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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 5151. Отображено 100.
17-05-2012 дата публикации

Transdermal patch with on-board energy storage device

Номер: US20120123335A1
Автор: Frederick A. Sexton
Принадлежит: Purdue Pharma LP

A transdermal patch can include a drug source, a porator, and an energy storage device on-board the patch. Conductive contact terminals can extend from the energy storage device for connection to an external source of power. The porator operates free of any concurrent connection to any external source of power. A switch can be used to make the selective electrical connection between the porator and the energy storage device. The switch can be arranged to respond to a manual user action after the patch has been adhered to skin, including separation of the porator from a remainder of the patch. Optionally, a series of switches can make electrical connections between the porator and respective individual energy storage devices. In another aspect, a transdermal patch includes a mechanical bias that applies a displacement force to the porator to thereby better ensure good physical contact between the porator and the skin.

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Номер записи: 1
18-10-2012 дата публикации

Electrical Stimulation Treatment of Hypotension

Номер: US20120265280A1
Автор: BRUCE Simon, JP Errico, Steven Mendez
Принадлежит: ElectroCore Inc

The present invention includes methods and devices for treating hypotension, such as in cases of shock, including septic shock, anaphylactic shock and hypovolemia. The method includes the step of applying at least one electrical impulse to at least one selected region of a parasympathetic nervous system of the patient. The electrical impulse is sufficient to modulate one or more nerves of the parasympathetic nervous system to increase the ratio of blood pressure to heart rate and relieve the condition and/or extend the patient's life.

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Номер записи: 2
28-03-2013 дата публикации

ELECTRODE ARRANGEMENT

Номер: US20130079862A1
Автор: ELLRICH Jens
Принадлежит: CERBOMED GMBH

The invention relates to an electrode arrangement to be attached on and/or in the ear of a human, wherein the electrode arrangement is designed to exert a transcutaneous electric stimulation stimulus onto the surface of the ear and wherein the electrode arrangement has at least one stimulation electrode and at least one reference electrode. In order to achieve an improved transcutaneous stimulation, especially of the Vagus nerve, the invention provides that the at least one stimulation electrode contacts the surface of the ear via a first contact surface and that the at least one reference electrode contacts the surface of the ear via a second contact surface, wherein the second contact surface is at least three time the size of the first contact surface. 1. An electrode arrangement to be attached on and/or in the ear of a human , wherein the electrode arrangement is designed to exert a transcutaneous electric stimulation stimulus onto the surface of the ear , the electrode arrangement comprising:at least one stimulation electrode and at least one reference electrode,wherein the at least one stimulation electrode has an arcuated structure and contacts the surface of the ear via a first contact surface,wherein the at least one reference electrode has an oval or drused structure and contacts the surface of the ear via a second contact surface,wherein the second contact surface is at least three times the size of the first contact surface,wherein at least one of the electrodes contacts the surface of the ear via a contact surface, wherein the electrode is so designed that it covers at least 50% of the surface of the Cymba conchae of the ear.2. The electrode arrangement of claim 1 , wherein the second contact surface is at least five times the size of the first contact surface.3. The electrode arrangement of claim 1 , wherein the at least one stimulation electrode acts as a cathode and the at least one reference electrode as an anode in the electrical circuit which is ...

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Номер записи: 3
20-06-2013 дата публикации

Apparatus and method for relieving pain using transcutaneous electrical nerve stimulation

Номер: US20130158627A1
Автор: Andres Aguirre, Glenn Herb, Marc Cryan, Michael Williams, Shai N. Gozani, Xuan Kong
Принадлежит: NeuroMetrix Inc

Apparatus for transcutaneous electrical nerve stimulation in humans, comprising a housing; stimulation means mounted within the housing for electrically stimulating nerves; an electrode array releasably mounted to the housing, connectable to the stimulation means, and comprising electrodes for electrical stimulation of nerves; control means mounted to the housing and electrically connected to the stimulation means for controlling the stimulation means; monitoring means mounted to the housing and electrically connected to the stimulation means for monitoring the stimulation means; user interface means mounted to the housing and electrically connected to the control means for controlling the stimulation means; display means mounted to the housing and electrically connected to the control means and the monitoring means for displaying the status of the stimulations means; and a strap attached to the housing and configured to hold the housing, stimulation means and electrode array at a specific anatomical location to treat pain.

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Номер записи: 4
11-07-2013 дата публикации

Multilayer wound dressing with conductive regions

Номер: US20130178812A1
Автор: Niclas Flach
Принадлежит: Molnycke Health Care AB

Provided is a wound dressing including a wound pad of absorbent material having a first side and a second side opposite thereto, a backing layer covering the wound pad on the first side thereof an adhesive layer for attaching the dressing to skin. The backing layer has at least one conductive region and consists of plastic film.

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Номер записи: 5
18-07-2013 дата публикации

Voltage limited neurostimulation

Номер: US20130184779A1
Автор: Asif Rahman, Christoph Hahn, Justin Keith Rice, Marom Bikson, Preet Minhas, Shiraz A. Macuff
Принадлежит: Research Foundation Of City University of New York

Methods and systems for delivering voltage limited neurostimulation to a patient. In one aspect, a method includes initiating a flow of electrical current through a first electrode and a second electrode coupled to the patient and increasing the flow of electrical current toward a target value by increasing a voltage across the first electrode and second electrode. Prior to reaching the target value of electrical current, the method includes preventing the voltage across the first electrode and second electrode from increasing beyond a first predetermined limit; and subsequently, maintaining the voltage across the first electrode and second electrode at or within a predetermined range that does not exceed the first predetermined limit. The amplitude of the electrical current continues to increase toward the target value during at least part of a time when the voltage across the first electrode and the second electrode is maintained within the predetermined range.

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Номер записи: 6
25-07-2013 дата публикации

Composite electrode

Номер: US20130190847A1
Автор: Yoram Palti
Принадлежит: Novocure Ltd USA

An electrode for applying electric fields to a patient includes a plurality of ceramic elements (e.g., ceramic discs) that are designed to be positioned against the patient's skin. Electrical connections are made to the ceramic elements (e.g., using a flex circuit). Temperature sensors (e.g., thermistors) are preferably provided at at least some of the ceramic elements to sense the temperature at the skin beneath the ceramic elements, so that appropriate action can be taken if an overtemperature condition is detected.

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Номер записи: 7
01-08-2013 дата публикации

Systems and methods for percutaneous electrical stimulation

Номер: US20130197615A1
Автор: Jonathan L. Sakai, Joseph J. Mrva, Kenneth P. Rundle, Michael Marks, Robert B. Strother, Steven M. Galecki
Принадлежит: NDI Medical LLC

Systems and methods according to the present invention relate to a substantially extracorporeal pulse generator system for electrical stimulation of one or more target nerve or their branches using one or more preferably percutaneous leads each having one or more electrodes implanted in, on, around, or near the target nerve. Improved systems include a patch assembly configured to be adhesively mounted to a patient's skin and an electrical stimulation assembly configured to be mechanically mounted to the patch assembly. A preferred patch assembly, in addition to provide mechanical mounting of the stimulation assembly, provides a power source for the stimulation assembly, and may further serve as a return electrode. Associated system components and methods of use are also provided.

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Номер записи: 8
05-09-2013 дата публикации

ELECTRODE ARRANGEMENT

Номер: US20130231729A1
Автор: BAER Stefan, BECK Christoph, HARTLEP Andreas
Принадлежит: CERBOMED GMBH

The electrode arrangement applies a transcutaneous electrical stimulation stimulus to the surface of a section of the human ear. A holding element attaches at or in the ear. At least one electrode is held by an electrode carrier. The holding element has a linear guide on a supporting rod which is linear movable in the direction of a longitudinal axis of the holding element. The electrode carrier is arranged at the supporting rod. To improve the handling of the electrode arrangement latching means are between the linear guide and the supporting rod, so that the supporting rod can be latched relatively to the linear guide along the longitudinal axis in predetermined relative positions. The latching means is a rack shaped contour, which is on the supporting rod and which extends into the direction of the longitudinal axis of the holding element. 1. An electrode arrangement for applying of a transcutaneous electrical stimulation stimulus onto the surface of a section of the human ear , which comprises a holding element to be attached at or in the ear as well as at least one electrode , which electrode is arranged in or at an electrode carrier , wherein the holding element comprises a linear guide in which a supporting rod is arranged linear movable in the direction of a longitudinal axis (L) of the holding element and wherein the electrode carrier is arranged at the supporting rod ,whereinlatching means are effectively arranged between the linear guide and the supporting rod, so that the supporting rod can be arranged latched relatively to the linear guide along the longitudinal axis (L) in predetermined relative positions, wherein the latching means comprise a rack shaped contour, which is arranged at or on the supporting rod and which extends into the direction of the longitudinal axis (L) of the holding element.2. The electrode arrangement according to claim 1 , wherein the supporting rod and the rack shaped contour are designed as one piece.3. The electrode ...

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Номер записи: 9
12-09-2013 дата публикации

SYSTEMS AND METHODS FOR THERAPEUTIC ELECTRICAL STIMULATION

Номер: US20130238075A1
Автор: Bachinski Thomas Jerome, Lutz Dennis, Shindley Richard Paul
Принадлежит: EMPI INC.

In various embodiments, the invention disclosed herein provides systems, devices and methods for providing electrical stimulation to a patient. An electrical mechanical interconnection is provided to facilitate user friendly systems and devices. Exemplary therapeutic electrical stimulation devices include a shoe connected mechanically and electrically to a conductor that provides signals for electrical stimulation. 120-. (canceled)21. A system for delivering therapeutic electrical stimulation , comprising:a garment;at least one shoe attached to the garment, the at least one shoe being configured to couple to at least one controller;a plurality of electrodes connected to the garment, wherein the electrodes are positioned adjacent the garment; andat least one lead wire electrically connecting the plurality of electrodes to the at least one shoe.22. The system of claim 21 , wherein the garment comprises at least two layers and the shoe comprises a base claim 21 , and wherein the base is positioned between the at least two layers of the garment for physically holding the shoe within the garment.23. The system of claim 22 , wherein the at least one lead wire is positioned between the at least two layers of the garment.24. The system of claim 22 , wherein the shoe is exposed on an outer side of the garment to allow connection to the at least one controller.25. The system of claim 21 , wherein the garment comprises a belt configured to be worn around certain anatomy of a patient.26. The system of claim 21 , wherein the shoe is attached to the garment by at least one of: stitching claim 21 , gluing or embedding in a laminate layer.27. The system of claim 21 , wherein the plurality of electrodes are positioned on the garment in a grid pattern.28. The system of claim 21 , wherein the plurality of electrodes are connected to the garment by at least one of: sewing claim 21 , gluing claim 21 , or velcroing.29. The system of claim 21 , further comprising at least one electrically ...

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Номер записи: 10
17-10-2013 дата публикации

Electrodes Adapted for Transmitting or Measuring Voltages Through Hair

Номер: US20130274583A1
Автор: Heck Sandy L.
Принадлежит:

An electrode that functions alone, in clusters or arrays can be used to measure and/or deliver voltages through skin covered with hair by achieving reliable skin contact. In one form, a composite metal electrode has several raised points capable of passing through hair to contact the skin directly between hairs. Electrode points are distributed evenly over a flat circular or curved base to create a composite electrode or cluster in which all electrode points electrically couple to one another and to an output device. In another form of the invention, each electrode point is connected by a separate conductor wire to a selector that evaluates the signal during use and determines which of the electrode points are to be coupled to an output device. 1. A non-invasive skin surface electrode apparatus for placement adjacent to a mammalian body surface , said apparatus comprising ,a plurality of spaced apart projecting electrodes mounted upon a supporting base,each being located on said supporting base toward so as to be able to engage a skin surface while in use,each electrode has an electrically conductive surface positioned to be able to establish electrical contact with the skin during use,the electrodes being mounted upon said supporting base in at least one cluster or in an array that places the projecting conductive surface of the electrodes in a flat or curved coplanar arrangement such that at least one the electrodes of each cluster or array is adapted to transmit electric current to the body of a mammalian or to contact an area of the skin surface thereof where electrical impulses arising from nerve or muscle contractions can be received by the electrodes, andan electrical conductor wire connected to each electrode for conducting electric current to or from the body.2. The skin surface electrode apparatus of wherein the electrodes each have an elongated shaft and the electrode shafts are arranged in parallel relationship.3. The apparatus of wherein the electrodes ...

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Номер записи: 11
24-10-2013 дата публикации

Headband for External Occipital Neurostimulation

Номер: US20130282095A1
Автор: MIGNOLET Jean-Yves, Muller Pierre-Yves, Rigaux Pierre
Принадлежит: STX-Med Sprl

The present invention relates to a headband for use in neurostimulation made at least partly of elastic or stretch material comprising: 1. Headband for use in neurostimulation made at least partly of elastic or stretch material comprising:{'b': 2', '8, 'a hole () to be located directly on the rear part of the scalp () of a user, said hole being sized to fit the inion or occipital protuberantia;'}{'b': 1', '2', '7', '2, 'at least two electrodes () directly attached to the headband and positioned adjacent to and symmetric about said hole (), designed so that to be applied on the right and left branch of the occipital nerve () respectively, once the inion is put in correspondence with said hole () by the user;'}{'b': 6', '6', '6', '2, 'a connector (A) for connecting a wearable neurostimulator () to the headband, said connector (A) being located opposite to said hole (), once the headband is worn by the user and'}{'b': 6', '1, 'means coupled to the elastic or stretch material for electrically connecting said connector (A) and each of said electrodes ().'}21548. Headband according to claim 1 , characterised in that each electrode () comprises a flexible reservoir () for containing electrically conductive gel claim 1 , said reservoir being terminated with a metallic grid () intended to come directly in contact with the scalp () and to provide wet electrical contact without shaving.33. Headband according to claim 1 , characterised in that it comprises a linear piece of elastic or stretch material provided with snap fasteners () for closing or adjusting the headband to the head of the user.43619. Headband according to claim 3 , characterised in that at least part of the snap fasteners () are metallic and participate to the electric connection between said connector (A) and said electrodes ( claim 3 , ).533. Headband according to claim 4 , characterised in that the headband is made of a front part and a rear part and is adjustable to the user's head by means of a plurality ...

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Номер записи: 12
07-11-2013 дата публикации

External, head-worn electrical stimulator for treating headache conditions

Номер: US20130296967A1
Автор: Christopher Atkinson Durst, Ioannis Mihail Skaribas
Принадлежит: SKARIBAS IOANNIS MIHAIL MD

An external, head worn electrical nerve stimulation device, including a power source and a head band configured to fit around a patient's head, the patient's head including a front portion, a rear portion opposite the front portion, a first lateral side, and a second lateral side opposite the first lateral side. The device further includes a plurality of electrical electrodes circumferentially disposed along the head band, wherein the plurality of electrodes contacts each of the front portion, the rear portion, the first lateral side, and the second lateral side. The plurality of electrical electrodes is configured to stimulate, with electrical current, at least one of the greater occipital nerve, the lesser occipital nerve, the supraorbital nerve, the supratrochlear nerve, zygomatotemporal nerve, and the auriculotemporal nerve when the electrodes are energized by the power source.

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Номер записи: 13
14-11-2013 дата публикации

SYSTEMS AND METHODS FOR SELECTIVELY APPLYING ELECTRICAL ENERGY TO TISSUE

Номер: US20130304169A1
Автор: Simon Bruce J.
Принадлежит:

Systems and devices for selectively applying electrical energy to a target region beneath a skin surface of a patient involve applying an electrical impulse to one or more electrodes on a skin surface of the patient to modulate one or more nerves at the target region, where the impulse is substantially blocked at nerves located between the target region and the skin surface such that only the nerves at the target region are modulated by the electrical impulse. 1. A method of treating hypotension comprising:contacting an activating device to an outer skin surface of a patient; andapplying an electrical impulse to the activating device such that the electrical impulse modulates at least one nerve in a selected region of a carotid sheath of a patient in need of relief from hypotension, such that increased blood pressure is achieved.2. The method of claim 1 , wherein increased blood pressure is achieved by at least one of improving myocardium performance and controlling vasoconstriction.3. The method of claim 1 , further comprising substantially blocking the electrical impulse from modulating nerves in a second region between the outer skin surface and the selected region of the carotid sheath.4. The method of claim 1 , wherein the substantially blocking is carried out by deactivating one or more nerves located between the outer skin surface and the selected region of the carotid sheath.5. A method of treating bronchial constriction claim 1 , comprising:contacting an activating device to an outer skin surface of a patient; andapplying at least one electrical impulse to the activating device such that the electrical impulse stimulates a selected region of a carotid sheath of a patient in need of relief of bronchial smooth muscle constriction whereby the magnitude of constriction of the smooth muscle is reduced.6. The method of claim 5 , further comprising substantially blocking the electrical impulse from modulating nerves in a region between the outer skin surface and ...

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Номер записи: 14
14-11-2013 дата публикации

INTEGRATED BANDAGE AND ELECTRICAL STIMULATION TRANSCUTANEOUS ELECTRICAL NEURON-STIMULATION (TENS) DEVICE

Номер: US20130304176A1
Автор: Cantrell Barry, Riddle Kent
Принадлежит:

A bandage with an integrated, wireless, transcutaneous electrical neuron-stimulation (TENS) device, and method of using the same. The integrated bandage and TENS device provides electric stimulation to an anatomical site that is covered by the bandage. The bandage includes controls that enable the user to control the intensity levels of the electric stimulation, which is provided through at least one electrode. The electrical circuit in the TENS device provides biphasic or monophasic sequence of pulses to the electrodes, and the sequence of pulses form a plurality of waveforms available for specific clinical needs. 1. An apparatus comprising:a bandage; anda wireless transcutaneous electrical neuron-stimulation (TENS) device integrated with the bandage for providing electric stimulation to anatomical site that is covered by the bandage.2. The apparatus of wherein the apparatus comprises at least one integrated control for controlling the TENS device.3. The apparatus of wherein the at least one integrated control comprises at least one button for controlling operations selected from the group consisting of power on claim 2 , power off claim 2 , and electric stimulation intensity.4. The apparatus of wherein the at least one integrated control comprises a dial for controlling electric stimulation intensity.5. The apparatus of wherein an intensity level of the electric stimulation gradually changes in response to activation of the at least one integrated control.6. The apparatus of further comprising a visual indicator that visually indicates status information selected from the group consisting of power on claim 1 , power off claim 1 , and electric stimulation intensity.7. The apparatus of further comprising an integrated power supply the supplies power to the TENS device.8. The apparatus of wherein the integrated power supply is a battery.9. The apparatus of wherein integrated power supply is configured to not be replaceable or interchangeable within the apparatus.10. ...

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Номер записи: 15
28-11-2013 дата публикации

Brace, Device, and Method for Correcting Poor Posture

Номер: US20130317400A1
Автор: Ferezy Joseph Steven
Принадлежит:

A device for correcting poor posture comprises a wearable garment comprising a back brace, a plurality of electrodes connected to the wearable garment and configured to electrically stimulate human muscles, and an electric muscle stimulation unit connected to the plurality of electrodes and configured to provide electrical power to the plurality of electrodes. 1. A device for correcting poor posture , comprising:a wearable garment comprising a back brace;a plurality of electrodes connected to the wearable garment and configured to electrically stimulate human muscles; andan electric muscle stimulation unit connected to the plurality of electrodes and configured to provide electrical power to the plurality of electrodes.2. The device as claimed in claim 1 , wherein the electric muscle stimulation unit is programmable via input controls.3. The device as claimed in claim 1 , further comprising a plurality of contact sensors connected to the wearable garment and configured to detect a pressure against a back of a user and to send a pressure signal to the electric muscle stimulation unit.4. The device as claimed in claim 3 , wherein the plurality of contact sensors comprises a plurality of binary contact switches.5. The device as claimed in claim 3 , wherein the electric muscle stimulation unit is configured to provide electrical power to the plurality of electrodes at least in part due to the pressure signal from the plurality of contact sensors.6. The device as claimed in claim 5 , wherein the electric muscle stimulation unit is configured to derive a pressure profile against the back of the user and to provide a profile of electrical power to the plurality of electrodes according to both the pressure profile and an input signal input by the user.7. A method of correcting poor posture claim 5 , comprising:{'claim-ref': {'@idref': 'CLM-00001', 'claim 1'}, 'providing the device as claimed in ;'}donning the wearable garment; andactivating the electric muscle stimulation ...

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Номер записи: 16
28-11-2013 дата публикации

VAGAL NERVE STIMULATION TO AVERT OR TREAT STROKE OR TRANSIENT ISCHEMIC ATTACK

Номер: US20130317580A1
Автор: Errico Joseph P., Simon Bruce J.
Принадлежит: ElectroCore, LLC

Devices, systems and methods are disclosed for treating or preventing a stroke and/or a transient ischemic attack in a patient. The methods comprise transmitting impulses of energy non-invasively to selected nerve fibers, particularly those in a vagus nerve. Vagus nerve stimulation is used to modulate the release of GABA, norepinephrine, and/or serotonin, thereby providing neuroprotection to the patient; to modulate the activity of resting state neuronal networks, particularly the sensory-motor network or resting state networks containing the insula; and to avert a stroke or transient ischemic attack that has been forecasted. 1. A method of treating or preventing a stroke and/or a transient ischemic attack in a patient , comprising:positioning a device adjacent to a skin surface of the patient;generating one or more electrical impulses with said device; andtransmitting the electrical impulses to selected nerve fibers in the patient, wherein the electrical impulses are sufficient to modify the nerve fibers, such that the stroke and/or transient ischemic attack in the patient is treated or prevented.2. The method of wherein the transmitting step comprises transmitting the electrical impulses from one or more electrodes through a conducting medium within the device.3. The method of wherein the electrical impulses are transmitted transcutaneously through an outer skin surface of the patient to generate an electrical impulse at or near the selected nerve fibers.4. The method of further comprising generating an electrical field at or near the device and shaping the electrical field such that the electrical field is sufficient to modulate a nerve fiber at the target region claim 3 , and wherein the electric field is not sufficient to substantially modulate a nerve or muscle between the outer skin surface and the target region.5. The method of wherein the device comprises a signal generator claim 1 , and one or more electrodes coupled to the signal generator.6. The method ...

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Номер записи: 17
28-11-2013 дата публикации

METHODS AND DEVICES RELATING TO NON-INVASIVE ELECTRICAL NERVE STIMULATION

Номер: US20130317581A1
Автор: Redington Andrew
Принадлежит: THE HOSPITAL FOR SICK CHILDREN

The invention provides, in certain aspects, methods and devices relating to the use of non-invasive electrical nerve stimulation in subjects to reduce ischemic and/or reperfusion injury and restenosis, and to improve physical performance. 1. A method comprisingperforming non-invasive electrical nerve stimulation on a subject to reduce ischemic and/or reperfusion injury in the subject associated with an ischemic event, wherein the non-invasive electrical nerve stimulation is performed on the subject repeatedly after the ischemic event.2. The method of claim 1 , wherein the subject is having a myocardial infarction.3. The method of claim 2 , wherein non-invasive electrical nerve stimulation is also performed during the myocardial infarction.4. The method of claim 2 , wherein the non-invasive electrical nerve stimulation is performed during the myocardial infarction and then every day claim 2 , every two days claim 2 , or every three days after the myocardial infarction.5. The method of claim 2 , wherein the non-invasive electrical nerve stimulation is continued for 1 month after the myocardial infarction.69.-. (canceled)10. The method of claim 1 , wherein the subject is having surgery.11. The method of claim 10 , wherein the non-invasive electrical nerve stimulation is also performed during the surgery.12. The method of claim 10 , wherein the non-invasive electrical nerve stimulation is performed during the surgery and then every day claim 10 , every two days claim 10 , or every three days after the surgery.13. The method of claim 10 , wherein the non-invasive electrical nerve stimulation is continued for 1 month after the surgery.14. The method of claim 10 , wherein the surgery is cardiovascular surgery.15. The method of claim 1 , wherein the non-invasive electrical nerve stimulation is 1 claim 1 , 2 claim 1 , 3 claim 1 , 4 claim 1 , or 5 cycles of a nerve stimulation period followed by a rest period.16. The method of claim 15 , wherein the nerve stimulation period ...

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Номер записи: 18
19-12-2013 дата публикации

METHOD AND SYSTEM OF STIMULATION OF NERVE TISSUE WITH A SEQUENCE OF SPATIALLY DISTRIBUTED RESONANT SUB-THRESHOLD ELECTRICAL STIMULI

Номер: US20130338743A1
Автор: Starobin Joseph M., Varadarajan Vivek
Принадлежит: The University of North Carolina Greensboro

The present invention provides a method of stimulating an excitable tissue (e.g., in vitro, in vivo) with a primary electrical stimulus through a primary electrode at a primary stimulation frequency, to produce a propagating action potential in the excitable tissue. The invention is carried out by concurrently stimulating the excitable tissue with a secondary electrical stimulus through at least one secondary electrode at a secondary stimulation frequency. The primary and secondary stimulation frequencies are preferably different from one another. The secondary electrical stimulus preferably has an amplitude not more than one third that of the primary electrical stimulus. Preferably, propagation of the action potential in the excitable tissue is enhanced (e.g., when propagation of action potentials in the tissue is otherwise unstable, partially blocked, or fully blocked). Apparatus for carrying out the method is also described. 1. In a method of stimulating an excitable tissue with a primary electrical stimulus through a primary electrode at a primary stimulation frequency , to produce a propagating action potential in said excitable tissue , the improvement comprising:concurrently stimulating said excitable tissue with a secondary electrical stimulus through at least one secondary electrode at a secondary stimulation frequency;wherein said primary and secondary stimulation frequencies are different from one another;and wherein said secondary electrical stimulus has an amplitude not more than one third that of said primary electrical stimulus;so that propagation of said action potential in said excitable tissue is enhanced.2. The method of claim 1 , wherein said primary stimulation frequency is from 1 Hertz up to 20 Hertz3. The method of claim 1 , wherein said secondary stimulation frequency is from 1 to 15 percent greater than claim 1 , or 1 to 15 percent less than claim 1 , said primary stimulation frequency.4. The method of claim 1 , wherein secondary electrical ...

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Номер записи: 19
26-12-2013 дата публикации

Multi-Layered Heat Therapy and Electrotherapy Back Pad Device

Номер: US20130345778A1
Автор: John L. Woods
Принадлежит: Individual

A multi-layered therapy pad is provided having a comfortable and supportive structure that houses heat therapy and electrotherapy means for treating back injuries and sores while an individual lies thereon. The pad comprises a first and second outermost layer of low-resilience polyurethane foam sandwiching an internal layer of higher density foam, which also supports electrical connections between the therapy controller, the power source, and the two therapy means within the pad. The electrotherapy means comprises static or tethered electrodes that apply pulsing electric current directly onto the user's back for stimulation and easing of back pain, while the heat therapy is applied using a resistance heating element within the pad, which heats a majority of the pad for applying heat to the user's back. The operation of the therapy means is controlled by an external controller, while power in received through an external source or an internal battery pack.

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Номер записи: 20
26-12-2013 дата публикации

Disposable Internal Defibrillation Electrodes

Номер: US20130345784A1
Автор: Coggins Scott R.
Принадлежит: COVIDIEN LP

A disposable electrode paddle assembly is provided and includes a shaft having a proximal end and a distal end; a handle assembly supported at the proximal end of the shaft; a spoon supported at the distal end of the shaft; an electrical conductor extending from the handle assembly and establishing an electrical connection at the spoon; and an electrode assembly selectively, electrically connectable to the electrical connection provided at the spoon; wherein the electrode assembly includes a layer of silver/silver-chloride (Ag/AgCl) having one of an increasing and decreasing density extending in a radially outward direction. 132-. (canceled)33. A disposable electrode paddle assembly , comprising:a shaft having a proximal end and a distal end;a handle assembly supported at the proximal end of the shaft;a spoon supported at the distal end of the shaft; a lead wire having a first end and a second end;', 'a first substrate comprising an electrically insulated material;', 'a second substrate comprising a conductive material;', 'a third substrate comprising a carbon/vinyl film;', 'a fourth substrate comprising a conductive hydrogel; and', 'a single layer of silver/silver-chloride (Ag/AgCl) interposed between adjacent substrates, the layer of silver/silver-chloride (Ag/AgCl) having one of an increasing or a decreasing density extending in a radially outward direction, the silver/silver-chloride layer (Ag/AgCl) being in direct contact with the first end of the lead wire; and, 'an electrode assembly selectively, electrically connectable to an electric connection provided at the spoon; the electrode assembly comprisingan electrical conductor extending from the handle assembly and establishing an electrical connection with the second end of the lead wire at the spoon.34. The disposable electrode paddle assembly of wherein the electrically insulated material is X-ray transparent material.35. The disposable electrode paddle assembly of wherein the layer of the silver/silver- ...

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Номер записи: 21
20-03-2014 дата публикации

METHODS AND DEVICES FOR TREATING PRIMARY HEADACHE

Номер: US20140081071A1
Автор: Errico Joseph P., Raffle John T., Simon Bruce J.
Принадлежит: ElectroCore, LLC

Non-invasive electrical nerve stimulation devices and magnetic stimulation devices are disclosed, along with methods of treating medical disorders using energy that is delivered noninvasively by such devices. The disorders comprise migraine and other primary headaches such as cluster headaches, including sinus symptoms that resemble an immune-mediated response (“sinus” headaches), irrespective of whether those symptoms arise from an allergy that is co-morbid with the headache. The disclosed methods may also be used to treat other disorders that may be co-morbid with migraine headaches, such as anxiety disorders. In preferred embodiments of the disclosed methods, one or both of the patient's vagus nerves are stimulated non-invasively. In other embodiments, parts of the sympathetic nervous system and/or the adrenal glands are stimulated. 1. A device for treating a headache in a patient comprising:a housing having an electrically permeable contact surface for contacting an outer skin surface of a patient; andan energy source within the housing configured to generate an electric field sufficient to transmit an electric current through the outer skin surface of the patient to a nerve at a target region within the patient, wherein the electric current is sufficient to modulate serotonergic neurons in the raphe nucleus and to at least partially relieve pain associated with the headache.2. The device of wherein the energy source comprises one or more electrodes coupled to a signal generator within the housing.3. The device of further comprising a conducting medium within the housing between electrodes and the electrically permeable contact surface.4. The device of further comprising a battery within the housing for providing energy to the signal generator.5. The device of wherein the electric field comprises bursts of pulses with a frequency of about 5 to about 100 bursts per second.6. The device of wherein the electric field comprises bursts of about 1 to about 20 pulses ...

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Номер записи: 22
20-03-2014 дата публикации

PUNCTUAL STIMULATION DEVICE

Номер: US20140081368A1
Автор: Szeles Josef Constantin
Принадлежит:

The invention relates to a device for the punctual stimulation of endings, located in the region of the ears, of nerves leading to brain stem nuclei, and device () having a battery-powered therapeutic current generator (), which is arranged in a housing () to be worn in the ear region and is provided with an electronic circuit that forms a low-frequency therapeutic current, and said device also having at least one flexible line () proceeding from the therapeutic current generator () for connecting to an electrode to be positioned at a nerve ending and having a base electrode (), which is likewise connected to the therapeutic current generator and by means of which the therapeutic circuit leading across the former electrode is closed, wherein the device (), at least by means of an external part of said device (), can be adapted to the shape of the body point of patient intended for the positioning of the device due to a mechanically pliable structure. 1. A device for point stimulation of endings of nerves that are in region of the ears and that lead to brain stem nuclei , comprising:a housing configured to be worn in a region of a ear and that is provided with an electronic circuit that forms a low-frequency therapeutic current,a battery-powered therapeutic current generator that is arranged within said housing,at least one flexible cord proceeding from the therapeutic current generator for connecting to an electrode configured to be positioned on one of more of said nerve endings, anda base electrode, also connected to the therapeutic current generator, via which the therapeutic current circuit leading across the aforesaid electrode is closed, wherein due to a mechanically pliable structure, the device, or at least an exterior portion of this device, is configured to be adapted to the shape of a body part of a patient provided for positioning it.2. The device in accordance with claim 1 , wherein the base electrode disposed in the therapeutic circuit is flat and ...

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Номер записи: 23
20-03-2014 дата публикации

HEADACHE-TREATMENT DEVICE WITH GEL DISPENSING KIT AND METHOD

Номер: US20140081369A1
Автор: Bermudez Viridiana Rodríguez, Covalin Alejandro, Guzmán Rocío, Riveros Omar Mendizabal, Sosa Victor Manuel Valencia, Suárez Juan Manuel González
Принадлежит:

Electrical-stimulation device with gel-dispensing kit, and a method of making and using the parts of the kit. A convenient and easy-to-use system to provide an electrically conductive path from a transcutaneous electrical nerve stimulation (TENS) device to the skin surface of a patient to supply transcutaneous stimulation, even through hair. The invention provides improved prevention and treatment for headache, depression, alertness, attention deficit hyperactivity disorder (ADHD), epilepsy, anxiety, post-traumatic stress disorder (PTSD), and behavioral and/or other disorders. Some embodiments provide a headache-treatment system that includes an electrode base shaped to conform to a back of a human head; a TENS having projecting spring electrodes each connected to the electrode base; means for holding an electrically conductive gel in a plurality of sealed pockets; and means for unsealing the means for holding the gel and applying the gel substantially simultaneously to the projecting spring electrodes. 1. A method comprising:providing a transcutaneous electrical nerve stimulator (TENS) headache-treatment system having a first plurality of projecting spring electrodes and operating the TENS with the first plurality of projecting spring electrodes in direct contact with a human user's head;providing a sealed gel dispenser separate from the TENS headache-treatment system and having a first plurality of pockets each containing an electrically conductive gel, the gel-containing pockets being covered by a membrane seal;unsealing the sealed gel dispenser;applying the gel from the dispenser substantially simultaneously to a distal end of each of the first plurality of projecting spring electrodes; andseparating and detaching the first plurality of pockets from the first plurality of projecting spring electrodes after the gel is applied and before TENS is operated with the distal ends of the first plurality of projecting spring electrodes in direct contact with the human ...

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Номер записи: 24
06-01-2022 дата публикации

VAGAL NERVE STIMULATION FOR TREATING CENTRAL NERVOUS SYSTEM DISORDERS

Номер: US20220001166A1
Автор: Errico Joseph P., Simon Bruce J.
Принадлежит:

Devices, systems and methods are disclosed for treating one or more symptoms of central nervous system disorders in a patient, such as anxiety disorders, fibromyalgia, traumatic brain injury, PTSD, and others. A method includes positioning a contact surface of a device in contact with an outer skin surface of patient and applying an electrical impulse transcutaneously from the device through the outer skin surface of the patient to a vagus nerve in the patient for about 90 seconds to about 3 minutes. The electrical impulse is sufficient to modify the vagus nerve such that the symptoms of the central nervous system disorder are reduced. For chronic treatment of such disorders, a stimulation protocol is provided that includes two or more doses administered per day for a period of time sufficient to relieve the symptoms. 1. A device for treating symptoms of a central nervous system disorder in a patient , the device comprising:one or more electrodes configured for contacting an outer skin surface of the patient; andan energy source coupled to the electrodes, wherein the energy source is configured to generate at least one electrical impulse and to transmit the at least one electrical impulse transcutaneously from the electrodes through the outer skin surface of the patient to a vagus nerve in the patient according to a stimulation protocol that includes at least two doses administered each day for a plurality of days, wherein the doses each have a duration of about ninety seconds to about 3 minutes; andwherein the electrical impulse is sufficient to modify the vagus nerve such that the symptoms of the central nervous system disorder are reduced.2. The device of claim 1 , wherein the energy source is wirelessly coupled to the one or more electrodes.3. The device of claim 1 , further comprising an electrical connector coupling the energy source to the one or more electrodes.4. The device of claim 1 , wherein the one or more electrodes are configured for attachment to the ...

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Номер записи: 25
06-01-2022 дата публикации

WEARABLE THERAPEUTIC DEVICE

Номер: US20220001167A1
Автор: Kaib Thomas E., Oskin Emil, Volpe Shane S.
Принадлежит:

A wearable monitoring and therapeutic device includes at least two sensing electrodes. Each sensing electrode includes a metallic surface integrated in a garment. The device includes at least two therapy electrodes. Each of the at least two therapy electrodes includes a receptacle, and each receptacle includes at least one dose of conductive fluid. The device includes the garment. The garment includes a fabric that is stretchable and that is breathable and/or moisture wicking, and conductive wiring configured to at least partially electrically connect that at least two sensing electrodes to at least one defibrillator component. The device includes the at least one defibrillator component. The at least two therapy electrodes are configured to provide an electric shock to the subject. Prior to the application of the electric shock, each receptacle is configured to release the conductive fluid from the receptacle. 131-. (canceled)32. A wearable monitoring and therapeutic device comprising:at least two sensing electrodes, each sensing electrode comprising a metallic surface integrated in a garment; wherein each of the at least two therapy electrodes comprises a receptacle, and', 'wherein each receptacle comprises at least one dose of conductive fluid;, 'at least two therapy electrodes,'} a fabric that is stretchable and that is breathable and/or moisture wicking, and', 'conductive wiring configured to at least partially electrically connect the at least two sensing electrodes to at least one defibrillator component; and, 'the garment, wherein the garment is configured to be worn about a torso of a subject, the garment comprising'} wherein the at least one defibrillator component comprises a power source,', 'wherein the at least two sensing electrodes electrically connected to the at least one defibrillator component at least partially via the conductive wiring are configured to monitor and ECG of the subject,', 'wherein the at least two therapy electrodes are configured ...

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Номер записи: 26
06-01-2022 дата публикации

BODY JOINT SUPPORT DEVICE WITH INFLATABLE AIRBAG, ELECTRODE OR BOTH

Номер: US20220001178A1
Автор: HO Hoi Ming Michael
Принадлежит:

A body joint support device capable of abutting against at least one body joint and accommodating in configuration both to the bending and non-bending states of the body joint includes a covering structure, a control device, and at least one electrode pad unit and/or inflatable airbag. The covering structure can be worn to the body joint, the electrode pad unit is provided on the inner surface of the covering structure, and the control device is provided on the outer surface of the covering structure. The control device can transmit current to the electrode pad unit so that the electrode pad unit outputs current to stimulate and/or heat muscles. When a body joint moves, the force produced by the covering structure can press the electrode pad unit tightly against the skin at the body joint, so that the electrode pad unit does not become loose due to frequent body joint movement. 1. A body joint support device , comprising:a covering structure configured to be worn at at least one body joint and press a skin of the body joint that is in a bending state against an inner surface of the covering structure by a pressing force exerted by the covering structure;at least one electrode pad unit disposed on the inner surface of the covering structure and configured to abut against the skin of the body joint through the pressing force; anda control device configured to be fixed on the covering structure and transmit current to the electrode pad unit for the electrode pad unit to transmit current to stimulate or to heat muscle.2. The body joint support device according to claim 1 , the covering structure comprising:a covering body, wherein the electrode pad unit is disposed on an inner surface thereof and the control device is disposed on an outer surface thereof;at least one airbag located in the covering body and configured to expand along a direction toward the inner surface of the covering body so that the inner surface of the covering body exerts the pressing force to the ...

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Номер записи: 27
04-01-2018 дата публикации

Method for Treatment of Internal Disorders Via Activation of Dermatomal Nervous Receptors

Номер: US20180000681A1
Автор: Jaudy Gilbert
Принадлежит:

A system and method for treating neural lesions is disclosed. The inventive method comprises determining the location of a neural lesion in a patient and applying a selected modality to a dermatomal region on the patient to compensate for the existence of the neural lesion. The selected modality includes the implementation of a method or device to activate any number of receptors located in the skin of the patient. The modality implemented in the correct dermatomal region initiates a somatosensory signal to the brain which responds with a corresponding motor signal to the affected area. Proper implementation of the selected modality supports neuroplasticity and neurogenesis to create a permanent solution to overcome the neural lesion. 1) A method for treating a neural lesion comprisinga) determining the existence of a neural lesion in a subject; 'i) wherein said dermatome is innervated by a nerve connected to a neural pathway containing said neural lesion;', 'b) selecting a dermatome on said subject'} 'i) wherein said therapeutic modality is sufficient to activate neuroplasticity via synaptogenesis within collateral branches of said neural pathway.', 'c) applying a therapeutic modality to said dermatome'}2) The method as in wherein said dermatome is selected from a group consisting of: C2 claim 1 , C3 claim 1 , C4 claim 1 , C5 claim 1 , T1 claim 1 , T2 claim 1 , T3 claim 1 , T4 claim 1 , T5 claim 1 , T6 claim 1 , T7 claim 1 , T8 claim 1 , T9 claim 1 , T10 claim 1 , T11 claim 1 , T12 claim 1 , L1 claim 1 , L2 claim 1 , L3 claim 1 , L4 claim 1 , L5 claim 1 , S1 claim 1 , S2 claim 1 , S3 claim 1 , S4 claim 1 , and S5.3) The method as in wherein said therapeutic modality is selected from a group consisting of:a) applying consistent pressure over a predetermined period of time with a reflex hammer;b) applying a rhythmic vibrational force over a predetermined period of time with a reflex hammer;c) applying a force over a predetermined period of time with a tuning fork;d) ...

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Номер записи: 28
07-01-2016 дата публикации

Magnetic Field Treatment Techniques

Номер: US20160001074A1
Автор: Parow Aimee, Renshaw Perry, Rohan Michael L.
Принадлежит:

The invention involves enhancing brain function by stimulating the brain using magnetic fields. Applications of the new methods include improving the condition of individuals with cognitive disorders, such as depression, and studying the effects of neural stimulation using induced electric fields. These techniques can avoid deleterious effects of psychotropic pharmaceutical treatments, and provide a relatively safe, comfortable, inexpensive means of direct cranial stimulation. 120-. (canceled)21. A method of treating a patient , comprising the steps of:generating an electric field comprising a series of electric field pulses having a frequency of at least about 100 Hz, wherein each pulse has a single polarity and the pulses are separated by periods of substantially no electric field; andsubjecting the patient's head to the electric field.22. The method of claim 21 , wherein the frequency of the series of electric field pulses is about 1 kHz.23. The method of claim 21 , wherein the electric field pulses have an amplitude less than about 10 V/m.2420. The method of claim claim 21 , wherein the electric field pulses have an amplitude less than about 5 V/m.25. The method of claim 21 , wherein the electric field is substantially unidirectional over at least a region of the patient's brain.26. The method of claim 21 , wherein successive electric field pulses have alternating polarity.27. The method of claim 21 , wherein the duration of each electric field pulse is less than or equal to about 10 milliseconds.2820. The method of claim claim 21 , wherein the duration of each electric field pulse is less than or equal to about 1 millisecond.2920. The method of claim claim 21 , wherein the duration of each electric field pulse is about 250 microseconds.30. A method of treating a patient claim 21 , comprising the steps of:generating an electric field comprising a series of electric field pulses, wherein the pulses have a duration less than about 10 milliseconds, and wherein each ...

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Номер записи: 29
07-01-2021 дата публикации

AUTONOMOUS NEUROSTIMULATION UNIT

Номер: US20210001111A1
Автор: SEIKAI ARMENTA Aitaro
Принадлежит:

An autonomous neurostimulation unit used in the modulation of the nervous system is provided and has: at least one pair of pads, each formed by at least one inner layer of ceramic; an intermediate layer; and a conductive alloy coating. The material of the layer of coating is different and has different conductivity in each of the pads of the pair. The unit can be used in the modulation of the nervous system, with neurostimulation methods that are adapted to each patient. 1. An autonomous neurostimulation unit , used in the modulation of the nervous system comprising at least one pair of pads , each pad is structured of at least:a) an inner layer of ceramic;b) an intermediate layer; andc) a conductive alloy coating.2. The autonomous neurostimulation unit according to wherein the conductive coating comprises a material that is different and wherein each pad of the pair of pads has different conductivity. The object of the invention refers to an autonomous neurostimulation unit used in the modulation of the nervous system.The information processing system of the organism is based on the transmission of sensory impulses produced by neural ion exchange. These neural impulses or electrophysiological excitations are transmitted through different channels or routes of the nervous system. These routes or channels are the different trajectories of the nerve branches that come from the spinal column and that connect from one point of the organism to another. That in correct operation of electrophysiological transmission have an optimal frequency, obtaining perfect emission of the neural impulses that allow the maximum efficiency of the channels of the nervous system.The processing of information by the human organism of stimulus from the outside world through an INPUT of information is processed by our sensory organs, in this case the nervous system through the channels or routes of the peripheral nervous system. This information is processed by neural impulses that reflect a ...

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Номер записи: 30
07-01-2021 дата публикации

ELECTRICAL NERVE STIMULATOR

Номер: US20210001120A1
Автор: Hatch William, Lindsley Ryan, Thorne Steven
Принадлежит: Arctoro Medical, LLC

This disclosure generally relates to a device, method, and system for diagnosing and treating nerve injuries with electrical stimulation. A probe is provided which connects to a nerve stimulator system which measures voltage and electrical current applied to a living body to detect a nerve injury location. A processor within the nerve stimulator system may adjust the voltage and current output to numb or deaden an injured nerve. 1. A probe , comprising:an internal switch which is operable by a sliding core to initiate electrical conductivity to a tip of the probe, wherein the sliding core slides on one or more runners within the probe, andan electrical stimulator disposed at a tip of the probe which is selectively electrified by applying the tip of the probe to a living body which causes the sliding core to interface with the switch.2. The probe of claim 1 , wherein the probe is contained within a casing.3. The probe of claim 1 , wherein the electrical stimulator is made from copper.4. The probe of claim 1 , further comprising a safety catch disposed at a tip end of the probe.5. The probe of claim 1 , wherein the internal switch initiates electrical conductivity when pressure is applied to the tip of the probe.6. The probe of claim 5 , wherein the internal switch includes a spring.7. The probe of claim 6 , wherein the pressure applied to the tip of the probe causes the sliding core to slide into the probe and initiates electrical conductivity to the tip of the probe.8. The probe of claim 1 , wherein a wire is disposed between the runners.9. The probe of claim 1 , wherein the probe is connected to a cable which provides current at a particular voltage to the electrical stimulator.10. The probe of claim 1 , wherein the provided current and particular voltage are adjustable.11. A nerve stimulating system claim 1 , comprising:a processor which controls a voltage and current output of the nerve stimulating system;a probe having a tip which includes an electrical ...

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Номер записи: 31
07-01-2021 дата публикации

Detection and Treatment of Obstructive Sleep Apnea

Номер: US20210001122A1
Автор: ALTMANN William C., TOONG Hoo-min D.
Принадлежит:

A treatment for obstructive sleep apnea (“OSA”) of a user includes affixing a patch externally on a dermis of the user, the patch including a flexible substrate, an adhesive on a first side adapted to adhere to the dermis of the user, a processor directly coupled to the substrate, and electrodes directly coupled to the substrate. The treatment includes detecting an occurrence of OSA and activating the patch in response to the detecting, the activating including generating an electrical stimuli via the electrodes to activate the genioglossus muscle of the user. 1. A method of treatment for obstructive sleep apnea (OSA) of a user , the method comprising:affixing a patch externally on a dermis of the user, the patch comprising a flexible substrate, a processor directly coupled to the substrate, and electrodes directly coupled to the substrate;detecting an occurrence of OSA; andactivating the patch in response to the detecting, the activating comprising generating an electrical stimuli via the electrodes to activate a genioglossus muscle of the user.2. The method of claim 1 , a placement of the patch on the user causing the activating to avoid activation of a styloglossus muscle of the user.3. The method of claim 1 , the electrical stimuli comprising adjustable parameters comprising a pulse high time claim 1 , a pulse low time claim 1 , a pulse period claim 1 , and a pulse amplitude.4. The method of claim 3 , the adjustable parameters automatically adjusted during the treatment based on feedback from one or more sensors.5. The method of claim 2 , the placement comprises affixing the patch to a neck of the user on or near a submental triangle of the user via an adhesive.6. The method of claim 2 , the placement comprises affixing the patch near a sural nerve on a leg of the user.7. The method of claim 1 , the electrical stimuli causing a tongue of the user to move.8. The method of claim 2 , the placement causing the electrical stimuli to cross axially along a geniohyoid ...

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Номер записи: 32
07-01-2021 дата публикации

Auricular nerve field stimulation device

Номер: US20210001124A1
Автор: Christopher R. Brown, Gary M. Peterson
Принадлежит: Innovative Health Solutions Inc

An auricular nerve field stimulation device may include a first plurality of electrodes arranged to contact a ventral aspect of an auricle, a second plurality of electrodes arranged to contact a dorsal aspect of the auricle, and electrical circuitry coupled to the electrodes and configured to selectively apply electrical stimulation signals to the electrodes to cause a first set of trans-auricular currents to flow through the auricle between the first plurality of electrodes and respective ones of the second plurality of electrodes paired therewith according to a first pairing, and to cause a second set of trans-auricular currents to flow through the auricle between the first plurality of electrodes and respective ones of the second plurality of electrodes paired therewith according to a second pairing different from the first pairing, the first and second sets of trans-auricular currents to stimulate at least one auricular nerve field within the auricle.

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Номер записи: 33
04-01-2018 дата публикации

Devices, systems and methods for the treatment of medical disorders

Номер: US20180001077A1
Автор: Christopher M. Degiorgio, Ian A. Cook
Принадлежит: UNIVERSITY OF CALIFORNIA

The present disclosure relates to methods, devices and systems used for the treatment of medical disorders via stimulation of the superficial elements of the trigeminal nerve. More specifically, cutaneous methods of stimulation of the superficial branches of the trigeminal nerve located extracranially in the face, namely the supraorbital, supratrochlear, infraorbital, auriculotemporal, zygomaticotemporal, zygomaticoorbital, zygomaticofacial, infraorbital, nasal and mentalis nerves (also referred to collectively as the superficial trigeminal nerve) are disclosed herein.

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Номер записи: 34
04-01-2018 дата публикации

Arrays for Longitudinal Delivery of TTFields to a Body

Номер: US20180001078A1
Автор: BOMZON Zeev, HERSHKOVICH Hadas Sara, KIRSON Eilon, WASSERMAN Yoram
Принадлежит: Novocure Limited

Tumors in portions of a subject's body that have a longitudinal axis (e.g., the torso, head, and arm) can be treated with TTFields by affixing first and second sets of electrodes at respective positions that are longitudinally prior to and subsequent to a target region. An AC voltage with a frequency of 100-500 kHz is applied between these sets of electrodes. This imposes an AC electric field with field lines that run through the target region longitudinally. The field strength is at least 1 V/cm in at least a portion of the target region. In some embodiments, this approach is combined with the application of AC electric fields through the target region in a lateral direction (e.g., front to back and/or side to side) in order to apply AC electric fields with different orientations to the target region. 1. An apparatus for treating a target region in a subject's body with TTFields , the target region being located in a portion of the subject's body that has a longitudinal axis , the apparatus comprising:a first set of one or more capacitively coupled electrodes;a first substrate configured to hold the first set of one or more electrodes against the subject's body so that the first set of one or more electrodes surrounds a first part of the subject's body at a position that is longitudinally prior to the target region;a second set of one or more capacitively coupled electrodes;a second substrate configured to hold the second set of one or more electrodes against the subject's body so that the second set of one or more electrodes surrounds a second part of the subject's body at a position that is longitudinally subsequent to the target region;a third set of one or more capacitively coupled electrodes;a third substrate configured to hold the third set of one or more electrodes against the subject's body on a first side of the target region, at a position that is longitudinally between the first set of one or more electrodes and the second set of one or more electrodes;a ...

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Номер записи: 35
04-01-2018 дата публикации

FLEXIBLE SHEET FOR NEUROMUSCULAR STIMULATION

Номер: US20180001086A1
Автор: Bartholomew John, Friend Jeffrey
Принадлежит:

A flexible sheet for neurostimulation is described having a flexible non-conductive substrate matrix in which electrodes are embedded along a lower surface. Electrically conductive wires extend from the electrodes through the flexible substrate to another exterior surface of the substrate. Methods of making the flexible sheet and making a device using the flexible sheet are also disclosed. 1. A flexible sheet , comprising:a non-conductive, flexible substrate;a plurality of electrodes embedded within the flexible substrate; andelectrically-conductive wires running through the flexible substrate from a common exterior surface of the flexible substrate to each electrode.2. (canceled)3. (canceled)4. (canceled)5. The flexible sheet of claim 2 , wherein the flexible substrate comprises a top surface claim 2 , a bottom surface opposite the top surface claim 2 , and a plurality of side surfaces; wherein the plurality of electrodes is located on the bottom surface; and wherein the wires extend to one of the side surfaces.6. (canceled)7. (canceled)8. (canceled)9. The flexible sheet of claim 1 , further comprising a sensor embedded within the substrate.10. (canceled)11. (canceled)12. (canceled)13. The flexible sheet of claim 1 , further comprising a mechanical fastener embedded in the substrate claim 1 , for holding the flexible sheet in the form of a sleeve.14. (canceled)15. The flexible sheet of claim 1 , further comprising insulating ceramic dispersed throughout the flexible substrate.16. A system for muscular neurostimulation claim 1 , comprising:{'claim-ref': {'@idref': 'CLM-00001', 'claim 1'}, 'an inner sleeve formed from the flexible sheet of ; and'}a compression sleeve surrounding the inner sleeve.17. A flexible sheet claim 1 , comprising:a fabric substrate;a plurality of conductive components on a bottom surface of the fabric substrate; anda plurality of non-conductive components on the bottom surface of the fabric substrate18. (canceled)19. The flexible sheet of ...

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Номер записи: 36
02-01-2020 дата публикации

Arrays for Longitudinal Delivery of TTFields to a Body

Номер: US20200001069A1
Автор: BOMZON Zeev, HERSHKOVICH Hadas Sara, KIRSON Eilon, WASSERMAN Yoram
Принадлежит: Novocure GmbH

Tumors in portions of a subject's body that have a longitudinal axis (e.g., the torso, head, and arm) can be treated with TTFields by affixing first and second sets of electrodes at respective positions that are longitudinally prior to and subsequent to a target region. An AC voltage with a frequency of 100-500 kHz is applied between these sets of electrodes. This imposes an AC electric field with field lines that run through the target region longitudinally. The field strength is at least 1 V/cm in at least a portion of the target region. In some embodiments, this approach is combined with the application of AC electric fields through the target region in a lateral direction (e.g., front to back and/or side to side) in order to apply AC electric fields with different orientations to the target region. 1. A kit of electrodes for treating a target region in a subject's body with TTFields , the target region being located in a portion of the subject's body that has a longitudinal axis , the apparatus comprising:a first plurality of capacitively coupled electrodes wired together in parallel, in series, or in a parallel/series combination;a first band-shaped substrate configured to hold the first plurality of electrodes against the subject's body so that the first plurality of electrodes surrounds a first part of the subject's body at a position that is longitudinally prior to the target region;a second plurality of capacitively coupled electrodes wired together in parallel, in series, or in a parallel/series combination;a second band-shaped substrate configured to hold the second plurality of electrodes against the subject's body so that the second plurality of electrodes surrounds a second part of the subject's body at a position that is longitudinally subsequent to the target region;a third plurality of capacitively coupled electrodes wired together in parallel, in series, or in a parallel/series combination;a third substrate configured to hold the third plurality of ...

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Номер записи: 37
02-01-2020 дата публикации

NON-INVASIVE VAGAL NERVE STIMULATION TO TREAT DISORDERS

Номер: US20200001083A1
Автор: Errico Joseph P., Raffle John T., Simon Bruce J.
Принадлежит:

Devices, systems and methods are disclosed for treating a variety of diseases and disorders that are primarily or at least partially driven by an imbalance in neurotransmitters in the brain, such as asthma, COPD, depression, anxiety, epilepsy, fibromyalgia, and the like. The invention involves the use of an energy source comprising magnetic and/or electrical energy that is transmitted non-invasively to, or in close proximity to, a selected nerve to temporarily stimulate, block and/or modulate the signals in the selected nerve such that neural pathways are activated to release inhibitory neurotransmitters in the patient's brain. 1. A method for treating a disorder in a patient , the method comprising:positioning a device in contact with an outer skin surface of a patient;generating, via the device, an electric current external to the patient; andtransmitting, via the device, the electric current transcutaneously through the outer skin surface to a vagus nerve within the patient, wherein the electric current has a frequency of between about 1000 Hz and about 10,000 HZ and a duty cycle between about 1% and about 10%.2. The method of wherein the frequency is between about 4000 Hz and about 6000 HZ.3. The method of wherein the frequency is about 5000 Hz.4. The method of wherein the duty cycle is between about 2% and about 5%.5. The method of wherein the duty cycle is about 2.5%.6. The method of wherein the electrical current includes bursts of pulses having a burst duration of between about 0.1 and 10 milliseconds and a burst frequency of between about 10-50 Hz.7. The method of wherein the burst duration is between 2 and 6 milliseconds.8. The method of wherein the burst frequency is between 10 and 35 Hz.9. The method of wherein the electrical impulses generate an electric field at the vagus nerve above a threshold for generating action potentials within A and B fibers of the vagus nerve and below a threshold for generating action potentials within C fibers of the vagus ...

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Номер записи: 38
02-01-2020 дата публикации

UNIVERSAL MODULARIZED PORTABLE THERAPEUTIC LIMB AND BODY REST PAIN MANAGEMENT APPARATUS

Номер: US20200001084A1
Автор: Harrison, JR. Donald Ira
Принадлежит:

A universal modularized portable therapeutic limb and body rest pain management device is disclosed. The portable therapeutic pain management device is coupled with a biostable spring slap mechanism which allows the device to be adjusted to enclose a user's limb or body part at a convenient location. 1. A portable heat , cold , thermo-electro stimulation compression apparatus for pain management , the apparatus comprising:a layer including first, second, third and fourth portions having respective edges that are connected to each other while being spaced apart from each other by a separator;a therapeutic apparatus configured to be positioned between the layer and an extremity or body part of a user when the extremity or body part is positioned within an opening defined by the layer; anda biostable spring slap flap connected to the fourth portion of the layer; anda locking mechanism attached to the biostable spring slap flap; anda microchip disposed within the apparatus; anda touch screen controller; anda rechargeable battery pack; andan adjustable tripod stand;2. The portable thermo-electro stimulation compression apparatus recited in claim 1 , wherein the first portion is comprising kevlar claim 1 , nanowhiskers claim 1 , or nanoparticles wherein the Kevlar claim 1 , nanowhiskers claim 1 , or nanoparticles are eco-friendly and resistant to hot or cold temperature; the second portion comprising kinectic sand enclosed in a leak proof fabric claim 1 , the third portion is comprising canvas for support claim 1 , and the fourth portion comprising silicone or polypropylene snap rubber.3. The apparatus as recited in claim 1 , wherein the biostable spring slap is a tightening mechanism comprised of silicone or polypropylene snap rubber;4. The apparatus as recited in claim 1 , further comprising vibrators claim 1 , cooling and heating coils claim 1 , diathermy claim 1 , piezoelectric apparatus or a TENS unit disposed between the silicone or polypropylene snap rubber and the ...

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Номер записи: 39
04-01-2018 дата публикации

CONDUCTIVE GEL RELEASE AND DISTRIBUTION DEVICES

Номер: US20180001101A1
Автор: Ballard Dale, Hulings Robert J., Quinnell Scott D., Seman Ronald A.
Принадлежит:

A gel deployment device for use with an electrotherapy system is provided. The device includes a plurality of gel reservoirs disposed on a substrate, each of the plurality of gel reservoirs containing conductive gel. Each of the gel reservoirs are positioned adjacent to at least one seal such that the seal restricts flow of the conductive gel. The seal can be configured to release the conductive gel from the gel reservoir in response to pressure being applied about a perimeter of the seal at, for example, multiple points about the perimeter or substantially equally about the perimeter of the seal. In an example, each gel reservoir can be shaped such that the gel reservoir partially or fully surrounds a seal. In another example, multiple gel reservoirs can be arranged in clusters such that the multiple gel reservoirs are positioned about a single seal. 1. A gel deployment device for use with an electrotherapy system , the device comprising:a substrate;a plurality of gel reservoirs disposed on the substrate, each of the plurality of gel reservoirs comprising a volume of a conductive gel and positioned substantially adjacent to a seal;wherein the seal is configured to release the conductive gel from at least one of the plurality of gel reservoirs in response to pressure being applied about a perimeter of the seal; andat least one conductive surface configured to come into contact with the released conductive gel and to deliver a therapeutic current to a body of a patient.2. The device of claim 1 , wherein the conductive gel is capable of conducting the therapeutic current from the at least one conductive surface to the patient's skin.3. The device of claim 1 , wherein the at least one conductive surface comprises at least one opening configured to define an inner edge within the at least one conductive surface.4. The device of claim 1 , wherein the substrate comprises one or more ventilation holes configured to facilitate air flow through the gel deployment device.5. ...

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Номер записи: 40
05-01-2017 дата публикации

ELECTROTHERAPY DEVICE

Номер: US20170001004A1
Автор: RAMI MURILLO XAVIER
Принадлежит:

The invention relates to an electrotherapy device comprising: a plurality of active electrodes; a return electrode; and a plurality of voltage generators which are each connected to an active electrode; wherein said device comprises a controller for the voltage generators, which is provided with means for monitoring and/or varying the voltage supplied to each one of the active electrodes independently. 1. Electrotherapy device which comprises:a plurality of active electrodes;a return electrode; anda plurality of voltage generators each connected to an active electrode;characterised in that said device comprises a voltage generator controller which has means for monitoring and/or varying the voltage supplied to each of the active electrodes independently.2. Device according to claim 1 , characterised in that the voltage generator controller comprises means for monitoring and/or varying the phase of the voltage supplied to each of the active electrodes.3. Device according to claim 1 , characterised in that the voltage generator controller comprises means for monitoring and/or varying the frequency of the voltage supplied to each of the active electrodes.4. Device according to claim 1 , characterised in that through each of the active electrodes there is claim 1 , at most claim 1 , a current of 300 mA RMS.5. Device according to claim 1 , characterised in that for each of the voltage outputs of the voltage generators there is claim 1 , at most claim 1 , a voltage of 70 V RMS.6. Device according to claim 1 , characterised in that each of the outlets of the voltage generators has a maximum electric power of 50 W.7. Device according to claim 1 , characterised in that the signals generated by the voltage generators are sinusoidal signals claim 1 , with a harmonic distortion of less than 50%.8. Device according to claim 1 , characterised in that the signals generated by the voltage generators are signals with a frequency of between 100 kHz and 2 MHz.9. Device according to ...

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Номер записи: 41
03-01-2019 дата публикации

ENHANCED INFUSION-SITE PAIN-REDUCTION FOR DRUG-DELIVERY DEVICES

Номер: US20190001076A1
Автор: RAND Jacob, Rigby Jonathan, Solomon Ian
Принадлежит:

The present invention provides an infusion-patch comprising; a cannula; a base; at least one adhesive region in said base suitable for skin attachment; at least one skin-access area within said base; and at least one conduit in fluid connection with said at least one skin access area, wherein said at least one conduit in fluid connection with said at least one skin access area facilitates the transfer of an anesthetic substance within at least a first anesthetic-reservoir which may be removably attached and in fluid connection with said at least one contact area, promoting delivery of said anesthetic substance to said at least one skin-access areas, and wherein said anesthetic substance delivered to said skin-access areas may be at least partially replenished without removing said infusion-patch. Embodiments of the present invention include methods of administering a drug using the infusion-patch. 1. A method of administering a drug using an infusion-patch , the infusion-patch comprising a cannula , a base , an adhesive region in the base , a skin-access area within the base , a drug-reservoir , and a conduit within the skin-access area , the method comprising:attaching the base of the infusion-patch to a surface of a skin using the adhesive region;transferring an anesthetic substance from a first anesthetic-reservoir through the conduit to the skin-access area and to the surface of the skin;at least partially replenishing the anesthetic substance in the skin-access area without removing the infusion-patch from the surface of the skin; anddelivering the drug from the drug-reservoir to the cannula, the cannula not being in fluid communication with the conduit.2. The method of claim 1 , further comprising:attaching the first anesthetic-reservoir to the infusion-patch3. The method of claim 2 , wherein:the infusion-patch comprises a connector,the connector is in fluid connection with the cannula, andattaching the first anesthetic-reservoir to the infusion-patch ...

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Номер записи: 42
03-01-2019 дата публикации

Multi-modal stimulation for treating tremor

Номер: US20190001129A1
Автор: Erika Kristine Ross, John PADERI, Kathryn H. Rosenbluth, Samuel Richard Hamner, Scott Lee DELP, Tahel Altman, Vijaykumar Rajasekhar
Принадлежит: Cala Health Inc

A peripheral nerve stimulator to stimulate a peripheral nerve to treat essential tremor and other movement disorders, as well as overactive bladder, cardiac dysfunction and neurotransmitter dysfunction is provided. The peripheral nerve stimulator can be a noninvasive surface stimulator to provide multi-modal optimized therapy. Stimulation can be vibrational, electromechanical, thermal, radiant, electrical, magnetic, electromagnetic, light, mechanical, chemical, thermal, ultrasonic, radiofrequency (RF), acoustic, infrared, ultraviolet, x-ray, and/or microwave. Stimulation can be delivered using an open loop system and/or a closed loop system with feedback. Stimulation can be to one site or multiple sites.

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Номер записи: 43
03-01-2019 дата публикации

APPARATUS AND METHOD FOR AUTOMATED COMPENSATION OF TRANSCUTANEOUS ELECTRICAL NERVE STIMULATION FOR TEMPORAL FLUCTUATIONS SUCH AS CIRCADIAN RHYTHMS

Номер: US20190001130A9
Автор: Gozani Shai N., Kong Xuan
Принадлежит:

Apparatus for transcutaneous electrical nerve stimulation in a user, the apparatus comprising: stimulation means for electrically stimulating at least one nerve with at least one stimulation pulse; control means connected to the stimulation means for controlling at least one characteristic of the at least one stimulation pulse; and modulating means connected to the control means for modulating the at least one characteristic of the at least one stimulation pulse according to the time of day. 1. Apparatus for transcutaneous electrical nerve stimulation in a user , the apparatus comprising:stimulation means for electrically stimulating at least one nerve with at least one stimulation pulse;control means connected to said stimulation means for controlling at least one characteristic of said at least one stimulation pulse; andmodulating means connected to the control means for modulating said at least one characteristic of said at least one stimulation pulse according to the time of day.2. Apparatus according to wherein said at least one characteristic is the amplitude of said at least one stimulation pulse.3. Apparatus according to wherein said at least one characteristic is the width of said at least one stimulation pulse.4. Apparatus according to wherein said at least one characteristic is the total charge of said at least one stimulation pulse.5. Apparatus according to wherein said at least one characteristic is the frequency at which said stimulation pulses are generated.6. Apparatus according to wherein said at least one characteristic is the duration of the therapy session.7. Apparatus according to wherein said at least one characteristic is the time between two consecutive therapy sessions.8. Apparatus according to wherein said modulating means comprises a periodic function.9. Apparatus according to wherein said periodic function is a sinusoid with a 24-hour period.10. Apparatus according to wherein said periodic function a biphasic square wave with a 24-hour ...

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Номер записи: 44
03-01-2019 дата публикации

MONITORING AND STIMULATION MODULE

Номер: US20190001131A1
Автор: ZIV Amos
Принадлежит: ZIV HEALTHCARE LTD.

Disclosed herein are portable and integrated modules and devices for non-intrusive neuromodulation and monitoring of heart function, and methods of operation thereof. The modules and devices include a monitoring unit, an electrical stimulation inducing unit, and three electrodes, such that one of the electrodes is dual-function, being controllably utilized for neuromodulation or for monitoring of heart function. 1. A portable module for monitoring of one or more heart parameters , and non-intrusive electrical neuro-stimulation of one or more peripheral nerves , and of a subject , comprising:a monitoring electrode, mounted in/on a top surface of the portable module;a stimulation electrode and a dual-function electrode, mounted in/on a bottom surface of the portable module;a monitoring unit for monitoring electrical activity;a stimulation unit for inducing electrical signals; anda control unit;wherein each of said electrodes is at least partly exposed; a first mode, wherein said monitoring unit is functionally associated with said monitoring and dual-function electrodes; and', 'a second mode, wherein said stimulation unit is functionally associated with said stimulation and dual-function electrodes;, 'wherein said control unit is configured to enable controllably switching between at least two modes of operation of the portable modulewherein the module is configured to facilitate simultaneously establishing dermal contact between a target body part of the subject and said dual-function electrode and between an opposing body part to the target body part and said monitoring electrode, thereby allowing, in the first mode, to obtain heart parameters of the subject by monitoring electrical activity at said dual-function and monitoring electrodes; andwherein the module is further configured to facilitate establishing dermal contact between the target body part and both of said dual-function electrode and said stimulation electrode, thereby allowing, in the second mode, to ...

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Номер записи: 45
03-01-2019 дата публикации

TRANSCRANIAL ELECTRICAL STIMULATION DEVICE HAVING MULTIPURPOSE ELECTRODES

Номер: US20190001133A1
Автор: Friis-Olivarius Morten, Jørgensen Ian, Kristoffersen Nanna Jordahn, Madsen Simon, Onarheim Balder, Ring Mads
Принадлежит:

The present invention relates to an electrotherapy stimulation device having at least three fully programmable multipurpose electrodes in fixed positions and the use of such device for achieving various cognitive effects such as those involved in creative problem solving. The electrodes of the present invention are multipurpose electrodes designed so each electrode can selectively serve multiple functions such as, but not limited to, as anode, cathode or ground of a stimulation circuit. 1. A system for applying a weak electrical current to a human brain or nervous tissue , wherein the system comprises:a) at least three multipurpose electrodes applied in a fixed position on the head of a human subject, wherein each electrode is wired to interchangeably function as anodal stimulation, cathodal stimulation, deactivation, or ground, andb) a distribution unit configured to provide the anodal stimulation, cathodal stimulation, deactivation, or ground,wherein at least two of the multipurpose electrodes are disposed on the right hemisphere and at least one is disposed on the left hemisphere.223-. (canceled)24. The system according to further comprising a control unit having an interface configured to communicate with the distribution unit.25. The system according to claim 1 , wherein the control unit is configured to provide a predetermined signal to the distribution unit.26. The system according to claim 25 , wherein the predetermined signal comprises predetermined sequences.27. The system according to claim 1 , wherein the distribution unit is configured to provide a weak electrical current of less than 3 mA per electrode.28. The system according to claim 27 , wherein the weak electrical current provided per electrode has the same intensity.29. The system according to claim 27 , wherein the weak electrical current provided per electrode has a different intensity.30. The system according to claim 27 , wherein the distribution unit provides the weak electrical current per ...

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Номер записи: 46
01-01-2015 дата публикации

Remote activation of the midbrain by transcranial direct current stimulation of prefrontal cortex

Номер: US20150005568A1
Автор: Hidehiko Takahashi, Kyongsik Yun, Shinsuke Shimojo, Vikram Chib
Принадлежит: California Institute of Technology CalTech

A method and system of remotely stimulating the midbrain area is disclosed. Transcranial direct current stimulation is applied via a cathode attached to the right dorsolateral prefrontal cortex and an anode attached to the ventromedial prefrontal cortex. These regions are either directly connected or indirectly connected to the midbrain region. The stimulation allows non-invasive stimulation of neurons in the midbrain region to address brain disorders such as Parkinson's disease, schizophrenia, depression and addiction.

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Номер записи: 47
01-01-2015 дата публикации

DEVICE FOR TREATMENT OF A WOUND

Номер: US20150005690A1
Автор: Busted Tommy
Принадлежит:

The present invention concerns a device for treatment of a wound by attachment to the skin, comprising a set of electrodes arranged on a carrier member and connected to an electrical power source having a first and a second terminal which are connected to each of the electrodes, wherein the set of electrodes comprises two non-interconnected electrically conducting wires arranged in a pattern on said carrier member and that the electrically conducting wires are provided with an irregular surface structure. 1. A device for treatment of a wound by attachment to the skin , comprisinga set of electrodes arranged on a carrier member and connected to an electrical power source having a first and a second terminal which are connected to each of the electrodes,whereinthe set of electrodes comprises two non-interconnected electrically conducting wires arranged in a pattern on said carrier member and wherein the electrically conducting wires are provided with an irregular surface structure.2. A device according to claim 1 , wherein the conducting wires are made of a precious metal.3. A device according to claim 1 , wherein the conducting wires are between 0.15-0.40 mm in diameter.4. A device according to claim 1 , wherein the set of non-interconnected conducting wires are substantially parallelly arranged in a serpentine-like pattern.5. A device according to claim 1 , wherein the carrier member has a distal side and a proximal side claim 1 , and the set of conducting wires are adhesively attached in the pattern to the proximal side of the carrier member and with a cover sheet.6. A device according to claim 5 , wherein the conducting wires penetrate through the carrier member where the wires are connected on the distal side of the carrier member to a cable from the power supply.7. A device according to claim 5 , wherein at least one wire is connected to the cable via a resistor.8. A device according to claim 5 , wherein said connection between the wires and the cable is covered ...

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Номер записи: 48
01-01-2015 дата публикации

TRANSDERMAL ELECTRICAL STIMULATION DEVICES FOR MODIFYING OR INDUCING COGNITIVE STATE

Номер: US20150005841A1
Автор: CHARLESWORTH Jonathan, DEMERS Remi, GOLDWASSER Isy, GRADWOHL Raymond L., LAMB Philip, PAL Sumon K., Tyler William J., VOSS Christopher, Wetmore Daniel Z.
Принадлежит:

Portable transdermal electrical stimulation (TES) applicators for modifying a subject's cognitive state. In general, the portable applicators described are specifically configured and adapted to be lightweight and may be wearable, and to deliver a high-intensity TES able to evoke or enhance a predetermined cognitive effect. These TES applicators may include a pair of electrodes and a TES control module comprising a processor, a timer and a waveform generator. TES control module is adapted to deliver a biphasic electrical stimulation signal of 10 seconds or longer between the first and second electrodes having a frequency of 400 Hz or greater, a duty cycle of greater than 10 percent, an intensity of 3 mA or greater, with a DC offset. 1. A portable transdermal electrical stimulation (TES) applicator for modifying a subject's cognitive state , the device comprising:a body;a first electrode;a second electrode; anda TES control module at least partially within the body and comprising a processor, a timer and a waveform generator, wherein the TES control module is adapted to deliver a biphasic electrical stimulation signal of 10 seconds or longer between the first and second electrodes having a frequency of 400 Hz or greater, a duty cycle of greater than 10 percent, and an intensity of 3 mA or greater.2. The device of claim 1 , further comprising a wireless receiver coupled to the TES control module.3. The device of claim 1 , wherein the first electrode is on an outer surface of the body.4. The device of claim 1 , wherein the first electrode is coupled to the body by a cord.5. The device of claim 1 , wherein the second electrode is coupled to the body by a cord.6. The device of claim 1 , further comprising an adhesive to secure the body to the subject.7. The device of claim 1 , further comprising a power source.8. The device of claim 1 , further comprising a manual control on the body coupled to the control module.9. The device of claim 1 , further comprising a capacitive ...

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Номер записи: 49
01-01-2015 дата публикации

TRANSCUTANEOUS ELECTRICAL STIMULATION FOR TREATING NEUROLOGICAL DISORDERS

Номер: US20150005852A1
Автор: Baynham Tamara C., Hershey Bradley L.
Принадлежит:

A method for treating a disorder of a patient. The method comprises transcutaneously delivering electrical energy to a targeted tissue site at a frequency of at least 50 KHz, thereby treating the disorder. 1. A method for treating a disorder of a patient , the method comprising:transcutaneously delivering electrical energy to a targeted tissue site at a frequency of at least 50 KHz, thereby treating the disorder.2. The method of claim 1 , wherein the frequency is at least 100 KHz.3. The method of claim 1 , wherein the targeted tissue site is at least 2 cm beneath the skin of the patient.4. The method of claim 1 , wherein the targeted tissue site is not more than 4 cm beneath the skin of the patient.5. The method of claim 1 , wherein the delivered electrical energy comprises an electrical pulse train.6. The method of claim 1 , wherein the delivered electrical energy reduces an impedance of the skin of the patient.7. The method of claim 1 , wherein the disorder is at least one of asthma claim 1 , skin cancer claim 1 , alopecia claim 1 , irritable bowel syndrome claim 1 , inflammatory bowel disease claim 1 , diabetes claim 1 , multiple sclerosis claim 1 , amyotrophic lateral sclerosis (ALS) claim 1 , high cholesterol claim 1 , overactive bladder claim 1 , migraine claim 1 , headache claim 1 , fibromyalgia claim 1 , complex region pain syndrome (I and II) claim 1 , angina claim 1 , arthritis claim 1 , leprosy and chronic pain.8. The method of claim 1 , further comprising affixing a patch electrode to the skin of the patient claim 1 , wherein the electrical energy is delivered by the patch electrode. The present application claims the benefit under 35 U.S.C. §119 to U.S. Provisional Patent Application No. 61/841,199, filed Jun. 28, 2013. The foregoing application is hereby incorporated by reference into the present application in its entirety.The present disclosure relates to systems and methods for transcutaneously treating neurological disorders in patients. ...

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Номер записи: 50
20-01-2022 дата публикации

SYSTEMS AND METHODS FOR TREATMENT OF PAIN FOLLOWING AMPUTATION AND SURGICAL TISSUE REMOVAL

Номер: US20220016421A1
Автор: Boggs, Crosby Nathan D., II JOSEPH W., Wongsarnpigoon Amorn
Принадлежит:

Paind felt in a given region of the body can be treated by stimulating a peripheral nerve at a therapeutically effective distance from the region where pain is felt to generate a comfortable sensation (i.e., paresthesia) overlapping the regions of pain. Systems and methods to reduce pain in a painful region following surgical amputation of an extremity or limb may include stimulating a peripheral nerve innervating the painful region with an electrode inserted into tissue and spaced from the peripheral nerve. This method may be used to help alleviate postoperative pain in patients following amputation of an extremity or limb. 1. A method to alleviate pain following an amputation surgery , the method comprising:inserting a coiled wire lead with at least one electrode percutaneously into a body within a therapeutically effective distance from at least one nerve to be transected; andapplying electrical stimulation through the at least one electrode to the nerve to be transected, thereby activating nerve fibers that innervate the region of pain expected from the amputation surgery in advance of the amputation surgery and causing an area of tingling sensations in the body, said area of tingling sensations being compared with an area affected by the at least one nerve innervating the region of pain expected from the amputation surgery.2. The method of claim 1 , wherein the at least one electrode comprises a pair of electrodes formed on the lead claim 1 , wherein the pair of electrodes are spaced apart with an insulated portion of the lead positioned therebetween.3. The method of claim 1 , wherein the electrical stimulation is provided to the nerve to be transected after said nerve is transected during the amputation surgery.4. The method of claim 1 , wherein the electrical stimulation includes a first parameter selected from a group consisting of: frequency claim 1 , pulse duration claim 1 , amplitude claim 1 , duty cycle claim 1 , pattern of stimulus pulses claim 1 , ...

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Номер записи: 51
20-01-2022 дата публикации

Devices, Systems, And Methods For Auricular Vagus Nerve Stimulation

Номер: US20220016425A1
Автор: Urbin Michael A.
Принадлежит:

A method of acutely activating the noradrenergic systems in a subject can comprise applying one or more electrical pulses to an ear canal (e.g., the left ear canal) of the subject, wherein the one or more electrical pulses are sufficient to acutely activate the noradrenergic system of the subject. Apparatuses and systems for applying one or more electrical pulses to an ear canal are also disclosed. 1. An apparatus comprising:an elongate body having a longitudinal axis and a first end and a second end that are spaced along the longitudinal axis;a first electrode positioned at the first end of the elongate body, wherein the first electrode is configured to be received at least partially in an ear canal of an ear;a second electrode positioned between the first electrode and the second end of the elongate body;a first conductor in electrical communication with the first electrode;a second conductor in electrical communication with the second electrode; anda housing that receives a portion of the elongate body therein, wherein the housing has a central axis, wherein the elongate body is pivotable relative to the housing about the central axis, wherein the housing is configured to retain the elongate body in a plurality of positions that are offset from each other by at least an azimuthal angle offset,wherein the apparatus is configured to provide electrical stimulation through or between the first and second electrodes, andwherein the housing comprises a support element that is configured to support the apparatus on an outer ear portion of the ear to permit electrical stimulation of a nerve adjacent to or within the ear.2. The apparatus of claim 1 , wherein the housing defines a socket claim 1 , wherein the apparatus further comprises a ball having an outer surface that is pivotably received within the socket claim 1 , wherein the ball is fixedly coupled to the elongate body so that the ball and the socket cooperate to enable movement of the elongate body relative to the ...

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Номер записи: 52
20-01-2022 дата публикации

APPARATUS AND METHOD FOR POSITIONING, IMPLANTING AND USING A STIMULATION LEAD

Номер: US20220016432A1
Автор: Boggs Joseph W., deBock Matthew G., McGee Meredith J., Sell Devin, STROTHER ROBERT B., Wongsarnpigoon Amorn
Принадлежит:

An introducing device for locating a tissue region and deploying an electrode is shown and described. The introducing device may include an outer sheath. An inner sheath may be disposed within the outer sheath. The inner sheath may be configured to engage an implantable electrode. In an example, the inner sheath may comprise a stimulation probe having an uninsulated portion at or near a distal end of the delivery sheath. The outer sheath may be coupled to a power source or stimulation signal generating circuitry at a proximal end. A clinician may control application of the stimulation signal to a tissue region via the outer sheath. 1. A system for testing , positioning , introducing and deploying a lead for percutaneous peripheral nerve stimulation , the system comprising:a delivery sheath having a distal opening and comprising a stimulation probe and an outer sheath having a distal opening;an inner deployment mechanism, selectively carried within the outer sheath, including an inner sheath and an open-coiled helical stimulation lead having a conductive distal anchor and an integrated electrode; andwherein the stimulation probe delivers test stimulation without deploying the distal anchor; and wherein the conductive distal anchor is released out of the delivery sheath when the inner deployment mechanism and outer sheath are moved in to a releasing position and subsequently retracted in concert.2. The system according to claim 1 , wherein the delivery sheath includes at least one bevel.3. The system according to claim 2 , wherein the distal opening includes a fully rounded edge to prevent sharp contact with any portion of the stimulation lead coming into contact with the rounded edge.4. The system according to claim 2 , wherein the distal opening includes an ovally rounded edge with a variable radius.5. The system according to claim 1 , wherein at least a portion of an outer surface of the delivery sheath is coated claim 1 , textured claim 1 , or marked to increase ...

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Номер записи: 53
12-01-2017 дата публикации

ELECTRICAL AND MAGNETIC STIMULATORS USED TO TREAT MIGRAINE/SINUS HEADACHE, RHINITIS, SINUSITIS, RHINOSINUSITIS, AND COMORBID DISORDERS

Номер: US20170007820A9
Автор: Errico Joseph P., Raffle John T., Simon Bruce J.
Принадлежит: ElectroCore, LLC

Transcutaneous electrical nerve stimulation devices and magnetic stimulation devices are disclosed, along with methods of treating medical disorders using energy that is delivered noninvasively by such devices. The disorders comprise migraine and other primary headaches such as cluster headaches, including nasal or paranasal sinus symptoms that resemble an immune-mediated response (“sinus” headaches). The devices and methods may also be used to treat rhinitis, sinusitis, or rhinosinusitis, irrespective of whether those disorders are co-morbid with a headache. They may also be used to treat other disorders that may be co-morbid with migraine or cluster headaches, such as anxiety disorders. In preferred embodiments of the disclosed methods, one or both of the patient's vagus nerves are stimulated non-invasively. In other embodiments, parts of the sympathetic nervous system and/or the adrenal glands are stimulated. 1. A device for treating rhinitis or sinusitis or rhinosinusitis in a patient comprising:a housing having an electrically permeable contact surface for contacting an outer skin surface of a patient; andan energy source within the housing configured to generate an electric field sufficient to transmit an electric current through the outer skin surface of the patient to a vagus nerve of the patient, wherein the electric current is sufficient to at least partially relieve a symptom selected from a group of symptoms comprising nasal or paranasal sinus congestion, nasal or paranasal sinus stuffiness, nasal or paranasal sinus obstruction, nasal or paranasal sinus inflammation, nasal or paranasal sinus edema, nasal or paranasal sinus vein dilation or engorgement, nasal or paranasal sinus vein hyper-permeability, rhinorrhea, facial pain or pressure, mucus discharge, nasal or paranasal sinus itching, sneezing, conjunctivitis, lacrimation, and eye redness.2. The device of wherein the energy source comprises a signal generator and one or more electrodes coupled to the ...

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Номер записи: 54
12-01-2017 дата публикации

ELECTROTHERAPY CABLE

Номер: US20170007822A1
Автор: HSU Chin-Chuan, YU Fu-Hao
Принадлежит:

An electrotherapy cable is installed with plural conductive patches and is constituted by a plug terminal, a cable line, an LED element and a conductive connector. Accordingly, the connection state of an electrotherapy machine can be known through the display state of the LED element, so as to facilitate identifying the usage state of the electrotherapy machine. 1. An electrotherapy cable which should be installed with plural conductive patches , the electrotherapy cable comprising:a plug terminal, which is provided with plural electrodes, the electrodes including a first electrode, a second electrode, a third electrode and a fourth electrode; anda cable line, an interior of which is provided with plural conductive wires connecting respectively with each electrode electrically, with the conductive wires connecting the first electrode and the third electrode being connected respectively with an LED (Light Emitting Diode) element and an electrotherapy intensity regulator electrically, the conductive wires connecting the second electrode and the fourth electrode being connected with a conductive connector electrically, and each conductive connector being connected electrically with the conductive patch.2. The electrotherapy cable according to claim 1 , wherein the plug terminal is provided with a first blanket material for installing the LED element.3. The electrotherapy cable according to claim 1 , wherein each conductive connector is provided with a second blanket material for installing the LED element.4. The electrotherapy cable according to claim 3 , wherein the conductive connector is provided with a connection portion to be engaged with the conductive patch.5. The electrotherapy cable according to claim 4 , wherein the connection portion is a plug connector or a fastener.6. The electrotherapy cable according to claim 5 , wherein the second blanket material is a translucent material or a non-translucent material.7. The electrotherapy cable according to claim 2 , ...

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Номер записи: 55
12-01-2017 дата публикации

Method and means to improve the effects of electrical cell and neuron stimulation with random stimulation in both location and time

Номер: US20170007828A1
Автор: Monteiro Sergio Lara Pereira
Принадлежит:

An electric stimulator for brain, heart, skin and internal organs in animals and plants where the electrodes are distributed on a supporting structure. The supporting structure may be adapted for brain, heart, skin or other internal organs, as for DBS, heart pacemaker, TENS, etc. The invention discloses a plurality of electrodes at the surface of the supporting structure, from which electrically stimulating currents can be injected into the organism. Turning off an electrode while turning on another electrode has the effect of moving the stimulation within the body of the organism from one point to another point, with the same effect but with less spent energy than physically moving the whole electrode support. We call this electrode shifting. Rotational and translational electrode shifting are possible. The invention also discloses random changes of the electrode shifting, and random changes of the stimulation time and of the stimulation duration. 1. A method of adjusting the location of an electrical stimulation caused by an electrical stimulator configured to be implanted in an animal comprising:providing a supporting structure configured to be attached to the animal;providing an electrode supporting structure with a proximal extremity, a distal extremity, a surface and an inner volume;providing a plurality of pads or electrodes at the surface of the electrode supporting structure;providing one or more electronic controlling unit which is configured to change the state of some of the electrodes from on to off and/or from off to on at different times or to leave the state of some of the electrodes unchanged,providing electrically connecting means connecting the electrodes at the surface of the electrode supporting structure to the one or more electronic controlling unit wherein,{'b': 1', '2', '1', '1', '3', '1', '3, 'the one or more electronic controlling unit is configured for providing a change in the electrodes that are turned on providing electrical ...

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Номер записи: 56
12-01-2017 дата публикации

SMART PORTABLE ELECTROTHERAPY MACHINE

Номер: US20170007830A1
Автор: HSU Chin-Chuan, YU Fu-Hao
Принадлежит:

The present invention is constituted by a body, an electric accumulator, an electric connecting wire, an electric quantity display module and an electric current control module. The electric accumulator is connected with the connector, an end of the electric connecting wire is provided with a butting connector which is connected electrically with the connector, and the other end of the electric connecting wire is provided with an electric current transmission element which is installed with a conductive patch. The electric quantity display module is connected electrically with the electric accumulator and the electric current control module is connected with the electric accumulator, so as to control the magnitude and intensity of electric current output in the electric accumulator, and update the electrotherapy mode wirelessly. 1. A smart portable electrotherapy machine , comprising:a body, having a holding space and an installing opening connecting the holding space, wherein a surface of the body is provided with a display area and a control area;an electric accumulator, which is installed in the holding space and connected electrically with a connector mounted at the installing opening;an electric connecting wire, an end of which is provided with a butting connector connecting electrically the connector, and the other end of which is provided with an electric current transmission element;an electric quantity display module, which is installed at the body, disposed in the display area and connected electrically with the electric accumulator;an electric current control module, which is installed at the body, disposed in the control area and connected with the electric accumulator, with the electric current control module including a control element, a circuit board connecting the control element, a processor installed on the circuit board, a power amplifier connecting the processor, a transformer connecting the power amplifier, the circuit board being provided with ...

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Номер записи: 57
14-01-2016 дата публикации

WIRELESS ELECTRICAL STIMULATION SYSTEM

Номер: US20160008597A1
Автор: CHEN Eric Ye
Принадлежит:

A system and method are provided for a wireless electrical stimulation. The system generally includes at least two electrical stimulation units. Each electrical stimulation unit includes electrodes connected to the unit. The system also includes a transmitter for remotely, wirelessly controlling each of the electrical stimulation units to selectively apply a time-varying electric potential to the electrodes to provide an electrical stimulation to tissue in electrical contact with the electrodes. 1. An electrical stimulation system for providing electrical stimulation to a subject's body , the system comprising:a wireless controller;an electrical stimulation unit generating electrical stimulation signals, responsive to the wireless controller;at least two electrodes adapted to be disposed in electrical contact with the subject's body spaced apart from the electrical stimulation unit and from each other; anda cable electrically connecting the electrical stimulation unit to the at least two electrodes to apply electrical stimulation signals from the electrical stimulation unit to the electrodes positioned remotely from the electrical stimulation unit.2. The system according to claim 1 , further comprising a substrate adapted to be applied to a body surface claim 1 , wherein the at least two electrodes are carried on the substrate.3. The system according to claim 2 , wherein the substrate is an article of clothing to be worn by the subject.4. The system according to claim 3 , wherein the article of clothing is a sock.5. The system according to claim 1 , wherein the cable is a Y-cable comprising a stem and two branches claim 1 , with a plug disposed on the end of the stem claim 1 , and a connector disposed on each of the branches claim 1 , the plug being configured to couple with a socket on the electrical stimulation unit and each of the connectors being configured for attaching to claim 1 , and electrically connecting to an electrode.6. The system according to claim 5 ...

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Номер записи: 58
14-01-2016 дата публикации

Wireless electrical stimulation system

Номер: US20160008609A1
Автор: Eric Ye Chen
Принадлежит: Individual

A system and method are provided for a wireless electrical stimulation. The system generally includes at least two electrical stimulation units. Each electrical stimulation unit includes electrodes connected to the unit. The system also includes a transmitter for remotely, wirelessly controlling each of the electrical stimulation units to selectively apply a time-varying electric potential to the electrodes to provide an electrical stimulation to tissue in electrical contact with the electrodes.

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Номер записи: 59
11-01-2018 дата публикации

ELECTRODE SENSOR KIT, ELECTRODE ASSEMBLY, AND TOPICAL PREPARATION FOR ESTABLISHING ELECTRICAL CONTACT WITH SKIN, USE THEREOF, AND METHOD OF ELECTRO-IMPEDANCE TOMOGRAPHY (EIT) IMAGING USING THESE

Номер: US20180008165A1
Автор: Bohm Stephan, Brunner Josef X.
Принадлежит:

An electrode sensor kit for establishing electrical contact with skin comprises at least one contact element and a preparation comprising a mixture of water and at least one lipid for enhancing electrical contact properties between said contact element and the skin, wherein said mixture forms an emulsion, in particular a water-in-oil or an oil-in-water emulsion, having a conductivity of less than 3 mS/cm. An electrode assembly for electrical impedance tomography which comprises said kit is characterized in that (a) said at least one contact element forms an electrode or sensor plate, and (b) said at least one contact element comprises a layer of said preparation. 133-. (canceled)34. A method of using an electrode sensor for performing biosignal measurements , comprisingapplying at least one contact element connectable to an analytical instrument and a preparation to skin of a test person, the preparation comprising a mixture of water and at least one lipid forming an emulsion having a conductivity of less than 1 mS/cm for enhancing electrical contact properties between the at least one contact element and the skin of the test person, the preparation interposed between the skin of the test person and the at least one contact element.35. The method of claim 34 , further comprising lining up in succession a plurality of contact elements with each contact element spaced apart a distance of 0.5 cm to 10 cm from an adjacent contact element.36. The method of claim 34 , further comprising performing biosignal measurements selected from the group consisting of an EIT-measurement claim 34 , a heart-rate-measurement or an ECG-measurement.37. The method of claim 34 , further comprising forming the mixture into an oil-in-water or water-in-oil emulsion.38. The method of claim 34 , further comprising selecting the preparation with at least one additive selected from a group of functional additives consisting of hyaluronic acid or salt claim 34 , hygroscopic substances claim 34 , ...

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Номер записи: 60
14-01-2021 дата публикации

COMMUNICATION DEVICES, METHODS, AND SYSTEMS

Номер: US20210007668A1
Автор: Leaper Matthew Robert
Принадлежит: DATAFEEL, LLC

Numerous aspects of communication devices, methods, and systems are described in this application. One aspect is a communication device comprising: a body comprising a distal surface compatible with skin; a tissue interface on the distal surface, the tissue interface comprising a plurality of energy generators, each energy generator being operable to output a plurality of energies in a signal direction toward the skin; and a processing unit configured to communicate with nerves associated with the skin by receiving input data, and causing the plurality of energy generators to output an energy signal in the signal direction with one or more energies of the plurality of energies. 1. A communication device comprising:a body comprising a distal surface compatible with skin;a tissue interface on the distal surface, the tissue interface comprising a plurality of energy generators, each energy generator being operable to output a plurality of different energy types in a signal direction toward the skin;an attachment element configured to maintain the tissue interface against the skin; anda processing unit configured to communicate with nerves associated with the skin by receiving input data from a data source and causing the plurality of energy generators to output an energy signal in the signal direction with one or more energy types of the plurality of different energy types.2. The device of claim 1 , wherein the body comprises one or more of:a flexible material;an insulating material; andan impact absorbing material.3. (canceled)4. The device of claim 1 , wherein the body is configured to promote flows of the one or more energy types of the plurality of different energy types in the signal direction claim 1 , and limit flows of the one or more energy types of the plurality of different energy types in directions between the plurality of energy generators.5. (canceled)6. The device of claim 1 , wherein the body is configured to direct or focus the one or more energy ...

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Номер записи: 61
27-01-2022 дата публикации

Transcranial alternating current dynamic frequency stimulation (tacs) system and method for alzheimers and dementia

Номер: US20220023629A1
Автор: John Patrick Claude
Принадлежит: Nexalin Technology Inc

Transcranial electrostimulation systems and methods are contemplated in which a high current level, charge balanced alternating current electrical signal is generated for delivery to the occipital region of a patient's brain. By stimulating the brain with a charged balanced stimulation current with a stimulation current envelope defining one or more series of pulses at particular frequencies and durations designed to evoke metabolic response in the neurons, significant improvements in efficacy and reductions in patient discomfort may be achieved relative to earlier methods of transcranial electrical stimulation, especially those in which result in a resultant rectified direct current component being administered to the patient. Further advantages, especially in promoting neural entrainment, may be realized as well via utilizing multiple series of pulses at different frequencies, and via the dynamic adjustment of the stimulation waveform via incorporation of feedback signals in order to maintain charge balance in real-time.

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Номер записи: 62
14-01-2021 дата публикации

NEUROMODULATION DEVICE AND METHOD FOR USE

Номер: US20210008368A1
Автор: IZVORSKI Alexander B., MCCULLOUGH Kevin, RAHIMI Shaun
Принадлежит: Thimble Bioelectronics, Inc. d/b/a Enso

Neuromodulation devices and methods of their use are described in which a therapeutic device is configured to generate a treatment for treating pain such as the reduction of the symptoms of chronic and acute pain as well as for treating other conditions. The neuromodulation device generates an output electrical signal in the form of pulses with a fast rise-time spike waveform followed by a longer-duration, lower amplitude primary phase waveform. The output signal includes a broad range of frequency components, with time constants tuned so as to interact with specific cell membrane or cellular components. The output signal may be conducted to the patient via electrodes. The pulses are triggered at variable intervals which prevent habituation. 148.-. (canceled)49. A method of neuromodulation treatment , comprising:transmitting a spike of at least one pulse waveform through one or more electrodes which are positioned in proximity to a tissue region of interest, the spike having a first amplitude of up to 100 V and a first duration time of up to 5 μs; andtransmitting a primary phase of the at least one pulse waveform following the spike through the one or more electrodes, the primary phase having a second amplitude and a second duration time, wherein the first amplitude is greater than the second amplitude and the first duration time is less than the second duration time such that the spike has an intensity which is greater than an average intensity of the primary phase.50. The method of wherein transmitting a spike comprises transmitting an electric field such that a conformational change is produced in cellular components of the tissue region of interest.51. The method of wherein transmitting a spike comprises transmitting a total energy per pulse of 55 μL.52. The method of wherein transmitting a spike comprises transmitting the spike with the first amplitude of between 80-100 V with the first duration time of between 1-5 μs.53. The method of further comprising ...

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Номер записи: 63
14-01-2021 дата публикации

SYSTEMS AND METHOD FOR DELIVERING PULSED ELECTRIC CURRENT TO LIVING TISSUE

Номер: US20210008369A1
Автор: Crosson John
Принадлежит:

A patient treatment unit for delivering non-invasive pulsed energy to living tissue with a probe stimulus generator circuit configured to output, as a treatment signal, a sequence of DC electrical pulses at a controlled pulse frequency of about 20 kHz and having a pulse voltage defined by a variable supply voltage of the probe stimulus generator circuit. The unit includes primary and secondary probes for contacting a body, an intensity adjustment circuit configured to control the variable supply voltage, and an electronic timer display configured to display an elapsed time in decimal numbers in minute and second format. An electrical current of the pulses is in a range of 0.1-2 mA while the probes are contacting the body. An operating output voltage across the probes while conducting the treatment signal does not exceed a maximum operating output voltage of 165 VDC while the probes are contacting the body. 1. A patient treatment unit comprising:a probe stimulus generator circuit that, while in active operation, generates a treatment signal including a pulse train of direct current (DC) pulses having a pulse frequency of about 20 kiloHertz (kHz), a pulse current from 0.1 milliAmperes (mA) to 8.9 mA for a defined range of load impedance, and a pulse voltage dependent on a variable supply voltage supplied to the probe stimulus generator circuit, the variable supply voltage providing a maximum pulse voltage of about 165 Volts of DC (VDC);a pair of electrically conducting probes coupled to the probe stimulus generator circuit for conducting the treatment signal through a body of a human or animal patient, as the load impedance, via non-invasive contact with skin of the patient;a mode control circuit configured to activate and deactivate a treatment mode of the patient treatment unit in response to operator input, wherein the treatment mode is characterized by the active operation of the probe stimulus generator circuit;an intensity adjustment circuit configured to ...

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Номер записи: 64
10-01-2019 дата публикации

VENOUS ELECTRICAL STIMULATION APPARATUS AND METHODS AND USES THEREOF

Номер: US20190009088A1
Автор: Phillips David Bruce
Принадлежит:

An electrical venous stimulation apparatus comprising an electrical signal generator, the signal generator configured to generate a specified electrical output signal. The apparatus also includes a plurality of electrodes in electrical communication with the signal generator and configured to be placed in electrical communication with a subject. The electrical output signal sent to the subject includes an output voltage, electrical current, and waveform that changes with time in a preprogrammed repeating cycle. The output voltage, electrical current, and waveform are configured to elicit a physiological response that stimulates a plurality of peripheral nerves in the subject, activates a venous muscle pump mechanism in one or more limbs of the subject, and non-invasively alter the physiology of target vein(s), wherein the target vein(s) is caused to distend from under the surface of the subject's skin. 1. An electrical venous stimulation apparatus for causing a target vein in a subject to enlarge and fill with blood under a surface of the subject's skin to enhance identification of suitable veins for cannulation , the electrical venous stimulation apparatus comprising:a power supply;a signal generator powered by the power supply, the signal generator configured to generate an electrical output signal;multiple electrodes in electrical communication with the signal generator and configured to be placed in electrical communication with the subject at different locations; and a first phase in which a positive polarity pulse above a baseline voltage is delivered;', 'a second phase in which a negative polarity pulse below a baseline voltage is delivered; and', 'a third phase in which no voltage is delivered for a time period prior to a next sequence of stimulation., "wherein the electrical output signal includes an output voltage, electrical current, and a waveform that changes with time in a preprogrammed repeating cycle, the output voltage, electrical current, and ...

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Номер записи: 65
09-01-2020 дата публикации

ELECTRICAL STIMULATOR FOR NEUROMUSCULAR STIMULATION

Номер: US20200009379A1
Автор: BIASIUCCI Andrea, MAESANI Andrea
Принадлежит:

The invention concerns an arrangement comprising an electrical stimulator (), a programming system () for assisting a user in programming it for performing a determined body movement by neuromuscular stimulation; and an input device () operable by the user. The programming system is configured to: decompose the neuromuscular movement into distinct actions (), select one of them, and configuring the electrical stimulator with the electrical stimulation parameters associated with the selected action. The programming system is further configured to select one electrical stimulation parameter among the electrical stimulation parameters associated with the selected distinct action, and, in a cycle performed while the electrical stimulator is connected to the user's body: to receive a value of the selected electrical stimulation parameter through the input device (); and to configure the electrical stimulator () with the received value of the selected electrical stimulation parameter. 2. The arrangement according to claim 1 , wherein said input device is arranged to provide a series of successive claim 1 , distinct values at a frequency bigger than 1 Hz claim 1 , preferably bigger than 10 Hz claim 1 , in response of a manipulation of the user.3. The arrangement according to claim 1 , wherein said electrical stimulation parameters define waveform claim 1 , amplitude claim 1 , impulse width and/or impulse frequency of electrical stimulation impulses generated in each of said chronological phases.4. The arrangement according to claim 1 , wherein electrical impulses generated in each chronological phase (pi) comprise one or a plurality of distinct trains of electrical stimulation impulses claim 1 , each train of electrical stimulation impulses being of a series of successive claim 1 , identical claim 1 , equally spaced claim 1 , electrical stimulation impulses.5. The arrangement according to claim 4 , wherein the programming system is arranged claim 4 , in said cycle claim 4 ...

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Номер записи: 66
08-01-2015 дата публикации

NONINVASIVE DELIVERY AND CONTROL OF STIMULATION SIGNALS

Номер: US20150012066A1
Автор: Underwood Wendell Martin
Принадлежит:

System and method for the non-invasive, wireless generation, delivery, and control of electrostimulation signals. The system contains a circuit board with a plurality of components protected by a silicone housing disposed in overlying relation to form a hollow interior therein. Collectively, this is one electrode. A plurality of electrodes are attached to an individual's body via leads on the underside of the electrodes. The electrodes are structured and adapted to transmit an electrical impulse into the individual's body, thereby performing a treatment (e.g., for pain relief). An electronic device can be used to activate or deactivate each electrode, along with control the length and strength of impulses, depending on the protocol used for the individual's treatment. Each impulse is made up of a plurality of bursts, and each burst is made up of a plurality of pulses, which are higher voltage signals transmitted from the circuit board through the leads. 1. A wireless electrostimulation system for generating and controlling stimulation signals delivered to the skin of an individual , comprising:at least one electrode including a housing having a contact portion and a non-contact portion forming a closed hollow interior therein, said contact portion being substantially planar and having an inner surface and an outer surface;a circuit board disposed on said inner surface of said contact portion, said circuit board having a battery and a plurality of components that receive an incoming electrical signal containing data and transmit an outgoing electrical signal in the form of an electrical impulse on said skin of said individual;said plurality of components including a controller component that manages operation of said plurality of components;said plurality of components further including a stimulator component that generates a high voltage charge that is delivered as said electrical impulses;said electrical impulses formed of a plurality of bursts, each of said ...

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Номер записи: 67
08-01-2015 дата публикации

NEUROSTIMULATION FOR TREATING PAIN, IMPROVING FUNCTION AND OTHER NERVOUS SYSTEM RELATED CONDITIONS

Номер: US20150012079A1
Автор: Chan Christopher, Goroszeniuk Teodor, Scibor-Rylski Mark
Принадлежит:

Various aspects of this disclosure relate to a patch for treating a patient for chronic pain and for cosmetic treatment. As consistent with one or more embodiments, neurostimulation is carried out via stimulating electrodes and one or more reference electrodes applied externally to a region of pain (e.g., by applying current between 0.2 and 60 mA to skin). The area to be treated is located either by a stimulating device, or by using at least one of the stimulating electrodes on the device itself to locate the pain prior to treatment. The electrodes are applied to the patient's skin as located using firm pressure while a stimulating pulse is applied as treatment. This action produces a remarkable and unexpected level of pain relief over a wide area. Aspects of the disclosure extend to a method for the treatment of chronic pain using the above-mentioned parameters and procedures. 1. An apparatus for treating a patient , the apparatus comprising:an insulating support;at least one rounded or substantially hemispherically-shaped or parabolically-shaped electrically-conducting stud projecting from one side of the insulating support, the at least one stud being configured and arranged with the insulating support to indent the patient's skin via the stud, in response to the insulating support being held against the patient's skin; andan electrical connector connected to the at least one stud and configured and arranged with the stud to connect the stud to a power source and to a signal generator of electrical stimulating signals.2. The apparatus of claim 1 , wherein the insulating support comprises a flexible strip claim 1 , band or patch claim 1 , and includes claim 1 , for each stud claim 1 , a stiff or rigid surrounding backing plate or washer configured and arranged to support the stud and having a diameter that is greater than the diameter of the stud and less than 3 times the diameter of the stud.3. The apparatus of in which the insulating support comprises an ...

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Номер записи: 68
03-02-2022 дата публикации

SLEEVE WITH CONFIGURABLE ELECTRODES FOR FUNCTIONAL ELECTRICAL STIMULATION AND/OR ELECTROMYOGRAPHY

Номер: US20220031245A1
Автор: Bresler Herbert S.
Принадлежит:

A device for functional electrical stimulation (FES), neuromuscular electrical stimulation (NMES), and/or electromyography (EMG) readout includes a sleeve sized and shaped to be worn on a human arm and comprising an inner sleeve and an outer sleeve. The inner sleeve has openings formed therein, and has an exposed side positioned to contact skin and an opposite backside facing the outer sleeve. Electrode strips each comprise a linear circuit board on which a row of electrodes is mounted. The electrode strips are detachably and selectively mountable to the inner sleeve in a plurality of different orientations. The electrode strips are mountable on the inner sleeve with the linear circuit boards disposed on the backside of the inner sleeve between the inner sleeve and the outer sleeve and the electrodes passing through the openings of the inner sleeve so as to be positioned to contact skin. 1. A device for use in performing functional electrical stimulation (FES) , in performing neuromuscular electrical stimulation (NMES) , in providing somatostimulation , and/or in receiving electromyography (EMG) signals , the device comprising:a sleeve sized and shaped to be worn on a human arm and comprising an inner sleeve and an outer sleeve wherein the inner sleeve has openings formed therein and has an exposed side positioned to contact skin of the human arm when the sleeve is worn on the human arm and an opposite backside facing the outer sleeve; andelectrode strips each comprising a linear circuit board on which a row of electrodes is mounted, the electrode strips being mounted on the inner sleeve with the linear circuit boards disposed on the backside of the inner sleeve between the inner sleeve and the outer sleeve and the electrodes passing through the openings of the inner sleeve so as to be positioned to contact skin of the human arm when the sleeve is worn on the human arm.2. The device of wherein:the electrodes comprise disk portions and connecting portions of narrower ...

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Номер записи: 69
03-02-2022 дата публикации

VIRTUAL PATCH ELECTRODES FOR ELECTRICAL MUSCLE STIMULATION AND TRANSCUTANEOUS ELECTRICAL NERVE STIMULATION

Номер: US20220032041A1
Автор: Branch Joshua R., Colachis Sam, Dunlap Collin F.
Принадлежит: BATTELLE MEMORIAL INSTITUTE

Disclosed is a muscle stimulation system, comprising a wearable garment including a plurality of electrodes, and a processor; wherein the processor is configured to define one or more regions of interest (ROI) for electrode activation via a subset of the plurality of electrodes, and provide electrical muscle stimulation, via the subset of the plurality of electrodes, to the ROI. 1. A system , comprising:a wearable garment including a plurality of electrodes; anda processor;wherein the processor is configured to define one or more regions of interest (ROI) for electrode activation via a subset of the plurality of electrodes, and to provide electrical muscle stimulation, via the subset of the plurality of electrodes, to the ROI.2. The system of further comprising a graphical user interface (GUI) configured to allow an operator to define one or more ROIs.3. The system of claim 2 , wherein the GUI is further configured to allow the operator to adjust the ROI.4. The system of claim 2 , wherein the GUI is further configured to allow the operator to select the subset of plurality of electrodes to activate and deactivate.5. The system of claim 2 , wherein the GUI is further configured to allow the operator to select which of the plurality of electrodes to designate as a cathode and which of the plurality of electrodes to designate as an anode.6. The system of claim 1 , wherein the processor is further configured to convert the ROI to a target pattern.7. The system of claim 6 , wherein the target pattern is a two-dimensional pattern.8. The system of claim 6 , wherein the target pattern is a three-dimensional pattern.9. The system of claim 1 , wherein the processor is further configured to scan at least one ROI to identify functional movements.10. The system of claim 9 , wherein the functional movements include a squat claim 9 , lunge claim 9 , hinge claim 9 , push claim 9 , pull claim 9 , or carry.11. The system of claim 9 , wherein the processor is further configured to ...

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Номер записи: 70
03-02-2022 дата публикации

PAIN RELIEF THERAPY

Номер: US20220032053A1
Автор: IRONI Alon
Принадлежит: THERANICA BIO-ELECTRONICS LTD.

Apparatus and methods are described including electrodes () configured to be placed upon a portion of a body of a subject, and a user interface device (). A computer processor () applies a neuromodulation treatment to the subject, by driving electrical pulses into the portion of the subject's body via the electrodes, and generates an output on the user interface device that indicates to the subject a physiological effect that the neuromodulation treatment has upon the subject's body. Other applications are also applied. 1. Apparatus comprising:electrodes configured to be placed upon a portion of a body of a subject;a user interface device; and ["apply a neuromodulation treatment to the subject, by driving electrical pulses into the portion of the subject's body via the electrodes; and", "generate an output on the user interface device that indicates to the subject a physiological effect that the neuromodulation treatment has upon the subject's body."], 'at least one computer processor configured to2. The apparatus according to claim 1 , wherein the computer processor is configured to reduce pain in a location of the subject's body that is at a distance of more than 25 cm from the portion of the subject's body into which the electrical pulses are driven claim 1 , by driving the electrical pulses into the portion of the subject's body.3. The apparatus according to or claim 1 , wherein the at least one computer processor is configured to reinforce an effectiveness of the neuromodulation treatment claim 1 , by generating the output.4. The apparatus according to any one of the preceding claims claim 1 , wherein the at least one computer processor is configured to generate the output by generating an audio output.5. The apparatus according to any one of the preceding claims claim 1 , wherein the at least one computer processor is configured to generate the output by generating a combined audio and graphical output.6. The apparatus according to any one of the preceding ...

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Номер записи: 71
03-02-2022 дата публикации

METHOD AND SYSTEM FOR IMPROVING PROVISION OF ELECTRICAL STIMULATION

Номер: US20220032054A1
Автор: Babcock Kevin G., Fineberg Alan, Lowenberg Rich, Razek Shawn, Wingeier Brett, Wolber Patrick
Принадлежит:

A method and system for providing stimulation to a user, the method including: transitioning a stimulation device from a baseline state to a first impedance monitoring state; during the first impedance monitoring state, guiding, an adjustment of a position of the stimulation device at a head region of the user to satisfy a first impedance criterion; upon satisfaction of the first impedance criterion, transitioning the stimulation device from the first impedance monitoring state to a stimulation regime that comprises a second monitoring state having a second criterion; upon detection of failure to satisfy the second criterion, transitioning the stimulation device from the stimulation regime to the first impedance monitoring state; and upon detecting that a third impedance criterion of the first impedance monitoring state is satisfied, transitioning the stimulation device from the first impedance monitoring state to the stimulation regime. 1upon activation of the electrical stimulation device, transitioning the electrical stimulation device from a baseline state to a first impedance monitoring state;during the first impedance monitoring state, determining a first impedance value of the electrical stimulation device;in an event that the first impedance value does not satisfy a first impedance criterion, guiding, with the controller, an adjustment of a position of the electrical stimulation device at the head region of the user until the first impedance criterion is satisfied, wherein guiding, with the controller, the adjustment of the position of the electrical stimulation device at the head region of the user comprises visually guiding the user, with a display of the controller, to adjust the position of a head-mountable portion of the electrical stimulation device; andupon satisfaction of the first impedance criterion, transitioning the electrical stimulation device from the first impedance monitoring state to a stimulation regime, wherein the stimulation regime ...

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Номер записи: 72
03-02-2022 дата публикации

CONDUCTIVE GEL RELEASE AND DISTRIBUTION DEVICES

Номер: US20220032078A1
Автор: Ballard Dale, Hulings Robert J., Quinnell Scott D., Seman Ronald A.
Принадлежит:

A gel deployment device for use with an electrotherapy system is provided. The device includes a plurality of gel reservoirs disposed on a substrate, each of the plurality of gel reservoirs containing conductive gel. Each of the gel reservoirs are positioned adjacent to at least one seal such that the seal restricts flow of the conductive gel. The seal can be configured to release the conductive gel from the gel reservoir in response to pressure being applied about a perimeter of the seal at, for example, multiple points about the perimeter or substantially equally about the perimeter of the seal. In an example, each gel reservoir can be shaped such that the gel reservoir partially or fully surrounds a seal. In another example, multiple gel reservoirs can be arranged in clusters such that the multiple gel reservoirs are positioned about a single seal. 128.-. (canceled)29. A wearable defibrillator electrotherapy delivery device to promote comfort of an ambulatory patient , the device comprising:a conductive surface configured to be in electrical contact with skin of the ambulatory patient and provide a therapeutic shock to the patient; andone or more ventilation holes disposed on the conductive surface, the one or more ventilation holes configured to provide air flow to the skin of the patient when the device is worn.30. The device of claim 29 , further comprising:a substrate mechanically coupled to the conductive surface, the substrate comprising at least one substrate ventilation hole configured to provide air flow to the skin of the patient when the device is worn; andone or more gel reservoirs disposed on the substrate and comprising a quantity of gel to be released to the skin of the patient prior to treatment of the patient.31. The device of claim 30 , wherein the at least one substrate ventilation hole is positioned to at least partially overlap one or more ventilation holes disposed on the conductive surface to provide air flow to the skin of the patient when ...

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Номер записи: 73
19-01-2017 дата публикации

DEVICES AND METHODS FOR CONTROLLING TREMOR

Номер: US20170014625A1
Автор: Altman Tahel, DELP Scott Lee, PADERI John, RAJASEKHAR Vijaykumar, Rosenbluth Kathryn H.
Принадлежит:

A peripheral nerve stimulator can be used to stimulate a peripheral nerve to treat essential tremor, Parkinson tremor, and other forms of tremor. The peripheral nerve stimulator can be either a noninvasive surface stimulator or an implanted stimulator. Stimulation can be electrical, mechanical, or chemical. Stimulation can be delivered using either an open loop system or a closed loop system with feedback. 1. A system for treating tremor in a patient , the device comprising: a decision unit,', 'a first peripheral nerve effector, comprising at least one stimulation electrode configured to be positioned to modulate an afferent nerve pathway, and', 'wherein the decision unit comprises a processor and a memory for storing instructions that, when executed by the processor, causes the device to:', "deliver an electrical stimulus to a first afferent nerve through the first peripheral nerve effector to reduce tremor in the patient's extremity;"], 'a wearable device, comprisinga communication device configured to communicate with and receive data from the wearable device, the communication device further configured to transmit the data to a cloud computing network or server for storage and/or data processing; anda computing device configured to be accessed by the patient's physician, the computing device in communication with the cloud computing network or server and further configured to retrieve and display the data from the cloud computing network or server.2. The system of claim 1 , wherein the first electrical stimulus has a frequency of at least 1000 Hz.3. The system of claim 1 , wherein the wearable device further comprises at least one biomechanical sensor configured to measure movement of the patient's extremity to characterize one or more features of the tremor claim 1 , the one or more features of the tremor selected from the group consisting of tremor frequency claim 1 , tremor period claim 1 , and tremor magnitude; ["measure the movement of the patient's ...

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Номер записи: 74
18-01-2018 дата публикации

System and method for ensuring airway patency when asleep

Номер: US20180015281A1
Автор: Kingman P. Strohl
Принадлежит: CASE WESTERN RESERVE UNIVERSITY

One aspect of the present disclosure relates to a system that provides an alternative to traditional treatments for sleep apnea. The system allows to apply an electrical stimulus through an electrode to stimulate an afferent nerve fiber while a patient is sleeping. The system also includes activating an endogenous central nervous system (CNS)-regulated reflex response to coordinate upper airway muscles based on the stimulation of the afferent nerve fiber. Based on the endogenous CNS-regulated reflex response, an airway patency in the sleeping patient can be regulated.

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Номер записи: 75
18-01-2018 дата публикации

System and method for relieving hypertension

Номер: US20180015283A1
Автор: Wen-Chieh Chang
Принадлежит: Taiwan Resonant Waves Research Corp

A system and method for relieving hypertension includes an energy wave generator set an energy wave's frequency control mode for controlling and generating energy waves with correspond energy densities in multiple energy wave generation periods to effect on a body with hypertension, so as to relieve hypertension by the specific energy wave.

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Номер записи: 76
18-01-2018 дата публикации

PATIENT THERAPY SYSTEMS AND METHODS

Номер: US20180015284A1
Автор: Butters Joshua, Coleman Struan, Domenico Calvin, Gieswein Edison, Kessler Marlina, Knox Lee, Paparella Jessica, Saar David
Принадлежит:

Some embodiments include a system with a sensor with electrodes including an active electrode and a receiving electrode that is in physical contact with skin of a patient forming an electrical circuit with control electronics of a controller that can measure an electrical parameter using an active electrode and a receiving electrode within a closed loop electrical muscle stimulation system. A sense electrical pulse can be applied to the tissue using the sensor, an electrical parameter measured from the tissue, and a stimulation pulse applied to the tissue based at least in part on the measured electrical parameter. The stimulation is adjustably controlled by the controller to maintain a constant power output to the tissue based on the electrical parameter. A good is coupled to a computer readable medium configured to store usage data, the usage data relating to the patient's use of the good. 1. A system comprising:at least one sensor comprising a plurality of electrodes including at least one active electrode and at least one receiving electrode, the at least one sensor configured and arranged to be in physical contact with skin of a patient forming an electrical circuit with control electronics of at least one controller, the electrical circuit configured and arranged to measure an electrical parameter using the at least one active electrode and at least one receiving electrode, and to form a closed loop electrical muscle stimulation system, wherein a stimulation current or voltage applied by the sensor onto the skin between the at least one active electrode and at least one receiving electrode is based on at least one program and at least one electrical parameter measured through the at least one active electrode and at least one receiving electrode,the at least one controller configured and arranged for (a) applying a sense electrical pulse to the tissue using the at least one sensor, (b) measuring the at least one electrical parameter from the tissue, (c) using ...

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Номер записи: 77
18-01-2018 дата публикации

APPARATUS AND METHOD FOR AUTOMATED COMPENSATION OF TRANSCUTANEOUS ELECTRICAL NERVE STIMULATION FOR TEMPORAL FLUCTUATIONS SUCH AS CIRCADIAN RHYTHMS

Номер: US20180015285A1
Автор: Gozani Shai N., Kong Xuan
Принадлежит:

Apparatus for transcutaneous electrical nerve stimulation in a user, the apparatus comprising: stimulation means for electrically stimulating at least one nerve with at least one stimulation pulse; control means connected to the stimulation means for controlling at least one characteristic of the at least one stimulation pulse; and modulating means connected to the control means for modulating the at least one characteristic of the at least one stimulation pulse according to the time of day. 1. Apparatus for transcutaneous electrical nerve stimulation in a user , the apparatus comprising:stimulation means for electrically stimulating at least one nerve with at least one stimulation pulse;control means connected to said stimulation means for controlling at least one characteristic of said at least one stimulation pulse; andmodulating means connected to the control means for modulating said at least one characteristic of said at least one stimulation pulse according to the time of day.2. Apparatus according to wherein said at least one characteristic is the amplitude of said at least one stimulation pulse.3. Apparatus according to wherein said at least one characteristic is the width of said at least one stimulation pulse.4. Apparatus according to wherein said at least one characteristic is the total charge of said at least one stimulation pulse.5. Apparatus according to wherein said at least one characteristic is the frequency at which said stimulation pulses are generated.6. Apparatus according to wherein said at least one characteristic is the duration of the therapy session.7. Apparatus according to wherein said at least one characteristic is the time between two consecutive therapy sessions.8. Apparatus according to wherein said modulating means comprises a periodic function.9. Apparatus according to wherein said periodic function is a sinusoid with a 24-hour period.10. Apparatus according to wherein said periodic function a biphasic square wave with a 24-hour ...

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Номер записи: 78
21-01-2016 дата публикации

Smart Patch For Wound Management

Номер: US20160015962A1
Автор: Jung Yei Hwan, Kumar Akshay, Sandock Sarah R., Shokoueinejad Maragheh Mehdi
Принадлежит:

A flexible patch is provided that is capable of emitting light in the UV, visible, and/or infrared electromagnetic spectrums. The patch contains a feedback process and system using one or more sensors and a controller on the patch to () accelerate the wound healing process by providing adaptable, controlled light exposure and electrical stimulation, () monitor the healing process for signs of infection () eliminate bacterial infections by sanitizing the infected site and () relaying the information wirelessly to a central location for storage and interpretation by a physician as well as by providing the ability to receive feedback and operating instructions from the physician from a remote location.

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Номер записи: 79
17-01-2019 дата публикации

EXTERNAL DEFIBRILLATION ELECTRODE CONDUCTIVE ELECTROLYTE DISPERSAL PAD

Номер: US20190015657A1
Автор: Bast Gerard A., Cano David A., Crutchfield Randolph E., II Jerome, Mesias Lisa Anne Harness, Norgaard Clark B., Porter Mark E., Sims, Timson Philip
Принадлежит:

An external defibrillator system may include processing circuitry; signal generation circuitry communicatively coupled to the processing circuitry; and a plurality of electrodes, each including an electrode body electrically coupled to the signal generation circuitry and configured to deliver an electrical pulse therapy to a patient; and an electrolyte dispersal pad that includes a substrate defining a plurality of wells, each defining an opening; an electrolyte material, e.g., fluid, disposed within at least a portion of the plurality of wells; and a conductive material disposed over at least a portion of the openings and configured to retain the electrolyte material within the plurality of wells, where the processing circuitry is configured control the signal generation circuitry to pass a current pulse through a portion of the conductive material to fuse the portion of the conductive material to release the electrolyte material from at least one of the wells. 1. An external defibrillator system , the system comprising:processing circuitry;signal generation circuitry communicatively coupled to the processing circuitry; and an electrode body electrically coupled to the signal generation circuitry and configured to deliver an electrical pulse therapy to a patient; and', a substrate defining a plurality of wells, each respective well defining an opening;', 'an electrolyte material disposed within the plurality of wells; and', 'a conductive material disposed over at least a portion of the plurality of openings and configured to retain the electrolyte material within the plurality of wells,, 'an electrolyte dispersal pad over the electrode body, the electrolyte dispersal pad comprising], 'a plurality of electrodes, each respective electrode comprising 'the processing circuitry is configured control the signal generation circuitry to pass a current pulse through a portion of the conductive material to fuse the portion of the conductive material to release the ...

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Номер записи: 80
15-01-2015 дата публикации

PROMOTING TRANSCRANIAL DIRECT CURRENT STIMULATION OR TRANSCRANIAL MAGNETIC STIMULATION USING TEMPERATURE-INDUCED SYNAPTIC MODULATION

Номер: US20150018667A1
Автор: HALLETT MARK, Radman Thomas C.
Принадлежит:

Disclosed herein are representative embodiments of methods, systems, and apparatus for enhancing or diminishing synaptic strength. Embodiments of the disclosed methods, systems, and apparatus can be used, for example, to complement the change in synaptic strength from transcranial direct current stimulation (“tDCS”) or transcranial magnetic stimulation (“TMS”) systems. One exemplary embodiment disclosed herein is a flexible housing having a top surface and a bottom surface. The flexible housing of this embodiment comprises a recessed cavity on the bottom surface that is configured to at least partially enclose an electrode of a transcranial direct current stimulator system. The flexible housing of this embodiment further comprises one or more apertures configured to provide access to the recessed cavity when the electrode is positioned within the recessed cavity. The flexible housing can further comprise one or more heating or cooling elements that can be selectively activated before, during, and/or after tDCS or TMS stimulation. 148-. (canceled)49. A method , comprising: decreasing a temperature of a region of the cranium of a subject from a base line temperature to a cooled temperature, the region of the cranium of the subject being adjacent to a target region of the cerebral cortex of the subject, and', 'sustaining the cooled temperature at the region on the cranium of the subject; and for a second period of time,', 'activating an electrical or magnetic stimulator positioned at or adjacent to the region of the cranium of the subject, thereby electrically or electromagnetically stimulating the target region of the cerebral cortex of the subject; and', 'sustaining the activation of the electrical or magnetic stimulator., 'for a first period of time,'}50. The method of claim 49 , wherein the first period of time ends before the second period of time begins.51. The method of claim 49 , wherein the first period of time and the second period of time at least partially ...

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Номер записи: 81
16-01-2020 дата публикации

Electrolyte Liner for Transcutaneous Stimulation Electrode

Номер: US20200016394A1
Автор: MINOGUE Conor
Принадлежит:

An electrolyte liner for use with an electrode for transcutaneous electrical stimulation, the liner comprising a flexible porous sheet of material containing a predetermined amount of liquid or gel electrolyte per unit area, said sheet being shaped to cover a skin facing surface of said electrode. 1. An electrolyte liner for use with an electrode for transcutaneous electrical stimulation , the liner comprising:a flexible porous sheet of material containing a predetermined amount of liquid or gel electrolyte per unit area, said sheet being shaped to cover a skin facing surface of said electrode.2. An electrolyte liner of claim 1 , wherein the sheet is relatively thin claim 1 , characterised by a dry grammage between 40 to 100 g/m.3. An electrolyte liner of claim 1 , wherein the sheet is relatively thin claim 1 , characterised by a thickness between 30 μm to 400 μm.4. An electrolyte liner of claim 3 , wherein the sheet is characterised by a thickness between 50 μm to 200 μm.5. An electrolyte liner of claim 1 , wherein the predetermined amount of liquid or gel electrolyte in the sheet per unit area is between 1 mg/cmand 5 mg/cm.6. An electrolyte liner of claim 5 , wherein the predetermined amount of liquid or gel electrolyte in the sheet per unit area is between 2 mg/cmand 4 mg/cm.7. An electrolyte liner of any preceding claim 1 , wherein the sheet has a bulk resistivity between 0.140 m and 1.20 m.8. An electrolyte liner of claim 1 , wherein the liner is made of textile or fabric claim 1 , selected from woven claim 1 , non-woven or knitted textiles or fabrics.9. (canceled)10. An electrolyte liner of claim 1 , wherein the electrolyte liner comprises a sleeve or manifold.11. An electrolyte liner of claim 10 , wherein the sleeve or manifold corresponds to a sleeve or manifold portion of a garment containing said electrode claim 10 , wherein said sleeve or manifold is configured to be positioned between the corresponding sleeve or manifold portion of the garment and a user ...

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Номер записи: 82
21-01-2021 дата публикации

TRANSCUTANEOUS ELECTRICAL MUSCLE STIMULATION DEVICE FOR THE TREATMENT OF PREMATURE EJACULATION OR ERECTILE DYSFUNCTION, AND METHODS OF USE THEREOF

Номер: US20210016078A1
Автор: GOLLAN Tal
Принадлежит: Virility Medical Ltd.

In one embodiment, the present invention provides a device, wherein the device comprises a skin patch, configured to attach to the skin surface of the perineum of a subject suffering from premature ejaculation, wherein the skin patch contains electrodes configured to deliver electrical impulses transcutaneously to the bulbcavernosus muscle of the subject, wherein the transcutaneously delivered electrical impulses are configured to treat premature ejaculation. 1. A device , comprising:a skin patch having a first surface and a second surface, wherein said first surface is configured to attach said skin patch to a skin surface of a subject, wherein the skin patch contains at least two electrodes positioned at a distance between each other suitable to deliver electrical impulses transcutaneously to one or more of the bulbospongiosus muscle, the bulbocavernosus muscle, the ischiocavernosus muscle, and to the neuromuscular junction of the nerves innervating the ischiocavernosus and bulbospongiosus muscles of the subject; a battery connected to said at least two electrodes;', 'an electronic circuitry including a controller electrically connected to said battery;, 'an electronic circuit housing integrated with said second surface of said skin patch, and comprisingwherein said electronic circuitry is configured to receive a radio frequency signal, and to deliver said electrical impulses from said battery to said at least two electrodes in response to said radio frequency signal.2. The device of claim 1 , wherein all of said device including said skin patch which includes said at least two electrodes and said electronic circuit housing claim 1 , is shaped and sized to be attached to to said skin surface of said subject.3. The device of claim 2 , wherein all of said device is shaped and sized to be attached to the skin surface of the subject.4. The device of claim 1 , wherein said device is configured to fit between and conform to each of the thigh-groin crease of a subject.5. ...

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Номер записи: 83
21-01-2021 дата публикации

ELECTRICAL STIMULATION SYSTEM AND METHODS FOR LIMB CONTROL

Номер: US20210016079A1
Автор: Ekelem Andrew, Goldfarb Michael
Принадлежит:

The present disclosure provides various systems and methods for assisting with lower limb movement. An exemplary system can include a plurality of wearable modules and a controller. Each of the plurality of wearable modules can include a stimulator and a sensor. The controller can be configured to detect a desired activity based on data from the sensors on the wearable modules. The controller can be further configured to cause the stimulator to provide electrical stimulation to assist with the desired activity. 1. A system for assisting lower limb movement , the system comprising: at least one stimulator including a pair of electrodes positioned adjacent to human tissue of a lower limb, the at least one stimulator configured to cause a plurality of action potentials at the human tissue; and', 'at least one inertial sensor configured to receive inertial data of the at least one wearable module; and, 'at least one wearable module including determine a desired activity and at least one trait of the desired activity based on the inertial data; and', 'apply at least one action potential from the plurality of action potentials to the human tissue, via the at least one stimulator, for a selected duration, based on the desired activity, the at least one trait, and the inertial data., 'a controller communicatively coupled to the at least one stimulator and the at least one inertial sensor, the controller configured to2. The system of claim 1 , wherein the desired activity includes clonus suppression claim 1 , and wherein applying the at least one action potential comprises stimulating a nerve that modulates the clonus reflex pathway.3. The system of claim 1 , wherein the at least one inertial sensor comprises two or more accelerometers.4. The system of claim 3 , wherein the desired activity includes cyclic motion assistance claim 3 , and wherein applying the at least one action potential comprises applying a synchronous pattern of action potentials to stimulate a cyclic ...

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Номер записи: 84
21-01-2021 дата публикации

ELECTRODE CONTACT MONITORING

Номер: US20210016080A1
Автор: MINOGUE Conor
Принадлежит:

A system for assessing the quality of electrical contact in transcutaneous electrical stimulation includes an array having at least three electrodes (A, B, C) and at least two electrode pairings (AB, BC) of the array have a common electrode (B). A controller controls flow of current pulses between different electrode pairings (AB, AC, BC) of the array. A measurement device measures at least one voltage across each of the at least two electrode pairings (AB, BC) of the array during a stimulation pulse in response to a constant current pulse. 1. A system for assessing quality of electrical contact in transcutaneous electrical stimulation , the system comprising:i. an array comprising at least two electrodes;ii. a controller for controlling flow of current pulses within electrode pairings of the array; andiii. a voltage measurement device for measuring at least one voltage sample between electrodes at at least one time point within a stimulation pulse;iv. a calculator for calculating a time dependent factor based on the voltage sample or samples; compare the calculated time dependent factor with a pre-determined acceptance limit;', 'characterise the quality of electrode contact as acceptable if the calculated time dependent factor is less than or equal to the pre-determined acceptance limit; and', 'characterise the quality of electrode contact as unacceptable if the calculated time dependent factor is greater than the predetermined acceptance limit., 'v. an assessor for assessing quality of electrode contact; the assessor configured to2. The system of claim 1 , wherein the voltage measurement device is configured to measure at least one voltage sample between electrodes at a plurality of time-points within the stimulation pulse.3. The system of claim 1 , wherein the time dependent factor is the difference between an initial voltage step and a voltage at a later time point in the stimulation pulse.4. The system of claim 1 , wherein the time dependent factor is the ...

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Номер записи: 85
21-01-2021 дата публикации

OCCLUSION THERAPY AND PELVIC STIMULATION SYSTEM

Номер: US20210016087A1
Автор: Allen Answorth, COLEMAN Struan H., Shahriari Kereshmeh
Принадлежит:

The system is directed to improving muscle strength using electrostimulation therapy and/or occlusion according to some embodiments. In some embodiments, the system is configured to use electrodes placed outside the body and/or on the surface of the skin to activate pelvic floor muscles to control urine flow from the bladder. In some embodiments, the system includes one or more fluid bladders configured to reduce blood flow to a targeted area while applying electrostimulation using one or more electrodes. In some embodiments, the occlusion system results in higher muscle growth and/or retraining results than conventional methods. 1. A garment system comprising:an occlusion system comprising one or more fluid bladders, andan electrostimulation system comprising one or more electrodes;wherein the occlusion system is configured to reduce the flow of blood to at least a portion of a user's body while the electrostimulation system simultaneously applies electrical stimulation to one or more muscles within an area of the reduced the flow of blood.2. The garment system of claim 1 ,wherein the at least one fluid bladder is placed on top of at least one of the plurality of electrodes.3. The garment system of claim 1 ,wherein the at least one fluid bladder is placed adjacent to at least one of the plurality of electrodes.4. The garment system of claim 1 ,wherein the electrostimulation system comprises at least one sensor comprising a plurality of electrodes including at least one active electrode and at least one receiving electrode, the at least one sensor configured and arranged to be in physical contact with skin of a patient forming an electrical circuit with control electronics of at least one controller, the electrical circuit configured and arranged to measure an electrical parameter using the at least one active electrode and at least one receiving electrode, and to form a closed loop electrical muscle stimulation system;5. The garment system of claim 4 ,wherein a ...

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Номер записи: 86
21-01-2021 дата публикации

METHODS FOR DELIVERING PULSED ELECTRIC CURRENT TO LIVING TISSUE

Номер: US20210016089A1
Автор: Crosson John
Принадлежит:

A patient treatment unit for delivering non-invasive pulsed energy to living tissue with a probe stimulus generator circuit configured to output, as a treatment signal, a sequence of DC electrical pulses at a controlled pulse frequency of about 20 kHz and having a pulse voltage defined by a variable supply voltage of the probe stimulus generator circuit. The unit includes primary and secondary probes for contacting a body, an intensity adjustment circuit configured to control the variable supply voltage, and an electronic timer display configured to display an elapsed time in decimal numbers in minute and second format. An electrical current of the pulses is in a range of 0.1-2 mA while the probes are contacting the body. An operating output voltage across the probes while conducting the treatment signal does not exceed a maximum operating output voltage of 165 VDC while the probes are contacting the body. 1. A method of treating pain or inflammation or a wound in a patient to reduce or treat the pain or inflammation or wound , comprising the steps of: placing a first conductor and a second conductor at first and second locations onto living tissue of a body of a human or animal in an area where pain or inflammation or wound is indicated, the first conductor having an electrically conductive tip, the first and second conductors being electrically coupled to the patient treatment unit having a first timer display configured to display a resettable timer,', 'applying firm pressure to at least the first conductor while the tip contacts the living tissue,', 'causing electrical energy to be delivered through the first and second conductors and into the tissue in the form of a treatment signal supplied by the patient treatment unit, the treatment signal including a pulse train of direct current (DC) pulses having a pulse frequency in a range between 18 and 22 kiloHertz (kHz), a pulse current from 0.1 milliAmperes (mA) to 6.0 mA, and a pulse voltage dependent on a variable ...

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Номер записи: 87
15-01-2015 дата публикации

STIMULATION DEVICE

Номер: US20150018925A1
Автор: HARTLEP Andreas, ZSCHAECK Thomas
Принадлежит:

A stimulation device for transcutaneous electric stimulation stimulus onto the surface of a section of the human ear comprises a holding element attached at or in the ear and at least two electrodes arranged in or at an electrode carrier, wherein the at least two electrodes are separated from another at the electrode carrier by an electrically isolating section. To obtain a good electrical conductibility of the electrodes at high ear comfort, the at least two electrodes are covered by a casing element, the casing element comprises at least two cover elements, wherein each of the at least two cover elements comprises a retaining region for an electrode; the material of the cover elements is electrically conductive or can be made electrically conductive; the casing element comprises at least one isolation section made of electrically isolating material; the isolating section connects at least two cover elements with another. 1. Stimulation device for the application of a transcutaneous electric stimulation stimulus onto the surface of a section of the human ear , which comprises a holding element which can be attached at or in the ear as well as at least two electrodes which are arranged in or at an electrode carrier , wherein the at least two electrodes are separated from another at the electrode carrier by an electrically isolating section ,whereinthe at least two electrodes are covered by a casing element, wherein the casing element comprises at least two cover elements, wherein each of the at least two cover elements comprises a retaining region for an electrode, wherein the material of the cover elements is electrically conductive or can be made electrically conductive, wherein the casing element comprises at least one isolation section made of electrically isolating material, wherein the isolating section connects at least two cover elements with another.2. Stimulation device according to claim 1 , characterized in that the at least two electrodes extend from ...

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Номер записи: 88
15-01-2015 дата публикации

STIMULATION DEVICE

Номер: US20150018926A1
Автор: FRENKEL Wolf Gerhard, HARTLEP Andreas, ZSCHAECK Thomas
Принадлежит:

A stimulation device for transcutaneous electric stimulation stimulus onto the surface of a section of the human ear comprises a holding element attached at or in the ear, at least two electrodes arranged in or at an electrode carrier. To obtain high contact quality of the electrodes with high wearing comfort, the holding element consists of one part designed as holding bow for placement between the surface of the head and the Pinna (P) of the device wearer, the other part designed as connection element between the holding bow and the electrode carrier; between the holding bow and the connection element a hinge joint is arranged such that use of the device allows swivel movement of the connection element relatively to the holding bow around an axis (S) parallel or under an angle (α) of less than 30° to the straight ahead viewing direction (G) of the device wearer. 2. Stimulation device according to claim 1 , characterized in that the hinge joint is pre-loaded by means of a spring element in a swivel direction.3. Stimulation device according to claim 2 , characterized in that means are arranged by which the pre-load of the spring element can be adjusted.4. Stimulation device according to claim 1 , characterized in that the electrode carrier is rigidly fixed at one end of the connection element claim 1 , wherein the fixation is preferably designed as releasable fixation.5. Stimulation device according to claim 4 , characterized in that the fixation of the electrode carrier at the connection element takes place via a form-fit connection claim 4 , especially by means of a dovetail groove claim 4 , which is machined into the electrode carrier or in the connection element and which cooperates with a congruent counterpart claim 4 , which is arranged at the connection element or at the electrode carrier.6. Stimulation device according to claim 1 , characterized in that the holding bow is designed sickle shaped and that the hinge joint is arranged at one of its ends.7. ...

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Номер записи: 89
15-01-2015 дата публикации

DEVICE FOR NEUROSTIMULATION

Номер: US20150018927A1
Автор: Warschewske Udo
Принадлежит: EBS TECHNOLOGIES GMBH

The invention relates to a device for neurostimulation, comprising a mask, eyeglasses or similar eye attachment covering the eye region of the subject, which is designed to be optically sealed from the surroundings and has a lighting surface directed to the eye side which is connected to a source emitting light in the visible spectral range or contains such a light source, and having means for fastening to the head of the subject. According to the invention, there is a base element, open on one side, which receives the respective lighting surface and light source on the inside thereof, wherein there are electrode receptacles or electrode support surfaces on the base element above and/or below the region covering the eye region, furthermore a flexible, replaceable cushion-like or mat-like flat element can be fastened on the base element, which flat element has openings that are complementary to the electrode receptacles or electrode support surfaces, wherein the flat element comes in contact with the forehead area of the eye region of the subject when the device is used and the electrodes are designed to be epicutaneous. 1. Device for neurostimulation via electrodes , comprising a mask , eyeglasses or other eye attachment covering an eye area of a subject which is configured to be optically sealed from the surroundings and has an illuminated surface which is directed to the eye side and is connected to a source emitting light in the visible spectral range or contains such a light source , the device being fixable to the head of the subject , and comprising:a base body, open on one side, which receives the respective illuminated surface and light source in its interior, wherein electrode receptacles or electrode support surfaces are provided on the base body above and/or below the region covering the eye area, anda flexible, exchangeable cushion-like or mat-like surface body fixable to the base body, the surface body having through openings that are complementary to ...

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Номер записи: 90
28-01-2016 дата публикации

ELECTRODE SYSTEM FOR ELECTRICAL STIMULATION

Номер: US20160022981A1
Автор: Bar-Or Tal, Davis Colin, Hammett Victoria, LIN Randall, Wingeier Brett
Принадлежит:

A system for electrically stimulating a user comprising: a first housing portion defining an array of openings; an array of permeable bodies with portions exposed through the array of openings and wetted with a solution that facilitates electrical coupling between the system and a body region of the user, wherein each permeable body has a cavity at a proximal portion and a distal portion and is configured to transmit the solution to the body region of the user; a substrate region defining an array of protrusions configured to support the array of permeable bodies and composed of a conductive polymer; and a set of conductors in communication with the substrate region and including a first conductor that provides a first subset of the array of permeable bodies with a first polarity and a second conductor that provides a second subset of the array of permeable bodies with a second polarity. 1. A system for electrically stimulating a user , the system comprising:a first housing portion defining an array of openings at a broad surface;an array of permeable bodies with distal portions exposed through the array of openings and treated with an electrolyte that facilitates electrical coupling between the system and a body region of the user during use;a substrate region defining an array of protrusions corresponding to and configured to support the array of permeable bodies, the substrate region composed of a conductive polymer composition; 'wherein the first subset forms a first rectangular subarray, the second subset forms a second rectangular subarray adjacent a first side of the first rectangular subarray, and the third subset forms a third rectangular subarray adjacent a second side of the first rectangular subarray; and', 'a set of conductors in communication with the substrate region, the set of conductors including a first conductor configured to provide a first subset of the array of permeable bodies with a first polarity and a second conductor configured to provide ...

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Номер записи: 91
28-01-2016 дата публикации

WEARABLE THERAPEUTIC DEVICE

Номер: US20160022982A1
Автор: Kaib Thomas E., Oskin Emil, Volpe Shane S.
Принадлежит:

A wearable therapeutic device includes a garment configured to be worn on a torso of a patient. The garment has an anterior portion and a posterior portion. The garment is configured to house at least one defibrillator component, a first therapy electrode disposed in the anterior portion of the garment, a second therapy electrode disposed in the posterior portion of the garment, and an alarm module configured to alert the patient of an impending defibrillation shock from the at least one defibrillator component to be delivered by at least one of the first therapy electrode and the second therapy electrode. The first therapy electrode and the second therapy electrode are configured to be electrically coupled to the at least one defibrillator component. At least one of the first therapy electrode and the second therapy electrode is at least one of woven into the garment and comprises a textile material. 1. A wearable therapeutic device comprising:at least one defibrillator component;a first therapy electrode and a second therapy electrode configured to be electrically coupled to the at least one defibrillator component;an alarm module configured to alert the patient of an impending defibrillation shock from the at least one defibrillator component to be delivered by at least one of the first therapy electrode and the second therapy electrode; anda garment configured to be worn on a torso of a patient, the garment having an anterior portion and a posterior portion, the garment configured to house the at least one defibrillator component, the first therapy electrode in the anterior portion of the garment, and the second therapy electrode in the posterior portion of the garment,at least one of the first therapy electrode and the second therapy electrode being at least one of woven into the garment and formed from a textile material.2. The wearable therapeutic device of claim 1 , wherein the garment is further configured to house a third therapy electrode in the posterior ...

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Номер записи: 92
28-01-2016 дата публикации

DEVICE AND METHOD FOR THE APPLICATION OF A TRANSCUTANEOUS ELECTRICAL STIMULATION STIMULUS

Номер: US20160022987A1
Автор: FRENKEL Wolf Gerhard, HARTLEP Andreas, HYCA Martin, ZSCHAECK Thomas
Принадлежит:

A device for the application of a transcutaneous electric stimulation stimulus onto the surface of a section of the human ear, which comprises a number of electrodes, wherein the device comprises a controlling device which controlling device is designed for the application of a stimulation current which is applied via the electrodes according to a predetermined run of the stimulation current along the time. To allow an effective treatment of different diseases by means of a transcutaneous stimulation of the vagus nerve the invention proposes that the stimulation device creates a periodic recurrent stimulation current, wherein the frequency of the recurrent stimulation current is between 0.01 Hz and 10 Hz. Furthermore, the invention relates a method for the treatment of migraine. 1. A device for applying a transcutaneous electric stimulation stimulus onto a surface of a section of the human ear , the device comprising: a number of electrodes; a controlling device designed for applying a stimulation current which is applied via the electrodes according to a predetermined run of the stimulation current over time , wherein the device creates a periodic recurrent stimulation current , wherein the recurrent stimulation current has a frequency between 0.01 Hz and 10 Hz.2. The device according to claim 1 , wherein the frequency of the recurrent stimulation current is between 0.1 Hz and 5 Hz.3. The device according to claim 2 , wherein the frequency of the recurrent stimulation current is between 0.5 Hz and 2 Hz.4. The device according to claim 3 , wherein the frequency of the recurrent stimulation current is between 0.75 Hz and 1.25 Hz.5. The device according to claim 1 , wherein the recurrent stimulation current is biphasic.6. The device according to claim 1 , wherein the device creates current pulses with a predetermined duration which are interrupted by current-free phases.7. The device according to claim 6 , wherein the current pulses have a duration between 100 μs and ...

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Номер записи: 93
28-01-2016 дата публикации

ELECTRO-STIMULATION DEVICE AND METHOD OF SYSTEMATICALLY COMPOUNDED MODULATION OF CURRENT INTENSITY WITH OTHER OUTPUT PARAMETERS FOR AFFECTING BIOLOGICAL TISSUES

Номер: US20160022989A1
Автор: PFEIFER Geoffrey
Принадлежит:

A non-user controllable electro-therapy device has a housing for a microprocessor, power source, status indicator, activation switch, and one or more channels for electrode contact. Only the activation switch is user-accessible. The microprocessor generates a non-user controllable frequency dependent mixed electrical signal through the electrodes, wherein the mixed electrical signal is a combination of at least two different frequencies, a first frequency having a first minimum and maximum microamp range and a second frequency having a different second minimum and maximum microamp range. The higher of the two frequencies is superimposed on the lower frequency, creating a current intensity window as an envelope along a profile of the lower frequency. The mixed electrical signal is automatically applied for a pre-determined period of time, and amplitude and/or duration and/or frequencies is varied according to a pre-set schedule programmed into a controller coupled to the one or more electrodes. 1. A method to therapeutically aid tissue or biological material via direct application of a mixed electrical signal , comprising:placing at least one or more electrodes in contact with a subject tissue or biological material;initiating a triggering of the mixed electrical signal;automatically applying, via processor control, a non-user controllable frequency dependent mixed electrical signal through the one or more electrodes, wherein the mixed electrical signal is a combination of at least two different frequency signals, a first frequency signal having a first minimum and maximum microamp range and a second frequency signal having a different second minimum and maximum microamp range, wherein a higher of the two frequency signals is superimposed on the lower of the two different frequency signals, whereby a current intensity window is sustained as an envelope along a profile of the lower of the two different frequency signals; andmaintaining the application of the mixed ...

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Номер записи: 94
28-01-2016 дата публикации

MEDICAL DEVICE CONFIGURED TO TEST FOR USER RESPONSIVENESS

Номер: US20160023014A1
Автор: Clark John G., Donnelly Edward J., Kaib Thomas E., Linder Marshal W., Szymkiewicz Steven J.
Принадлежит:

A medical device is disclosed that includes one or more treatment electrodes, one or more sensors, and one or more controllers connected to the one or more treatment electrodes and one or more sensors. The medical device also includes one or more response mechanisms connected to the one or more controllers. The one or more controllers are configured to receive input from the one or more response mechanism and are also configured to determine whether a patient wearing the medical device actuated the one or more response mechanisms based, at least in part, on the input received from the one or more response mechanisms. In some disclosed embodiments, the medical device is a wearable defibrillator. 1. A wearable defibrillator comprising:at least one sensing electrode configured to sense an electrocardiogram signal of a patient wearing the wearable defibrillator;at least one treatment electrode configured to provide treatment to the patient wearing the wearable defibrillator;at least one response mechanism configured to be actuated by the patient; andat least one controller operatively connected to the at least one sensing electrode and the at least one treatment electrode and wirelessly connected to the at least one response mechanism, the at least one controller being configured toreceive the electrocardiogram signal of the patient,determine, based on at least the electrocardiogram signal of the patient, whether the patient is experiencing a cardiac arrhythmia,provide at least one prompt to elicit a response from the patient in response to determining that the patient is experiencing the cardiac arrhythmia,provide treatment to the patient via the at least one treatment electrode in response to determining that the patient is experiencing the cardiac arrhythmia and the at least one response mechanism has not been actuated, andwithhold treatment to the patient via the at least one treatment electrode in response to the patient actuating the at least one response ...

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Номер записи: 95
26-01-2017 дата публикации

Method and apparatus for noninvasive inhibition of deep vein thrombosis

Номер: US20170021157A1
Автор: James J. Czyrny, Robert E. Kaplan, Scott E. Friedman
Принадлежит: Stimmed LLC

System, device and method for providing neuromuscular electrical stimulation (NMES) to muscles of foot. The device includes an electrical signal generator for producing a wave pattern of variable frequency, duration, intensity, ramp time and on-off cycle. The device further includes surface electrodes for being positioned over the foot muscles or around ankles and attached to the signal generator. The device includes a wearable device for positioning a first electrode adjacent a heel of the wearer's foot and a second electrode adjacent an arch of the foot. The signal generator is programmed to stimulate the foot muscles and nerves. Location of the electrodes and the programming are adjusted to reduce pooling of the blood in the soleal veins of the calf and enhance venous blood flow to prevent deep vein thrombosis (DVT); to enhance venous blood flow for the post-thrombotic syndrome patient; to expedite wound healing; to reduce neuropathic pain of the foot and ankle, chronic musculoskeletal pain of the ankle and foot, and acute post-operative foot and ankle pain; and to prevent muscular atrophy of the foot muscles.

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Номер записи: 96
26-01-2017 дата публикации

ELECTRODE SYSTEM FOR ELECTRICAL STIMULATION

Номер: US20170021158A1
Автор: Bar-Or Tal, Davis Colin, Hammett Victoria, LIN Randall, Wingeier Brett
Принадлежит: Halo Neuro, Inc.

A system for electrically stimulating a user comprising: a first housing portion defining an array of openings; an array of permeable bodies with portions exposed through the array of openings and wetted with a solution that facilitates electrical coupling between the system and a body region of the user, wherein each permeable body has a cavity at a proximal portion and a distal portion and is configured to transmit the solution to the body region of the user; a substrate region defining an array of protrusions configured to support the array of permeable bodies and composed of a conductive polymer; and a set of conductors in communication with the substrate region and including a first conductor that provides a first subset of the array of permeable bodies with a first polarity and a second conductor that provides a second subset of the array of permeable bodies with a second polarity. 1. A system for electrically stimulating a user , the system comprising: 'wherein each of the array of permeable bodies has a cavity at a proximal portion and a tapered distal portion, is configured to transmit an electrolyte solution, through hair of the user, to the body region of the user during use and is composed of an olefin polymer that elastically deforms upon interfacing with the body region of the user;', 'an array of permeable bodies that facilitates electrical coupling between the system and a body region of the user during use,'}a substrate region defining an array of protrusions corresponding to and configured to reside within cavities of the array of permeable bodies, the substrate region composed of a conductive material; anda set of conductors in communication with the substrate region, the set of conductors configured to couple to an electronics subsystem for transmission of current through the set of conductors and the array of permeable bodies for electrically stimulating the user during use of the system.2. The system of claim 1 , further comprising a first ...

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Номер записи: 97
26-01-2017 дата публикации

Systems and Methods for Enabling Appetite Modulation and/or Improving Dietary Compliance Using an Electro-Dermal Patch

Номер: US20170021171A1
Автор: Diianni Steven, Faul John L., Goode Paul V., Hong Peter I., Malave Luis Jose, Perez Raul E., Stengel Brad
Принадлежит:

A wearable device for suppressing appetite or hunger in a patient includes a microprocessor, electrical stimulator and at least one electrode configured to deliver electrical stimulation to the epidermis, through a range of 0.1 mm to 10 mm or a range of 0.1 mm to 20 mm of the dermis, of a T2 frontal thoracic dermatome to a T12 frontal thoracic dermatome or meridian of the patient and/or front or back, C5-T1 dermatome across the hand and/or arm, and/or the upper chest regions. The device includes a pad, in which the electrode is disposed, for secure placement of the device on a skin surface of a patient. The device is adapted to provide electrical stimulation as per stimulation protocols and to communicate wirelessly with a companion control device configured to monitor and record appetite patterns of the patient. The control device is also configured to monitor, record, and modify stimulation parameters of the stimulation protocols. 1. A method of modulating at least one of a patient's appetite , hunger , satiety level , or satiation level comprising:providing an electrical dermal patch adapted to adhere to the patient's epidermal layer, wherein said electrical dermal patch comprises a controller, at least one electrode adapted to be in electrical contact with said patient's epidermal layer, and a pulse generator in electrical communication with the controller and said at least one electrode;defining a plurality of stimulation parameters; andprogramming the pulse generator to generate a plurality of electrical pulses using said plurality of stimulation parameters, wherein said plurality of stimulation parameters are defined such that, after applying at least one stimulation to the patient's epidermal layer, at least one of the patient's appetite, hunger, satiety level, and satiation level is modified.2. The method of wherein claim 1 , after applying at least one stimulation to the patient's epidermal layer claim 1 , the appetite of said patient decreases relative to ...

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Номер записи: 98
26-01-2017 дата публикации

Systems and Methods for Enabling Appetite Modulation and/or Improving Dietary Compliance Using an Electro-Dermal Patch

Номер: US20170021172A1
Автор: Diianni Steven, Faul John L., Goode Paul V., Hong Peter I., Malave Luis Jose, Perez Raul E., Stengel Brad
Принадлежит:

A wearable device for suppressing appetite or hunger in a patient includes a microprocessor, electrical stimulator and at least one electrode configured to deliver electrical stimulation to the epidermis, through a range of 0.1 mm to 10 mm or a range of 0.1 mm to 20 mm of the dermis, of a T2 frontal thoracic dermatome to a T12 frontal thoracic dermatome or meridian of the patient and/or front or back, C5-T1 dermatome across the hand and/or arm, and/or the upper chest regions. The device includes a pad, in which the electrode is disposed, for secure placement of the device on a skin surface of a patient. The device is adapted to provide electrical stimulation as per stimulation protocols and to communicate wirelessly with a companion control device configured to monitor and record appetite patterns of the patient. The control device is also configured to monitor, record, and modify stimulation parameters of the stimulation protocols. 1. An electrical dermal patch configured to modulate at least one of a patient's appetite , hunger , satiety level , or satiation level comprising:a housing adapted to be adhered to the patient's epidermal layer;a controller positioned within the housing;at least one electrode adapted to be in electrical contact with said patient's epidermal layer; anda pulse generator positioned within the housing and in electrical communication with the controller and said at least one electrode, wherein the pulse generator is configured to generate a plurality of electrical pulses, said plurality of electrical pulses being defined by a plurality of stimulation parameters, wherein said plurality of stimulation parameters are selected such that at least one of the patient's appetite, hunger, satiety level, and satiation level modulates from a first state, prior to stimulation, to a second state after stimulation.2. The electrical dermal patch of wherein the appetite of said patient claim 1 , in the first state claim 1 , is greater than the appetite of ...

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Номер записи: 99
26-01-2017 дата публикации

System and method for medical devices and pain reduction

Номер: US20170021173A1
Автор: Andreas Peneder
Принадлежит: Individual

A method and system providing pain relief by applying electromagnetic impulses to nerves which transport the pain signals from the areas effected by pain to the correlated pain receptors in the brain. An array of two or more topical sensors, applied above the pain-conducting nerve read the electro-magnetic waves emitted by the respective nerve duct; one or more pulse generators emit an electromagnetic wave designed to cancel the pain signal by ways of destructive interference.

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Номер записи: 100