КОМПОЗИЦИИ, СОДЕРЖАЩИЕ ЭПОТИЛОНЫ, И ИХ ПРИМЕНЕНИЕ ДЛЯ ЛЕЧЕНИЯ КАРЦИНОИДНОГО СИНДРОМА

Настоящее изобретение относится к области лекарственных средств, в частности к применению соединения формулы I, в котором А обозначает О, R обозначает метил, R' обозначает метил и Z обозначает О (эпотилон В), или его фармацевтически приемлемой соли для лечения карциноидного синдрома. Кроме того, изобретение относится к способу лечения карциноидного синдрома. Технический результат заключается в расширении арсенала средств лечения карциноидного синдрома. 2 н. и 1 з.п. ф-лы.

ВПУСКНОЕ УСТРОЙСТВО

Изобретение относится к области медицины. Впускное устройство (10) для мешка для хранения текучей среды содержит корпус (12), имеющий нижнюю стенку (14) и противоположные боковые стенки (16, 18), и соединительное отверстие (20) в указанном корпусе (12) напротив нижней стенки (14) для соединения корпуса (12) с мешком. Соединительное отверстие (20) имеет площадь поверхности удлиненной формы, образованную широким центральным участком (22) и заостренными, противоположными в продольном направлении концами (24). Впускное устройство (10) также содержит, по меньшей мере, одно входное отверстие (26) в нижней стенке (14) для сообщения с внутренней частью мешка для хранения текучей среды через указанное соединительное отверстие (20) и, по меньшей мере, одну перегородку (32), поддерживающую указанные боковые стенки (16, 18) и ориентированную поперечно продольному направлению (34). Перегородка (32) имеет подрезанный край (36), находящийся на расстоянии от нижней стенки (14), который образует проход ...

СИСТЕМА ДЛЯ ПРИГОТОВЛЕНИЯ И ПРИВЕДЕНИЯ В ГОТОВЫЙ ВИД ТЕКУЧЕЙ СРЕДЫ, ОБРАЗОВАННОЙ СМЕШИВАНИЕМ СУХОГО ВЕЩЕСТВА И ЖИДКОСТИ

Изобретение относится к медицине и фармацевтической промышленности, а именно к системе для приготовления и приведения в готовый вид текучей среды (43), образованной смешиванием сухого вещества (39) и жидкости (41), в особенности среды для терапевтических целей, которая содержит следующие компоненты: а) первый контейнер (1) для приема жидкости (41) с участком (3) стенки, деформируемым для изменения объема против действия возвратного усилия; b) второй контейнер (35) для приема сухого вещества (39); с) передаточное устройство для установления сообщения между первым контейнером (1) и вторым контейнером (35). 3 н. и 13 з.п. ф-лы, 11 ил.

ДОБАВКА И МЕДИЦИНСКИЙ КОНТЕЙНЕР ДЛЯ ОБОГАЩЕННОЙ ЭРИТРОЦИТАМИ ЖИДКОСТИ

Изобретение относится к фармакологии, а именно представляет собой добавку для обогащенной эритроцитами жидкости. Добавка получена путем добавления ингибитора гемолиза и поверхностно-активного вещества в раствор для хранения крови. Значение HLB поверхностно-активного вещества составляет не менее 13, а число оксиэтиленовых групп в гидрофильном сегменте молекулярной структуры поверхностно-активного вещества - не менее 20. Ингибитор гемолиза представляет собой производное уксусной кислоты в виде витамина Е. Добавка обеспечивает высокую эффективность ингибирования гемолиза и превосходную характеристику хранения эритроцитов. 6 з.п. ф-лы, 6 ил., 3 табл., 4 пр.

ОБЪЕДИНЕННЫЕ СИСТЕМЫ ХРАНЕНИЯ И ДОСТАВКИ ПИТАТЕЛЬНЫХ КОМПОЗИЦИЙ

Группа изобретений относится к медицине и может быть использована для хранения и доставки питательных композиций. Объединенная система хранения и доставки питательных композиций содержит контейнер, образующий камеру, горлышко и проницаемую перемычку, а также прокалывающее устройство, присоединенное к контейнеру и включающее колпачок, контактирующий с горлышком контейнера, и колющий инструмент. Колющий инструмент включает выступающую часть, имеющую дальний конец, ограничивающий отверстие, и выполненную с возможностью перемещения между первым положением, при котором указанный дальний конец находится со стороны проницаемой перемычки, противоположной расположению камеры, и вторым положением, при котором указанный дальний конец находится с той же стороны перемычки, что и камера. При этом система снабжена пружиной, установленной в сжатом состоянии и взаимодействующей с колющим инструментом, воздействуя на его выступающую часть в направлении второго положения. Группа изобретений относится также ...

ПЕРЕДВИЖНАЯ СТОЙКА ДЛЯ ЛЕЙКОФИЛЬТРАЦИИ КРОВИ ИЛИ ЕЕ КОМПОНЕНТОВ

Изобретение относится к области медицины и может быть использовано на станциях переливания крови. Передвижная стойка для лейкофильтрации крови или ее компонентов через фильтры содержит колесную базу с ручкой, первое поддерживающее средство для подъема или опускания контейнеров с кровью или ее компонентами, второе поддерживающее средство для приемных контейнеров и привод для подъема или опускания первого поддерживающего средства. Привод выполнен в виде реверсивного редукторного электродвигателя, связанного через эластичную муфту с ходовым винтом, приводящим в поступательное движение ходовую гайку и связанный с ней внутренний цилиндр с закрепленным на нем первым поддерживающим средством относительно внешнего цилиндра. Внешний цилиндр и второе поддерживающее средство закреплены на колесной базе, ходовой винт зафиксирован в подшипниках, закрепленных на внешнем и внутреннем цилиндрах. На ручке колесной базы расположен переключатель режимов подъема и опускания первого поддерживающего средства ...

СПОСОБ ИЗГОТОВЛЕНИЯ КОНТЕЙНЕРА (ВАРИАНТЫ)

В способе формуют корпус, включающий камеру, в первой пресс-форме в чистой комнате и формуют часть контейнера во второй пресс-форме в чистой комнате того же класса, что и первая, при этом в части контейнера устройством для заполнения контейнера может быть выполнен прокол с образованием отверстия с возможностью восстановления ее герметичности. Затем собирают вместе часть контейнера и корпус в чистой комнате для получения пустой герметично закрытой камеры. Изобретение обеспечивает повышение герметичности, когда в части контейнера выполняют прокол. 14 з.п. ф-лы, 66 ил.

УНИВЕРСАЛЬНОЕ ФИКСИРУЮЩЕЕ УСТРОЙСТВО

Изобретение относится к медицине и фармацевтической промышленности и касается фиксирующего устройства для крепления к входному элементу контейнера. Фиксирующее устройство имеет корпус и иглу, размещенную внутри корпуса. Устройство допускает введение и закрепление внутри корпуса входных элементов разного размера. В некоторых вариантах осуществления закрепление входного элемента внутри корпуса осуществляют податливыми фиксаторами. В некоторых других вариантах осуществления входной элемент внутри корпуса закрепляют прижатием к нему корпуса с помощью элемента сжатия корпуса. Одновременно с закреплением входного элемента внутри корпуса между фиксирующим устройством и входным элементом выполнено непроницаемое для раствора уплотнение. 2 н. и 22 з.п. ф-лы, 12 ил.

ПРОБКА ДЛЯ СТЕКЛЯННОГО ФАРМАЦЕВТИЧЕСКОГО ФЛАКОНА

Пробка для стеклянного фармацевтического флакона из полимерного материала, имеющая с внутренней стороны уплотняющий корпус и раздаточный элемент на днище и резьбовой участок на стороне, прилегающей к горловине флакона, отличающаяся тем, что раздаточный элемент выполнен заедино с телом пробки в виде стержня прямоугольного сечения с помазком-лопаткой на рабочем конце и ребрами жесткости у основания, а уплотняющий корпус отделен от него кольцевой прорезью.

НАСОС-ДОЗАТОР

Предложение относится к дозирующим устройствам и может быть использовано преимущественно в медицине или фармацевтической промышленности, например, для дозаторов лекарственных средств в ампульном производстве, а также в любой области техники.Насос-дозатор состоит из корпуса с подающим и нагнетательным каналами, шибера с каналом, плунжера, рабочий конец которого размещен в дозирующей камере, и толкателя плунжера, выполненного с элементом для кинематического соединения с приводом. Толкатель выполнен разъемным, причем одна из его частей выполнена с цилиндрическими выточками, а элемент для кинематического соединения с приводом находится на другой его части. Другой конец плунжера выполнен с уступом и размещен в толкателе с возможностью взаимодействия с его стенками. Технический результат - улучшенная точность и стабильность дозирования, в особенности малых доз при одновременном повышении долговечности устройства. 1 з.п. ф-лы, 5 ил.

ДЕЗИНФИЦИРУЮЩАЯ КОМПОЗИЦИЯ, ИСПОЛЬЗУЕМАЯ ДЛЯ ДЕЗИНФИЦИРОВАНИЯ МЕДИЦИНСКОГО ОБОРУДОВАНИЯ, ИМЕЮЩЕГО МЕТАЛЛИЧЕСКИЕ ЧАСТИ

Изобретение относится к области санитарии и касается дезинфицирующих средств. Дезинфицирующая композиция, используемая для дезинфицирования медицинского оборудования, имеющего металлические части, содержит низкомолекулярную перкислоту, стабилизатор перкислоты и ингибитор коррозии, компоненты берут в определенных количественных соотношениях, причем перкислота не находится в состоянии равновесия, а композицию получают путем смешения двух растворов, один из которых включает низкомолекулярную перкислоту, а другой - ингибитор коррозии и стабилизатор пероксида и/или стабилизатор перкислоты. Предложенная двухмодульная композиция выполнена в виде двух модулей, при этом один модуль содержит первый водный раствор, включающий низшую алифатическую перкислоту, а другой модуль включает второй водный раствор, содержащий ингибитор коррозии и стабилизатор перекиси водорода и/или стабилизатор перкислоты. Композиция позволяет устранить коррозию металлов на оборудовании. 2 с. и 15 з.п. ф-лы.

Устройство для лейкофильтрации компонентов крови

Изобретение относится к области медицины, в частности к устройствам для лейкофильтрации. Устройство для лейкофильтрации компонентов крови содержит колесную базу с ручкой, первое поддерживающее средство в виде рамы с крючками, приспособленное для подъема или опускания контейнеров с компонентами крови, и второе поддерживающее средство в виде поддона для размещения приемных контейнеров, привод для подъема или опускания первого поддерживающего средства, аккумуляторную батарею, микроконтроллер, датчики веса, датчик напряжения, датчик тока, индикатор веса, индикатор разряда аккумуляторной батареи, индикатор окончания процесса лейкофильтрации, связанные с микроконтроллером. Привод выполнен виде реверсивного редукторного электродвигателя, связанного с ходовым винтом, приводящим в поступательное движение ходовую гайку и связанный с ней внутренний цилиндр с закрепленным на нем первым поддерживающим средством относительно внешнего цилиндра, внешний цилиндр и второе поддерживающее средство закреплены ...

Контейнер для лиофилизации и способ его использования

Изобретение относится к медицинской технике, используемой в трансфузиологии. Гибкий контейнер выполнен из двух пленочных мембран, одна из которых гидрофобная газопроницаемая, но непроницаемая для микробных контаминантов и гемокомпонентов. Вторая прозрачная мембрана – газо-, водонепроницаемая. Контейнер содержит присоединительные элементы и позволяет вне асептических условий подготавливать к лиофилизации и лиофилизировать гемокомпоненты. Способ обеспечивает проведение лиофилизации, герметизацию газопроницаемой мембраны после лиофилизации, стерильный пробоотбор и хранение в сложенном виде компактного и маловесного контейнера с лиофилизатом в вакуумированном влагозащитном и газонепроницаемом пакете. Технический результат состоит в сохранении качества и снижении риска микробной контаминации восстановленного из лиофилизата гемокомпонента, в частности плазмы крови. 2 н. и 25 з.п. ф-лы, 11 ил.

ГЕРМЕТИЧНЫЙ КОНТЕЙНЕР И СПОСОБ ЕГО ИЗГОТОВЛЕНИЯ ИЗАПОЛНЕНИЯ

... 1. Пузырек в сборе для хранения вещества, содержащий корпус, снабженный отверстием, камеру, в которую через отверстие может быть введено вещество, основание, среднюю часть и верхнюю часть, которая отделена в направлении оси от основания средней частью, причем размеры основания и верхней части в горизонтальной плоскости больше, чем максимальный размер средней части в горизонтальной плоскости, и заглушку, которая введена в отверстие и в которой иглой или иным подобным элементом может быть выполнен прокол для осуществления, по крайней мере, одного из следующих действий: введения в камеру вещества или извлечения его из камеры. 2. Пузырек в сборе по п.1, отличающийся тем, что поперечное сечение основания, средней части и верхней части имеет примерно форму окружности, и максимальный диаметр основания и верхней части больше максимального диаметра средней части. 3. Пузырек в сборе по п.2, отличающийся тем, что основание, средняя и верхняя часть создают форму, сходную с катушкой. 4. Пузырек в сборе ...

АЛЬБУМИН В ГИБКОМ ПОЛИМЕРНОМ КОНТЕЙНЕРЕ

... 1. Способ упаковки белка альбумина, предусматривающий стадии обеспечения гибкого полимерного контейнера, имеющего отверстие, продолжающееся от полости полимерного контейнера, обеспечения некоторого количества альбумина в виде стерильного раствора некоторой концентрации, введения альбумина под давлением магистрали подачи раствора, составляющим от около 4 psig до около 20 psig, в полость полимерного контейнера через имеющееся в нем отверстие, и запечатывания отверстия для заключения жидкого альбумина внутри камеры, непроницаемой для текучей среды, в полости полимерного контейнера. 2. Способ по п.1, в котором альбумин поддерживают при температуре около 68°F (20°С) перед введением в полость контейнера. 3. Способ по п.1, в котором альбумин вводят в полость гибкого полимерного контейнера под давлением магистрали подачи раствора, составляющим от около 12 psig до около 16 psig. 4. Способ по п.1, в котором гибкий полимерный контейнер изготавливают в асептической среде формующего-заполняющего-запечатывающего ...

УСТРОЙСТВО ДЛЯ БЕЗОПАСНОГО ПЕРЕЛИВАНИЯ КРОВИ ИЛИ ЕЕ КОМПОНЕНТОВ И СПОСОБ ЕГО ИСПОЛЬЗОВАНИЯ

... 1. Устройство для безопасного переливания крови или ее компонентов, помещенных по меньшей мере в один пакет (1) по меньшей мере с одной трубкой (2) в днище, выполненной из упругодеформируемого материала, например, резины и т.п. и предназначенной для выпуска крови или ее компонентов, относящихся к заданной группе крови с соответствующим резус-фактором, отличающееся тем, что оно содержит пережимающее устройство (3; 74), которое закрыто соответствующими зажимными средствами (14, 15; 77, 78), выполненными с возможностью перемещения относительно указанной трубки (2) для предотвращения прохождения по ней выходящей из пакета (1) крови или ее компонентов и которое содержит посадочное место (4), на котором сформированы элементы (6, 7; 79), пригодные для кодирования и идентифицирования указанной группы крови и соответствующего резус-фактора и взаимодействующие с уникальным ключом (19; 66), предназначенным для открывания в случае совместимости крови или ее компонентов указанного пережимающего устройства ...

Картридж для приготовления напитков, содержащий активные фармацевтические ингредиенты

Группа изобретений относится к области приготовления напитков, содержащих активные фармацевтические ингредиенты. Картридж с активными фармацевтическими ингредиентами для использования в автоматической машине игольчатого типа для приготовления напитков, содержит основную часть, содержащую первый активный фармацевтический ингредиент в форме порошка, и крышку, выполненную из многослойного материала, включающего внешний слой и внутренний слой. При этом картридж изготовлен из устойчивого на разрыв материала, характеризующегося конечным показателем скорости проникновения водяных паров от приблизительно 2×10г на картридж в сутки до приблизительно 2×10г на картридж в сутки. Также раскрыта крышка картриджа с активными фармацевтическими ингредиентами и картридж с такими активными фармацевтическими ингредиентами как: дефингидрамин и ацетаминофен. Группа изобретений обеспечивает долгосрочную стабильность фармацевтических ингридиентов. 3 н. и 11 з.п. ф-лы, 7 ил., 6 табл., 3 пр.

Упаковка для мягкой лекарственной формы индивидуального изготовления

Изобретение относится к области фармации и может быть использовано в аптеках. Упаковка представляет собой банку цилиндрической формы, в торце которой имеется круглое отверстие для выдавливания мази. Отверстие закрывается крышкой с коническим выступом, совпадающим с отверстием при завертывании крышки. Банка снабжена крестовиной-гайкой и поршнем, соединенным с мешалкой. Мешалка имеет четыре лопасти, которые попарно расположены под углом 45 градусов к плоскости мешалки в противоположном направлении: две лопасти по диаметру с наклоном в одну сторону, две в другую сторону, расположение лопастей под углом 90 градусов относительно друг друга (в форме креста). При достижении поршня крышки банки по окончании мази в упаковке происходит сжатие лопастей в одну плоскость с мешалкой. Крестовина-гайка используется для поднятия поршня. Достигается улучшенная гомогенизация и максимальная степень выдавливания мягкой лекарственной формы из упаковки при сохранении стерильности мягкой лекарственной формы за ...

МЕШОК ДЛЯ СТЕРИЛЬНОГО РАСТВОРА ПРОДУКТА

ПЛАСТИКОВОЕ КОНТЕЙНЕРНОЕ ИЗДЕЛИЕ

КАССЕТА-СТЕРИЛИЗАТОР

Кассета-стерилизатор может быть применена для хранения, стерилизации, транспортировки и удобного использования, например, Т-образных игл в иглорефлексотерапии (ИРТ). Кассета имеет корпус с загнутыми сверху краями вовнутрь по длине и наружу с торцов для свободного помещения и фиксации площадки с отверстиями и соответственно загнутыми краями для помещения и фиксирования на ней крышки. Работу кассеты-стерилизатора можно описать на примере использования в иглорефлексотерапии. Легким нажатием пальцами с торцов корпуса ближе к площадке можно снять площадку с собранными на ней иглами и закрытыми крышкой. Подвергать иглы предстерилизационной обработке при помощи щетки в моющих растворах согласно инструкций, принятых в здравоохранении. Далее собрать кассету-стерилизатор в обратном порядке и подвергать стерилизации, например, в воздушном стерилизаторе типа ГП-8. После стерилизации и остывания кассета-стерилизатор берется непосредственно руками. Рефлексотерапевт, передвигая большим пальцем одной руки ...

ДОБАВКА И МЕДИЦИНСКИЙ КОНТЕЙНЕР ДЛЯ ОБОГАЩЕННОЙ ЭРИТРОЦИТАМИ ЖИДКОСТИ

... 1. Добавка для обогащенной эритроцитами жидкости, полученная путем добавления ингибитора гемолиза и поверхностно-активного вещества в раствор для хранения крови, в которойзначение гидрофильно-липофильного баланса (HLB) поверхностно-активного вещества составляет не менее 13; ачисло оксиэтиленовых групп в гидрофильном сегменте молекулярной структуры поверхностно-активного вещества - не менее 20.2. Добавка для обогащенной эритроцитами жидкости по п.1, отличающаяся тем, чтогидрофильный сегмент молекулярной структуры поверхностно-активного вещества состоит из полиоксиэтиленсорбитана;а раствор для хранения эритроцитов представляет собой смешанный раствор, содержащий маннитол, глюкозу, аденин, фосфатную соль, цитратную соль и хлорид натрия.3. Добавка для обогащенной эритроцитами жидкости по п.1, отличающаяся тем, чтогидрофильный сегмент в молекулярной структуре поверхностно-активного вещества состоит из полиоксиэтиленсорбитана;а раствор для хранения эритроцитов представляет собой смешанный раствор ...

КОЛПАЧОК ПРОБИРКИ 187

Изобретение относится к эластомерному колпачку, который используется для герметизации пробирки, однако обеспечивает доступ пипетки к содержащейся в пробирке жидкости. Колпачок включает в себя кольцеобразный фланцевый участок для закупоривания пробирки и имеющий уклон участок усеченного конуса для упрощенного направления пипетки в пробирку. Участок трубчатого уплотнителя, соединенный с фланцевым участком и участком усеченного конуса, выполнен так, что он окружает участок усеченного конуса и с легкостью введения плотно входит в зацепление с внутренней стенкой пробирки. Участок центрального клапана, соединенный с участком усеченного конуса, на своей верхней поверхности окружен желобом для протыкания пипеткой и имеет гибкий участок. Участок центрального клапана отделяется по периметру желоба, но над гибким участком шарнирно откидывается на желобе и не отделяется. Соотношение диаметров пипетки и участка центрального клапана таково, что во время переноса содержащейся в пробирке жидкости проблемы ...

РУЧКА

... 1. Гибкий однокамерный или многокамерный пакет (10) для содержания лекарственных препаратов, содержащий подвесной клапан 11, отступающий от верхнего края указанного пакета, отличающийся тем, что указанный клапан 11 включает:a) две ориентированные в зеркальном отображении округлые прорези (1) и (2) под углом 145-180°, причем один конец каждой из указанных прорезей (1) и (2) соединен соединительной прорезью (3), являющейся по существу прямолинейной и имеющей длину в 4-10 раз больше радиуса указанных округлых прорезей (1, 2), иb) две ориентированные в зеркальном отображении округлые прорези (4) и (5) под углом 180-270°, имеющие радиус, составляющий 0,3-0,7 радиуса указанной прорези (1) и (2), причем один конец каждой из указанных прорезей (4) и (5) соединен соединительной прорезью (6), имеющий U-образную форму,c) причем указанные прорези (1), (2), (4) и (5) расположены относительно общей оси зеркальной симметрии через центры указанных прорезей (3) и (6) и основы указанной U-образной конфигурации ...

УПАКОВКА ДЛЯ АЭРОЗОЛЬНОЙ ТАРЫ И СПОСОБ ЕЕ ИЗГОТОВЛЕНИЯ

... 1. Способ поддержания замкнутого объема герметичной упаковки под давлением, приблизительно равным давлению окружающей среды, где данная упаковка включает аэрозольную тару с ингалятором с дозированной порцией (ИДП), содержащую лекарственный препарат и гидрофторалкановый пропеллент (ГФА), выбранный из группы, состоящей из ГФА 134а и ГФА р227 или их смеси, где способ включает следующие стадии: (i) помещение эффективного количества адсорбента ГФА и упомянутой аэрозольной тары внутрь герметизируемой упаковки; (ii) герметизация упаковки так, чтобы аэрозольная тара и адсорбент ГФА находились в замкнутом объеме внутри упаковки под давлением, приблизительно равным давлению окружающей среды; и (iii) адсорбирование любой утечки ГФА пропеллента адсорбентом ГФА для поддержания указанного замкнутого объема под давлением, приблизительно равным давлению окружающей среды. 2. Способ по п.1, отличающийся тем, что лекарственный препарат выбирают из группы, состоящей из бронхолитических, антигистаминных, противовирусных ...

FLÜSSIGKEITSABGABEVORRICHTUNG MIT EINGEBAUTER PHIOLENBEFESTIGUNG ODER EINGEBAUTEM PHIOLENADAPTOR

Fibrinogenextraktion

Griffelement für Sterilisierbehälter

Medizinischer Fluidbeutel

Fluidbeutel, welcher wenigstens einen Auslaufstutzen (2) aufweist, der mit einer schaltbaren Ventileinrichtung (3) zur Außenumgebung hin mittels einer sterildicht auf dem Auslaufstutzen (2) angeordneten Verschlusseinrichtung (4) verschlossen ist, wobei die Verschlusseinrichtung (4) ein auf dem Auslaufstutzen (2) angeordnetes Basisteil (5) und eine Abbrechkappe (8) aufweist, wobei Basisteil (5) und Abbrechkappe (8) über eine als Sollbruchstelle dienende Verbindung (6) einstückig miteinander verbunden sind, wobei die Ventileinrichtung (3) in ihrem Inneren einen Ventilstößel (10) aufweist, der die Ventileinrichtung (3) nach Entfernen der Abbrechkappe (8) bei bestimmungsgemäßem Gebrauch des Fluidbeutels (1) auf Druck öffnet, wobei im Inneren der Abbrechkappe (8) der Verschlusseinrichtung (4) ein Ventilbetätigungselement (9) vorgesehen ist, welches nach Verbindung von Auslaufstutzen (2) mit Verschlusseinrichtung (4) den Ventilstößel (10) eindrückt und so die Ventilreinrichtung (3) derart öffnet ...

NADELLOSE ZUGRIFFSVORRICHTUNG FÜR EIN MEDIZINFLÄSCHCHEN

Verbesserte Injektionsstelle

COMPUTER-CONTROLLED MEDICAL CARE SYSTEM

Verschluss für eine Medikamentenflasche und Verfahren zur Herstellung dieses Verschlusses.

UNABHAENGIGE UND UNIVERSALE VERBINDUNG FUER ROHRSTUTZEN VON ENTERALEN ERNAEHRUNGSSCHLAEUCHE.

Verschlussvorrichtung für einen flexiblen Schlauch.

Verpackter Gegenstand.

Injektionsstelle

Stumpfer Einstechdorn.

Vorrichtung zum Öffnen einer Leitung

Verbinder mit Verriegelungsring für eine Phiole

Vorrichtung zum Einleiten von Luft in bei der künstlichen Ernährung verwendete Behälter

Receptacle for medicinal fluid with cap=type closure piece

The bottle or receptacle may be for medicine which may be in liquid form. The end of the disc-shaped elastic sealing element (40) pointing towards the receptacle (10) has a flange (42) all round welded to the base of the cap (22). The side of the cap facing the bowl-shaped recess (26) has a fixture flange (24) which is sealed to a counter-flange (12) of the receptacle containing medicinal fluid.

Verschlußkappe und Verfahren zur gasblasenfreien Füllung von Behältern

A closure cap for closing containers without gas displaces part of the container content when it is set upon the neck of the container and at the same time allows confined gas to escape through one or several openings before snapping into its closing position.

Behälter mit einem Luer-Filter zur Verabreichung eines Arzneistoffes

VERDUENNUNGSSYSTEM ZUR VERDUENNUNG HOCHVISKOSER LOESUNGEN AUS BLUTBESTANDTEILEN

Injection moulded cap for medical port connector has integral spacer connecting it via section of weakness to base of port connector so it can be separated by turning, protective foil being fitted over base of cap

The injection moulded cap (5) for a port connector has an integral spacer (10) attached which is connected via a section of weakness (4) to the base (11) of a port connector (3) and can be separated from it by turning. A protective foil (6) is fitted over the base of the cap and has a tab (8) allowing it to be peeled off.

Abgabebehälter mit Filter, sowie Verschluss für einen Abgabebehälter

Originalitätsversiegelung für Verschlüsse stutzenförmiger Anschlüsse eines Behältnisses

Originalitätsversiegelung (10) für Verschlüsse (12, 14) von zumindest zwei stutzenförmigen Anschlüssen (16, 18) eines Behältnisses (20) wie Infusionslösungsbeutel, dadurch gekennzeichnet, dass die Originalitätsversiegelung (10) als eine Enden (28, 30) der Anschlüsse (16, 18) verbindende und die Verschlüsse (12, 14) umschließende bandförmige Schrumpffolie ausgebildet ist.

Flexibler Kunststoffbeutel für medizinische Lösungen

Vorrichtung zur Trockenvernebelung

Die vorliegende Erfindung betrifft eine Vorrichtung zur Trockenvernebelung von vernebelbarem Material, das in einem gasdichten Behälter mit einem gasdichten Behälterverschluss enthalten ist, und eine Gaszuleitung 5, deren erstes Ende mit einer Trägergasquelle verbindbar ist und deren zweites Ende durch den Verschluss hindurchführbar ist, eine durch den Verschluss hindurchführbare Trockennebel-Ableitung 6 zum Ableiten eines in dem Behälter erzeugten Trägergas-Trockennebels des vernebelbaren Materials sowie eine durch den Verschluss hindurchführbare Überschuss-Ableitung 7 zum Ableiten zumindest eines Überschusses an Trägergas in dem Behälter umfasst. Gemäß einem weiteren Aspekt betrifft die Erfindung eine entsprechende Vorrichtung, welche den gasdichten Behälterverschluss 3 umfasst, durch den die Gaszuleitung 5, Trockennebel-Ableitung 6 und Überschuss-Ableitung 7 hindurchgeführt sind. Darüber hinaus betrifft die Erfindung Systeme, bestehend aus der Vorrichtung 1 und dem gasdichten Behälter ...

Bügeletikett

Etikett aus einer flexiblen Folie mit einem ersten Bereich (2a), der an einer Oberfläche (6) befestigbar ist, und einem zweiten bügelförmigen Bereich (2b), der reckfähig ist dadurch gekennzeichnet, dass der zweite Bereich (2b) Mittel aufweist, die dessen Reckfähigkeit zumindest abschnittweise einschränken.

Improvements in liquid dispensing containers

... 739,626. Drop delivering stoppers; spouts. FOXBORO CO. Feb. 2, 1954 [Feb. 5, 1953], No. 3132/54. Classes 66 and 125 (3). A closure and dispensing device for a flexible container 10 has a closure plug 11 with a flexible spout 13 and liquid receiving tube 14, secured to the container by a screw cap 12, the end of the spout being closed when not in use by insertion in a recess 14 in the plug 11 which also contains a filter 17 in the liquid passage. In a modification the spout is received in a recess in the screw cap. In another modification (Fig. 5) a flexible bottle 25 has a flexible spout 26 integral therewith and a thickened wall portion 30 with a recess 31 to receive the free end of spout 26.

IMPROVEMENTS IN OR RELATING TO SEALED CONTAINERS

... 1285066 Blood containers UNION CARBIDE CORP 26 Sept 1969 [9 Oct 1968] 47400/ 69 Heading A5R [Also in Division B8] A flexible sterile plastics container 10 for colecting, storing, and dispensing viable fluids, especially blood, comprises a storage compartment 14 for the fluid and two end compartments 16, 18 containing plastics fluid collecting conduits 20, 21 and a fluid dispensing conduit 22 respectively. The compartments are separated and the conduits permanently sealed to the container walls and the inner walls of the conduits are releasably sealed together at 27 by transverse heat seals 24, 26. The ends of the container 10 are sealed and compartment 16 divided by heat seals 28, 29, 30, and notches 36 are provided to facilitate opening. A secondary seal (27') may be made in conduit 22 or an elongated plug inserted. In a modification, the seal 29 is omitted, the conduits are made longer, and a deep opening notch (44) surrounded by a seal (42) is provided adjacent seal 26.

PARENTERAL SOLUTION CONTAINERS

... 1376768 Parenteral solution containers BAXTER LABORATORIES Inc 13 Oct 1972 [20 Oct 1971] 47303/72 Heading A5R A pierceable closure for a parenteral solution container 10, comprises a flexible plastics tube 26 integral with the container 10 and closed at its outer end 28 and a tubular gripping sleeve 30 positioned about the tube 26 such that its outer end 28 lies in the bore of the sleeve 30, the sleeve having an open bore of uniform cross-section outwardly of the end 28 of the tube 26 to the outer end of the sleeve 36. The container 10 has two such closures 20, 21 one of which may be sealed with a pierceable latex plug 22 for the addition of supplemental medication and the other having a tubular cover with a removal tab. The closed end 28 defines a diaphragm which is accessible to a hollow spike 32 through which the solution may be transferred when the diaphragm is pierced by the spike 32.

CONTAMINATION-RESISTANT DROP-DISPENSING AND METERING DEVICE.

A device for dispensing liquid drops, such as drops of medicine, in a controlled fashion while protecting the rest of the liquid from inadvertent contamination is provided by an elastically deformable container with a composite membrane (4) across a passageway between the body of the container and a delivery orifice. The composite membrane (4) has one component (5) that is liquophilic and one (6) that is liquophobic, both components having pore sizes to resist the passage of contaminant.

Fluid container

A device for preparing a pharmaceutical or medicinal product

A device for preparing a pharmaceutical or medicinal product comprises at least one filtering nozzle 22 intended to be fitted on a syringe for aspiration of a product wherein the syringe is a fixed or removable injection needle, the filtering nozzle 22 has a first tubular part 24 for attachment to the syringe, an intermediate tubular part 26 intended to receive the needle of the syringe and having an internal diameter smaller than that of the first tubular part 24 and a flat aspiration head 28 with a free open end equipped with a filtering membrane 30. Advantageously, the device is contained in a sterile package consisting of a box (40, Fig 2) made of a plastic material and having a compartment (44, Fig 2) for accommodating the nozzle 22 and a compartment for a metallic receptacle 10 which can be used for mixing the dry product with water prior to use.

Blister-type reservoir pack with reservoir piercing means

The pack assembly comprises at least a blister-type reservoir pack 1 and a reservoir piercing means 4 that is carried by the pack and movable with respect to it. The piercing means is supported by the carry means 7, which is slidable with respect to the pack in direction 13 along means 18. The piercing means may also be rotatable (3, Fig.4), in order to allow selective positioning over a frangible portion 17 of the reservoir to be able to pierce it. The assembly may include a cover 8, which can be adhesive, surrounding at least partially the pack, and the carry means and the piercing means may be optionally connected to the cover instead of to the blister pack itself. The cover may also have non-frangible portions on which the piercing means could rest to avoid accidental piercing, and the assembly may have a sub frame or bangle 16 for attaching to a users arm. Other embodiments show the piercing means carried on a cover (27-29, fig.7) within which a blister pack can slide, and a plurality ...

SEALING CAP

RESEALING INTRAVENOUS CONTAINER

Package for storage of medical container

A package for storing therein a medical container in conjunction with a deoxidizer covered on at least one side thereof with a gas-impervious sheet and on at least one other side thereof with a gas-pervious sheet, which package is characterized by comprising a tightly sealed container adapted to hold the aforementioned deoxidizer in such a manner that the gas-pervious sheet sides of the deoxidizer rests on at least one of the inner sides thereof and provided in the inner side thereof adjoining the gas-pervious sheet side of the aforementioned deoxidizer with at least one passage for gas communicating with the atmosphere enclosed with the package.

Tamper-indicating pierceable closure

It is difficult to detect whether the rubber seal on a vial or on a hypodermic syringe cartridge has been penetrated, because the rubber seal over the mouth of the container is purposely soft and self-sealing to prevent contamination of the fluid within the container. As a result pilfering of narcotics from such containers has gone largely undetected. To remedy this situation, a blister-like sac of a plastic film and containing a harmless dye is mounted within the mouth of the container between the rubber seal and the contents of the container. It is impossible for a hypodermic needle to be inserted through the seal and into the fluid within the container without puncturing the blister-like sac and thereby releasing the harmless dye into the fluid within the container. Thus, if the seal has been broken, the fluid in the container will be tinted with the color of the harmless dye.

A container with a temperature activated lock

A device comprises a first part1,22containing a temperature-sensitive material, e.g. a liquid containing a pharmaceutical agent, a second part11,38which engages the first part and can be disengaged or displaced to allow the material to be dispensed or utilised, a locking means17, and a temperature-sensitive activator6,23for the locking means that is activated at a predetermined temperature, and thereby irreversibly prevents the material from being dispensed or utilised. The temperature activated material may be a bi-metal, bi-plastic or shape memory alloy. The device may include an indicator14showing the state of the temperature sensitive lock. The container may be a vial1or a syringe22.

Vial

There is disclosed a vial having a cap ordinarily closed by a one-way valve and capable of being engaged by the barrel of a hypodermic syringe to enable the syringe to be charged with fluid from the vial when inverted. Preferably the one-way valve is a spring-pressed ball. Preferably the cap is externally screw threaded to mate with a screw threaded syringe. The arrangement minimises contamination for multi-dose vials without the possibility of the syringe being contaminated with latex.

Improvements in tags

Closure member with septum

A medical injection device comprising a container having an inner storage for holding a fluid, a closure member having a septum barrier that provides a seal for the fluid in storage, a piston having a hollow needle that pierces the septum when pressure is applied to the rear of said container providing a flow path for said liquid. Preferably, the piston may have one or more seals that may be coated, constructed from one or more materials that includes elastomer blend, thermoplastic elastomer or a polymer. Preferably the inner storage will be pre-filled or have a method for re-filling. Preferably the combination of seals above the closure member septum will provide sterility during storage. Further embodiments will preferably include a modular dispenser for use with a smart phone, and a wearable device.

Valve assembly and dispenser

Fitments for containers from which liquid is intended to be withdrawn by a hollow needle or tube

A container 2 provided with a self-sealing closure member 4, through which a needle may be inserted to withdraw liquid 3 from the container 2, is fitted with a sterilizing cap 1. The space within the upper region of the cap 1 is divided into compartments 20, 21, each containing a sterilizing substance. A needle can be caused to penetrate a weakened region of the cap 1 and to pass through one of the compartments prior to penetrating the closure member 4 and being introduced into the liquid 3 within the container 2. After the needle has been passed through one of the compartments a number of times, it may be passed through another of the compartments which contains fresh sterilizing substance. ...

Needle assembly

There is disclosed a needle assembly comprising a needle, a needle-retaining portion, a removable needle protector portion, and a resilient member for removing liquid from the surface of the needle which is disposed around the needle rearward of its point. The liquid removing member has a needle-accommodating opening with a diameter approximately that of the outside diameter of the needle. The member is contained within the needle protector portion and removable from the needle with the removal of the needle protector portion from the assembly. Also disclosed are blood bag systems comprising a donor bag and the aforementioned needle assembly.

COMPOSITIONS AND USES THEREOF

TAMPER-PROOF SEALING DEVICES AND ITEMS EQUIPPED WITH THEM

... 1522798 Tamperproof seals AVON MEDICALS Ltd 10 Nov 1975 [18 Nov 1974] 49836/74 Heading B8T A tamperproof seal for an access opening, e.g. in a blood bag, includes a first tamperproof seal denying access until it has been destroyed and a second access-denying means to re-seal the opening made available on the destruction of the first seal, the second access-denying means being arranged to indicate disturbance from its sealing position. The seal comprises a tubular portion 5 attached by a weakened portion 8 to a block 9 integral with a strap 13 having a ring 14 at its extreme end and also an aperture part-way along its length. The second access-denying means is in the form of a plug 3 attached to the block 9 by a stem 21 and stud 22 received in a complementary opening in the block. Assembly.-To assemble the seal, the strap 13 is turned over through 360 degrees so that the aperture part-way along its length engages the plug 3 and the ring 14 is passed under the tubular portion 5 and received ...

POLYURETHANES FOR ARTICLES FOR MEDICAL USE

Flat flexible containers and related valves, and process and apparatus for their manufacture under absolutely sterile conditions

A flat, flexible, sterilizable container for a liquid to be maintained and extracted under sterile conditions, said container comprising: a body having walls formed by a three-layer laminate including an outermost layer of a propylene polymer, an innermost layer of a copolymer of ethylene with a small amount of butylene, and an intermediate layer of an amide polymer; and a valve carried by said body comprising an elastomeric core whose spaced major faces are covered, one, by a three-layer laminate similar to said body wall forming laminate and, the other, by a two-layer laminate including a first layer of a copolymer of ethylene with little butylene and a second layer of an amide polymer.

LIQUID DISPENSING BOTTLE

MEDICAL LIQUID BOTTLE HAVING A FUSED CLOSURE STRUCTURE

... 1469043 Seaming AMERICAN HOSPITAL SUPPLY CORP 21 Feb 1975 [26 Feb 1974] 7393/75 Heading B5K [Also in Divisions B8 and A4] A medical liquid bottle has a neck 8 secured to a dispensing adapter 9, an upstanding collar 16 on the adapter telescopically fitting into an upstanding collar 18 on the neck with the outer terminal ends 17, 19 of the collars being near to each other and fused together to form a joint the side surfaces of which converge together. A heating die with an annular groove (31), Fig. 5 (not shown), may be used to fuse the ends together, the side walls of the groove being inclined at an angle of 20-50 degrees to one another. The end 17 may be slightly higher than the end 19 and engage one side wall of the groove before the end 19 engages the other side wall so that air can escape from the groove before the ends are sealed together. Alternatively the ends may be sealed ultrasonically. The bottle and adapter may be of a propylene-ethylene copolymer. The adapter has a tubular medication ...

IODINE DISPENSERS

ADAPTOR FOR COUPLING WITH A MEDICAL CONTAINER

Device for holding blister pack.

A device for holding blister packs has first ans second members, which are operable between an open condition to allow removal of products from the blister packs, and a closed condition to prevent this. The blister packs are not removable from the device. The blister packs may be retained by panels overlying their bases. The members can be retained in their closed condition by a child-resistant closure.

Closing system for a container

Adaptor for coupling with a medical container

Improvements with the flexible matter bottles in particular for medicamentous products.

Contamination-resistant dispensing and metering device.

Adaptor for coupling with a medical container

Device for holding blister pack

Closing system for a container

Adaptor for coupling with a medical container

Closing system for a container

Device for holding blister pack

TRANSITION EQUIPMENT FOR AND MEDICAL CONTAINERS FELL

MEDICAL PRODUCTS AND ORDER DEVICE

DONATION DEVICE

DEVICE FOR INTRODUCING AIR INTO CONTAINERS USED WITH THE ARTIFICIAL NUTRITION

CATCH DIAPHRAGM FOR A PACKING FOR PRODUCTS WHICH CAN BE STERILIZED WITH A HIGH TEMPERATURE STERILIZATION FLUID

USE OF A CONTAINER FOR A MEDICAL LIQUID

STRIP PACKING FOR SEHBEHINDERTE

VORRICHTUNG ZUM EINFUEHREN EINER WAESSERIGEN LOESUNG WENIGSTENS EINES MEDIKAMENTES OD.DGL. IN EINEN KOERPERHOHLRAUM

PERFORATE-CASH CATCH

BEHÄLTER ZUR EINBRINGUNG ZUMINDEST EINES UNSTERILEN GEFÄSSES IN EINEN STERILEN BEREICH

Fluid safety dispenser

A fluid safety dispenser system having a fluid storage container keyed to a fluid dispenser. The container having a valve body positionable in the opening of the container, the valve body having a plug member biased to allow fluid passage through the opening of the container when in a displaced position and to eliminate fluid passage through the opening of the container when the plug member is in a seated position. The keyed fluid dispenser assimilates a syringe and is releasably securable to the valve body for use in depressing the plug member by movement of a leaf spring when the keyed fluid dispenser is in position. The keyed fluid dispenser has indicia to provide for exact measurement and can be temporarily coupled to the container to provide ease of fluid transfer.

System and Method for Intermixing the Contents of Two Containers

A system and method for intermixing the contents of two containers. The system includes a first container, a second container, and a connector for providing fluid communication between the first and second containers. The connector includes at least one resilient retention member for securing the first container to the connector. In addition, the connector accommodates standard vials containing, for example, medicaments, and prevents the unwanted discharge of the contents of the vial into the environment.

Systems and methods for safe medicament transport

A medicament transport system includes a syringe adapter assembly; and a vial adapter assembly including a base defining an opening having a seal member disposed therewithin, a stem extending from the base and defining a lumen therethrough and an opening through a wall thereof, a needle shuttle valve slidably disposed within the lumen of the stem and supporting a transfer needle and a vacuum needle; and a vacuum cup slidably supported on the stem, wherein a vacuum chamber is defined in the space between the base, the stem and the vacuum cup. The medicament transport system includes a condition where the transfer needle and the vacuum needles penetrate the seal member of the vial adapter assembly, and the vacuum cup is moved to draw a vacuum through the vacuum needle. An automation system is provided that utilizes a medicament transport system for forming a medicament solution from a liquid/non-liquid solution.

Connector for a container including a medicinal active ingredient

The invention relates to a connector for containers containing medicinal active ingredient, which connector makes it possible to transfer active ingredient from one container into another container. The connector ( 1, 1 ′) according to the invention comprises a first connection region ( 3, 3 ′) for the connection of a first container ( 2, 2 ′), a guide element ( 4, 4 ′), a piercing element ( 5, 5 ′) and a partition wall ( 6 ), wherein the guide element ( 4, 4 ′) has a duct ( 7 ) designed for transferring a medicinal active ingredient, the piercing element ( 5, 5 ′) is arranged, at least in certain sections, in the duct ( 7 ) and is axially movably guided within the duct ( 7 ) by the guide element ( 4, 4 ′), and, by connecting a container ( 2, 2 ′) in the first connection region ( 3, 3 ′), the piercing element ( 5, 5 ′) can be moved from a starting position, in which the piercing element ( 5, 5 ′) does not open the partition wall ( 6 ), into an end position, in which the piercing element ( 5, 5 ′) opens the partition wall ( 6 ) in order to transfer a medicinal active ingredient.

Drug solution delivery device for medical use

A cylindrical body ( 30 ) that is inserted into a drug solution container ( 70 ), a connection port ( 15 ) to which a syringe ( 40 ) is connected, and a connector ( 50 ) that is connected to a port ( 110 ) of an infusion bag ( 100 ) communicate with a cavity ( 11 ) of a delivery device main body ( 10 ). A first check valve ( 21 ) that functions to permit the flow of drug solution toward the cavity from the drug solution flow path and restrict the flow of drug solution in the opposite direction is provided on a flow path between a drug solution flow path ( 31 ) of the cylindrical body and the cavity. A second check valve ( 22 ) that functions to permit the flow of drug solution toward the connector from the cavity and restrict the flow of drug solution in the opposite direction is provided on a flow path between the connector and the cavity. Drawing a plunger ( 45 ) of the syringe in and out enables a drug solution ( 72 ) contained in the drug solution container to be efficiently transferred to the infusion bag.

METHODS AND APPARATUS FOR BUFFERING PARENTERAL SOLUTIONS

A system for transferring solutions from a first cartridge into a second cartridge comprises a cartridge holder, a plunger driver, and a cartridge connector. The cartridge connector carries a transfer needle and an exhaust needle. The cartridge holder positions the first cartridge against the cartridge connector so that the transfer needle penetrates the first cartridge septum. The second cartridge is removably inserted into another end of the cartridge connector so that both the transfer needle and the exhaust needle penetrate the second cartridge septum. The plunger driver is disposed to advance a plunger on the first cartridge to transfer solution from the first cartridge into the second cartridge thus displacing solution from the second cartridge through the exhaust needle. The cartridge connector includes a sealed interior waste chamber for receiving the solution from the second cartridge. 1. A device for transferring a volume of a solution from a first cartridge having a septum to another solution in a second cartridge having a septum , said device comprising:a cartridge holder having a proximal end, a distal end, and a chamber for removably holding the first cartridge;a plunger driver removably attachable to the proximal end of the cartridge holder and having a piston rod which engages a plunger on the first cartridge; anda cartridge connector having a proximal end attachable to the distal end of the cartridge holder, a distal end adapted to engage a septum end of the second cartridge, said cartridge connector including a transfer needle and an exhaust needle which extend distally to penetrate the septum end of the second cartridge, wherein the transfer needle extends proximally to penetrate the septum of the first cartridge and the exhaust needle terminates in the sealed interior waste chamber;wherein after use, the plunger driver may be removed from the cartridge holder, the first cartridge removed, and the cartridge holder and plunger cleaned for re-use.2. ...

PLUG FOR CONTAINER

A plug for a container capable of improving air-tightness and liquid-tightness is provided. A plug includes a first split piece having a cylindrical first fitting portion to be mounted on an opening portion of a container body and fitted to an opening portion space of the opening portion, an end wall which blocks one end of the first fitting portion, and a first flange portion extending outwardly in a radial direction of the first fitting portion from the other end thereof; and a second split piece having a second fitting portion which is fitted to the first fitting portion of the first split piece and forms a closed space between the end wall and the second fitting portion and a second flange portion extending outwardly in a radial direction of the second fitting portion therefrom. 1. A plug for a container comprising:a first split piece formed of a flexible and resilient material, the first split piece having a cylindrical fitting portion to be mounted on and fitted to an opening portion of a container body containing liquid, the cylindrical fitting portion provided with an opening formed on one end side thereof and an opening formed on the other end side thereof, an end wall which blocks the opening formed on the one end side, and a first flange portion extending outwardly in a radial direction of the fitting portion from the other end thereof; anda second split piece formed of a flexible and resilient material, the second split piece having a partition wall which blocks the opening formed on the other end side and forms a closed space between the end wall and the partition wall and a second flange portion extending outwardly in a radial direction of the partition wall therefrom.2. The plug for a container of claim 1 ,wherein an absorber formed of a liquid-absorbing material is contained in the closed space.3. The plug for a container of claim 1 ,wherein in the closed space, the end wall of the first split piece and the partition wall of the second split piece ...

DRUG INJECTION APPARATUS AND DRUG CONTAINER

A drug injection apparatus includes a drug container, a needle tube having a first needle tip and a second needle tip, a needle-holding portion which holds the central portion of the needle tube, and a drug container mount from which the second needle tip projects. The drug container has a container body, having a contact portion to be penetrated by the second needle tip and a pressing portion that faces the contact portion, wherein the pressing portion is to be pressed toward the contact portion side so as to deform; a seal member attached to a portion of the contact portion to be penetrated by the second needle tip, and adapted to be brought into close contact with the circumferential surface of the needle tube in liquid-tight manner; and a protective plate adapted to avoid the pressing portion from being penetrated by second needle tip inserted into the container body. 1. A drug injection apparatus comprising:a drug container having a drug filled therein;a needle tube having a first needle tip to be stuck into a living body and a second needle tip to be inserted into the drug container;a needle-holding portion which holds a central portion of the needle tube; anda drug container mount which is arranged on the second needle tip side of the needle-holding portion and from which the second needle tip projects, a container body having a contact portion to be penetrated by the second needle tip and to be brought into contact with the drug container mount, and a pressing portion that faces the contact portion, wherein the pressing portion is to be pressed toward the side of the contact portion so as to deform;', 'a seal member attached to a portion of the contact portion to be penetrated by the second needle tip, and adapted to be brought into close contact with the circumferential surface of the needle tube in a liquid-tight manner; and', 'a penetration avoiding portion adapted to avoid the pressing portion from being penetrated by second needle tip inserted into the ...

Fluid dispenser with tongue depressor

A fluid dispenser contains a fluid and selectively delivers the fluid orally to a subject. The fluid dispenser includes a main body defining a vessel that contains the fluid. The fluid dispenser also includes a dispensing portion that extends from the main body. The dispensing portion defines a passage therethrough that is in fluid communication with the vessel. The passage terminates at a dispenser opening through which the fluid exits the passage and flows into the mouth of the subject. Moreover, the fluid dispenser includes a tongue depressor that extends from the dispensing portion. The tongue depressor is operable to depress the tongue of the subject while the fluid is dispensed into the mouth of the subject.

Multi-Dose Vial and Method

A vial for storing multiple doses of a substance to be dispensed into one or more syringes or other delivery devices. The vial has a body, a variable-volume storage chamber within the body for storing multiple doses of the substance therein, and a one-way valve connectable in fluid communication with a syringe or other delivery device. The one-way valve is moveable relative to the body between first and second positions (i) one of which permits the valve to open so that substance from the variable-volume storage chamber can flow therethrough and into the syringe or other delivery device connected in fluid communication therewith, and (ii) one of which prevents the valve from opening. 1. A device for storing multiple doses of a substance to be dispensed into one or more syringes or other delivery devices , comprising:a body;a storage chamber within the body for storing multiple doses of the substance therein; anda one-way valve connectable in fluid communication with a syringe or other delivery device and moveable between first and second positions, and having a closed position preventing substance from passing therethrough and an open position permitting substance to pass therethrough;wherein, in the first position the one-way valve is prevented from opening into the open position and substance from the storage chamber cannot pass therethrough, and in the second position the one-way valve is permitted to open into the open position so that the one-way valve permits substance from the storage chamber to flow therethrough and into the syringe or other delivery device connected in fluid communication therewith.2. A device as defined in claim 1 , wherein the one-way valve is configured to substantially prevent any fluid flow in a substantially opposite direction claim 1 , from the syringe or other delivery device claim 1 , therethrough claim 1 , and into the storage chamber.3. A device as defined in claim 1 , wherein the storage chamber comprises a variable-volume ...

Sterile Openable Access Port and Containers Including the Same

A connector for providing sterile access to a flexible container is provided that comprises a tubular member having a first portion and a second portion, each of the first portion and the second portion having an open end. The first portion and second portion are joined to each other by a frangible segment, with each of the first portion and the second portion having a gripable surface associated therewith that is configured to facilitate the application of torsional force to the tubular member at the frangible segment. Upon the application of a sufficient amount of torsional force, the frangible segment will break, permitting the first and second portions to be separated from each other. 1. A connector for providing sterile access to a flexible container for receipt of a medical fluid comprising:a tubular member having a first portion and a second portion, each of the first portion and second portion having an open end;the first portion and the second portion joined to each other by a frangible segment;each of the first portion and the second portion having a gripable surface associated therewith configured to facilitate the application of torsional force to the tubular member at the frangible segment; andthe first portion having a seal on the end thereof and the second portion having a pierceable membrane and being configured to have a flexible container attached thereto.2. The connector of in which the gripable surfaces are generally planar and further comprise one or more reinforcing elements.3. The connector of in which the reinforcing elements are raised ribs.4. The connector of any of in which the frangible segment has a reduced wall thickness relative to the first portion and second portion.5. The connector of wherein the second portion includes a radially-outwardly extending flange adjacent the frangible segment and a tubular extension configured to receive a spike extending beyond the flange and having an outside diameter smaller than the inside diameter ...

CHLOROBUTYL RUBBER-BASED SELF-RESEALING SEPTUM AND CLOSURE ASSEMBLY

A self-resealing septum useful in a closure assembly for a container for storing non-aqueous liquids is provided. The septum having a laminate structure including a first layer of a resilient material derived from chlorobutyl rubber and a second layer of a non-elastic polymer. The self-resealing closure assembly includes the septum and a retaining mechanism that is useful for a container assembly that contains a non-aqueous liquid comprising an organic solvent, a liquid organic compound, a water-reactive or oxygen-reactive compound, or a combination thereof. 1. A septum for use in a self-resealing closure assembly for a container containing a non-aqueous liquid , the septum having a laminate structure comprising:a first layer of a resilient material derived from halobutyl rubber and having first and second opposed surfaces, wherein the first layer has a first layer thickness between the first and second opposed surfaces within the range from about 1 mm to about 10 mm; anda second layer of a first non-elastic polymer extending across, and bonded to, the first surface of the first layer, wherein the second layer has a second layer thickness within the range from about 0.03 mm to about 1 mm, wherein the laminate structure of the septum is penetrable by a member in an axial direction and a portion of the laminate structure being configured to elastically distend to pass the member through a tear in the septum and to be self-closing by returning opposite edges of the tear to a substantially contiguous closed condition after withdrawal of the member and which maintains a seal following member penetration in an axial direction and withdrawal, and wherein the septum is used for closing an opening in the container.2. The septum of wherein the first layer is in an initially unbroken condition and the tear is made by rupturing the first layer with the member.3. The septum of further comprising a third layer of a second non-elastic polymer extending across claim 1 , and bonded ...

INSERT AND VIAL FOR THE INFUSION OF LIQUIDS

The invention relates to an insert and a vial for the infusion of a liquid. The vial comprises a hollow body, a grasp portion and a head. The head comprises a delivery opening defining an axis X; a septum for closing the opening; and at least one circumferential push surface next to the head and firmly connected to the grasp portion. The insert is suitable to deliver the liquid and to receive the vial along axis X. The insert comprises a main body with lower ducts, an inner part and a piercing spike. The inner part defines a seat for the vial head, and comprises one slit for engaging the circumferential push surface. The spike is suitable to pierce the vial septum and defines upper ducts. The inner part is able to rotate inside the main body between a fluidly open configuration and a fluidly closed configuration. 1308031803832. Vial () for storing and delivering a liquid () , comprising a hollow body () for storing the liquid () , a grasp portion () and a head () comprising:{'b': '33', 'a delivery opening () defining an axis X,'}{'b': 34', '33, 'a closing septum () suitable for closing the delivery opening (); and'}{'b': 35', '32', '37', '35', '38, 'at least one circumferential push surface () defined next to the head () by a protrusion (), the circumferential push surface () being firmly connected to the grasp portion ().'}230373530383130. Vial () according to claim 1 , wherein the protrusion () defining the circumferential push surface () is integral with a rim of the vial () and wherein the grasp portion () is part of the body () of the vial ().33036373536383130. Vial () according to claim 1 , further comprising a cover () claim 1 , wherein the protrusion () defining the circumferential push surface () is part of the cover () and wherein the grasp portion () is part of the body () of the vial ().430393037353839. Vial () according to claim 1 , further comprising a clip () covering at least part of the vial () claim 1 , wherein the protrusion () defining the ...

VIAL DEVICE AND METHODS

Disclosed are embodiments of a vial device and related systems that can include a cartridge that can have a proximal end and a distal end, where the cartridge can include a housing that defines a fluid chamber. Embodiments of the vial device can include a first stopper, where the first stopper can be positioned at about the proximal end of the cartridge, and a second stopper, where the second stopper can be movable relative to the cartridge. Embodiments of the vial device can include an outer housing, where the cartridge can be configured to seat within the outer housing. 1. A vial device comprising:a. a cartridge having a proximal end and a distal end, the cartridge having a housing that defines a fluid chamber;b. a first stopper, the first stopper being position at about the proximal end of the cartridge;c. a second stopper, wherein the second stopper is movable relative to the cartridge and is positioned at about the distal end of the cartridge;d. an opaque outer housing, the cartridge being configured to seat within the opaque outer housing, wherein the cartridge and the opaque outer housing define a cavity therebetween.2. The vial device of claim 1 , wherein the opaque outer housing is amber colored.3. The vial device of claim 1 , wherein the cartridge is configured to retain a light sensitive drug.4. The vial device of claim 1 , wherein the opaque outer housing further comprises a projection claim 1 , wherein the second stopper is seated on the projection in a first position.5. The vial device of claim 1 , wherein the cavity defined by the cartridge and the opaque outer housing is at least partially filled with a fluid.6. The vial device of claim 1 , wherein the opaque outer housing substantially prevents light from penetrating the cartridge.7. The vial device of claim 1 , wherein the first stopper is configured to be pierced with an injection needle.8. The vial device of claim 1 , wherein the cartridge is a self-regulating pressurized system.9. A vial device ...

MOLECULAR IMAGING VIAL TRANSPORT CONTAINER AND FLUID INJECTION SYSTEM INTERFACE

A pharmaceutical transport container includes a first body portion adapted to receive at least a portion of a pharmaceutical vial, a second body portion removably engaged with the first body portion to fully enclose the vial, and, optionally, a ratcheting mechanism to permit rotation of the cap member relative to the second body portion upon application of rotational force of a predetermined amount. A pharmaceutical transport container may also include, for example, a guide tab extending from an exterior surface of the second body portion to engage a guide slot defined in a fluid injection system docking station, whereby the transport container translates axially and rotationally into the docking station to establish a fluid connection between the vial and a fluid connector mechanism or element disposed within the docking station. 1. A pharmaceutical transport container , comprising:a first body portion adapted to receive at least a portion of a pharmaceutical vial and defining an opening for establishing fluid communication with the vial, and comprising a proximal end;a second body portion engaged with the first body portion to fully enclose the vial, the second body portion having a distal end engaged with the proximal end of the first body portion and a closed proximal end and defining an interior cavity therebetween; andwherein the second body portion is adapted to cooperate with a receiving docking station of a fluid injection system to establish a fluid connection between the vial and a fluid connector element disposed within the docking station as the second body portion is inserted axially into the docking station.2. The pharmaceutical transport container of claim 1 , further comprising at least one guide tab extending radially from an exterior surface of the second body portion or within the docking station claim 1 , the at least one guide tab configured to engage at lease one guide slot defined in the exterior surface of the second body portion or defined ...

DEVICE FOR EXTRACTING, STORING AND/OR PROCESSING BLOOD OR OTHER SUBSTANCES OF HUMAN OR ANIMAL ORIGIN, AND FOR APPLYING BLOOD COMPOUNDS OR OTHER BIOLOGICAL COMPOUNDS

Device (1111) for extracting, storing and/or processing blood or other substances of human or animal origin, and for applying blood compounds or other biological compounds, which comprises a body () inside which a piston () is capable of moving longitudinally and is separable at least in part, where the body () is provided with an internal space () that may be connected to the outside by means of a conduit () at a first end () of the body (), where the body () and the piston () may be blocked longitudinally in at least one position to allow the creation of different degrees of vacuum. The device has multiple uses and is extremely versatile. 111114024134224148650951241342650241549342951342a,b,c,d;. Device () for extracting , storing and/or processing blood or other substances of human or animal origin , and for applying blood compounds or other biological compounds , which comprises a body (; ) inside which a piston (; ) is capable of moving longitudinally , where the body (; ) is provided with a first end (; ) at which a conduit (; ) is provided connecting an internal space (; ) of the body (; ) located between the piston (; ) and the conduit (; ) with the outside of the body (; ) , and a second end (; ) through which the piston (; ) projects outward and which is hermetically separated from the internal space (; ) by means of the piston (; ) , characterised in that:{'b': 3', '42', '3', '42', '2', '41, 'at least part of the piston (; ) is capable of being separated from the rest of the device so that the piston (; ) does not project out of the body (; ),'}{'b': 3', '42', '13', '13', '13', '52, 'i': a', 'b,', 'c;, 'the piston (; ) comprises at least one blocking surface (, ),'}{'b': 2', '41', '14', '14', '14', '53', '13', '13', '13', '52', '3', '42', '3', '42', '3', '42', '4', '48', '3', '42', '5', '49, 'i': a', 'b,', 'c;', 'a,', 'b,', 'c;, 'the body (; ) comprises at least one blocking surface (, ) adapted to come into contact with a blocking surface () of the piston ...

Ready to Drink Container with Nipple and Penetrable and Resealable Portion, and Related Method

A container is provided for storing a product, such as a fat containing liquid product, and includes a body defining a chamber for receiving the product; and a container closure including a sealing portion for sealing the product within the chamber. The container closure includes a member forming a substantially fluid-tight seal between the container closure and the body; a nipple in fluid communication with the chamber that seals the chamber with respect to the ambient atmosphere during storage of the product in the chamber and that can be opened to dispense product from the chamber therethrough; and a needle penetrable and laser resealable portion that is penetrable by the needle for aseptically filling the chamber with the product, and that is thermally resealable by the application of laser radiation thereto to seal the product within the chamber. 1. An apparatus comprising:a container including a body defining a chamber for receiving a product;a container closure including a sealing portion forming a substantially fluid-tight seal between the container closure and the body, and a nipple, wherein the container closure seals the chamber with respect to the ambient atmosphere during storage of the product in the chamber and can be opened to dispense product from the chamber through the nipple; anda penetrable and resealable portion that is penetrable by an injection member for aseptically filling the chamber with the product through the injection member, and a resulting penetration hole is resealable to seal the product within the chamber.2. An apparatus as defined in claim 1 , wherein the nipple includes a sealing member that is movable between a first position sealing the nipple claim 1 , and a second position opening the nipple and allowing product in the chamber to be dispensed therethrough.3. An apparatus as defined in claim 2 , wherein the sealing member is frangibly connected to the nipple such that in the first position the sealing member is connected to ...

CLOSURE CAP FOR RECEPTACLES FOR RECEIVING MEDICAL LIQUIDS AND RECEPTACLE FOR RECEIVING MEDICAL LIQUIDS

The invention relates to a closure cap () for receptacles for receiving medical liquids, in particular receptacles filled with infusion solutions, transfusion solutions or liquids for enteral nutrition. The invention further relates to a receptacle () for receiving medical liquids, in particular a bottle, comprising such a closure cap. The closure cap () according to the invention is characterized by two injection parts ( and ) arranged separately from one another, each for injecting an additive. One injection part () serves to inject an additive with an injection syringe that has a needle (cannula), while the other injection part () serves to inject an additive with a needle-less injection syringe. 1. A closure cap for receptacles for receiving medical liquids , in particular for receptacles filled with infusion or transfusion solutions or liquids for enteral nutrition , with a withdrawal part for withdrawing the medical liquid using a spike , wherein the withdrawal part has an outwardly directed connector part , with a recess for receiving the spike , and an inwardly directed closure part , in which a self-sealing membrane is arranged with which the recess of the withdrawal part is closed , and an injection part separate from the withdrawal part and designed for injecting an additive into the medical liquid using a needleless injection syringe , wherein the injection part has an outwardly directed connector part , with a recess for receiving the conical stem of the syringe , and an inwardly directed closure part , in which a self-sealing membrane is arranged with which the recess of the injection part is closed , wherein the closure cap has a second injection part separate from the first injection part and designed for injecting an additive into the medical liquid using an injection syringe that has a needle , wherein the second injection part has an inwardly directed closure part , with a recess in which a self-sealing membrane is arranged with which the recess ...

Adapter and Drug Cartridge Alignment Device

An alignment device for coupling a liquid drug cartridge with a longitudinal cartridge axis and a constricted neck portion with a cap and a piercable septum distal from the neck portion with an adapter is presented. The septum is perpendicular to the cartridge axis. The device comprises an adapter cannula with a longitudinal cannula axis to pierce the septum and a proximal cartridge engagement structure for axial aligned engagement with a distal end section of cartridge body. The device further comprises a distal adapter engagement structure for axial aligned engagement with the adapter. A coupling of the cartridge with the adapter is enabled via the alignment device. The adapter and the cartridge are, during the coupling, aligned by the cartridge engagement structure and the adapter engagement structure, respectively relative to each other such that the longitudinal cartridge axis and the longitudinal cannula axis form a common longitudinal axis. 1. An alignment device for coupling a liquid drug cartridge having an cartridge body extending along a longitudinal cartridge axis (Z) and , at its distal end , a constricted neck portion and a cap with a piercable septum perpendicular to the cartridge axis (Z) and distal from the neck portion; and an adapter comprising an adapter cannula with a longitudinal cannula axis (Z′) to pierce the septum and an infusion device coupler to mechanically couple to and engage with a housing of an ambulatory infusion device , the alignment device comprising:a proximal cartridge engagement structure designed for axial aligned engagement with a distal end section of the cartridge body; anda distal adapter engagement structure designed for axial aligned engagement with the adapter enabling a coupling of the cartridge with the adapter via the alignment device, wherein the adapter and the cartridge are, during the coupling, aligned by the cartridge engagement structure and the adapter engagement structure respectively relative to each other ...

Fluid Container Devices, Methods and Systems

A drug container assembly for use with a parenteral drug delivery device is disclosed. The container assembly includes a container configured to hold the medication and an intermediate port connector. The port connector may be fixedly coupled to the container and removably coupled to the delivery device in a convenient, reliable, and sealed manner In use, the port connector may convey the medication from the container to the delivery device for delivery to the patient. 1. A delivery port for use with a delivery device , the delivery port comprising:an inlet;an outlet;a pin;a first O-ring; anda second O-ring, wherein the port connector having a sealed configuration in which the first and second O-rings are positioned in sealed engagement with the pin to close the delivery port; an intermediate configuration in which the first O-ring is positioned in sealed engagement with the delivery device and the second O-ring is positioned in sealed engagement with the pin; and a delivery configuration in which the first O-ring is positioned in sealed engagement with the delivery device and the delivery port is positioned in fluid communication with a fluid passageway of the delivery device.2. The delivery port of claim 1 , wherein in the delivery configuration claim 1 , the first and second seals are positioned in sealed engagement with the delivery device.3. The delivery port of claim 1 , wherein in the delivery configuration claim 1 , the first seal is positioned in sealed engagement with the delivery device and the second seal is positioned in sealed engagement with the pin.4. The delivery port of claim 1 , wherein the port connector includes a shoulder that transfers movement of the port connector to the first O-ring.5. The delivery port of claim 4 , wherein the first and second O-rings are positioned on a same side of the shoulder.6. The delivery port of claim 4 , wherein the first O-ring is positioned below the shoulder and the second O-ring is positioned above the ...

DRUG-FILLED SYNTHETIC RESIN AMPULE AND SYNTHETIC RESIN AMPULE BODY USED FOR SAME

A drug-filled synthetic resin ampule includes an ampule body and a drug filled in the ampule body. The ampule body includes a tip-side sealing portion, a hollow portion, and an annular breakable portion provided between the tip-side sealing portion and the hollow portion. The tip-side sealing portion includes a flat plate portion for grasping formed at an upper portion thereof, and an internal ceiling portion exposed to the interior of the hollow portion. The breakable portion includes an annular smallest diameter portion, and the smallest diameter portion is located near an annular circumferential edge portion of the internal ceiling portion and is located above the annular circumferential edge portion of the internal ceiling portion. 1. A drug-filled synthetic resin ampule comprisinga hollow ampule body, a lower-end-side sealing member for sealing a lower end of the ampule body, and a drug filled in the ampule body;wherein the ampule body includes a tip-side sealing portion, a hollow portion located below the tip-side sealing portion and having a drug containing portion therein, and an annular breakable portion provided between a lower portion of the tip-side sealing portion and an upper portion of the hollow portion;the tip-side sealing portion includes a flat plate portion for grasping formed at an upper portion thereof and an internal ceiling portion exposed to an interior of the hollow portion; andthe breakable portion includes an annular smallest diameter portion which is located near an annular circumferential edge portion of the internal ceiling portion and is located above the annular circumferential edge portion of the internal ceiling portion.2. A drug-filled synthetic resin ampule according to claim 1 , wherein the annular smallest diameter portion is an annular smallest diameter portion formed to have an acute angle.3. A drug-filled synthetic resin ampule according to claim 1 , wherein an upper portion of the hollow portion gradually decreases in wall ...

FLEXIBLE PACKAGE WITH A SEALED STERILE CHAMBER FOR THE RECONSITUTION AND ADMINISTRATION OF FLUID MEDICINAL OR NUTRITIONAL SUBSTANCES INSTILLABLE INTO THE BODY OF A PATIENT

A package for infusion or instillation of medicinal or nutritional products into the body of a patient comprises a bag of liquid diluent equipped with at least one drain tube and a mixing tube equipped with a coupling and perforation device for a bottle of a pharmacological or nutritional substance in powder, gel or other material, provided with a perforatable cap. The package comprises a flexible airtight sterile casing, containing said bottle of the substance in powder or other and the coupling and perforation device. The bottle is housed in the casing in a coupling position with the coupling and perforation device and is manually manoeuvrable from the outside of the casing up to a perforating position of the cap of the bottle. 1. A package for infusion or instillation of medicinal or nutritional products into the body of a patient , comprising a bag of liquid diluent equipped with at least one drain tube provided with a closing device , and a mixing tube equipped with an openable closure and which ends with a coupling and perforation device for a bottle of a pharmacological or nutritional substance in powder , gel or other material , provided with a perforatable cap , said package comprising at least a flexible airtight sterile casing , containing said bottle of the substance in powder or other and said coupling and perforation device , said bottle being housed in the casing in a coupling position only with the coupling and perforation device and being manually manoeuvrable from the outside of the casing up to a perforating position of said cap through the same coupling and perforation device , wherein said coupling and perforation device comprises a first element slidably coupled with a second element and movable between said coupling position of the bottle and said perforating position of the cap of the bottle , in which said first element comprises a ring from which at least two flaps equipped with notches suitable to accommodate the bottle in the coupling ...

Adaptor for Coupling with a Medical Container

The invention relates to an adaptor for coupling with a medical container closed by a septum, the adaptor comprising:—a gripping member () for securing the adaptor to the medical container,—a needle access port intended to face an outer surface of the septum,—a pierceable elastomeric piece () having a longitudinal axis located into the needle access port, said pierceable elastomeric piece having a recess () with a proximal opening and an outer wall () in contact with the needle access port,—attaching means for maintaining the elastomeric piece into the needle access port. The invention also relates to an assembly comprising such an adaptor and a medical container, and to the use of such an adaptor for preventing the contamination inside a medical container closed by a septum. 1. An adaptor for coupling with a medical container , said medical container having a collar closed by a septum , said septum having an outer surface directed towards the outside of the medical container , the adaptor comprising:a gripping member for securing the adaptor to the medical container,a needle access port facing the outer surface of the septum when the adaptor is coupled to the medical container, anda pierceable elastomeric piece having a longitudinal axis located into the needle access port, said pierceable elastomeric piece having a recess with a proximal opening, an outer wall in contact with the needle access port, and a distal surface comprising a protruding part engageable with the outer surface of the medical container septum,wherein the elastomeric piece and the needle access port comprise an attaching arrangement for maintaining the elastomeric piece into said needle access port when a pressure is applied by the protruding part on the outer surface of the septum.2. The adaptor according to claim 1 , wherein a ratio between a height of said recess and a width of said recess ranges from 0.3 to 0.7.3. The adaptor according to claim 1 , wherein said recess comprises a bottom ...

TRANSFER SET

A transfer set generally includes an outer sleeve configured for connecting an inner sleeve to a vial such that a passage of the inner sleeve is disposed above a stopper of the vial. The transfer set further includes a cap configured for insertion into the outer sleeve such that the cap is connected to the outer sleeve and is detachable from the outer sleeve via rotation of the cap relative to the outer sleeve. The cap has an interior space and a cam disposed within the interior space, wherein the inner sleeve, and a spike within the inner sleeve, extend into the interior space when the cap is connected to the outer sleeve, and wherein, as the cap rotates relative to the outer sleeve for detachment of the cap from the outer sleeve, the cam interacts with the follower to translate the spike toward the stopper for puncturing the stopper. 1. A transfer set for transferring liquid into or out of a vial sealed by a stopper , the transfer set comprising:an inner sleeve comprising a passage extending through the inner sleeve along a longitudinal axis;an outer sleeve configured for connecting the inner sleeve to the vial such that the passage is disposed above the stopper of the vial;a spike comprising a follower, wherein the spike is disposed within the passage of the inner sleeve and is configured for longitudinal translation along the passage to puncture the stopper; and a closed top wall;', 'an annular side wall extending from the closed top wall to define an open bottom and an interior space of the cap; and', 'a cam disposed within the interior space,, 'a cap configured for insertion into the outer sleeve such that the cap is connected to the outer sleeve and is detachable from the outer sleeve via rotation of the cap relative to the outer sleeve, the cap comprisingwherein the inner sleeve and the spike extend into the interior space when the cap is connected to the outer sleeve, andwherein, as the cap is rotated relative to the outer sleeve for detachment of the cap ...

PERFORATING NEEDLE FOR FLASK WITH SEPTUM

A perforating needle intended to be inserted into a flask through a stopper or septum to inject and remove a fluid includes a pointed end for piercing the stopper and a cylindrical body. The central body includes a central channel through which the fluid may enter and leave the flask and a side wall having at least one lateral orifice. The orifice is in fluid communication with the central channel. A lower end of the orifice is, in use, essentially level with an inner face of the stopper. The orifice is extended toward the pointed end by at least one slot, a shape of which is essentially tangential to a flow of the fluid so as to channel the fluid along an axis of the needle. The side wall includes at least two diametrically opposite lateral orifices arranged on either side of a central island. 1. A perforating needle intended to be inserted into a flask through a stopper or septum to inject and remove a fluid , the needle comprising:a pointed end configured to pierce the stopper; anda cylindrical body comprising a central channel through which the fluid may enter and leave the flask and a side wall comprising at least one lateral orifice, the orifice being in fluid communication with the central channel and a lower end of the orifice being, in use, essentially level with an inner face of the stopper, the orifice being extended toward the pointed end by at least one slot, a shape of which is essentially tangential to a flow of the fluid so as to channel the fluid along an axis of the needle,wherein the side wall comprises at least two diametrically opposite lateral orifices arranged on either side of a central island, the central island having a separating rim forming an angle of between 15° and 60°,wherein the separating rim penetrates the central channel, andwherein the slots extending the orifices emerge near the pointed end.2. (canceled)3. The perforating needle according to claim 1 , wherein the perforating needle is comprised of rigid plastic material.4. The ...

PRESSURE-REGULATING VIAL ADAPTORS

A vial adaptor can include a connector interface and/or a piercing member. The vial adaptor can include a regulator assembly. The regulator assembly can include a regulator base, a regulator nest coupled with the regulator base, and/or a storage chamber formed at least partially by one or both of the regulator base and regulator nest. The regulator assembly can include a cover connected to one or both of the regulator base and regulator nest and fitted around a radially outward portion of one or both of the regulator base and regulator nest. In some cases, the regular assembly includes a flexible enclosure connected to the regulator nest and configured to transition between a contracted configuration and an expanded configuration. In some cases, the flexible enclosure is inhibited from transitioning to the expanded configuration prior to removal or modification of the cover from the regulator assembly. 1. A pressure-regulating vial adaptor comprising:a connector interface;a piercing member in communication with the connector interface; and a storage chamber;', 'a flexible enclosure positioned within the storage chamber in a contracted configuration and configured to expand in an expanded configuration;', 'an expansion inhibitor connected to a portion of the regulator assembly, the expansion inhibitor comprising one or more weakened portions configured to facilitate a tear in the expansion inhibitor when the flexible enclosure moves from the contracted configuration to the expanded configuration., 'a regulator assembly comprising2. The vial adaptor of claim 1 , wherein at least one of the one or more weakened portions is a perforation.3. The vial adaptor of claim 1 , wherein the expansion inhibitor extends over at least a portion of a side of the regulator assembly.4. The vial adaptor of any of claim 1 , wherein the expansion inhibitor includes an aperture when the flexible enclosure is in the contracted configuration.527.-. (canceled)28. A method of manufacturing a ...

PHARMACEUTICAL PRODUCT CONTAINER WITH PERMANENT LOCKING MECHANISM

Various embodiments of pharmaceutical product containers are disclosed. Each pharmaceutical product container includes a cap, a container body, and a locking mechanism. The locking mechanism is disposable from a locked state to an unlocked state at least when the cap is in a closed position relative to the container body (e.g., to define an enclosed space for pharmaceutical product). Once in the locked state and with the cap being in a closed position, the locking mechanism is unable to return to its unlocked state. Pharmaceutical product enclosed within the container with the locking mechanism being in its locked state may then be disposed of in any appropriate manner (e.g., discarded in the trash). 1. A pharmaceutical product container , comprising:a cap comprising a cap body;a container body; anda locking mechanism disposable from an unlocked state to a locked state at least when said cap is in a closed position, with said cap body remaining in a fixed position relative to said container body, and by moving said locking mechanism relative to said cap body, wherein said locking mechanism is unable to return to said unlocked state from said locked state with said cap being in said closed position, and wherein said cap is repeatedly movable relative to said container body between said closed position and an open position prior to said locking mechanism being disposed in said locked state.2. The pharmaceutical product container of claim 1 , wherein said cap comprises said locking mechanism.3. The pharmaceutical product container of claim 1 , wherein said container body comprises at least one locking segment claim 1 , wherein said cap comprises a first locking tab claim 1 , wherein said first locking tab is disposable in an unlocking position where said first locking tab and said at least one locking segment are misaligned claim 1 , and wherein said first locking tab is disposable in a locking position where said first locking tab and said at least one locking segment ...

TRANSFER DEVICE FOR MEDIA, COMPRISING A NON-RELEASABLY LOCKABLE ADAPTER

A transfer device () for removing or transferring a medium out of or into a bottle () having a bottle neck () that can be closed by means of a closure (), including a first adapter part (), which can be positioned on the bottle, and a second adapter part (), which interacts with the first adapter part, which can be displaced in the longitudinal direction of the bottle, and has a conducting element () for piercing the closure. After the second adapter part () has been displaced along the first adapter part in the direction of the closure () and the second adapter part has been locked, the first adapter part () is non-releasably fastened to or around the bottle (). 139.-. (canceled)4010100200400203442. A transfer device ( , , , ) for the withdrawal or delivery of a medium out of or into a bottle () with a neck () , that is sealable by a closure () , comprising:{'b': 12', '112', '212', '412, 'a first adapter component (, , , ) that can be positioned on the bottle, and'}{'b': 14', '114', '214', '414', '50, 'a second adapter component (, , , ), which interacts with the first adapter component, is moveable in the longitudinal direction of the bottle, and comprises a delivery element () for piercing the closure,'}{'b': 14', '114', '214', '414', '12', '112', '212', '412', '42', '20, 'wherein, after moving the second adapter component (, , , ) along the first adapter component (, , , ) in the direction of the closure () and locking of the second adapter component, the first adapter component is secured in position non-detachably at the bottle () or around the bottle,'}{'b': 10', '100', '200', '400', '20', '12', '112', '212', '412', '14', '114', '214', '414', '42, 'wherein the transfer device (, , , ) is secured in position at or around the bottle (), the first and the second adapter components (, , , ; , , , ) form an enclosed sealed envelope that surrounds the bottle at least in the area of the closure element (),'}{'b': 14', '214', '44', '46', '50, "the second adapter ...

RUBBER STOPPER FOR MEDICINE CONTAINER AND MEDICINE-ACCOMMODATED MEDICINE CONTAINER USING THE SAME

A rubber stopper for a medicine container has a rubber stopper body and a coating layer directly applied to a surface exposed in the medicine container. The coating layer is more flexible than a forming material of the rubber stopper body. The said coating layer comprises a composition containing a silicone-based resin which comprises a condensate of a reactive silicone having a terminal silanol group, and wherein the condensate contains a siloxane bond derived from the silanol group. 1. A rubber stopper for a medicine container comprisinga rubber stopper body and a coating layer directly applied to a surface of said rubber stopper body exposed in said medicine container,wherein said coating layer is more flexible than a forming material of said rubber stopper body andsaid coating layer comprises a composition containing a silicone-based resin which comprises a condensate of a reactive silicone having a terminal silanol group, and wherein said condensate contains a siloxane bond derived from said silanol group.2. A rubber stopper for a medicine container according to claim 1 , wherein said reactive silicone is polydimethylsiloxane having said end silanol group.3. A rubber stopper for a medicine container according to claim 1 , wherein said reactive silicone has said silanol group at both ends thereof.4. A rubber stopper for a medicine container according to claim 1 , wherein said composition contains a second silicone compound different from said silicone-based resin having said siloxane bond.5. A rubber stopper for a medicine container according to claim 1 , wherein said composition contains alkylalkoxysilane claim 1 , phenylalkoxysilane claim 1 , aminoalkylalkoxysilane or glycidoxyalkylalkoxysilane as a second silicone compound different from said silicone-based resin having said siloxane bond.6. A rubber stopper for a medicine container according to claim 1 , wherein said composition contains alkylalkoxysilane or phenylalkoxysilane as a second silicone compound ...

Adaptor for Coupling to a Medical Container

An adaptor for coupling with a medical container having a collar closed by a septum including: a tubular body closed at a distal end with a transversal wall from which extends a hollow spike, and at a proximal end by a pierceable elastomeric piece including a cavity having a plurality of circumferentially distributed chambers, each chamber being connected to the hollow spike by a radial channel, the tubular body further receiving an intermediate piece including a plurality of through holes aligned on the chambers, a selecting member having a closure wall provided with one opening, capable of rotating so that the opening is successively aligned with each of the through holes, and a gripping member for securing the adaptor to the medical container. Also, an assembly including the adaptor and a medical container. 1. An adaptor for coupling with a medical container having a collar closed by a septum , said septum having an outer surface directed towards an outside of the medical container , the adaptor comprising:a tubular body substantially closed at a distal end with a transversal wall provided with a central hole from which extends a hollow spike in a distal direction for passage of a fluid, a plurality of circumferentially distributed chambers extending from said transversal wall in a proximal direction, said chambers being closed at a proximal end by a pierceable elastomeric piece, each chamber being connected to said hollow spike by a radial channel provided with a closure member, said closure member being capable of transitioning from a locked state, in which it closes the radial channel, to an open state in which it does not close said radial channel, each chamber being filled with decontaminated air and each closure member being in a locked state in a storage state of said adaptor,said tubular body further receiving an intermediate piece located proximally with respect to said pierceable elastomeric piece, said intermediate piece comprising a plurality of ...

Adaptor for Coupling with a Medical Container

An adaptor for coupling with a vial having a collar closed by a septum, the septum having an outer surface directed towards the outside of the vial, the adaptor comprising: a gripping member for securing the adaptor to the vial, the gripping member being capable of being laterally mounted on the collar of the vial and a pierceable elastomeric piece having at least a part intended to be in contact with the outer surface of the septum when the adaptor is secured on the vial. Also, an assembly including such an adaptor and a vial. 1. An adaptor for coupling with a medical container having a collar closed by a septum , said septum having an outer surface directed towards the outside of the medical container , the adaptor comprising:a gripping member for securing the adaptor to the medical container, said gripping member being capable of being laterally mounted on the collar of said medical container,a pierceable elastomeric piece having at least a part intended to be in contact with the outer surface of the septum when said adaptor is secured on said medical container.2. The adaptor of claim 1 , wherein the surface of said part of the pierceable elastomeric piece is complementary to the whole outer surface of the septum.3. The adaptor of claim 1 , further comprising a compressive member for pressing said pierceable elastomeric piece onto said outer surface of the septum claim 1 , when said adaptor is secured on said medical container claim 1 , said compressive member being capable to transition from an inactive state claim 1 , in which it does not exert pressure on said pierceable elastomeric piece claim 1 , to an active state claim 1 , in which it exerts pressure.4. The adaptor of claim 1 , further comprising a fixing system for preventing releasing of said gripping member and definitively securing the adaptor on said medical container.5. The adaptor of claim 1 , further comprising a transversal wall connected to said gripping member claim 1 , said transversal wall ...

Adaptor for Coupling to a Medical Container

An adaptor for coupling with a medical container, including: a tubular body receiving a pierceable elastomeric piece, defining an inner cavity of the adaptor, the pierceable elastomeric piece being movable within the tubular body between a first position, in which a distal part of the pierceable elastomeric piece forms a seal of the cavity, and a second position, proximally spaced from the first position, in which the distal part opens the seal of the cavity, an air inlet, a filtering system for filling the inner cavity with decontaminated air, and a gripping member for securing the adaptor to the medical container. Also, an assembly comprising such an adaptor and a medical container. 1. An adaptor for coupling with a medical container having a collar closed by a septum , said septum having an outer surface directed towards an outside of the medical container , the adaptor comprising:a tubular body substantially closed at a distal end with a transversal wall provided with a central hole and substantially closed at a proximal end by a pierceable elastomeric piece, said pierceable elastomeric piece, transversal wall and tubular body together defining an inner cavity of said adaptor, said pierceable elastomeric piece being movable within said tubular body between a first position, in which a distal part of said pierceable elastomeric piece forms a seal of said central hole, and a second position, proximally spaced from said first position, in which said distal part opens the seal of said central hole,an air inlet for allowing air from the outside to enter said inner cavity at least when said pierceable elastomeric piece moves from the first position to the second position, said air inlet comprising a filtering system for decontaminating said entering air before it reaches said inner cavity, anda gripping member for securing the adaptor to the medical container, so that a distal surface of said transversal wall is brought in contact with the outer surface of said septum ...

PILL CAP APPARATUS AND METHOD OF USE

A pill cap apparatus and method of use is disclosed herein. The pill cap attaches to bottles and containers to aid in patient compliance with a dosage regimen using solid dosage units of medicine such as pills, capsules and tablets. 1. A pill cap apparatus comprising:a circular enclosure rotatable about a central axis and a circular disc rotatably disposed on the top of the circular enclosure, wherein a space is provided between the circular enclosure and the circular disc, such that the circular disc may rotate on top of the circular enclosure;the circular enclosure includes a raised portion, and the circular disc including an interior space, such that the raised portion is rotatable within the interior space;the circular enclosure includes a plurality of indicators on the top surface of the raised portion to indicate to the user which day or time remains to take a pill or medication;the interior space includes an inner ridge and the raised portion includes an outer ridge, such that the circular disc rotate about the raised portion in a fixed manner;the inner ridge includes a diameter larger than the diameter of the outer ridge of the raised portion;the circular disc includes a height that is greater than a height of the raised portion;the circular enclosure includes an interior threaded surface such that the circular enclosure is rotatably secured to top of a bottle; andwhen the user pushes downward on the circular enclosure to rotate the child proof locking mechanism on the bottle, the circular disc is rotatably displaced from the a displayed indicator through a window on the circular disc as to move to a next indicator.2. The pill cap apparatus of claim 1 , wherein the circular disc includes a circular exterior surface and the circular enclosure includes a circular exterior surface; wherein the circular exterior surface includes a plurality of peaks and troughs.3. The pill cap apparatus of claim 2 , wherein the interior threaded surface includes a secure ...

CONTAINER AND CAP FOR A BIOLOGICAL SPECIMEN

A container for collecting a biological specimen is provided that includes a peripheral wall extending from a base. The container further includes a longitudinal tower disposed within the container. The tower forms a partition within the container to form at least a first chamber and a second chamber therein, wherein the first and second chambers are in fluid communication with one another. In addition, the container includes an insert disposed within the container opposite the base, the insert comprising at least a first opening and a second opening. The second opening provides access to the second chamber and is further configured to engage a specimen collecting device to leave a portion of the specimen collecting device within the second chamber. The first opening provides access to the first chamber and is further configured to receive a syringe therein for accessing the biological specimen. Associated systems and methods are also provided. 125-. (canceled)26. A method for collecting a biological specimen , the method comprising:obtaining a biological specimen with a specimen collection device; and a peripheral wall extending from a base, the peripheral wall and base defining an interior surface and an exterior surface;', 'a longitudinal tower disposed within the container, wherein the longitudinal tower forms a partition within the container to form at least a first chamber and a second chamber therein, wherein the first and second chambers are in fluid communication with one another; and', 'an insert placed over and spanning the tower, wherein the tower defines a separation between a first portion of the insert over the first chamber and a second portion of the insert over the second chamber, wherein the first portion of the insert is not in fluid communication with the second portion of the insert, and wherein the specimen collection device is received by the second chamber., 'inserting the specimen collection device into a container comprising27. The method ...

MULTI-MIX INFUSION BAG

A multi-mix infusion bag is provided. The multi-mix infusion bag includes a lower portion and an upper portion. The lower portion has a lower chamber and the upper portion includes a plurality of chambers. Each chamber is separated and contains a fluid agent. The multi-mix infusion bag is configured to transfer each fluid agent within each chamber of the upper portion into the lower chamber for mixing. The multi-mix infusion bag may include dispensing devices associated with each chamber, wherein the dispensing devices operate to transfer the fluid agents into the lower chamber for mixing.

SMART CONNECTION INTERFACE

A method and apparatus for a connection interface between a reservoir or syringe, infusion set tubing, and an infusion pump is provided. The reservoir, a base and a cap are connected to form an integrated unit that is capable of being inserted and secured in an infusion pump housing. The cap and the infusion pump are each provided with at least one sensor or at least one detectable feature, arranged to interact with at least one corresponding detectable feature or sensor on the other of the cap and infusion pump device, to detect one or more of the presence, position or other characteristic of the cap when the cap is aligned or coupled with the infusion pump housing. The detectable feature and sensor may be magnetic, RF, mechanical, optical or any combination.

CHILDPROOF SAFETY CAP AND ASSOCIATED CONTAINER FOR LIQUID OR PASTY SUBSTANCES

Childproof safety cap having two opposite bead-like threads on its inner wall. Each thread has a widened end region, a stop surface thus being formed. The associated bottle has two opposite groove-like threads on a connecting piece of said bottle, each of which threads has a widened region in the end region, an undercut thus being formed in the groove by the widened region. When the safety cap is screwed on, the stop surfaces on the two bead-like threads hook in behind the undercuts on the groove-like threads. The stop surfaces can be released from each other only if the safety cap is pressed down toward the bottle onto the connecting-piece neck. Connecting-piece neck forms a slipping surface that conically expands downwards. The safety cap can then be unscrewed while simultaneously being rotated. 1196156156196715871171551171881881819. A child-resistant protective cap having an associated container or bottle for liquid or pasty media , equipped with a closure or an application system for said media , characterized in that the protective cap () and the bottle () are each equipped with at least one thread ( , ) , which engage each other by one thread () being outwardly protrudingly shaped and the other thread () being recessed in a groove-like manner , and wherein at the lower end of the thread () on the protective cap () or bottle () there is configured on the protruding thread () a widened region () which is screwable in the groove-like thread () along the same and at its back end forms a stop face () , and wherein said widened region () , in the end position of screwing on the protective cap () , engages a wider region () in the groove-shaped thread () on the bottle () or protective cap () , which wider region () forms an undercut () , so that the stop face () on the protruding thread catches behind the undercut () , and the stop face () is squeezable under the undercut () only by pressing the protective cap () toward the container or the bottle () with slight ...

Container for a mixing system, mixing system for parenteral nutrition, and method for mixing

Container for a mixing system being filled with liquid parenteral nutrition and comprising a male connector and a female connector. The male connector is placed on the opposite side of the container compared to the female connector and the male connector and the female connector are embodied to be mechanically engageable with each other and to engage a mechanical connection with a male connector or a female connector respectively of another container and to form a channel, which enables the passage of liquid. At least two containers form a modular system for parenteral nutrition.

TWO-COMPONENT-MIXING PREFILLED SYRINGE KIT

In a two-component-mixing prefilled syringe kit for preparing an injection solution by mixing a drug component in a syringe barrel and a liquid component in a container, when the injection needle pierced on the seal member of the container outlet is pulled out after preparation of the injection solution, a leak to the outside of the remaining liquid in the container is effectively prevented. 1. A two-component-mixing prefilled syringe kit , comprising;a syringe barrel in which an injection needle is attached to one end, a plunger is slidably inserted from an opening of the other end, and a solid component or a liquid component constituting an injection solution is filled inside;a container in which an outlet is sealed with a seal member that can be pierced by the injection needle, and a liquid component constituting the injection solution is filled inside;a holding member for holding at least one of the syringe barrel or the container so as to be movable along the barrel axis direction of the syringe barrel with the tip of the injection needle facing the outlet of the container;wherein, it is characterized that a space-forming body which forms a space facing the surface of the seal member with a space sealed from the outside is arranged so as to be in close contact with the surface of the seal member, and the space-forming body is formed of a material which can be pierced by the injection needle at a portion facing the tip of the injection needle along the barrel axis direction of the syringe barrel.2. The two-component-mixing prefilled syringe kit as defined in claim 1 , wherein;a volume of a space surrounded by the surface of the seal member and the space-forming body is in the range of 0.001 ml to 0.03 ml.3. The two-component-mixing prefilled syringe kit as defined in claim 1 , further comprising:a needle cap which is formed of a material that can be pierced by the injection needle to cover the injection needle from the tip side, and fixed at base end side to a ...

VIAL PUCK SYSTEM FOR AUTOMATIC DRUG COMPOUNDER

A vial puck configured for attachment to a vial containing a drug is provided. The vial puck includes various features for facilitating uniform control of vials of various sizes in an automatic compounder system. The vial puck features may include a vial recess for receiving a vial of a particular size and securing the vial within the vial recess. The features may also include a cylindrical central portion, perpendicular extensions that extend from a top of the cylindrical central portion, a gear extending from the cylindrical central portion, and a sealing member disposed in the cylindrical central portion. The vial puck may include a cylindrical protrusion configured to press against a septum of the vial to form a seal between the vial puck and the vial. The sealing member may be configured to receive a needle of the compounder system therethrough to allow access to the vial. 1. A method , comprising:providing a vial puck on a vial containing a drug;providing the vial puck in a vial puck recess in a vial tray of a compounder system;rotating the vial tray to move the vial and vial puck to a first position;grasping the vial puck with vial calipers of the compounder system;lifting the vial puck and vial out of the vial tray with a vial lift coupled to the vial calipers; andlifting the vial puck and vial to compress a needle housing of the compounder system to expose a needle assembly and to extend the needle assembly through sealing members of the vial puck and the needle housing into the vial.2. The method of claim 1 , further comprising claim 1 , before lifting the vial puck and vial out of the vial tray:rotating the vial tray to move the vial and vial puck to a second position;engaging a gear of the vial puck with a gear of the compounder system; androtating the vial using the engaged gears of the vial puck and the compounder system.3. The method of claim 2 , further comprising:providing a diluent into the vial via the needle assembly;while grasping the vial puck ...

CONTAINER SYSTEM

A container system having connection devices for establishing a fluid connection between the containers. In one aspect, a connection device comprises a thin point that, within its shape, has a tip between two at least substantially straight legs and wherein the other connection device has a ram with a splitting device that is designed and arranged such as to rupture said thin point by acting on the tip when the containers are coupled. In another aspect, the thin point surrounds the ram, and in a third aspect the connection devices have corresponding, similar thin points, closure elements and splitting devices. In further aspects, the connection devices are similar, and the connection devices are linearly guided. 1. Container system comprising at least two containers each forming an inner chamber ,the containers each comprising a connection device being initially closed, specifically a first connection device of a first container and a second connection device of a second container, andthe connection devices being able to be coupled together such that the coupling produces a continuous fluid connection that is closed off from the surroundings and interconnects the inner chambers of the containers such that contents that can be held in the inner chambers can be mixed,the first connection device comprising a thin point designed to rupture through the application of force by a ram of the second connection device, as a result of which the fluid connection can be established, andwherein in its shape, the thin point comprises a tip between two at least substantially straight legs and the ram comprises a splitting device that is designed and arranged such as to rupture the thin point by acting on the tip when the coupling is produced.2. Container system according to claim 1 , wherein straight claim 1 , aligned portions of the thin point adjoin different sides of the ram.3. Container system according to claim 2 , wherein the aligned portions of the thin point form a film ...

Transfer Set with Floating Needle for Drug Reconstitution

An adapter assembly for establishing bidirectional fluid connection between a cartridge and a vial includes a housing having an open first end adapted to engage the cartridge and a second open end adapted to engage the vial. The adapter includes a needle assembly having a first tip and a second tip, with the needle assembly disposed within the housing and at least partially supported by a needle holder. The needle assembly is movable relative to the housing from an initial position in which the first and second tip are isolated from the cartridge and vial, to an end of use position, in which first tip is engaged with the vial and the second tip is engaged with the cartridge, establishing fluid communication therebetween. The needle assembly is maintained in the initial position by a locking structure which is released by rotationally advancing the needle holder relative to the housing. 1. An adapter assembly for establishing bidirectional fluid connection between a cartridge and a vial comprising:a housing having an open first end adapted to engage the cartridge and a second open end adapted to engage the vial; anda needle assembly having a first tip and a second tip, the needle assembly disposed within the housing and at least partially supported by a needle holder, the needle assembly movable relative to the housing from an initial position in which the first tip and the second tip are isolated from both the cartridge and the vial, to an end of use position, in which first tip is engaged with the vial and the second tip is engaged with the cartridge, thereby establishing fluid communication between the cartridge and the vial,wherein the needle assembly is maintained in the initial position by a locking structure which is released by rotationally advancing the needle holder relative to the housing, thereby releasing the needle holder and allowing the needle holder to move axially within the housing.2. The adapter assembly of claim 1 , wherein in the end of use ...

Combination Medicine Containers and Dispensers

Combination medicine containers and dispensers are shaped similar to or generally the same as standard prescription medicament containers but are configured to dispense one medicament at a time through easy manipulation of integral dispensing means. Each combination medicine container and dispenser has a bottle, a cap, and an integral dispensing mechanism that cooperate with one or more structures of the bottle and/or cap to dispense one medicament at a time from the container. In one form, the combination medicine container and dispenser is designed to allow a user to dispense a single medicament through properly applied pressure. In another form, rotation of one or more components provides dispensing of a single medicament.

LIQUID TRANSFER DEVICES FOR USE WITH INTRAVENOUS (IV) BOTTLES

A liquid transfer device is provided having a trifurcated body that includes a vial adapter at a first end configured to telescopically mount on the crown of an IV bottle to puncture a stopper in the crown with a cannula, an IV port extending from an opposing second end of the trifurcated body, and a needleless self-sealing port extending from a third end of the trifurcated body and configured to couple with the male connector of an additive transfer device. Methods of using the liquid transfer device with an IV bottle, additive transfer device, and an infusion set to prepare an infusion liquid for administration to a patient are also provided. 1. A liquid transfer device for use with an intravenous (IV) bottle , an additive transfer device and an infusion set with an IV spike for intravenous administration of infusion liquid to a patient ,the IV bottle including a closed end IV bottle container tapering towards an open IV bottle neck and containing infusion liquid, and an IV bottle crown mounted on the IV bottle neck and having an IV bottle stopper for sealing the IV bottle,the additive transfer device having a male connector,the liquid transfer device having a longitudinal liquid transfer device centerline and comprising:a) a vial adapter having a transverse vial adapter top surface and a downward depending vial adapter skirt configured to telescopically mount on the IV bottle crown, said vial adapter having a cannula configured to puncture the IV bottle stopper for fluid communication with the IV bottle container upon mounting on the IV bottle crown,said transverse vial adapter top surface having an upright nipple oppositely directed with respect to said cannula,said nipple having a first nipple section with a first nipple section lumen in fluid communication with a cannula lumen of said cannula, andsaid nipple having a second nipple section with a second nipple section lumen in fluid communication with said cannula lumen;b) an IV port extending from said first ...

RUBBER STOPPER FOR DRUG CONTAINER, DRUG-ACCOMMODATING DRUG CONTAINER, AND DRUG CONTAINER SET

A rubber stopper includes: a main body; and a cylindrical container insertion portion extending downward from a lower surface of the main body and configured to fit into a neck portion of a drug container. The main body includes a peripheral edge portion that is disposed on a radially outer side of the container insertion portion and that is configured to abut on an upper surface of an opening portion of the drug container when attached to the drug container. The container insertion portion includes: an outer surface portion that is configured to annularly contact an inner surface of the neck portion, an upper inner surface portion that forms a columnar gap portion, and at least one inclined surface extending obliquely downward toward the outer surface portion of the container insertion portion. 1. A rubber stopper configured to be attached to a drug container that comprises a cylindrical body portion comprising a closed lower end and accommodating a drug therein , and a cylindrical neck portion extending upward from an upper end of the body portion and comprising an opening portion formed at an upper end thereof , an inner diameter of the neck portion being smaller than an inner diameter of the body portion and being substantially constant , the rubber stopper comprising:a main body; anda cylindrical container insertion portion extending downward from a lower surface of the main body and configured to fit into the neck portion of the drug container,wherein the main body comprises a peripheral edge portion that is disposed on a radially outer side of the container insertion portion and that is configured to abut on an upper surface of the opening portion when attached to the drug container, an outer surface portion that is configured to annularly contact an inner surface of the neck portion of the drug container in a liquid tight manner when the rubber stopper is attached to the drug container,', 'an upper inner surface portion that forms a columnar gap portion ...

Sterile Solutions Product Bag

A sterile solution product bag includes sterilization grade filter integrated directly into the product bag such that microbial and particulate matter filtration can be performed using the filter directly at the point of fill. The filter can include a hollow fiber filter membrane contained in a stem connected to a bladder of the product bag. 1. A sterile solution product bag comprising:a bladder;a stem having an inlet end and an outlet end, the outlet end of the stem fluidly connected to the bladder; anda filter disposed in line with the stem, the filter having a filter membrane with a nominal pore size in a range of approximately 0.1 μm to approximately 0.5 μm, wherein the filter membrane is shaped as a hollow fiber with pores residing in the wall of the fiber, wherein the outlet end of the hollow fiber of the filter membrane is sealed and the inlet end is an open inlet.2. The sterile solution product bag of claim 1 , wherein the filter membrane is disposed inside of the stem between the inlet and outlet ends.3. The sterile solution product bag of claim 1 , wherein the filter comprises a plurality of filter membranes4. The sterile solution product bag of claim 1 , wherein the filter membrane has a wall thickness in the range of approximately 150 μm to approximately 500 μm.5. The sterile solution product bag of claim 1 , wherein the filter membrane has a longitudinal dimension in the range of approximately 3 cm to approximately 20 cm claim 1 , an inner diameter in the range of approximately 2 mm to approximately 4 mm claim 1 , and an outer diameter in the range of approximately 2.3 mm to approximately 5 mm.6. The sterile solution product bag of claim 1 , wherein the filter membrane is made of at least one of the following materials: a polyolefin claim 1 , polyvinylidene fluoride claim 1 , polymethylmethacrylate claim 1 , polyacrylonitrile claim 1 , polysulfone claim 1 , polyethersulfone claim 1 , and a polymer containing cationic charges.7. The sterile solution ...

MODULAR DOSING ASSEMBLY OF MEDICAL SUBSTANCES

Systems, devices and methods to establish fluid communication between vessels. Containers and devices having a unitary multiple entry port structure and a port unitary cover with buttons or levers for the assembly of customized final dosages of injectable beneficial substances. Containers and devices having a protective port with a cover configured to hermetically seal second container(s) within the protective port. A vessel having at least two entry ports and at least one exit port, and at least one container containing a dosing regimen, the at least one container configured to be received by one of the at least two entry ports of the vessel, whereby upon connection of the at least one container to the one of the at least two entry ports of the vessel, the dosing regimen in the at least one container is transferred into the vessel. Modular dosing system for adding at least one amount of a medicament to a preparation in a modular construction. System for displaying a dosing regimen or single amount of a medicament, so that the administrator of the amount is able to precisely ascertain the amount administered to a patient. 1. A system for intermixing beneficial substances , comprising:a first container having a unitary multiple entry port structure, the unitary multiple entry port structure configured to receive a plurality of containers and fully engulf thereof, the unitary multiple port structure further comprising a cover configured to seal the plurality of the containers inside the unitary multiple entry port structure, thereby providing a protective entry port structure; anda plurality of containers containing a beneficial substance, the plurality of the containers configured to enter inside the unitary multiple entry port structure,wherein upon entry of the plurality of the containers inside the unitary multiple entry port structure, the plurality of the containers are completely enclosed inside the unitary multiple entry port structure thus providing for leak- ...

RFID CAPS AND LIDS

The present invention relates to an RFID cap for a cryogenic vial, the RFID cap comprising a cap body; and an RFID tag attached to the cap body, the RFID tag comprising an RFID chip and an antenna connected to the chip. The present invention also relates to an RFID box lid for a cryogenic vial storage box having an array of storage slots capable of receiving cryogenic vials; the RFID box lid comprising: a box lid body; and an array of RFID tags positioned on the box lid such that when the box lid is located on the storage box, each RFID tag in the array is aligned with a storage slot in the box. 1. An RFID box lid for a cryogenic vial storage box having an array of storage slots capable of receiving cryogenic vials; the RFID box lid comprising:a box lid body; andan array of RFID tags positioned on the box lid such that when the box lid is located on the storage box, each RFID tag in the array is aligned with a storage slot in the box.2. The RFID box lid of claim 1 , wherein the array of RFID tags is a 10×10 array.3. The RFID box lid of claim 1 , wherein adjacent RFID tags in the array have a centre-to-centre spacing which is no more than 25 mm.4. The RFID box lid of claim 3 , wherein adjacent RFID tags in the array have a centre-to-centre spacing which is no more than 13 mm.5. The RFID box lid of claim 1 , wherein each RFID tag of the array is directly mounted onto the box lid body.6. The RFID box lid of claim 1 , wherein each RFID tag of the array is mounted on a film; and wherein the film attaches the array to the box lid body.7. A film comprising an array of RFID tags for use in the RFID box lid of .8. The film of claim 7 , wherein the array of RFID tags is a 10×10 array.9. The film of claim 6 , wherein adjacent RFID tags in the array have a centre-to-centre spacing which is no more than 25 mm.10. The film of claim 9 , wherein adjacent RFID tags in the array have a centre-to-centre spacing which is no more than 13 mm.11. An RFID cap for a cryogenic vial claim 9 , ...

DRUG CONTAINER CONNECTOR AND MALE MEMBER COVER

A drug container connector () is provided with a puncture needle () capable of puncturing a plug () that seals a mouth () of a container (); and a cover () that covers an opening, on a tip side, of a flow channel () formed in the puncture needle (). The puncture needle () is configured to penetrate the cover () and puncture the plug (). The puncture needle () is provided on a connector main body (). The cover () is held by a slider (). The slider () is movable with respect to the connector main body () in a longitudinal direction of the puncture needle (). The slider () is provided with claws () capable of engaging with a flange () at the mouth of the container (). 1. A drug container connector comprising:a puncture needle capable of puncturing a plug that seals a mouth of a container; and a cover that covers an opening, on a tip side, of a flow channel through which liquid flows and that is formed in the puncture needle, the puncture needle being configured to penetrate the cover and puncture the plug,wherein the puncture needle is provided on a connector main body,the cover is held by a slider,the slider is movable with respect to the connector main body in a longitudinal direction of the puncture needle, andthe slider is provided with a claw capable of engaging with a flange at the mouth of the container.2. The drug container connector according to claim 1 ,wherein the drug container connector is configured such that a tip of the cover abuts against the plug in a state in which the claw is engaged with the flange of the container.3. The drug container connector according to claim 1 , further comprising:a lock mechanism for preventing disengagement between the claw and the flange.4. The drug container connector according to claim 3 ,wherein the lock mechanism includes: a grip arm on which the claw is formed and that can elastically bend and deform outwardly; and the connector main body for restricting bending and deformation of the grip arm.5. The drug container ...

Child Proof Closure

A child proof closure including an outer cap having a set of spaced apart apertures extending through a top surface of the outer cap, an inner cap dimensioned and configured to be assembled within the outer cap having a set of spaced apart receivers corresponding to the at least one set of spaced apart apertures of the outer cap, and a key having a set of spaced apart projections dimensioned and configured to be inserted through the spaced apart apertures of the outer cap to engage the spaced apart receivers of the inner cap when the spaced apart apertures of the outer cap are vertically aligned with the spaced apart receivers of the inner cap for unscrewing the assembled closure from the container by turning the key. 1. A closure comprising:an outer cap including at least one drive element disposed proximate a top interior surface of the outer cap and at least one aperture extending through an exterior surface of the outer cap proximate the top surface; a closure engaging mechanism disposed on an interior surface of the inner cap, the closure engaging mechanism dimensioned and configured to engage a corresponding container engaging mechanism for securing the inner cap to a container, and', 'at least one drive element disposed proximate a top exterior surface of the inner cap operable to engage the at least one drive element of the outer cap when the outer cap is turned in a first direction to screw the assembled closure onto a container, the at least one drive element including a key receiver; and, 'an inner cap dimensioned and configured to be assembled within the outer cap, the inner cap includinga key having at least one projection extending from a handle portion, the at least one projection dimensioned and configured to be inserted through the at least one aperture of the outer cap to engage the key receiver of the at least one drive element of the inner cap when the at least one aperture of the outer cap is vertically aligned with the key receiver of the at ...

Container for a Liquid Medicament

The present disclosure relates to a container for a liquid medicament that includes a wall structure with at least one flexible portion and confining an inner volume filled with the liquid medicament and an elongated extraction tube having at least a first portion and a second portion that are separated from each other along the tube and which are located inside the inner volume. The extraction tube is radially collapsible when exposed to a compressive force above a predefined threshold, and the first portion, which is located at a distal end of the extraction tube, is less resistive against radial collapsing than the second portion.

SEPTUM HOLDERS FOR USE IN SYRINGE CONNECTORS

Presented herein are embodiments of septum holders for use in syringe connectors that are used to connect syringes to other elements of liquid transfer apparatuses. The septum holders comprise a septum holder body, at least one resilient elongated arm that terminates with a distal enlarged element attached to the sides of the body, and a septum. The septum holders of the invention are characterized in that they comprise at least one bore that is created in the septum or in an insert fixed in either the body of the septum holder or in the septum that functions as the seat of a needle valve and in that the septum is attached to the bottom of the body of the septum holder projecting downwards parallel to the at least one elongated arm. 1. A septum holder comprising: a body having a disk shaped annular upper body part and a lower body part , at least one resilient elongated arm terminating with a distal enlarged element attached to the side of the body , and a septum fitted into the lower body part so that it extends downward parallel to the at least one arm;wherein the septum is made of a single piece of cylindrically shaped resilient material, the upper part of the septum has a diameter larger than the middle part of the septum in order to form a flange that rests on an annular ledge created around the inside of the bottom section of the body when the middle part of septum slides through the open center at the bottom of the bottom section and the lowest part of the septum of the septum holder has a diameter that matches that of a septum in a fluid transfer component; and, the septum comprises at least one bore created part of the way through the height of the middle part of the septum, wherein the bore functions as the seat of a needle valve and the diameter of the bore is smaller than the outer diameter of the shaft of a needle that functions as a second component of the needle valve.2. The septum holder of claim 1 , wherein the septum is held to the body by pushing ...

CONTAINER FOR ASEPTIC CONTENT

The present invention relates to a container equipped with a closure system particularly adapted for aseptically filled fluid contents. The invention also relates to the use of said container in a method for detecting spoilage of its fluid content. 1. A container , the content of which is an aseptic fluid , equipped with a closure system comprising a removable flexible foil sealed to container opening and a removable cap adapted to the container over the flexible foil , the removable cap is adapted such as creating a headspace between at least part of the foil and the inner surface of the top of the cap and in that the foil can deflect under the effect of pressure increase in the container.2. A container according to claim 1 , wherein the cap is equipped with at least one member for evacuation of gas from the headspace.3. A container according to claim 2 , wherein the member for evacuation of gas from the headspace comprises at least one orifice.4. A container according to claim 1 , wherein the height of the headspace is such that the flexible foil can fully deflect under the effect of pressure increase in the container.5. A container according to claim 1 , wherein the flexible foil is made of a layered material comprising at least one aluminium layer.6. A container according to claim 1 , wherein the cap is adapted such as creating a headspace between substantially the whole surface of the flexible foil that is not sealed to the container opening and the inner surface of the top of the cap.7. A container according to claim 1 , wherein the aseptic fluid is a food product or a beverage.8. A container according to claim 7 , wherein the food product is a nutritional composition or a health care product.9. A container according to claim 8 , wherein the food product is an infant formula.10. A container according to claim 1 , wherein the pressure inside the container is lower than the pressure outside of the container when the fluid is aseptic.11. A container according to ...

Drainage system with retention ring

In one general aspect, the present disclosure provides a drainage system. The drainage system may include a container having an interior and a mouth, the mouth having an outer surface and an opening. A frangible seal may cover the opening. A cap may be secured to the mouth, and the cap may be in fluid communication with a drainage line. The cap may have an inner surface for engaging with the outer surface of the mouth. The drainage system may further include a retention ring with a collar having an inner surface configured to engage an outer surface of the cap, where the retention ring includes a bead for at least partially concentrating a restriction force provided by the retention ring on an adjacent area of the outer surface of the cap.

DRAINAGE SYSTEM WITH RETENTION RING

In one general aspect, the present disclosure provides a drainage system. The drainage system may include a container having an interior and a mouth, the mouth having an outer surface and an opening. A frangible seal may cover the opening. A cap may be secured to the mouth, and the cap may be in fluid communication with a drainage line. The cap may have an inner surface for engaging with the outer surface of the mouth. The drainage system may further include a retention ring with a collar having an inner surface configured to engage an outer surface of the cap, where the retention ring includes a bead for at least partially concentrating a restriction force provided by the retention ring on an adjacent area of the outer surface of the cap. 1. A drainage system , the drainage system comprising:a container having an interior and a mouth, the mouth having an outer surface and an opening;a frangible seal covering the opening;a cap secured to the mouth and in fluid communication with a drainage line, the cap having an inner surface for engaging the outer surface of the mouth; anda retention ring with a collar having an inner surface configured to engage an outer surface of the cap,wherein the retention ring includes a bead for at least partially concentrating a restriction force provided by the retention ring on an adjacent area of the outer surface of the cap.2. The drainage system of claim 1 , wherein the outer surface of the mouth includes a protrusion claim 1 , and wherein the bead of the retention ring is located distally of the protrusion of the mouth.3. The drainage system of claim 1 , wherein the retention ring includes a tab extending from the collar claim 1 , the tab having a surface for receiving a removal force.4. The drainage system of claim 3 , wherein the collar of the retention ring includes a collar portion having a relatively low bending moment of inertia with respect to adjacent areas of the collar such that the collar portion deforms in response to ...

ARRANGEMENT AND METHOD FOR PROVIDING A FORMULATION FOR PARENTERAL NUTRITION

The invention relates to an arrangement and a method for preparing a formulation for parenteral nutrition. In more detail the invention relates to a mixing system for parenteral nutrition, comprising at least two containers, wherein the at least two containers form a modular system. The mixing system comprises a septum, which is pierceable by a spike or a needle and a hanger for attaching the mixing system to an infusion rack. A first container comprises a male connector and a second container comprises a female connector, which fit together. First and second container can be coupled together, thereby forming a channel, which enables the passage of liquid and the mixing of the ingredients of the containers. 120-. (canceled)21. A mixing system for parenteral nutrition , said mixing system comprising at least two containers that form a modular system , said at least two containers comprising a first container filled with a first liquid for parenteral nutrition and a second container filled with a second liquid for parenteral nutrition , wherein said mixing system further comprises a septum and a hanger , wherein said septum is pierceable by a spike or a needle , wherein said hanger is configured for attaching said mixing system to an infusion rack , wherein said first container comprises a male connector and said second container comprises a female connector that fits said male connector , wherein said first and second containers are configured to be coupled together by connecting said male and female connectors so as to form a channel that enables passage of liquid , said channel permitting mixing of said first and second liquids.22. The mixing system of claim 21 , wherein said at least two containers comprises a third container claim 21 , wherein said first container contains amino acids claim 21 , said second container contains glucose claim 21 , and said third container contains fat.23. The mixing system of claim 21 , wherein said first container further comprises ...

Protective Cap

A protective cap () for application on a medical device such as a medical vial () comprising a membrane holder () in which a resilient membrane () is mounted. The protective cap () is provided with connection means () for connecting the cap () to the medical device (). The resilient membrane () comprises a piercing portion () and a sealing portion () and is mechanically and/or adhesively held in the protective cap () and is arranged to be brought into seailng contact with a receiving portion of the medical device () when the protective cap () is applied on the medical device (). 1. A protective cap for application on a medical device such as a medical vial , said protective cap comprising:a membrane holder having a first end with an end wall, said end wall having an outer surface and an inner surface and a second end with an end opening at a distance from said first end, said second end being adapted to be placed over a receiving portion of said medical device and being provided with a connection arrangement for connecting said protective cap to said medical device, said end wall of said membrane holder having a piercing opening said piercing opening having a peripheral edge,wherein a resilient membrane is arranged to cover said piercing opening, said resilient membrane comprising a piercing portion and a sealing portion, said membrane holder comprising an attachment arrangement for attaching said resilient membrane to said membrane holder said attachment arrangement being an adhesive attachment means or a mechanical attachment or a combination of an adhesive attachment and a mechanical attachment means, said resilient membrane being attached in said membrane holder with said piercing portion of said resilient membrane exposed through said piercing opening in said end wall of said membrane holder and with said sealing portion of said resilient membrane arranged to be brought into sealing contact with said receiving portion of said medical device when said protective ...

CARTRIDGE PORTION OF TRANSDERMAL DRUG DELIVERY APPARATUS AND METHODS

A cartridge, which may be suitable for use as a portion of a transdermal drug delivery apparatus, may include a body at least partially defining an interior for containing fluid for being delivered by the transdermal drug delivery apparatus. The body may also at least partially define first and second openings to the interior of the body, wherein the first and second openings are respectively proximate opposite first and second ends of the body. The cartridge may also include a self-sealing member at least partially closing the first opening, and a movable member at least partially closing the second opening, wherein at least a portion of the movable member is for being urged into the interior of the body for increasing pressure within the interior of the body. 1. A cartridge for supplying fluid in a transdermal drug delivery apparatus , the cartridge comprising:a body at least partially defining an interior for containing fluid for being delivered by the transdermal 'first and second openings to the interior of the body, wherein the first', 'drug delivery apparatus, and'}and second openings are respectively proximate opposite first and second ends of the body;a self-sealing member at least partially closing the first opening; anda movable member at least partially closing the second opening, wherein at least a portion of the movable member is for being urged into the interior of the body for increasing pressure within the interior of the body.2. The cartridge according to claim 1 , wherein the self-sealing member comprises a self-sealing septum.3. The cartridge according to claim 1 , wherein:the movable member comprises a deformable membrane, andat least a portion of the deformable membrane is for being urged into the interior of the body for increasing pressure within the interior of the body.4. The cartridge according to claim 3 , wherein the deformable membrane is a flexible membrane.5. The cartridge according to claim 1 , wherein:the self-sealing member is part ...

MOTION-ACTIVATED SEPTUM PUNCTURING DRUG DELIVERY DEVICE

A method and apparatus are disclosed for delivery of a drug to a recipient. In some embodiments, the delivery apparatus may unseal a drug containing reservoir. In some embodiments, the delivery rate may be controlled and/or adjustable. Optionally the apparatus may be disposable. Optionally, the apparatus may have a low profile and/or be wearable and/or attachable to the recipient. Optionally, discharge of the drug and/or unsealing of the reservoir may be driven by a plunger moving parallel to the base of the apparatus. Optionally, the apparatus may release a hypodermic needle into the recipient. Optionally, release of the hypodermic needle may be in a direction non-parallel and/or orthogonal to the direction of movement of the plunger. Optionally, prior to release, the hypodermic needle may be preserved in an aseptic state by a needle opening septum sealing a needle opening. Optionally, upon release, the hypodermic needle may pierce the needle opening septum. 1. A method for delivering a drug to a recipient with a delivery apparatus , the drug contained in a reservoir initially sealed by a seal for long term aseptic storage , the delivery apparatus including a hollow needle and a plunger , the method comprising:a) attaching a surface of the delivery apparatus to the recipient;b) applying a force with the plunger to a contents of the reservoir;c) puncturing the seal with the hollow needle by said force;d) discharging the drug from the reservoir by said force subsequent to said puncturing;e) detecting a rate of said discharging, andf) adjusting said rate of said discharging based on a result of said detecting.2. The method of claim 1 , wherein said applying said force is in a direction substantially parallel to said surface.3. The method of claim 1 , further comprising:g) supplying a torque, andh) converting said torque into said force.4. The method of claim 3 , wherein said detecting is by measuring a rotation driven by said torque.5. The method of claim 1 , wherein ...

CAP SYSTEMS WITH PIERCING MEMBER FOR PHARMACEUTICAL VIALS

A cap system for sealing injectable drugs within a vial is disclosed. The system includes an elastomeric stopper, a retainer member, a locking member, a cap assembly and a piercing member. The retainer member is arranged to snap onto the vial and the locking member slid with respect to the retainer member to permanently seal the vial. The cap assembly includes a cap and a band and is coupled to the locking member. The cap releasably holds the piercing member. The band is arranged to be removed to enable the cap to move the piercing member to penetrate the stopper, whereupon the cap can be removed. The piercing member is arranged to be connected to a syringe or other instrument to withdraw the vial's contents. 1. A cap system for a pharmaceutical vial having an interior in which a flowable material is disposed , an opening to the interior of the vial and a flanged neck surrounding the opening , the flanged neck having an undersurface , said cap system comprising:an elastomeric stopper arranged to be secured to the vial;a retainer member comprising a sidewall and a plural resilient fingers located about the periphery of said sidewall, said retainer member being arranged to be secured to the vial with said fingers of said retainer member being arranged to flex over the flanged neck of the vial and then snap into engagement with the undersurface of the flanged neck of the vial;a locking member slidably coupled to said retainer member and comprising a peripheral sidewall including inwardly projecting members, said locking member being arranged slid to a fixed position with respect to said retainer member, whereupon said inwardly projecting members of said locking member apply an inward force on said fingers of said retainer member to permanently seal said vial;a cap member coupled to said locking member, said cap member being hollow and having a socket therein; anda piercing member, said piercing member being releasably located in said socket and having a piercing tip.2. ...

Liquid-Transfer Adapter Beveled Spike

A liquid-transfer adapter operatively interposable between an injector and a vial is provided. The liquid-transfer has an injector engaging portion configured for fluidly coupling to an injector and a vial coupling. The vial coupling includes a spike that has a spike axis and a tip portion configured for piercing a septum of a vial. The tip portion includes a plurality of facets that meet each other at one or more edges and at least one of the one or more edges is sloped with respect to the spike axis. The spike defines a channel extending therethrough in fluid communication with the injector engaging portion. A channel opening is defined in at least one of the facets and disposed without interrupting the edges. 1. A liquid-transfer adapter operatively interposable between an injector and a vial , comprising:an injector engaging portion configured for fluidly coupling to an injector; anda vial coupling including a spike that has a spike axis and a tip portion configured for piercing a septum of a vial, the tip portion including plurality of facets that meet each other at one or more edges, at least one of the one or more edges being sloped with respect to the spike axis, the spike defining a channel extending therethrough in fluid communication with the injector engaging portion and including a channel opening defined in at least one of the facets and disposed without interrupting the edges.2. The liquid-transfer adapter of claim 1 , wherein the edges comprise junctions between the facets.3. The liquid-transfer adapter of claim 1 , wherein the edges comprise cutting surfaces configured for cutting the septum as the spike is pushed therethrough.4. The liquid-transfer adapter of claim 1 , wherein the tip portion comprises at least three facets.5. The liquid-transfer adapter of claim 4 , wherein the channel opening comprises a channel opening disposed in each of at least three of the facets.6. The liquid-transfer adapter of further comprising a seal disposed at the ...

EVACUATED BOTTLE SYSTEM

An evacuated bottle system including a bottle defining a hollow interior, the bottle having a neck with a rim defining an opening; a cap assembly supported on the bottle, the cap assembly including a funnel having a first portion and a second portion, the first portion being insertable within the interior of the bottle and the second portion engaging a portion of the bottle to support the funnel above the rim, the funnel defining a bore that fluidly communicates with the hollow interior of the bottle; a self-sealing membrane that covers the bore formed by the funnel to selectively seal the hollow interior of the bottle; a cap attachable to the bottle, the cap including a cover portion that extends at least partially over the self-sealing membrane to restrain movement thereof, the cover portion being axially spaced from the self-sealing membrane to define a gap that permits axial movement of the self-sealing membrane to selectively open the bottle to fluid communication outside of the bottle. 1. A cap assembly , the cap assembly comprising:a funnel having a first portion and a second portion;the first portion including a first wall defining a first bore and the second portion including a floor extending radially outward from the first portion to form a shoulder adjacent to the first portion;a second wall extending upward from the floor defining a second bore, the first bore and second bore being in fluid communication with each other;a self-sealing membrane having a first portion and a second portion, wherein the first portion is received in the first bore and wherein the second portion is received in the second bore of the funnel and includes a perimeter that extends radially outward of the first portion to overlap at least a portion of the floor; anda cap that is configured to fit over the second portion of the funnel, the cap defining at least one evacuating opening configured to receive a suction, the cap including a cover portion that extends radially inward ...

Gripping Attachment for a Bottle

A gripping attachment () is disclosed which facilitates the handling of a medication bottle (). The medication bottle includes a container () having a cylindrical wall () extending parallel to a longitudinal axis. The container is closed at one end by a base wall () and has an opposed open end. The container receives a cap () on the open end to enclose the container. The gripping attachment comprises a sleeve portion () having a sleeve wall () defining an internal, cylindrical surface configured to removably attach to the container wall. The gripping attachment further comprises a leverage component connected to the sleeve portion to facilitate gripping the sleeve portion. 1. A gripping attachment device to facilitate handling a medication bottle , the medication bottle including a container having a cylindrical wall extending parallel to a longitudinal axis , the container being closed at one end by a base wall and having an opposed open end , the container receiving a cap on the open end to enclose the container , said attachment comprising:a sleeve portion having a sleeve wall defining an internal, cylindrical surface configured to removably attach to the container wall to inhibit relative movement therebetween; anda leverage component connected to said sleeve portion to facilitate gripping said sleeve portion.2. The device of in which said leverage component comprises the sleeve wall having a tacky outer surface.3. The device of in which the sleeve wall comprises a cylindrical outer surface claim 1 , said leverage component comprising surface features projecting from the cylindrical outer surface away from the sleeve wall.4. The device of in which the surface features comprise vertical ribs.5. The device of in which the surface features comprise horizontal ribs.6. The device of in which the surface features comprise a textured surface7. The device of in which the sleeve wall comprises a cylindrical outer surface and said leverage component comprises a knob ...

MEDICINAL VIAL STOPPER

A medicinal vial stopper has a stopper plug extending from a stopper flange. The stopper plug is insertable with a compression fit in the neck of the vial. A first bore within the stopper plug has a radially inwardly facing first-bore surface having a constant first-bore diameter the entire first-bore length and a first-bore first end closed by a centrally-located piercable portion of the stopper flange. A second bore within the stopper plug has a radially inwardly facing second-bore surface having a constant second-bore diameter the entire second-bore length. The second-bore diameter is greater the first-bore diameter. The second-bore first end is in fluid communication with the first-bore second end. The centrally-located piercable portion of the stopper flange is resiliently deformable and upon being pierced by a spike tightly conforms to the radially outwardly facing sidewall of the shaft; thereby forming a fluid impenetrable seal. 1100. A vial stopper for sealing an open end of a neck of a vial containing a medicament withdrawable from the vial by a spike able to pierce the stopper , a neck flange circumscribing the open end and having a generally annular shape , the spike comprising a shaft having a radially outwardly facing sidewall with a diameter D , a lumen within the shaft having at least one vent proximal to a tip of the shaft and through which the medicament may be drawn into the lumen , the vial stopper comprising:{'sub': F', 'L', 'L, 'b': '1', 'a stopper flange having a circular disk-like shape with a stopper-flange outer diameter Dbisected by a stopper flange longitudinal axis “X” and a flange thickness “T” in a direction parallel to the longitudinal axis X, the stopper flange having a first side , a second side spaced the flange thickness from the first side and a centrally-located stopper-flange portion piercable by the spike;'}{'sub': P', 'L', 'F, 'a stopper plug extending from the second side of the stopper flange, the stopper plug having a ...

ENTERAL NUTRITION CONTAINER CAP AND METHODS OF MAKING AND USING THE CAP

A package closure system may include a package outlet including a first connection element and a cap configured to removably connect to the package outlet using the first connection element and comprising a second connection element. An overcap can be configured to removably connect to the cap using the second connection element. A method for providing a nutritional composition from a container to an enteral line may include: removing an overcap from a cap, the cap is configured to direct a nutritional composition through a channel within the cap, the cap removably connected to the container; connecting the cap sealingly to the enteral line; and applying a pressure to the container to direct the nutritional composition from the container through the channel and into the enteral line.

MODULAR DOSING ASSEMBLY OF MEDICAL SUBSTANCES

Systems, devices and method to establish fluid communication between vessels. A vessel having at least two entry ports and at least one exit port, and at least one container containing a dosing regimen, the at least one container configured to be received by one of the at least two entry ports of the vessel, whereby upon connection of the at least one container to the one of the at least two entry ports of the vessel, the dosing regimen in the at least one container is transferred into the vessel. Modular dosing system for adding at least one amount of a medicament to a preparation in a modular construction. System for displaying a dosing regimen or single amount of a medicament, so that the administrator of the amount is able to precisely ascertain the amount administered to a patient. 1. A system for intermixing beneficial substances , comprising:a bag having at least two entry ports and an exit port;at least two containers containing an amount of a medicament;wherein the at least two entry ports are configured to be received and engaged by the at least two entry ports of the bag,wherein upon connection of the at least two containers to the at least two entry ports of the bag, the amount of the medicament in the at least two containers is transferred into the bag.2. The system of claim 1 , wherein when the at least two containers are engaged to the at least two entry ports of the bag claim 1 , the at least two containers abut the bag.3. The system of claim 1 , wherein when the at least two containers are engaged to the at least two entry ports of the bag claim 1 , the at least two containers abut a wall of the bag.4. The system of claim 1 , wherein when the at least two containers are engaged to the at least two entry ports of the bag claim 1 , the at least two containers are surface mounted to the bag.5. The system of claim 1 , wherein when the at least two containers are engaged to the at least two entry ports of the bag claim 1 , the at least two containers are ...

MODULAR DOSING ASSEMBLY OF MEDICAL SUBSTANCES

Systems, devices and method to establish fluid communication between vessels. A vessel having at least two entry ports and at least one exit port, and at least one container containing a dosing regimen, the at least one container configured to be received by one of the at least two entry ports of the vessel, whereby upon connection of the at least one container to the one of the at least two entry ports of the vessel, the dosing regimen in the at least one container is transferred into the vessel. Modular dosing system for adding at least one amount of a medicament to a preparation in a modular construction. System for displaying a dosing regimen or single amount of a medicament, so that the administrator of the amount is able to precisely ascertain the amount administered to a patient. 1. A modular dosing system for intermixing a beneficial substance , comprising:at least three containers, at least one of the at least three containers including an amount of a medicament;wherein at least three of the containers are configured to be connected and form a fluidic communication between each other,wherein upon connection of the at least three containers, the amount of medicament in at least one of the containers is in fluid communication with the other containers.2. The system of claim 1 , wherein at least one of the at least two containers have a decontamination interface which operates as a dual entry and exit port.3. The system of claim 1 , wherein at least one of the at least two containers has a decontamination interface which operates as the exit port into a device selected from the following group of an infusion line claim 1 , a filter claim 1 , or a needle.4. The system of claim 1 , wherein the force of gravity pulls the amount of medicament into an infusion line that operates as the exit port.5. The system of claim 1 , wherein at least one of the at least two containers are attached to the other container having at least one of the entry ports in a vertical or ...

Syringe Adaptor and Complementary Fluid-Port Adaptor

A syringe adaptor includes a body, shaped to define a body lumen, a syringe fitting at a proximal end of the body, configured to connect to a distal end of a syringe, a needle extending distally from the syringe fitting into the body lumen, a septum housing, and an elastomeric septum mounted inside the septum housing. The septum includes a proximal face, shaped to define an aperture having an aperture diameter, and a distal face. The septum is shaped to define a cavity, joined to the aperture, having a cavity diameter that is larger than the aperture diameter. The septum housing is configured to slide proximally within the body lumen such that a distal end of the needle contained in the cavity passes through the distal face of the septum. Other embodiments are also described.

DRUG CONTAINER CLOSURE FOR MOUNTING ON OPEN-TOPPED DRUG CONTAINER TO FORM DRUG RECONSTITUTION ASSEMBLAGE FOR USE WITH NEEDLELESS SYRINGE

A drug container closure for mounting on an open-topped drug container to form a ready-to-use drug reconstitution assemblage for use with a needleless syringe. The drug container closure includes a drug container stopper for sealing the drug container and a fluid transfer member with an integral needleless syringe connector and a puncturing cannula. The fluid transfer member is manually disposed along a diametric inverted L-shaped track pair from an initial non-puncturing position to a puncturing position. The inverted L-shaped track pair includes one-way snap members to prevent a user returning the fluid transfer member to an earlier position and indicating progress of the user activation. 1. A drug container closure for mounting on an open-topped drug container to form a ready-to-use drug reconstitution assemblage for use with a needleless syringe , the open-topped drug container having a drug container rim defining a drug container opening , the drug container closure having a longitudinal centerline and comprising: i) an one-way retaining snap member between said open-ended upright access leg and said horizontal priming leg,', 'ii) an one-way primed snap member between said horizontal priming leg and said proximal activation leg end, and', 'iii) an one-way activated snap member towards said distal activation leg end;, '(a) a tubular closure housing for securely mounting on the drug container rim, said closure housing including at least one inverted L-shaped track having an open-ended upright access leg, a horizontal priming leg and an upright activation leg, said activation leg having a proximal activation leg end and a distal activation leg end correspondingly adjacent and distal to said priming leg, each said inverted L-shaped track having(b) a drug container stopper securely mounted on said closure housing for sealing the drug container opening on securely mounting said closure housing on the drug container rim; and 'said fluid transfer member being initially ...

DISINFECTING MULTI-DOSAGE VIAL CAP

A disinfecting cap and method of manufacturing may include a first section and a second section. The first section may include a first plate, a container, a first seal, a second seal, and a sanitizing agent. The second section may include a sleeve mount. The container may include a second plate, a lateral wall, and an inner chamber, the inner chamber and the lateral wall being positioned between the first plate and the second plate, with the second section being adjacent to the second plate and opposite the first plate and the first needle port and the second needle port being collinearly aligned to the sleeve mount. 1. A disinfecting cap comprises:a first section;a second section;the first section comprises first plate, a container, a first seal, a second seal, and a sanitizing agent;the second section comprises a sleeve mount;the container comprises a second plate, a lateral wall, and an inner chamber;the first plate and the second plate comprise a first needle port and a second needle port, respectively;the lateral wall being peripherally positioned around the inner chamber;the inner chamber and the lateral wall being positioned between the first plate and the second plate;the second section being adjacent to the second plate and opposite the first plate;the first needle port and the second needle port being collinearly aligned to the sleeve mount;the first seal being occusively positioned against the first needle port within the container;the second seal being occusively positioned against the second needle port within the sleeve mount; andthe sanitizing agent being retained within the inner chamber between the first seal and the second seal.2. The disinfecting cap of comprises:the second section comprises a plurality of ribs, radially positioned within the sleeve mount adjacent to the second plate.3. The disinfecting cap of comprises:the second section comprises a shaft opening and at least one wedge-hook fastener;the shaft opening being positioned opposite the ...

CONNECTOR SYSTEM COMPRISING AT LEAST TWO WITHDRAWAL PORTS

A connector system for connecting a withdrawal device to a container for a medical fluid, in particular for a rinsing solution, comprising a first withdrawal port and a second withdrawal port which are each designed for a withdrawal of the medical fluid from the container, wherein the first withdrawal port and the second withdrawal port are designed differently and each is sealed by a resealable membrane and a break-away cap. 115-. (canceled)16. A connector system for attaching a withdrawal device to a container for a medical liquid , said connector system comprising a first withdrawal port and a second withdrawal port , which are each designed for withdrawing the medical liquid from the container , the first withdrawal port and the second withdrawal port being of different designs and each being closed by a reclosable membrane and a break-off cap.17. The connector system as claimed in claim 16 , wherein the first withdrawal port and the second withdrawal port are designed to receive a withdrawal device with in each case different flow rates and/or different attachments.18. The connector system as claimed in claim 16 , wherein the first withdrawal port is designed to receive a first withdrawal device with a cylinder attachment claim 16 , and/or in that the second withdrawal port is designed to receive a second withdrawal device with a spike attachment.19. The connector system as claimed in claim 16 , wherein the first withdrawal port has an outer thread and can be connected to the first withdrawal device by means of the cylinder attachment of the first withdrawal device being screwed on claim 16 , and a fluid connection can be produced by opening the membrane claim 16 , and/or in that the second withdrawal port can be connected to the second withdrawal device by means of the spike attachment of the second withdrawal device being pushed into the membrane of the second withdrawal port claim 16 , and a fluid connection can be produced by opening the membrane.20. The ...

Rfid tag and blood container/system with integrated rfid tag

The present disclosure relates to arrangements for attaching an RFID tag to a liquid container, and particularly to a blood components container. The RFID tag may be inserted in an enclosure, such as peel tab, or in a sealed cup attached to a container port. The tag could alternately be embedded in a molded plug or component attached to a port. The RFID antenna could be painted or stamped on the surface of the container. Or the tag could be inserted into the container to float freely in the liquid components. The RFID source may be secured around the neck of a rigid or semi-rigid container, attached with a tether or attached to a connector assembled in association with a blood component or other fluid flow path.

MULTI-CELL SEALED CONTAINER

Described in one aspect is a multi-cell or multi-chambered container for sealing various materials such as therapeutic or diagnostic agents, animal or human tissue, tissue samples, specimens, blood, genetic material, or any other material. The container includes seals formed by folding the wall of the elongate body transverse to the interior of the elongate body and maintaining the folded wall portions adjacent one another or joining them together. In another aspect, the container disclosed may be made according to a method involving creating multiple seals at various locations along the elongate body thus creating sealed voids or cells between the seals within the elongate body. 1. A container , comprising:an elongate body with a first, second, and third seal at three separate locations respectively along the elongate body defining a first hermetically sealed void within the elongate body between the first and second seals, and a second hermetically sealed void within the elongate body between the second and third seals;wherein at least one of the first or second hermetically sealed voids contains a therapeutic or diagnostic agent;wherein the elongate body has a wall defining an interior lumen that has an inner surface;wherein the first seal includes a plurality of folds in the wall defining corresponding sealing portions of the wall;wherein the sealing portions extend transverse to the interior lumen; andwherein the sealing portions are joined to one another to form the first seal.2. The container of claim 1 , wherein the first seal claim 1 , the second seal claim 1 , and/or the third seal each includes at least three folds defining at least three sealing portions per seal claim 1 , the sealing portions extending transverse to the interior lumen in different directions claim 1 , and wherein the sealing portions are on the inner surface of the interior lumen.3. (canceled)4. The container of claim 1 , wherein the sealing portions are fused together to form a unitary ...

SEALING CAP FOR A CONTAINER FOR HOLDING A MEDICAL LIQUID

A sealing cap for a container for holding a medical liquid comprising a cap body, which bounds an interior and has at least one opening, and at least one connection device, which is arranged on the cap body and to which a conveying device for feeding a medical liquid into the container or for removing a medical liquid from the container can be connected. The connection device has a sealing element, arranged on the cap body. The connection device has a break-off piece, which, in an initial state, is firmly connected to the cap body and covers the outer face of the sealing element in the outward direction. The break-off piece is connected to the cap body by means of a pre-determined breaking point. In addition, the sealing element is convex on the outer face. 115-. (canceled)17. The sealing cap as claimed in claim 16 , wherein an interior between the break-off part and the outside surface of the sealing element is provided in a sterile manner.18. The sealing cap as claimed in claim 16 , wherein the sealing element protrudes outward by way of its outside surface in relation to a top surface of the cap body.19. The sealing cap as claimed in claim 16 , wherein a sealing head of the sealing element extends right through the opening and realizes the outside surface.20. The sealing cap as claimed in claim 16 , wherein a center of the convex outside surface of the sealing element is between 0.1 and 1 mm claim 16 , preferably between 0.3 mm and 0.7 mm claim 16 , above an outer upper edge of a sealing head of the sealing element.21. The sealing cap as claimed in claim 16 , wherein the predetermined breaking point extends around the opening.22. The sealing cap as claimed in claim 16 , wherein the sealing cap comprises a first connecting device for removing a medical liquid and a second connecting device for supplying a medical liquid.23. The sealing cap as claimed in claim 22 , wherein each connecting device comprises a sealing element claim 22 , wherein the sealing elements ...

Spinning Female Luer with Threadably Removable Feature

An adapter for connection with a fluid container includes an outer housing having a distal end, a proximal end, and a substantially cylindrical sidewall extending between the distal end and the proximal end, an inner member including a body rotatably inserted within the outer housing, a connector extending from the body configured to connect the adapter to a fluid container, and at least one grasping member extending from the inner member, the grasping member being configured for grasping by a user of the adapter, a first locking arrangement engageable with a distal end of the inner member and configured to restrict the inner member from rotating relative to the outer housing in a first direction, and a second locking arrangement engageable with a proximal end of the inner member and configured to restrict the inner member from moving in a proximal direction relative to the outer housing. 1. An adapter for connection with a fluid container , the adapter comprising:an outer housing having a distal end, a proximal end, and a sidewall extending between the distal end and the proximal end;an inner member comprising a rotatable body inserted within the outer housing, a connector extending from the body configured to connect the adapter to a fluid container, and at least one grasping member extending from the inner member;a first locking arrangement engageable with the inner member and configured to restrict the inner member from rotating relative to the outer housing in a first direction; anda second locking arrangement engageable with the inner member and configured to restrict the inner member from moving in a proximal direction relative to the outer housing,wherein the adapter is transitionable between a disengaged state, in which both the first locking arrangement and the second locking arrangement are not engaged with the inner member, a first fully engaged state in which the first locking arrangement engages the inner member, and a second fully engaged state in ...

HERMETIC CLOSING PLUG FOR A SEALED STERILE VIAL CONTAINING MEDICAL OR NUTRITIONAL ACTIVE SUBSTANCES, SUITABLE FOR THE STERILE CONNECTION TO A CONTAINER OF LIQUID DILUENT SOLUTION, AND STERILE CONNECTION SYSTEM USING SAID CLOSING PLUG

A closing plug for a sealed sterile vial containing medical or nutritional active substances, which is suitable for the sterile connection to a container of liquid diluent solution. There is also described a sterile connection system between a sealed sterile vial closed by means of a plug and a tube for drawing said active substances, for mixing them with a liquid diluent solution inside a sterile container. The plug requires an internal sterile chamber in which, upon the piercing of an outer film for sealing the plug, a compressible protection cap of a piercing tip of the tube is inserted, which abuts against a seat of the sterile chamber allowing the tip to pierce the end wall of the protection cap and then the inner membrane of the closing plug. An intermediate pierceable membrane placed on the seat of the internal chamber of the vial may be included. 2. The sterile connection system according to claim 1 , wherein said closing plug of the vial comprises a further internal or intermediate pierceable membrane placed on said seat of the internal chamber of the plug.3. The sterile connection system according to claim 1 , wherein said closing plug is in thermoplastic material.4. The sterile connection system according to claim 3 , wherein said internal pierceable membrane is in one piece with the plug.5. The sterile connection system according to claim 1 , wherein said outer sealing film or membrane of the closing plug is in medical paper claim 1 , thermoplastic material claim 1 , rubber claim 1 , silicone claim 1 , thin aluminum or other suitable easily pierceable material claim 1 , eventually in one piece with the closing plug.6. The sterile connection system according to claim 1 , wherein said protection cap of the piercing to of the drawing and mixing tube is in rubber o silicone or other suitable material with pierceable end wall claim 1 ,7. The sterile connection system according to claim 2 , wherein said further internal or intermediate pierceable membrane is ...

PUMPLESS THROMBECTOMY SYSTEM

A thrombectomy catheter system can include a catheter configured for insertion into vasculature of a patient. The system includes a pressure chamber configured to isolate an internal volume from a surrounding environment. The system can include an infusion container including an infusion fluid therein. The pressure chamber can receive the infusion container. A drive unit can pressurize a working fluid in the pressure chamber with the infusion container received in the pressure chamber. In an example, pressurizing of the working fluid correspondingly compresses the infusion container to pressurize the infusion fluid and transfer the infusion fluid to the catheter. In an example, the infusion fluid is isolated from the working fluid by the infusion container when the working fluid is pressurized in the pressure chamber. 1. A thrombectomy catheter system , comprising:a catheter configured for insertion into vasculature of a patient;a pressure chamber configured to isolate an internal volume from a surrounding environment;an infusion container including an infusion fluid, wherein the infusion container is configured for reception in the pressure chamber;a drive unit configured to pressurize a working fluid in the pressure chamber with the infusion container received in the pressure chamber, wherein the pressurizing of the working fluid correspondingly compresses the infusion container to pressurize the infusion fluid and transfer the infusion fluid to the catheter; andwherein the infusion fluid is isolated from the working fluid by the infusion container when the working fluid is pressurized in the pressure chamber.2. The thrombectomy catheter system of claim 1 , further comprising a working fluid contained configured to supply the working fluid.3. The thrombectomy catheter system of claim 1 , further comprising a spike configured to pierce the infusion container claim 1 , wherein the infusion spike facilitates fluidic communication between the infusion container and ...

CARTRIDGE PORTION OF TRANSDERMAL DRUG DELIVERY APPARATUS AND METHODS

A cartridge, which may be suitable for use as a portion of a transdermal drug delivery apparatus, may include a body at least partially defining an interior for containing fluid for being delivered by the transdermal drug delivery apparatus. The body may also at least partially define first and second openings to the interior of the body, wherein the first and second openings are respectively proximate opposite first and second ends of the body. The cartridge may also include a self-sealing member at least partially closing the first opening, and a movable member at least partially closing the second opening, wherein at least a portion of the movable member is for being urged into the interior of the body for increasing pressure within the interior of the body. 1. A method of at least partially assembling a transdermal drug delivery apparatus , the method comprising: the microneedle assembly is mounted to the receptacle, and', 'the cartridge contains fluid for being supplied to the microneedle assembly; and, 'moving a cartridge into a receptacle and toward a microneedle assembly, wherein'} the engagement of the connector comprises the connector transitioning from an unconnected state to a connected state,', 'in the connected state, the connector is configured to temporarily restrict movement of the cartridge toward the microneedle assembly so that the cartridge is spaced apart from and out of fluid communication with the microneedle assembly,', 'the connector includes a first connector part and a second connector part,', 'the receptacle includes the first connector part, and', 'the cartridge includes the second connector part., 'the movement of the cartridge toward the microneedle assembly being arrested in response to engagement of at least one connector, wherein'}2. The method according to claim 1 , wherein:the connector comprises a snap-fit connector; andthe first and second connector parts comprise snap-fit connector parts.3. The method according to claim 1 , ...

Method and Apparatus for Producing Primary Packaging Having an Integrated Septum and Primary Packaging Having an Integrated Septum

The invention relates to a method for producing primary packaging having an integrated septum characterised by: a) providing a septum, b) providing an injection-molding die having two die halves, c) positioning the septum in the injection-molding die, d) moving the two die halves of the injection-molding die to form a cavity corresponding to the shape of the primary packaging to be produced, e) injecting a material into the cavity via an injection opening, where the two die halves of the injection-molding die pretensioningly holding the septum, and a rim of the septum is overmolded by the material, f) cooling the injected material while maintaining a holding pressure, g) moving the two die halves of the injection-molding die such that the produced primary packaging means having the integrated septum can be removed from the injection-molding die, and h) removing the produced primary packaging having the integrated septum from the injection-molding die. 1. A method for producing primary packaging having an integrated septum comprising the steps of:a) providing a septum,b) providing an injection-molding die having two die halves able to be moved relative to one another,c) positioning the septum in the injection-molding die,d) moving the two die halves of the injection-molding die such that a cavity is formed that corresponds to the shape of the primary packaging to be produced,e) injecting a material into the cavity in the injection-molding die via an injection opening in one of the die halves of the injection-molding die, the two die halves of the injection-molding die pretensioningly holding the septum therebetween, and a rim of the septum being overmolded by the material, a region of the septum in contact with the two die halves remaining free of material,f) cooling the injected material while maintaining a holding pressure, as a result of which the primary packaging is formed having an integrated septum,g) moving the two die halves of the injection-molding die such ...

VIAL CLOSURE FOR REHYDRATING MEDICATION

A vial cap is configured to releasably contain a portion of a material, for example a powdered medication, for dispensing into a container. Via operation of a depressable plunger, the material is released into the container for rehydrating and mixing with a liquid, and thereafter may be extracted, such as via a needle. In this manner, a rehydrated medication may be provided in a predetermined amount and at a desired time. 1. A cap for a container holding a liquid , the cap comprising:a cap body comprising a durable material, the cap body configured with a space for containing an anhydrous material;a depressable plunger coupled to the cap body, the depressable plunger having an extended portion to release the anhydrous material into the liquid when the depressable plunger is depressed;a flexible o-ring operable as a seal for the depressable plunger; anda septum disposed at least partially within the depressable plunger, the septum operable to permit a needle to pass therethrough to access the liquid.2. The cap of claim 1 , wherein the o-ring and the septum are monolithic.3. The cap of claim 1 , wherein the depressable plunger is protected from accidental activation by being at least partially contained within the cap body.4. The cap of claim 1 , further comprising a releasable agitator disposed in the space for containing the anhydrous material.5. The cap of claim 1 , wherein the anhydrous material is a medication that must be administered intravenously.6. The cap of claim 1 , wherein the depressable plunger comprises a heel that forces a portion of a membrane into an opened position claim 1 , and wherein the membrane at least partially surrounds the anhydrous material.7. The cap of claim 1 , wherein the depressable plunger locks into a depressed position after being depressed.8. A method for rehydrating a powdered medication in preparation for intravenous injection claim 1 , the method comprising:coupling a vial cap containing the powdered medication to a vial ...

PILL DISPENSER AND DISTRIBUTOR

A device and method of dispensing and distributing materials, such as pills, capsules, and medication, are disclosed. A container of pills or other material may be placed in contact with or in proximity to the device, which may have a curved or contoured bottom surface. Material may be dispensed from the container into the device. An optional barrier may block movement and unintentional distribution or dispensing of the material. Material may be received in a retention area. The barrier may be moved so as to allow for passage of the material. Material may be dispensed from the dispenser and may be distributed onto other surfaces or into other volumes, such as daily, weekly, or monthly pill holders. The barrier may optionally be used to assist in moving the material and in dispensing or distributing the pills or other material. 1. A device for dispensing material , comprising:a length extending from a first end of the device to a second end of the device;a first wall;a second wall;a material receiving area comprising a material receiving surface;a dispensing tip;a container receiving surface; anda bottom surface;wherein the bottom surface comprises at least one curved surface which defines a longitudinal axis which extends substantially along the length, the first wall extends substantially parallel to the longitudinal axis, the second wall extends substantially parallel to the longitudinal axis, and wherein the first wall, the second wall, and the receiving surface define a first receiving volume in the receiving area, and further wherein the first receiving volume is at least partially open, and wherein the dispensing tip further comprises a dispensing end located proximate to the first end and substantially on an opposing side of the material receiving surface from the container receiving surface along the longitudinal axis.2. The device according to claim 1 , further wherein the first wall and the second wall extend substantially away from the bottom surface ...

SYSTEMS AND METHODS FOR SAFE MEDICAMENT TRANSPORT

A medicament transport system includes a syringe adapter assembly; and a vial adapter assembly including a base defining an opening having a seal member disposed therewithin, a stem extending from the base and defining a lumen therethrough and an opening through a wall thereof, a needle shuttle valve slidably disposed within the lumen of the stem and supporting a transfer needle and a vacuum needle; and a vacuum cup slidably supported on the stem, wherein a vacuum chamber is defined in the space between the base, the stem and the vacuum cup. The medicament transport system includes a condition where the transfer needle and the vacuum needles penetrate the seal member of the vial adapter assembly, and the vacuum cup is moved to draw a vacuum through the vacuum needle. An automation system is provided that utilizes a medicament transport system for forming a medicament solution from a liquid/non-liquid solution. 1. (canceled)2. A process of operating an automation system for effectuating transport of a medicament , the process comprising: at least one vial containing a quantity of a medicament, the vial being capped by a stopper;', 'at least one vial adapter assembly having a transfer needle, a first seal and a second seal;', 'at least one syringe including a barrel and a plunger slidably supported within the barrel, the barrel containing a dilutent therein; and', 'at least one syringe adapter assembly including a seal;, 'providing an automation system loaded with connecting the at least one vial adapter assembly to the at least one vial such that the second seal of the at least one vial adapter assembly is adjacent the stopper of the at least one vial;', 'connecting the at least one syringe adapter assembly to the at least one syringe;', 'moving the at least one syringe and the at least one syringe adapter assembly into connection with the assembled at least one vial and the at least one vial adapter assembly, wherein the seal of the at least one syringe adapter ...

STORAGE OR INFUSION BOTTLE

The present invention relates to a storage or infusion bottle () with a bottle neck () moulded integrally thereon, the bottle neck having at least one teat-shaped bottle feature () projecting from its mouth end, the closed teat end wall () of said bottle feature being designed to be puncturable by an infusion needle. The storage or infusion bottle () according to the invention is characterized in that a cap () is attachable to the bottle neck (), in that the cap () has at least one funnel-shaped cap feature (), its () feature interior space accommodating at least the free end region of the corresponding bottle feature (), and in that the intermediate space between the end wall of the at least one bottle feature () and the opposing side of the corresponding cap feature () is completely filled by a hat-shaped sealing element () which encloses the bottle feature () at least in its end region facing away from the storage or infusion bottle () and which is held at the circumference of its hat shape in a form-fitting and/or force-fitting manner on the circumference of the bottle feature (). 11345678389109104545910111245145. Storage or infusion bottle () with a bottle neck () moulded integrally thereon , the bottle neck having at least one teat-shaped bottle feature ( , ) projecting from its mouth end , the closed teat end wall ( , ) of said bottle feature being designed to be puncturable by an infusion needle , characterized in that a cap () is attachable to the bottle neck () , in that the cap () has at least one funnel-shaped cap feature ( , ) , its ( , ) feature interior space accommodating at least the free end region of the corresponding bottle feature ( , ) , and in that the intermediate space between the end wall of the at least one bottle feature ( , ) and the opposing side of the corresponding cap feature ( , ) is completely filled by a hat-shaped sealing element ( , ) which encloses the bottle feature ( , ) at least in its end region facing away from the storage ...

Cover for Drug Product Bottles

The cover is made with two parts that close on each other over a cap on a drug product bottle. Each cover part has a semi-cylindrical periphery, a semi-circular lid and a radially inwardly directed ledge along a bottom edge of the semi-cylindrical periphery to fit under the cap of a bottle in a closed position. The cover parts snap together to lock in place. In one embodiment, the cover cooperates with a handle assembly having a handle of U-shape that is disposed over the cover to prevent separation of the two parts from each other. 1. A cover for mounting over a screw cap on a neck of a drug product bottle , said cover comprisinga pair of parts hingedly secured together to move between an open position and a closed position in facing relation to each other to form a cup shape in said closed position;each said part having a semi-cylindrical periphery, a semi-circular lid and a radially inwardly directed ledge along a bottom edge of said semi-cylindrical periphery to fit under the cap of the bottle in said closed position; anda lip projecting from said periphery and said lid of one of said pair of parts for slidable reception within the other part of said pair of parts in said closed position to seal said pair of parts together in face-to-face manner.2. A cover as set forth in further comprising a locking means for securing said pair of parts together in said closed position.3. A cover as set forth in wherein said locking means includes a radially directed integral abutment with a slot of rectangular shape on said periphery of one of said pair of parts and an integral tab with a barb on the other part of said pair of parts sized to slide through said slot and to engage behind said abutment in said closed position.4. A cover as set forth in wherein said abutment is disposed adjacent an edge of said one part facing the other part.5. A cover as set forth in wherein each part of said pair of parts is made of plastic.6. A cover as set forth in further comprising an ...

Needle Protection Device

A device () for bringing a first vessel member () in fluid communication with a needle member (), which device () includes an adaptor () having a housing () with a holding arrangement () configured to secure the needle () to the housing (), where the housing () has at least a first opening () sealed by a seal (); a cutting device () configured to perforate the seal (). The cutting device () is configured to perforate the seal () and thereby break the seal () by bringing the seal () into contact with the cutting device () by moving the adaptor () towards the vessel member () in a manner in which the needle member () is not brought into contact with the seal (). 1. A device for bringing a first vessel member in fluid communication with a needle member , the device comprising:a needle member;an adaptor having a housing comprising a holding arrangement configured to secure the needle member to the housing, the housing having at least a seal and a first opening sealed by the seal; andcutting means configured to perforate the seal;wherein the cutting means is configured to perforate the seal and break the seal by bringing the seal into contact with the cutting means by moving the adaptor towards the vessel member in a manner in which the needle member is not brought into contact with the seal.2. A device according to claim 1 , wherein the needle member comprises a hollow needle or a hollow spike having at least one through-bore having a first opening and a second opening.3. A device according to claim 1 , wherein the at least a seal comprises a first seal and a second seal claim 1 , and the adaptor comprises a second opening sealed by the second seal.4. A device according to claim 1 , wherein:the adaptor comprises a sterile needle member; andthe adaptor is sealed in a manner so that the seal keeps the needle member sterile during storage.5. A device according to claim 1 , further comprising:a collar provided with protruding cutting edges and less protruding pressing edges ...

Attachment Device For Medical Fluid Container

An attachment device for connecting a fluid path set to a medical container includes a body having a pointed distal end configured for puncturing a membrane of the medical container and a proximal end configured for connecting to the fluid path set. The attachment device further includes a fluid channel extending along a longitudinal axis of the body between the distal end and the proximal end. The fluid channel is configured for delivering a medical fluid between the medical container and the fluid path set. At least one deflectable retaining element projects from the body of the attachment device between the distal end and the proximal end. The at least one retaining element is configured from non-removably retaining the attachment device with the medical container after the attachment device is connected to the medical container. 1. An attachment device for connecting a fluid path set to a medical container , the attachment device comprising:a body having a pointed distal end and a proximal end configured for connecting to the fluid path set;one or more removable elements configured to removably connect to the pointed distal end of the body, the one or more removable elements having a distal end configured for extending through a membrane of the medical container;at least one fluid channel extending along a longitudinal axis of the body and the one or more removable elements, the at least one fluid channel configured for delivering a medical fluid between the medical container and the fluid path set; andat least one retaining element associated with each of the body and one or more removable elements and projecting from the body and each of the one or more removable elements,wherein the at least one retaining element on a most distal removable element is configured for non-removably retaining the most distal removable element of the attachment device within the medical container after the attachment device is connected to the medical container, while allowing ...

RESERVOIR MODULE FOR PUMP DISPENSER

The current invention discloses a fluid reservoir module for holding a fluid that may be used in a fluid dispenser. The fluid reservoir has a base, a reservoir body enclosing an internal void, and at least one removable tab attached to the reservoir body. The reservoir body is disposed on the base and the removable tab blocks inserting the reservoir body into a dispenser body. By detaching the removable tab(s), the reservoir body may be inserted into the dispenser body. Simultaneously, a fluid transfer structure, preferably a hollow spike, may penetrate a frangible part of the reservoir so that fluid in the reservoir may be extracted. The fluid in the reservoir is preferably pre-loaded. The current invention is particularly useful for dispensing small amounts of fluid, such as eye drops, but it may also be scaled up for larger volumes. 2. The fluid reservoir module of claim 1 , further comprising a removable tab attached to the reservoir body claim 1 , wherein the removable tab blocks inserting the reservoir body into the dispenser body claim 1 , and removal of the removable tab allows the insertion of the reservoir body into the dispenser body.3. The fluid reservoir module of claim 1 , further comprising a removable tab attached to the reservoir body claim 1 , wherein the removable tab blocks inserting the reservoir body into the dispenser body claim 1 , and removal of the removable tab allows the insertion of the reservoir body into the dispenser body claim 1 , and further comprising a base claim 1 , wherein the reservoir body is disposed on the base and the bottom portion is connected to the base.4. The fluid reservoir module of claims 1 , further comprising ribs attached to the base claims 1 , wherein the ribs are connected to the bottom portion of the reservoir body.5. The fluid reservoir module of claim 1 , further comprising ribs attached to the base claim 1 , wherein the ribs are connected to the bottom portion of the reservoir body claim 1 , and wherein the ...

SEPTUM THAT DECONTAMINATES BY INTERACTION WITH PENETRATING ELEMENT

A septum is penetrable by a needle for decontamination by physical interaction. The septum can include a peripheral portion, an exterior surface], and an interior surface. A penetration portion extends between the exterior and interior surfaces, is spaced inwardly of the peripheral portion, and is penetrable by the needle or other penetrating element. A flex portion is located between the penetration portion and the peripheral portion. A thicker portion extends between the flex portion and the penetration portion, and defines an increased thickness between the exterior and interior surfaces relative to the flex portion. The flex portion is flexible inwardly relative to the peripheral portion during penetration of the penetration portion by a needle or other penetrating element. The penetration portion physically interacts with and decontaminates the needle when it penetrates the septum. The septum may also reduce or prevent retrograde contamination when the needle is withdrawn. 1. A septum comprising:a peripheral portion extending about a periphery of the septum, an exterior surface located on an external side of the septum, and an interior surface located on an opposite side of the septum;a penetration portion penetrable by a needle or other penetrating element extending between the exterior and interior surfaces that is spaced inwardly of the peripheral portion and is penetrable by the needle or other penetrating element;a flex portion located between the penetration portion and the peripheral portion; andan increased thickness portion extending between the flex portion and the penetration portion, and defining an increased thickness between the exterior and interior surfaces relative to the flex portion, wherein the flex portion is flexible inwardly relative to the peripheral portion during penetration of the penetration portion by a needle or other penetrating element, and the penetration portion physically interacts with and decontaminates the needle or other ...

PRESSURE-REGULATING VIAL ADAPTORS

A vial adaptor can include a connector interface and/or a piercing member. The vial adaptor can include a regulator assembly. The regulator assembly can include a regulator base, a regulator nest coupled with the regulator base, and/or a storage chamber formed at least partially by one or both of the regulator base and regulator nest. The regulator assembly can include a cover connected to one or both of the regulator base and regulator nest and fitted around a radially outward portion of one or both of the regulator base and regulator nest. In some cases, the regular assembly includes a flexible enclosure connected to the regulator nest and configured to transition between a contracted configuration and an expanded configuration. In some cases, the flexible enclosure is inhibited from transitioning to the expanded configuration prior to removal or modification of the cover from the regulator assembly. 1. (canceled)2. A pressure-regulating vial adaptor comprising:a body portion;a regulator channel extending between a piercing member and a proximal regulator aperture; and regulator base comprising an annular wall;', 'a filter chamber comprising a filter, the filter being configured to filter ambient air passing through the filter chamber;', 'a regulator nest being configured to couple with the regulator base;', 'a flexible enclosure being at least partially positioned within the regulator nest, the flexible enclosure being configured to transition between a stored configuration and an expanded configuration; and', 'a cover being coupled to the regulator base such that the cover at least partially extends along the flexible enclosure, the annular wall, the regulator nest, and the filter chamber, the cover comprising an aperture, the cover being further configured to permit the flexible enclosure to at least partially extend through the aperture as the flexible enclosure transitions from the stored configuration towards the expanded configuration., 'a regulator ...

DEVICES AND SYSTEMS WITH AN EXTERNAL DISPLACEMENT MECHANISM FOR CONTAMINANT-FREE ENGAGEMENT OF PHARMACEUTICAL VESSELS AND PHARMACEUTICAL ADMINISTRATION DEVICES

The present invention relates, in some embodiments thereof, to systems, devices and methods allowing for an engagement of two or more vessels or devices in a decontaminated manner. In some embodiments of the invention, the systems and devices of the invention include a first connection interface attached to a first vessel and a second connection interface attached to a second vessel, wherein the first connection interface and the second connection interface are configured to allow for an engagement between the first vessel and the second vessel, and wherein the first and second connection interfaces are further configured to externally displace from the engagement between the first vessel and the second vessel while a hermetically sealed connection is maintained between the first vessel and the second vessel. 1. A decontamination system for the engagement of vessels , the system comprising:a first connection interface attached to a first vessel; anda second connection interface attached to a second vessel,wherein said first connection interface and said second connection interface are configured to allow for an engagement between said first vessel and said second vessel, andwherein said first connection interface and the second connection interface are further configured to externally displace from said engagement between said first vessel and said second vessel while a hermetically sealed connection is maintained between said first vessel and said second vessel.2. The system of claim 1 , wherein at least one of said first connection interface and said second connection interface is a film claim 1 , a plastic claim 1 , or a metal alloy.3. The system of claim 1 , wherein claim 1 , upon the engagement between said first vessel and said second vessel claim 1 , said first connection interface and said second connection interface are configured to slide with respect to said first vessel and said second vessel claim 1 , thereby removing contaminants between said first ...

DEVICES AND SYSTEMS WITH AN EXTERNAL DISPLACEMENT MECHANISM FOR CONTAMINANT-FREE ENGAGEMENT OF PHARMACEUTICAL VESSELS AND PHARMACEUTICAL ADMINISTRATION DEVICES

The present invention relates, in some embodiments thereof, to systems, devices and methods allowing for an engagement of two or more vessels or devices in a decontaminated manner. In some embodiments of the invention, the systems and devices of the invention include a first connection interface attached to a first vessel and a second connection interface attached to a second vessel, wherein the first connection interface and the second connection interface are configured to allow for an engagement between the first vessel and the second vessel, and wherein the first and second connection interfaces are further configured to externally displace from the engagement between the first vessel and the second vessel while a hermetically sealed connection is maintained between the first vessel and the second vessel. 1. A container housing a substance intended for intracorporal administration to a patient , the container comprising:a rail mechanism, andan externally displaceable connection interface,wherein the rail mechanism is configured to provide for the external displacement of the connection interface.2. The container of claim 1 , wherein the container further comprises an engagement mechanism.3. The container of claim 2 , wherein the engagement mechanism is selected from a group consisting of a thread claim 2 , a ratchet teeth mechanism claim 2 , an adhesive claim 2 , a snap-on mechanism and combinations thereof.4. The container of claim 1 , wherein the connection interface is disposed on the rail mechanism.5. The container of claim 1 , wherein the connection interface is disposed between rails of the rail mechanism.6. The container of claim 1 , wherein the connection interface is attached to the rail mechanism via a frangible seal claim 1 , wherein the frangible seal is configured to break/rupture by a force of a user's hand upon displacement of the connection interface from the rail.7. The container of claim 1 , wherein the container has a flexible wall.8. The ...

Systems and methods for safe medicament transport

A medicament transport system includes a syringe adapter assembly; and a vial adapter assembly including a base defining an opening having a seal member disposed therewithin, a stem extending from the base and defining a lumen therethrough and an opening through a wall thereof, a needle shuttle valve slidably disposed within the lumen of the stem and supporting a transfer needle and a vacuum needle; and a vacuum cup slidably supported on the stem, wherein a vacuum chamber is defined in the space between the base, the stem and the vacuum cup. The medicament transport system includes a condition where the transfer needle and the vacuum needles penetrate the seal member of the vial adapter assembly, and the vacuum cup is moved to draw a vacuum through the vacuum needle. An automation system is provided that utilizes a medicament transport system for forming a medicament solution from a liquid/non-liquid solution.

ACCESS DEVICE FOR CONTAINERS OF FLUIDIZABLE SUBSTANCES

An access device for containers of fluidizable substances includes a body provided with a hollow spike designed to be inserted into a container of a substance to fluidize and having an axial fluid passage and an axial passage for venting of the container, an expandable chamber connected to the venting passage of the spike through a lateral passage of the body, a first check valve enabling one-way communication from the lateral passage to the expandable chamber, a second check valve enabling one-way communication from a vent opening to the venting passage of the spike. A double impermeable filtering membrane is interposed between the first check valve and the second check valve. 1. Access device for containers of fluidizable substances comprising:a body provided with a hollow spike designed to be inserted into a container of a substance to fluidize and having an axial fluid passage and an axial passage for venting of the container,an expandable chamber connected to said venting passage of the spike through a lateral passage of the body,a first check valve enabling one-way communication from said lateral passage to said expandable chamber,a second check valve enabling one-way communication from a vent opening to the venting passage of the spike, and whereinimpermeable filtering membrane means which prevents the inlet of liquids into said expandable chamber, and the loss of liquids from said vent opening, said impermeable filtering membrane means are interposed between said first check valve and said second check valve.2. Access device according to claim 1 , wherein said impermeable filtering membrane means comprises two impermeable filtering membranes parallel and adjacent to each other so as to delimit an intermediate chamber in communication with said venting passage of the spike.3. Access device according to claim 1 , wherein said expandable chamber comprises a half-shell housing and a flexible membrane fixed to said housing claim 1 , wherein said flexible membrane ...

METHOD FOR INCREASING THE LEAKAGE RESISTANCE IN A CLOSED, PRESSURIZED SYSTEM COMPRISING A SEPTUM-SEALED CONTAINER

The present invention relates to a method for increasing leakage resistance in a closed, pressurized system. The method involves providing a closed system including a container sealed with a septum having a top surface with an exposed section, which is maintained under a positive pressure of at least about 5 psig. A contact surface of a hard component is fixedly placed adjacent to or in contact with at least a portion of a border section or a central section of the exposed section of the septum, or both, to reduce the size of any bulge or deformation formed in the exposed section of the septum. The present invention also relates to a kit for increasing leakage resistance in a closed, pressurized system, which includes the hard component. 115-. (canceled)16. An apparatus for infusing a receptacle by increasing leakage resistance in a closed , pressurized system , comprising:a closed system comprising a container sealed with a septum in contact with the container, the septum having a first surface with a first exposed section and a second surface with a second exposed section generally opposite the first exposed surface, wherein the second exposed section of the septum is exposed to an interior of the container, the system capable of being maintained under a positive pressure of at least about 34.5 kPa (5 psig), anda contact surface of a hard component fixedly placed in contact with the first exposed section of the septum,wherein the placement of the contact surface is configured to contact any outward bulge or deformation formed in the septum caused by positive pressure,and wherein the contact surface is further capable of withstanding positive pressure to prevent leakage resistance from the closed system.17. The apparatus according to claim 16 , wherein the positive pressure maintained in the closed system is in the range of from about 34.5 kPa (5 psig) to about 2 claim 16 ,413 kPa (350 psig).18. The apparatus according to claim 16 , further comprising at least one ...

Apparatus and method for buffering solutions

The present invention is directed to a method an apparatus for buffering an anesthetic solution prior to an injection. The inventive apparatus employs a modified carpule which hold two solutions in fluid isolation. The buffering solution is separated from the anesthetic solution within the same carpule by way of a fluid impervious thin film. The thin film has a weakened central area which can be easily pierced by a harpoon affixed to one side of a plunger. As the plunger is advanced forward, the harpoon breaks through the thin film and causes mixing of the two solutions. 1. A modified carpule apparatus for a syringe used to mix two solutions comprising;a generally cylindrical main body having an axially slidable plug contained therein, said main body having first and second fluid filled hollow portions separated by a seal with a piercable center;a projection extending from said plug, wherein axial movement of said plug can cause piercing of said center releasing fluid from said first hollow portion into said second hollow portion.2. The apparatus of wherein said seal has a rigid outer portion.3. The apparatus of wherein said outer portion is formed of a plastic material.4. The apparatus of wherein said first and second hollow portions have inner walls and said plug has an outer diameter in sealing relation with said inner walls.5. The apparatus of wherein said piercing of said seal causes fluid to flow from said first fluid filled hollow portion to said second fluid filled hollow portion.6. The apparatus of wherein said first hollow portion contains a first medication and said second hollow portion contains a second medication.7. The apparatus of wherein said first medication is a buffering solution and said second medication is an anesthetic. The present invention relates generally to methods and apparatus for buffering anesthetics.More particularly, the present invention relates to methods for preparing and storing sodium bicarbonate buffering solutions and ...

DISPOSABLE VIAL HOLDER AND METHOD TO PREVENT NEEDLE STICK INJURIES

A vial holder is provided to protect a user's hand from needle sticks. The holder includes a handle and a shield attached to a distal end of the handle. An opening is formed in the distal end of the handle to receive a vial. The vial is placed through the opening and into a passageway of the handle with the upper end of the vial exposed. A user grasps the handle which holds the vial in a stabilized manner. A needle may then safely approach the vial in which inadvertent slippage or movement of the needle results in contact with the needle against the shield and not contact with the user's hand. 1. A vial holder comprising:a handle having an opening formed at distal end thereof, and a passageway communicating with said opening, said passageway extending a depth within a portion of the handle from said distal end toward a proximal end of said handle;a shield attached to a distal end of the handle;a flange connected to and protruding from said opening, and said flange extending radially inward into said passageway;said passageway is tapered commencing at a larger diameter at said opening to a smaller diameter towards said proximal end of said handle; andwherein said vial holder is made as a single member.2. A vial holder claim 1 , as claimed in claim 1 , wherein:said shield is made from a needle impenetrable plastic having a first stiffness, and said handle is made from a plastic having a second lesser stiffness.3. A vial holder claim 1 , as claimed in claim 1 , wherein:said shield is substantially circular shaped.4. A vial holder claim 1 , as claimed in claim 1 , wherein:said shield is substantially planar.5. A vial holder comprising:a handle having an opening formed at distal end thereof, and a passageway communicating with said opening, said passageway extending a depth within a portion of the handle from said distal end toward a proximal end of said handle;a shield attached to a distal end of the handle;a flange connected to said shield and extending from said ...

RUBBER FOR BABY BOTTLE NIPPLES, PACIFIERS, & SYRINGE PLUNGERS

The production of a protein free synthetic polyisoprene which has both low levels of chemical impurities and good physical properties has yet to be realized. It has now been envisioned that the use of neodymium catalyzed polyisoprene will offer the combined advantages of both a clean, as well as, high cis-1,4 polymer. Synthesis of polyisoprene rubber using a neodymium based catalyst system is described. Characterization of the material shows the absence of an ultra high molecular weight fraction and the presence of very high cis-1,4-microstructure. Gum stock and black filled compound studies comparing neodymium polyisoprene with natural rubber, titanium polyisoprene, and lithium polyisoprene have been performed. Results indicate that polyisoprene rubber synthesized using a neodymium catalyst system (Nd—PI) has similar stress-strain and tear properties as synthetic titanium polyisoprene. Analysis of residual volatile, extractable, and oligomer levels indicates Nd—PI is indeed a clean source of high cis synthetic polyisoprene. 1. A breast hood to be connected to a milk pump , said breast hood comprising a wall means forming an outer surface and an inner surface , said inner surface being substantially conical so as to have a wide opening end for engaging a female breast , and a small opening end , said outer surface being of a first , relative rigid material , while said inner surface is comprised of polyisoprene rubber made with a neodymium catalyst , wherein the polyisoprene rubber is made by a process which comprises polymerizing isoprene monomer in the presence of a neodymium catalyst system and terminating the polymerization with an alkaline aqueous neutralizer solution , wherein the neodymium catalyst system is prepared by (1) reacting a neodymium carboxylate with an organoaluminum compound in the presence of isoprene for a period of about 1 minutes to about 12 hours to produce neodymium-aluminum catalyst component , and (2) subsequently reacting the neodymium- ...

Feeding Cap, Drive Head, And Drive System

The present invention is comprised in the sector of the industry dedicated to the manufacturing of medical supplies, particularly focusing on containers for the artificial feeding of enteral feeding products through a tube. In particular, the present invention relates to a closure cap for a container for supplying enteral feeding products by means of the drive of a drive head, and it also relates to a drive head that can be coupled to the cap for driving the supply of enteral feeding products contained in a container, and in turn to a drive system formed by said cap and drive head.

Method and apparatus for precise measurement and dispensing of liquids

A dispenser device for dispensing fluids is described. The dispenser can include a reservoir cap that can directly attach to and replace the screw top cap of traditional screw top bottle. The reservoir cap includes an air reservoir that can facilitate movement of the fluid through the device. The reservoir cap is coupled to a dispenser that is configured to receive the fluid from the cap. The dispenser can be detached from the cap and used to directly dispense the fluid.

DRUG SECURITY SYSTEMS AND METHODS

The present disclosure provides an injectable medication security device. The device may comprise a recess on a first portion of the device. The recess may be configured to receive and couple to a neck portion of a vial containing the injectable medication. The device may comprise an opening on a second portion of the device, to permit access to a penetrable cover of the vial. The device may comprise at least one aperture configured to control access to the opening. The device may comprise a depressible switch. The depressible switch may be configured to cause the at least one aperture to open and provide access to the opening when the depressible switch is depressed, thereby permitting the medication to be drawn from the vial. The depressible switch may be configured to cause the at least one aperture to lock and close the opening when the depressible switch is released. 1. An injectable medication security device , comprising:a recess provided on a first portion of the device, wherein the recess is configured to receive and couple to a neck portion of a vial containing the injectable medication;an opening provided on a second portion of the device, wherein the opening permits access to a penetrable cover located near the neck portion of the vial;at least one aperture located at the opening and configured to control access to the opening; anda depressible switch operatively coupled to the at least one aperture, wherein the depressible switch is configured to (1) cause the at least one aperture to open and provide access to the opening when the depressible switch is depressed, thereby permitting the medication to be drawn from the vial, and (2) cause the at least one aperture to lock and close the opening when the depressible switch is released, thereby preventing further access to any residual medication within the vial.2. The injectable medication security device of claim 1 , wherein the at least one aperture comprises a scannable visual code that is revealed when ...