25-04-2013 дата публикации
Номер: US20130102807A1
A process for preparing carboxylic acid derivatives of the formula H—(C═O)—R, R is ORor NRR, Ris optionally substituted C-C-alkyl, C-C-cycloalkyl, C-C-heterocyclyl, C-C-aryl or C-C-heteroaryl, substituents are C-C-alkyl, C-C-alkoxy, C-C-cycloalkyl or C-C-aryl; Rand Rare independently hydrogen or optionally substituted C-C-alkyl, C-Ccycloalkyl, C-C-heterocyclyl, C-C-aryl or C-C-heteroaryl, substituents are selected from the group consisting of C-C-alkyl, C-C-cycloalkyl and C-C-aryl or Rand Rtogether with the nitrogen atom form a five- or six-membered ring which optionally comprises one or more heteroatoms selected from O, S and N and bearing the substituent R, Ris hydrogen or C-C-alkyl; by reacting a reaction mixture comprising carbon dioxide, hydrogen and an alcohol of the formula R—OH or an amine of the formula NHRRin the presence of a catalyst comprising gold at a pressure from 0.2 to 30 MPa and a temperature from 20 to 200° C. in a hydrogenation reactor. 114.-. (canceled)15. A process for preparing carboxylic acid derivatives of the general formula (Ia){'br': None, 'H—(C═O)—R\u2003\u2003(Ia),'}where{'sup': 1', '2', '3, 'R is selected from the group consisting of ORand NRR, where'}{'sup': '1', 'sub': 1', '15', '5', '10', '5', '10', '5', '10', '5', '10, 'claim-text': {'sub': 1', '15', '1', '6', '5', '10', '5', '10, 'where the substituents are selected from the group consisting of C-C-alkyl, C-C-alkoxy, C-C-cycloalkyl and C-C-aryl;'}, 'Ris unsubstituted or at least monosubstituted C-C-alkyl, C-C-cycloalkyl, C-C-heterocyclyl, C-C-aryl or C-C-heteroaryl,'}{'sup': 2', '3, 'sub': 1', '15', '5', '10', '5', '10', '5', '10', '5', '10, 'claim-text': [{'sub': 1', '15', '5', '10', '5', '10, 'where the substituents are selected from the group consisting of C-C-alkyl, C-C-cycloalkyl and C-C-aryl'}, 'or', {'sup': 2', '3', '4, 'Rand Rtogether with the nitrogen atom form a five- or six-membered ring which optionally additionally comprises one or more heteroatoms selected from ...
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