05-03-2015 дата публикации
Номер: US20150065490A1
Compounds of formula I 2. A compound according to claim 1 , in which{'sup': 1', '2', 'a, 'X is —R—Ar—Ror —R—Y;'}{'sub': 1', '10', '1', '10', '1', '10, 'Ar denotes a phenylene group optionally substituted by halo, C-C-alkyl, C-C-alkoxy or by C-C-alkoxy substituted by phenyl;'}{'sup': 1', '2, 'Rand Rare attached to adjacent carbon atoms in Ar, and'}{'sup': 1', '2, 'sub': 1', '10, 'either Ris C-C-alkylene and Ris hydrogen,'}{'sup': 1', '2, 'or Rand Rtogether with the carbon atoms in Ar to which they are attached denote a 5-, 6- or 7-membered cycloaliphatic ring;'}{'sup': 'a', 'sub': 1', '10', '6', '10', '7', '14, 'Ris a bond or C-C-alkylene optionally substituted by hydroxy, C-C-aryl or C-C-aralkyl; and'}{'sub': 1', '10', '1', '10', '2', '10', '3', '10', '1', '10', '3', '10', '7', '14', '7', '14', '6', '10', '1', '10', '1', '10', '6', '10', '1', '10', '3', '10', '6', '10', '1', '10', '1', '10', '1', '10', '6', '10', '7', '14', '1', '10', '1', '10', '1', '10', 'e', '1', '10', '6', '10', '1', '10', '6', '10', '7', '14', '1', '10', '3', '10', '6', '10, 'sup': b', 'c', 'b', 'c', 'b', 'd', 'e', 'd', 'e', 'e', 'f', 'f', 'g', 'g, 'Y is C-C-alkyl, C-C-alkoxy or C-C-alkynyl; C-C-cycloalkyl optionally fused to one or more benzene rings and optionally substituted by C-C-alkyl, C-C-cycloalkyl, C-C-aralkyl, C-C-aralkyloxy optionally substituted by halo, or by C-C-aryl optionally substituted by C-C-alkyl or C-C-alkoxy C-C-aryl optionally substituted by halo, hydroxy, C-C-alkyl, phenoxy, C-C-alkylthio, C-C-aryl, a 4- to 10-membered heterocyclic ring having at least one ring nitrogen atom, or by NRRwhere Rand Rare each independently C-C-alkyl optionally substituted by hydroxy or phenyl or Rmay additionally be hydrogen; phenoxy optionally substituted by C-C-alkoxy; a 4- to 10-membered heterocyclic ring having at least one ring nitrogen or oxygen atom, said heterocyclic ring being optionally substituted by C-C-alkyl, C-C-aryl, C-C-aralkyl, C-C-alkoxycarbonyl or by a 4- to 10-membered ...
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