АРОМАТИЧЕСКАЯ СУЛЬФОНГИДРОКСАМОВАЯ КИСЛОТА В КАЧЕСТВЕ ИНГИБИТОРА МЕТАЛЛОПРОТЕАЗ

Изобретение относится к области медицины и касается способа лечения заболеваний, связанных с патологической активностью матриксных металлопротеаз, с помощью соединений формулы I, соединений формулы I, а также способа получения указанных соединений. Изобретение повышает эффективность лечения. 25 с. и 111 з.п. ф-лы, 152 табл.

Способ получения производных 4-фенил-2-тио-6-оксогексагидропиримидина

Способ получения диглицидиловых производных N-гетероциклических соединений

Гербицидно-антидотная композиция

Изобретение относится к химическим средствам защиты растений ,в частности, к химическим средствам, снижающим фототоксическое действие гербицидов в отношении культурных растений. Цель изобретения - снижение повреждения кукурузы тиокарбаматными гербицидами. Согласно изобретению композиция на основе тиокарбаматного гербицида содержит антидот из расчета 0,048-1,66 ч на 1 ч гербицида. В качестве антидота используют соединения общей формулы R1R2CXR3(YR4), где X-O или N-фенил, N-хлорфенил Y-O, N-фенил, N-2,6-диметилфенил R1-водород, дихлорметил, бромметил, хлорметил, трихлорметил R2-водород, дихлорметил R3 и R4 каждый C1-C5, C8-C18-алкил, аллил, бензил, тетрагидрофурил, фурил, 2-хлорэтил, диметиламиноэтил или R3 и R4 вместе бис-метилен, 2-этилэтилен, метилэтил, метилпропилен, гликофурансилен. Ангидоты по изобретению при меньшей дозе обеспечивают равный или более высокий уровень защиты кукурузы от токсического воздействия тиокарбаматных гербицидов. 5 табл.

Nichtwandernde 1-Hydrocarbyloxy-gehinderte Amineverbindungen als Polymerstabilisatoren

Mercaptosäureester, Thioacetale, Sulfide und Disulfide von sterisch gehinderten Aminen mit 1-Hydrocarbyloxygruppe.

Improved dental therapeutic compositions

A dental preparation comprises a compound of formula where R represents an alkyl, hydroxy-tertiary butyl, butylamino-propyl or dicyclohexyl group and a compatible vehicle. The preparation may be in the form of a paste, powder or liquid dentifrice, mouthwash, chewing gum, tablet or troche. R may be isopropyl, secondary butyl, ethylhexyl, dodecly, tetradecyl and hexadecyl groups. A concentrate of the pyrimidine compound and a surface active agent (an ethanolamine salt or a sorbitan ether-ester) may be prepared and added to the vehicle. Water-soluble oxolates, e.g. sodium, potassium, ammonium or the urea salt, may also be present in addition to the conventional vehicle. Example 1 describes a paste dentifrice comprising 1:3 - di - (ethyl hexyl) - 5 - methyl - 5 - amino - hexahydropyrimidine and a complex sorbitol ether-ester dispersing agent in a paste comprising calcium sulphate, calcium phosphate, sodium lauryl-sulphoacetate, gum tragacanth, sodium saccharin, glycerine ...

IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS

Improvements in or relating to protecting fabrics

... 1 : 3-disubstituted - 5 - aminohexahydropyrimidines may be prepared by catalytic hydrogenation of the corresponding 1 : 3-disubstituted-5-nitro-hexahydropyrimidines in the liquid phase under pressure, as described in U.S.A. Specification 2,387,043. Numerous examples of such compounds are given.

Metalloproteinaise inhibitors pharmaceutical compositions containing them and their pharmaceeutical uses and methods and intermediates useful for their preparation

Polar-substituted hydrocarbons

Metalloproteinase inhibitors, pharmaceutical compositions containing them and their pharmaceutical uses, and methods and intermediates useful for their preparation.

The invention relates to compounds of formula (1) wherein: Z is O or S; V is a divalent radical which together wtih C* and N forms a ring having six ring atoms, where each of said ring atoms other than C* and N independently is unsubstituted or substituted by a suitable substituent, and at least one of said other ring atoms is a heteroatom selected from O, N and S and the remainder is carbon atoms; and Ar is an aryl or heteroaryl group; and pharmaceutically acceptable prodrugs, salts and solvates thereof. The invention further relates to pharmaceutically acceptable prodrugs, salts and solvates of these compounds. The invention also relates to methods of inhibiting the activity of metalloproteinases by administering a compound of formula (1)or a prodrug, salt or solvate therof. The invention further relates to pharmaceutical compositions comprising an effective amount of these compounds, prodrugs, salts, solvates.The invetion still further relates to methods and intermediates useful for ...

Metalloproteinase inhibitors, pharmaceutical compositisions containing them and their pharmaceutical uses, and methods and intermediates useful for their preparations.

The invention relates to compounds of formula (1)wherein: z is o or s; v is a divalent radical which together with c* and n forms a ring having six ring atoms, where each of said ring atoms other than c* and n independently is unsubstituted or substituted by a suitable substituent, and at least one of said other ring atoms is a heteroatom selected from o, n and s, and the remainder is carbon atoms; and ar is an aryl or heteroaryl group; and pharmaceutically acceptable prodrugs, salts and solvates thereof. The invention further relates to pharmaceutically acceptable prodrugs, salts and solvates of these compounds. The invention also relates to methods of inhibiting the activity of metalloproteinases by administering a compound of formula (1)or a prodrug, salt or solvate thereof. The invention further relates to pharmaceutical compositions comprising an effective amount of these compounds, prodrugs, salts and solvates. The invention still further relates to methods and intermediates useful ...

Stable polymorph of N-(3-Ethynylphenylamino) -6,7-bis(2-methoxyethoxy) -4- quinazolinamine hydrochloride, methods of production, and pharmaceutical uses thereof

Retroviral protease inhibitors.

The invention relates to certain retroviral protease inhibitors, ...

Polar-substituted hydrocarbons

Stable polymorph of n-(3-ethynylphenylamino)-6,7-bis (2-methoxyethoxy)-4-quinazolinamine hydrochloride methods of production and pharmaceutical uses thereof

Meta lopro ei na e inh bitor pharmaceutical compositions containing them and their pharmaceutical uses and methods and intermediates useful for their preparation

Metalloproteinaise inhibitors pharmaceutical compositions containing them and their pharmaceeutical uses and methods and intermediates useful for their preparation

New 2 (nitromethylene) - 1,3-diazacycloalcanes, insecticidal compositions the container and their use to fight against undesirable insects.

Metalloproteinase inhibitors pharmaceutical compositions containing them and their pharmaceutical uses and methods and intermediates useful for their preparation

Stable polymorph of n-(3-ethynylphenylamino)-6,7-bis (2-methoxyethoxy)-4-quinazolinamine hydrochloride methods of production and pharmaceutical uses thereof

Metalloproteinaise inhibitors pharmaceutical compositions containing them and their pharmaceeutical uses and methods and intermediates useful for their preparation

Meta lopro ei na e inh bitor pharmaceutical compositions containing them and their pharmaceutical uses and methods and intermediates useful for their preparation

Stable polymorph of n-(3-ethynylphenylamino)-6,7-bis (2-methoxyethoxy)-4-quinazolinamine hydrochloride methods of production and pharmaceutical uses thereof

VERFAHREN ZUR HERSTELLUNG NEUER SALZE DES 1,3- BIS-(BETA-AETHYLHEXYL)-5-AMINO-5-METHYL- HEXAHYDROPYRIMIDINS

STABLE POLYMORPH the n (3-EHYNYLPHENYLAMINO) - 6, 7-BIS (2-METHOXYETHOXY) - 4-CHINAZOLIN-HYDROCHLORI S, PROCEDURE FOR ITS PRODUCTION AND ITS PHARMACEUTICAL APPLICATION

USE FROM ANGIOTENSIN [...] ANTAGONISTS TO THE PRODUCTION OF A DRUG FOR THE TREATMENT OF HYPERURICEMIE

5-PHENYL-1,4,5,6-TETRAHYDROPYRIMIDINDERIVATE, PROCEDURE FOR the PRODUCTION AND USE IN DRUGS.

Procedure for the production of pure Hexetidin

PROCEDURE FOR THE PRODUCTION OF NEW FLUORALKOXYPHENYL SUBSTITUTING NITROGEN HETERO CYCLES AND YOUR SALTS

PROCEDURE FOR KRYOPROTEKTION OF CELLS

INTERMEDIATE PRODUCTS FOR THE PRODUCTION OF METALLPROTEINASEHEMMERN

PROCEDURE FOR THE INHIBITION OF EIF5A-BIOSYNTHESE

POLYMETHYLENEIMINE DERIVATIVES

THE PREPARATION OF A PHARMACEUTICAL COMPOSITION FOR OPHTHALMOLOGICAL USE USE OF HEXETIDINE OR ITS DERIVATIVES OR SALTS FOR

AMIDE DERIVATIVES

Indane

The invention relates to compounds of formula (I) wherein R, R, R, R, and q have the designations cited in patent claim 1. Said compounds can be used, inter alia, for the treatment of tumours.

FLUOROALKYXYPHENYL-SUBSTITUTED NITROGEN HETEROCYCLES

5-PHENYL-1,4,5,6-TETRAHYDROPYRIMIDINE DERIVATIVES

PREPARATION OF N,N'-DICARBOXYMETHYL-1,3- PROPANEDIAMINES

SALTS OF 1,3-BIS-(B-ETHYLHEXYL)-5-AMINO-5-METHYL-HEXAHYDROPYRIMIDINES, PROCESSES FOR UCING THESE SALTS AND THEIR USE ESPECIALLY IN COMPOSITIONS HAVING BACTERIOSTATIC ACTIVITY

NOVEL SALTS OF 1,3-BIS-(.beta.-ETHYLHEXYL)-5-AMINO-5-METHYL-HEXAHYDROPYRIMIDINE, PROCESSES FOR PRODUCING THESE SALTS AND THEIR USE ESPECIALLY IN COMPOSITIONS HAVING BACTERIOSTATIC ACTIVITY Novel salts of 1,3-bis-.beta.-ethylhexyl)-5-amino-5-methyl-hexahydropyrimidine (hexetidine) with substituted benzoic acids and processes of preparing these salts are described. These novel salts have useful bacteriostatic activity and show stability in storage. The invention accordingly comprises compositions containing the novel salts and having bacteriostatic activity. The salts are additionally useful for the purification of hexetidine contained in raw mixtures obtained from the synthesis of this compound.

SALTS OF 1,3-BIS-(B-ETHYLHEXYL)-5-AMINO-5-METHYL-HEXAHYDROPYRIMIDINES, PROCESSES FOR UCING THESE SALTS AND THEIR USE ESPECIALLY IN COMPOSITIONS HAVING BACTERIOSTATIC ACTIVITY

PROCESS FOR THE PREPARATION OF AN ALIPHATIC, CYCLOALIPHATIC, AND/OR ALIPHATIC-CYCLOALIPHATIC DI- AND/OR POLYURETHANE

SULFONAMIDE FIBRINOGEN RECEPTOR ANTAGONISTS

NON-MIGRATING 1-HYDROCARBYLOXY HINDERED AMINE COMPOUNDS AS POLYMER STABILIZERS

A-17521/1+2/CGC 1419 NON-MIGRATING 1-HYDROCARBYLOXY HINDERED AMINE COMPOUNDS AS POLYMER STABILIZERS 1-Hydrocarbyloxy substituted hindered amine compounds which also contain a reactive functional group such as hydroxy, amino, oxirane or carboxyl can be chemically attached to selected polymer substrates by condensation reactions to give polymers containing a chemically-bonded, non-migrating stabilizer having excellent stabilization efficacy for protecting said polymer substrate from the adverse effects of actinic light.

NOVEL BENZOYL GUANIDINES, THEIR PRODUCTION AND THEIR USE IN MEDICAMENTS

New compounds of general formula (I) are provided: (I) which can be prepared by a variety of methods. The compounds may be used in pharmaceutical compositions.

Verfahren zur Herstellung von härtbaren, höhermolekulare Reste aufweisenden Derivaten von Formaldehydkondensationsprodukten von mindestens 2 NH2-Gruppen enthaltenden Amino-1,3,5-triazinen

Verfahren zur Herstellung von härtbaren, höhermolekulare Reste aufweisenden Derivaten von Formaldehydkondensationsprodukten von mindestens 2 NH2-Gruppen enthaltenden Amino-1,3,5-triazinen

Composition dentaire

Verfahren zur Herstellung von N,N'-Disulfonyl-1,3-diazacycloalkanen

Verfahren zur Herstellung von reinem Hexetidin

Diglycidyl derivatives of n-heterocyclic cpds

DIGLYCIDYL DERIVATIVES OF N-HETEROCYCLIC CPDS. N1-. of the formula: (where X1, X2, Y1 and Y2 are H or CH3, Z is a nitrogen-free, divalent residue which completes a (substituted) heterocyclic ring with 5 or 6 atoms, and m and n are each integers 0-30, preferably 0-4, m + n being 1), are prepared by reacting a (di)alcohol of formula: with a (beta-methyl)epihalohydrin. The ethers (I) can be hardened by means of the usual hardeners for polyfunctional epoxy compounds or epoxy resins. The curable compositions can be used for cast or pressed articles, laminates, coatings or adhesives. They are liquids of relatively low viscosity, and can be used as reactive diluents for epoxy resins.

Verfahren zur Herstellung von Trioxan-Mischpolymerisaten

Verfahren zur Herstellung von stickstoffhaltigen Copolymeren des Formaldehyds

Diglycidyl derivatives of n-heterocyclic cpds

DIGLYCIDYL DERIVATIVES OF N-HETEROCYCLIC CPDS. N1-. of the formula: (where X1, X2, Y1 and Y2 are H or CH3, Z is a nitrogen-free, divalent residue which completes a (substituted) heterocyclic ring with 5 or 6 atoms, and m and n are each integers 0-30, preferably 0-4, m + n being 1), are prepared by reacting a (di)alcohol of formula: with a (beta-methyl)epihalohydrin. The ethers (I) can be hardened by means of the usual hardeners for polyfunctional epoxy compounds or epoxy resins. The curable compositions can be used for cast or pressed articles, laminates, coatings or adhesives. They are liquids of relatively low viscosity, and can be used as reactive diluents for epoxy resins.

Process for the preparation of novel salts of 1,3-bis(beta-ethyl-hexyl)-5-amino-5-methylhexahydropyrimidine

Pesticide containing 2-(nitromethylene)-1,3-diazacycloalkanes

[UNK]

PROCEDURE FOR the PRODUCTION OF 2-SUBSTITUIERTEN 5-NITROSO-4,6-DIAMINO-PYRIMIDINEN.

СПОСОБЫ И ПРОМЕЖУТОЧНЫЕ ПРОДУКТЫ, ПОЛЕЗНЫЕ ДЛЯ ПОЛУЧЕНИЯ АНТИФОЛАТОВ

Данное изобретение относится к промежуточным продуктам и способам, относящимся к ним и начинающимся с них, ряду производных пиримидина формулы (V) которые являются промежуточными продуктами для получения полезных антифолатных соединений или сами представляют собой полезные антифолатные соединения. Международная заявка была опубликована вместе с отчетом о международном поиске.

НОВЫЕ СУЛЬФОНИЛАМИДНЫЕ ПРОИЗВОДНЫЕ В КАЧЕСТВЕ АНТАГОНИСТОВ БРАДИКИНИНОВЫХ РЕЦЕПТОРОВ

Настоящее изобретение относится к новым сульфаниламидным производным формулы (I), где R1-R5 и Z соответствуют тому, как указано в формуле изобретения, и их оптическим антиподам, или рацематам, и/или солям, и/или гидратам, и/или сольватам, которые являются селективными антагонистами брадикинина В1, к способу получения таких соединений, к фармакологическим композициям, их содержащим, и к их применению в лечении и профилактике болевых и воспалительных состояний.

Стабильный полиморф гидрохлорида N-(3-этинилфениламино)-6,7-бис(2- метоксиэтокси)-4-хиназолинамина, способ его получения, фармацевтическая композиция и применение

... 1. Технический результат Усиление лечебных свойств и повышение стабильности. 2. Суть Гомогенный кристаллический В полиморфгидрохлорида N-(3-этинилфенил)-6,7-бис (2-метоксиэтокси)-4-хиназолинамина, характерные пики дифрактограммы порошка которого, выраженные в 2 тета градусах, составляют 6.26, 12.48, 13,39, 16.96, 20.20, 21.10, 22.98, 24.46, 25.14, и 26.91, содержащая его фармацевтическая композиция, способ получения и применение для лечения гиперпролиферационных нарушений. 3. Область применения Медицина. Пунк.: 12 незав. 50 зав. Фиг.: 4 ...

N-ALKYL-N'-POLY(OXYALKYL)HEXAHYDROPYRIMIDINE QUATENARY AMMONIUM SALTS AND USE THEREOF AS CORROSION INHIBITORS

NEW SULFONAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS

НОВЫЕ СУЛЬФОНИЛАМИДНЫЕ ПРОИЗВОДНЫЕ В КАЧЕСТВЕ БРАДИКИНИНОВЫХ АНТАГОНИСТОВ

Изобретение касается новых производных сульфаниламида формулы (I), в которой R1-R5 и Z имеют указанные в описании значения, их оптических антиподов, или рацематов, и/или солей, и/или гидратов, и/или сольватов, которые представляют собой селективные антагонисты брадикинина В1; также способу их получения, содержащих их фармакологических композиций, и их применению для предупреждения и терапии боли и воспалительных процессов. Пункты: 6 независ. 2 завис.

Process of pyrimidin purification

NEW SALTS OF 1,3-(A) (B-ETHYLHEXYL) - 5-AMINO-5-METHYL-HEXADYDROPYRIMIDINE, THEIR METHOD OF PREPARATION, AND THEIR THERAPEUTIC USE

Pharmaceutically pure hexetidine prepn. - from crude 1,3-bis-(beta-ethylhexyl)-5- amino-5-methyl-hexahydropyrimidine

A novel process for prepn of pure 1,3-bis-(beta-ethyl-hexyl) -5-amino-5-methyl-hexahydropyrimidine (I) from the corresp.5-nitro cpd. (II) comprises (i) treating a soln of (II) contg. impurities with naphthalene-1,5-disulphonic acid (III) (ii) separating the selectively pptd salt (IV), (iii) treating (IV) with alkali to give pure (II) and (iv) converting (II) conventionally to (I). The salt (IV), i.g. 1,3-bis-(beta-ethylhexyl)-5-nitro-5-methyl-hexahydropyrimidine-na- phthalene 1,5-disulphonate, is new. (I) known as 'hexetidine', has antimicrobial activity and is used as an antiseptic and insecticide. (IV) also has fungicide and bactericide props. (I) of pharmaceutical purity can be obtd from crude (70-80% pure) (II) which has been made by reacting 2-ethylhexylamine with HCHO then nitroethane.

Azo compounds with pyrimidine derivatives, their preparation and their use as dyes.

Azo compounds with pyrimidine derivatives, their preparation and their use as dyes.

Diamino pyridine derivatives and also dermatological manufacturing method thereof

composição antimicrobiana, método de preparação da composição, dispositivo médico e uso da composição

Inibidores de metaloproteinase composições farmacéuticas contendo os mesmos e seus usos farmacéuticos e métodos e intermediários úteis

MODULATION OF PHOSPHORYL TRANSFERASE ACTIVITY OF GLUTAMINE SYNTHETASE

Methods of screening and designing compounds as inhibitors of glutamine synthetase, including adenylylated glutamine synthetase, are provided herein. Compounds and compositions useful for the treatment, prevention, and/or amelioration of bacterial infections, including Mycobacterium tuberculosis, are also provided.

PIPERAZIDES OF SUBSTITUTED PHENYLALANINE DERIVATES AS THROMBIN INHIBITORS

D,L-, L- and D-phenylalanine piperazides of formula (I) defined in the claim have been discovered which are clotting or thrombin and/or trypsin inhibitors. The compounds are easily absorbed orally, intraduodenally and especially rectally and are only slightly toxic.

Cycloaminals and a process for their preparation

The present invention is concerned with a new class of compounds prepared by reacting cyclic aminals of the formula with polyisocyanates of the formula R5(NCO)m+n to yield and with this process for obtaining said compounds, as well as the use of such compounds in polyurethane chemistry. If such compounds are free of isocyanates (n=0) they are useful as latent cross-linkers or hardeners activatable by heat or moisture. If such compounds carry free isocyanate groups (n=1 or 2) there are useful as synthetic resin precursors. In the above formulae m represents an integer of from 1 to 3, and n represents 0, 1 or 2, and the sum of m+n is 2 or 3, R1 represents an aliphatic hydrocarbon group which is optionally cyano-substituted and which has from 1 to 6 carbon atoms, a cycloaliphatic hydrocarbon group having from 5-10 carbon atoms or an araliphatic hydrocarbon group having from 7-10 carbon atoms; R2 represents a divalent aliphatic hydrocarbon group having from 2 to 6 carbon atoms ...

Ruthenium complexes, process for preparation thereof, and processes for producing open-ring polymer of cycloolefins and hydrogenation products thereof by using the complex as catalyst

The present invention relates to ruthenium complex compound wherein a heteroatom-containing carbene compound having a six-membered ring structure is bonded to ruthenium and a process for the preparation thereof; a process for producing ring-opened cyclic olefin polymer by subjecting a cyclic olefin to ring-opening metathesis polymerization in the presence of such a ruthenium complex compound; and a process for producing hydrogenated product of ring-opened cyclic olefin polymers by hydrogenating the carbon-carbon double bonds of the above ring-opened polymers. The invention gives hydrogenated product of ring-opened cyclic olefin polymers having physical properties different from those of hydrogenated product of ring-opened polymers of the prior art. Particularly, the use of dicyclopentadiene can give a hydrogenated product of ring-opened cyclic olefin polymer excellent in heat resistance, and this product can be advantageously used as parts or formed products for medical appliances or electrical ...

Vaccines and methods for prevention and treatment of drug-resistant HIV-1 and hepatitis B virus

The present invention provides methods for lowering a viral load of a virus resistant to an antiviral drug by inducing cytotoxic T lymphocytes (CTL) to recognize a predetermined mutated epitope within a viral protein of the drug-resistant virus. CTLs are induced by immunizing a host with a peptide comprising the predetermined mutation. The immunostimulating peptide may be further improved by epitope-enhancement for inducing specific CTLs. The antiviral protection against drug-resistant virus shown by compositions of the present invention and mediated by human HLA-restricted CTL has not been previously achieved.

Amides of 4-oxo-5-amidohexanoic acid derivatives

The invention concerns novel amide derivatives of the formula: R1-Y-NR²-CHR3-X-CHR11-CHR4-CO-NR5-CR6R16-Q-R10 wherein R1, R², R3, R4, R5, R6, R10, R11 and R16 are various substituents defined hereinafter, Y is carbonyl, thiocarbonyl, sulphonyl or amido, X is carbonyl, hydroxymethylene, thiocarbonyl or oximinomethylene and a is carbonyl or methylene, or a salt thereof, which are inhibitors of angiotensin converting enzyme and may be used for example, in the treatment of hypertension. The invention also provides pharmaceutical compositions of and processes for the manufacture of the novel amide derivatives.

BIS(1-HYDROCARBYLOXY-2,2,6,6-TETRAMETHYLPIPERIDIN-4-YL)-AMINE DERIVATIVE AND STABILIZED COMPOSITION

NEW MATERIAL: A compound of formula (n is 1-4; R1 and R2 are C1-4 alkyl, or pentamethylene formed together; E is C1-18 alkyl, C5-12 cycloalkyl, C7-15 alalkyl, C7-10 aryl or the like; T is H, C2-20 alkanoyl, C7-11 aroyl, carbamoyl or the like when n=1, CO, divalent acyl of dicarboxylic acid or the like when n=2, trivalent acyl of tricarboxylic acid when n=3, and tetravalent acyl of the tetracarboxylic acid when n=4). EXAMPLE: N,N,N',N'-Tetrakis(1-octyloxy-2,2,6,6-tetramethylpiperidin-4-yl) sebacamide. USE: Stabilizer for protecting polymers from the deleterious effects of actinic light. PROCESS: For example, bis(2,2,6,6-tetramethyl piperidin-4-yl) amine is reacted with acid chloride or isocyanate, and N-hydrocarbyloxy group is introduced into the product to obtain the compound of general formula. COPYRIGHT: (C)1991,JPO ...

DIAZONIUM SALT COMPOUND AND PRODUCTION THEREOF

NEW MATERIAL:Diazonium salt compounds expressed by formulas I and II (R1 is alkyl, alkoxy, halogen or H; R2 is alkylene; m and n are 1W3; X is stabi lizing anion). EXAMPLE: N,N'-Bis(3-methoxyphenyl)piperazine-4',4"-didiazonium bistetrafluoro borate expressed by formula I and O,O'-bis(3-chlorophenyl)ethylene glycol-4',4"- didiazonium bistetrafluoroborate expressed by formula II. USE: Effective in detecting esterase or protease, especially leukocyte. Accurate detection of the leukocyte, etc., is required for diagnosing and treating diseases in the kidney and urogenital tracts, etc. PREPARATION: Compounds expressed by formulas III and IV are diazotized and treated with a stabilizing anion to afford the compounds expressed by formulas I and II. COPYRIGHT: (C)1989,JPO&Japio ...

ПРОИЗВОДНЫЕ N-АЛКИЛ-N'-ПОЛИ(ОКСИАЛКИЛ)ГЕКСАГИДРОПИРИМИДИНА И СПОСОБ ИХ ПОЛУЧЕНИЯ, ИНГИБИТОР КОРРОЗИИ, ПРИМЕНЯЕМЫЙ В УСТАНОВКАХ ДЛЯ ДОБЫЧИ И ПЕРЕРАБОТКИ НЕФТИ

Производные N-алкил-N'-поли(оксиалкил)гексагидропиримидина общей формулы I ,где R1 - алкильные группы - статистические смеси гомологов и изомеров со средним числом С-атомов, равным 1-30, R2 -Н или C1-C3-алкил А - 1,2-алкиленовые группы с 2-10 С-атомами, р - целое число от 3 до 50, получают оксиалкированием эпоксидами N-замещенных гексагидропиримидинов формулы II. Благодаря применению соединений формулы I достигается превосходное защитное от коррозидействие для эмульсий типа вода-в-масле. 3 с. и 5 з.п. ф-лы, 4 табл.

1,3-ДИГЕТЕРОЦИКЛИЧЕСКИЕ ИНГИБИТОРЫ МЕТАЛЛОПРОТЕАЗ

... 1. Соединение, имеющее структуру, соответствующую формуле (I) где R1 представляет Н; R2 представляет водород, алкил или ацил, Аr представляет СОR3 или SO2R4; и R3 представляет алкокси, арилокси, гетероарилокси, алкил, арил, гетероарил, гетероалкил, амино, алкиламино, диалкиламино, ариламино и алкилариламино; R4 представляет алкил, гетероалкил, арил или гетероарил, замещенные или незамещенные; Х представляет О, S, SO, SO2 или NR5, где R5 независимо выбран из водорода, алкила, гетероалкила, гетероарила, арила, SO2R6, COR7, CSR8, РО(R9)2 или может, необязательно, образовывать кольцо с Y или W; и R6 представляет алкил, арил, гетероарил, гетероалкил, амино, алкиламино, диалкиламино, ариламино, диариламино и алкилариламино; R7 представляет водород, алкокси, арилокси, гетероарилокси, алкил, арил, гетероарил, гетероалкил, амино, алкиламино, диалкиламино, ариламино и алкилариламино; R8 представляет алкил, арил, гетероарил, гетероалкил, амино, алкиламино, диалкиламино, ариламино, диариламино и алкилариламино ...

Способ получения 3,3-диметил-1-аренсульфонил-4-арилпиперазинов

Способ получения диглицидиловых эфиров

Способ непрерывного получения 2-оксо-4-метил-6-уреидогексагидропиримидина

Verfahren zur in vivo Gewinnung von Inhaltsstoffen aus Zellen

Detergent- or cleaning agent, useful e.g. in liquid or gel form for flushing toilets and hard surface cleaning, comprises cyclic aminal

Detergent- or cleaning agent (A) comprises cyclic aminal. Independent claims are included for: (1) a cosmetic agent for hair or skin treatment, comprising cyclic aminal; (2) use of cyclic aminal in liquid or solid detergent or cleaning agent; (3) a cyclic aminal with 6-8 cyclic structure; and (4) the preparation of cyclic aminal comprising mixing substituted alkylenediamine and aldehyde together in an organic solvent, preferably methanol.

HETEROCYCLIC MULTIFUNCTIONAL AMINE ADDUCTS AND CURABLE COMPOSITIONS CONTAINING THE SAME

HEXAHYDROPYRIMIDINE-1,3-DIACETONITRILE AND ITS 5-HYDROXY DERIVATIVE

BENZOYLGUANIDINE, YOUR PRODUCTION AND YOUR USE IN DRUGS

PROCEDURE FOR the PRODUCTION OF N1, N4 DIETHYLSPERMIN

ANTI-EOP READING TABLES, ANTIVIRAL ONES OR ANTIRETROVIRALE SPERMINDERIVATE

N-Alkyl-N'-Poly(Oxyalkyl)Hexahydropyrimidine-Quaternary Ammonium Salts And The Use Thereof As Corrosion Inhibitors

This invention relates to N-alkyl-N′-poly(oxyalkyl)hexapyrimidine-quaternary ammonium salts of the formulae (Ia)-(Ic) and mixtures thereof in which R 1 is C 8 -C 30 -alkyl or C 8 -C 30 -alkenyl, R 2 is hydrogen, C 1 -C 3 -alkyl, —COOH or a group selected from the formulae wherein the bonding occurs via the valence containing the B residue, B is a single bond or a C 1 to C 3 alkylene group R 3 is C 1 -C 4 -alkyl, vinyl or allyl, X − is methylsulfate or iodide, A is a 1,2-alkylene group having from 2 to 10 carbon atoms, and p is a number from 1 to 50.

CORROSION INHIBITOR WITH IMPROVED PERFORMANCE AT HIGH TEMPERATURES

Compositions may include a corrosion inhibitor including a heterocyclic diamine prepared from the reaction of an alkyl diamine and an aldehyde, wherein the alkyl diamine has the general formula: R4NH(CH)NHR5, where n is an integer between 3 and 6, and R4 and R5 are independently hydrogen or a C2-C30 saturated or unsaturated hydrocarbon radical. Methods may include contacting a metal surface with a corrosion inhibitor composition, wherein the corrosion inhibitor includes a heterocyclic diamine corrosion inhibitor from the reaction of an alkyl diamine and an aldehyde, wherein the alkyl diamine has the general formula: R4NH(CH)NHR5, where n is an integer between 3 and 6, and R4 and R5 are independently hydrogen or a C2-C30 saturated or unsaturated hydrocarbon radical. 1. A composition , comprising: [{'br': None, 'sub': 2', 'n, 'R4NH(CH)NHR5'}, 'wherein n is an integer between 3 and 6, and R4 and R5 are independently hydrogen or a C2-C30 saturated or unsaturated hydrocarbon radical., 'a corrosion inhibitor comprising a heterocyclic diamine prepared from the reaction of an alkyl diamine and an aldehyde, wherein the alkyl diamine has the general formula3. The composition of claim 1 , wherein the aldehyde is one or more selected from a group consisting of formaldehyde claim 1 , 2-hydroxynapthaldehyde claim 1 , 7-phenyl-2 claim 1 ,4 claim 1 ,6-heptatrienal claim 1 , crotonaldehyde claim 1 , 2-hexenal claim 1 , 2-heptenal claim 1 , 2-octenal claim 1 , 2-nonenal claim 1 , 2-decenal claim 1 , 2-undecenal claim 1 , 2-dodecenal claim 1 , 2 claim 1 ,4-hexadienal claim 1 , 2 claim 1 ,4-heptadienal claim 1 , 2 claim 1 ,4-octadienal claim 1 , 2 claim 1 ,4-nonadienal claim 1 , 2 claim 1 ,4-decadienal claim 1 , 2 claim 1 ,4-undecadienal claim 1 , 2 claim 1 ,4-dodecadienal claim 1 , 2 claim 1 ,6-dodecadienal claim 1 , citral claim 1 , 1-formyl-[2-(2-methylvinyl)]-2-n-octylethylene claim 1 , cinnamaldehyde claim 1 , dicinnamaldehyde claim 1 , p-hydroxycinnamaldehyde claim 1 , p-methyl ...

CYCLOAMINALE, A PROCESS FOR THEIR MANUFACTURING AND THEIR USE

Method for producing organic nitro compounds

FIELD: chemistry. SUBSTANCE: invention relates to the organic nitro compound chemistry and specifically to a process for producing nitro compounds of the general formula of RNO 2 , where R=n-C 4 H 9 O-; O 2 NO(CH 2 ) 2 O-; O 2 NO(CH 2 ) 2 O(CH 2 ) 2 O-; O 2 NOCH 2 CH(ONO 2 )CH 2 O-; (O 2 NOCH 2 ) 3 CCH 2 O-; where m=1, 2; where n=2, 3; , which can find application in producing high-energy products, medicines, dyes, polymers, etc. The method consists in the fact that the corresponding alcohols or amines derivatives are subject to nitration with nitric oxide (V) or its mixture with 100% nitric acid in a medium of lower hydrofluorocarbons, the process is carried out at a pressure of 3-60 bar and a temperature of 5-40°C at a molar ratio of the corresponding starter compound and nitrating agent 1:(1.1-4.4). EFFECT: method allows to reduce fire and explosion hazard of the process, improve its environmental performance and obtain the desired compounds with high output. 2 cl, 20 ex РОССИЙСКАЯ ФЕДЕРАЦИЯ ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ФОРМУЛА (21)(22) Заявка: (19) RU (51) МПК C07C 201/02 C07C 203/04 C07C 241/00 C07C 243/02 C07D 233/02 C07D 239/04 C07D 493/04 2016112861, 05.04.2016 05.04.2016 Дата регистрации: C1 (2006.01) (2006.01) (2006.01) (2006.01) (2006.01) (2006.01) (2006.01) (72) Автор(ы): Жарков Михаил Николаевич (RU), Кучуров Илья Григорьевич (RU), Фоменков Игорь Владимирович (RU), Злотин Сергей Григорьевич (RU) (73) Патентообладатель(и): Федеральное государственное бюджетное учреждение науки Институт органической химии им. Н.Д. Зелинского Российской академии наук (ИОХ РАН) (RU) Приоритет(ы): (22) Дата подачи заявки: 05.04.2016 (45) Опубликовано: 17.02.2017 Бюл. № 5 (56) Список документов, цитированных в отчете о поиске: I.V. KUCHUROV ET AL., Synthesis of nitric acid esters from alcohols in a dinitrogen pentoxide/carbon dioxide liquid system, MENDELEEV COMMUN., 2012, 22, pp.67-69. I.V. KUCHUROV ET AL., Nitration of carbonic, sulfuric and ...

Process for the preparation of nitrogenous copolymers of formaldehyde

Nitrogen and amino compounds and their preparation process

Use of certain trioxane copolymers for extrusion or deep drawing

Preparation of n,n'-dicarboxymethyl-1,3-propanediamines

PREPARATION OF N,N'-DICARBOXYMETHYL-1,3-PROPANEDIAMINES ABSTRACT OF THE INVENTION N,N'-Dicarboxymethyl-1,3-propanediamine (designated PDDA) is prepared by reacting 1,3-propanediamine with formaldehyde and HCN to form hexahydropyrimidine-1,3-diacetonitrile, which is hydrolyzed with an aqueous alkali metal hydroxide to form dialkali metal hexahydropyrimidine-1,3-diacetate which, in turn, is reacted with mineral acid to form the desired PDDA and formaldehyde. N,N'-Dicarboxymcthyl-2-hydroxy-1,3-propanediamine (designated HYDROXY-PDDA) is prepared by reacting 1,3-diamino-2-propanol with formaldehyde and HCN to form 5-hydroxyhexa-hydropyrimidine-1,3-diacetonitrile, which is hydrolyzed with an aqueous alkali metal hydroxide to form dialkali metal 5-hydroxyhexahydropyrimidine-1,3-diacetate which, in turn, is reacted with acid to form the desired HYDROXY-PDDA and formaldehyde.

Silyl-protected nitrogen-containing cyclic compounds and making method

本发明提供具有式(1)的甲硅烷基保护的含氮环状化合物，其中R 1 、R 2 和R 3 各自为单价烃基，R 4 和R 5 各自为二价烃基，R 6 、R 7 和R 8 各自为H或者单价烃基，A为-C(O)OR 9 或-C≡N，R 9 为单价烃基，并且a为0或1。该化合物添加到聚氨酯、聚酯或聚碳酸酯树脂以形成单组分型固化性组合物从而对其赋予刚度、机械强度和透明性。

Substituted 1,3-diaminopropanes

Hexetidine purificn - by conversion into the naphthalene -1,5-disulphonate salt

Purificn. of hexetidine by prepg. the naphthalene-1,5-disulphonate salt in a reaction medium in which the salt is insol., the pptd. salt being collected and converted into pure hexetidine by treating with an aq. alkali. The process is adapted for the industrial scale and gives pure hexetidine a known antibacterial, which cannot be freed from by-products by fractional distn. Suitable solvents are opt aq. lower alkanols, esp. aq. 60-70% isopropanol.

Method for the synthesis of rilpivirine intermediate

Process for purifying hexetidine

PREPARATION OF HEXAHYDROPYRIMIDINE SALTS

Equilibrated dynamic mixtures to control the release of perfuming aldehydes and ketones

Substituted 1,3-diaminopropanes

N min -Acyl-N-alkyl-1,3-diaminopropanes of formula R<1>CONH(CH2)3NHR<2> (where R<1> is R- or RNH where R is a substituted or unsubstituted hydrocarbon group and R<2> is alkyl) are prepared by selectively acylating N-alkyl-1,3-diaminopropanes. In the process a N-alkyl-1,3-aminopropane is reacted with an aldehyde to form a hexahydropyrimidine, the hexahydropyrimidine is acylated and the acylated hexahydropyrimidine is then hydrolysed to give the product.

Patent JPS5082081A

Silyl-protected nitrogen-containing cyclic compounds and making method

Silyl-protected nitrogen-containing cyclic compounds having formula (1) are provided wherein R 1 , R 2 and R 3 each are a monovalent hydrocarbon group, R 4 and R 5 each are a divalent hydrocarbon group, R 6 , R 7 and R 8 each are H or a monovalent hydrocarbon group. A is —C(O)OR 9 or —C≡N, R 9 is a monovalent hydrocarbon group, and a is 0 or 1. The compounds are added to polyurethane, polyester or polycarbonate resins to form one part type curable compositions for imparting stiffness, mechanical strength and transparency thereto.

Process for the production of bifunctional cosmid for cloning dna with actinomycetal origin

Antimicrobial agent hexetidine purificn. - by treating substd. benzoic acid salt with aq. base, extracting with water-immiscible organic solvent, and evaporating

In a new process for the prodn. of pure hexetidine (I) from its salts with acids of formula (II): (whre n is 1 or 2 and X is COOH, OH, NH2, SO3H or SO2NH2), the salt is introduced into an aq. soln. of a base the hexetidine thus released is extracted with a water-immiscible organic solvent; and the solvent is sepd. off, dried, and distilled off in vacuo under very mild conditions. Hexetidine is an antimicrobial agent used chiefly as an antiseptic for the oral mucous membranes. In an example, bis-hexetidine terephthalate (84.5g) is added to 1-N NaOG (3 l.), then 60-80 degrees petroleum ether (500 ml) is added and the mixt. is stirred until the salt has completely dissolved. The organic phase is sepd. off, dried, and evaporated in vacuo to give pure hexetidine (61g = ca 90% yield).

An improved rilpivirine process

Trisubstituted triazamacrocyclic compounds and their use as contrast agents

The present invention relates to a class of compounds and to diagnostic compositions containing such compounds where the compounds are iodine containing compounds. More specifically the iodine containing compounds are chemical compounds containing a saturated triaza cyclic central moiety containing carbonyl functions allowing for the arrangement of three iodinated phenyl groups bound thereto. The invention also relates to the use of such diagnostic compositions as contrast agents in diagnostic imaging and in particular in X-ray imaging and to contrast media containing such compounds.

Patent FR2295029B1

5-Phenyl-1,4,5,6-tetrahydropyrimidine derivatives, process of preparation and use in therapeutics

The present addition relates to 5-phenyl-1,4,5,6-tetrahydropyrimidine derivatives of formula in which X1 and 2, which are identical or different, each represent H, F, Cl, Br or CF3; and A represents a polyhydropyrimidinyl group of structure where Y represents H or OH; Ra represents a C1-C4 alkyl group or a C2-C5 alkanoyl group, it being possible for Ra to represent the hydrogen atom when at least one of the groups X1, X2 and Y is different from H; Rb represents a C1-C3 alkyl group; R<1>c and R<2>c, which are identical or different, each represent the hydrogen atom or a C1-C3 alkyl group; and to their addition salts as new industrial products. These new products are useful in therapeutics, especially as antidepressant agents and/or sedatives.

Substituted 1,3-diaminopropanes

ABSTRACT SUBSTITUTED 1,3-DIAMINOPROPANES N'-Acyl-N-alkyl-1,3-diaminopropanes of formula R1CONH(CH2)3NHR2 where R1 is R- or RNH where R is a substituted or unsubstituted hydrocarbon group and R2 is alkyl) are prepared by selectively acylating N-alkyl-1,3-diaminopropanes. In the process a N-alkyl 1,3-aminopropane is reacted with an aldebyde to form a hexahydropyrimidine, the hexahydropyrimidine is acylated and the acylated hexahydropyrimidine is then hydrolysed to give the product.

Textile protection process

1,3-Bis - (β-ethylhexyl) -5-amino-5-methyl-hexahydropyrimidine terephthalate, process for its preparation and pharmaceutical compositions containing it

Insensitive polynitramine compound

The energetic compound 2,4,8,10-tetranitro-2,4,8,10-tetraazaspiro [5.5]undecane(TNSU) is disclosed. A general method of making 1,3-dinitroso-1,3-diazacycloalkanes in a one pot synthesis by the condensation of the diamine and formaldehyde, followed by conversion to the nitroso compound with nitrous acid. The general method also provides for the production of the tetranitroso precusor of TNSU.

Patent FR2125207B1

Equilibrated dynamic mixtures to control the release of perfuming aldehydes and ketones

The present invention concerns a dynamic mixture obtained by combining, in the presence of water, at least one diamine derivative, comprising at least one heteroaryl moiety, with at least two perfuming aldehydes and/or ketones. The invention's mixture is capable of releasing in a controlled and prolonged manner said perfuming compounds, in particular perfuming ingredients, into the surrounding environment. The invention's dynamic mixture gives rise to a more evenly distributed positive effect for the release of the different carbonyl compounds which are part of the mixture than other examples reported in the prior art.

Process for the production of pure hexetidine

A PROCESS FOR PURIFYING HEXETIDINE IS DISCLOSED. THIS PROCESS COMPRISES FORMING THE SPARINGLY SOLUBLE 1,5-NAPHTHALENEDISLFONATE ACID SALT OF HEXETIDINE IN AN AQUEOUS ALIPHATIC ALCOHOL AND REGENERATING HEXETIDINE FROM SAID SALT BY TREATMENT WITH AN ALKALI.

Patent SU367602A3

Production of substituted derivatives of n, n'-methylenebis-(hexahydropyrimidines)

Equilibrated dynamic mixtures to control the release of perfuming aldehydes and ketones

The present invention concerns a dynamic mixture obtained by combining, in the presence of water, at least one diamine derivative, comprising at least one heteroaryl moiety, with at least two perfuming aldehydes and/or ketones. The invention's mixture is capable of releasing in a controlled and prolonged manner said perfuming compounds, in particular perfuming ingredients, into the surrounding environment. The invention's dynamic mixture gives rise to a more evenly distributed positive effect for the release of the different carbonyl compounds which are part of the mixture than other examples reported in the prior art.

Preparation of dialkali metal hexahydropyrimidine-1, 3-diacetate and dialkalimetal 5-hydroxyhexahydropyrimidine-1, 3-diacetate

PREPARATION OF DIALKALI METAL HEXAHYDROPYRIMIDINE-1,3-DIACETATE AND, DIALKALIMETAL 5-HYDROXYHEXAHYDROPYRIMIDINE-1,3-DIACETATE Abstract of the Disclosure or,

Ruthenium complexes, process for preparation thereof, and processes for producing open-ring polymer of cycloolefins and hydrogenation products thereof by using the complex as catalyst

The present invention relates to ruthenium complex compound wherein a heteroatom-containing carbene compound having a six-membered ring structure is bonded to ruthenium and a process for the preparation thereof; a process for producing ring-opened cyclic olefin polymer by subjecting a cyclic olefin to ring-opening metathesis polymerization in the presence of such a ruthenium complex compound; and a process for producing hydrogenated product of ring-opened cyclic olefin polymers by hydrogenating the carbon-carbon double bonds of the above ring-opened polymers. The invention gives hydrogenated product of ring-opened cyclic olefin polymers having physical properties different from those of hydrogenated product of ring-opened polymers of the prior art. Particularly, the use of dicyclopentadiene can give a hydrogenated product of ring-opened cyclic olefin polymer excellent in heat resistance, and this product can be advantageously used as parts or formed products for medical appliances or electrical components.

PREPARATION OF HEXAHYDROPYRIMIDINE SALTS

Process for purifying hexetidine

1,3-bis-(nitroalkyl) 5,5-di-nitrohexahydro pyrimidines

Linear N,N'-tetrasubstituted diamines and process for their preparation

This invention relates to the following compounds: ##STR1## Process for their preparation and uses thereof, where R 1 and R 2 are substituted groups, and R 6 , R 5 , R 4 and R 3 are hydrogen or substituted groups.

N-alkyl-n'-poly(oxyalkyl)hexahydropyrimidine-quatenary ammonium salts and the use thereof as corrosion inhibitors

This invention relates to N-alkyl-N'-poly(oxyalkyl)hexapyrimidine- quaternary ammonium salts of the formulae (la) - (lc) and mixtures thereof in which R 1 is C 8 -C 30 -alkyl or C 8 -C 30 -alkenyl, R 2 is hydrogen, C 1 -C 3 -alkyl, -COOH or a group selected from the formulae wherein the bonding occurs via the valence containing the B residue, B is a single bond or a C 1 to C 3 alkylene group R 3 is Ci-C4-alkyl, vinyl or allyl, X - is methylsulfate or iodide, A is a 1,2-alkylene group having from 2 to 10 carbon atoms, and p is a number from 1 to 50.

Четвертичные аммониевые соли n-алкил-n'-поли(оксиалкил)гексагидропиримидина и их применение в качестве ингибиторов коррозии

Настоящее изобретение относится к четвертичным аммониевым солям N-алкил-N'-поли(оксиалкил)гексагидропиримидина формул (Ia)-(Ic) и их смесям, в которых Rпредставляет собой C-C-алкил или C-C-алкенил, Rозначает водород, C-C-алкил, -COOH или группу, выбранную из формул (Id)-(Ig), в которых связывание происходит по валентным связям, содержащим остаток B, где B означает одинарную связь или C-C-алкиленовую группу, Rпредставляет собой C-C-алкил, винил, аллил или бензил, Xозначает метилсульфат или йодид, A представляет собой 1,2-алкиленовую группу, имеющую от 2 до 10 атомов углерода, и р означает число от 1 до 50.

sais de amônio quaternário de n-alquil-n'-poli(oxialquil)hexa-hidropirimidina e uso dos mesmos como inibidores da corrosão

resumo patente de invenção: "sais de amônio quaternário de n-alquil-n'-poli(oxialquil)hexa-hidropirimidina e uso dos mesmos como inibidores da corrosão". a presente invenção refere-se a sais de amônio quaternário de n-alquil-n'-poli(oxialquil)hexapirimidina das fórmulas (ia) - (ic) e suas misturas, nos quais r1 é c8-c30-alquila ou c8-c30-alquenila, r2 é hidrogênio, c1-c3-alquila, -cooh ou um grupo selecionado entre as fórmulas nas quais a ligação ocorre através da valência que contém o resíduo b, b é uma ligação simples ou um grupo c1 a c3-alquileno, r3 é c1-c4-alquila, vinila ou alila, x- é sulfato de metila ou idodeto, a é um grupo 1,2-alquileno que possui entre 2 a 10 átomos de carbono e p é um número entre 1 a 50. 1/1

Loro produzione e applicazione cicloamminali e procedimento per la

Novel process for preparing polyamine derivatives and intermediates thereof

Process for preparing polyamine derivatives and intermediates thereof

A process for preparing polyamines of the formula ##STR1## by selective introduction of the groups Z--CH 2 -- at the terminal nitrogens from a polyamine having no nitrogen substituents by formation of bis-hexahydropyrimidine derivative, acylation, reduction of acyl group to give Z--CH 2 --, and solvolysis.

Dérivés d'hexahydro pyrimidines et leur préparation

Hexahydro pyrimidine derivatives and process of making same

Verfahren zur herstellung von 1,3-bis- (beta-athylhexyl) -5-amino-5-methyl-hexahydropyrimidin

13-Bis(ß-äthylhexyl)-5-mtro-5-methylhexahydropyrimidin-naphthalin- 13-disulfonat, Verfahren zu seiner Herstellung und seine Verwendung zur Herstellung von reinem 13-Bis-(ß-äthylhexyl)-5-amino-5-methylhexanydropyrimidin

Werkwijze voor het bereiden van zeer zuiver 1,3-bis-((beta)-ethylhexyl)-4-amino-5-methylhexa- hydropyrimidine.

Nematozide Mittel

Sali di metalli alcalini e di metalli alcalino-terrosi di esaidropirimidina-1,3-diacetato e di 5-idrossiesaidropirimidina 1,3 diacetato e processo di loro preparazione

Preparation of dialkalimetal hexahydropyrimidine-1,3-diacetate and dialkalimetal 5-hydroxyhexahydropyrimidine-1,3-diacetate

Charge transfer complexes of tetrakisamino ethylenes

一种室温类离子液体及其制备方法和应用

本发明提供了一种室温类离子液体及其制备方法和应用，属于新材料技术领域。本发明提供的室温类离子液体为碳正阳离子的离子液体，结构新颖，其电导率在常规室温离子液体的电导率范围(100～1000μS·cm ‑1 )；同时本发明采用成本低且稳定性好的非质子极性溶剂作为吸收剂吸收含卤化氢气体，制得高附加值且室温下呈液态的类离子液体。本发明的制备方法简单，易于实现工业化应用，应用范围广泛，解决了现有工业应用中室温离子液体的使用种类简单且制备过程复杂的问题。

一种室温类离子液体及其制备方法和应用

本发明提供了一种室温类离子液体及其制备方法和应用，属于新材料技术领域。本发明提供的室温类离子液体为碳正阳离子的离子液体，结构新颖，其电导率在常规室温离子液体的电导率范围(100～1000μS·cm ‑1 )；同时本发明采用成本低且稳定性好的非质子极性溶剂作为吸收剂吸收含卤化氢气体，制得高附加值且室温下呈液态的类离子液体。本发明的制备方法简单，易于实现工业化应用，应用范围广泛，解决了现有工业应用中室温离子液体的使用种类简单且制备过程复杂的问题。