ПРОИЗВОДНЫЕ ГУАНИДИНА, СПОСОБ ИХ ПОЛУЧЕНИЯ И ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ, ОБЛАДАЮЩАЯ ГИПОГЛИКЕМИЧЕСКОЙ АКТИВНОСТЬЮ

Предложены производные гуанидина формулы I, представленной в описании, и их фармацевтически приемлемые соли, где R1 является необязательно замещенным фенилом, R2 является необязательно замещенным амином, R3 - H или (C1-C4) алкил, R4-H1(C1-C6) алкил, карбоциклическое кольцо с 3-7 атомами углерода и др. R5-H1, галоид, (C1-C4) алкил, (C1-C3 )алкокси, S(O)m R8 и др., предложен также способ их получения, а также фармацевтическая композиция, обладающая гипогликемической активностью. 3 с. и 11 з.п. ф-лы, 2 табл.

АМИНОПРОИЗВОДНЫЕ, СПОСОБ ИНГИБИРОВАНИЯ СИНТЕЗА ОКСИДА АЗОТА, СПОСОБ СЕЛЕКТИВНОГО ИНГИБИРОВАНИЯ СИНТЕЗА ОКСИДА АЗОТА, ПРОДУЦИРУЕМОГО ИНДУЦИРУЕМОЙ NO-СИНТАЗОЙ, СПОСОБ СНИЖЕНИЯ УРОВНЯ ОКСИДА АЗОТА, ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ

Изобретение относится к новым аминопроизводным формулы (I), где R1 - R4 - атомы водорода; X - алкилен с 1 - 6 атомами углерода; Y - низший алкил; B - NR5R11, где R5 - атом водорода, R11 выбран из 5 - 6-членного гетероциклического радикала, в котором один кольцевой член является углеродом и 1 - 4 члена - гетероатомами азота или серы, или их фармацевтически приемлемые соли, полезные как ингибиторы синтеза оксида азота. Предложены также способ ингибирования синтеза оксида азота, способ селективного ингибирования синтеза оксида азота, продуцируемого индуцируемой NO-синтазой, способ снижения уровня оксида азота и фармацевтическая композиция. 5 з.п. ф-лы, 1 табл.

PROCESS FOR PREPARING (2-MORPHOLINOPHENYL) GUANIDINES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF

Способ получения хлоргидрата хдорацетамидина

Способ получения амидина перфторсебациновой кислоты

Способ получения хлоргидрата ацетамидина

Способ получения производных формамидина

AMIDINO-DERIVATE UND IHRE VERWENDUNG ALS NO-SYNTHASE INHIBITOREN

AMINOSÄUREDERIVATE, DIESE VERBINDUNGEN ENTHALTENDE ARZNEIMITTEL UND VERFAHREN ZU IHRER HERSTELLUNG

CHLORINATED MANDELAMIDINES

... 1415709 Chlorinated mandelamidines M SOUCHARD 23 Nov 1973 [24 Nov 1972] 54618/73 Heading C2C Novel 2 - ( - hydroxy - 2 - chlorobenzyl)- #2-imidazoline, in the form of its hydrochloride salt, is prepared by treating o-chlorobenzaldehyde with aqueous sodium bisulphite, aqueous KCN and HCl and reacting the resulting 2-chloromandeliminoethyl ether hydrochloride with ethylene diamine. Novel 2 - ( - acetyloxy - 2 - chlorobenzyl)- #2-imidazoline, in the form of its hydrochloride salt, is prepared by treating 2-(-hydroxy-2- chlorobenzyl) - #2 - imidazoline hydrochloride with acetic anhydride. Novel 3,4 - dichloromandelamidrazone, in the form of its hydrochloride salt, is prepared by reacting 3,4-dichloromandeliminoethyl ether hydrochloride with hydrazine monohydrate. Novel. 2 - ( - hydroxy - 2,6 - dichlorobenzyl)- #2 - imidazoline, in the form of its hydrochloride salt, is prepared by reacting 2,6- dichloromandelimino-ethyl ether hydrochloride with ethylene diamine ...

Therapeutic N-(2-biphenylyl)guanidine derivatives

SUBSTITUTED DIAMINO-THIADIAZOLES

SUBSTITUTED DIAMINO-THIADIAZOLES

Formamidines and Pesticidal Preparations containing them

... 1,191,581. Pesticides containing amidines. CIBA Ltd. 16 Jan., 1968 [26 Jan., 1967], No. 2354/68. Heading A5E. [Also in Division C2] Pesticidal compositions comprise as active ingredient amidines of a general formula: on acid salts thereof wherein R 1 represents an aliphatic, cycloaliphatic, cycloaliphatic-aliphatic or araliphatic radical, R 2 and R 3 each represent an aliphatic radical containing 1-4 C atoms and R 2 may also represent a hydrogen atom if R 1 and R 3 do not represent the same substituted or unsubstituted alkyl radical, or wherein R 2 and R 3 together with the nitrogen atom to which they are bonded represent a 5-membered to 7-membered heterocyclic structure optionally containing further hetero-atoms, together with a suitable carrier. The composition may be in the form of dusts, emulsions or wettable powders and other fungicidal agents may be incorporated such as thiocarbamates, for example, Maneb, Zineb, Ferbam and Ziram, and also thiurams for example, TMTD, DPTD, Metiram, ...

Tricyclic vascular damaging agents

Halogenated amidino amino acid derivatices useful as nitric oxide synthase inhibitors

Halogeneted amidino amino acid derivatives useful as nitric oxide synthase inhibitors.

Halogenated amidino amino acid derivatives useful as nitric oxide synthase inhibitors of formula (i)or a pharmaceutically acceptable salt thereof, wherein all substituents are described in the specification.

Halogenated amidino amino acid derivatives useful as nitric oxide synthase inhibitors.

New compounds derived from formamidines substituted.

Mixed inhibitors of No synthase and the cyclooxygenase a process for their preparation and of the therapeutic compositions the container

1,4-Diamino-2,3-Dihydroxybutanes.

substituted 3,4-Diamino-1,2,5-thiadiazoles having an antagonistic activity of receiver-H2 of histamine.

Derived from acids phénoxy-phénoxy-alcanoïques and compounds connected, usable in products weedkillers.

Halogenated amidino amino acid derivatices useful as nitric oxide synthase inhibitors

NEW SUBSTITUTED SUCCINIC ACID METAL BETA LACTAMASE INHIBITORS AND YOUR USE FOR THE TREATMENT OF BACTERIAL INFECTIONS

HERBICIDES MEANS

VERFAHREN ZUR HERSTELLUNG VON NEUEN N'-(AMINOACYLAMINOPHENYL)-ACETAMIDINEN UND DEREN SAUREADDITIONSSALZEN

PROCEDURES FOR THE PRODUCTION OF ARYL ETHANOL DIAMINES THE WHEN AGONISTEN THE BETA-3-ADRENOCEPTORS USEFUL ARE

THIADIAZOL DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE ILLNESSES

AMIDINDERIVATE AS SELECTIVE NMDA RECEPTOR ANTAGONISTS

HERBIZIDE MITTEL

PROCEDURE FOR the PRODUCTION OF NEW ONE 3 (AMINO OR SUBSTITUTED AMINO) - 4 (AMINO SUBSTITUTED) - 1.2, 5-THIADIAZOLEN

PROCEDURE FOR THE PRODUCTION OF NEW AMINE DERIVATIVES OF GLYCERIN ETHERS

PROCEDURE FOR the PRODUCTION OF NEW ONES N' (AMINOACYLAMINOPHENYL) - ACETAMIDINEN AND THEIR SOUR ADDITION SALTS

AMINO ACID DERIVATIVES AS NO-SYNTHASEINHIBITOREN

THE ANTIBIOTIC TAN-749 AEHNLICHE CONNECTIONS AND YOUR PRODUCTION.

4-PHENOXY-3-HYDROXY-BUTYRAMIDOXIMDERIVATE, PROCEDURE FOR YOUR PRODUCTION AND IT ABSTENTION PHARMACEUTICAL MEANS.

Procedure for the production new secondary p-Aminophenylamidine as well as their acid addition salts

Procedure for the production new secondary p-Aminophenylamidine as well as their acid addition salts

Procedure for the production new secondary p-Aminophenylamidine as well as their acid addition salts

AMINOTETRAZOLDERIVATE AS NITROGEN MONOXIDE SYNTHASEINHIBITOREN

Roentgen contrast means

AMIDE IN DERIVATIVES WITH NITROGEN OXIDE SYNTHEASE ACTIVITY

AMINOTETRAZOL DERIVATIVES USABLE AS NITROGEN OXIDE SYNTHASE INHIBITORS

AMIDINO DERIVATIVES AND YOUR USE AS NO SYNTHASE INHIBITORS

MORE ENZYMHEMMER

L-N6 (1-IMINOETHYL) - LYSINDERIVATE, WHICH WHEN NITROGEN OXIDE SYNTHASEINHIBITOREN USEFUL ARE

PROCEDURE FOR THE PRODUCTION OF INDAN SIMILAR CONNECTIONS

NEUROPROTECTIVE CONNECTIONS

2-amino-2-alkyl-5 heptenoic and heptynoic acid derivatives useful as nitric oxide synthase inhibitors

Thiadiazole derivatives for the treatment of neuro degenerative diseases

Imines as ion channel modulators

ACYLAMINO-PHENYL-ACETAMIDINE COMPOUNDS

HERBICIDAL COMPOUNDS CONTAINING PHENOXYPHEN-OXYPROPYL DERIVATIVES AND THIO ANALOGUES

SUBSTITUTED 3,4-DIAMINO-1,2,5-THIADIAZOLES

Neuroprotective agents

Coumpounds active at a novel site on receptor-operated calcium channels useful for treatment of neurological disorders and diseases

Creatine analogs having antiviral activity

AMINOPHENYLAMIDINES, THEIR PRODUCTION AND THEIR PHARMACEUTICAL USE

SWITCHABLE HYDROPHILICITY SOLVENTS AND METHODS OF USE THEREOF

A solvent that reversibly converts from a hydrophobic liquid form to hydrophilic liquid form upon contact with water and a selected trigger, e.g., contact with CO2, is described. The hydrophilic liquid form is readily converted back to the hydrophobic liquid form and water. The hydrophobic liquid is an amidine or amine. The hydrophilic liquid form comprises an amidinium salt or an ammonium salt.

AMIDINES

HALOGENATED AMIDINO AMINO ACID DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS

Halogenated amidino amino acid derivatives useful as nitric oxide synthase inhibitors of Formula (I) or a pharmaceutically acceptable salt thereof, wherein all substituents are described in the specification.

ACETAMIDINE URINARY ANTISEPTICS

4-ACYLAMINOPHENYLACETAMIDINES AND A METHOD FOR THEIR PREPARATION

COLCHINOL DERIVATIVES AS VASCULAR DAMAGING AGENTS

The invention relates to the use of compounds of formula (I): wherein X is - C(O)-, -C(S)-, -C=NOH, or -CH(R7)- wherein R7 is hydrogen, hydroxy, C1- 7alkoxy, -OR8 or -NR8R9 (wherein R8 is a group -Y1R10 (wherein Y1 is a direct bond, -C(O)-, -C(S)-, -S-, -C(O)O, -C(O)NR11-, -SO2- or -SO2NR12- (wherein R11 and R12, which may be the same or different, each independently represents hydrogen, C1-3alkyl or C1-3alkoxyC2-3alkyl) and R10 is as defined herein, and R9 includes hydrogen; R1, R2 and R3 are as defined herein and are preferably methyl; R4, R5 and R6 are as defined herein with the proviso that R5 is not hydroxy, alkoxy, substituted alkoxy, -OPO3H2, -O-C1-7alkanoyl or benzyloxy; and salts thereof in the manufacture of a medicament for use in the production of a vascular damaging effect in warm-blooded animals such as humans. The present invention further relates to compounds of the formula (I), pharmaceutical compositions containing them, processes for their preparation and to a method ...

CATALYSTS CONTAINING PER-ORTHO ARYL SUBSTITUTED ARYL OR HETEROARYL SUBSTITUTED NITROGEN DONORS

Catalyst compositions useful for the polymerization of olefins are disclosed. These compositions comprise a Group 8-10 metal complex comprising a bidentate or variable denticity ligand comprising two nitrogen donor atoms independently substituted by an aromatic of heteroaromatic ring(s), wherein the ortho positions of said ring(s) are substituted by aryl or heteroaryl groups. Also disclosed are proceses for the polymerization of olefins using the catalyst compositions.

USE OF AN IONIC COMPOUND, DERIVED FROM MALONONITRILE AS A PHOTOINITIATOR, RADICAL INITIATORS OR CATALYSER IN POLYMERIZATION PROCESSES OR AS A BASIC DYE

La présente invention concerne l'utilisation de composés ioniques dérivés du malononitrile comme photoinitiateur source d'acide catalyseur dans un procédé de polymérisation ou de réticulation de monomères ou de prépolymères capables de réagir par voie cationique, ou comme catalyseur dans un procédé pour la modification de polymères. L'invention vise également l'utilisation de composés ioniques dérivés du malononitrile dans les colorants cationiques.

AMIDINO DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS

The current invention discloses amidino derivatives useful as nitric oxide synthase inhibitors.

DUAL INHIBITORS OF NO SYNTHASE AND CYCLOOXYGENASE, PROCESS FOR THEIR PREPARATION AND THERAPEUTICAL COMPOSITIONS CONTAINING THEM

The invention relates to compounds of the general formula AB, which may be a salt or an amide, wherein: - A represents a cyclooxygenase inhibitor having an accessible acidic functi on and - B represents the L-form of arginine analogues of the formula wherein R1, R2 and R3 represent various substituents, process for the preparation of such compounds and pharmaceutical composition thereof.

O-BENZYL OXIME ETHER DERIVATIVES AND THEIR USE AS PESTICIDES

Compounds of formula (I), wherein Y is hydrogen, C1-C4alkyl, C1-C4alkoxy, OH, CN, NO2, Si(CH3)3, CF3 or halogen, and T is a group (a) or (b), and wherein the remaining substituents have the following definitions: X is O, S or NR13; A is O or NR4; R1 is hydrogen, C1-C4alkyl, halo-C1-C4alkyl, cyclopropyl, C1C4alkoxymethyl, C1-C4alkoxy, C1-C4alkylthio or cyano; R2 is hydrogen, C1C6alkyl, C3-C6cycloalkyl, cyano unsubstituted or substituted C1C6alkoxycarbonyl, unsubstituted or substituted di(C1-C6alkyl)aminocarbonyl, unsubstituted or substituted C1-C6alkyl-S(O)q, unsubstituted or substituted aryl-S(O)q, unsubstituted or substituted heteroaryl, unsubstituted or substituted heterocyclyl, unsubstituted or substituted heterocyclylcarbonyl or unsubstituted or substituted phenyl; and R3 is hydrogen, unsubstituted or substituted alkyl, unsubstituted or substituted C3-C6cycloalkyl, unsubstituted or substituted phenyl or unsubstituted or substituted pyridyl; and wherein the remaining substituents are ...

SURFACE MODIFIED CARBONATE MATERIALS

Greffage d'un polymère à la surface d'un matériau carboné comportant des fonctions carboxyles, amines et/ou hydroxyles à sa surface. On met ce matériau en suspension dans une solution comprenant le polymère à greffer, lequel comporte une fonction carboxyle, amine et/ou hydroxyle, la solution comprenant aussi un solvant du polymère. On effectue ensuite un traitement provoquant la déshydratation en une fonction carboxyle, d'une fonction amine et/ou hydroxyle et l'on greffe ainsi le polymère sur le matériau carboné par des liens esters ou amides. Utilisation dans la cathode ou l'anode d'un générateur électrochimique, dans un matériau polymère peu polaire, dans une encre, et comme dépôt conducteur sur un plastique flexible utilisé comme contact électrique, comme protection électromagnétique ou comme protection antistatique.

Procédé de préparation de dérivés de la mandélamidine

Röntgenkontrastmittel und Verfahren zu dessen Herstellung

VERFAHREN ZUR HERSTELLUNG VON NEUEN AMIDINEN.

Verfahren zur Herstellung von N-Vinylamidinen

Phenoxyalkyl amidines having blood pressure reducing

... (A) Phenoxyalkyl amidines of the general formula (I): - where Z3 and Z4=hydrogen, halogen, alkoxy (1 to 4C atoms) or trifluoromethyl, but one of the two groups Z3 or Z4 must be hydrogen. - (B) Pharmaceutical preparations contng. (I). - The compounds have blood pressure reducing properties and are active orally.

Schädlingsbekämpfungsmittel

VERFAHREN ZUR HERSTELLUNG VON NEUEN AMIDINEN.

AMINE DERIVATIVES AND AMIDINES AMINOHETEROCYCLE AND [...] AND MEDICAMENT COMPRISING THE SAME.

[...] DE [...] DE [...] PHENYL- [...][...].

PROCEDURES FOR the PRODUCTION OF N, N' DISUBSTITUIERTEN NAPHTHYLACETAMIDINEN.

Herbicide

Phenylamidine derivatives useful especially in therapeutics

The phenylamidine derivatives correspond to the formula in which Ar represents an aryl group (especially an alpha -naphthyl, beta -naphthyl or phenyl group) which can be substituted by one or a number of C1-C4 alkyl, C1-C4 alkoxy, methylenedioxy, halogen, CF3, NH2 or NO2 groups; A represents the -CH2-, -CHOH-, -CH2O-, -CH2S-, -CH2NH-, -OCH2-, -SCH2-, -NH-, -NHCOCH2-, -CH2NHCH2- or -NHCH2- group; Y represents O or NH; B represents a single bond or can, when A is CH2S, represent a -CH2- or -CH(CH3)-group; their acid addition salts when Y = NH and metal salts when Y = O are also concerned. These derivatives and their salts are useful in therapeutics.

[...] SALTS AND METHOD FOR SYNTHESIZING 2-NAPHTHALENE-TO-[...] D, NON-DISUBSTITUTED FROM SAID SALTS.

Azo-di-isobutyric acid-(N,N-hydroxyalkyl)-amidines

An azo di-isobutyric acid-(N,N'-hydroxyalkyl)-amidine corresponding to the formula (I): <IMAGE> (I) in which R and R', which may be the same or different, represent linear or branched alkylene radicals containing from 2 to 4 carbon atoms, and X represents R'-OH or H.

Metal complexes with N-amino-amidinate ligands

Die Erfindung betrifft neue Metallkomplexe mit N-Amino-Amidinat-Liganden, insbesondere Metallkomplexe mit N,N'-Bis(dimethylamino)-acetamidinat-, N,N'-Bis(dimethylamino)-formamidinat- und N-Dimethylaminoacetamidinat-Liganden sowie ihre Herstellung und Verwendung. Die Metallkomplexe weisen einen fünfgliedrigen Chelatring auf. Die Metallkomplexe werden mit den Metallen aus den Hauptgruppen des PSE aber auch mit Nebengruppenelementen wie Tantal (Ta), Eisen (Fe), Kobalt (Co), Nickel (Ni), Kupfer (Cu) oder (Zink), sowie mit Edelmetalle wie Palladium (Pd) gebildet. Die erfindungsgemäßen Komplexe finden Verwendung als Precursoren zur Herstellung von funktionellen Schichten mittels Gasphasen-Dünnschichtverfahren wie CVD, MO-CVD und ALD. Weiterhin können sie als Katalysatoren für die Olefin-Hydroaminierung und für die Olefin-Polymerisation eingesetzt werden. The invention relates to new metal complexes with N-amino-amidinate ligands, in particular metal complexes with N, N'-bis (dimethylamino) -acetamidinate, N, N'-bis (dimethylamino) -formamidinate and N-dimethylaminoacetamidinate ligands and their Manufacture and use. The metal complexes have a five-membered chelate ring. The metal complexes are formed with the metals from the main groups of the PSE but also with sub-group elements such as tantalum (Ta), iron (Fe), cobalt (Co), nickel (Ni), copper (Cu) or (zinc), as well as with noble metals such as palladium (Pd) formed. The complexes according to the invention are used as precursors for the production of functional layers by means of gas phase thin-film processes such as CVD, MO-CVD and ALD. They can also be used as catalysts for olefin hydroamination and for olefin polymerization.

Process

Preparation of lanthanide-containing precursors and deposition of lanthanide-containing films

본원에는 희토류 금속 함유 층을 증착하기 위한 방법 및 조성물이 기술되어 있다. 일반적으로, 개시된 방법은 증착 방법, 예를 들어 화학 기상 증착법 또는 원자층 증착법을 사용하여 희토류 함유 화합물을 포함하는 전구체 화합물을 증착한다. 개시된 전구체 화합물은 치환기로서 1종 이상의 지방족 기를 갖는 시클로펜타디에닐 리간드 및 아미딘 리간드를 포함한다. Methods and compositions for depositing rare earth metal containing layers are described herein. Generally, the disclosed method deposits precursor compounds comprising rare earth-containing compounds using deposition methods, such as chemical vapor deposition or atomic layer deposition. The disclosed precursor compounds include cyclopentadienyl ligands and amidine ligands having at least one aliphatic group as a substituent.

Azo-diisobutyryl-(N,N'-hydroxyalkyl)-amidines, their preparation and their use as polymerisation initiators, as crosslinking agents and as blowing agents

Die Erfindung betrifft Azo-di-isobuttersäure-(N,N'-hydroxialkyl)-amidine der Formel <IMAGE> worin R und R' lineare oder verzweigte Alkylenreste mit 2 bis 4 C-Atomen, und X R'-OH oder H bedeuten; ein Verfahren zu ihrer Herstellung, sowie ihre Verwendung als Polymerisationsinitiatoren, als Vernetzungsmittel und als Treibmittel bei der Herstellung von Schaumstoffen. The invention relates to azo-di-isobutyric acid (N, N'-hydroxyalkyl) amidines of the formula <IMAGE> in which R and R 'are linear or branched alkylene radicals having 2 to 4 carbon atoms, and X is R'-OH or H. ; a process for their preparation, and their use as polymerization initiators, as crosslinking agents and as blowing agents in the production of foams.

Azo di:isobutyric (N,N'-hydroxyalkyl) amidine(s) - for use as polymerisation initiators, crosslinking and blowing agents

New azo di-isobutyric (N,N'-hydroxyalkyl) amidines are of formula (I): (in which R and R' are 2-4C alkylene; X is R'-OH or H). (I) are useful as free radical initiators in polymerisation or crosslinking processes opt. with foaming, and as blowing agents in prodn. of foams. Dispersions with improved stability are obtd., without coagulation or corrosion problems during polymerisation. Polymers with hydrophilic hydroxy-alkyl end gps. are obtd., crosslinkable with formaldehyde resins and giving coatings with improved adhesion and water resistance.

Polymerisation using azo di-isobutyric amidine(s) as initiators - giving dispersions with improved stability and adhesion

Prodn. of polymers is effected using as initiators cpds. of formula (I): (in which R and R1 are 2-4C alkylene; X is H or R1-OH), in mass or soln. polymerisation. Prods. are used as bonders for stoving lacquers and corrosion resistant coating on metals. Dispersions with improved stability are obtd. without coagulation or corrosion problems during polymerisation. Polymers with hydrophilic hydroxyalkyl end-gps. are obtd., crosslinkable with formaldehyde resins and showing improved adhesion to substrates.

Procedimiento para la obtencion de (n,n'-hidroxialquil)-ami-dinas de acido azo-di-isobutirico

1. Procedimiento para la obtención de (N,N''-hidroxialquil)- amidinas de ácido azo-di-isobutírico de fórmula **(Fórmula)** donde R y R''significan restos alquileno lineales o ramificados con 2 hasta 4 átomos y X significa R''-CH ó H, caracterizado porque iminoalquiléteres de ácido azo-di-isobutírico con 1 - 4 átomos de carbono en el grupo alquilo, se hace reaccionar con como mínimo una monoalcanolamina con 2 - 4 átomos de carbono o con una mezcla de como mínimo una monoalcanolamina y como mínimo una dialcanolamina, en cada caso con 2 - 4 átomos de carbono en el resto alcanol, siendo la proporción molar entra las mono - y dialcanolaminas de 1:1, a temperaturas de unos 0 hasta 50ºC en proporciones cuantitativas aproximadamente equivalentes.

EMULSIFYING AZOINITIATORS AND THEIR USE

A Process for the Production of Azo-Diisobutyric Acid Amidine

1,198,782. Azo-di-isobutyric acid amidine. FARBENFABRIKEN BAYER A.G. 30 Oct., 1968 [30 Jan., 1968], No. 51389/68. Heading C2C. Azo-di-isobutyric acid amidine may be prepared by treating a salt thereof, particularly the bis-hydrochloride, with an aqueous alkali metal hydroxide solution, preferably 10-20% aqueous NaOH, at a temperature of from - 15‹ to +25‹ C., separating the free base, washing with a polar solvent until substantially free of water and then drying in a conventional manner.

Patent JPH0216294B2

Method of imidodiacetonitrile synthesis

FIELD: organic synthesis. SUBSTANCE: product: imidodiacetonitrile. Reagent 1: hexamethylenetetramine or ammonia. Reagent 2: hydrogen cyanide. Reaction condition: aqueous medium, in the presence of inorganic acid, at temperature range from 50 C to boiling point, pH of reaction medium is made up to 5.5-10, and reaction mass is heated up to 50-100 C for time that is sufficient for by-products conversion. EFFECT: improved method of synthesis. 4 cl Эс Ос ПЧ Го РОССИЙСКОЕ АГЕНТСТВО ПО ПАТЕНТАМ И ТОВАРНЫМ ЗНАКАМ (19) (51) МПК ВИ” 2017 726 ' 13) Сл С 07 С255/24 12) ОПИСАНИЕ ИЗОБРЕТЕНИЯ К ПАТЕНТУ РОССИЙСКОЙ ФЕДЕРАЦИИ (21), (22) Заявка: 4830789/04, 13.08.1990 (30) Приоритет: 14.08.1989 1$ 394039 (46) Дата публикации: 15.08.1994 (56) Ссылки: Патент США М 3886138, кл. С 07С121/42, 1972.Патент США М 3988360, кл. С 07С120/00, 1975.Патент США М 4307037, кл. С 07С120/00, 1918. (71) Заявитель: Монсанто Компани (1$) (72) Изобретатель: Карл Эрик Кени[ЦЗ], Гери Эллен Лэнсер[Ц$], Пол Арсер Моррисон[Ц$], Роберт Беллер Уайзенфельд[Ц$] (73) Патентообладатель: Монсанто Компани (1$) (54) СПОСОБ ПОЛУЧЕНИЯ ИМИДОДИАЦЕТОНИТРИЛА (57) Реферат: Использование: в органическом синтезе. Сущность: усовершенствованный ‘способ получения иминодиацетонитрила. Реагент 1: Гексаметилентетрамин или аммиак. Реагент 2: Цианистый водород. Условия реакции: Водная среда в присутствии неорганической кислоты, температурный интервал от 50°С до температуры кипения, рН реакционной массы доводят до 5,5 - 10 и реакционную массу нагревают до 50 - 100°С в течение времени, достаточного для превращения побочных продуктов. Цель - повышение выхода целевого продукта. 3 з.п. ф-лы. 2017726 С1 КО Эс Ос ПЧ Го (19) КУЗЗАМ АСЕМСУ ГОК РАТЕМТ$ АМО ТКАОЕМАКК$ 12) АВЗТКАСТ ОЕ 1МУЕМТОМ ВИ "” 2017 726. 611 51° @ 07 С255/24 13) СЛ (21), (22) АррИсаНоп: 4830789/04, 13.08.1990 (30) Рпогу: 14.08.1989 Ц$ 394039 (46) Рае о! рибИсаНоп: 15.08.1994 (71) АррИсапе: МОМЗАМТО КОМРАМ! (ЦЗ) (72) шпуетог: КАКЕ ЕНЕК КЕМ!С[0$], СЕН! ЕНЕЕЕМ ЕЕНМЗЕК[У$], РОЕ ...

Atomic layer deposition using metal amidinates

金属薄膜在均匀厚度和优良阶梯覆盖下沉积。铜金属薄膜通过交替量的N，N′-二异丙基乙脒铜(I)和氢气的反应沉积在加热的底材上。钴金属薄膜通过交替量的N，N′-二异丙基乙脒钴(II)和氢气的反应沉积在加热的底材上。这种金属的氮化物和氧化物可分别用氨或水蒸气代替氢气形成。细孔中的薄膜具有非常均匀的厚度和良好的阶梯覆盖。合适的应用包括微电子器件中和磁信息存储器件中磁致电阻的电连接。

Atomic Layer Deposition Using Metal Amidinates

금속 필름이 균일한 두께 및 우수한 스텝 커버리지로 증착된다. 구리 금속 필름을 가열된 기판에 구리(I) N, N'-디이소프로필아세트아미디네이트 증기와 수소 가스를 교대로 반응시켜서 증착시킨다. 코발트 금속 필름을 가열된 기판에 코발트(II) 비스(N, N'-디이소프로필아세트아미디네이트) 증기와 수소 가스를 교대로 반응시켜서 증착시킨다. 이들 금속의 질화물 및 산화물을 수소를 암모니아 또는 수증기로 각각 교체함으로써 형성할 수가 있다. 필름은 좁은 홀에도 매우 균일한 두께 및 우수한 스텝 커버리지를 갖는다. 적당한 응용분야로는 자기정보 저장장치에서의 마이크로전자 및 자기저항 층의 전기적 상호연결에 사용된다.

A noble transition metal complex including bisamidine moiety and method for olefin polymerization using the same

본 발명은 하기 화학식 A로 표시되는 착화합물 및 이를 포함하는 올레핀 중합용 촉매 조성물에 관한 것으로, 상기 화학식 A 중, M, Ar1, Ar2, R1 및 R2과 상기 고리그룹 B는 발명의 상세한 설명 내 기재된 바와 동일하다. [화학식 A] The present invention relates to a complex represented by the following formula (A) and a catalyst composition for olefin polymerization comprising the same, wherein M, Ar1, Ar2, R1 and R2 and the ring group B are as defined in the description of the invention same. (A)

Bisaminophenyl-based curatives and amidine-based curatives and cure accelerators for perfluoroelastomeric compositions

Process for the preparation of iminodiacetonitrile and imino-acetic acid

내용 없음. No content.

Preparation of lanthanide-containing precursors and deposition of lanthanide-containing films

本文描述了沉积含稀土金属的层的方法及组合物。概括而言，所公开的方法使用诸如化学气相沉积或原子层沉积的沉积方法沉积包含含稀土的化合物的前体化合物。所公开的前体化合物包括具有至少一个脂族基团作为取代基的环戊二烯基配体和脒配体。

Fluorinated imidoylamidines vulcanizing agents

The invention provides a compound and tautomeric forms thereof having the formula: wherein R f 1 is selected from the group consisting of hydrogen, a straight chain, branched secondary or branched tertiary C 1 -C 20 perfluoroalkyl group optionally containing ether or thioether linkages and C 1 -C 10 perfluoroalicyclic group optionally containing ether or thioether groups; R f 2 is a straight or branched C 1 -C 20 perfluoroalkylene group optionally substituted with ether and thiother linkages; and X is selected from the group consisting of fluorine and The invention also provides perfluoroelastomeric compositions cured with the perfluoroimidoylamidines of the invention as well as combinations of perfluoroimidoylamidines and other curing agents.

Method of preparing azoiminoethers and azocarboxylic acid esters, and novel mixed azocarboxylic acid esters

FIELD: organic synthesis. SUBSTANCE: method of preparing an azocarboxylic acid ester comprises synthesis an azoiminoether via reaction of azonitrile with alcohol and hydrochloric acid in aromatic solvent at HCl/azonitrile molar ratio 2-6 if alcohol is methanol and 3-6 if alcohol is ethanol or higher alcohol. Resulting azoiminoether hydrochloride is hydrolyzed by gradually adding water to reaction mixture and slowly pouring reaction mixture to water at 15 to 50 о С. Mixture of liquid azocarboxylic acid esters is prepared by synthesizing azoiminoether hydrochlorides, hydrolyzing them with water, and recovering desired esters from organic phase. Invention provides mixture of azocarboxylic acid ester salts corresponding to formula II: (II), where R1, R2, R3, and R4 represent С 1 -С 4 -alkyl groups; R and R' are independently selected from group including linear or branched aliphatic С 1 -С 4 -radicals. Invention provides liquid mixture of azocarboxylic acid esters corresponding to formula III: (III) wherein R1, R2, R3, R4, R, and R' have the same meanings as in formula II. EFFECT: increased yields and purity of products. 23 cl, 4 tbl, 6 ex ÐÎÑÑÈÉÑÊÀß ÔÅÄÅÐÀÖÈß (19) RU (51) ÌÏÊ 7 (11) (13) 2 245 872 C2 C 07 C 257/06, 245/04, 257/14 ÔÅÄÅÐÀËÜÍÀß ÑËÓÆÁÀ ÏÎ ÈÍÒÅËËÅÊÒÓÀËÜÍÎÉ ÑÎÁÑÒÂÅÍÍÎÑÒÈ, ÏÀÒÅÍÒÀÌ È ÒÎÂÀÐÍÛÌ ÇÍÀÊÀÌ (12) ÎÏÈÑÀÍÈÅ ÈÇÎÁÐÅÒÅÍÈß Ê ÏÀÒÅÍÒÓ (21), (22) Çà âêà: 2001122813/04, 07.01.2000 (72) Àâòîð(û): ÁÓÐÄÎÄÞÊ Ïîëü (FR) (24) Äàòà íà÷àëà äåéñòâè ïàòåíòà: 07.01.2000 (30) Ïðèîðèòåò: 15.01.1999 (ïï.1-23) FR 99/00391 (73) Ïàòåíòîîáëàäàòåëü(ëè): ÀÒÎÔÈÍÀ (FR) R U (43) Äàòà ïóáëèêàöèè çà âêè: 27.06.2003 (45) Îïóáëèêîâàíî: 10.02.2005 Áþë. ¹ 4 2 2 4 5 8 7 2 (56) Ñïèñîê äîêóìåíòîâ, öèòèðîâàííûõ â îò÷åòå î ïîèñêå: KELLY, DAVID P. et al: "The cross-reaction between 1-(methoxycarbonyl)-and 1-(butoxycarbonyl)-1-methylethyl: simultaneous generation of unlike radicals from an unsymmetrical azo precursor", Australian Journal of Chemistry, 1987, vol.40, no 10, p.1631-1639. EP ...

Water-absorbent resin, process for production thereof, and water-absorbent resin composition

A water-absorbent resin is produced by dispersing a solid blowing agent having an average particle diameter within a range of from 1 µm to 100 µm in an aqueous monomer solution containing an unsaturated monomer and a cross-linking agent, and then polymerizing the unsaturated monomer. The water-absorbent resin has excellent water absorption characteristics, such as improved dispersion and absorption rate of aqueous fluid, enhanced water retention capacity and dry touch, lower water-soluble component content, and lower residual monomer content. When a water-absorbent resin composition using the water-absorbent resin is used for, for example, a sanitary material, it is possible to improve the absorption rate and water retention capacity, and prevent leakage of fluid from the sanitary material.

Azoamidine compound and its use as polymerization initiator

Disclosed is a compound shown by the general formula [1]: (see fig. I) wherein R1 and R2 are independently a lower alkyl group, R3 and R4 are independently a hydrogen atom or a lower alkyl group, and X is a divalent hydrocarbon group, or its hydrate. This compound is useful as a polymerization initiator for polymerization of an .alpha.,.beta.-ethylenically unsaturated monomer.

Atomic layer deposition using metal amidinates

Metal films are deposited with uniform thickness and excellent step coverage. Copper metal films were deposited on heated substrates by the reaction of alternating doses of copper(I) NN'-diisopropylacetamidinate vapor and hydrogen gas. Cobalt metal films were deposited on heated substrates by the reaction of alternating doses of cobalt(II) bis(N,N'-diisopropylacetamidinate) vapor and hydrogen gas. Nitrides and oxides of these metals can be formed by replacing the hydrogen with ammonia or water vapor, respectively. The films have very uniform thickness and excellent step coverage in narrow holes. Suitable applications include electrical interconnects in microelectronics and magnetoresistant layers in magnetic information storage devices.

Azo-di-isobutyric acid amidine prepn useful as a

Azo-di-isobutyric acid amidine of the formula is prepared by reacting a salt of (I) with an aqueous solution of an alkali metal hydroxide at between -15 and +25 deg.C, separating the free amidine, washing it with a polar solvent until practically free from water, and then drying. Azo-di-isobutyric acid amidine is polymerisation initiator. The amidine is stable on storage. Its use as a polymerisation initiator avoids the difficulties caused by the introduction of salts onto the polymerisation system.

PROCESS FOR THE PREPARATION OF AZOIMINOETHERS AND ESTERS OF AZOCARBOXYLIC ACIDS, AND NOVEL MIXED ESTERS OF AZOCARBOXYLIC ACIDS

The invention concerns a method for preparing an azoiminoether hydrochloride which consists in reacting an azonitrile with an alcohol and hydrochloric acid in an aromatic solvent, wherein the molar ratio R = HCl/azonitrile is > 2 when the alcohol is methanol and > 3 when the alcohol is ethanol or a higher alcohol. The invention also concerns a method for preparing an azocarboxylic acid ester which consists in the synthesis of an azoiminoether hydrochloride by the inventive method and, hydrolysis in the presence of the resulting azoiminoether hydrochloride. Said methods enable to obtain liquid composition of azocarboxylic acid esters. The invention further concerns mixed azoiminoether salts of formula (II'). The invention also concerns mixed azoiminocarboxylic acid esters corresponding to the formula (III').

PROCESS FOR THE PREPARATION OF AZOIMINOETHERS AND ESTERS OF AZOCARBOXYLIC ACIDS, AND NOVEL MIXED ESTERS OF AZOCARBOXYLIC ACIDS

N-(amidino alkyl)-n-acyl-amines - as analgesics and antiinflammatory agents

Cpds. (I) and their salts. A-N(COR)-(CH2)n-B (I) (where A is Ph or cyclohexyl, R is 1-5C alkyl, phenyl or benzyl opt. halosubstd. n is 1,2 or 3, B is COORo or Ro is H, alkyl, ammonium or M1/x ; M is a metal of valency x, R3 is H, OH, 1-3C alkyl; R2 is H, OH, or 1-3C alkyl; R1 is H, R1 and R2 together with the two amidino-N atoms, is 2-DELTA2-imidazolinyl or 2 (1,4,5,6-tetrahydropyrimidyl), R3 in this case being H) are prepd. from the A-NH(CH2)nCN by acyln., then formation of the iminoether, followed by treatment with R2R3N and finally optionally treatment with NH2OH or an alkylene diamine. Thus (I,A = Ph, R= Et, n = Z and B is amidino) is prepd. by acylating beta-anilino propionitrile with (PrO)2O then reaction with EtOH, and NH3.

Method for synthesizing acetamidine, acetamidine and application thereof, and vitamin B1

本发明提供了一种合成乙脒的方法、乙脒及其应用和维生素B1，涉及化合物合成技术领域，合成乙脒的方法包括：利用盐酸乙脒与甲醇钠反应合成乙脒，在反应过程中向反应体系中加入甲酸甲酯。该方法操作简单、方便，易于实现，可以有效去除合成乙脒过程中的水分，提高乙脒的收率。

Process for the preparation of propionamidine derivatives

내용 없음. No content.

Analogous process for the preparation of an amidine or an acid addition salt thereof.

Atomic layer deposition using metal amidinates

Metal films are deposited with uniform thickness and excellent step coverage. Copper metal films were deposited on heated substrates by the reaction of alternating doses of copper(I) NN′-diisopropylacetamidinate vapor and hydrogen gas. Cobalt metal films were deposited on heated substrates by the reaction of alternating doses of cobalt(II) bis(N,N′-diisopropylacetamidinate) vapor and hydrogen gas. Nitrides and oxides of these metals can be formed by replacing the hydrogen with ammonia or water vapor, respectively. The films have very uniform thickness and excellent step coverage in narrow holes. Suitable applications include electrical interconnects in microelectronics and magnetoresistant layers in magnetic information storage devices.

Process for producing nitrogen-containing compounds

Synthesis method and application of amide crystal compound

一种有如下结构式及晶胞参数的酰胺晶体化合物(I)的合成方法是无水无氧条件下,称取二苯甲酮腙2.0968g及1.9990g一水合乙酸铜，放入250mL两口烧瓶中，加入100mL氯苯做溶剂，回流反应48小时后，柱层析分离，用石油醚/二氯甲烷(3/7)洗脱，将收集的第一组分点自然挥发，得单晶氮乙酰氨基二苯甲酮腙； 该酰胺晶体化合物(Ⅰ)的用途，是在二苯甲酮亚胺的自缩合反应作为催化剂显示了一定的催化效果，其转化率达53％。

Method for preparing azoiminoethers and azocarboxylic acid esters and novel azocarboxylic acid mixed esters

본 발명은 방향족 용매를 사용하여 아조니트릴을 알코올 및 염산과 반응시키는 단계를 포함하며, 상기 알코올로 메탄올을 사용하는 경우에는 아조니트릴에 대한 염산의 몰비(R=염산/아조니트릴)가 2를 초과하고(R>2), 알코올로서 에탄올 또는 고급 알코올(higher alcohol)을 사용하는 경우에는 아조니트릴에 대한 염산의 몰비가 3을 초과하는(R>3)것을 특징으로 하는 아조이미노에테르 염산염의 제조방법에 관한 것이다. 본 발명은 또한 본 발명의 방법에 의해 아조이미노에테르 염산염을 합성하는 단계 및 합성한 아조이미노에테르 염산염의 존재하에 가수분해시키는 단계를 포함하는 아조카르복실산 에스테르의 제조방법에 관한 것이다. 상기한 방법은 아조카르복실산 에스테르의 액체 조성물을 얻을 수 있다. 본 발명은 또한 하기 일반식 (Ⅱ')의 혼합형 아조이미노에테르염에 관한 것이다. 본 발명은 또한 하기 일반식 (Ⅲ')의 혼합형 아조이미노카르복실산 에스테르에 관한 것이다. [화학식 2] (Ⅱ') [화학식 6]

Process for the preparation of phenoxyamidines

Imino[(3-halogenophenyl)amino]acetic acid derivatives and herbicides containing same

In accordance with the present invention, there are provided novel compounds represented by the following general formula [I], and herbicides containing as their active ingredients. ##STR1## wherein X 1 , X 2 , X 3 and X 4 are each hydrogen, halogen or methyl, and R is hydrogen or a lower alkyl. There are also provided herbicides containing as their active ingredients compounds represented by the following general formula [II]. ##STR2## wherein R is hydrogen or a lower alkyl.

A PROCESS TO PREPARE 2-NAPHTHALENETHANIMIDAMIDS N, N'-OF-SUBSTITUTES AND INTERMEDIATES USED IN THIS PROCESS

Process for the production of nitrogen compounds

A process of reacting a compound having an NH group with a thiocyanate, a cyanamide, a nitrile, or an ester in the presence of a silylating agent to thereby obtain the corresponding nitrogen-containing addition or substitution product. This process enables direct and efficient synthesis of nitrogen compounds such as isothioureas, guanidines, amidines, and amides, and is universally applicable and suitable for mass production.

Metal complexes with n-aminoamidinate ligands

Composition based on copolymer of terafluoroethylene and perfluoroalkyl vinyl ethers

FIELD: polymer materials. SUBSTANCE: invention is directed to composition used in chemical and petroleum processing industries, where high thermosetting properties of rubber compound composition are required, based on terpolymer and quaternary copolymer of terafluoroethylene and perfluoroalkyl vinyl ethers including cyano group and represented by structural formulas III, IV, and V, which composition comprises as vulcanization agent perfluorodiimidoylamidins of specified formula in amount 1-4 wt parts per 100 wt parts copolymer. Technical task of present invention was to work out composition imparting bright color to vulkanizates based thereon and, along with high physicochemical characteristics, manifests elevated heat resistance in strained state and resistance to concentrated nitric acid. The task is solved by using, as vulcanization agent, above-mentioned perfluorodiimidoylamidin of specified formula. EFFECT: improved physicochemical characteristics and heat and chemical resistance. 2 cl, 3 tbl, 12 ex ÐÎÑÑÈÉÑÊÀß ÔÅÄÅÐÀÖÈß RU (19) (11) 2 319 717 (13) C1 (51) ÌÏÊ C08L 27/18 (2006.01) C08K 5/29 (2006.01) ÔÅÄÅÐÀËÜÍÀß ÑËÓÆÁÀ ÏÎ ÈÍÒÅËËÅÊÒÓÀËÜÍÎÉ ÑÎÁÑÒÂÅÍÍÎÑÒÈ, ÏÀÒÅÍÒÀÌ È ÒÎÂÀÐÍÛÌ ÇÍÀÊÀÌ (12) ÎÏÈÑÀÍÈÅ ÈÇÎÁÐÅÒÅÍÈß Ê ÏÀÒÅÍÒÓ (21), (22) Çà âêà: 2006124713/04, 10.07.2006 (72) Àâòîð(û): Ãóáàíîâ Âèêòîð Àíäðååâè÷ (RU), Êîëëàð Àëåêñàíäð Íèêîëàåâè÷ (RU), Âîëêîâà Ìàðãàðèòà Àëåêñååâíà (RU), Öûïêèíà Èðèíà Ìèõàéëîâíà (RU) (24) Äàòà íà÷àëà îòñ÷åòà ñðîêà äåéñòâè ïàòåíòà: 10.07.2006 (45) Îïóáëèêîâàíî: 20.03.2008 Áþë. ¹ 8 (54) ÊÎÌÏÎÇÈÖÈß ÍÀ ÎÑÍÎÂÅ ÑÎÏÎËÈÌÅÐÀ ÒÅÒÐÀÔÒÎÐÝÒÈËÅÍÀ È 2 3 1 9 7 1 7 ôîðìóëû, â êîëè÷åñòâå 1-4 ìàñ.÷. íà 100 ìàñ.÷. ñîïîëèìåðà. Òåõíè÷åñêîé çàäà÷åé íàñòî ùåãî èçîáðåòåíè âë åòñ ðàçðàáîòêà êîìïîçèöèè, âóëêàíèçàòû íà îñíîâå êîòîðîé èìåþò ñâåòëóþ îêðàñêó è íàð äó ñ âûñîêèìè ôèçèêîìåõàíè÷åñêèìè ïîêàçàòåë ìè îáëàäàþò ïîâûøåííîé òåïëîñòîéêîñòüþ â íàïð æåííîì ñîñòî íèè è ñòîéêîñòüþ ê êîíöåíòðèðîâàííîé àçîòíîé êèñëîòå. Ïîñòàâëåííà çàäà÷à äîñòèãàåòñ òåì, ÷òî â êà÷åñòâå ...

L-N6 -(1-iminoethyl) lysine derivatives useful as nitric oxide synthase inhibitors

There is disclosed a novel amino alcohol amine derivatives of L-N 6 -(1-iminoethyl)lysine, pharmaceutical compositions containing these novel compounds, and to their use in therapy, in particular their use as nitric oxide synthase inhibitors.

Process for the preparation of iminodiacetonitrile and iminodiacetic acid

L-n6-(1-iminoethyl)lysine derivatives useful as nitric oxide synthase inhibitors

There are disclosed derivatives of L-N6-(1-iminoethyl)lysine of general formula (I), pharmaceutical compositions containing these compounds, and to their use in therapy, in particular their use as nitric oxide synthase inhibitors. Y is a hydrogen, lower alkyl radical, lower alkenyl radical, lower alkynyl radical, aromatic hydrocarbon radical, alicyclic hydrocarbon radical, amino, heterocyclyl radical in which 1 to about 4 heteroatoms are independently selected from oxygen, nitrogen and sulfur, wherein all said radicals may optionally be substituted with hydrogen, cyano, lower alkyl, nitro, amino, alicyclic hydrocarbon radicals, or aromatic hydrocarbon radicals which may be optionally substituted with lower alkyl; X is lower alkyl radical, lower alkenyl radical, lower alkynyl radical, aromatic hydrocarbon radical, (CH2)mQ(CH2)n, where m=1-3, n=1-3, and Q is sulfur, sulfinyl, sulfonyl or oxygen, C=O, lower alkynyl radical, aromatic hydrocarbon radical, alicyclic hydrocarbon radical or heterocyclyl radicals in which 1 to about 4 heteroatoms are independently selected from oxygen, nitrogen and sulfur, wherein all said radicals are optionally substituted with hydrogen, halogen and lower alkyl; R1, R2, R3 and R4 are independently selected from the group consisting of hydrogen and lower alkyl; A is a lower alkyl radical wherein said radical is optionally substituted with hydrogen, lower alkyl, hydroxyl, lower alkoxy, alkoxycarbonyl, alkylaryloxy, thiol, lower thioalkoxy, thioalkylaryloxy, thioaryloxy, sulfinylalkyl, sulfinylalkylaryl, sulfinylaryl, sulfonylalkyl, sulfonylalkylaryl, sulfonylaryl, halogen, aromatic hydrocarbon radicals, or alicyclic hydrocarbon radicals; or A can be a direct bond to the remainder of the molecule; B is CH2R5 where R5 is amidine, guandine, sulfonamide, amino which may be optionally substituted with alkyl, alkylaryl or aryl radicals.

Method for catalyzing addition reaction of alkyne and carbodiimide

本发明涉及一种催化炔烃与碳化二亚胺加成反应的方法，包括以下步骤：将式(1)所示的炔烃和式(2)所示的N,N’‑二异丙基碳化二亚胺在碱金属盐的催化作用下，在非质子溶剂二甲亚砜中于40‑60℃下进行反应；其中，式(1)和式(2)的结构式如下： 其中，R选自碳原子数为4‑7的芳香基。本发明提供了一种有效催化炔烃与碳化二亚胺加成反应生成脒类化合物的方法，催化剂简单易得，操作简便，反应条件较为温和，产率较高。

Process for the preparation of iminodiacetonitrile and iminodiacetic acid

An improved process is provided for produc-ing iminodiacetonitrile by contacting ammonia, formal-dehyde and hydrogen cyanide, or hexamethylenetetramine, formaldehyde and hydrogen cyanide in a reaction medium, the improvement which comprises the further steps of thereafter adjusting the pH of the reaction medium to a pH between about 5.5 and about pH 10 and heating the reaction medium to an elevated temperature for a sufficient time to convert by-products in the reaction medium to iminodiacetonitrile.

Method for preparing azoiminoethers and azocarboxylic acid esters and novel azocarboxylic acid mixed esters

The invention concerns a method for preparing an azoiminoether hydrochloride which consists in reacting an azonitrile with an alcohol and hydrochloric acid in an aromatic solvent, wherein the molar ratio R = HCl/azonitrile is > 2 when the alcohol is methanol and > 3 when the alcohol is ethanol or a higher alcohol. The invention also concerns a method for preparing an azocarboxylic acid ester which consists in the synthesis of an azoiminoether hydrochloride by the inventive method and, hydrolysis in the presence of the resulting azoiminoether hydrochloride. Said methods enable to obtain liquid composition of azocarboxylic acid esters. The invention further concerns mixed azoiminoether salts of formula (II'). The invention also concerns mixed azoiminocarboxylic acid esters corresponding to the formula (III').

N n-dimethyl-n'-(2 5-dimethylbenzyl) formamidine

THE PRESENT INVENTION RELATES TO NEW AMIDINE OF THE FORMULA R1-N=CH-N(-R3)-R2 OR AN ACID ADDITION SALT THEREOF, WHEREIN R1 REPRESENTS AN ALIPHATIC CYCLOALIPHATIC, CYCLOALOPHATIC-ALIPHATIC OR ARALIPHATIC RADICAL, R2 REPRESENTS A HYDROGEN ATOM OR A LOWER ALIPHATIC RADICAL AND R3 REPRESENTS A LOWER ALIPHATIC RADICAL, OR WHEREIN R2 AND R3 TOGETHER WITH THE NITROGEN ATOM TO WHICH THEY ARE BONDED REPRESENT A 5-MEMBERED TO 7MEMBERED HETEROCYCLIC STRUCTURE OPTIONALLY CONTAINING FURTHER HETERO-ATOMS AS WELL AS TO PESTICIDAL PREPARATIONS, WHICH CONTAIN, AS ACTIVE INGREDIENT, AN AMIDINE AS DEFINED ABOVE.

High-quality two-dimensional or quasi-two-dimensional layered perovskite single crystal material and preparation thereof

本发明属于二维钙钛矿单晶材料领域，公开了一种高质量二维或准二维层状钙钛矿单晶材料及其制备，其通式为(L) 2 (A) n‑1 B n X 3n+1 ，其中，L为正丙基胺根离子(C 3 H 7 NH 3 + )、异丙基胺根离子(C 3 H 7 NH 3 + )、正丁基胺根离子(C 4 H 9 NH 3 + )、正戊基胺根离子(C 5 H 11 NH 3 + )、正己基胺根离子(C 6 H 13 NH 3 + )、苯甲基胺根离子(C 6 H 5 CH 2 NH 3 + )、苯乙基胺根离子(C 6 H 5 CH 2 CH 2 NH 3 + )中的至少一种。本发明通过对二维或准二维钙钛矿单晶材料的内部组成及细节结构进行改进，引入特定的L这一有机间隔离子，能够大大扩充ABX 3 型钙钛矿材料中A位离子的种类选择范围，克服容忍因子t的限制，大大丰富有机‑无机杂化钙钛矿材料的种类。

Process for the preparation of a new phenoxyacetamidine.

Process for the preparation of iminodiacetonitrile and iminodiacetic acid

An improved process is provided for producing iminodiacetonitrile by contacting ammonia, formaldehyde and hydrogen cyanide, or hexamethylenetetramine, formaldehyde and hydrogen cyanide in a reaction medium, the improvement which comprises the further steps of thereafter adjusting the pH of the reaction medium to a pH between about 5.5 and about pH 10 and heating the reaction medium to an elevated temperature for a sufficient time to convert by-products in the reaction medium to iminodiacetonitrile.

Method for preparing azoiminoethers and azocarboxylic acid esters and novel azocarboxylic acid mixed esters

The invention concerns a method for preparing an azoiminoether hydrochloride which consists in reacting an azonitrile with an alcohol and hydrochloric acid in an aromatic solvent, wherein the molar ratio R = HCl/azonitrile is > 2 when the alcohol is methanol and > 3 when the alcohol is ethanol or a higher alcohol. The invention also concerns a method for preparing an azocarboxylic acid ester which consists in the synthesis of an azoiminoether hydrochloride by the inventive method and, hydrolysis in the presence of the resulting azoiminoether hydrochloride. Said methods enable to obtain liquid composition of azocarboxylic acid esters. The invention further concerns mixed azoiminoether salts of formula (II'). The invention also concerns mixed azoiminocarboxylic acid esters corresponding to the formula (III').

A kind of synthetic method of thiazole carboxylic acid's class chemical intermediate key intermediate species

本发明涉及一种噻唑羧酸类化学中间体关键中间产物的合成方法，它包括：（a）将氰基甲酸乙酯、异丙醚和异丙醇进行混合，在惰性气体保护下降温至‑20℃~‑5℃；（b）将水、碳酸氢钠、冰和甲基叔丁基醚进行搅拌混合，加入所述中间体，保持水温低于0℃且pH为弱碱性以游离所述中间体；（c）将所述化合物2加入乙醇中，在惰性气体保护下用冰浴降温，加入氯化铵进行反应这样能够实现对5‑乙氧基‑1,2,4‑噻二唑‑3‑羧酸关键中间体的化学合成，具有较高的得率和纯度，有利于工业化批量生产。

PROCESS FOR THE PREPARATION OF 2-NAPHTHALENE-ETHANE-IMIDE-AMIDES DISUBSTITUTED ON NITROGEN ATOMS, AND INTERMEDIATE PRODUCTS FOR ITS IMPLEMENTATION

Procédé de préparation de 2-naphtalène-éthane-imide-amides disubstitués sur les atomes d'azote et de leurs sels. On convertit un nitrile répondant à la formule : Process for the preparation of 2-naphthalene-ethane-imide-amides disubstituted on nitrogen atoms and their salts. We convert a nitrile corresponding to the formula:

Method for the preparation of azoiminoethers and of azocarboxylic acid esters, and novel mixed esters of azocarboxylic acids

The invention concerns a method for preparing an azoiminoether hydrochloride which consists in reacting an azonitrile with an alcohol and hydrochloric acid in an aromatic solvent, wherein the molar ratio R = HCl/azonitrile is > 2 when the alcohol is methanol and > 3 when the alcohol is ethanol or a higher alcohol. The invention also concerns a method for preparing an azocarboxylic acid ester which consists in the synthesis of an azoiminoether hydrochloride by the inventive method and, hydrolysis in the presence of the resulting azoiminoether hydrochloride. Said methods enable to obtain liquid composition of azocarboxylic acid esters. The invention further concerns mixed azoiminoether salts of formula (II'). The invention also concerns mixed azoiminocarboxylic acid esters corresponding to the formula (III').

Patent JPS619944B2

Method for preparing nitrogen containing compounds

A synthesis method which comprises reacting NH group-containing compounds with thiocyanates, cyanamides, nitrites or esters in the presence of a silylating agent to synthesize the corresponding nitrogen-containing addition or substitution products. This method not only enables the direct and efficient synthesis of nitrogen-containing compounds including isothioureas, guanidines, amidines and amides, but it also has a wide range of applications and is suitable for large-scale synthesis.

Amidinate ligand containing chemical vapor deposition precursors

The present invention is directed to amidinate ligand containing precursors for use in chemical vapor deposition. More particularly, the present invention is directed to amidinate ligand containing precursors such as metalloamidinates as chemical vapor deposition precursors. Suitable precursors for chemical vapor deposition such as atmospheric pressure chemical vapor deposition (APCVD) of films of metals, metal oxides, and metal nitrides, in which the physical properties of the precursors (or films) may be controlled by modification of the precursor ligand array are provided.

PROCEDURE FOR THE PREPARATION OF 2-NAFTALENE ETHANIMIDAMIDE N, N'-DISSTITUTED AND INTERMEDIARIES USED THEREOF

Method for preparing azoiminoethers and azocarboxylic acid esters and novel azocarboxylic acid mixed esters

The invention concerns a method for preparing an azoiminoether hydrochloride which consists in reacting an azonitrile with an alcohol and hydrochloric acid in an aromatic solvent, wherein the molar ratio R=HCl/azonitrile is >2 when the alcohol is methanol and >3 when the alcohol is ethanol or a higher alcohol. The invention also concerns a method for preparing an azocarboxylic acid ester which consists in the synthesis of an azoiminoether hydrochloride by the inventive method and, hydrolysis in the presence of the resulting azoiminoether hydrochloride. Said methods enable to obtain liquid composition of azocarboxylic acid esters. The invention further concerns mixed azoiminoether salts of formula (II'). The invention also concerns mixed azoiminocarboxylic acid esters corresponding to the formula (III').

Substituted amidines having high binding to the sigma receptor and the use thereof

N,N'-disubstituted-amidines, e.g., of the formula ##STR1## wherein R, R' and R" are substituted or unsubstituted hydrocarbon and/or heterocyclic groups. Methods are provided for the treatment or prophylaxis of anxiety in an animal, for treating psychosis, and for treating hypertension by administering an effective amount of an N,N'-disubstituted amidine which, preferably, has a high affinity for the sigma receptor.

L-n?6 -(1-iminoethyl)lysine derivatives useful as nitric oxide synthase inhibitors

There are disclosed derivatives of L-N6-(1-iminoethyl)lysine of general formula (I), pharmaceutical compositions containing these compounds, and to their use in therapy, in particular their use as nitric oxide synthase inhibitors. Y is a hydrogen, lower alkyl radical, lower alkenyl radical, lower alkynyl radical, aromatic hydrocarbon radical, alicyclic hydrocarbon radical, amino, heterocyclyl radical in which 1 to about 4 heteroatoms are independently selected from oxygen, nitrogen and sulfur, wherein all said radicals may optionally be substituted with hydrogen, cyano, lower alkyl, nitro, amino, alicyclic hydrocarbon radicals, or aromatic hydrocarbon radicals which may be optionally substituted with lower alkyl; X is lower alkyl radical, lower alkenyl radical, lower alkynyl radical, aromatic hydrocarbon radical, (CH¿2?)mQ(CH2)n, where m=1-3, n=1-3, and Q is sulfur, sulfinyl, sulfonyl or oxygen, C=O, lower alkynyl radical, aromatic hydrocarbon radical, alicyclic hydrocarbon radical or heterocyclyl radicals in which 1 to about 4 heteroatoms are independently selected from oxygen, nitrogen and sulfur, wherein all said radicals are optionally substituted with hydrogen, halogen and lower alkyl; R?1, R2, R3 and R4¿ are independently selected from the group consisting of hydrogen and lower alkyl; A is a lower alkyl radical wherein said radical is optionally substituted with hydrogen, lower alkyl, hydroxyl, lower alkoxy, alkoxycarbonyl, alkylaryloxy, thiol, lower thioalkoxy, thioalkylaryloxy, thioaryloxy, sulfinylalkyl, sulfinylalkylaryl, sulfinylaryl, sulfonylalkyl, sulfonylalkylaryl, sulfonylaryl, halogen, aromatic hydrocarbon radicals, or alicyclic hydrocarbon radicals; or A can be a direct bond to the remainder of the molecule; B is CH¿2R?5 where R5 is amidine, guandine, sulfonamide, amino which may be optionally substituted with alkyl, alkylaryl or aryl radicals.

Metal complexes with n-aminoamidinate ligands

본 발명은, N-아미노아미디네이트 리간드들을 갖는 신규한 금속 착물들, 더욱 특히 N,N'-비스(디메틸아미노)아세트아미디네이트, N,N'-비스(디메틸아미노)포름아미디네이트, N-디메틸아미노아세트아미디네이트 또는 N-디메틸아미노-N'-이소프로필-아세트아미디네이트 리간드들을 갖는 금속 착물들에 관한 것이며, 또한 이들의 제조 및 용도에 관한 것이다. 상기 금속 착물들은 5-원 킬레이트 환을 특징으로 한다. 상기 금속 착물들은 PTE의 주족(main group)들로부터의 금속으로, 또한 탄탈(Ta), 철(Fe), 코발트(Co), 니켈(Ni), 구리(Cu) 또는 아연(Zn)과 같은 전이족 원소들, 및 팔라듐(Pd)과 같은 귀금속으로 형성된다. 본 발명의 착물들은 CVD, MO-CVD 및 ALD와 같은 기상 박막 공정에 의한 기능성 층들의 제조를 위한 전구체로서의 용도를 발견한다. 추가로, 이들은 올레핀 하이드로아민화를 위한 그리고 올레핀 중합을 위한 촉매로서 사용될 수 있다. The present invention relates to novel metal complexes having N-amino amino ligands, more particularly N, N'-bis (dimethylamino) acetamidinate, N, N'-bis (dimethylamino) formamidinate , N-dimethylaminoacetamidinate or N-dimethylamino-N'-isopropyl-acetamidate ligands, and to their manufacture and use. The metal complexes are characterized by a 5-membered chelate ring. The metal complexes are metals from the main groups of PTE and also metals such as tantalum (Ta), iron (Fe), cobalt (Co), nickel (Ni), copper (Cu) Bivalent elements, and noble metals such as palladium (Pd). The complexes of the present invention find use as precursors for the preparation of functional layers by vapor phase thin film processes such as CVD, MO-CVD and ALD. In addition, they can be used as catalysts for olefin hydroamineation and for olefin polymerization.

Reversible room-temperature ionic liquids

One aspect of the present invention relates to salts that are room-temperature ionic liquids (RTILs), methods of making them, and methods of using them in connection with temporary or permanent gas sequestration. Another aspect of the present invention relates to a class of solvents which can be transformed into RTILs by exposure to a gas, and methods of using them in connection with temporary or permanent gas sequestration.

L-N6-(1-iminoethyl)lysine derivatives useful as nitric oxide synthase inhibitors

There is disclosed a novel amino alcohol amine derivatives of L-N6-(1-iminoethyl)lysine, pharmaceutical compositions containing these novel compounds, and to their use in therapy, in particular their use as nitric oxide synthase inhibitors.

Copper (I) compounds useful as deposition precursors of copper thin films

Copper (I) amidinate precursors for forming copper thin films in the manufacture of semiconductor devices, and a method of depositing the copper (I) amidinate precursors on substrates using chemical vapor deposition or atomic layer deposition processes.

PROCESSES FOR THE PRODUCTION OF IMINODIACETONITRILE AND IMINOACETIC ACID OR ITS SALT OR DERIVATIVE THEREOF

Process for the preparation of pyrazine compounds

N-substituted phenylalkyl and thienyl-alkyl amidines,their preparation,and compositions containing them

Antiarrhythmic diarylamidines

Novel diarylamidines, and compositions and methods for treating cardiac arrhythmias in mammals utilizing the novel and related known diarylamidines of formula I, II, III and IV ##STR1##

Preparation of lanthanide-containing precursors and deposition of lanthanide-containing films

Methods and compositions for depositing rare earth metal-containing layers are described herein. In general, the disclosed methods deposit the precursor compounds comprising rare earth-containing compounds using deposition methods such as chemical vapor deposition or atomic layer deposition. The disclosed precursor compounds include a cyclopentadienyl ligand having at least one aliphatic group as a substituent and an amidine ligand.

Process for the preparation of 4(5)-amino-5(4) carboxamidoimidazoles and intermediates thereof

本发明涉及新的、高效的制备式(I)化合物的方法(其中R 1 、和R 2 各自独立地为氢原子、C1-C10的可有取代基的烷基、具有脂环骨架的C3-C14烃基等)。式(I)化合物可以通过使式(II)化合物和/或其盐在碱性水溶液中环化并水解制备。此外，式(II)化合物可以自工业生产中常用的二氨基顺丁烯二腈以高产率制备。

Substituted amidines having high binding to the sigma receptor and the use thereof

N,N'-disubstituted-amidines, e.g., of the formula ##STR1## wherein R, R' and R" are substituted or unsubstituted hydrocarbon and/or heterocyclic groups. Methods are provided for the treatment or prophylaxis of anxiety in an animal for treating psychosis, and for treating hypertension by administering an effective amount of an N,N'-disubstituted amidine which, preferably, has a high affinity for the sigma receptor.

Atomic layer deposition using metal amidinates

PROCESS FOR THE PREPARATION OF N, N'-DISUBSTITUTED 2-NAPHTHALENE-ETHANIMIDAMIDES AND THEIR INTERMEDIATES

Process for the preparation of n,n'-disubstituted 2 - naphta - leneethan - imidamides and intermediates used therein

Process for α -acetyl-gamma-butyrolactone sodium salt free acetamidine hydrochloride

本发明涉及维生素B合成中间物的技术领域，具体而言，涉及一种α‑乙酰基‑γ‑丁内酯钠盐游离盐酸乙脒工艺，包括以下步骤：α‑乙酰基‑γ‑丁内酯钠盐与盐酸乙脒反应，产物经分离得到乙脒和α‑乙酰基‑γ‑丁内酯。本发明中将现有α‑乙酰‑γ‑丁内酯合成步骤中的中间产物α‑乙酰基‑γ‑丁内酯钠盐与盐酸乙脒反应，α‑乙酰基‑γ‑丁内酯钠盐利用盐酸乙脒中配位的盐酸，实现了α‑乙酰基‑γ‑丁内酯钠盐生成α‑乙酰基‑γ‑丁内酯的同时，盐酸乙脒中去除盐酸生成乙脒，达到两者目标产物的同步生成，节约步骤，并且对环境友好，提高收益。

Bisaminophenyl-based curatives and amidine-based curatives and cure accelerators for perfluoroelastomeric compositions

Novel monoamidine, monoamidoxime and bisamidine curatives, co-curatives and cure accelerators are provided for use with perfluoroelastomeric compositions as well as novel synthesis methods for making monoamidine- and monoamidoxime-based curatives, co-curatives and cure accelerators. Also provided are diphenyl-based curatives, co-curatives and cure accelerators having sufficiently high molecular weight such that the melting temperature of the curatives, co-curatives and cure accelerators is no greater than about 240° C., and more preferably no greater than about 230° C.

L-n6-(1-iminoethyl)lysine derivatives useful as nitric oxide synthaseinhibitors

There is disclosed a novel amino alcohol amine derivatives of L-N6-(1-iminoethyl)lysine, pharmaceutical compositions containing these novel compounds, and to their use in therapy, in particular their use as nitric oxide synthase inhibitors.

Metal(iv) tetra-amidinate compounds and their use in vapor deposition

Atomic layer deposition using metal amidinates

Metal films are deposited with uniform thickness and excellent step coverage. Copper metal films were deposited on heated substrates by the reaction of alternating doses of copper(I) N,N′-diisopropylacetamidinate vapor and hydrogen gas. Cobalt metal films were deposited on heated substrates by the reaction of alternating doses of cobalt(II) bis(N,N′-diisopropylacetamidinate) vapor and hydrogen gas. Nitrides and oxides of these metals can be formed by replacing the hydrogen with ammonia or water vapor, respectively. The films have very uniform thickness and excellent step coverage in narrow holes. Suitable applications include electrical interconnects in microelectronics and magnetoresistant layers in magnetic information storage devices.

Metal(Ⅳ) TETRA-AMIDINATE COMPOUNDS AND THEIR USE IN VAPOR DEPOSITION

금속(IV) 테트라키스( N,N' -다이알킬아미디네이트)가 합성되었고 특징되었다. 예시적인 금속은 하프늄, 지르코늄, 탄탈륨, 니오븀, 텅스텐, 몰리브데늄, 주석 및 우라늄을 포함한다. 이들 화합물은 휘발성이고, 열안정성이 높으며 금속 및 이들의 산화물, 질화물 및 다른 화합물의 증착에 적절하다. Metal (IV) tetrakis ( N, N' -dialkylamidinate) was synthesized and characterized. Exemplary metals include hafnium, zirconium, tantalum, niobium, tungsten, molybdenum, tin, and uranium. These compounds are volatile, have high thermal stability, and are suitable for the deposition of metals and their oxides, nitrides and other compounds. 화학기상증착, 원자층증착, 열중량 분석, 염 복분해 반응, X-ray 결정학 Chemical vapor deposition, atomic layer deposition, thermogravimetric analysis, salt metathesis reaction, X-ray crystallography

一种盐酸乙脒的制备方法、装置及装置的使用方法

本发明涉及盐酸乙脒制备技术领域，尤其涉及一种盐酸乙脒的制备方法、装置及装置的使用方法，将中和好的含氯化铵的母液压入离心机，分离氯化铵；将离心好的母液进行浓缩处理；浓缩结束，准备放料到乙脒干燥机中进行减压蒸甲醇；将浓缩釜中的母液一次放入干燥机中，将甲醇抽出；同时开蒸汽加热，控制蒸汽压力；直到蒸不出甲醇为止；关干燥机蒸汽，同时开排气阀，关真空泵，换循环水降温，当料温降到35℃以下时，可以开出料阀门出料；将烘干好的盐酸乙脒从出料口产出到接料槽中，取样化验，合格装袋。氨化反应采用亚乙脒滴加至氨甲醇中，提高收率，甲醇回收套用,降低消耗，干燥机在盐酸乙脒中的利用，提高产能。

Compound, raw material for forming thin film, method for manufacturing thin film, and amidine compound

一种2-取代苯基-乙脒盐酸盐的制备方法

本发明公开了一种2‑取代苯基‑乙脒盐酸盐的制备方法。首先利用三甲基铝或氯化亚铜，与氯化铵制备路易斯酸中间体，取2‑取代苯基乙腈类与路易斯酸中间体进行反应，使用溶剂对路易斯酸进行淬灭和抽滤后，再使用溶剂对腈类溶解，剩余的不溶物即为2‑取代苯基‑乙脒盐酸盐。该方法是以氯化铵和合适的脂肪腈为反应物，利用路易斯酸为反应催化剂，再进一步经过分离、洗涤等后处理，得到对应的2‑取代苯基‑乙脒盐酸盐。该方法大大缩短了反应的时间，提高了反应的效率，整个反应的速率和收率得到显著提高。本发明效率高、应用前景广阔。

Verfahren zur herstellung von aziminoethern

一种镁配合物的制备方法

本发明涉及一种镁配合物的制备方法，属于化学合成技术领域。本发明的制备方法包括以下步骤：S1：保护气氛下，向脒类化合物中加入溶剂I，得到脒类化合物溶液；向格式试剂中加入溶剂II，得到格式试剂溶液；S2：于‑30℃至0℃下，向S1的脒类化合物溶液中滴入锂盐，搅拌反应得到反应液；S3：将S2的反应液加入到S1的格式试剂溶液中，搅拌反应后加入脒类化合物，搅拌反应得到混合液；S4：对S3的混合物进行多次减压精馏得到镁配合物。本发明采用的原料来源广泛便宜，以往的工艺是通过溴化镁来合成目标产品，此原料保存比较难，容易变质，本发明使用的是甲基溴化镁等格式试剂，价格便宜，且降低了危险原料的使用量。

Atomlagenabscheidung (ald) mit hilfe von metallamidinaten

Un processo per preparare 2-naftalenetanimidamidi n,n'-di-sostituite e intermedi usati in questo processo.

一种三苯双脒杂质的制备

本发明提供了一种三苯双脒杂质的制备，包括以下步骤：(1)粗品制备：对苯二甲醛与N'‑(4‑氨基苯基)‑N，N‑二甲基乙酰胺反应，降温过滤，滤液搅拌析晶，过滤得滤饼；此滤液减压浓缩后再进行过滤，得滤饼；(2)精制：合并两次所得滤饼，加入乙醚回流，热过滤，降温析晶，抽虑，得滤饼，滤饼用少量乙醚洗涤；干燥得单脒成品，含量≥95％；本发明具有以下优点：操作简单，科学合理。

주석 화합물, 박막 형성용 원료, 박막, 박막의 제조 방법 및 할로겐 화합물

하기 일반식 (1) 로 나타내는 주석 화합물이 제공된다. [화학식 1] (식 (1) 중, R 1 및 R 2 는, 각각 독립적으로, 탄소 원자수 1 ∼ 5 의 알킬기 또는 탄소 원자수 3 ∼ 12 의 알킬실릴기를 나타내고, R 3 및 R 4 는, 각각 독립적으로, 탄소 원자수 1 ∼ 5 의 알킬기를 나타내며, R 5 는, 수소 원자 또는 탄소 원자수 1 ∼ 5 의 알킬기를 나타낸다.)

N-terminal dimerization methods with bis-amindino acid-and bis-thioimidate derivatives

Verfahren zur herstellung von iminodiacetonitril

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Verfahren zur herstellung von pyrazinverbindungen

Verfahren für die herstellung von 4(5)-amino-5(4)-carboxamidoimidazolen und deren zwischenprodukte

금속(ⅳ) 테트라-아미디네이트 화합물 및 기상증착에서의 그의 용도

금속(IV) 테트라키스( N,N' -다이알킬아미디네이트)가 합성되었고 특징되었다. 예시적인 금속은 하프늄, 지르코늄, 탄탈륨, 니오븀, 텅스텐, 몰리브데늄, 주석 및 우라늄을 포함한다. 이들 화합물은 휘발성이고, 열안정성이 높으며 금속 및 이들의 산화물, 질화물 및 다른 화합물의 증착에 적절하다. 화학기상증착, 원자층증착, 열중량 분석, 염 복분해 반응, X-ray 결정학

一种低锂含量的脒基金属配合物的制备方法

本发明涉及一种低锂含量的脒基金属配合物的制备方法，属于化学合成技术领域。本发明的制备方法包括以下步骤，S1、保护气氛下，将钾源中加入溶剂，得到钾源溶液；S2、于‑78℃至‑30℃下，向S1所述的钾源溶液中滴加脒基类化合物，反应得到反应液；S3、于‑78℃至‑30℃下，向S2所述的反应液中加入金属卤化物，反应得到混合液；S4、对S3所述的混合液进行产物收集，得到所述的低锂含量的脒基金属配合物。本发明的制备方法以钾源代替有机锂试剂，从源头控制了产品金属锂杂质的引入，使得纯化难度和成本大幅度降低，有利于得到高纯度的ALD前驱体源产品，有利于通过原子层沉积技术生长纳米厚度的高质量的薄膜，符合ALD前驱体制备工艺的要求。

L-n6-(1-iminoethyl)-lysinderivate, die als stickoxid-synthaseinhibitoren nützlich sind

Tin compound, thin-film forming raw material, thin-film, method for producing thin-film, and halogen compound

Provided is a tin compound, which is represented by the following general formula (1): in the formula (1), R 1 and R 2 each independently represent an alkyl group having 1 to 5 carbon atoms or an alkylsilyl group having 3 to 12 carbon atoms, R 3 and R 4 each independently represent an alkyl group having 1 to 5 carbon atoms, and R 5 represents a hydrogen atom or an alkyl group having 1 to 5 carbon atoms.

一种镁配合物的制备方法

本发明涉及一种镁配合物的制备方法，属于化学合成技术领域。本发明的制备方法包括以下步骤：S1：保护气氛下，向脒类化合物中加入溶剂I，得到脒类化合物溶液；向格式试剂中加入溶剂II，得到格式试剂溶液；S2：于‑30℃至0℃下，向S1的脒类化合物溶液中滴入锂盐，搅拌反应得到反应液；S3：将S2的反应液加入到S1的格式试剂溶液中，搅拌反应后加入脒类化合物，搅拌反应得到混合液；S4：对S3的混合物进行多次减压精馏得到镁配合物。本发明采用的原料来源广泛便宜，以往的工艺是通过溴化镁来合成目标产品，此原料保存比较难，容易变质，本发明使用的是甲基溴化镁等格式试剂，价格便宜，且降低了危险原料的使用量。