A TARGET CHEMICAL AND METHOD OF ITS MAKING

Номер: US20130150689A1
Автор: SHAW-KLEIN Lori J.
Принадлежит: MICROPEN TECHNOLOGIES CORPORATION

The present invention relates to a device for sensing a target chemical. The device includes a flexible, non-planar substrate; a printed, solid-state sensing element comprising a chemical sensing material which produces an electrical signal upon interaction with the target chemical; a first printed electrode comprising a first conductive composition; and a second electrode comprising a second conductive composition. The first and second electrodes are electrically isolated from one another, and one or both of the first and second electrodes is in electrical contact with said sensing element. The first and second electrodes and the sensing element collectively form an electrochemical sensor which is coupled to the flexible, non-planar substrate. Medical devices comprising the device of the present invention and methods of making a device for sensing a target chemical are also disclosed. 1. A device for sensing a target chemical comprising:a flexible, non-planar substrate;a printed, solid-state sensing element comprising a chemical sensing material which produces an electrical signal upon interaction with the target chemical;a first printed electrode comprising a first conductive composition; anda second electrode comprising a second conductive composition, wherein said first and second electrodes are electrically isolated from one another, and one or both of the first and second electrodes is in electrical contact with said sensing element, wherein said first and second electrodes and said sensing element collectively form an electrochemical sensor, which is coupled to said flexible, non-planar substrate.2. The device according to claim 1 , wherein the first printed electrode is in electrical contact with said sensing element.3. The device according to claim 1 , wherein both the first and second electrodes are in electrical contact with said sensing element.4. The device according to claim 1 , wherein the second electrode is printed onto the substrate.5. The device ...

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Номер записи: 23
13-06-2013 дата публикации

SURGICAL TISSUE MONITORING SYSTEM

Номер: US20130150694A1
Автор: Beetel Robert, Viola Frank
Принадлежит: COVIDIEN LP

A tissue monitoring system includes an introducer having an inflatable section and a plurality of electrodes disposed thereon. The electrodes are alternatively connected to an electrode contact system which includes at least one signal line and at least one measurement line for taking readings about a circumferential segment of tissue encompassed by the electrodes. 1. A method of monitoring tissue comprising:placing an introducer having an inflatable section and a plurality of electrodes disposed about the inflatable section adjacent to a section of tissue;distending the first inflatable section of the introducer;imposing an electrical signal on the tissue using a subset of the plurality of electrodes selected for an electrode contact system;measuring a resulting potential with the subset of the plurality of electrodes of the electrode contact system; andshifting the electrode contact system to alternate placement of the electrode contact system within the tissue.2. The method of claim 1 , wherein the step of shifting the electrode contact system includes electronically shifting each contact of the electrode contact system to encompass a different subset of the plurality of electrodes.3. The method of claim 2 , wherein electronically shifting each contact includes shifting each contact to an adjacent electrode on the inflatable section of the introducer.4. The method of claim 1 , wherein the introducer further includes a shaft extending through the introducer claim 1 , and wherein the step of shifting the electrode contact system includes rotating the shaft to shift the electrode contact system clockwise or counterclockwise around a circumferential segment of the tissue.5. The method of claim 1 , further comprising repeating the step of shifting the electrode contact system until an entire circumference of the tissue is characterized.6. The method of claim 1 , wherein the step of imposing an electrical signal includes attaching two electrodes of the subset of the ...

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Номер записи: 24
13-06-2013 дата публикации

INTUITIVE PRESENTATION OF VENTILATION EFFECTIVENESS

Номер: US20130150734A1
Автор: Brewer Lara, Goerges Matthias, Orr Joseph Allen, Westenskow Dwayne Ronald
Принадлежит: KONINKLIJKE PHILIPS ELECTRONICS N.V.

Ventilation information may be presented. Output signals may be received that convey information related to one or more breathing parameters of a subject receiving assisted or controlled mechanical ventilation. Based at least in part on the received output signals, volumetric components of a tidal volume of the subject may be determined. The volumetric components may include an alveolar dead space, an effective alveolar tidal volume, and/or other volumetric components. The alveolar dead space is the volume of inspired gas that occupies alveoli but does not take part in oxygen exchange in the lungs of the subject. The effective alveolar tidal volume is the volume of inspired gas that takes part in oxygen exchange in the lungs of the subject. A visual representation that textually or graphically represents the tidal volume, and/or textually or graphically represents the volumetric components separately from each other may be presented via a user interface. 1. A method for presenting ventilation information , the method comprising:receiving output signals conveying information related to one or more breathing parameters of a subject being mechanically ventilated;determining, based on the received output signals, volumetric components of a tidal volume of the subject, the volumetric components including (i) an alveolar dead space, and (ii) an effective alveolar tidal volume, the alveolar dead space being the volume of inspired gas that occupies alveoli but does not take part in oxygen exchange in the lungs of the subject, and the effective alveolar tidal volume being the volume of inspired gas that takes part in oxygen exchange in the lungs of the subject; andpresenting, via a user interface, a visual representation least a portion of a human respiratory system (i) that provides updated ventilation information in an ongoing manner and (ii) that textually or graphically represents the tidal volume and the volumetric components in a manner which makes analysis of (ii)(a) ...

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Номер записи: 25
20-06-2013 дата публикации

INTEGRATED, HAND-HELD APPARATUS AND ASSOCIATED METHOD FOR ACQUIRING DIAGNOSTIC AND PROGNOSTIC INFORMATION FROM A PATIENT AT THE BEDSIDE OR AT SOME OTHER PATIENT LOCATION

Номер: US20130158363A1
Автор: Zoghbi William
Принадлежит:

An integrated, hand-held apparatus for acquiring diagnostic and prognostic information from a patient at the bedside or at some other patient location, the apparatus including a wand with a microphone for acquiring sound information from the patient and an ultrasound emitter/receiver for acquiring image data from the patient, a base unit including a speaker for presenting sound information to a user and a display for presenting image information to a user, and transferring the sound information acquired by the microphone and the image information acquired by the ultrasound emitter/receiver from the wand to the base unit. 1. An integrated , hand-held apparatus for acquiring diagnostic and prognostic information from a patient at the bedside or at some other patient location , the apparatus comprising: a microphone for acquiring sound information from the patient; and', 'an ultrasound emitter/receiver for acquiring image data from the patient; and, 'a wand comprising a speaker for presenting sound information to a user; and', 'a display for presenting image information to a user; and, 'a base unit comprisingtransferring means for transferring the sound information acquired by the microphone, and the image information acquired by the ultrasound emitter/receiver, from the wand to the base unit.2. Apparatus according to wherein the wand is releasably secured to the base unit.3. Apparatus according to wherein the base unit is configured to present sound information as image information on the display.4. Apparatus according to wherein the transferring means are configured to wirelessly transfer the sound information acquired by the microphone claim 1 , and the image information acquired by the ultrasound emitter/receiver claim 1 , from the wand to the base unit.5. Apparatus according to wherein the base unit comprises a base unit wireless transceiver claim 4 , the wand comprises a wand wireless transceiver claim 4 , and the wand wireless transceiver is configured to ...

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Номер записи: 26
20-06-2013 дата публикации

MEDICAL DEVICE WITH SLOTTED MEMORY METAL TUBE

Номер: US20130158414A1
Автор: BESSELINK PETRUS A., SACHDEVA ROHIT C. L.
Принадлежит: EVM SYSTEMS LLC

A series of medical instruments can be made with the use of shape memory tube with a transformation temperature that is above or below ambient temperature. In the first case, the material behaves with the shape memory effect and in the second case the behavior is superelastic. The wall of the tube has been provided with a plurality of slots in specific places, often near or at the distal end of the instrument, and in specific arrangements which allow local variations in diameter, shape, and/or length. These variations can either be caused by the memory effect during temperature change or by superelastic behavior during change of the mechanical influences on the memory metal by the surrounding material. 1. A medical instrument comprising:at least one memory metal tube programmed for memory effect or superelasticity and having in at least one section thereof a plurality of slots such that the slotted section is capable of expansion and contraction, said memory metal tube having an expandable section that is substantially filled by an elastically deformable polymer, which upon expansion in a tubular cavity plugs the cavity; anda delivery tube that surrounds at least the slotted section of the memory metal tube during delivery and which is partially removed from surrounding the slotted section of the memory metal tube by a relative longitudinal movement between the respective tubes.2. The instrument of being a retrieval basket for retrieving particles to be removed from the human body.3. The instrument of being a dilator to enlarge the diameter of collapsed or obstructed ducts claim 1 , veins claim 1 , arteries or other cavities in the human body.4. The instrument of being a reaming tool to cut parts off the wall of a cavity by rotational movement around the longitudinal axis of the instrument.5. The instrument of being an expansion tool that is expandable at a distal end to enlarge a body cavity.6. The instrument of wherein the slots in the memory metal tube extend to ...

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Номер записи: 27
20-06-2013 дата публикации

PRESSURE SENSING SYSTEM AND METHOD

Номер: US20130158426A1
Автор: HOLM William, JUTO Fredrik, JUTO Jan-Erik
Принадлежит: CHORDATE MEDICAL AG

A device for detecting rhinitis in a human subject includes an inflatable member that, in a first state, is configured to be introducible into the nasal cavity of the human subject; an expansion member configured to expand the inflatable member to an expanded, second state within the nasal cavity such that the inflatable member abuts against the tissue of the nasal cavity, and a pressure sensing member configured to measure a pressure exerted on the inflatable member by the tissue of the nasal cavity. A system for detecting rhinitis and methods for analyzing tissue response pressure, detecting rhinitis, predicting the efficacy of a planned rhinitis treatment and evaluating the efficacy of a previous rhinitis treatment are provided. 1. A method for detecting rhinitis , comprising:introducing an inflatable member into a nasal cavity of a human subject;expanding the inflatable member within the nasal cavity such that the inflatable member abuts against a tissue of the nasal cavity;measuring a pressure exerted on the inflatable member by the tissue of the nasal cavity over a period of time to create a measured pressure curve; andanalyzing the measured pressure curve to detect rhinitis.2. A method for evaluating the efficacy of a previously performed rhinitis treatment , comprising:introducing an inflatable member into a nasal cavity of a human subject;expanding the inflatable member within the nasal cavity such that the inflatable member abuts against a tissue of the nasal cavity;measuring a pressure exerted on the inflatable member by the tissue of the nasal cavity over a period of time to create a measured pressure curve; andanalyzing the measured pressure curve to evaluate the efficacy of the previous rhinitis treatment.3. A method for predicting the efficacy of a rhinitis treatment , comprising:introducing an inflatable member into a nasal cavity of a human subject;expanding the inflatable member within the nasal cavity such that the inflatable member abuts against ...

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Номер записи: 28
20-06-2013 дата публикации

Device and method for measuring pressure exerted on a surface

Номер: US20130158436A1
Автор: Craig S. Niederberger, Ervin Kocjancic
Принадлежит: University of Illinois

Provided are methods and devices for measuring pressure exerted against a surface. In an aspect, the surface corresponds to the urethra and the device measures the pressure exerted against the urethra. Methods include treatment of a patient suffering urinary stress incontinence. A pressure sensor system is used to determine, pre-surgically, the minimum pressure required to alleviate incontinence. During surgery, the pressure sensor system is employed to ensure the surgical intervention provides a corresponding minimum pressure that was clinically identified. In this manner, the surgical intervention is precisely monitored and measured to insure the appropriate pressure is exerted on the urethra to alleviate stress incontinence, thereby improving surgical outcome and decreasing post-operative complications.

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Номер записи: 29
27-06-2013 дата публикации

Systems and methods for making and using medical ablation systems having mapping catheters with improved anchoring ability

Номер: US20130165759A1
Автор: David McGee, Isaac Kim, Josef V. Koblish
Принадлежит: Boston Scientific Scimed Inc

A mapping catheter includes an elongated body for inserting into patient vasculature. A distal end of the elongated body includes a distal portion that includes a plurality of electrodes, a proximal portion disposed proximal to the distal portion, and a reduced-dimension portion disposed between the proximal and distal portions. The distal end is formed, at least in part, from a memory shape material that bends into a preformed shape upon release from a confined space. The preformed shape includes a first loop formed, at least in part, by the distal portion. The first loop is transverse to a longitudinal axis of the proximal portion. The reduced-dimension portion is configured and arranged to bend such that the reduced-dimension section advances distally through the first loop when the first loop is held in a fixed position and a force is applied distally along the longitudinal axis of the proximal portion.

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Номер записи: 30
04-07-2013 дата публикации

IDENTIFYING AREAS OF THE BRAIN BY EXAMINING THE NEURONAL SIGNALS

Номер: US20130172716A1
Автор: Cameron Tracy L., Lozano Andres M.
Принадлежит:

The present invention relates to a method of identifying a region of the brain by measuring neuronal firing and/or local field potentials by recording discharges from at least one implanted electrode and analyzing the recording of the discharges within the beta frequency band range to determine an area of beta oscillatory activity. Once the region of the brain is identified, this region may be stimulated to disrupt the beta oscillatory activity thereby treating a movement disorder. 1. A method of identifying a region of the brain comprising the steps of:measuring neuronal firing and/or local field potentials by recording discharges from at least one implanted electrode; andanalyzing the recording of the discharges within the beta frequency band range to determine an area of beta oscillatory activity thereby identifying the region of the brain.2. The method of claim 1 , wherein the electrode is implanted in the cortex claim 1 , subthalamic nucleus claim 1 , basal ganglia claim 1 , or globus pallidus.3. The method of claim 1 , wherein the discharges of neuronal firing and local field potentials are synchronized.4. The method of further comprising the step of stimulating the identified brain region to disrupt the discharges thereby treating a disease.5. The method of claim 4 , wherein the disease is a movement disorder.6. The method of claim 5 , wherein the movement disorder is Parkinson's disease.7. A method of improving at least one symptom in an individual suspected of having a movement disorder claim 5 , comprising the steps of:measuring neuronal firing and/or local field potentials by recording discharges from at least one electrode implanted in the subthalamic nucleus;analyzing the recording of the discharges within the beta frequency band range to determine an area of synchronized beta oscillatory activity; andstimulating the area to disrupt the beta oscillatory activity, thereby improving at least one symptom in the individual.8. The method of claim 7 , wherein ...

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Номер записи: 31
04-07-2013 дата публикации

METHOD AND APPARATUS FOR MONITORING THE RESPIRATION ACTIVITY OF A SUBJECT

Номер: US20130172770A1
Автор: Muehlsteff Jens
Принадлежит: KONINKLIJKE PHILIPS ELECTRONICS N.V.

The invention relates to a method for monitoring the respiration activity of a subject, comprising the acquisition of a sensor signal of at least one Doppler-Radar sensor representing the respiration activity of a subject, the transformation of the sensor signal into a transformation signal being a series according to Formula (I) where ais a set of predetermined constant coefficients specific for one individual subject, and processing the transformation signal S(t). The transformation signal can be analysed with basic signal processing techniques that are applied in the field of inductive plethysmography. The invention is further related to a corresponding monitoring system. 2. The method according to claim 1 , characterized in that the set of coefficients ais taken from a look-up table.3. The method according to claim 2 , characterized in that the look-up table contains a plurality of different sets of coefficients a.4. The method according to claim 3 , characterized in that the subject is identified claim 3 , and one corresponding set of coefficients ais chosen from the plurality of sets of coefficients aaccording to the result of the identification.6. The method according to claim 1 , characterized in that D(t) is the sum of the sensor signals D(t) claim 1 , i=1 to n from n sensors.7. The method according to claim 1 , characterized in that a plurality of sensor signals D(t) claim 1 , i=1 to n is acquired from a plurality of n sensors claim 1 ,{'sub': 'k', 'and one set of coefficients ais determined for each one of these n sensors.'}1018. System according to claim 9 , characterized by a plurality of Doppler-Radar sensors () disposed at different positions within a measurement range.1120. System according to claim 10 , characterized in that said sensor transformation unit () is provided for transforming a sensor signal D(t) of each sensor i into a transformation signal S(t) and to summarize the resulting transformation signals S(t) to a summarized transformation ...

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Номер записи: 32
04-07-2013 дата публикации

Determining apparatus and determining method

Номер: US20130172863A1
Автор: Arisa Ito, Koshi Tamamura, Shiho Hakomori, Takashi Yamaguchi, Tsunenori Arai
Принадлежит: KEIO UNIVERSITY, Sony Corp

A photodynamic therapy apparatus as a determining apparatus is the photodynamic therapy apparatus for irradiating a tissue having absorbed photo-sensitive pharmaceutical, the photo-sensitive pharmaceutical absorbing an excitation light and emitting fluorescence, or a tissue absorbing the excitation light and emitting fluorescence, with the excitation light emitted from a tip portion of a laser catheter, including a connector, a light source, and a light detection unit. The laser catheter is capable of being attached/detached to/from the connector. The light source outputs the excitation light to the laser catheter via the connector. The light detection unit detects intensity or a spectrum of the fluorescence, the fluorescence being entered from the laser catheter via the connector, to determine whether the tip portion of the laser catheter contacts the tissue or not.

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Номер записи: 33
11-07-2013 дата публикации

Methods and Apparatus for Regulating Blood Pressure

Номер: US20130178750A1
Автор: Kinghorn Curtis, Sheehan David M.
Принадлежит: VOLCANO CORPORATION

A blood pressure control apparatus, system, and methods of modifying intravascular blood flow of a patient is disclosed. In one aspect, the blood pressure control apparatus comprises an intravascular flow-modifying device including an expandable, hollow, stent-like support member configured for implantation within the vasculature, which includes an upstream sensor, a downstream sensor, and a flow restrictor. The flow restrictor is configured to partially occlude a vessel lumen and thereby artificially create back pressure upstream of the device, which causes dilation of the vessel wall and activation of the baroreceptors upstream of the device. Activation of the baroreceptors may depress the activity of the sympathetic nervous system, thereby contributing to a decrease in systemic blood pressure. The flow restrictor is also configured to partially occlude the renal vein lumen, thereby artificially increasing renal perfusion and depressing the baroreceptor-mediated sympathetic and neurohormonal efforts to raise blood pressure. 1. A method of treating hypertension , comprising:implanting a flow restricting device in the vasculature of a patient;sensing blood pressure;actuating the flow restricting device in response to the sensed blood pressure to modify the flow of blood through the flow restrictor; andsensing the blood pressure after said actuating to determine the effect of the modification of the blood flow.2. The method of claim 1 , wherein the flow restricting device includes a sensor and said sensing includes activating the onboard sensor.3. The method of claim 1 , wherein the flow restricting device includes an electrical actuator and the step of actuating includes sending an electrical signal to the actuator.4. The method of claim 2 , wherein the flow restricting device includes a power supply claim 2 , and the sensing step includes powering the sensor.5. The method of claim 1 , wherein the flow restricting device includes a power harvesting mechanism claim 1 ...

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Номер записи: 34
11-07-2013 дата публикации

MULTIPLE ORAL AND NASAL SURGICAL PROCEDURES METHOD AND KIT

Номер: US20130178763A1
Автор: AL-TERKI ABDULMOHSEN E.A.H.
Принадлежит:

The method of performing multiple oral and nasal surgical procedures in the head and neck region provides a systematic procedure for the performance of multiple operations for correcting various ear, nose, and throat conditions that cause snoring and obstructive sleep apnea (OSA) in the patient. The method allows the surgeon to perform multiple operating procedures in the nose, mouth, and/or throat in a single operating session, due to the use of hemostatic sheet and gel treatments in lieu of suturing and post-operative nasal hemostatic packs that preclude nasal breathing. The various surgical implement kits allow the surgeon to select the appropriate kit according to the procedure(s) to be performed. The procedure(s) is/are selected in accordance with a specific customized treatment plan that is developed by the surgeon for the individual patient, which other surgeons involved in snoring or OSA surgery can comprehend. 1. A method for developing a system for the evaluation of the severity of an obstructive sleep apnea condition , comprising the steps of:(a) assigning a first letter S to represent the sinonasal area of a person having obstructive sleep apnea;(b) assigning a first letter T to represent the tonsils of the person;(c) assigning the letter A to represent the adenoids of the person;(d) assigning a second letter T to represent the tongue of the person;(e) assigning a second letter S to represent the soft palate of the person;(f) arranging the letters of the steps (a) through (e) in order to arrive at the term STATS;(g) evaluating the sinonasal area of the person;(h) assigning a quantitative value to the sinonasal area of the person, in accordance with the results of the evaluation of step (f);(i) placing the quantitative value of the sinonasal area immediately following the first letter S in the series;(j) evaluating the tonsils of the person;(k) assigning a quantitative value to the tonsil area of the person, in accordance with the results of the ...

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Номер записи: 35
18-07-2013 дата публикации

WEANING FROM VENTILATION USING CAPNOGRAPHY

Номер: US20130180526A1
Автор: Davidpur Keren, Einav Sharon, Ronen Michal
Принадлежит: Oridion Medical 1987 Ltd.

There is provided herein a method for monitoring weaning of a subject from a respiratory ventilator, the method comprising characterizing distinct patterns in a series of CO2 waveforms obtained from expired breath of a subject undergoing respiratory ventilation weaning, wherein said distinct patterns are indicative to the effectiveness of a weaning process and wherein said distinct patterns are selected from a group consisting of “sigh events”, “spike events” and “pools”; and providing an indication relating to the effectiveness of the weaning process. 1. A method for monitoring weaning of a subject from a respiratory ventilator , the method comprising:{'sub': '2', 'characterizing distinct patterns in a series of COwaveforms obtained from expired breath of a subject undergoing respiratory ventilation weaning, wherein said distinct patterns are indicative to the effectiveness of a weaning process and wherein said distinct patterns are selected from a group consisting of “sigh events”, “spike events” and “pools”; and'}providing an indication relating to the effectiveness of the weaning process.2. The method of claim 1 , further comprising providing a signal to a ventilator at least partially based on the characterized distinct patterns in the series of COwaveforms and thus inducing a change in one or more parameters of the ventilator.3. The method of claim 2 , wherein said change in one or more parameters of the ventilator comprises a change in the level of support to the ventilation claim 2 , allowing the patient to rest from weaning attempts claim 2 , changing a mode/program of weaning or any combination thereof.4. The method of claim 2 , wherein providing a signal to the ventilator is further based on one or more additional parameters selected from the group consisting of: age of the subject claim 2 , medical condition of the subject claim 2 , medical history of the subject and medications administered to the subject.5. The method of claim 2 , wherein providing a ...

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Номер записи: 36
18-07-2013 дата публикации

SINGLE INJECTION METHODS FOR OBTAINING CONDUCTANCE MEASUREMENTS WITHIN LUMINAL ORGANS USING IMPEDANCE DEVICES

Номер: US20130184553A1
Автор: Browder John, Kassab Ghassan S., Svendsen Mark
Принадлежит:

Single injection methods for obtaining conductance measurements within luminal organs using impedance devices. In at least one method embodiment, the method is performed by introducing at least part of an impedance device into a mammalian luminal organ, the impedance device comprising an elongated body and a detector positioned along the elongated body, obtaining conductance measurements indicative of a fluid native to the mammalian luminal organ and indicative of a fluid injection while the detector is present within and outside of the lumen of the outer sheath, and calculating a size parameter of the mammalian luminal organ based in part upon some of the obtained conductance measurements. 1. A method for obtaining one or more conductance measurements using an impedance device , the method comprising the steps of:introducing at least part of an impedance device into a mammalian luminal organ, the impedance device comprising an elongated body and a detector positioned along the elongated body;obtaining a first conductance measurement using the detector while the detector is surrounded by an outer sheath surrounding at least part of the impedance device, the first conductance measurement indicative of a fluid native to the mammalian luminal organ present within a lumen of the outer sheath;obtaining a second conductance measurement using the detector while the detector is surrounded by the outer sheath, the second conductance measurement indicative of a first injection of a first solution of a first compound through the lumen of the outer sheath;moving the impedance device and/or the outer sheath relative to one another so that the outer sheath no longer surrounds the detector;obtaining a third conductance measurement using the detector, the third conductance measurement indicative of the fluid native to the mammalian luminal organ;obtaining a fourth conductance measurement using the detector, the fourth conductance measurement indicative of a second injection of the ...

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Номер записи: 37
18-07-2013 дата публикации

SYSTEMS AND METHODS FOR FILTERING ECG ARTIFACTS

Номер: US20130184600A1
Автор: FREEMAN Gary A., GEHEB Frederick J., Tan Qing
Принадлежит: ZOLL MEDICAL CORPORATION

Systems and methods of processing raw electrocardiogram (ECG) waveform data of a patient into estimated real-time ECG waveform data. The method includes sensing at least one physical non-cardiac influence on the raw ECG waveform data, constructing a time domain computer model of the at least one physical, non-cardiac influence on the raw ECG waveform data, and adaptively filtering the raw ECG waveform data in the time domain using the constructed time domain computer model of the at least one physical non-cardiac influence on the raw ECG waveform data to form the estimated real-time ECG waveform data. The system can include an ECG device for collecting raw ECG waveform data, at least two ECG electrodes positioned on the patient and electrically coupled to the ECG device, and a processor coupled to the ECG device and configured to compute a time domain model of an artifact created by chest compressions. 1. A method of processing raw electrocardiogram (ECG) waveform data of a patient into estimated real-time ECG waveform data , the method comprising:sensing at least one physical non-cardiac influence on the raw ECG waveform data;constructing a time domain computer model of the at least one physical, non-cardiac influence on the raw ECG waveform data; andadaptively filtering the raw ECG waveform data in the time domain using the constructed time domain computer model of the at least one physical non-cardiac influence on the raw ECG waveform data to form the estimated real-time ECG waveform data.2. The method of claim 1 , wherein the at least one physical non-cardiac influence on the raw ECG waveform is caused by repeated chest compressions claim 1 , and wherein constructing a time domain computer model includes collecting several cycles of chest compressions and calculating a chest compression artifact.3. The method of claim 1 , wherein adaptively filtering the raw ECG waveform data includes subtracting the constructed time domain computer model of the at least one ...

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Номер записи: 38
01-08-2013 дата публикации

SYSTEMS AND METHODS USING BIOMARKER PANEL DATA

Номер: US20130196870A1
Автор: Meyer Timothy E., Seth Milan, Spinale Francis G., Stolen Craig M., Wold Nicholas David
Принадлежит:

Embodiments of the disclosure are related to systems and methods for utilizing biomarker panel data and related medical devices and methods, amongst other things. An embodiment can include a method of screening patients. The method can include quantifying levels of one or more of a panel of biomarkers in a biological sample of a patient. The method can further include analyzing the quantified levels. In some embodiments, the panel of biomarkers includes at least two selected from the group consisting of CRP, SGP-130, sIL-2R, sTNFR-II, IFNg, BNP, sST2, MMP-2, MMP-9, TIMP-1, TIMP-2, TIMP-4. In an embodiment, the disclosure can include a method of diagnosing a patient. The method can include quantifying levels of one or more of a panel of biomarkers in a biological sample of a patient. The method can further include diagnosing the patient based at least in part on the quantified levels. In some embodiments, the panel of biomarkers includes at least two selected from the group consisting of CRP, SGP-130, sIL-2R, sTNFR-II, IFNg, BNP, sST2, MMP-2, MMP-9, TIMP-1, TIMP-2, TIMP-4. Other embodiments are also included herein. 1. A method of screening patients:quantifying levels of one or more of a panel of biomarkers in a biological sample of a patient; andanalyzing the quantified levels;wherein the panel of biomarkers includes at least two selected from the group consisting of CRP, SGP-130, sIL-2R, sTNFR-II, IFNg, BNP, sST2, MMP-2, MMP-9, TIMP-1, TIMP-2, TIMP-4.2. The method of claim 1 , wherein analyzing the quantified levels includes determining whether the patient is at risk for experiencing heart failure decompensation.3. The method of claim 1 , wherein analyzing the quantified levels includes determining whether the patient is at risk for rapid decline in clinical symptoms of heart failure.4. The method of claim 1 , wherein analyzing the quantified levels includes determining whether the patient is at risk for adverse ventricular remodeling.5. The method of claim 1 , ...

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Номер записи: 39
01-08-2013 дата публикации

NEURAL MONITORING METHODS AND SYSTEMS FOR TREATING UPPER AIRWAY DISORDERS

Номер: US20130197321A1
Автор: Wilson Willard
Принадлежит: NEUROSTREAM TECHNOLOGIES G.P.

Methods and systems for monitoring, preventing and/or treating upper airway disorders such as apnea, dysphagia, reflux and/or snoring are described. The methods and systems monitor the upper airway disorders by processing one or more neural signals obtained from one or more upper airway afferents. Upper airway disorders are prevented and/or treated by delivering one or more stimulations to one or more reflex-related afferents, efferents, muscles, and sensory receptors to manipulate the threshold and/or trigger an upper airway reflex including, but not limited to a swallow reflex and/or a negative-pressure reflex. 1. A method for monitoring a condition in a subject , the method comprising:obtaining one or more neural signals from one or more upper airway afferents of the subject;processing each of the one or more neural signals to obtain at least one neural activity profile, each neural activity profile characterized by at least one of: a neural signal timing, a neural signal amplitude, a neural signal phase, a neural signal position, a neural signal conduction velocity, and any combination thereof;comparing each of the at least one neural activity profiles to one or more activity criteria to associate each neural activity profile with an associated activity type chosen from a respiratory activity type, a deglutition activity type, a vibration activity type, a reflux activity type, and any combination thereof; a respiratory state comprising respiratory timing, respiratory amplitude, respiratory phase, respiratory location, and any combination thereof;', 'a deglutition state comprising solid contact, fluid contact, contact velocity, contact timing, contact amplitude, contact pressure, contact texture, contact temperature, a presence of a unswallowed bolus, and any combination thereof;', 'a vibration state comprising vibration timing, vibration amplitude, vibration phase, vibration location, vibration pattern, and any combination thereof; and', 'a reflux state ...

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Номер записи: 40
01-08-2013 дата публикации

Potential Artery-to-Vein Disease State Detection

Номер: US20130197340A1
Автор: Redd Christian, Sanders Joan E.
Принадлежит: University of Washington through its Center for Commercialization

A method/apparatus/system for detection of a potential disease state is disclosed. A pair of electrodes is attached to a limb and the electrodes are energized. The energizing of the electrodes creates a first signal in the form of current data. If the first signal is consistent with a potential disease state, including a potential artery-to-vein disease state, an indication of the potential disease state is provided. 1. A method for identifying a potential vascular disease state of a limb of a patient , the limb comprising an outer surface and a first region , the method comprising:placing a plurality of electrodes on the limb, including a first electrode on the outer surface of the limb adjacent the first region;energizing at least some of the electrodes while the limb of the patient is in a first arterial to vein transport state so as to generate a first signal with the first electrode;determining that the first signal is consistent with the potential vascular disease state of the limb in response to the first signal; andproviding an indication of the potential vascular disease state of the limb.2. The method recited in claim 1 , the first region of the limb including tissue with associated veins and arteries claim 1 , further comprising:placing a second electrode pair on the outer surface of the limb adjacent a second region of the limb, the second region including tissue with associated veins and arteries; andgenerate a second signal with the second electrode; anddetermining the first signal and the second signal correspond to the potential vascular disease state, the potential vascular disease state comprising an artery-to-vein disease state.3. The method recited in claim 2 , further comprising:localizing the potential vascular disease state in the first region in response to the first and second signals; andselectively directing therapy to the first region so as to mitigate the potential vascular disease state.4. The method of claim 3 , the tissue of the first ...

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Номер записи: 41
01-08-2013 дата публикации

Detecting and treatment of sleep apnea

Номер: US20130197376A1
Автор: Alt Eckhard, Gollasch Maik
Принадлежит:

A device is presented for evaluating whether an episode of sleep apnea is occurring in a patient suffering from chronic sleep apnea disorder, for delivery of appropriate therapy. The device includes circuitry adapted to respond to a cardiac signal generated by the heart. Switching circuitry diverts passage of the heart signal through both a high impedance path and a substantially lower impedance path, and a differential amplifier processes the resulting signal pairs to ascertain the difference in magnitude between the two signals of each pair. An analyzer thereof determines changes in the patient's ventilation, from which inordinately reduced patient ventilation is detected to assess possible occurrence of an episode of sleep apnea. If the analyzer denotes change of ventilation between otherwise regular respiratory cycles, an actual episode of sleep apnea is indicated. A stimulus generator responds to such indication to generate an appropriate electrical therapy for delivery to a preselected location in the patient's body to induce ventilation so as to terminate the apnea episode. 1. A device for detecting sleep apnea in a patient , comprising:circuitry adapted to respond to the EKG signal generated by the patient's heart for diverting the EKG signal in separate paths of high input impedance and of considerably lower impedance to produce two different signals, and a differential amplifier of said two signals for differential amplification thereof to detect changes in the patient's ventilation, from which to identify inordinately reduced ventilation as a potential episode of sleep apnea.2. The device of claim 1 , including:means for sensing consecutive respiration cycles from said detected changes of patient ventilation, and responsive thereto for establishing a predetermined escape interval of time between pairs of successive respiration cycles and for resetting said escape interval upon sensing each respiration cycle, so as to detect a sustained absence of ...

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Номер записи: 42
15-08-2013 дата публикации

EMERGENCY PEDIATRIC ECG LEAD SET WITH INTEGRATED INSTRUCTIONS

Номер: US20130211210A1
Автор: Freeman Curtis
Принадлежит: KONINKLIJKE PHILIPS ELECTRONICS N.V.

A cardiac electrotherapy device is described having an electrode lead set () and an instruction placard () having a set of medical guidance instructions () integrated with the electrode lead wire (). The medical guidance instructions are printed on an elongated readable surface which is attached along its long edge to the electrode lead wire. The invention is particularly useful during cardiac emergencies involving pediatric or infant patients, whose medical dosage limits may be closely correlated with patient length. 1100. A cardiac treatment device electrode lead () comprising:{'b': '120', 'an adhesive skin electrode ();'}{'b': '130', 'a connector () for connecting the electrode to a cardiac treatment device;'}{'b': '160', 'a lead wire () electrically connecting the electrode to the connector;'}{'b': '140', 'a measurement device () disposed along a length of the lead wire by which a patient characteristic relevant to the cardiac treatment is obtained; and'}{'b': '150', 'an index mark () disposed at one end of the measurement device.'}2210. The cardiac treatment device of claim 1 , wherein the measurement device further comprises a medical guidance instruction () disposed at a location on the measurement device claim 1 , the instruction based on a distance from the location to the index mark.3. The cardiac treatment device of claim 2 , further comprising a second medical guidance instruction disposed at a second location on the measurement device claim 2 , the second instruction based on a second distance from the second location to the index mark.4. The cardiac treatment device of claim 1 , wherein the measurement device is comprised of a flexible polymeric strip that is adhesively disposed along the length of the lead wire.5. The cardiac treatment device of claim 1 , wherein the measurement device is integrally molded to the lead wire.6. The cardiac treatment device of claim 2 , wherein the distance correlates approximately to a measured length of a patient claim ...

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Номер записи: 43
15-08-2013 дата публикации

Arthroscopic Surgical Planning and Execution with 3D Imaging

Номер: US20130211232A1
Автор: Armand Mehran, Hungerford Marc, Lepisto Jyri, Murphy Ryan J., Otake Yoshito
Принадлежит: THE JOHNS HOPKINS UNIVERSITY

A method includes obtaining a first three-dimensional (3-D) image of a bone structure, generating a surgical plan based on the first 3-D image and registering the surgical plan to the bone structure to generate a registered surgical plan by obtaining a first 2-D real-time video image of the bone structure and a second 3-D image of the bone structure, and correlating structures from the first 2-D real-time video image and the second 3-D image with the surgical plan. The method also includes obtaining a second 2-D real-time image of the bone structure and overlaying the registered surgical plan onto the second 2-D real-time video image. 1. A method comprising:obtaining a first three-dimensional (3-D) image of a bone structure;generating a surgical plan based on the first 3-D image; obtaining a first 2-D real-time video image of the bone structure and a second 3-D image of the bone structure, and', 'correlating structures from the first 2-D real-time video image and the second 3-D image with the surgical plan;, 'registering the surgical plan to the bone structure to generate a registered surgical plan byobtaining a second 2-D real-time image of the bone structure; andoverlaying the registered surgical plan onto the second 2-D real-time video image.2. The method of claim 1 , wherein the three-dimensional image is generated by at least one of a magnetic resonance imaging (MRI) device and a computed tomography x-ray device.3. The method of claim 1 , wherein generating the surgical plan includes generating a three-dimensional representation of the bone structure.4. The method of claim 3 , wherein the three-dimensional representation of the bone structure includes data distinguishing a portion of the bone structure identified for removal.5. The method of claim 1 , wherein obtaining the first and second real-time images includes inserting an arthroscope into a body at a location corresponding to the bone structure.6. The method of claim 1 , wherein the second 3-D image is ...

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Номер записи: 44
15-08-2013 дата публикации

METHOD FOR MYOCARDIAL SEGMENT WORK ANALYSIS

Номер: US20130211256A1
Автор: Eriksen Morten, Russell Kristoffer, Smiseth Otto A.
Принадлежит: OSLO UNIVERSITETSSYKEHUS HF

The invention relates to medical monitoring apparatuses, methods, and computer programs for determining power or work as a function of time for individual myocardial segments based on strain and pressure measurements. Compared to prior art determinations of determination of mechanical power or work for individual segments, the invention is advantageous as it provides such determination solely from a pressure measurement or estimate and a measurement of strain, preferably by echocardiography, such as speckle tracking ultrasound imaging. This allows a fast, easy and non-invasive determination with high temporal and spatial resolution. A number of indices for segment work can be calculated which can be used as markers for the individual segment function as well as for a selection of patient for CRT. 1. An apparatus for receiving preparing and presenting data related to individual myocardial segment work from tissue strain imaging data , the apparatus comprising:a medical imaging device for non-invasively recording tissue strain imaging data for two or more myocardial segments; and 'calculating mechanical power, P(t), and/or mechanical work, W(t), traces for two or more individual myocardial segments as a function of time for a period comprising the time interval from the beginning of isovolumetric contraction and until the end of isovolumetric relaxation from ventricular tissue strain traces for each of the two or more myocardial segments, and a non-invasively determined pressure trace proportional to a ventricular pressure and in temporal synchrony with the strain traces.', 'an electronic processor capable of215-. (canceled)17. The apparatus according to claim 16 , wherein the mechanical work for segment n claim 16 , W(t) claim 16 , is calculated as:{'br': None, 'i': W', 't', 'P', 't', 'dt′+C, 'sub': n', '0', 'n', '2n, 'sup': 't', '()=∫(′)'}{'sub': '2n', 'wherein t′ is an integration variable and Cis a constant for segment n.'}18. The apparatus according to claim 1 , ...

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Номер записи: 45
15-08-2013 дата публикации

ESOPHAGEAL HEAT SENSORS

Номер: US20130211282A1
Автор: Bunch T. Jared, Orr Troy J.
Принадлежит:

Heat sensors can be positioned within the esophagus of a patient so as to monitor temperature changes during ablation procedures in the heart. Some heat sensors can include a wire that defines an extended heat sensing region capable of detecting a change in the local temperature. Some heat sensors can be conformable to an inner surface of the esophageal wall to maintain contact therewith or to be in close proximity thereto. 1. A heat sensing assembly comprising:an electrical wire that comprises a material having a resistivity that varies with temperature; andan electrically insulating structure encapsulating the electrical wire, wherein the electrically insulating structure is configured to isolate the electrical wire from an electrically conductive substance when the heat sensing assembly is deployed, and wherein the electrically insulating structure is configured to permit heat transfer to, from, or both to and from the electrical wire,wherein the electrical wire and the electrically insulating structure are flexible about at least one axis,wherein the electrical wire extends in a longitudinal direction and in one or more lateral directions that are transverse to the longitudinal direction to define a heat sensing region when the heat sensing assembly is deployed, andwherein the heat sensing assembly is sensitive to heating occurring at a portion of the heat sensing region due to a change in a total electrical resistance of the electrical wire.2. The heat sensing assembly of claim 1 , wherein the electrically insulating structure comprises a substrate and a superstrate claim 1 , wherein the electrical wire is laminated between the substrate and the superstrate claim 1 , and wherein each of the substrate and the superstrate are flexible about the at least one axis.3. The heat sensing assembly of claim 2 , further comprising a first electrical junction and a second electrical junction claim 2 , wherein the electrical wire extends between the first and second ...

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Номер записи: 46
15-08-2013 дата публикации

FLUIDIC ESOPHAGEAL HEAT SENSORS

Номер: US20130211283A1
Автор: Bunch T. Jared, Orr Troy J.
Принадлежит:

Heat sensors can be positioned within the esophagus of a patient so as to monitor temperature changes during ablation procedures in the heart. Some heat sensors can include one or more fluid passageways that define an extended heat sensing region capable of detecting a change in the local temperature. Some heat sensors can be conformable to an inner surface of the esophageal wall to maintain contact therewith or to be in close proximity thereto. 1. A heat sensing assembly comprising:a support structure that is configured to extend in a longitudinal direction when positioned within an anatomical vessel of a patient; anda fluid passageway carried by the support structure and defining a heat sensing region that is configured to extend in the longitudinal direction and in one or more lateral directions that are transverse to the longitudinal direction when the heat sensing assembly is deployed within the anatomical vessel,wherein a portion of the heat sensing assembly that includes the support structure and the fluid passageway is flexible about at least one axis,wherein the support structure is configured to permit heat to pass through it to or from the fluid passageway to alter a temperature of a fluid positioned in the fluid passageway when the heat sensing assembly is deployed, andwherein the heat sensing assembly is configured to detect when a change in heat occurs at only a portion of the heat sensing region.2. The heat sensing assembly of claim 1 , wherein the fluid passageway is configured to permit flow of heat transfer fluid therein when the heat sensing assembly is in use claim 1 , and wherein the support structure is configured to permit heat from a wall of an anatomical vessel to pass through the support structure into the fluid passageway to be transferred away from the wall of the anatomical vessel via the heat transfer fluid when the heat sensing assembly is in use.3. The heat sensing assembly of claim 1 , wherein the support structure has a natural ...

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Номер записи: 47
22-08-2013 дата публикации

Electrode Device, in Particular for Cardiovascular Application

Номер: US20130217992A1
Автор: Bartels Klaus, Guenther Thomas, Steglich Carsten
Принадлежит: BIOTRONIK SE & Co. KG

An electrode device, in particular for cardiovascular applications, includes an elongated electrode body made from an insulating material, a plurality of electrodes for detecting electrocardiological signals and/or for outputting electrocardiological stimulus signals, and supply line, in particular non-elastic cables or strands, which serve for electrically connecting the electrodes, which supply lines are guided in each case in the electrode body, preferably in associated lumina. Furthermore, a compensating hose section is provided which is inserted in a parting point in the electrode and has a maximum outer diameter that corresponds to the electrode body, wherein helically shaped receptacles, for each supply line, are incorporated in the compensating hose section, and the compensating hose section, at its joining sides facing toward the electrode body, is connected in a hermetically sealed manner to the electrode body. 1. An electrode device for cardiovascular applications , comprising:an elongated electrode body made from an insulating material;a plurality of electrodes for detecting electrocardiological signals and/or for out-putting electrocardiological stimulus signals;supply lines, which include non-elastic cables or strands, serving for electrically connecting the electrodes, wherein the supply lines are in each case guided in the electrode body in associated lumina; anda compensating hose section which is inserted in a parting point in the electrode body and has a maximum outer diameter that corresponds to the electrode body, wherein helically shaped receptacles for each supply line are incorporated in the compensating hose section, and the compensating hose section, at its joining sides facing toward the electrode body, is connected in a hermetically sealed manner to the electrode body.2. The electrode device according to claim 1 , wherein the receptacles are configured as helically shaped lumina.3. The electrode device according to claim 1 , wherein the ...

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Номер записи: 48
22-08-2013 дата публикации

MRI Coil For Imaging Of The Breast And Thoracic Area

Номер: US20130218000A1
Автор: COPPENS Daniel D., RABENO David R.
Принадлежит: QFIX SYSTEMS, LLC

The present invention provides a novel MRI coil configuration for breast cancer imaging in preparation for radiation therapy planning and treatment. Both an adjustable anterior and posterior coil sets are described. The coil sets are supported and configured so as not to affect the accurate and repeatable positioning of the patient and breasts. The coil sets are removable so that they can be extracted before radiation therapy treatment commences. 2. The device of wherein the at least one anterior coil is a rigid coil.3. The device of wherein the at least one anterior coil is a flexible coil.4. The device of further comprising a second MRI coil attached to the top or bottom surface of the platform claim 1 , wherein the second coil is attached posterior to the patient.5. The device of wherein the second posterior coil is a rigid coil.6. The device of wherein the second posterior coil is a flexible coil.7. The device of wherein the platform is an angling back support.8. The device of compatible with diagnostic imaging claim 1 , MRI claim 1 , PET claim 1 , CT claim 1 , x-ray and radiation therapy treatment.9. The device of wherein the MRI coil is supported by at least one of; a rigid attachment claim 1 , a telescoping cylinder claim 1 , a rotatable member claim 1 , or an articulating member.10. The device of wherein the MRI coil is supported by at least one of; a rigid attachment claim 4 , a telescoping cylinder claim 4 , a rotatable member claim 4 , or an articulating member.11. The device of wherein the coil set support can be quickly and easily attached and removed from the platform. The present application claims priority from U.S. Provisional Application Ser. No. 61/599,946, filed on 17 Feb. 2012.The present invention relates to magnetic resonance imaging (MRI) systems and, in particular, to the radio-frequency (RF) coils used in such systems.Magnetic Resonance Imaging (MRI) provides one of the best imaging technologies for distinguishing soft tissue. This is ...

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Номер записи: 49
22-08-2013 дата публикации

DOSIMETER, THERAPEUTIC APPARATUS, AND COMPUTER PROGRAM PRODUCT FOR MEASURING RADIATION DOSAGE TO A SUBJECT DURING MAGNETIC RESONANCE IMAGING

Номер: US20130218001A1
Автор: Uhlemann Falk
Принадлежит: KONINKLIJKE PHILIPS ELECTRONICS N.V.

A dosimeter () for measuring radiation dosage to a subject () during a magnetic resonance imaging guided radiation therapy session, the dosimeter comprising: an outer surface () adapted for receiving a surface () of the subject, and discrete cells () each filled with a magnetic resonance radiation dosimeter. 1. A dosimeter for measuring radiation dosage to a subject during a magnetic resonance imaging guided radiation therapy session , the dosimeter comprising:an outer surface adapted for receiving a surface of the subject, anddiscrete cells each filled with a magnetic resonance radiation dosimeter.2. The dosimeter of claim 1 , wherein the dosimeter further comprises a thermal insulation layer between the outer surface and the discrete cells.3. The dosimeter of claim 1 , wherein the dosimeter is a vacuum pillow wherein the dosimeter further comprises polystyrene foam balls wherein the discrete cells each comprise shells filled with the magnetic resonance radiation dosimeter claim 1 , wherein within the vacuum pillow the discrete cells and the polystyrene foam halls are mixed.4. The dosimeter of claim 2 , wherein the dosimeter is a pad claim 2 , and wherein the discrete cells are dispersed uniformly within the thermal insulation layer.5. The dosimeter of claim 2 , wherein the dosimeter is a blanket claim 2 , wherein the discrete cells are arranged in a continuous layer claim 2 , and wherein the thermal insulation layer surrounds the continuous layer.6. The dosimeter of claim 1 , wherein the dosimeter is adapted to be mounted to a patient support of a magnetic resonance imaging system.7. The dosimeter of claim 1 , wherein the dosimeter comprises two parts claim 1 , wherein each of the two parts has an outer surface adapted for receiving two opposing surfaces of the subject8. The dosimeter of claim 1 , wherein the magnetic resonance dosimeter is any one of the following: a Fricke dosimeter and a polymer dosimeter.9. A therapeutic apparatus comprising:a magnetic ...

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Номер записи: 50
22-08-2013 дата публикации

Ultrasound Medical System and Method

Номер: US20130218013A1
Автор: Barthe Peter, Faidi Waseem, Jaeger Paul, Makin Inder, Mast Douglas, Messerly Jeffery, OConner Brian, Park Christopher, Runk Megan, Slayton Michael
Принадлежит:

An ultrasound medical system includes an interstitial end effector. The interstitial end effector is interstitially insertable into patient tissue, includes at least one medical-treatment ultrasound transducer, and includes at least one end-effector-tissue-track ablation device. One method for ultrasonically treating a lesion in a patient includes the steps of obtaining the interstitial end effector and inserting it into the patient creating a tissue track which is surrounded by patient tissue and which ends at the distal end of the inserted interstitial end effector. Other steps include ultrasonically ablating the lesion using the at-least-one medical-treatment ultrasound transducer, using the at-least-one end-effector-tissue-track ablation device to ablate the patient tissue surrounding the tissue track along substantially the entire tissue track, and withdrawing the end effector from the patient. 1. An ultrasound treatment system comprising:a probe comprising a treatment ultrasound transducer configured to treat patient tissue;a non-ultrasound tissue-property measuring sensor coupled to the probe; anda controller configured to communicate with the probe and the non-ultrasound tissue-property measuring sensor;wherein the non-ultrasound tissue-property measuring sensor is positioned to be in contact with the patient tissuewherein the controller is configured to control the probe and to receive feedback from the non-ultrasound tissue-property measuring sensor.2. The ultrasound treatment system according to claim 1 , wherein the non-ultrasound tissue-property measuring sensor is configured to measure tissue temperature.3. The ultrasound treatment system according to claim 2 , wherein the non-ultrasound tissue-property measuring sensor is at least one of a thermistor claim 2 , and a thermocouple.4. The ultrasound treatment system according to claim 1 , wherein the non-ultrasound tissue-property measuring sensor is configured to measure tissue electrical impedance.5. ...

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Номер записи: 51
22-08-2013 дата публикации

BELLY-TYPE BREATH AUXILIARY DEVICE

Номер: US20130218041A1
Автор: LIOU Kevin
Принадлежит:

The present invention discloses a belly-type breath auxiliary device comprising body, belt assembly and breath monitoring unit. The body includes a box. The box positions the breath monitoring unit, and connects two end of the belt assembly by elastic members. The breath monitoring unit has movement detecting unit, signal processing unit and warning unit. The movement detecting unit produces a signal when detecting the third connecting member moves to a specific position, and the signal processing unit determines the user finishing one time of effective breath by the signal. The warning unit acts to remind the user keeping his belly-type breath when the movement detecting unit does not detect the third connecting member moving to the specific position within a specific time. 1. A belly-type Breath auxiliary device comprising:a body comprising a box and a cover; a top of the box being defined a first fluting thereon, two lateral sides of the box being defined a trough thereon; an inner side of the box being defined a holding trough for receiving batteries, a first connecting member and a second connecting member; the first fluting forming a rectangular trough when the cover and the box cover with each other;a belt assembly comprising a fastener, a strip, a third connecting member and a fourth connecting member; the fastener being positioned on the strip; the third connecting member and the fourth connecting member being positioned at two ends of the belt assembly and penetrating one trough respectively, so that the body being attached on the belt assembly; the belt assembly being put around a belly of a user, and the body being closed the belly;a first elastic member with two ends connecting with the first connecting member and the third connecting member respectively;a second elastic member with two ends connecting with the second connecting member and the fourth connecting member respectively;a breath monitoring unit locating on the box and comprising a movement ...

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Номер записи: 52
22-08-2013 дата публикации

HEMOSTASIS INSTRUMENT

Номер: US20130218069A1
Автор: Enderle Markus D., Fischer Klaus, Neugebauer Alexander
Принадлежит: ERBE ELEKTROMEDIZIN GMBH

A hemostasis instrument for actively stopping the bleeding, in particular after an open, laparoscopic, or endoscopic operation on a patient, having several hemostasis components. The hemostasis instrument has at least the following hemostasis components:—a thermal hemostasis device for tissue coagulation by producing a temperature above the coagulation temperature of biological tissue by means of a coagulation electrode;—a biochemical hemostasis device for producing a silent electric discharge by means of at least one discharge electrode, and an insulating device, wherein the insulating device is arranged between the discharge electrode and the tissue to be treated;—a supplying device for supplying substances that influence blood clotting to the tissue to be treated, and—a supply device for supplying noble gas to the tissue to be treated. 1. A hemostasis instrument for actively stopping bleeding , in particular after an open , laparoscopic or endoscopic operation on a patient , comprising a plurality of hemostasis components , wherein at least the following hemostasis components are provided:a thermal hemostasis apparatus for tissue coagulation by generating a temperature above the coagulation temperature of biological tissue by means of a coagulation electrode;a biochemical hemostasis apparatus for generating a dielectric barrier discharge by means of at least one discharge electrode and an insulation apparatus, wherein the insulation apparatus is arranged between the discharge electrode and the tissue to be treated;a supply apparatus for supplying substances influencing blood clotting to the tissue to be treated, anda supply apparatus for supplying noble gas to the tissue to be treated.2. The hemostasis instrument as claimed in claim 1 , wherein the hemostasis instrument comprises a further hemostasis component in the form of a heating apparatus for endogenous or exogenous heating of the blood during a dielectric barrier discharge to a temperature below the ...

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Номер записи: 53
12-09-2013 дата публикации

Biomarker Sampling in the Context of Neuromodulation Devices, Systems, and Methods

Номер: US20130237780A1
Автор: Beasley Rudy, HEZI-YAMIT Ayala, Silver Michele Lee, Storment Christopher W.
Принадлежит: Medtronic Ardian Luxembourg S.a.r.l.

Methods for treating a patient using therapeutic renal neuromodulation and associated devices, systems, and methods are disclosed herein. One aspect of the present technology is directed to biomarker sampling in the context of neuromodulation devices, systems, and methods. Some embodiments, for example, are directed to catheters, catheter systems, and methods for sampling biomarkers that change in response to neuromodulation. A system can include, for example, an elongated shaft and a neuromodulation and sampling assembly having a neuromodulation and a sampling element. 1. A system , comprising:a neuromodulation element configured to modulate nerves at or otherwise proximate to a renal artery of a patient;an elongated shaft having a first portion configured to be intravascularly positioned while the neuromodulation element modulates the nerves, and a second portion proximal to the first portion, the second portion configured to be extracorporeally positioned while the neuromodulation element modulates the nerves;an occlusion member extending around a segment of the first portion;a sampling port distal to the segment of the first portion;a sampling lumen extending from the sampling port toward the second portion;an inflation opening within the occlusion member; andan inflation lumen extending from the inflation opening toward the second portion.2. The system of claim 1 , further comprising an analyzer configured to analyze a biological sample from the patient for a biological parameter that changes in response to modulating the nerves.3. The system of wherein:the analyzer is operably connected to the second portion; andthe sampling lumen extends from the sampling port along the shaft to the analyzer.4. The system of claim 2 , further comprising a handle coupled to the second portion claim 2 , wherein the analyzer is carried by the handle.5. The system of wherein the analyzer includes an indicator configured to indicate a status of the biological parameter claim 2 , a ...

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Номер записи: 54
12-09-2013 дата публикации

System and methods for locating and ablating arrhythomogenic tissues

Номер: US20130237791A1
Автор: Chen Peter C., de la Rama Alan, Hata Cary K., Tran Vivian
Принадлежит: St. Jude Medical, Atrial Fibrillation Division, Inc.

The disclosure relates to a variety of systems and methods for sensing electrical events about a selected annulus region of the heart and for treating tissue in the selected annulus region. Wherein the system includes a first catheter that has an expandable member, an ablation element, and a lumen configured to allow a second catheter therethrough. The second catheter includes a distal section in a ring shape and a plurality of electrodes coupled around the ring. Optionally a second lumen can be included through the first catheter that allows for contrast media to be delivered to the distal end of the system. 120-. (canceled)21. A system for sensing electrical events about a selected intrabody annulus region and for treating tissue in the selected annulus region , comprising:a first catheter and a second catheter; a first handle assembly;', 'a first shaft having a first proximal end coupled to the first handle assembly, and a first distal end, the first shaft extending along a first axis;', 'a first lumen extending entirely through the first distal end of the first shaft along the first axis;', 'a second lumen extending entirely through the first distal end of the first shaft along the first axis;', 'an ablation element provided adjacent the first distal end of the first shaft;', 'an expandable member adjacent the first distal end; and', 'wherein the first lumen is adapted to receive the second catheter therethrough;, 'the first catheter comprising a second handle assembly;', 'a second shaft having a second proximal end coupled to the second handle assembly, and a second distal end, the second shaft of the second catheter extending along a second axis; and', 'a distal ring provided at the second distal end of the second shaft of the second catheter and oriented substantially perpendicular to the second axis of the second shaft of the second catheter, the distal ring having a plurality of discrete electrodes positioned about the distal ring of the second catheter., ' ...

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Номер записи: 55
12-09-2013 дата публикации

Method and Apparatus for Detecting Change in Intrathoracic Electrical Impedance

Номер: US20130237792A1
Автор: Stadler Robert W., WANG LI
Принадлежит: Medtronic, Inc.

A method and apparatus for detection of changes in impedance a patient that includes generating measured impedances, generating an adaptive baseline trend of the measured impedances corresponding to a first time period, generating a short term trend of the measured impedances corresponding to a second time period less than the first time period, determining changes in relative position of the short term trend and the baseline trend, the determined changes in relative position corresponding to determining intersecting of the baseline trend by the short term trend, determining differences between the baseline trend and calculated period average impedances, and accumulating, in response to determining no intersecting of the baseline trend by the short term trend, the determined differences between the baseline trend and the calculated period average impedances. 1. An implantable medical device , comprising:a plurality of electrodes;an output circuit outputting a plurality of output pulse signals along a vector formed by electrodes of the plurality of electrodes;a measurement circuit generating a corresponding plurality of measurement signals in response to the plurality of output pulse signals; anda microprocessor configured to determine a plurality of period average impedances in response to the plurality of output pulse signals and the plurality of measurement signals corresponding to a predetermined time period, determine an adaptive baseline trend of period average impedances of the plurality of period average impedances corresponding to a first time period, determine a short term trend of period average impedances of the plurality of period average impedances corresponding to a second time period different from the first time period, determine changes in relative position of the short term trend and the baseline trend, determine differences between the baseline trend and the calculated period average impedances, and accumulate, in response to determining no ...

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Номер записи: 56
12-09-2013 дата публикации

METHOD AND APPARATUS FOR DETECTING CARDIAC SIGNALS

Номер: US20130237793A1
Автор: Chapman Darius George, Farrugia Steven Paul
Принадлежит: RESMED LIMITED

Devices and systems provide methods for detecting cardiac signals from head or facial biopotential sensors. In one embodiment, a facial biopotential signal is measured by a set of sensors. A processor derives a cardiac signal from the facial biopotential signal. Optionally, heart rate is detected from the cardiac signal. Heart rate variability may be determined and evaluated by the processor to generate warnings or messages from the evaluation. One or more head or facial biopotential electrodes for measuring the facial biopotential signal may be integrated in or at a contact surface of head support structures such as a headgear support or respiratory treatment mask. In some such embodiments a controller of a respiratory treatment apparatus may serve as a cardiac signal detector by processing the facial biopotential signal from the sensors and may make control adjustments or generate warnings based on an evaluation of detected signals. 1. A method for detecting a cardiac signal comprising:measuring a facial biopotential signal from a set of electrodes connected to a patient; anddetecting by a processor a cardiac signal from the facial biopotential signal.2. The method of wherein the measuring comprises determining a voltage difference between signals of at least two electrodes of the set of electrodes.32. The method of any one of - wherein the measuring comprises determining field strength with the set of electrodes claims 1 , the set of electrodes comprising a non-contact sensor.43. The method of any one of - wherein the measuring comprises measuring current between two electrodes of the set of electrodes.54. The method of any one of - wherein the detecting comprises signal processing of the facial biopotential signal.6. The method of wherein the processing comprises filtering the facial biopotential signal.76. The method of any one of - further comprising determining a heart rate from the cardiac signal.8. The method of wherein the determining the heart rate ...

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Номер записи: 57
12-09-2013 дата публикации

HEMOSTASIS APPARATUS AND METHOD

Номер: US20130237866A1
Автор: Cohen Mauricio Gabriel, Downward, IV James G., Korotko Joseph R., Ryan James Patrick
Принадлежит: Accumed Systems, Inc.

The apparatus and method for hemostasis that informs the provider as to whether the appropriate magnitude of pressure is being applied to a puncture site on a patient. A visual pulse indicator can visually convey whether or not there is proper blood flow at the puncture site based on the pulsing motion encountered by the visual pulse indicator on the puncture site. The visual pulse indicator can potentially factor in a variety of different input parameters in displaying information that is useful to providers. 1. A method of performing hemostasis on a puncture site on a patient , comprising:positioning a visual pulse indicator relative to the puncture site of the patient;viewing an indication from the visual pulse indicator, wherein the indication is associated with a blood flow attribute relating to the patient; andselectively adjusting a pressure magnitude over the puncture site, wherein the selective adjustment is influenced by the blood flow attribute indicated by the visual pulse indicator.2. The method of claim 1 , wherein the hemostasis is performed as part of a transradial catheterization on the patient.3. The method of claim 1 , wherein the blood flow attribute detected by the visual pulse indicator is a pulsing motion on the puncture site.4. The method of claim 3 , wherein the visual pulse indicator is a reflective foil.5. The method of claim 3 , wherein the visual pulse indicator includes two Moiré line patterns.6. The method of claim 1 , further comprising setting a timer component for signaling a future point in time in which the pressure magnitude is to be adjusted.7. An apparatus for use over a puncture site for a patient during hemostasis claim 1 , comprising:a visual pulse indicator that provides for being positioned relative to the puncture site, wherein said visual pulse indicator provides for displaying a plurality of indications that relate to a plurality of blood flow attributes;said plurality of indications including a first indication and a ...

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Номер записи: 58
19-09-2013 дата публикации

System for Delivering Conformal Radiation Therapy While Simultaneously Imaging Soft Tissue

Номер: US20130245425A1
Автор: Dempsey James F.
Принадлежит: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.

Devices and processes for performing magnetic resonance imaging of the anatomy of a patient during radiation therapy to measure and control the radiation dose delivered to the patient. 1. A radiation treatment system , comprising: a) control the irradiating device to deliver ionizing radiation to the subject; and', 'b) control the magnetic resonance imaging system to acquire the 3D images of the subject; and a processor configured to determine an actual dose deposition in the subject from the 3D images and the delivered ionizing radiation., 'an irradiating device configured to deliver ionizing radiation to a subject from one or more radiation sources external to the subject; a magnetic resonance imaging system configured to acquire a sequence of 3D images of the subject fast enough to capture intra-fraction organ motions; a controller in communication with the irradiating device and the magnetic resonance imaging system such that the controller can substantially simultaneously'}2. The radiation treatment system of claim 1 , wherein the controller is configured to reoptimize the delivery of ionizing radiation based on the determined actual dose deposition.3. The radiation treatment system of claim 1 , wherein the controller is configured to stop the delivery of ionizing radiation if the actual dose deposition evidences a dosimetric error.4. The radiation treatment system of claim 1 , further comprising a multi-leaf collimator configured to rapidly adjust the delivery of ionizing radiation to account for intra-fraction organ motions.5. The radiation treatment system of claim 1 , wherein the system is constructed and arranged such that the actual dose deposition is used to reoptimize an intensity modulated radiation therapy for a subject.6. The radiation treatment system of claim 1 , wherein the magnetic resonance imaging system is constructed and arranged to acquire metabolic or physiological information substantially simultaneously to the delivery of ionizing ...

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Номер записи: 59
19-09-2013 дата публикации

SYSTEM AND METHODS FOR ASSESSING HEART FUNCTION

Номер: US20130245473A1
Автор: ARLESS Steven G., Harold Wodlinger, JIA Ping, RAMANATHAN Charulatha, STROM Maria
Принадлежит:

Systems and methods can be used to provide an indication of heart function, such as an indication of mechanical function or hemodynamics of the heart, based on electrical data. For example, a method for assessing a function of the heart can include determining a time-based electrical characteristic for a plurality of points distributed across a spatial region of the heart. The plurality of points can be grouped into at least two subsets of points based on at least one of a spatial location for the plurality of points or the time-based electrical characteristics for the plurality of points. An indication of synchrony for the heart can be quantified based on relative analysis of the determined time-based electrical characteristic for each of the at least two subsets of points. 1. A method for assessing a function of a patient's heart , comprising:determining a time-based electrical characteristic for a plurality of points corresponding to at least one spatial region of the heart;grouping the plurality of points into at least two subsets of points based on at least one of a spatial location for each of the plurality of points or the time-based electrical characteristic for each of the plurality of points; andquantifying an indication of synchrony for the heart based on relative analysis of the determined time-based electrical characteristic for each of the at least two subsets of points.2. The method of claim 1 , wherein the at least two subsets of points correspond to different chambers of the heart claim 1 , the method further comprising computing an index having at least one value representing synchrony between the different chambers.3. The method of claim 2 , wherein the different chambers of the heart comprise the left ventricle and the right ventricle.4. The method of claim 2 , wherein the quantifying further comprises:computing a first statistical parameter for each of the plurality of points associated with a first chamber of the heart,computing a second ...

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Номер записи: 60
19-09-2013 дата публикации

MINIMALLY INVASIVE DETERMINATION OF COLLATERAL VENTILATION IN LUNGS

Номер: US20130245484A1
Автор: ALJURI Nikolai, Davis Kirk, Perkins Rodney C., Soltesz Peter, SURJAN George, Wondka Anthony
Принадлежит: PulmonX Corporation

Minimally invasive methods, systems and devices are provided for qualitatively and quantitatively assessing collateral ventilation in the lungs. In particular, collateral ventilation of a target compartment within a lung of a patient is assessed by advancement of a catheter through the tracheobronchial tree to a feeding bronchus of the target compartment. The feeding bronchus is occluded by the catheter and a variety of measurements are taken with the use of the catheter in a manner which is of low risk to the patient. Examples of such measurements include but are not limited to flow rate, volume and pressure. These measurements are used to determine the presence of collateral ventilation and to quantify such collateral ventilation. 1. A method for determining the function or malfunction of an endobronchial prosthesis positioned within a lung passageway of a patient , said method comprising:occluding the lung passageway proximally of the endobronchial prosthesis;allowing the patient to breathe air without any markers; andmeasuring air flow or accumulation from the lung passageway over time wherein said measurement is correlative to the function or malfunction of the endobronchial prosthesis.2. A system for detecting collateral ventilation into a lung compartment in a patient , said system comprising:a catheter adapted to be introduced transtracheally to a bronchus leading to a target lung compartment;an occlusion member on a distal region of the catheter, said occlusion member being adapted to selectively occlude the bronchus; anda flow measurement sensor on the catheter to detect flow of air from the isolated compartment as the patient exhales.3. A system for detecting collateral ventilation into a lung compartment in a patient , said system comprising:a catheter adapted to be introduced transtracheally to a bronchus leading to a target lung compartment;an occlusion member or a distal region of the catheter, said occlusion member being adapted to selectively ...

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Номер записи: 61
26-09-2013 дата публикации

APPARATUS AND METHOD FOR TREATMENT OF PAIN WITH BODY IMPEDANCE ANALYZER

Номер: US20130253365A1
Автор: Crosson John, Weinkle David
Принадлежит: NewLife Sciences LLC

A patient treatment unit and method analyzes and treats pain in tissues by applying an electrical pulse train to the affected tissue. The impedance of the affected tissue is measured, and the measured impedance is correlated to a level of pain in the patient. The pulse train is further applied in response to the measured impedance to reduce the patient's pain. The patient treatment unit includes a probe stimulus generator that outputs the pulse train. The treatment unit also includes a pair of probes for contacting the patient's body and receiving the pulse train. The pulse has improved shaping based on isolation of high voltage from a low voltage control. The unit further includes a body impedance analysis circuit that senses voltage and current via the probes when the probes are contacting the patient and observe the impedance. A monitor is electrically coupled to the body impedance analysis circuit and provides an indication of the measured impedance indicative of the patient's level of pain in real-time. 1. A patient treatment unit for analyzing and treating pain in human or animal tissues , the treatment unit comprising:a probe stimulus generator circuit that outputs a sequence of electrical pulses, the electrical pulses having a pulse width and a pulse frequency, the probe stimulus generator controlling the pulse frequency and the pulse width of the electrical pulses;a primary vibrating spherical probe and a secondary spherical probe for contacting a body of a patient and electrically coupled to the probe stimulus generator to receive the sequence of electrical pulses;a body impedance analysis circuit that senses voltage or current via the primary vibrating spherical probe and the secondary spherical probe in real-time as the sequence of electrical pulses are applied to the tissues when the probes are contacting the body of the patient;a monitor device electrically coupled to the body impedance analysis circuit that provides an indication of the sensed voltage ...

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Номер записи: 62
03-10-2013 дата публикации

THERAPEUTIC APPARATUS COMPRISING A RADIOTHERAPY APPARATUS, A MECHANICAL POSITIONING SYSTEM, AND A MAGNETIC RESONANCE IMAGING SYSTEM

Номер: US20130261430A1
Автор: Uhlemann Falk
Принадлежит: KONINKLIJKE PHILIPS ELECTRONICS N.V.

A therapeutic apparatus () comprising a radiotherapy apparatus (), a mechanical positioning system, and a magnetic resonance imaging system (). The radiotherapy apparatus comprises a radiotherapy source (). The radiotherapy apparatus is adapted for rotating the radiotherapy source at least partially around a subject support. The therapeutic apparatus further comprises a memory containing machine executable instructions (). Execution of the instructions causes a processor to repeatedly: acquire () the magnetic resonance data using the magnetic resonance imaging system; reconstruct () a magnetic resonance image () from the magnetic resonance data; register () a location () of the target zone in the magnetic resonance image; generate () radiotherapy control signals () in accordance with the location of the registered target zone; generate () mechanical positioning control signals () in accordance with the registered target zone and the radiotherapy control signals; and send () the radiotherapy control signals to the radiotherapy system and send () the mechanical positioning control signals to the mechanical positioning system. 1. A therapeutic apparatus comprising:a radiotherapy apparatus for treating a target zone of a subject, wherein the radiotherapy apparatus comprises a radiotherapy source for directing electromagnetic radiation into the target zone;a mechanical positioning system for positioning a subject support;a magnetic resonance imaging system for acquiring magnetic resonance data from an imaging zone, wherein the target zone is within the imaging zone, wherein the magnetic resonance imaging system comprises a magnet for generating a magnetic field within the imaging zone, wherein the radiotherapy apparatus is adapted for rotating the radiotherapy source at least partially around the subject support;a processor for controlling the therapeutic apparatus; acquire the magnetic resonance data using the magnetic resonance imaging system;', 'reconstruct a magnetic ...

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Номер записи: 63
10-10-2013 дата публикации

DIAGNOSTIC METHOD FOR CONNECTIVE TISSUE AND ITS APPLICATION

Номер: US20130266550A1
Автор: CHERKASOV Vladimir Ryurikovich, KOPNIN Pavel Borisovich, ZORIN Vadim Leonidovich, ZORINA Alla Ivanovna
Принадлежит: OBSHHESTVO S OGRANICHENNOI OTVETSTVENNOST'YU "VITACEL"

The present invention relates to medicine and is used to evaluate conditions and to detect connective tissue pathology (and/or organ) by clonal analysis. The present invention relates to aesthetic medicine and is used for correction of aging skin changes. The method includes: cultivation of substrate-dependent cell colonies of analyzed tissue and/or organ, at conditions which provide formation of discrete colonies applicable for visualization, statistically reliable analysis of derived colonies, determination of at least one parameter which characterizes regenerative potential of population of substrate dependent cells, determination of at least one parameter which characterizes proliferative potential of population of substrate dependent cells, and processing of obtained results which allows to evaluate regenerative ability of patient's tissue and/or organ. The method provides objective qualitative characteristics of both the proliferative and regenerative potential which allows evaluating the regenerative potential of primary tissue (and/or organ) without complex and expensive instrumental studies. A computer based system for performing the present method is also provided. 1. A method of evaluation of connective tissue and/or organ status , comprising:a) cultivating substrate-dependent cell colonies of analyzed tissue and/or organ at conditions which allow formation of discrete colonies,b) conducting statistically reliable analysis of the formed colonies,c) determining at least one parameter which characterizes regenerative potential of the substrate-dependent cells,d) determining at least one parameter which characterizes proliferative potential of the substrate-dependent cells, ande) processing results obtained in (a)-(d), thereby evaluating the regenerative potential of the patient's tissue and/or organ.2. The method according to claim 1 , wherein ability of the substrate-dependent cells to form colonies is used as a parameter which characterizes the ...

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Номер записи: 64
10-10-2013 дата публикации

SYSTEM FOR RECORDING ELECTRONEUROGRAPHIC ACTIVITY

Номер: US20130267816A1
Автор: Eder Clemens Florian
Принадлежит: NEURODAN A/S

A system for recording electroneurographic activity comprising at least three neurosense electrodes capable of sensing a nerve signal from a peripheral nerve and means for receiving and processing the sensed nerve signal to identify a signal indicative of a specific action being a movement of a body part performed by the patient and for producing a control signal in response thereto featuring means for rejection of signals originating from biological interference sources without affecting the electroneurographic activity measured. 1. A system for recording electroneurographic activity comprising:At least three electrodes, adapted to be placed along the longitudinal orientation of a peripheral nerve said electrodes capable of sensing a nerve signal,Means for receiving and processing the sensed nerve activity and for producing a control signal in response theretoCharacterized in,that the system has means for active rejection of signals originating from biological interference sources without affecting the measurement of electroneurographic activity.2. A system according to claim 1 ,Characterized in,that the arrangement for biological interference rejection includes means for compensating the impedance of the end electrodes in order to provide a low-impedance shunt path for the interference source.3. A system according to claim 2 ,Characterized in,that an additional pair of electrodes is arranged in the vicinity of the end electrodes.4. A system according to or claim 2 ,Characterized in,that the system includes means for measuring the value of the biological interference voltage.5. A system according to claim 4 ,Characterized in,that the system is including a regulated bipolar current- or voltage source that based on the measured biological interference voltage applies a corresponding voltage or current of reverse polarity to the end electrodes.6. A system according to any preceding claims claim 4 ,Characterized in,that the system is including at least one negative ...

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Номер записи: 65
10-10-2013 дата публикации

MRI COMPATIBLE VASCULAR OCCLUSIVE DEVICES AND RELATED METHODS OF TREATMENT AND METHODS OF MONITORING IMPLANTED DEVICES

Номер: US20130267832A1
Автор: Arepally Aravind, Karmarkar Parag V.
Принадлежит:

Implantable aneurysm-sac treatment devices include an implantable coil body configured and sized to reside in a sac of an aneurysm. The body has an inductance and capacitance. The capacitance is selected so that the coil resonates at a Larmor frequency of a predefined magnetic field strength. 116-. (canceled)17. An MRI system for evaluating an aneurysm in vivo , comprising: at least one implantable RF resonator configured and sized to reside in an intracranial aneurysm sac in a patient , wherein the at least one RF resonator has a resonant frequency corresponding to an operating frequency associated with magnetic field strength of an MRI scanner system; a body coil in communication with an RF excitation source associated with the MRI scanner system , the body coil disposed on the patient the body coil being configured to inductively couple with the at least one RF resonator to transmit RF excitation pulses comprising low flip angle pulses , from the RF excitation source inside of and proximate the at least one RF resonator; and a surface coil in communication with the MRI scanner system and the at least one RF resonator , wherein , in operation , the at least one RF resonator picks up local MR signal data and cooperates with the surface coil to amplify local signal data from the RF resonator.18. An embolic vascular occlusion device , comprising: a microcoil configured and sized for implantation in an aneurysm sac; and at least one MEMS pressure sensor held by the microcoil.19. A method of obtaining image data to guide filling an aneurysm sac with embolic material , comprising: obtaining MRI signal data from an internal implantable RF resonator disposed proximate an aneurysm sac; and filling the sac with a selected embolic material using the obtained MRI signal data.20. A method according to claim 19 , wherein the obtaining step is carried out in substantially real time during the filling step so that the sac can be filled to a desired level without unduly over or ...

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Номер записи: 66
10-10-2013 дата публикации

SYSTEM AND METHOD FOR DETERMINING ONE OR MORE BREATHING PARAMETERS OF A SUBJECT

Номер: US20130267862A1
Автор: Jaffe Michael Brian, Orr Joseph Allen
Принадлежит: KONINKLIJKE PHILIPS ELECTRONICS N.V.

A system is configured to determine one or more breathing parameters of a subject, such as one or both of end-tidal carbon dioxide concentration and/or breath rate. The system is configured to make a plurality of preliminary determinations of an individual breathing parameter according to a plurality of different algorithms. A final determination of the breathing parameter is obtained by selecting one of the preliminary determinations based on therapy parameters, gas parameters, and/or other parameters that impact the accuracy and/or precision of the different algorithms. 1. A system configured to determine a breathing parameter of a subject receiving therapy , the system comprising:one or more sensors configured to generate output signals conveying information related to one or more gas parameters of the gas at or near the airway of the subject; and a therapy parameter module configured to determine one or more parameters of the therapy being provided to the subject;', a first breathing parameter sub-module configured to make a first preliminary determination of the breathing parameter based on the output signals in accordance with a first algorithm; and', 'a second breathing parameter sub-module configured to make a second preliminary determination of the breathing parameter based on the output signals in accordance with a second algorithm, wherein an impact of the one or more therapy parameters on the accuracy and/or precision of the first algorithm is different than an impact of the one or more therapy parameters on the accuracy and/or precision of the second algorithm; and, 'a breathing parameter module configured to determine a breathing parameter of the respiration of the subject, the breathing parameter module comprising, 'a selection module configured to select (a)(i) the first preliminary determination of the breathing parameter or (a)(ii) the second preliminary determination of the breathing parameter as a final determination of the breathing parameter (b ...

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Номер записи: 67
10-10-2013 дата публикации

SYSTEM AND METHOD FOR DETERMINING CARBON DIOXIDE EXCRETED DURING NON-INVASIVE VENTILATION

Номер: US20130267863A1
Автор: Orr Joseph Allen
Принадлежит: KONINKLIJKE PHILIPS ELECTRONICS N.V.

A system is configured to perform capnometry/capnography, and/or other compositional analysis on a non-invasively ventilated subject. As such, the system determines amounts of a molecular species of gas (e.g., carbon dioxide, oxygen, etc.) excreted by the subject on a per-breath basis. Determinations of amounts of the molecular species of gas excreted are adjusted to reflect amounts of the molecular species of gas leaked from the non-invasive interface used to communicate with the airway of the subject. 1. A system configured to determine a volume of carbon dioxide excreted by a subject during respiration , the system comprising:one or more gas parameter sensors configured to generate first output signals conveying information related to pressure and/or flow in a respiratory circuit, wherein the respiratory circuit comprises a non-invasive subject interface appliance configured to non-invasively communicate with an airway of a subject;a carbon dioxide sensor configured to generate second output signals conveying information related to a concentration of carbon dioxide present in the respiratory circuit; a concentration module configured to determine the concentration of carbon dioxide in gas expired from the airway of the subject during expiration based on the second output signals generated by the carbon dioxide sensor;', 'a leak module configured to estimate gas leakage from the respiratory circuit during respiration based on the first output signals generated by the one or more gas parameters sensors; and', 'a carbon dioxide volume module configured to determine volumes of carbon dioxide excreted by the subject during individual breaths based on (i) a determination of the concentration of carbon dioxide by the concentration module, (ii) an estimate of gas leakage from the respiratory circuit by the leak module, and (iii) the first output signals generated by the one or more gas parameters sensors and the second output signals generated by the carbon dioxide ...

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Номер записи: 68
17-10-2013 дата публикации

CARDIAC CATHETER EMPLOYING CONFORMAL ELECTRONICS FOR MAPPING

Номер: US20130274562A1
Автор: Elolampi Brian, Ghaffari Roozbeh, Lee Stephen P.
Принадлежит:

An apparatus for medical diagnosis and/or treatment is provided. The apparatus includes a flexible substrate, an intermediate bus disposed on the flexible substrate, and a plurality of sensing elements disposed on the flexible substrate and coupled to the intermediate bus. The plurality of sensing elements and intermediate bus are disposed on the flexible substrate such that the sensing elements are disposed at areas of minimal strain of the flexible substrate. 1. An apparatus for medical diagnosis and/or treatment , the apparatus comprising:a flexible substrate;at least one intermediate bus disposed on the flexible substrate; and 'wherein each sensing element of the plurality of sensing elements is coupled to the at least one intermediate bus.', 'a plurality of sensing elements disposed in a close-packed array proximate to an end of the at least one intermediate bus,'}2. The apparatus of claim 1 , wherein the sensing elements are disposed at areas of minimal bending and/or flexing of the flexible substrate.3. The apparatus of claim 1 , wherein the flexible substrate is an adhesive patch or a bandage.4. The apparatus of claim 1 , wherein a measurement of the plurality of sensing elements provides a measure of an amount of contact between the inflatable body and a surface.5. The apparatus of claim 4 , wherein the surface is a portion of a tissue claim 4 , wherein a measurement from the plurality of sensing elements provides an indication of an arrhythmia condition of the tissue.6. The apparatus of claim 4 , wherein the surface is a portion of a tissue claim 4 , wherein a measurement from the plurality of sensing elements provides an indication of an artial fibrillation or a ventricular fibrillation of the tissue.7. The apparatus of claim 1 , wherein the flexible substrate forms an inflatable body claim 1 , and wherein a portion of the at least one intermediate bus is disposed about a distal region of the inflatable body.8. The apparatus of claim 7 , wherein the ...

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Номер записи: 69
17-10-2013 дата публикации

APPARATUS AND METHOD FOR PREDICTION OF RAPID SYMPTOMATIC BLOOD PRESSURE DECREASE

Номер: US20130274570A9
Автор: Olde Bo, Solem Kristian
Принадлежит: GAMBRO LUNDIA AB

A monitoring arrangement is configured to predict a rapid syruptomatic drop in a subject's blood pressure, e.g. during a medical treatment or when operating aircraft. To this aim, a pulse shape parameter (p) with respect to a peripheral body part () of the subject (P) is repeatedly registered by means of a pulse oximetry instrument () adapted to detect light response variations in blood vessels. A respective pulse magnitude measure is calculated based on each of a number of received pulse shape parameters (p), and a statistical dispersion measure is calculated based on the thus-calculated pulse magnitude measure. It is investigated whether or not the statistical dispersion measure fulfils a decision criterion relative to a reference measure. An output signal (α) is generated if the decision criterion is found to be fulfilled. 1. A monitoring arrangement for predicting rapid symptomatic blood pressure decrease in a subject , the arrangement comprising:a pulse recording apparatus configured to repeatedly register a pulse shape parameter in a peripheral body part of the subject, wherein the pulse recording apparatus comprises a pulse oximetry instrument configured to register the pulse shape parameter based on light response variations in at least one blood vessel of the subject, anda control unit configured to receive the pulse shape parameter, the control unit comprising a processing unit configured to:calculate, during a measurement period, a respective pulse magnitude measure based on each of a number of received pulse shape parameters,calculate a statistical dispersion measure from the pulse magnitude measures,investigate whether the statistical dispersion measure fulfils a decision criterion relative to a reference measure, andgenerate an output signal indicating a prediction of said rapid symptomatic blood pressure decrease in the subject.2. The arrangement according to claim 1 , wherein the statistical dispersion measure is any of variance claim 1 , standard ...

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Номер записи: 70
17-10-2013 дата публикации

DUAL-MODE STEREO IMAGING SYSTEM FOR TRACKING AND CONTROL IN SURGICAL AND INTERVENTIONAL PROCEDURES

Номер: US20130274596A1
Автор: AZIZIAN Mahdi, Kim Peter C.W., Krieger Axel, Leonard Simon, Shademan Azad
Принадлежит: Children's National Medical Center

System and method for tracking and control in medical procedures. The system including a device that deploys fluorescent material on at least one of an organ under surgery and a surgical tool, a visual light source, a fluorescent light source corresponding to an excitation wavelength of the fluorescent material, an image acquisition and control element that controls the visual light source and the fluorescent light source, and captures and digitizes at least one of resulting visual images and fluorescent images, and an image-based tracking module that applies image processing to the visual and fluorescent images, the image processing detecting fluorescent markers on at least one of the organ and the surgical tool. 1. A system for tracking and control in medical procedures , the system comprising:a device configured to deploy fluorescent material on at least one of an organ under surgery and a surgical tool;a visual light source;a fluorescent light source corresponding to an excitation wavelength of the fluorescent material;an image acquisition and control element configured to control the visual light source and the fluorescent light source, and configured to capture and digitize at least one of resulting visual images and fluorescent images; andan image-based tracking module configured to apply image processing to the visual and fluorescent images, the image processing detecting fluorescent markers on at least one of the organ and the surgical tool.2. The system of claim 1 , further comprising:a surgical robot; anda visual servoing control module configured to receive tracking information from the image-based tracking module and to control the surgical robot, based on the tracking information, to perform a surgical operation.3. The system of claim 2 , further comprising:a manual control module configured to enable manual control of the surgical robot in place of control by the visual servoing control module.4. The system of claim 2 , wherein the visual servoing ...

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Номер записи: 71
17-10-2013 дата публикации

Haptic system for balloon tipped catheter interventions

Номер: US20130274712A1
Автор: Stuart O. Schecter
Принадлежит: Individual

Embodiments of this invention include hand-held handles and systems for balloon-tipped catheter interventions that enable a user to appreciate a combination of palpable sensations as though his or her hand is actual anatomic tissue in situ in real time. The system may include a haptic handle coupled to the proximal end of the catheter where the haptic handle includes a balloon-shaped haptic interface that exhibits geometric characteristics reflecting an anatomy of the interventional balloon and provides tangible sensations representative of tissues surrounding the interventional balloon. Multiple sensors and actuators may be used to create a non-virtual, transparent experience communicated to a user with a three dimensional, volumetric haptic display. In one embodiment, the sensors are positioned about or within an inflatable balloon positioned at the distal aspect of an inserted catheter used to treat cardiac and vascular diseases such as coronary or peripheral vascular occlusion and ablation of cardiac tissue.

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Номер записи: 72
24-10-2013 дата публикации

DEVICE WITH EXTERNAL PRESSURE SENSORS FOR ENHANCING PATIENT CARE AND METHODS OF USING SAME

Номер: US20130281885A1
Автор: Reynolds James Dixon, Rowbottom James R.
Принадлежит:

A method for monitoring physiologic conditions of a patient includes inserting an esophageal or other suitable tube into the patient, the tube comprising a lumen having a proximal end, a distal end, and central portion, and a pressure sensor disposed about at least a portion of an outer surface of the lumen of the tube. The pressure sensor is capable of detecting a change in pressure when a force is exerted against the outer surface of the lumen. The tube is then positioned within the patient and an initial pressure reading of the pressure exerted against the pressure sensors disposed about the at least a portion of the outer surface of the lumen of the tube is taken. The method also includes monitoring changes in the initial pressure reading and, if needed, taking a second pressure reading. 1. A system for monitoring physiologic conditions of a patient , comprising:a medical device having an outer surface; anda pressure sensor disposed about at least a portion of the outer surface of the medical device; wherein the pressure sensor is capable of detecting a change in pressure when a force is exerted against the outer surface of the medical device.2. The system of claim 1 , wherein the medical device is selected from the group comprising an endotracheal tube claim 1 , an esophageal feeding tube claim 1 , a catheter claim 1 , or a dermal pad.3. The system of claim 2 , wherein the medical device is an endotracheal tube.4. The system of claim 3 , wherein the endotracheal tube comprises a lumen claim 3 , the lumen having a distal end claim 3 , a central portion claim 3 , and a proximal end.5. The system of claim 4 , wherein the medical device further comprises an inflatable cuff disposed between the central portion of the lumen and the distal end of the lumen.6. The system of claim 4 , wherein the pressure sensor is disposed on the outer surface of the central portion of the lumen.7. The system of claim 4 , wherein the pressure sensor is disposed on the outer surface of ...

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Номер записи: 73
31-10-2013 дата публикации

VISUALIZING TISSUE ACTIVATED BY ELECTRICAL STIMULATION

Номер: US20130289380A1
Автор: Lazarewicz Maciej T., Molnar Gabriela C.
Принадлежит: Medtronic, Inc.

A visualization of an area or volume of tissue activated during stimulation according to a set of stimulation parameters is generated. The area or volume of activation is modeled based on a non-uniform grid of model neurons. Select portions of the grid have the model neurons more closely spaced, resulting in finer resolution graphical representation, while less closely spaced model neurons in other portions of the grid may avoid additional computation time. 1. A method comprising:defining, using at least one processor, an electrical field solution within a preselected medium, the electrical field solution defined based on a configuration of at least one electrode;generating a first grid of neuron representatives in association with the at least one electrode;determining an activation threshold value for each of the neuron representatives within the first grid of neuron representatives;based on the activation threshold values for pairs of adjacent neuron representatives, adding additional neuron representatives between at least some of the pairs of adjacent neuron representatives; andgenerating a second grid of neuron representatives comprising the first grid of representatives, and the additional neuron representatives.2. The method of claim 1 , wherein adding additional neuron representatives between at least some pairs of adjacent neuron representatives comprises adding an additional neuron representative for each pair of adjacent neuron representatives for which a first neuron representative of the pair has an activation threshold value below a predetermined value and a difference between the activation threshold value of the first neuron representative and an activation threshold value of a second neuron representative of the pair is at least some predetermined amount greater than the predetermined value.3. The method of claim 2 , further comprising:determining an activation threshold value for each additional neuron representative, wherein the additional neuron ...

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Номер записи: 74
31-10-2013 дата публикации

Bladder Fullness Level Indication Based on Bladder Oscillation Frequency

Номер: US20130289446A1
Автор: Miesel Keith A., Stone Richard T.
Принадлежит: Medtronic, Inc.

A bladder fullness level of a patient may be determined based on a frequency of mechanical oscillations of the bladder of the patient. The bladder may mechanically oscillate in response to the occurrence of non-micturition contractions of the bladder of the patient, which are contractions not associated with urine release. The frequency at which the bladder oscillates, e.g., following a non-micturition contraction, may have a correlation to the bladder fullness level. In some examples, a medical device may be configured to control the delivery of electrical stimulation therapy to the patient based on the oscillation frequency of the bladder. In addition, or instead to controlling therapy based on the oscillation frequency of the bladder, a notification, such as a patient or patient caretaker notification, may be generated (e.g., automatically by a processor of a device) based on the oscillation frequency of the bladder. 1. A system comprising:a sensor configured to generate a signal indicative of mechanical oscillation of a bladder of a patient; anda processor configured to receive the signal from the sensor, determine an oscillation frequency of the bladder based on the signal, and take a responsive action based on the oscillation frequency.2. The system of claim 1 , wherein the processor configured to compare the oscillation frequency to a threshold value claim 1 , and take the responsive action in response to determining the oscillation frequency is less than or equal to the threshold value.3. The system of claim 1 , further comprising a memory that associates a plurality of oscillation frequencies with respective responsive actions claim 1 , wherein the processor is configured to determine the responsive action associated with the oscillation frequency in the memory.4. The system of claim 1 , further comprising a medical device configured to deliver therapy to the patient claim 1 , wherein the processor is configured to take the responsive action by at least ...

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Номер записи: 75
21-11-2013 дата публикации

PHYSIOLOGICAL CONDITION DETERMINATION BASED ON PRESSURE WAVE PRODUCED BY AN IMPLANTABLE MEDICAL DEVICE HOUSING

Номер: US20130310706A1
Автор: Stone Richard T., Wei Xuan
Принадлежит: Medtronic, Inc.

A physiological state of a patient is detected by at least producing and detecting pressure waves with a free wall of an implantable medical device (IMD) housing. An actuator element may contact the free wall, e.g., a portion of the IMD housing, and cause movement of the free wall that produces a pressure wave within the fluid and tissue of the patient. A detector element contacting the free wall may in turn detect reflected pressure waves received by the free wall. An acoustic module within the IMD may then determine a physiological condition of the patient, e.g., a bladder fullness state, based on the time delay between the transmitted and reflected pressure waves. In some examples in which the IMD also delivers stimulation therapy to the patient, e.g., incontinence therapy, the IMD may also automatically adjust stimulation therapy based on the determined physiological condition. 112-. (canceled)13. A method comprising:producing a pressure wave within a patient with a portion of a housing of an implantable medical device, wherein the housing substantially encloses a processor;detecting at least one reflected pressure wave with the housing portion; anddetermining, by the processor and based on the at least one reflected pressure wave, a physiological condition of the patient.14. The method of claim 13 , wherein the portion of the housing is configured to enclose operational circuitry of the implantable medical device claim 13 , and wherein the portion of the housing is tuned to one or more frequencies of the pressure wave.15. The method of claim 13 , wherein producing the pressure wave further comprises:producing the pressure wave from an internal location inferior to a bladder and lateral to a labia; anddirecting the pressure wave towards the bladder.16. The method of claim 13 , wherein the physiological condition includes a bladder fullness state.17. The method of claim 13 , wherein determining the physiological condition further comprises:determining a time ...

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Номер записи: 76
28-11-2013 дата публикации

ELECTROMAGNETIC APPARATUS AND METHOD FOR NERVE LOCALIZATION DURING SPINAL SURGERY

Номер: US20130317340A1
Автор: II Erich, Wolf
Принадлежит:

An electromagnetic pedicle awl utilizes a tightly focused time-varying magnetic flux to create a localized electromotive force (EMF) near the tip. The localized EMF creates localized eddy currents in nearby nerves which excite ionic nerve channels, the excitation being detected by an electromyographic recording device. The awl only excites nerves directly in front of and directly to the side of the tip. The awl is comprised of a tapered awl or drill tip in combination with a solid core surrounded by a solenoid. A pulsed electric current source drives the solenoid to create a time-varying magnetic field in the vicinity of the tapered tip. The awl or drill tip may be stationary with respect to the solenoid or it may rotate. The awl in combination with an EMG detector connected to a patient is sensitive to the pedicle hole position with respect to adjacent nerves and reduces false placement failure. 1. A surgical awl tool for creating a pilot hole in muscle material proximate to a set of nerve fibers , the tool capable of producing magnetic fields comprised of:a solid core bushing;a tapered drill, having a drill tip and a cylindrical shaft, the cylindrical shaft resident in the solid core bushing so that a portion of the cylindrical shaft protrudes axially from the solid core bushing;the cylindrical shaft having a reverse thrust bearing attached near the tapered drill and set against the solid core bushing;the cylindrical shaft having a forward thrust bearing attached to the cylindrical shaft and set against the end of the solid core bushing so as not to allow lateral movement of the tapered drill with respect to the solid core bushing;a solenoid assembly for producing a magnetic field further comprised of a conductive coil of wire around the solid core bushing;an electric current source attached to the conductive coil of wire so that a time varying magnetic field is generated in the vicinity of the drill tip; and,a mechanism for detecting the excitation of the set of ...

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Номер записи: 77
28-11-2013 дата публикации

Integration of MRI into Radiation Therapy Treatment

Номер: US20130317343A1
Автор: Dahan Meir, Guyot Brendan, Hornblower Victoria, Klimenko Gordon, Petropoulos Labros, Saunders John, VAN HETEREN John, Winter Jeff, Yi Hongxiang
Принадлежит:

Apparatus for radiation therapy combines a patient table, an MRI and a radiation treatment apparatus mounted in a common treatment room with the MR magnet movable from a position outside a radiation shielded door to an imaging position. An RF-shielded door is movable between a position, separating part of the treatment apparatus from the magnet and an open position allowing access of the patient to the treatment apparatus. In one configuration there is a row of treatment rooms and the magnet is mounted to move along a passageway outside the row of radiation shielded doors of the rooms. 1. Apparatus for radiation therapy of a patient comprising:a patient support table;a patient support table;a magnetic resonance imaging system for acquiring MR images of an imaging volume including the target location of the patient; an MR magnet operable to generate a magnetic field to be applied to the patient, the magnet having a cylindrical bore for surrounding the target location of the patient;', 'an RF transmit coil arrangement for generating an RF pulse in a transmit stage to be applied to the subject to be imaged such that the subject generates an MR signal in response to the magnetic field and the RF pulse applied;', 'a receive coil arrangement for acquiring the MR signal in a receive stage;', 'and a signal processing system for receiving the MR signal for carrying out signal processing by which an image is generated;, 'the imaging system includinga treatment apparatus for applying a radiation therapy to a target location in the patient on the support table;the patient support table and the treatment apparatus being mounted in a treatment room which is radiation shielded and has an opening which includes a radiation shielded door arrangement operable to close the opening;the MR magnet being mounted for movement from a position exterior of the radiation shielded door arrangement into the opening to an imaging position for cooperation with the patient on the patient support ...

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Номер записи: 78
28-11-2013 дата публикации

SYSTEM AND METHOD FOR ADVANCING, ORIENTING, AND IMMOBILIZING ON INTERNAL BODY TISSUE A CATHETER OR OTHER THERAPEUTIC DEVICE

Номер: US20130317385A1
Автор: Ring Howard, Sklar Martin J.
Принадлежит:

This invention provides a system and method that allows a therapeutic device, such as an atrial fibrillation microwave ablation catheter or ablation tip to be guided to a remote location within a body cavity and then accurately immobilized on the tissue, including that of a moving organ, such as the heart. 134-. (canceled)35. An ablation device , the device comprising:an ablation catheter comprising an ablation element; andan immobilizer mechanism coupled to the ablation catheter, wherein the immobilizer mechanism is configured to anchor the catheter and to allow axial movement of the ablation element while the immobilizer mechanism is engaged.36. The device according to claim 35 , wherein the ablation catheter is a radiofrequency ablation catheter.37. The device according to claim 35 , wherein the device is steerable.38. The device according to claim 35 , wherein the immobilizer mechanism comprises an electrical conductivity sensor.39. The device according to claim 38 , wherein the electrical conductivity sensor can verify that a therapeutic ablation has been delivered.40. The device according to claim 35 , further comprising a locking mechanism that is configured to lock the ablation catheter axially in place.41. The device according to claim 35 , further comprising a control system operably coupled to the device.42. The device according to claim 41 , wherein the control system controls an amount of energy transmitted to the ablation catheter.43. A method for ablating a target tissue in a patient's body claim 41 , the method comprising:providing a device comprising an ablation catheter comprising an ablation element; andan immobilizer mechanism coupled to the ablation catheter, wherein the immobilizer mechanism is configured to anchor the catheter and to allow axial movement of the ablation element while the immobilizer mechanism is engaged;inserting the device into a patient's bodyimmobilizing the device within the patient's body;axially moving the ablation ...

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Номер записи: 79
28-11-2013 дата публикации

VALVE APERTURE SIZING DEVICES AND METHODS

Номер: US20130317392A1
Автор: Kassab Ghassan S.
Принадлежит: DTherapeutics, LLC

Valve aperture sizing devices and methods. In an exemplary method to size a valve aperture, the method comprises introducing at least part of a first device into a luminal organ at a valve aperture, the first device having a balloon positioned thereon, inflating the balloon within the valve aperture until a point of apposition is achieved, and obtaining a first valve aperture measurement based upon the point of apposition. 1. A method to size a valve aperture , comprising:introducing at least part of a first device into a luminal organ at a valve aperture, the first device having a balloon positioned thereon;inflating the balloon within the valve aperture until a point of apposition is achieved; andobtaining a first valve aperture measurement based upon the point of apposition.2. The method of claim 1 , further comprising:selecting a stent valve based upon the first valve aperture measurement.3. The method of claim 2 , further comprising:positioning the stent valve upon the balloon;re-introducing the at least part of the first device into the luminal organ; andre-inflating the balloon to place the stent valve within the luminal organ.4. The method of claim 3 , wherein the step of re-introducing is performed to re-introduce the at least part of the first device into the luminal organ at or near the valve aperture claim 3 , and wherein the step of re-inflating is performed to place the stent valve within the luminal organ at or near the valve aperture.5. The method of claim 3 , further comprising:positioning the stent valve around at least part of a second device;introducing the at least part of the second device into the luminal organ; andpositioning the stent valve within the luminal organ using the second device.6. The method of claim 1 , wherein the first device is configured as a catheter having a lumen therethrough and defining a suction/infusion port so that the lumen is in communication with the balloon claim 1 , and wherein the step of inflating is performed ...

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Номер записи: 80
28-11-2013 дата публикации

PRESSURE SENSOR ASSEMBLY AND ASSOCIATED METHOD FOR PREVENTING THE DEVELOPMENT OF PRESSURE INJURIES

Номер: US20130317393A1
Автор: Assouline Yonatan, Averbuch Gusti, Ben David Boaz, BEN SHALOM AMIR, Greenstein Lior, Poliakine-Baruchi Ruth, Raab Itai, Remez Tal, Weiss Dan, Zaritzky Efrat
Принадлежит: ENHANCED SURFACE DYNAMICS, INC.

A pressure wound prevention system comprising at least one management device which comprises at least one user input apparatus, at least one output mechanism, at least one data input for connecting with a pressure sensor assembly and a processor configured to measure elapsed time, to receive pressure data from the data input and to present an output via the output mechanism. The system may be modular. A method for preventing the development of pressure wounds of a subject is also presented. 160-. (canceled)61. A pressure wound prevention system comprising:at least one sensor module comprising a plurality of pressure sensor elements; and at least one user input apparatus;', 'at least one output mechanism;', 'at least one data input connectable with the at least one sensor module; and', 'a processor configured to measure elapsed time, to receive pressure data from the data input, use the pressure data to calculate at least one risk index, compare the calculated risk index with at least one threshold value and to present an output via the output mechanism when the calculated risk index is greater than the at least one threshold value., 'at least one management module connectable with the sensor module, the at least one management module including62. The pressure wound prevention system of wherein the at least one sensor module comprises a docking station configured to connect to the at least one management module.63. The pressure wound prevention system of wherein the docking station includes a wireless communicator configured to communicate pressure data to the at least one management module.64. The pressure wound prevention system of wherein the at least one sensor module and the at least one management module each include at least one set of electrical contacts configured to connect with a corresponding set of electrical contacts on the other of the at least one sensor module and the at least one management module.65. The pressure wound prevention system of wherein ...

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Номер записи: 81
05-12-2013 дата публикации

Treating Heart Tissue

Номер: US20130323709A1
Автор: Mohl Werner
Принадлежит: MIRACOR MEDICAL SYSTEMS GMBH

Some embodiments of a system or method for treating heart tissue can include a catheter device that provides a user with the ability to perform a number of heart treatment tasks (before, during, and after a cardiac surgery or a percutaneous coronary intervention). In particular embodiments, the catheter device can be used to (i) precondition heart muscle tissue before the heart is isolated from the circulatory system, (ii) deliver cardioplegia into the coronary sinus during the cardiac surgery when the heart is isolated from the circulatory system, and (iii) control the blood flow through the heart after the heart is reconnected with the circulatory system. In some embodiments, the catheter device can perform some or all of: (i) intermittently occluding the coronary sinus, (ii) delivering a treatment fluid into the coronary sinus, and (iii) monitoring a flow rate of blood passing from the coronary sinus to the right atrium. 1. (canceled)2. A method of using a coronary sinus occlusion catheter , comprising:engaging an inflatable balloon device of a distal tip portion of the coronary sinus occlusion catheter with an interior wall of the coronary sinus while the inflatable balloon device is in an inflated condition,detecting a first pressure at a first pressure sensor lumen that extends to a distal position that is distal of the inflatable balloon device;detecting a second pressure at a second pressure sensor lumen that extends to a proximal position that is proximal of the inflatable balloon device for detecting a second pressure; anddetermining a blood flow rate of blood passing along the distal tip portion in the coronary sinus from a region distal of the balloon device to a region proximal of the balloon device by comparing the first pressure detected at the first pressure sensor lumen and the second pressure detected at the second pressure sensor lumen.3. The method of claim 2 , further comprising intermittently adjusting the inflatable balloon device between a ...

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Номер записи: 82
05-12-2013 дата публикации

INTERFACE UNIT AND A MEASUREMENT SYSTEM

Номер: US20130324806A1
Автор: SAMUELSSON Magnus
Принадлежит:

The present invention relates to an extracorporeale interface unit (), for an intravascular measurement system for measuring at least one physiological, or other, variable in a living body, adapted to generate a sensor signal in response of the variable. The interface unit () comprises a sensor interface circuitry () adapted to interface a sensor wire configured to be inserted into the living body and provided with one or many sensor element (s) at its distal region. The sensor interface circuitry () comprises a measurement unit () adapted to generate the measured data of the variable as a sensor signal. The interface unit () further comprises a control unit () adapted to control and supervise the different functions of the interface unit (), wherein the different functions are performed by predefined tasks (T, T . . . TN) during consecutive control periods CP having the same time duration. 116-. (canceled)17. An extracorporcale interface unit , for an intravascular measurement system for measuring at least one physiological , or other , variable in a living body , adapted to generate a sensor signal in response of said variable , which interface unit comprises:a sensor interface circuitry adapted to interface a sensor wire configured to be inserted into the living body and provided with one or many sensor element(s) at its distal region, the sensor interface circuitry comprises a measurement unit adapted to generate said measured data of said variable as a sensor signal;{'sub': 1', '2', 'n', 'cp', '1', '2', 'n, 'a control unit adapted to control and supervise the different functions of the interface unit, wherein the different functions are performed by predefined tasks (T, T. . . T) during consecutive control periods CP having the same time duration t, and that during each task (T, T. . . T) a predefined function of the interface unit is performed,'}{'sub': 1', '2', 'n', '1', '2', '3', 'n', '1', '2', 'n', '1', '2', 'n', '1', '2', 'n', 's, 'wherein each predefined ...

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Номер записи: 83
05-12-2013 дата публикации

Device for diagnosing condition of liver and method of examining condition of liver

Номер: US20130324821A1
Автор: Akifumi Nakagawa, Toshio Kokuryo, Yukihiro Yokoyama
Принадлежит: Nagoya University NUC

The diagnostic device disclosed in this application is a device for diagnosing liver condition. The diagnostic device comprises a nitric oxide sensor and an information output unit. The nitric oxide sensor can be brought into contact with hepatocytes making up the liver and detects the concentration of nitric oxide produced by the hepatocytes. The information output unit, based on the nitric oxide concentration detected by the nitric oxide sensor, outputs information for diagnosing the condition of the liver. The information output unit can, for example, output a graph showing the change over time in the nitric oxide concentration detected by the nitric oxide sensor.

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Номер записи: 84
05-12-2013 дата публикации

Robotic surgical system and method for automated therapy delivery

Номер: US20130325035A1
Автор: Jeffrey A. Schweitzer, John A. Hauck, Kedar Ravindra Belhe
Принадлежит: St Jude Medical Atrial Fibrillation Division Inc

A method of navigating a medical device through a body of a patient includes providing a topography of at least a portion of the body, accepting user input defining a navigation path, robotically navigating the medical device to a starting point on the path, and robotically navigating the medical device along the navigation path to an endpoint. Waypoints defining the navigation path may be input on a graphical representation of the topography using a user interface such as a pointing device or touchscreen. The navigation path may also be defined by tracing a substantially continuous path on the graphical representation. A therapy may be administered while robotically navigating the medical device along the navigation path, either forward or in reverse, or while navigating the medical device along a return path defined by a plurality of virtual breadcrumbs generated as the medical device traverses the navigation path.

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Номер записи: 85
12-12-2013 дата публикации

Sleep surface insert system and method thereof

Номер: US20130326811A1
Автор: Dana L. Miles, Scott D. Miles
Принадлежит: Individual

A sleep surface insert system and method for positioning under, for example, an infant on a sleep surface. The sleep surface insert system includes an insert and a blower system. The insert includes a top liner and a bottom liner. The top liner and bottom liner define first and a second hollow spaces therebetween. Further, the top liner includes first and second pores such that the first pores extend through the top liner from the first hollow space and the second pores extend through the top liner from the second hollow space. In addition, the blower system is configured to provide air flow into the first and second hollow spaces defined in the insert such that the air flow is configured to flow into the insert and out of at least one of the first pores and the second pores.

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Номер записи: 86
12-12-2013 дата публикации

NEURONAVIGATION-GUIDED FOCUSED ULTRASOUND SYSTEM AND METHOD THEREOF

Номер: US20130331685A1
Автор: LIU Hao-Li, LU Yu-Jen, TSAI Hong-Chieh, WEI Kuo-Chen
Принадлежит: CHANG GUNG UNIVERSITY

The present invention discloses a neuronavigation-guided focused ultrasound system and a method for the same, which are used to guide focused ultrasound energy to a target point. The system of the present invention comprises a focused ultrasound device, a neuronavigation system and a fixture. According to an image of an interested region of an individual, a focus point of the focused ultrasound device, and tracking points provided by the neuronavigation system, the neuronavigation system performs a calibration process and establishes a positional relationship between the focus point and the image of the interested region. Thereby, the neuronavigation system can recognize the focus point and guide focused ultrasound to the target point. 1. A neuronavigation-guided focused ultrasound system , which guides a focused ultrasound energy to a target point , comprisinga focused ultrasound device generating a focus point and delivering said energy to said target point;a neuronavigation system electrically connecting with said focused ultrasound device and including a calibration unit, wherein said calibration unit establishes a positional relationship between said focus point and an image of a interested region of an individual, performs a calibration process on coordinates, and enables said neuronavigation system to recognize said focus point and define said target point; anda fixture fixing said interested region of said individual.2. The neuronavigation-guided focused ultrasound system according to claim 1 , wherein said focused ultrasound device further comprisesa signal generator generating an ultrasonic signal;a signal amplifier electrically connecting with said signal generator and amplifying said ultrasonic signal into said focused ultrasound; andan ultrasonic transducer electrically connecting with said signal amplifier, delivering said focused ultrasound to said target point, wherein a central frequency of said focused ultrasound resonates with said ultrasonic ...

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Номер записи: 87
12-12-2013 дата публикации

METHOD FOR CALCULATING OR APPROXIMATING A VALUE REPRESENTING THE RELATIVE BLOOD VOLUME AND DEVICES

Номер: US20130331712A1
Автор: Chamney Paul, MOISSL Ulrich, Nier Volker, Wabel Peter, Wieskotten Sebastian
Принадлежит: FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH

The present invention relates to a method for calculating or approximating a value representing the relative blood volume (RBV) at a certain point of time, or a value representing the refilling volume of a patient that may be observed or found during or due to a blood treatment of the patient, the method involving considering one or more calculated or measured value(s) reflecting an overhydration level of the patient or an approximation thereof. It relates further to an apparatus and a device for carrying out the present invention, a blood treatment device, digital storage means, a computer program product, and a computer program. 123-. (canceled)24. A method for calculating or approximating or predicting a value representing the absolute blood volume (BV) or the relative blood volume (RBV) at a certain point of time or the normalized or normohydrated relative blood volume (RBV(t)) , or a value representing a refilling volume (V refill) of a patient that may be observed or found or calculated or measured during or due to a blood treatment of the patient , the method comprising the step of considering one or more calculated or measured value(s) reflecting an overhydration (OH) level or an overhydration of the patient or an approximation thereof.25. The method according to claim 24 , wherein for calculating or approximating or predicting a value representing the relative blood volume (RBV) or a value representing the refilling volume (V_refill) claim 24 , the absolute start blood volume (BV_start) upon or before beginning of the blood treatment is considered.26. The method according to claim 25 , wherein for assessing the absolute start blood volume (BV_start) at least one value reflecting the lean mass (LTM) and at least one value reflecting the fat mass (ATM) of the patient's body claim 25 , or approximations thereof claim 25 , are considered.28. The method according to claim 24 , further comprising the step of predicting an end value of the relative blood volume ( ...

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Номер записи: 88
19-12-2013 дата публикации

METHODS FOR GENERATING LUMINAL ORGAN PROFILES USING IMPEDANCE

Номер: US20130338468A1
Автор: Kassab Ghassan S.
Принадлежит:

Methods to generate luminal organ profiles using impedance. One embodiment of such a method comprises the steps of introducing an impedance device having at least two detection electrodes positioned in between at least two excitation electrodes into a treatment site of a luminal organ at a first position, measuring a first treatment site conductance at the first position using the impedance device and at least two injections of solutions having different conductivities, moving the impedance device to a second position in the luminal organ, measuring a second treatment site conductance at the second position using the impedance device and the at least two injections of solutions having different conductivities, calculating a first position cross-sectional area using the first treatment site conductance and a second position cross-sectional area using the second treatment site conductance, and constructing a profile of the treatment site. 1introducing an impedance device having at least two detection electrodes positioned in between at least two excitation electrodes into a treatment site of a luminal organ at a first position;measuring a first treatment site conductance at the first position using the impedance device and at least two injections of solutions having different conductivities;moving the impedance device to a second position in the luminal organ;measuring a second treatment site conductance at the second position using the impedance device and the at least two injections of solutions having different conductivities;calculating a first position cross-sectional area using the first treatment site conductance and a second position cross-sectional area using the second treatment site conductance; andconstructing a profile of the treatment site based in part on the calculated first cross-sectional area and the calculated second cross-sectional area.. A method of creating a cross-sectional area profile of a targeted treatment site, the method comprising the ...

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Номер записи: 89
19-12-2013 дата публикации

FUNCTIONAL ASSESSMENT AND TREATMENT CATHETERS AND METHODS FOR THEIR USE IN THE LUNG

Номер: US20130338524A1
Автор: ALJURI Nikolai, Farhnoltz Roger, Gia Son, Nair Ajit
Принадлежит: Pulmonx, Inc.

Lung conditions are diagnosed and optionally treated using a functional assessment catheter or a functional lung assessment and treatment catheter. A flow restrictive component is initially placed in a bronchus or lung passageway upstream from a diseased lung region. The isolated lung region is then functionally assessed through the catheter, while the flow restrictive component remains in place. If the patient is a good candidate for treatment by occlusive or restrictive treatment techniques, the flow resistive component may be left in place. If the patient is not suitable for such treatment, the flow resistive component may be removed. 1. A functional assessment catheter for the lungs , said catheter comprising:a catheter shaft having a distal and a proximal end, and a central passage therebetween;a flow restrictive component disposed at the distal end of the catheter shaft, wherein the flow restrictive component has an expanded configuration and a contracted configuration; andan obturator disposed in the central passage and shiftable between a distally advanced position where it engages and elongates the flow restrictive component to cause the component to assume the contracted configuration, and a proximally retracted position where it allows the flow restrictive component to shorten and return to the expanded configuration.2. A functional assessment catheter as in claim 1 , wherein the flow restrictive component comprises a resilient scaffold and an elastomeric covering.3. A functional assessment catheter as in claim 2 , wherein the resilient scaffold comprises counter wound helical supports.4. A functional assessment catheter as in claim 1 , wherein a flow path is formed through the flow restrictive component so that gas may flow through the catheter shaft and through the flow restrictive component.5. A functional assessment catheter as in claim 4 , wherein the flow path comprises the central passage and an opening in a distal side of the elastomeric covering. ...

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Номер записи: 90
19-12-2013 дата публикации

Body lumen junction localization

Номер: US20130338530A1
Автор: Ghassan S. Kassab
Принадлежит: Individual

Devices, systems, and methods for the localization of body lumen junctions and other intraluminal structure are disclosed. Various embodiments permit clinicians to identify the locations of intraluminal structures and medical devices during non-surgical medical techniques, such as cardiac ablation, by determining the intralumen conductance and/or cross-sectional area at a plurality of locations within the body lumen

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Номер записи: 91
19-12-2013 дата публикации

Systems and methods to reduce syncope risk during neural stimulation therapy

Номер: US20130338727A1
Автор: Eric A. Mokelke, Guy Alvarez, Harlan Bos, John D. Hatlestad, Kenneth Martin Stein, Shibaji Shome
Принадлежит: Cardiac Pacemakers Inc

Some embodiments, by way of example, provide a system, comprising a posture change detector configured to detect a posture transition indicative of an increased risk of syncope, and a neural stimulator configured to deliver a neural stimulation therapy. The neural stimulator may include a syncope avoidance module configured to respond to a detected posture transition by temporarily overriding the neural stimulation therapy to ameliorate the risk of increased syncope.

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Номер записи: 92
26-12-2013 дата публикации

MEDICAL VENTILATOR WITH INTEGRATED OXIMETER DATA

Номер: US20130345532A1
Автор: Doyle Peter, Graboi Dan, Sanborn Warren, Vandine Joseph Douglas
Принадлежит: COVIDIEN LP

This disclosure describes systems and methods for managing the ventilation of a patient being ventilated by a medical ventilator. The disclosure describes a novel approach of displaying ventilator information integrated with oximeter information. The disclosure further describes a novel approach of alarming based on the integration of ventilator information with oximeter information. 1. A method for managing the ventilation of a patient being ventilated by a medical ventilator , the method comprising:monitoring a patient during ventilation with an oximeter;monitoring an oxygen saturation level of blood in the patient during ventilation;monitoring a PEEP level of the patient;graphing a function of the oxygen saturation level of the blood in the patient and the PEEP level versus time; anddisplaying a graph of the function versus time on a display.2. The method of claim 1 , wherein the graph is displayed by an oximeter display.3. The method of claim 1 , wherein the graph is displayed by a ventilator display.4. The method of claim 1 , further comprising displaying at least one preset threshold on the graph.5. The method of claim 1 , further comprising:determining that the function is outside a preset threshold;determining that the PEEP level of the patient dropped prior to a drop in the oxygen saturation level of the blood in the patient; andexecuting an alarm.6. The method of claim 1 , further comprising:determining that the function is outside a preset threshold; andexecuting an alarm.7. The method of claim 1 , further comprising:determining that the function is outside a preset threshold;determining that a drop in the oxygen saturation level of the blood in the patient is independent of a change in the PEEP; andexecuting an alarm.8. The method of claim 1 , wherein the step of graphing the oxygen saturation level of the blood in the patient as a function of the PEEP level versus time comprises converting raw PEEP data and raw oxygen saturation level data into a ...

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Номер записи: 93
26-12-2013 дата публикации

ELECTROSURGICAL DEVICE INCORPORATING A PHOTO-ACOUSTIC SYSTEM FOR INTERROGATING/IMAGING TISSUE

Номер: US20130345541A1
Автор: JR. William H., Nau
Принадлежит:

The present disclosure is directed to an electrosurgical system for imaging and interrogating tissue. The electrosurgical system includes an energy source configured to generate a first energy and an electrosurgical instrument. the electrosurgical instrument includes a transmission line coupled to the energy source and configured to emit the first energy. A mirror reflects the first energy towards a target tissue that emits a second energy. An ultrasonic transducer receives the second energy from the target tissue and converts the second energy into an electrical signal. A controller receives the electrical signal and converts the electrical signal into an image. 1. An electrosurgical system , comprising:a first energy source configured to output a first energy; a housing;', 'a transmission line coupled to the first energy source and configured to emit the first energy;', 'a mirror configured to reflect the first energy towards a target tissue;', 'an ultrasonic transducer configured to receive a second energy from the target tissue and convert the second energy into an electrical signal; and, 'an electrosurgical instrument includinga controller configured to receive the electrical signal and convert the electrical signal into an image.2. The electrosurgical system according to claim 1 , wherein the electrosurgical instrument further comprises a motor coupled to the mirror and configured to translate the mirror along a longitudinal axis defined through the electrosurgical instrument.3. The electrosurgical system according to claim 1 , wherein the electrosurgical instrument further comprises a motor coupled to the mirror and configured to rotate the mirror around a longitudinal axis defined through the electrosurgical instrument.4. The electrosurgical system according to claim 1 , wherein the energy source is a laser.5. The electrosurgical system according to claim 4 , wherein the transmission line is an optical fiber.6. The electrosurgical system according to claim 1 ...

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Номер записи: 94
26-12-2013 дата публикации

Wireless catheter with base wireless transceiver

Номер: US20130345549A1
Автор: Assaf Govari
Принадлежит: Biosense Webster Israel Ltd

A medical probe, including a flexible insertion tube having a distal end for insertion into a body cavity and including one or more sensors mounted in the distal end, and a handle coupled to a proximal end of the insertion tube. The medical probe also includes a cable having a proximal end and a distal end, which is coupled to the handle so as to receive signals conveyed through the insertion tube from the one or more sensors, and a base unit coupled to the proximal end of the cable. The base unit contains a power source, and a probe wireless transceiver coupled to receive the signals from the cable and to communicate over a wireless connection with a control console.

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Номер записи: 95
02-01-2014 дата публикации

SYSTEMS AND METHODS FOR TREATING SLEEP APNEA

Номер: US20140000611A1
Автор: Mahadevan Anandi, McDermott Mark Christopher, Procyk Christopher Anthony, Truschel William A.
Принадлежит:

Sleep apnea can be treated using positive airway pressure. Methods and systems for determining a level of airway obstruction allow beneficial adjustments to the level of expiratory positive airway pressure used to treat a subject. 1. A system for treating sleep apnea of a subject having an airway by enhancing expiratory positive airway pressure , the system comprising:(a) a pressure generator configured to generate a pressurized flow of breathable gas for delivery to the airway of the subject.(b) one or more sensors configured to generate one or more output signals conveying measurements related to one or more parameters of the subject; and (1) a control module configured to control the pressure generator to adjust one or more parameters of the pressurized flow of breathable gas such that the airway of the subject is provided with a target expiratory positive airway pressure of the subject,', '(2) a resistance module configured to estimate upper airway resistance of the subject based on the one or more output signals, and', '(3) an adjustment module configured to adjust the target expiratory positive airway pressure based on the estimated upper airway resistance, wherein the adjustment module is further configured to make periodical adjustments of the target expiratory positive airway pressure, and to determine whether to reverse or accept an individual periodical adjustment based on subsequently estimated upper airway resistance., '(c) one or more processors configured to execute computer program modules, the computer program modules comprising2. The system of claim 1 , wherein the target expiratory positive airway pressure is limited to a range of available levels of expiratory positive airway pressure claim 1 , and wherein the adjustment module is configured to adjust the target expiratory positive airway pressure to correspond to the lowest upper airway resistance in the range of available levels of expiratory positive airway pressure.3. The system of claim 1 , ...

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Номер записи: 96
02-01-2014 дата публикации

CATHETER COMPRISING CAPACITIVE MICROMACHINED ULTRASONIC TRANSDUCERS WITH AN ADJUSTABLE FOCUS

Номер: US20140005521A1
Автор: Dekker Ronald, Dirksen Peter, Köhler Max Oskar, Sokka Shunmugavelu
Принадлежит: KONINKLIJKE PHILIPS ELECTRONICS N.V.

A catheter () comprising: a shaft with distal () and proximal ends (),wherein the distal end comprises at least one array of capacitive micromachined ultrasound transducers ( ) with an adjustable focus for controllably heating a target zone (); and a connector () at the proximal end for supplying the at least one array of capacitive micromachined ultrasound transducers with electrical power and for controlling the adjustable focus. 1. A catheter comprising:a shaft with distal and proximal ends, wherein the distal end comprises a transducer module with at least one array of capacitive micromachined ultrasound transducers with an adjustable focus for controllably heating a target zone; anda connector at the proximal end for supplying the at least one array of capacitive micromachined ultrasound transducers with electrical power and for controlling the adjustable focus wherein the transducer module is at least partly flexible.2. The catheter as claimed in claim 1 , wherein the at least one array of capacitive micromachined ultrasound transducers is disposed on a flexible material.3. The catheter of claim 1 , wherein the transducer module comprises at least two arrays of capacitive micromachined ultrasound transducers claim 1 , and wherein the catheter further comprises a flexible element between the at least two capacitive micro machined transducers.4. The catheter of claim 2 , wherein the catheter further comprises a mechanical actuator for at least partially adjusting the adjustable focus by deforming the transducer module.5. The catheter of claim 1 , wherein the distal end has a length extension claim 1 , and wherein at least a portion of at least one array of capacitive micromachined ultrasound transducers is orientated such that the target zone is located adjacent to the length extension.6. The catheter of claim 5 , wherein at least some of the at least one array of capacitive micromachined ultrasound transducers form a ring around the shaft and orientated along a ...

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Номер записи: 97
02-01-2014 дата публикации

DEVICES AND METHODS FOR PREDICTING AND PREVENTING RESTENOSIS

Номер: US20140005534A1
Автор: BLACK John F., HE Xuanmin, ROSENTHAL Michael H., Simpson John B.
Принадлежит:

The present invention relates to methods and devices for predicting restenosis, and for treating atherosclerosis to prevent or reduce the incidence of restenosis. Methods of predicting restenosis in a stenosed peripheral artery may include quantitative histology of the vessel. For example, a method of treating a stenosed artery (and particularly a peripheral artery) may include the steps of determining a level of hypercellularity and one or more of the lipid-richness and extent of inflammatory cell inclusion in the tissue. An index of restenosis based on the hypercellularity and lipid richness and/or extent of inflammatory cell inclusion in the tissue may be determined. Systems for treating or preventing restenosis may include one or more imaging modalities for imaging tissue regions and determining the level of hypercellularity and one or more of the degree of lipid-richness and the extent of inflammatory cell inclusion in the tissue region. 1. A device for treating atherosclerosis and prevent restenosis , the device comprising:an imaging catheter having a sensor configured to image a portion of an artery;a processor configured to receive images of the artery from the sensor processor and to detect regions of hypercellularity in the artery based on the received images, and further configured to detect regions of either or both: lipid-rich tissue and inflammatory cells in the artery from the received images; anda display configured to display a modified view of the artery indicating hypercellularity and one or both of lipid-rich tissue and inflammatory cells in the artery.2. The device of claim 1 , wherein the imaging catheter is an atherectomy catheter.3. The device of claim 1 , wherein the imaging catheter is an OCT imaging catheter and the sensor comprises an OCT imaging sensor.4. The device of claim 1 , wherein the processor and display are configured to operate in real or near-real time.5. The device of claim 1 , wherein the processor comprises detection logic ...

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Номер записи: 98
02-01-2014 дата публикации

MULTI-SEGMENTED INFLATABLE BRACHYTHERAPY DEVICES, SYSTEMS, AND METHODS OF USING THE SAME

Номер: US20140005539A1
Автор: Biagioli Matthew C., Forster Kenneth M.
Принадлежит: H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE INC

Provided are multi-segmented inflatable brachytherapy devices. Also provided are systems and methods including multi-segmented inflatable brachytherapy devices. 1. A sleeve for positioning on a brachytherapy applicator , comprising:(a) a first inflatable segment having a primary lumen;(b) a second inflatable segment having a primary lumen; and(c) wherein the first and second segments are selectively inflatable by delivery of fluid into each lumen.2. The sleeve of claim 1 , wherein the sleeve defines a central passage configured for positioning over the brachytherapy applicator.3. The sleeve of claim 2 , wherein the brachytherapy applicator comprises a distal ring.4. The sleeve of claim 3 , wherein the sleeve has a proximal and distal end and wherein the distal end is configured for positioning proximal to the distal ring of the brachytherapy applicator.5. The sleeve of claim 1 , further comprising at least one conduit configured for delivering fluid into the primary lumen of the first segment.6. The sleeve of claims 5 , further comprising at least one conduit configured for delivering fluid into the primary lumen of the second segment.7. The sleeve of claim 5 , wherein the first inflatable segment further comprises:(a) a second lumen located at least partially within the primary lumen of the first segment; and(b) at least one conduit in fluid communication with the second lumen, wherein the second lumen is configured to accept fluid delivered through the at least one conduit.8. The sleeve of claim 6 , wherein the second inflatable segment further comprises:(a) a second lumen located at least partially within the primary lumen of the second segment; and(b) at least one conduit in fluid communication with the second lumen, wherein the second lumen is configured to accept fluid delivered through the at least one conduit.9. The sleeve of claim 8 , wherein each inflatable segment comprises more than two lumens.10. The sleeve of claim 7 , wherein the fluid accepted into ...

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Номер записи: 99
02-01-2014 дата публикации

SYSTEMS AND METHODS FOR ANALYSIS AND TREATMENT OF A BODY LUMEN

Номер: US20140005553A1
Автор: Gambale Richard, Ryan S. Eric, Tang Jing
Принадлежит: CorNova, Inc.

A system is provided for probing a body lumen that includes a flexible conduit that is elongated along a longitudinal axis, the flexible conduit having a proximal end and a distal end, at least one delivery waveguide and at least one collection waveguide extending along the flexible conduit, a transmission output of the at least one delivery waveguide and a transmission input of the at least one collection waveguide located along a distal portion of the conduit. A spectrometer is connected to the at least one delivery waveguide and the at least one collection waveguide, the spectrometer configured to perform spectroscopy. A controller system is configured to calculate a distance between the flexible conduit and the wall of the body lumen based on a spectroscopic measurement of the at least one primary radiation signal that traveled between the flexible conduit and body lumen. 1. A system for analyzing a body lumen comprising:a catheter comprising a flexible conduit that is elongated along a longitudinal axis, the flexible conduit having a proximal end and a distal end;at least one delivery waveguide and at least one collection waveguide extending along the flexible conduit, a transmission output of the at least one delivery waveguide and a transmission input of the at least one collection waveguide located along a distal portion of the conduit;a spectrometer connected to the at least one delivery waveguide and the at least one collection waveguide, the spectrometer configured to perform diffuse reflectance spectroscopy through blood, wherein the spectrometer emits at least one primary radiation signal of a wavelength of between about 750 and 2500 nm that is directed through the transmission output to a wall of the body lumen, and wherein the transmission input collects radiation directed from the body lumen wall; anda controller system comprising computer-readable memory programmed to store the signal measured by the spectrometer and to enable the controller to ...

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Номер записи: 100