Method for preparing a poly(ether sulfonimide or -amide) copolymer using cyclic oligomers

Disclosed is a method for preparing a poly(ethersulfonimide or ethersulfonamide) copolymer using cyclic oligomers, and more particularly, to a method for preparing a poly(ethersulfonimide or ethersulfonamide) copolymer by preparing a cyclic ether sulfone oligomer and a cyclic imide or amide oligomer and subjecting the cyclic ether sulfone oligomer and the cyclic imide or amide oligomer to ring-opening copolymerization in the presence of an alkali metal fluoride catalyst.

Co-Crystal Compound, Method for Preparing the Same and Oxidant of Gas Generator Propellant

A co-crystal compound containing ammonium nitrate and benzo-18-crown-6-ether. Ammonium nitrate and benzo-18-crown-6-ether are used to form the co-crystal compound with hydrogen bonding in a mole ratio of 1:1. A melting point of the co-crystal compound falls within a range of 124˜130° C., and the co-crystal compound can be prepared by an evaporation method or an anti-solvent method. The co-crystal compound comes with a non-hygroscopic property, a low burning rate (7 MPa, 0.58 mm/s) and a high pressure index (n>0.6), which can be used for replacing the oxidizer of a common gas generator propellant.

Novel Antischistosomal Agent

An object of the present invention is to provide a novel antischistosomal agent, and more specifically, to provide a novel drug capable of inhibiting a growth of schistosomes in vivo to prevent development of liver dysfunction due to eggs of the schistosomes in the case of infection with the schistosomes. The novel antischistosomal agent includes as an active ingredient a peroxide derivative. Specifically, the novel antischistosomal agent includes as an active ingredient a peroxide derivative represented by the general formula (I): 14-. (canceled)6. The method according to claim 5 , wherein the peroxide derivative is a compound represented by the general formula (I) wherein C represents a 4-tert-butylcyclohexylidene claim 5 , cyclododecylidene claim 5 , or adamantylidene group claim 5 , and n represents an integer of 1 to 4.9. The method according to claim 8 , which is used in such a manner that the peroxide derivative is administered two or four times a week at a dosage of 1 to 1 claim 8 ,000 mg on Weeks 2 and/or 5 after infection with schistosomes.10. The method according to claim 8 , which is used in such a manner that the peroxide derivative is administered two or four times at a dosage of 1 to 1 claim 8 ,000 mg on Week 5 after infection with schistosomes.11. The method according to claim 8 , wherein the peroxide derivative comprises a peroxide derivative represented by the general formula (I) claim 8 , wherein C represents a 4-tert-butylcyclohexylidene claim 8 , cyclododecylidene claim 8 , or adamantylidene group claim 8 , and n represents an integer of 1 to 4.13. The method according to claim 5 , wherein the antischistosomal agent further comprises olive oil.14. The method according to claim 13 , wherein the antischistosomal agent comprises the peroxide derivative in a blending ratio of 120 mg with respect to 2 ml of the olive oil.15schistosomiasisschistosomiasis.. The method of claim 5 , wherein said is urogenital16schistosomiasisschistosomiasis.. The method ...

METHOD FOR PREPARING 1,3,5-TRIOXANE

The present invention relates to a method for preparing 1,3,5-trioxane using a reaction distillation tower including a reactor and integrally formed distillation and extraction sections. Particularly, the present invention relates to a method for preparing 1,3,5-trioxane characterized in that the amount of formaldehyde discharged to the outside of the system is reduced, to thereby increase the yield of 1,3,5-trioxane by recirculating a portion of the water phase, which is discharged through the top of the reaction extraction tower, to the extraction section, and thus to the upper portion of the extractor supply stream which supplies extractant to the extraction section. 110202122222022. A method of preparing 1 ,3 ,5-trioxane using a reaction distillation tower including a reactor and a distillation tower provided with integrally-formed distillation and extraction units and , wherein , at the time of extracting 1 ,3 ,5-trioxane from the extraction unit , a part of a water phase , which is separated from a stream discharged from a top of the distillation tower , is refluxed to an upper end of an extractant supply stream of the extraction unit .220. The method of preparing 1 claim 1 ,3 claim 1 ,5-trioxane according to claim 1 , wherein the concentration of formaldehyde in the water phase separated from the stream discharged from the top of the distillation tower is 15 wt % or less. The present invention relates to a method of preparing 1,3,5-trioxane using a reaction distillation tower including a reactor and a distillation tower provided with a distillation unit and an extraction unit.Conventionally, 1,3,5-trioxane is obtained by the cyclization reaction of formaldehyde in the presence of an acid catalyst or a solid acid catalyst. A 1,3,5-trioxane-containing vapor obtained by the cyclization reaction is supplied from a reactor to a distillation tower. The 1,3,5-trioxane-containing vapor boiling in the distillation tower is concentrated and discharged, and then this ...

METHOD FOR PREPARING 1,3,5-TRIOXANE

The present invention relates to a method for preparing 1,3,5-trioxane using a distillation tower including a reactor, a distillation section, and an extraction section. Particularly, the present invention relates to a method for preparing 1,3,5-trioxane, in which the water phase separated from the stream discharged through the extraction unit of the reaction distillation tower is used in the process of extracting 1,3,5-trioxane. 110202122222122. A method of preparing 1 ,3 ,5-trioxane using a reaction distillation tower including a reactor and a distillation tower provided with a distillation unit and an extraction unit , wherein a water phase (a) , which is separated from a stream discharged from the extraction unit and then introduced into a decanter , is refluxed into the distillation unit and the extraction unit .22122. The method of preparing 1 claim 1 ,3 claim 1 ,5-trioxane according to claim 1 , wherein the water phase (a) is separated into a first water phase (a1) refluxed into the distillation unit and a second water phase (a2) refluxed into the extraction unit .320202220. The method of preparing 1 claim 2 ,3 claim 2 ,5-trioxane according to claim 2 , wherein a reflux ratio (f/e) of the water phase refluxed into the top of the distillation tower to the water phase discharged to the outside of the distillation tower is 1.0 or more claim 2 , and a reflux ratio (a2/f) of the second water phase (a2) refluxed into the extraction unit to the water phase refluxed into the top of the distillation tower is 2.0 or more.42220. The method of preparing 1 claim 1 ,3 claim 1 ,5-trioxane according to claim 1 , wherein the concentration of formaldehyde in the extraction unit of the distillation tower is 50 wt % or less. The present invention relates to a method of preparing 1,3,5-trioxane using a reaction distillation tower including a reactor and a distillation tower provided with a distillation unit and an extraction unit.Conventionally, 1,3,5-trioxane is obtained by the ...

CYCLIC CARBONATE MONOMERS AND RING OPENED POLYCARBONATES THEREFROM

Eight-membered ring cyclic carbonates having an oxygen or an acylated nitrogen at position 6 were prepared by reaction of precursor diols with ethyl chloroformate. The cyclic carbonates undergo organocatalyzed ring opening polymerization. In one instance, the initial polymer formed comprises a carbonate repeat unit having a Boc-protected nitrogen in the polymer backbone. Deprotecting the nitrogen with acid forms a cationic carbonate repeat unit having a positive charged secondary ammonium nitrogen in the polymer backbone. 2. The compound of claim 1 , wherein Ris selected from the group consisting of methyl claim 1 , ethyl claim 1 , n-propyl claim 1 , iso-propyl claim 1 , butyl claim 1 , sec-butyl claim 1 , t-butyl claim 1 , phenyl claim 1 , benzyl claim 1 , and allyl.3. The compound of claim 1 , wherein each R′ is selected from the group consisting of t-butyl claim 1 , ethyl claim 1 , and allyl.6. The method of claim 5 , wherein the solvent is tetrahydrofuran.7. The method of claim 5 , wherein the amine base is triethylamine.11. The method of claim 10 , wherein Ris selected from the group consisting of methyl claim 10 , ethyl claim 10 , n-propyl claim 10 , iso-propyl claim 10 , butyl claim 10 , sec-butyl claim 10 , t-butyl claim 10 , phenyl claim 10 , benzyl claim 10 , and allyl.12. The method of claim 10 , wherein R′ is selected from the group consisting of t-butyl claim 10 , ethyl claim 10 , and allyl.13. The method of claim 10 , wherein the polycarbonate comprises a residue of the initiator.18. The method of claim 17 , wherein the acid is trifluoroacetic acid.21. The compound of claim 20 , wherein Ris selected from the group consisting of methyl claim 20 , ethyl claim 20 , n-propyl claim 20 , iso-propyl claim 20 , butyl claim 20 , sec-butyl claim 20 , t-butyl claim 20 , phenyl claim 20 , benzyl claim 20 , and allyl.24. The polymer of claim 23 , wherein Ris selected from the group consisting of methyl claim 23 , ethyl claim 23 , n-propyl claim 23 , iso-propyl ...

COMPOUNDS AND METHODS FOR TREATING FIBROSIS OR CANCER

Provided herein, inter alia, are methods and compounds for treating a pulmonary disease, fibrosis, or cancer. 3. The compound of claim 1 , wherein Ris —NH claim 1 , —OH claim 1 , or substituted or unsubstituted heteroalkyl.4. (canceled)5. The compound of claim 1 , wherein Ris —NH claim 1 , —OH claim 1 , or substituted or unsubstituted heteroalkyl.6. (canceled)7. The compound of claim 1 , wherein Ris —NH claim 1 , —OH claim 1 , or substituted or unsubstituted heteroalkyl.8. (canceled)9. The compound of claim 1 , wherein Ris —NH claim 1 , —OH claim 1 , or substituted or unsubstituted heteroalkyl.10. (canceled)11. The compound of claim 1 , wherein Ris —NH claim 1 , —OH claim 1 , or substituted or unsubstituted heteroalkyl.12. (canceled)13. The compound of claim 1 , wherein Ris —NH claim 1 , —OH claim 1 , or substituted or unsubstituted heteroalkyl.14. (canceled)17. (canceled)18. (canceled)19. (canceled)20. The compound of claim 1 , wherein Ris independently —COOR claim 1 , —NRC(O)OR claim 1 , or —C(O)R.2128.-. (canceled)29. The compound of claim 1 , wherein Ris independently hydrogen.30. The compound of claim 1 , wherein Ris independently hydrogen.31. A pharmaceutical composition comprising the compound of and a pharmaceutically acceptable excipient.32. A method of reducing the level of activity of zinc finger protein Snail1 in a subject claim 1 , said method comprising administering an effective amount of a compound of to the subject.33. A method of reducing the level of activity of Lysyl oxidase homolog 2 (LOXL2) in a subject claim 1 , said method comprising administering an effective amount of a compound of to the subject.34. A method of inhibiting collagen cross-linking in a subject claim 1 , said method comprising administering an effective amount of a compound of to the subject.35. A method of treating fibrosis claim 1 , said method comprising administering to a subject in need thereof an effective amount of a compound of .36. (canceled)37. (canceled)38. A method ...

Use of Biomass to Produce Polyoxymethylene Copolymers

The present disclosure is directed to a process for producing a polyoxymethylene polymer or paraformaldehyde in an environmentally friendly and sustainable manner. The polyoxymethylene polymer or paraformaldehyde can be produced so as to be carbon neutral or even carbon negative. In one aspect, the polyoxymethylene polymer or paraformaldehyde is formed from a biogas or from a recycled gas. The biogas and the recycled gas are used to produce the components needed to form the polymer. 1. A process for producing a polyoxymethylene polymer comprising:forming a cyclic acetal from at least one carbon negative component comprising a biogas or a recycled gas;forming a comonomer from at least one carbon negative component; andpolymerizing the cyclic acetal with the comonomer in the presence of a catalyst to form a polyoxymethylene copolymer.2. A process as defined in claim 1 , wherein the process further comprises forming a chain transfer agent from at least one carbon negative component and polymerizing the cyclic acetal with the comonomer and the chain transfer agent in the presence of the catalyst to form the polyoxymethylene copolymer.3. A process as defined in claim 2 , wherein the at least one carbon negative component is used to form aqueous formaldehyde solutions for producing the cyclic acetal claim 2 , the comonomer and the chain transfer agent.4. A process as defined in claim 1 , wherein the carbon negative component is used to first form methanol.5. A process as defined in claim 1 , wherein the comonomer comprises dioxolane and wherein the polyoxymethylene copolymer contains 0.5 to 5 mol % comonomer.6. A process as defined in claim 2 , wherein the chain transfer agent comprises methylal or a glycol.7. A process as defined in claim 1 , wherein the chain transfer agent is used in an amount of 100 ppm to 1500 ppm claim 1 , based on the weight of the polyoxymethylene polymer.8. A process as defined in claim 1 , wherein the polyoxymethylene copolymer includes terminal ...

Solid-Liquid Process For Extraction Of Radionuclides From Waste Solutions

The invention related to a complexing system for extracting a radionuclide from a waste water solution including calix[n]arene groups on the surface of a porous conducting material. 1. A complexing system for extracting a radionuclide from a waste solution comprising calix[n]arene groups covalently bonded on the surface of a porous conducting material.2. The method of claim 1 , wherein the porous conducting material is a conducting-fiber material.3. The complexing system of claim 2 , wherein the conducting-fiber material is a carbon-fiber material.4. The complexing system of claim 3 , wherein the carbon-fiber material is selected from carbon felts.5. The complexing system of claim 1 , wherein the calix[n]arene groups are grafted on the surface of the porous conducting material.6. The complexing system of claim 1 , wherein the calix[n]arene groups are bonded or grafted via a covalent bond —C(═O)NH— claim 1 , —NH—C(═O)— claim 1 , or —C—C.7. The complexing system of claim 1 , wherein the calix[n]arene group is a calix[n]arene-crown ether group claim 1 , preferably a calix[4]arene-crown-6 ether group claim 1 , more preferably a 1 claim 1 ,3-alternate calix[4]arene-crown-6 conformer group.10. A complexing system obtainable according to .11. A compound of formula (Ia) or (Ib) as defined in .12. A method for extracting radionuclides from a waste solution claim 8 , said method comprising the step of:{'claim-ref': {'@idref': 'CLM-00001', 'claim 1'}, 'i) Contacting a volume of a waste solution with a complexing system according to ; optionally'}ii) Contacting the complexing system containing a portion of radionuclide obtained at step i), with a volume of a stripping solution in acidic conditions,thereby removing the complexed radionuclide from said complexing system into the stripping solution, to make the complexing system available for reuse ; and optionallyiii) Repeating steps i) and ii).13. The method of claim 12 , wherein the radionuclides are cesium and/or strontium.14. ...

NEW POLYMERS AND THE USE THEREOF FOR DETECTING ION FLUXES

Disclosed are ion-sensitive polymers and methods for their use for monitoring biological phenomena associated with ion fluxes, as well as organic electrochemical transistors including such polymers. 2. The method of claim 1 , wherein A is selected from the group consisting of styrene claim 1 , sulfonated styrene claim 1 , and 3 claim 1 ,4-ethylenedioxythiophene.3. The method of claim 1 , wherein the polymer comprising at least one unit of formula (I) is in the form of an ink.6. A method for detection of at least one flux of an ion selected from the group consisting of K claim 1 , Na claim 1 , Ca and Zn at the level of a cell or a set of cells claim 1 , comprising:{'claim-ref': {'@idref': 'CLM-00005', '#text': 'claim 5'}, '#text': 'providing the organic electrochemical transistor of ;'}exposing the cells to the organic electrochemical transistor; anddetecting the at least one flux of the selected ion.7. A method for detection of the presence and/or the quantification of at least one ion selected from the group consisting of K claim 1 , Na claim 1 , Ca and Zn in a liquid sample claim 1 , wherein the liquid sample is derived from a biological organism claim 1 , an environmental sample claim 1 , or sample collected during the monitoring of a chemical process claim 1 , comprising:{'claim-ref': {'@idref': 'CLM-00005', '#text': 'claim 5'}, '#text': 'providing the organic electrochemical transistor of ;'}exposing the liquid sample to the organic electrochemical transistor; anddetecting the presence and/or the quantification of the at least one selected ion.9. The polymer according to claim 8 , wherein the polymer is a copolymer further comprising at least one unit selected from the group consisting of EDOT units claim 8 , styrene(trifluoromethanesulfonyl)imide units claim 8 , styrene units claim 8 , sulfonated styrene units claim 8 , and units of formula (I) with A claim 8 , L and/or B different from those of the first unit of formula (I).10. The polymer according to claim ...

ORGANIC SOLAR CELL AND MANUFACTURING METHOD THEREFOR

The present specification relates to an organic solar cell and a method for manufacturing the same. 1. An organic solar cell comprising:a first electrode;a second electrode provided to face the first electrode;a photoactive layer provided between the first electrode and the second electrode; anda layer comprising a fullerene derivative provided to be in contact with the photoactive layer,wherein the fullerene derivative has a crown-type substituent.2. The organic solar cell of claim 1 , wherein the photoactive layer comprises a photoactive layer material comprising one or two or more materials selected from the group consisting of an electron acceptor material and an electron donor material claim 1 , andthe layer comprising the fullerene derivative is formed by a phase separation of the photoactive layer material and a material for the layer comprising a fullerene derivative.5. The organic solar cell of claim 3 , wherein L is a substituted or unsubstituted divalent ester group; a substituted or unsubstituted alkylene group; or a substituted or unsubstituted arylene group.6. The organic solar cell of claim 1 , further comprising an ionic group provided at a center of the crown-type substituent.7. The organic solar cell of claim 1 , wherein a content of the fullerene derivative having a crown-type substituent is 1 wt % to 15 wt % at an interface of the photoactive layer and the layer comprising a fullerene derivative.8. The organic solar cell of claim 1 , wherein the organic solar cell has an inverted structure in which the first electrode is a cathode and the second electrode is an anode.9. The organic solar cell of claim 1 , wherein the organic solar cell has a normal structure in which the first electrode is an anode and the second electrode is a cathode.10. The organic solar cell of claim 1 , wherein the organic solar cell further comprises an organic material having one or two or more layers selected from the group consisting of a hole injection layer claim 1 , a ...

Novel complexes for the separation of cations

Complexes including a solid support and a material with a matrix structure containing domains complexing rare earth or strategic metals, preparation process thereof and use thereof for extracting or separating the rare earth or strategic metals in an aqueous or organic medium.

PSEUDOROTAXANES, ROTAXANES AND CATENANES FORMED BY METAL IONS TEMPLATING

A pseudorotaxane, a rotaxane and a catenane are provided. The pseudorotaxane includes at least a macrocyclic host molecule, a guest molecule, and a metal ion. The host molecule contains at least a binding unit and an aromatic linking spacer. The guest molecule has at least a recognition unit. The metal ion is used to template the threading of the guest molecule through the macrocycle host molecule by coordinating to a binding pocket formed from the binding unit of the macrocycle and the recognition moiety of the guest molecule. Rotaxanes or catenanes can be synthesized from the pseudorotaxane complexes, with or without the metal template ion in their molecular structures. 1. A pseudorotaxane complex comprising:a host molecule having a macrocycle structure comprising at least a binding unit and an aromatic linking spacer, wherein the binding unit is oligo(ethylene glycol);a guest molecule having at least a recognition moiety, wherein the recognition moiety is a urea group, a carbamate group, an amide group, an oligo(ethylene glycol) group or a 2,6-bis(hydroxymethyl)pyridine group; anda metal ion, wherein the metal ion coordinates to the binding unit of the host molecule and the recognition moiety of the guest molecule.2. The pseudorotaxane complex of claim 1 , wherein the host molecule further comprises a binding assistant unit claim 1 , and the binding assistant unit is an oligo(ethylene glycol) group claim 1 , a 2 claim 1 ,6-bis(hydroxymethyl)pyridine claim 1 , a 2 claim 1 ,2′-oxy-di(ethanethiol) group claim 1 , a 1 claim 1 ,3-bis(iminomethyl)benzene group claim 1 , or a 2 claim 1 ,6-bis(iminomethyl)pyridine group.3. The pseudorotaxane complex of claim 1 , wherein the aromatic linking spacer is a p-xylenyl group or a 2 claim 1 ,6-lutidinyl group.5. The pseudorotaxane complex of claim 1 , wherein the guest molecule contains at least a glycine claim 1 , a repeating unit of kevlar claim 1 , or a repeating unit of nylon-6 claim 1 ,6.6. The pseudorotaxane complex of ...

Method of producing trioxane

Disclosed is a method of producing trioxane, including: (A) preparing trioxane from a high-concentration formaldehyde aqueous solution in the presence of an acid catalyst; (B) distilling a mixture including trioxane; (C) liquefying the distilled gas mixture; (D) mixing the liquefied liquid mixture with an extraction solvent and separating the mixture into an aqueous phase and a solvent phase; (E) distilling the solvent phase to give trioxane, and mixing the aqueous phase with the extraction solvent to give a mixture, which is then separated into an aqueous phase and a solvent phase; and (F) discharging the aqueous phase separated in (E) out of the system, and recirculating the solvent phase so as to be reused in (D) and (E).

FLUORESCENT PROBES FOR DETECTING HYDROGEN POLYSULFIDES

Reactive sulfur species have been recognized as an important regulator in redox biology, wherein the reactive sulfur species have been shown to be active in tumor suppressors, ion channels, and transcription factors. The disclosed invention is a novel composition of matter that allows for the detection of HS and HSspecies in living cells. These novel compositions represent significant progress in the field of chemical, HS and HSprobes as they have both been successfully applied in the visualization sulfur species in living systems. 4. A compound of claim 3 , wherein n=1 claim 3 , R is SH5. A compound of claim 3 , wherein n=1 claim 3 , R is S(CO)Rwherein Ris substituted alkyl6. A compound of claim 3 , wherein n=1 claim 3 , R is S(CO)Rwherein Ris substituted aryl10. A compound of claim 8 , wherein the linker is selected from the group consisting of piperazine cyclohexane-1 claim 8 ,4-diamine/4-aminopiperidine/1-(piperidin-4-yl)piperazine/[1 claim 8 ,4′-bipiperidin]-4-amine.11. A compound of claim 8 , wherein R is S(CO)Rand Ris aryl claim 8 , L is a piperazine and A is an azide.13. The method of claim 10 , wherein the HS and HSspecies are selected from the group consisting of persulfides claim 10 , hydrogen persulfides claim 10 , polysulfides claim 10 , and a protein bound elemental sulfur.14. The method of claim 10 , wherein the detecting step detects HS and HSspecies in a living system. The present application claims under 35 U.S.C. § 119, the priority benefit of U.S. Provisional Application No. 62/394,625 filed Sep. 14, 2016. The disclosure of the foregoing application is incorporated herein by reference in its entirety.This invention was made with government support under Grant/Contract No R01HL116571 awarded by the National Institutes of Health. The government has certain rights in the invention.This invention generally relates to fluorescent probes that take advantage of the reactivity of HS and HSspecies. These probes represent significant progress in the field, ...

Solid phosphoric acid catalyst, and method for producing trioxane

A solid phosphoric acid catalyst which, when gas-phase synthesizing trioxane from formaldehyde, results in production of trioxane at a high yield and at a high selection rate by markedly suppressing side reactions, reduces the adhesion of organic matter to the catalyst surface, and achieves a stable and long-term catalyst reaction. This solid phosphoric acid catalyst contains silicon phosphate oxide (SPO) obtained by sintering at a temperature of at least 200° C. a carrier material to which a phosphoric acid component has been added, and the total quantity of acid does not exceed 5 mmol per 1 g of solid phosphoric acid catalyst when calculated as acid quantity determined by NH 3 -TPD measurement.

THERAPEUTIC COMPOSITIONS

Compositions comprising ketone bodies and/or their metabolic precursors are provided that are suitable for administration to humans and animals and which have the properties of, inter alia, (i) increasing cardiac efficiency, particularly efficiency in use of glucose, (ii) for providing energy source, particularly in diabetes and insulin resistant states and (iii) treating disorders caused by damage to brain cells, particularly by retarding or preventing brain damage in memory associated brain areas such, as found in Alzheimer's and similar conditions. 131-. (canceled)32. A method of treating a patient for insulin insensitive diabetes comprising orally administering to that patient a therapeutically effective amount of a metabolic precursor of D-β-hydroxybutyric acid or acetoacetate , such as to elevate the patient's blood levels of ketone bodies , defined as the sum total of D-β-hydroxybutyric acid and acetoacetate , to from 0.3 mM to 20 mM ,{'sub': 1', '4, 'wherein the metabolic precursor is selected from the group consisting of esters of D-β-hydroxybutyric acid or its oligomers with alcohols selected from the group consisting of C-Calkyl alcohols, (R)-1,3-butandiol and glycerol.'}33. A method as claimed in wherein the metabolic precursor is an (R)-1 claim 32 ,3-butandiol ester.34. A method as claimed in wherein the patient is treated for Type II diabetes The present invention relates to compositions suitable for administration to humans and animals which have the properties of inter alia, (i) increasing cardiac efficiency, particularly efficiency in use of glucose, (ii) for providing energy source, particularly in diabetes and insulin resistant states and (iii) treating disorders caused by damage to brain cells, particularly by retarding or preventing brain damage in memory associated brain areas such as found in Alzheimer's and similar conditions. These compositions may be taken as nutritional aids, for example for athletes, or for the treatment of medical ...

RECEPTOR AND METHOD FOR REMOVING OXOANIONS FROM AQUEOUS PHASE

A receptor for the simultaneous removal of oxoanions and their counterions from aqueous phase, particularly containing radioactive wastes, containing amide groups specifically coordinating the oxoanions, as well as moieties specifically coordinating cations, according to the present invention is characterised in that it contains within one molecule domains binding oxoanions and domains binding cations, preferably adapting a molecular structure of a general formula: (I) wherein Z this is a group containing crown ether, preferably a benzocrown group, X is any substituent, including the Y-Z grouping, and Y is any substituent or 0 (i.e. a direct bond between N and Z), where the oxoanion binding domain is a squaramide unit coordinating the oxoanions through amide groups, and squaramide contains additional substituents that increase or decrease the acidity of its amide protons, compared to unsubstituted squaramide, whereas the counter ion binding domain is a crown ether of a size adjusted to the type of binding cation, which forms part of at least one of the aforementioned substituents of squaramide, where the receptor has the ability to remove oxoanions and their counterions from aqueous phase to another water-immiscible phase, preferably to organic phase, and has the ability to form soluble complexes in at least one of the aforementioned phases. The invention considers also a method of removing oxoanions in the form of inorganic salts from aqueous phase, using receptors of the invention in the form of organic molecules containing amide groups, according to the invention is characterised in that it uses the aforementioned receptors for simultaneous binding of oxoanions and their counterions in aqueous phase, preferably acidic when using the receptor with substituents increasing acidity of squaramide protons, or alkaline when using the receptor with substituents decreasing acidity of squaramide protons. A sensor for detecting oxoanions according to the invention is ...

Fullerene-containing hemicarceplexes and a method of purifying fullerenes by using the same

Fullerene⊙CTV complexes, comprising fullerene⊙CTV hemicarceplexes, formed by various cyclotriveratrylene (CTV)-based molecular cages and various fullerene guests are disclosed. A method of direct isolating at least a fullerene from fullerene mixtures by using the above fullerene CTV hemicarceplexes but without using crystallization or HPLC is also disclosed.

Light Activated Cation Separation

A method of separating one or more valuable metal cations from an ionic solution by (a) contacting the ionic solution with an activated photoisomerizable host molecule containing a photoisomerizable moiety and a host moiety, where the photoisomerizable moiety has first and second states, and where the host moiety has a greater affinity for a metal cation when the photoisomerizable moiety is in the first state (active binding state) than when the photoisomerizable moiety is in the second state (release state), so that an ion-host molecule association is formed, and (b) separating the ion-host molecule association from the ionic solution. Also disclosed are photoisomerizable host molecules, a method of recovering valuable metals from a waste stream using the photoisomerizable host molecules, and an apparatus comprising a photoisomerizable host molecule attached to a support. 1. A method of separating one or more metal cations from an ionic solution , the method comprising the steps of:(a) contacting said ionic solution with a photoisomerizable host molecule comprising a photoisomerizable moiety and a host moiety, wherein the photoisomerizable moiety has first and second states, and wherein the host moiety has a greater affinity for a metal cation when the photoisomerizable moiety is in the first state (active binding state) than when the photoisomerizable moiety is in the second state (release state), so that an ion-host molecule association is formed; and(b) separating said ion-host molecule association from said ionic solution.2. The method of claim 1 , further comprising the step of:(c) recovering the bound metal cation from said ion-host molecule association.3. The method of claim 2 , further comprising the step of:(d) recovering the photoisomerizable host molecule.5. The method of claim 4 , wherein claim 4 , when said photoisomerizable host molecule is in an active binding state configuration claim 4 , said host moieties selectively bind or bond one or more metal ...

TRIOXANE COMPOSITION AND METHOD FOR STORING SAME

The present invention provides a trioxane composition which comprises trioxane as a main component, an antioxidant, and at least one alkaline organic compound selected from the group consisting of an amine compound having an alcoholic hydroxy group in the molecule thereof, a thiocarbamate compound, and an organophosphorus compound, wherein the amount of the alkaline organic compound contained is 0.01 to 10 ppm, based on the trioxane, and wherein the trioxane composition is a liquid. 1. A polymerizable trioxane composition comprising trioxane as a main component , an antioxidant , and at least one alkaline organic compound selected from the group consisting of an amine compound having an alcoholic hydroxy group in the molecule thereof , a thiocarbamate compound , and an organophosphorus compound ,wherein the amount of the alkaline organic compound contained is 0.01 to 10 ppm, based on the trioxane, and wherein the trioxane composition is in a molten state.2. The trioxane composition according to claim 1 , wherein the alkaline organic compound is at least one compound selected from the group consisting of a tertiary amine compound having an alcoholic hydroxy group in the molecule thereof claim 1 , a dithiocarbamate compound claim 1 , and an alkyl- or arylphosphine compound.3. The trioxane composition according to claim 1 , wherein the alkaline organic compound is triethanolamine.4. The trioxane composition according to claim 1 , wherein the antioxidant is at least one compound selected from the group consisting of a phenolic compound and a hindered phenol compound; and wherein the amount of the antioxidant contained is 10 to 500 ppm claim 1 , based on the trioxane.5. The trioxane composition according to claim 1 , wherein the content of the trioxane in the trioxane composition is 95% or more.6. A polyacetal resin produced by polymerizing the trioxane composition according to .7. A polyacetal resin produced by polymerizing the trioxane composition according to .8. A ...

Process For The Production of Trioxane

The present invention relates to a process for producing cyclic acetal comprising i) preparing a liquid reaction mixture comprising a) formaldehyde source, b) an aprotic compound and c) a catalyst; and ii) converting the formaldehyde source into cyclic acetals. 1. A process for producing a cyclic acetal comprising:contacting a formaldehyde source with a liquid medium comprising a sulfur-containing organic compound in the presence of a catalyst; andat least partially converting the formaldehyde source into a cyclic acetal.2. (canceled)3. A process according to claim 1 , wherein the sulfur-containing organic compound has a boiling point of 140° C. or higher claim 1 , determined at 1 bar.4. (canceled)5. (canceled)6. A process according to wherein higher than 50% of the formaldehyde source is converted into one or more cyclic acetals during the reaction.7. A process according to wherein the liquid medium comprises at least 60 wt.-% claim 1 , of the sulfur-containing organic compound.8. A process according to claim 1 , wherein the sulfur-containing organic compound is selected from the group consisting of organic sulfoxides claim 1 , organic sulfones claim 1 , organic sulfonate esters claim 1 , and mixtures thereof.9. A process according to wherein the sulfur-containing organic compound is selected from the group consisting of cyclic or alicyclic organic sulfoxides claim 1 , alicyclic or cyclic sulfones claim 1 , and mixtures thereof.11. A process according to wherein the sulfur-containing organic compound is sulfolane.14. (canceled)15. A process according to wherein the formaldehyde source and the sulfur-containing organic compound form a homogeneous phase.16. (canceled)17. A process according to wherein the reaction produces trioxane and tetroxane.18. (canceled)19. A process according to wherein during the process a reaction mixture includes the formaldehyde source claim 1 , the sulfur-containing organic compound claim 1 , and the catalyst claim 1 , and wherein the ...

METHOD FOR PREPARING TRIOXANE

The present invention concerns a method for preparing 1,3,5-trioxane by trimerization of formaldehyde in the presence of methanesulfonic acid. The invention also concerns the use of at least one catalyst comprising methanesulfonic acid for the trimerization of formaldehyde into 1,3,5-trioxane. 1. A process for the trimerization of formaldehyde , said process comprising at least the following steps:1) bringing formaldehyde into contact with a catalyst comprising at least methanesulfonic acid;2) carrying out a reaction of trimerization of said formaldehyde into trioxane; and3) separating the trioxane from the reaction medium.2. The process as claimed in claim 1 , wherein the formaldehyde content ranges from 30% to 90% by weight claim 1 , relative to the total weight of the reaction mixture claim 1 , limits included.3. The process as claimed in claim 1 , wherein the content of methanesulfonic acid in anhydrous form or in an aqueous solution in the reaction mixture ranges from 0.1% to 25% by weight claim 1 , limits included claim 1 , of methanesulfonic acid expressed in anhydrous form claim 1 , relative to the total weight of the reaction mixture.4. The process as claimed in claim 1 , wherein the trimerization step 2) is carried out at a temperature ranging from 0° C. to 200° C.5. The process as claimed in claim 1 , wherein the formaldehyde trimerization reaction is carried out at a pressure set between 0.1·10Pa and 10·10Pa.6. The process as claimed in claim 1 , wherein the process is carried out continuously claim 1 , with continuous withdrawal of the trioxane formed.7. (canceled)8. The process as claimed in claim 1 , wherein the catalyst is methanesulfonic acid in an aqueous solution.9. (canceled)10. (canceled)11. The process as claimed in claim 1 , wherein the formaldehyde content ranges from 30% to 70% by weight relative to the total weight of the reaction mixture claim 1 , limits included.12. The process as claimed in claim 1 , wherein the formaldehyde content ...

Integrated Process for Producing Cyclic Acetals and Oxymethylene Polymers

A process for producing cyclic acetals is described. A formaldehyde source is contacted with an aprotic compound in the presence of a catalyst to produce the cyclic acetals. The aprotic compound can increase conversion rates and/or efficiency. In one embodiment, the formaldehyde source is obtained from methanol. In particular, methanol can be converted into formaldehyde which is then converted into a cyclic acetal. In one embodiment, the cyclic acetal can then be used to produce oxymethylene polymers. 1. A process for producing a cyclic acetal comprising:converting methanol to a formaldehyde;contacting the formaldehyde with a catalyst in the presence of an aprotic compound; andat least partly converting the formaldehyde to a cyclic acetal.2. (canceled)3. A process according to claim 1 , wherein the methanol is dehydrogenated in order to form the formaldehyde.4. A process according to claim 1 , wherein the formaldehyde is formed by nonoxidative dehydrogenation of methanol.5. A process according to claim 1 , wherein the formaldehyde is formed by dehydrogenating methanol at a temperature of from about 300° C. to about 1100° C.6. A process according to claim 1 , wherein the formaldehyde is formed in the presence of a catalyst comprising an alkali metal claim 1 , an alkaline earth metal claim 1 , copper claim 1 , zinc claim 1 , tin claim 1 , compounds thereof claim 1 , or mixtures thereof.7. A process according to claim 1 , wherein the formaldehyde is formed by extractive distillation.8. A process according to claim 1 , wherein the methanol is oxidized to form the formaldehyde.9. A process according to claim 7 , wherein the extractive distillation is carried out by feeding crude formaldehyde containing water and methanol to a middle or lower part of a distillation column and feeding an extractant to an upper part of the distillation column claim 7 , the extractant being inert to formaldehyde claim 7 , and wherein formaldehyde gas is collected from a top of the ...

METHOD FOR PURIFYING HALOGENATED OLIGOSILANES

1. The present invention relates to a method for the purification of halogenated oligosilanes as a pure compound or mixture of compounds each having at least one direct Si—Si bond, the substituents thereof being exclusively halogen or halogen and hydrogen, and the composition thereof being an atom ratio of substituent:silicon of at least 3:2, by the action of at least one purification agent on the halogenated oligosilane and isolation of the halogenated oligosilane with improved purity. 1. Method for the purification of halogenated oligosilanes SiXwith n=2 through n=6 as pure compounds or as mixtures of compounds in which the substituents X comprise chlorine or chlorine and hydrogen , characterized in that{'sup': '−', '(a) a fluoride is added to the halogenated oligosilane, wherein said fluoride is in pure form and/or as a fluoride mixture and/or as a fluorine-containing compound and/or preparation and added in an amount, when calculated as F in relation to the mass of the halogenated oligosilane, of more than 1 ppb, preferably more than 100 ppb, especially preferably more than 1 ppm, especially more than 10 ppm,'}(b) at least one processing phase takes place in which at least the fluoride acts upon the halogenated oligosilane, wherein the at least one processing is selected from a group comprising stirring, swirling, shaking, heating to reflux, diffusing, and passing through, preferably at least two processing phases comprising stirring and heating to reflux,(c) at least one separation method for the isolation of the halogenated oligosilane takes place, selected from a group comprising decanting, filtering, distilling, and subliming,(d) the halogenated oligosilane exhibits a reduced metal content after the purification.2. Method according to claim 1 , characterized in that the fluoride is selected from a group comprising alkali metal fluorides claim 1 , alkaline earth metal fluorides claim 1 , silicon fluorides SiXF(X=halogen claim 1 , organyl claim 1 , siloxanyl ...

Process For The Production Of Trioxane From Aqueous Formaldehyde Sources

The present invention relates to a process for producing cyclic acetal comprising i) preparing a liquid reaction mixture comprising a) a formaldehyde source, b) an aprotic compound and c) a catalyst; wherein the total amount of protic compounds is less than 40 wt.-%, based on the total weight of the reaction mixture; and ii) converting the formaldehyde source into cyclic acetals. 1. A process for producing a cyclic acetal comprising:reacting a formaldehyde source in the presence of a catalyst to produce a cyclic acetal, and wherein the reaction is carried out in a liquid medium comprising a liquid aprotic compound having a boiling point of 120° C. or higher determined at 1 bar, and wherein the amount of the liquid aprotic compound comprises at least 20 wt % of the liquid medium.2. (canceled)3. (canceled)4. (canceled)5. (canceled)6. A process according to claim 1 , wherein the formaldehyde source is an aqueous formaldehyde solution with a formaldehyde content ranging from about 60 to about 90 wt.-% claim 1 , based on the total weight of the aqueous formaldehyde solution.7. A process according to claim 1 , wherein the aprotic compound has a boiling point of 140° C. or higher claim 1 , determined at 1 bar and wherein the aprotic compound has a relative static permittivity of more than 15.8. (canceled)9. (canceled)10. A process according to wherein the liquid medium comprises at least 40 wt.-% claim 1 , of the aprotic compound.11. A process according to wherein the aprotic compound is selected from the group consisting of organic sulfoxides claim 1 , organic sulfones claim 1 , organic sulfonate esters claim 1 , and mixtures thereof.12. A process according to wherein the aprotic compound is selected from the group consisting of cyclic or alicyclic organic sulfoxides claim 1 , alicyclic or cyclic sulfones claim 1 , and mixtures thereof.14. A process according to wherein the aprotic compound is sulfolane.17. (canceled)18. (canceled)19. (canceled)20. A process according to ...

Process for Producing A Cyclic Acetal

The present invention relates to a process for producing cyclic acetal comprising i) preparing a reaction mixture comprising a) a formaldehyde source in a liquid medium and b) a catalyst; ii) converting the formaldehyde source into cyclic acetals, wherein the final conversion of said formaldehyde source to said cyclic acetal is greater than 10% on basis of the initial formaldehyde source. 1. A process for producing a cyclic acetal comprising:contacting gaseous formaldehyde with a liquid medium comprising a liquid aprotic compound in the presence of a catalyst; andat least partially converting the gaseous formaldehyde into a cyclic acetal.2. (canceled)3. A process according to claim 1 ,wherein the aprotic compound is a polar aprotic compound.4. (canceled)5. A process according to claim 1 , wherein the catalyst is heterogeneous with the liquid medium.6. A process according to claim 1 , wherein the weight ratio of gaseous formaldehyde to the aprotic compound is from about 1:50 to about 1:3.7. A process according to claim 1 , wherein the aprotic compound has a boiling point of 140° C. or higher determined at 1 bar.8. (canceled)9. A process according to wherein higher than 30% claim 1 , of the gaseous formaldehyde is converted into one or more cyclic acetals during the reaction.10. A process according to wherein the liquid medium comprises at least 60 wt.-% claim 1 , of the aprotic compound.11. A process according to wherein the aprotic compound is selected from the group consisting of organic sulfoxides claim 1 , organic sulfones claim 1 , organic sulfonate esters claim 1 , and mixtures thereof.12. A process according to wherein the aprotic compound is selected from the group consisting of cyclic or alicyclic organic sulfoxides claim 1 , alicyclic or cyclic sulfones claim 1 , and mixtures thereof.14. A process according to wherein the aprotic compound is sulfolane.17. (canceled)18. A process according to wherein the reaction is carried out at a temperature ranging from ...

Process for Recycling Polyacetals

A process for recycling polyoxymethylene polymers is disclosed. A polyoyxmethylene polymer is at least partially dissolved in an aprotic compound. The resulting solution or suspension (liquid mixture) is then contacted with a catalyst which causes the polyoxymethylene polymer to be converted into a cyclic acetal. The cyclic acetal can be separated, collected and used in other processes. In one embodiment, the cyclic acetal may be used to produce a polyoxymethylene polymer. 1. A process for the conversion of oxymethylene homo- or copolymers to cyclic acetals comprising the steps:a) at least partly dissolving an oxymethylene homo- or copolymer in a liquid medium comprising an aprotic compound andb) converting the at least partly dissolved oxymethylene homo- or copolymer in the presence of a catalyst to cyclic acetals.2. (canceled)3. (canceled)4. A process according to claim 1 , wherein at least 20 wt.-% claim 1 , of the oxymethylene homo- or copolymer is dissolved in the aprotic compound.5. A process according to wherein the oxymethylene polymer is at least partly dissolved at a temperature higher than 100° C.6. A process according to wherein the cyclic acetals obtained are purified or separated.7. A process according to wherein the aprotic compound is liquid under the dissolution condition.8. A process according to claim 1 , wherein the polyoxymethylene homo- or copolymer has a number average molecular weight (Mn) of more than 2 claim 1 ,000 Dalton.9. A process according to wherein the aprotic compound has a boiling point of 120° C. or higher claim 1 , determined at 1 bar.10. A process according to wherein the oxymethylene polymer claim 1 , the aprotic compound and the catalyst form a reaction mixture and wherein the reaction mixture comprises at least 60 wt.-% claim 1 , of the aprotic compound claim 1 , wherein the weight is based on the total weight of the reaction mixture.11. A process according to wherein the aprotic compound comprises a sulfur containing organic ...

Process for Producing A Cyclic Acetal In A Heterogeneous Reaction System

A process for producing a cyclic acetal is disclosed. According to the process, a formaldehyde source is combined with an aprotic compound and contacted with a heterogeneous catalyst which causes the formaldehyde source to convert into a cyclic acetal such as trioxane. The catalyst, for instance, may comprise a solid catalyst such as an ion exchange resin. In one embodiment, the process is used for converting anhydrous formaldehyde gas to trioxane. The anhydrous formaldehyde gas may be produced form an aqueous formaldehyde solution by an extractive distillation.

LITHIUM SELECTIVE CROWN ETHER,LITHIUM ADSORBENT USING SAME, AND PREPARATION METHOD THEREOF.

Disclosed herein are a novel crown ether with bulky and rigid groups and a method for preparing the same. Also provided are a lithium adsorbent comprising the novel crown ether immobilized onto a nanofiber, and a method for preparing the same. The lithium-selective crown ether is synthesized through intermolecular cyclization between a bulky epoxide and a rigid aromatic compound such as 1,2-dihydroxybenzene, and can effectively recover lithium ions. For use as a lithium adsorbent, the novel crown ether with both bulky and rigid subunits is immobilized onto a polymer nanofiber. The crown ether-immobilized polymer nanofibers may be formed into a recyclable membrane. 1. A method for preparing a lithium-selective crown ether comprising reacting by cyclization a bis-epoxide and a hydroxy benzene.2. The method of claim 1 , wherein the bis-epoxide is synthesized by reacting a diol with an allyl compound to give a dialkene compound (step a) and reacting the dialkene compound with a benzoic acid (step b).3. The method of claim 2 , wherein the diol is selected from the group consisting of pinacol claim 2 , 2 claim 2 ,2-diethyl-1 claim 2 ,3-propanediol claim 2 , [1 claim 2 ,1′-bicyclopentyl]-1 claim 2 ,1′-diol claim 2 , cis-1 claim 2 ,2-cyclohexanediol claim 2 , cis-1 claim 2 ,2-cyclopentanediol claim 2 , and a combination thereof.4. The method of claim 2 , wherein the allyl compound is allyl bromide.6. The method of claim 2 , wherein the benzoic acid is m-chlorobenzoic acid.8. The method of claim 1 , wherein the hydroxybenzene is 1 claim 1 ,2-dihydroxybenzene.9. The method of claim 1 , wherein the cyclization is carried out by reacting the bis-epoxide with the hydroxy benzene in presence of a metal hydroxide in a solvent.12. A method for preparing a lithium adsorbent using a crown ether claim 1 , comprising: mixing the crown ether and a polymer material in a solvent to give a dope solution (step a′); electrospinning the dope solution into polymer nanofibers (step b′); and ...

CHEMILUMINESCENT COMPOSITIONS, METHODS, ASSAYS AND KITS FOR OXIDATIVE ENZYMES

Chemiluminescent compositions, methods, assays and kits for oxidative enzymes are described. Further disclosed are dioxetane compounds of the form: 126.-. (canceled)28. The assay of claim 27 , for the detection of the change in oxidative enzyme activity in an enzyme inhibition or enzyme activation assay.29. The assay of claim 27 , for the detection of the presence of an oxidative enzyme in an enzyme induction or enzyme detection assay.30. The assay of claim 27 , for the detection of the presence of a CYP450 enzyme.3132.-. (canceled)33. The assay of claim 27 , comprising a dioxetane selected from the group consisting of AMPPD-Bn claim 27 , CDP-Star-Bn claim 27 , EG-Ad-Cl-Ph-OEOM claim 27 , EG-Ad-Ph-OBn claim 27 , bisCO2Me-Ad-Ph-OEOM claim 27 , Q+-Ad-Ph-OEt claim 27 , and Q+-Ad-Ph-OEOM claim 27 , and cytochrome 3A.34. The assay of claim 27 , comprising a dioxetane selected from the group consisting of AMPPD-Bn claim 27 , CDP-Star-Me claim 27 , CDP-Star-Et claim 27 , Cl-BZT-Me claim 27 , Cl-BZT-EOM claim 27 , BZT-Me claim 27 , and EG-Ad-Ph-OMe claim 27 , and cytochrome 2C19.3538.-. (canceled)39. The assay of claim 27 , comprising dioxetane Cl-BZT-Me claim 27 , and cytochrome 1A2.40. (canceled)41. The assay of claim 27 , comprising dioxetane Cl-BZT-EOM claim 27 , and cytochrome 3A5.42. The assay of claim 27 , comprising dioxetane Cl-BZT-EOM claim 27 , and cytochrome 2D6.43. (canceled)44. The assay of claim 27 , comprising dioxetane BZT-Me claim 27 , and cytochrome 2C9.4550.-. (canceled)51. The assay of claim 27 , comprising a dioxetane selected from the group consisting of bisCO2Na-Ad-Ph-OEt and bisCO2Na-Ad-Ph-OEOM claim 27 , and cytochrome 2C8.52. (canceled)53. The assay of claim 27 , conducted using a solid matrix.54. The assay of claim 27 , carried out in the further presence of a water-soluble enhancing substance that increases specific light energy production above that produced in its absence.55. The assay of claim 54 , wherein said water-soluble enhancing ...

ENERGY RECOVERY IN A METHOD FOR PREPARING 1,3,5-TRIOXANE

The present invention relates to a process for energy recovery in a process for the preparation of 1,3,5-trioxane. 115.-. (canceled)16. A process for energy recovery in a process for the preparation of 1 ,3 ,5-trioxane comprising the steps{'b': 1', '1', '1', '1', '1, 'a) reacting formaldehyde in the presence of water and at least one acidic catalyst in a first reactor (R) to obtain a first product mixture (P), which comprises water and 1,3,5-trioxane, wherein the first product mixture (P) is transferred as stream () from the first reactor (R) to a distillation tower (D),'}{'b': 1', '2', '2', '1', '1, 'b) contacting the first product mixture (P) with at least one extractant (E) in the distillation tower (D) to obtain an overhead product (OP), and a side cut (SC), wherein the overhead product (OP) comprises the at least one extractant (E) and water, and wherein the side cut (SC) comprises the at least one extractant (E) and 1,3,5-trioxane, wherein the overhead product (OP) is transferred as stream () from the distillation tower (D) to a mechanical compressor (MC), wherein the stream () has a first temperature (T) and a first pressure (p),'}{'b': 2', '3', '2', '2', '2', '3', '1', '2', '2', '3', '1', '2, 'c) mechanical compression of the stream () in the mechanical compressor (MC) to obtain a compressed stream (), which has a second temperature (T) and a second pressure (p), wherein the second temperature (T) of the compressed stream () is higher than the first temperature (T) of the stream () and wherein the second pressure (p) of the compressed stream () is higher than the first pressure (p) of the stream (),'}{'b': 3', '1, 'd) transferring heat from the compressed stream () to the first reactor (R).'}17. The process according to claim 16 , wherein step d) comprises the following steps{'b': 3', '1', '3, 'd1) transferring the compressed stream () from the mechanical compressor (MC) to a first heat exchanger (H) in which heat is transferred from the compressed stream () ...

NONAQUEOUS ELECTROLYTE SOLUTION AND ENERGY DEVICE USING SAME

The present invention provides an energy device having excellent properties. Also provided is a nonaqueous electrolyte solution containing a compound represented by the following Formula (1), wherein R, Rand Reach independently represent an organic group having 1 to 3 carbon atoms; and Rand R, Rand R, or Rand Rare optionally bound with each other to form a 5-membered ring or a 6-membered ring, with a proviso that a total number of carbon atoms of R, Rand Ris 7 or less. 2. The nonaqueous electrolyte solution according to claim 1 , wherein a total content of the compound represented by Formula (1) is 0.05 ppm by mass to 50 ppm by mass with respect to a total amount of the nonaqueous electrolyte solution.3. The nonaqueous electrolyte solution according to claim 1 , further comprising at least one compound selected from the group consisting of a fluorine atom-containing cyclic carbonate claim 1 , a carbon-carbon unsaturated bond-containing cyclic carbonate claim 1 , a difluorophosphate salt claim 1 , a fluorosulfate salt claim 1 , an isocyanate group-containing compound claim 1 , a cyano group-containing compound claim 1 , a cyclic sulfonate ester claim 1 , and a dicarboxylic acid complex salt.4. The nonaqueous electrolyte solution according to claim 1 , wherein claim 1 , in Formula (1) claim 1 , R claim 1 , Rand Rare each independently an organic group having 1 to 2 carbon atoms claim 1 , and the total number of carbon atoms of R claim 1 , Rand Ris 5 or less.5. An energy device claim 1 , comprising:plural electrodes capable of absorbing and releasing metal ions; anda nonaqueous electrolyte solution,{'claim-ref': {'@idref': 'CLM-00001', 'claim 1'}, 'wherein the nonaqueous electrolyte solution is the nonaqueous electrolyte solution according to .'}6. The energy device according to claim 5 , whereinthe plural electrodes capable of absorbing and releasing metal ions are a positive electrode capable of absorbing and releasing metal ions and a negative electrode capable of ...

CALIXCROWNS AND USES THEREOF

Provided herein are novel calixcrowns, such as those of Formula I, which are useful for coating a solid substrate such as a protein chip, diagnostic kit or protein separation pack. Also provided herein are methods detecting protein-protein interactions with a solid substrate coated with the calixcrown herein and an immobilized protein.

Process For Producing A Cyclic Acetal in a Heterogeneous Reaction System

A process for producing a cyclic acetal is disclosed. According to the process, a formaldehyde source is combined with an aprotic compound and contacted with a heterogeneous catalyst which causes the formaldehyde source to convert into a cyclic acetal such as trioxane. The catalyst, for instance, may comprise a solid catalyst such as an ion exchange resin. In one embodiment, the process is used for converting anhydrous formaldehyde gas to trioxane. The anhydrous formaldehyde gas may be produced form an aqueous formaldehyde solution by an extractive distillation. The aprotic compound and the formaldehyde solution may be extracted from the reaction product and recycled into the process. 1. A process for producing a cyclic acetal comprising:combining an aqueous formaldehyde solution with an aprotic solvent to form a reaction mixture, the aqueous formaldehyde solution containing formaldehyde in an amount greater than about 70% by weight;contacting the reaction mixture with a catalyst in a reactor under conditions that cause a portion of the formaldehyde to convert into a cyclic acetal to form a product stream, the product stream containing water, the cyclic acetal, unreacted formaldehyde, and the aprotic solvent; andfeeding the product stream to a low pressure separating device, the low pressure separating device producing a cyclic acetal-rich gas stream and an aprotic solvent-rich liquid stream.2. A process as defined in claim 1 , wherein the aqueous formaldehyde solution fed to the reactor contains formaldehyde in an amount greater than about 80% by weight.3. A process as defined in claim 1 , further comprising the step of increasing a proportionate amount of formaldehyde in the aqueous formaldehyde solution by feeding the aqueous solution through one or more concentrating devices.4. A process as defined in claim 1 , wherein the reactor comprises a fixed bed reactor claim 1 , the reactor operating at a temperature of from about 30° C. to about 200° C. and operating at ...

Cyclic Ketone Peroxide Composition

A composition comprising at least two trimeric cyclic ketone peroxides: a trimeric cyclic methyl ethyl ketone peroxide (3MEK-cp) of formula (I) and at least one peroxide satisfying formula (II) wherein Rthrough Rare independently selected from alkyl and alkoxyalkyl groups, said groups having 2 to 5 carbon atoms, the total number of carbon plus oxygen atoms of R−R+Ris in the range 7-15, and the molar ratio of 3MEK-cp to the total amount of peroxides satisfying formula (II) being in the range of from 10:90 to 80:20. 2. Composition according to wherein Rthrough Rare alkyl groups having 2 to 5 carbon atoms claim 1 , the total number of carbon atoms of R+R+Ris in the range 7-15.3. Composition according to wherein the alkyl groups are linear alkyl groups.4. Composition according to any one of the preceding claims claim 2 , wherein the molar ratio of 3MEK-cp to the total amount of peroxides satisfying formula (II) is in the range of from 40:60 to 80:20.5. Composition according to any one the preceding claims claim 2 , wherein the composition further comprises a diluent in an amount of 45-85 wt % claim 2 , based on the weight of the composition.6. Composition according to any one of the preceding claims claim 2 , wherein the total amount of trimeric cyclic ketone peroxides according to formulae (I) and (II) is in the range 15-55 wt % claim 2 , based on the weight of the composition.7. Composition according to any one of the preceding claims claim 2 , wherein at least one of the peroxides satisfying formula (II) is 3 claim 2 ,6-diethyl-3 claim 2 ,6 claim 2 ,9-trimethyl-9-(n-propyl)-1 claim 2 ,2 claim 2 ,4 claim 2 ,5 claim 2 ,7 claim 2 ,8-hexaoxonane.8. Composition according to any one of the preceding claims claim 2 , wherein at least one of the peroxides satisfying formula (II) is 3-diethyl-3 claim 2 ,6 claim 2 ,9-trimethyl-6 claim 2 ,9-(n-propyl)-1 claim 2 ,2 claim 2 ,4 claim 2 ,5 claim 2 ,7 claim 2 ,8-hexaoxonane.9. Composition according to any one of the preceding claims ...

Fluorinated crown ethers and methods and systems for extraction of lithium using same

The present disclosure provides fluorinated crown ethers. The fluorinated crown ethers have one or more pendant fluorinated groups (e.g., thioether groups with a terminal fluorinated group). The fluorinated crown ethers have desirable solubility in supercritical carbon dioxide. Also provided are methods and systems for removal of lithium (e.g., lithium ions) from aqueous samples using the fluorinated crown ethers coupled with lipophilic cation exchangers.

Benzofuran compounds, compositions and methods for treatment and prophylaxis of hepatitis c viral infections and associated diseases

The present invention relates to benzofuran derivatives and analogs, as well as compositions containing the same and to the use thereof for the treatment or prophylaxis of viral infections and diseases associated therewith, particularly those viral infections and associated diseases caused by the hepatitis C virus.

Recombinant narbonolide polyketide synthase

Recombinant DNA compounds that encode all or a portion of the narbonolide polyketide synthase are used to express recombinant polyketide synthase genes in host cells for the production of narbonolide, narbonolide derivatives, and polyketides that are useful as antibiotics and as intermediates in the synthesis of compounds with pharmaceutical value.

一种制备三聚甲醛的装置和方法

本申请提供一种制备三聚甲醛的装置和方法。该装置包括：反应器和再沸器；反应器设置有甲醛进料管、催化剂进料管、底部循环物料出料口、循环物料进料装置、顶部出料口；再沸器一端与底部循环物料出料口连接，再沸器另一端与循环物料进料装置连接。该方法包括以下步骤：1）催化剂通过催化剂进料管进入反应器中；甲醛进料管的出口设置于液相区的中下部，靠近反应器的中心线的位置；甲醛通过甲醛进料管进入反应器的液相区的中下部；2）气相区的部分物料从顶部出料口输出；3）底部循环物料出料口输出一股物料，进入再沸器中进行加热，然后回到气相区；4）循环物料回到反应器后，轻组分经顶部出料口输出物料；重组分进入液相区继续进行反应。

Process for preparing trioxane

장기간 동안 안정한 운행을 허용하는, 고체 산의 존재하에 포름알데히드 수용액으로부터 트리옥산을 제조하기 위한 실용적이고 경제적인 방법을 제공하는 것이다. The present invention provides a practical and economical method for producing trioxane from aqueous formaldehyde in the presence of a solid acid, which permits stable operation over a long period of time. 포름 알데히드 수용액으로부터 트리옥산을 제조하는 방법은 이온교환능을 갖는 물질을 사용하여 포름알데히드 수용액으로부터 주로 금속 불순물을 제거하는 제 1 기능 공정, 및 고체 산 촉매를 사용하여 금속 불순물이 제거되어진 포름알데히드 수용액으로부터 주로 트리옥산을 합성하는 제 2 기능 공정인, 2가지 기능 공정을 포함하는 장치를 사용하여 실시된다. A method for producing trioxane from an aqueous solution of formaldehyde includes a first functional step of mainly removing metal impurities from an aqueous formaldehyde solution using a substance having an ion exchange capacity and a second functional step of removing a metal impurity from the formaldehyde aqueous solution Which is a second functional process mainly for synthesizing trioxane, is carried out using an apparatus including two functional processes.

Composition based on cyclic ketone peroxides

FIELD: chemical industry. SUBSTANCE: described is transportable storage-stable peroxide composition which comprises 1.0- 90.0 wt % of one or more cyclic ketone peroxides represented by general formulae I-II wherein said peroxides are as defined in claim 1, and 10-99 wt % of one or more diluents selected from group consisting of liquid phlegmatizer for cyclic ketone peroxides, plasticizers, solid polymeric carriers, inorganic substrates, organic peroxides and mixtures thereof provided that when said diluent contains noncyclic ketone peroxide, at least 20 % of total content of active oxygen formulation should account for one or more cyclic ketone peroxides of general formulae: I-II. EFFECT: surprising degree of modification of polymer as compared with well known composition. 10 cl, 23 ex, 6 tbl бУЭ9ЭтЯ ГС ПЧ сэ (19) РОССИЙСКОЕ АГЕНТСТВО ПО ПАТЕНТАМ И ТОВАРНЫМ ЗНАКАМ ВИ "” 2 154 649 ' (51) МПК? 13) С2 С 08 Е 4/38, С 08 К 5/14, 5/15, С 07 0 323/00 12) ОПИСАНИЕ ИЗОБРЕТЕНИЯ К ПАТЕНТУ РОССИЙСКОЙ ФЕДЕРАЦИИ (21), (22) Заявка: 97102726/04, 14.07.1995 (24) Дата начала действия патента: 14.07.1995 (30) Приоритет: 21.07.1994 ЕР 94 202 136.1 (46) Дата публикации: 20.08.2000 (56) Ссылки: Ц$ 4267109 А, 12.05.1981. ЗЦ 585176 А, 25.12.1977. $Ц 1520079 А, 07.11.1989. СВ 1442681 А, 14.07.1976. ЕР 0355733 А, 28.02.1990. (85) Дата перевода заявки РСТ на национальную фазу: 21.02.1997 (86) Заявка РСТ: ЕР 95/02830 (14.07.1995) (87) Публикация РСТ: М/О 96/03397 (08.02.1996) (98) Адрес для переписки: 129010, Москва, ул. Большая Спасская 25, стр.3, ООО "Городисский и Партнеры", Лебедевой Н.Г. (71) Заявитель: АКЦО НОБЕЛЬ Н.В. (М) (72) Изобретатель: Рейндер ТОРЕНБЕК (№), Иохн МЕИЕР (МЕ), Андреас Херман ХОГТ (МЕ), Геррит БЕКЕНДАМ (МЕ) (73) Патентообладатель: АКЦО НОБЕЛЬ Н.В. (М) (54) КОМПОЗИЦИИ НА ОСНОВЕ ЦИКЛИЧЕСКИХ ПЕРЕКИСЕЙ КЕТОНА (57) Описывается транспортабельная стабильная при хранении перекисная композиция, которая содержит 1,0 - 90,0 мас.% одной или более циклических перекисей кетона, ...

Cyclic ketone peroxide compounds, improved ketone peroxide compounds

FIELD: chemistry. ^ SUBSTANCE: invention refers to cyclic ketone peroxide compounds used in (co)polymerisation and (co)polymer modification. There are disclosed cyclic ketone peroxide compounds containing one or more crystallisable cyclic ketone peroxides, paraffin and one or more retarder. In addition, there is described application of said compounds in (co)polymerisation and (co)polymer modification. ^ EFFECT: compounds develop improved safety and storage stability as compared to common cyclic ketone peroxide compounds. ^ 7 cl, 4 dwg, 1 tbl, 1 ex РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) 2 357 954 (13) C2 (51) МПК C07C 409/18 (2006.01) C07D 323/00 (2006.01) C08K 5/14 (2006.01) C08F 4/36 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ, ПАТЕНТАМ И ТОВАРНЫМ ЗНАКАМ (12) ОПИСАНИЕ ИЗОБРЕТЕНИЯ К ПАТЕНТУ (21), (22) Заявка: 2005121260/04, 26.11.2003 (24) Дата начала отсчета срока действия патента: 26.11.2003 (73) Патентообладатель(и): АКЦО НОБЕЛЬ Н.В. (NL) (43) Дата публикации заявки: 20.01.2006 2 3 5 7 9 5 4 (45) Опубликовано: 10.06.2009 Бюл. № 16 (56) Список документов, цитированных в отчете о поиске: WO 9518180 А, 06.07.1995. RU 2046793 С1, 27.10.1995. RU 2154649 С1, 20.08.2000. (85) Дата перевода заявки PCT на национальную фазу: 06.07.2005 2 3 5 7 9 5 4 R U (87) Публикация PCT: WO 2004/052877 (24.06.2004) C 2 C 2 (86) Заявка PCT: EP 03/13346 (26.11.2003) Адрес для переписки: 129090, Москва, ул. Б.Спасская, 25, стр.3, ООО "Юридическая фирма Городисский и Партнеры", пат.пов. Е.Е.Назиной, рег. № 517 (54) СОСТАВЫ С ЦИКЛИЧЕСКИМИ ПЕРОКСИДАМИ КЕТОНОВ, УЛУЧШЕННЫЕ СОСТАВЫ С ЦИКЛИЧЕСКИМИ ПЕРОКСИДАМИ КЕТОНОВ (57) Реферат: Изобретение относится к составам с циклическими пероксидами кетонов, использующимся в процессах (со)полимеризации и модификации (со)полимеров. Описываются составы с циклическим пероксидом кетона, содержащие один или несколько кристаллизующихся циклических пероксидов кетона, парафин и один или несколько стандартных флегматизаторов. Описывается также ...

Chiral sensor

Chiral compounds

본 발명은 화학식 I(여기서 X 1 , X 2 , Y 1 , Y 2 , x 1 , x 2 , y 1 , y 2 , B, C, U 1 , U 2 , V 1 , V 2 , W 1 및 W 2 는 청구항 1에서의 정의와 동일하다)의 키랄 화합물; 화학식 I의 키랄 화합물을 하나 이상 포함하는 액정 혼합물; 화학식 I의 키랄 화합물을 하나 이상 포함하는 중합가능한 혼합물을 중합시킴으로써 수득될 수 있는 키랄 선형 또는 가교결합된 액정 중합체; 액정 디스플레이, 능동 및 수동 광학 소자, 접착제, 유전 이방성 기계적 특성을 갖는 합성 수지, 화장품 및 약학 조성물, 진단제, 액정 안료에서, 장식 및 보안 목적을 위해, 비선형 광학 물질, 광학 정보 저장 매체에서, 또는 키랄 도판트로서의 화학식 I의 키랄 화합물 및 혼합물, 및 이들로부터 수득된 중합체의 용도; 및 화학식 I의 키랄 화합물을 하나 이상 포함하는 혼합물을 포함하는 액정 디스플레이에 관한 것이다. The present invention is formula I (where X 1 , X 2 , Y 1 , Y 2 , x 1 , x 2 , y 1 , y 2 , B, C, U 1 , U 2 , V 1 , V 2 , W 1 and W 2 is the same as defined in claim 1); Liquid crystal mixtures comprising at least one chiral compound of formula (I); Chiral linear or crosslinked liquid crystal polymers obtainable by polymerizing a polymerizable mixture comprising at least one chiral compound of formula (I); In liquid crystal displays, active and passive optical devices, adhesives, synthetic resins with dielectric anisotropic mechanical properties, cosmetics and pharmaceutical compositions, diagnostics, liquid crystal pigments, for decorative and security purposes, in nonlinear optical materials, optical information storage media, or The use of chiral compounds and mixtures of formula (I) as chiral dopants and polymers obtained therefrom; And a mixture comprising at least one chiral compound of formula (I).

(z)-1,4,7,10-四氧环十二烷-8-烯锂盐络合物、制备方法及其应用

本发明公开了一种(Z)‑1,4,7,10‑四氧环十二烷‑8‑烯锂盐络合物、制备方法及其应用。本发明的(Z)‑1,4,7,10‑四氧环十二烷‑8‑烯锂盐络合物其化学结构如下所示， 其中，X选自氟、氯、溴、碘、对甲苯磺酰氧、甲基磺酰氧、四氟化硼、六氟化磷、对硝基苯磺酰氧、邻硝基苯磺酰氧。本发明路线设计合理，原料安全易得，工艺安全性高，反应选择性高，提纯简单，产品纯度高，产品收率高，能充分满足产品工业化生产的需求。

Способ получения триоксана

1. Способ получения триоксана из формальдегида в газовой фазе с применением молибден-фосфорной гетерокислоты в качестве катализатора, отличающийся тем, что в качестве катализатора применяют вольфрам-молибденовые кислоты состава НPWMoOxxHO, причем n = 4-8; m = 4-8; n + m = 12; х - не выше 32.2. Способ по п. 1, отличающийся тем, что катализатор наносят на инертные носители.3. Способ по п. 1 или 2, отличающийся тем, что в качестве носителя применяют карбид кремния.4. Способ по любому из п.п. 1-3, отличающийся тем, что используют формальдегид с незначительным содержанием воды, менее 1 мас. %, в особенности с содержанием воды менее 50 м. д.5. Способ по любому из п.п. 1-4, отличающийся тем, что реакцию проводят при 80-150С, предпочтительно при 100-120С.6. Способ по любому из п.п. 1-5, отличающийся тем, что время контактирования составляет 1-30 с, предпочтительно 1-10 с.7. Способ по любому из п.п. 1-6, отличающийся тем, что парциальное давление формальдегида на входе составляет 0,5-5,0 бар, предпочтительно 0,5-2,0 бар.8. Способ по любому из п.п. 1-7, отличающийся тем, что реакцию проводят в присутствии или в отсутствии газа-носителя.9 Способ по любому из п.п. 1-8, отличающийся тем, что в качестве газа-носителя применяют азот.

Trioxepan compounds

The invention relates to compounds of formulae I and IIand compositions comprising these compounds.

Cyclic aryl ethers, thioethers, and amines and method preparation

Cyclic aryl ethers, thioethers or amines, and methods for synthesis are disclosed. These cyclic aryl compounds are synthesized by combining a first dinucleophile with a substituted benzene metallized electron-withdrawing complex, having halo or nitro substituen groups, to form a linear bimetallized aryl compound. The linear bimetallized aryl compound is then reacted with a second dinucleophile to form a cyclic bimetallized aryl compound. The metallized electron-withdrawing moieties are then removed from said cyclic bimetallized aryl compound by photolytic demetallation to form a cyclic aryl compound having the formula: ##STR1## wherein: X 1 and X 3 are the same or different and each is a alkyl, heteroalkyl, heterocyclic or aromatic group having up to 6 conjugated rings, optionally substituted; X 2 is benzene n 1 and n 3 are the same or different and each is O, S or N; and n 4 is H or lower alkyl.

Metal complexes

COMPOSITIONS WITH CYCLIC KETONE PEROXIDES, IMPROVED COMPOSITIONS WITH CYCLIC KETONE PEROXIDES

ÐÎÑÑÈÉÑÊÀß ÔÅÄÅÐÀÖÈß (19) RU (11) 2005 121 260 (13) A (51) ÌÏÊ C07D 323/00 (2006.01) ÔÅÄÅÐÀËÜÍÀß ÑËÓÆÁÀ ÏÎ ÈÍÒÅËËÅÊÒÓÀËÜÍÎÉ ÑÎÁÑÒÂÅÍÍÎÑÒÈ, ÏÀÒÅÍÒÀÌ È ÒÎÂÀÐÍÛÌ ÇÍÀÊÀÌ (12) ÇÀßÂÊÀ ÍÀ ÈÇÎÁÐÅÒÅÍÈÅ (21), (22) Çà âêà: 2005121260/04, 26.11.2003 (71) Çà âèòåëü(è): ÀÊÖÎ ÍÎÁÅËÜ Í.Â. (NL) (30) Ïðèîðèòåò: 06.12.2002 EP 02080128.8 (43) Äàòà ïóáëèêàöèè çà âêè: 20.01.2006 Áþë. ¹ 02 (86) Çà âêà PCT: EP 03/13346 (26.11.2003) (87) Ïóáëèêàöè PCT: WO 2004/052877 (24.06.2004) Àäðåñ äë ïåðåïèñêè: 129010, Ìîñêâà, óë. Á.Ñïàññêà , 25, ñòð.3, ÎÎÎ "Þðèäè÷åñêà ôèðìà Ãîðîäèññêèé è Ïàðòíåðû", ïàò.ïîâ. Ã.Á. Åãîðîâîé R U Ôîðìóëà èçîáðåòåíè 1. Ñîñòàâ ñ öèêëè÷åñêèì ïåðîêñèäîì êåòîíà, ñîäåðæàùèé îäèí èëè íåñêîëüêî êðèñòàëëèçóþùèõñ öèêëè÷åñêèõ ïåðîêñèäîâ êåòîíà, îäíî èëè íåñêîëüêî ñîêðèñòàëëèçóþùèõñ ñîåäèíåíèé, êîòîðûå çàòâåðäåâàþò â óïîì íóòîì ñîñòàâå ñ öèêëè÷åñêèì ïåðîêñèäîì êåòîíà ïðè òåìïåðàòóðå, ïðåâûøàþùåé òåìïåðàòóðó êðèñòàëëèçàöèè êðèñòàëëèçóþùåãîñ öèêëè÷åñêîãî ïåðîêñèäà êåòîíà, è, íåîá çàòåëüíî, ñîäåðæàùèé îäèí èëè íåñêîëüêî ñòàíäàðòíûõ ôëåãìàòèçàòîðîâ. 2. Ñîñòàâ ïî ï.1, â êîòîðîì, ïî ìåíüøåé ìåðå, îäèí öèêëè÷åñêèé ïåðîêñèä êåòîíà âûáðàí èç ãðóïïû, ñîñòî ùåé èç öèêëè÷åñêèõ ïåðîêñèäîâ êåòîíîâ, ïîëó÷åííûõ èç àöåòîíà, àöåòèëàöåòîíà, ìåòèëýòèëêåòîíà, ìåòèëïðîïèëêåòîíà, ìåòèëèçîïðîïèëêåòîíà, ìåòèëáóòèëêåòîíà, ìåòèëèçîáóòèëêåòîíà, ìåòèëàìèëêåòîíà, ìåòèëèçîàìèëêåòîíà, ìåòèëãåêñèëêåòîíà, ìåòèëãåïòèëêåòîíà, äèýòèëêåòîíà, ýòèëïðîïèëêåòîíà, ýòèëàìèëêåòîíà, ìåòèëîêòèëêåòîíà, ìåòèëíîíèëêåòîíà, öèêëîïåíòàíîíà, öèêëîãåêñàíîíà, öèêëîãåïòàíîíà, 2ìåòèëöèêëîãåêñàíîíà, 3,3,5-òðèìåòèëöèêëîãåêñàíîíà è ñìåñåé ïåðå÷èñëåííûõ ñîåäèíåíèé, ïðåäïî÷òèòåëüíî, ïîëó÷åííûõ èç àöåòîíà, àöåòèëàöåòîíà, ìåòèëïðîïèëêåòîíà, ìåòèëèçîïðîïèëêåòîíà, ìåòèëáóòèëêåòîíà, ìåòèëèçîáóòèëêåòîíà, ìåòèëàìèëêåòîíà, ìåòèëèçîàìèëêåòîíà, ìåòèëãåêñèëêåòîíà, ìåòèëãåïòèëêåòîíà, äèýòèëêåòîíà, ýòèëïðîïèëêåòîíà è ñìåñåé ïåðå÷èñëåííûõ ñîåäèíåíèé, à òàêæå íàèáîëåå ïðåäïî÷òèòåëüíî ïîëó÷åííûé èç ìåòèëýòèëêåòîíà. 3. Ñîñòàâ ïî ï.1 èëè 2, â êîòîðîì ...

Novel surfactant polypod compound and its manufacture

The method of purification of halogenated silane oligomer

本发明涉及一种卤化硅烷齐聚物的提纯方法，其中的卤化硅烷齐聚物可以是纯的化合物，也可以是一系列化合物的混合物，这些化合物中的每一种至少带有一个直接键合的Si‑Si，这些硅烷齐聚物的取代基只能是卤素，或者卤素和氢原子，在具有不同原子组成成分的取代基中，硅原子与其他原子的原子比必须大于3:2，在提纯的过程中，至少针对卤化硅烷齐聚物并通过分离卤化硅烷齐聚物实现提高卤化硅烷齐聚物的纯度。根据现有技术，诸如HSiCl 3 等卤化甲硅烷可以使用有机化合物(尤其是含有氨基的基团的聚合物)进行处理，对经过上述处理的混合物进行分离，即得到提纯的卤化甲硅烷。因为上述方法中使用的有机化合物中含有氨基，所以该方法不能用于提纯卤化硅烷齐聚物，因为氨基会导致副反应，并使得待提纯的产品发生分解。本发明所涉及的方法可以以高产率提纯所需的产品并且在不使用氨基的情况下实现提纯处理。对卤化硅烷齐聚物的提纯过程中使用了专门的提纯剂，此类提纯剂可以将物料中的诸如FeCl 2 之类的污染物转换成一种不溶于溶剂的形态或者不可挥发的物质。处理之后，分离提纯剂和产品，实现对物料的提纯。上述方法可以以高产率实现对物质的提纯处理，并且解决以现有技术进行提纯时出现的，诸如蒸馏时间长的问题。本文所述的提纯方法适合于将待提纯物料中诸如Si 2 Cl 6 、Si 3 Cl 8 、Si 4 Cl 10 或者分子量更大的同族体分离出来。这些方法可以用于诸如在化学气相沉积法中从卤化硅烷齐聚物和氮化硅的混合物中分离氮化硅层。

Dicyclohexyl crown ether synthesis method

本发明公开了一种二环己基冠醚类化合物的合成方法。以邻苯二酚类化合物、二氯乙醚为起始原料，经由佩德森合成方法，环化生成二苯并-18-冠-6醚类化合物，再经过催化加氢生成二环己基并-18-冠-6醚类化合物。本发明主要特征在于利用多相金属催化剂，使二苯并冠醚高效地转化为二环己基冠醚，反应完成后产物只需经过滤、浓缩等简单处理，纯度即可达到90％以上。所用多相金属催化剂制备方便、价格低廉，并且可以回收使用。

Orthoester derivatives of crown ethers as carriers for pharmaceutical and diagnostic compositions

This invention relates to A crown ether of formula (I) wherein m is 4, 5, 6, 7, or 8 and i is, independently for each occurrence, 1 or 2; at least one occurrence in the crown ether of R 1 , R 2 and the carbon to which R 1 and R 2 are attached, said carbon being bound directly to an ether oxygen of formula (I), form together a group of formula (II) wherein L is a linker which is absent or selected from a covalent bond and (CR 5 R 6 ) n , useful as carriers for pharmaceutical and diagnostic compositions.

Preparation method of cyclic polyester oligomer

本发明涉及一种环状聚酯低聚物的制备方法，属于有机合成技术领域，该制备方法以对苯二甲酸衍生物和二元醇为原料通过液‑液界面相转移缩合反应得到环状聚酯低聚物，相比于传统的解聚成环法，本发明所用原料为对苯二甲酸衍生物和二元醇，在催化剂作用下，通过控制滴速的方法，合成目标产物，合成方法简单，易于操作，具有很好的工业应用价值。

Mixture of cyclic lactic acid oligomers

Synthesis method of di-tert-butyl dicyclohexyl-18-crown-6 ether

本发明公开了一种二叔丁基二环己基‑18‑冠‑6醚的合成方法，其特征在于，包括以下步骤：将二叔丁基二苯并‑18‑冠‑6醚溶解于溶剂中，加入钌基催化剂，控制反应温度为50～100℃，氢气压力2～5 Mpa，保持搅拌，反应4～8 h；反应结束后直接过滤，分离回收钌基催化剂，所得滤液即为二叔丁基二环己基‑18‑冠‑6醚；所述的钌基催化剂为掺杂两种或两种以上金属的多金属协同作用催化剂，催化剂用量为二叔丁基二苯并‑18‑冠‑6醚质量的2～8%；本发明采用新型制备的钌基催化剂，降低了反应的温度和压力，反应安全性和反应效率大幅度提高，且催化剂可重复使用数10次，催化活性依然保持基本不变。

Dinitrodibenzo-18-crown-6 cis- and trans-isomers production method

FIELD: technological processes. SUBSTANCE: invention relates to the dinitrodibenzo-18-crown-6 cis- and trans-isomers production process, which includes the following steps: 20–25 % suspension of dibeno-18-crown-5 heating in the acetonitrile to 60–65 °C, concentrated nitric acid to the heated suspension drop by drop addition, followed by the reaction mass holding at a temperature of 60–65 °C for 20–40 minutes, cooling down precipitate to the room temperature and its filtering, acetic acid addition to the filtered precipitate, then heating the reaction mass until boiling and its boiling for 0.5–1.0 hours. After that, performing the dinitrodibenzo-18-crown-6 trans- and cis-isomers isolation from the reaction mass, at that, the trans isomer is isolated by filtration from the hot reaction mass, and the cis-isomer is isolated from the cooled down to 5 °C filtrate, after which the produced isomers are washed with water until neutral reaction and dried at 60 °C. Produced are: trans-dinitrodibenzo-18-crown-6 with the yield of 37.9 % and melting point of 246–249 °C; cis-dinitrodibenzo-18-crown-6 with the yield of 46.5 % and melting point of 208–210 °C. Dibenzocrown-ethers functional derivatives, namely, the dinitrodibenzo-18-crown-6 isomers, can be used as compound blocks in the supramolecular systems and polymeric materials. EFFECT: possibility of the produced dinitrodibenzo-18-crown-6 pure cis- and trans-isomers separation. 1 cl, 2 dwg, 3 ex РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 2 658 921 C1 (51) МПК C07D 323/00 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ОПИСАНИЕ ИЗОБРЕТЕНИЯ К ПАТЕНТУ (52) СПК C07D 323/00 (2006.01) (21)(22) Заявка: 2017123983, 06.07.2017 (24) Дата начала отсчета срока действия патента: Дата регистрации: Приоритет(ы): (22) Дата подачи заявки: 06.07.2017 (45) Опубликовано: 26.06.2018 Бюл. № 18 2 6 5 8 9 2 1 R U (56) Список документов, цитированных в отчете о поиске: Feigenbaum W.M. et al., " Novel polyamides from macrocyclic ethers", ...

Method for preparing tricycloalkylidene peroxide

Method for separating trioxymethylene by extractive distillation

本发明提供了一种萃取精馏分离三聚甲醛的方法，该方法是以一种或几种离子液体的组合为萃取剂，通过萃取精馏从三聚甲醛水溶液中提纯分离三聚甲醛；其中，所述萃取剂与三聚甲醛水溶液的质量比为0.1‑20:1；所述分离过程的温度为90‑200℃。本发明所提供的萃取精馏分离三聚甲醛的方法能够打破三聚甲醛与水的共沸点，并且所用离子液体萃取剂的饱和蒸气压低，其完全存在于液相中，不会随三聚甲醛逃逸到气相中；同时，所用离子液体萃取剂的热稳定性较好，在长时间、高温条件下不会发生热解。

Method for producing oxygen-containing macroheterocycles

FIELD: chemistry. SUBSTANCE: catalytic interaction of ethyl-2-diazo-3-oxobutyrate with 1.3-dioxolanes or 1.3-dioxanes in the presence of copper triflate (II) Cu(OTf) 2 at a temperature of 80°C for 4 hours. The reaction of ethyl 2-diazo-3-oxobutyrate with 1.3-dioxolane is carried out at the following component ratio, wt %: 1.3-dioxolane 1.5-2.3; copper triflate 0.047; ethyl-2-diazo-3-oxobutyrate 1.029-1.057; benzene 96.6-97.4. The reaction of ethyl 2-diazo-3-oxobutyrate with 1.3-dioxane is carried out at the following component ratio, wt %: 1.3-dioxane 1.7-2.5; copper triflate 0.047; ethyl-2-diazo-3-oxobutyrate 1.027-1.035; benzene 96.4-97.2. EFFECT: increasing the target product yield. 3 cl, 1 tbl РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 2 630 471 C1 (51) МПК C07D 323/00 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ОПИСАНИЕ ИЗОБРЕТЕНИЯ К ПАТЕНТУ (21)(22) Заявка: 2016147595, 05.12.2016 (24) Дата начала отсчета срока действия патента: 05.12.2016 Дата регистрации: Приоритет(ы): (22) Дата подачи заявки: 05.12.2016 (45) Опубликовано: 11.09.2017 Бюл. № 26 C 1 "Medium-Sized Rings vs Macrocycles Through Rhodium-Catalyzed Ring Expansion Reactions of Cyclic Acetals", Chemistry a European Journal, 2012, v.18, no.21, p.6626-6631. JP 2001026589 A, 30.01.2001. SU 1482919 A1, 30.05.1989. R U (54) Способ получения кислородсодержащих макрогетероциклов (57) Реферат: Изобретение относится к органической химии, этил-2-диазо-3-оксобутирата с 1,3-диоксоланом конкретно к способу получения проводят при следующем соотношении кислородсодержащих макрогетероциклов, компонентов, мас. %: 1,3-диоксолан 1,5-2,3; которые являются потенциальными биологически трифлат меди 0,047; этил-2-диазо-3-оксобутират активными веществами, например, с 1,029-1,057; бензол 96,6-97,4. Реакцию этил-2противовирусной активностью. Способ диазо-3-оксобутирата с 1,3-диоксаном проводят заключается в том, что проводят каталитическое при следующем соотношении компонентов, мас. взаимодействие этил-2-диазо ...

Preparation method and device of 2,4, 6-trioxepane

本发明涉及化工领域，具体而言，涉及一种2,4,6‑三噁庚烷的制备方法及其装置。一种2,4,6‑三噁庚烷的制备方法，甲醛与甲醇反应生成甲缩醛和2,4,6‑三噁庚烷，分离即得。本发明提供的一种2,4,6‑三噁庚烷的制备方法，由甲醛及甲醇反应获得，反应较彻底，总收率高、产品纯度高，废水污染性小，安全环保，适合工业化生产。

Cetane Number Improver, Fuel oil containing thereof and Compounds of Tetraoxanes type

본 발명은 세탄가 향상제, 이를 포함하는 연료유 및 신규한 테트라옥산계 화합물에 관한 것으로서, 더욱 상세하기로는 특정 구조의 테트라옥산계 화합물을 세탄가 향상제로서 사용하고, 상기 세탄가 향상제를 연료유에 첨가하여 연료유의 세탄가를 향상시키는 발명 및 신규한 테트라옥산계 화합물에 관한 것이다. 이러한, 본 발명의 세탄가 향상제는 기존의 세탄가 향상제 보다 독성이 적고, 안정성이 우수하며, 디젤 등의 연료유의 세탄가를 크게 향상시킴으로써, 연료유의 연소 효율을 증대시킬 수 있다. The present invention relates to a cetane number improver, a fuel oil comprising the same and a novel tetraoxane-based compound. More specifically, a tetraoxane-based compound having a specific structure is used as a cetane number improver, and the cetane number improver is added to the fuel oil to provide a fuel oil. The present invention relates to an invention for improving the cetane number and to a novel tetraoxane compound. The cetane number improver of the present invention is less toxic than conventional cetane number improvers, has excellent stability, and can greatly increase the cetane number of fuel oil such as diesel, thereby increasing the fuel efficiency of fuel oil. 세탄가 향상제, 연료유, 테트라옥산 Cetane number improver, fuel oil, tetraoxane

Preparation method of dialdehyde hemiacetal

本发明涉及一种二醛半缩醛的制备方法。具体的是一种臭氧氧化、氢气还原两步法制备二醛半缩醛的方法，在醇类溶剂采用臭氧氧化环烯烃制备半缩醛过氧化物，进一步在催化剂的作用下氢气还原得到二醛半缩醛。采用改法制备二醛半缩醛具有反应收率高、操作简单、安全性高的优点，生产成本低，具备较强的工业化价值。

Functionalised oxacalixarenes, their preparation and use in instant adhesive compositions

Oxacalixarenes of general formula I:- wherein m = 0 - 7 and n = 1 - 8 with the proviso that m + n

Polymerisable calixarene and oxacalixarene derivatives,¹polymers thereof, and use of such derivatives and polymers¹for sequestration of metals

Polymerisable calixarene and oxacalixarene derivatives wherein at least one aryl group of the macrocyclic ring has a phenolic side chain of the formula VII: wherein Z is a group containing an acrylate or methacrylate functional group. Particular derivatives are of the formula IX wherein    3 ≦ m + n + p ≦ 8    m ≧ 1    q = an integer 2-10;    a which may be the same or different on each aryl group is 0 or 1;    R³ is H, halogen, hydrocarbyl, aryl, hydrocarbylaryl or a substituted derivative thereof and R³ may be the same or different on each aryl group;    R¹¹ is H or CH₃;    R¹² is hydrocarbyl, aryl, hydrocarbylaryl or a substituted derivative thereof,    or NR12′ ₂ (wherein R12′ is H, hydrocarbyl, aryl, hydrocarbylaryl or a substituted derivative thereof),    or 0R¹⁴ (wherein R¹⁴ is hydrocarbyl, aryl, hydrocarbylaryl or a substituted derivative thereof including a N-substituted derivative thereof),    or NHNH₂, or NHOH or NHAr (wherein Ar is aryl or a substituted derivative thereof).    R¹³ is hydrocarbyl, aryl, hydrocarbylaryl or a substituted derivative thereof,    or ―CH₂X wherein X is selected from    wherein R⁷ and R⁸ which may be the same or different are H or hydrocarbyl, aryl, hydrocarbylaryl or a substituted derivative thereof;    R⁹ is ―OH, ―NH₂, ―NHC(0)NH₂ or ―NHAr, wherein Ar is aryl or a substituted derivative thereof, and    n′ is 0 or 1. Linear polymers of these compounds are formed by free radical polymerisation at the (meth)acrylate group. The compounds and their polymers are capable of sequestering etals.

A kind of metaformaldehyde manufacturing technique method and extractive reaction tower

本发明公开了一种三聚甲醛生产工艺方法及萃取反应塔，其中萃取反应塔包括设在底部的萃取剂进口、设在顶部的反应物采出口和从下至上依次设置的多级萃取反应单元，相邻萃取反应单元通过带孔塔板隔开，且相邻萃取反应单元之间还设有降液管，所述萃取反应单元内还设有固体酸催化剂。本发明具有超过45％的甲醛转化率，且具有反应过程蒸汽消耗量小，设备投入下等特点。

Organic compound having cyclic structure

The objective of the present invention is to provide a material that can increase the light-emission brightness of an electroluminescent element. The present invention provides: an organic compound having the constituent unit represented by formula (1); and a laminated structure, charge injection material and/or charge transport material, electroluminescent element, and photoelectric conversion element that contain the organic compound. (In the formula, R 1 is a (2+n 1 )-valent organic group; n 1 is an integer that is at least 1; and R 2 is a monovalent organic group. If a plurality of R 2 are present, each R 2 may be the same or different. If the number of constituent units is at least two, each constituent unit may have the same structure or a different structure as the others.)

Trioxepane compounds and composition for destruction of polypropylene and preparing polyacrylates comprising these compounds

FIELD: organic chemistry, chemistry of polymers. SUBSTANCE: invention relates to two new compounds of the formula (1) and formula (11) that are used for destruction of polypropylene. Also, invention relates to a composition used for destruction of polypropylene in preparing polyacrylates comprising compounds of formulae (1) and (11). Invention provides preparing effective initiating agents for preparing low-molecular acrylate resins. EFFECT: improved preparing method, valuable properties of compounds. 3 cl, 2 tbl, 8 dwg, 9 ex ÐÎÑÑÈÉÑÊÀß ÔÅÄÅÐÀÖÈß RU (19) (11) 2 268 264 (13) C2 (51) ÌÏÊ C07D 323/00 (2006.01) C08F 20/06 (2006.01) C08F 120/06 (2006.01) C08F 10/06 (2006.01) C08F 110/06 (2006.01) ÔÅÄÅÐÀËÜÍÀß ÑËÓÆÁÀ ÏÎ ÈÍÒÅËËÅÊÒÓÀËÜÍÎÉ ÑÎÁÑÒÂÅÍÍÎÑÒÈ, ÏÀÒÅÍÒÀÌ È ÒÎÂÀÐÍÛÌ ÇÍÀÊÀÌ (12) ÎÏÈÑÀÍÈÅ ÈÇÎÁÐÅÒÅÍÈß Ê ÏÀÒÅÍÒÓ (21), (22) Çà âêà: 2003107054/04, 08.08.2001 (24) Äàòà íà÷àëà äåéñòâè ïàòåíòà: 08.08.2001 (30) Ïðèîðèòåò: 15.08.2000 (ïï.1, 2) US 60/225,316 10.11.2000 (ïï.1-3) EP 00203943,6 (73) Ïàòåíòîîáëàäàòåëü(ëè): ÀÊÖÎ ÍÎÁÅËÜ Í.Â. (NL) (45) Îïóáëèêîâàíî: 20.01.2006 Áþë. ¹ 02 2 2 6 8 2 6 4 (56) Ñïèñîê äîêóìåíòîâ, öèòèðîâàííûõ â îò÷åòå î ïîèñêå: RU 97102726 À, 10.03.1999. SU 1531439 À1, 30.11.1994. ÅÐ 0355733 A1, 28.02.1990. (85) Äàòà ïåðåâîäà çà âêè PCT íà íàöèîíàëüíóþ ôàçó: 17.03.2003 (86) Çà âêà PCT: EP 01/09265 (08.08.2001) 2 2 6 8 2 6 4 R U Àäðåñ äë ïåðåïèñêè: 129010, Ìîñêâà, óë. Á.Ñïàññêà , 25, ñòð.3, ÎÎÎ "Þðèäè÷åñêà ôèðìà Ãîðîäèññêèé è Ïàðòíåðû", ïàò.ïîâ. Å.Å.Íàçèíîé C 2 C 2 (87) Ïóáëèêàöè PCT: WO 02/14304 (21.02.2002) (54) ÑÎÅÄÈÍÅÍÈß ÒÐÈÎÊÑÅÏÀÍÀ È ÊÎÌÏÎÇÈÖÈß ÄËß ÄÅÑÒÐÓÊÖÈÈ ÏÎËÈÏÐÎÏÈËÅÍÀ È ÏÎËÓ×ÅÍÈß ÏÎËÈÀÊÐÈËÀÒÎÂ, ÑÎÄÅÐÆÀÙÈÕ ÝÒÈ ÑÎÅÄÈÍÅÍÈß (57) Ðåôåðàò: Èçîáðåòåíè îòíîñèòñ ê äâóì íîâûì ñîåäèíåíè ì òðèîêñåïàíà ôîðìóëû I è ôîðìóëû II: êîòîðûå èñïîëüçóþòñ äë äåñòðóêöèè ïîëèïðîïèëåíà. Èçîáðåòåíèå òàêæå îòíîñèòñ ê êîìïîçèöèè äë äåñòðóêöèè ïîëèïðîïèëåíà ïðè ïîëó÷åíèè ïîëèàêðèëàòîâ, ñîäåðæàùèõ ñîåäèíåíè I è II. Òåõíè÷åñêèé ðåçóëüòàò - ýôôåêòèâíûå èíèöèàòîðû äë ïîëó÷åíè ...

Method for producing trioxane

본 발명은 다음 단계 (1) 내지 (4): (1) 고농도의 포름알데히드 수용액을 제조하는 단계, (2) 상기 단계 (1)에서 얻어진 고농도의 포름알데히드 수용액을 고체산 촉매가 충전된 반응기로 이송하여 트리옥산을 형성하는 단계,(3) 상기 단계 (2)에서 제조된 트리옥산을 함유하는 포름알데히드 수용액을 어떠한 상변화도 일으킴이 없이 추출기로 도입하여. 트리옥산의 것보다 높은 비점을 가지며 트리옥산과의 어떤 공비조성물도 없는 비수용성 유기용매로 그 트리옥산을 추출하는 단계, 및 (4) 상기 단계(3)를 완료한 후, 수상중의 포름알데히드 농도를 높이고 수상을 단계(2)의 반응기로 복귀시키면서, 유기용매상을 중류에 의해 트리옥산과 유기용매로 분리하여 증류탑 상부에서는 트리옥산을 취출하고 증류탑 하부에서 얻어진 유기용매는 단계 (3)으로 복귀시키는 단계로 이루어지는 것을 특징으로 하며, 전 공정을 통한 에너지 절약을 목적으로 하는, 포름알데히드 수용액으로부터 트리옥산을 제조하는 방법을 제공한다.

Synthesis method of di-tert-butyl dicyclohexyl-18-crown-6 ether

本发明公开了一种二叔丁基二环己基‑18‑冠‑6醚的合成方法，其特征在于，包括以下步骤：将二叔丁基二苯并‑18‑冠‑6醚溶解于溶剂中，加入钌基催化剂，控制反应温度为50～100℃，氢气压力2～5 Mpa，保持搅拌，反应4～8 h；反应结束后直接过滤，分离回收钌基催化剂，所得滤液即为二叔丁基二环己基‑18‑冠‑6醚；所述的钌基催化剂为掺杂两种或两种以上金属的多金属协同作用催化剂，催化剂用量为二叔丁基二苯并‑18‑冠‑6醚质量的2～8%；本发明采用新型制备的钌基催化剂，降低了反应的温度和压力，反应安全性和反应效率大幅度提高，且催化剂可重复使用数10次，催化活性依然保持基本不变。

Orthoester derivatives of crown ethers as carriers for pharmaceutical and diagnostic compositions

本发明涉及可用作药物的和诊断组合物的载体的式（I）的冠醚，其中m是4、5、6、7、或8，并且i每次出现独立地是1或2；在冠醚中至少一次出现R 1 、R 2 以及R 1 和R 2 连接在其上的碳，所述碳直接地结合到式（I）的醚氧上，共同形成式（II）的基团，其中L是连接子，其不存在或选自共价键和(CR 5 R 6 ) n 。

METHOD FOR MANUFACTURING MACROCYCLIC POLYAETERS

Method for synthesising monohalomethyl-substituted dibenzo crown ether

FIELD: chemistry. SUBSTANCE: invention relates to a method for synthesysing monohalomethyl-substituted dibenzo crown ether by the formula I, consisting in an interaction of the corresponding dibenzo crown ether with formaldehyde and hydrogen halide, formalin is used as a source of formaldehyde, concentrated hydrochloric and hydrobromic acids are used as hydrogen halides, and glacial acetic acid is used as a solvent, at a temperature of 20 to 25°C, with a hydrohalic acid:dibenzo crown ether:formaldehyde ratio of 10:1:3,4. EFFECT: technical result is development of a new method for obtaining a compound by the formula (I) with a high yield, applicable in synthesis of polymer catalysts for phase transfer of anhydride hydrolysis reaction. 1 cl, 6 ex РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 2 750 938 C1 (51) МПК C07D 323/00 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ОПИСАНИЕ ИЗОБРЕТЕНИЯ К ПАТЕНТУ (52) СПК C07D 323/00 (2021.05) (21)(22) Заявка: 2020141853, 18.12.2020 (24) Дата начала отсчета срока действия патента: Дата регистрации: 06.07.2021 (45) Опубликовано: 06.07.2021 Бюл. № 19 2 7 5 0 9 3 8 R U (56) Список документов, цитированных в отчете о поиске: ТАШМУХАМЕДОВА А.К. и др., Химия гетероциклических соединений, 4, 1989, с.470-474. СТЕМПНЕВСКАЯ И.А. и др., Химия природных соединений, 5, 1982, с. 665666. Y. NAKAMURA ET AL., Tetrahedron Letters, 41, 2000, pp. 2193-2197. SU 1784268 A1, 30.12.1992. RU 2178788 C1, 27.01.2002. (54) Способ получения моногалогенметилзамещенного дибензо-краун-эфира (57) Реферат: Изобретение относится к способу получения Технический результат - разработан новый моногалогенметилзамещенного дибензо-краунспособ получения соединения формулы (I) с эфира формулы I, который заключается во высоким выходом, которое находит свое взаимодействии соответствующего дибензоприменение при синтезе полимерных краун-эфира с формальдегидом и катализаторов межфазного переноса реакции галогенводородом, в качестве источника гидролиза ангидридов. ...

Chiral compounds

本发明涉及通式I的手性化合物，其中X 1 ，X 2 ，Y 1 ，Y 2 ，x 1 ，x 2 ，y 1 ，y 2 ，B，C，U 1 ，U 2 ，V 1 ，V 2 ，W 1 和W 2 具有在权利要求1中给出的意义，涉及包括通式I的至少一种手性化合物的液晶混合物，涉及可通过聚合包括通式I的至少一种手性化合物的可聚合混合物来获得的手性线性或交联的液晶聚合物，涉及通式I的手性化合物和从它获得的混合物和聚合物在液晶显示器，有源和无源的光学元件，粘合剂，具有各向异性机械性能的合成树脂，化妆品和药物组合物，诊断剂，液晶颜料中，用于装饰性和安全应用，非线性光学，光信息存储器或作为手性掺杂剂的用途，以及涉及包括包含通式I的至少一种手性化合物的混合物的液晶显示器。

Method for the production of polyoxymethylene homopolymers or copolymers by homopolymerizing or copolymerizing trioxane, starting from methanol

本发明提出了一种以甲醇(1)为原料，通过三噁烷的均聚或共聚来制备聚甲醛均聚物或共聚物(7)的方法，其中，将甲醇(1)在第一生产装置(A)的第一反应器中氧化以生成一种含甲醛的水物流(2)，将所述水物流进料到第二生产装置(B)中，在所述第二生产装置中获得纯三噁烷(6)。在该方法中，通过蒸馏分离低沸点馏分(5)，并且将所述纯三噁烷(6)进料到第三生产装置(C)中，在所述第三生产装置中所述纯三噁烷(6)进行均聚或共聚而形成聚甲醛均聚物或共聚物(7)。所公开的方法的特征在于，将低沸点馏分(5)的物流从分离低沸点馏分的塔(K2)循环回所述第一生产装置(A)中第一反应器的进料中。

Cyclic ketone peroxide composition

FIELD: chemistry. SUBSTANCE: object of the invention is an initiator composition containing at least two trimeric cyclic ketone peroxides: trimeric cyclic methyl ethyl ketone peroxide (3MEK-cp) of formula (I) and at least one peroxide satisfying formula (II) in which R 1 –R 3 represent alkyl, where these groups have from 2 to 5 carbon atoms, the total number of carbon atoms in R 1 +R 2 +R 3 is in the range of 7–15, and the molar ratio of 3MEK-cp and the total amount of peroxides satisfying formula (II) is in the range from 10:90 to 80:20. Invention also relates to a process for the preparation of this composition. (I) (II). EFFECT: improving the safety and stability of the composition during storage. 11 cl, 6 tbl, 6 ex РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (13) 2 679 146 C2 (51) МПК C07D 323/00 (2006.01) C08F 4/38 (2006.01) C08F 8/50 (2006.01) C08K 5/14 (2006.01) C10L 1/18 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ОПИСАНИЕ ИЗОБРЕТЕНИЯ К ПАТЕНТУ (52) СПК C07D 323/00 (2006.01); C08F 4/38 (2006.01); C10L 1/1811 (2018.08); C08K 5/14 (2006.01) (21)(22) Заявка: 2016138813, 09.03.2015 (24) Дата начала отсчета срока действия патента: Дата регистрации: 06.02.2019 11.03.2014 EP 14158878.0 (43) Дата публикации заявки: 11.04.2018 Бюл. № (56) Список документов, цитированных в отчете о поиске: RU 2154649 С2, 20.08.2000 & WO 96/03397 A1, 08.02.1996. RU 2224756 C2, 27.02.2004. RU 2351661 C2, 10.04.2009 & WO 2004972059 A1, 26.08.2004. 11 (45) Опубликовано: 06.02.2019 Бюл. № 4 (86) Заявка PCT: C 2 C 2 (85) Дата начала рассмотрения заявки PCT на национальной фазе: 11.10.2016 EP 2015/054800 (09.03.2015) (87) Публикация заявки PCT: 2 6 7 9 1 4 6 WO 2015/135865 (17.09.2015) R U 2 6 7 9 1 4 6 (73) Патентообладатель(и): АКЦО НОБЕЛЬ КЕМИКАЛЗ ИНТЕРНЭШНЛ Б.В. (NL) Приоритет(ы): (30) Конвенционный приоритет: R U 09.03.2015 (72) Автор(ы): ВАН ДЕР СХЮР Ян Мартейн (NL), НЮЙСИНК Йохан (NL), МИЛЛЕ Рено Шарль Жозеф (SE), ФИШЕР Барт (NL) Адрес для переписки: 129090, Москва, ул. ...

Process for the production of carboxylic acid esters, ethers or acetals of 2, 5-dimethylhexane-2, 5-dihydroperoxide

Process for synthesizing triformol using ionic liquid

本申请公开了一种合成三聚甲醛的方法，其中使用甲醛水溶液作为反应物，催化剂为一种酸性离子液体，催化剂的用量为0.01～10重量％。

Method of producing pentaoxaspyroalkanes

FIELD: chemistry. SUBSTANCE: invention relates to organic chemistry, particularly to a method of producing pentaoxaspyroalkanes of general formula (1) involving 1,1-1,1-bis(hydroperoxy)cycloalkanes (where the cycloalkane is cyclopentane, or cyclohexane or cycloheptane or cyclooctane or cyclododecane) reaction with formaldehyde in presence of catalyst Sm(NO 3 ) 3 ·6H 2 O, and the molar ratio of 1,1-bis(hydroperoxy)cycloalkane : formaldehyde of Sm(NO 3 ) 3 ·6H 2 O = 10:20:(0.3-0.7), at room temperature (20 °C) and atmospheric pressure in tetrahydrofuran as a solvent for 4-6 hours. EFFECT: these compounds can be used as preparations having an antimalarial activity; the output of pentaoxaspyroalkanes (1) is equal to 65-97 %. 1 cl, 1 tbl, 1 ex РОССИЙСКАЯ ФЕДЕРАЦИЯ (19) RU (11) (51) МПК C07D 323/00 (13) 2 601 315 C1 (2006.01) ФЕДЕРАЛЬНАЯ СЛУЖБА ПО ИНТЕЛЛЕКТУАЛЬНОЙ СОБСТВЕННОСТИ (12) ОПИСАНИЕ (21)(22) Заявка: ИЗОБРЕТЕНИЯ К ПАТЕНТУ 2015122318/04, 10.06.2015 (24) Дата начала отсчета срока действия патента: 10.06.2015 (45) Опубликовано: 10.11.2016 Бюл. № 31 2 6 0 1 3 1 5 (54) СПОСОБ ПОЛУЧЕНИЯ ПЕНТАОКСАСПИРОАЛКАНОВ (57) Реферат: Изобретение относится к области атмосферном давлении в тетрагидрофуране в органической химии, в частности к способу качестве растворителя в течение 4-6 ч. Эти получения пентаоксаспироалканов общей соединения могут найти применение в качестве формулы (1), заключающегося в том, что 1,1-1,1препаратов, обладающих противомалярийной бис(гидроперокси)циклоалканы (где циклоалкан активностью. Выход пентаоксаспироалканов (1) - циклопентан, или циклогексан, или циклогептан, составляет 65-97%. 1 табл., 1 пр. или циклооктан, или циклододекан) подвергают взаимодействию с формальдегидом в присутствии катализатора Sm(NO3)3·6H2O, и мольном соотношении 1,1-бис(гидроперокси)циклоалкан : формальдегид : Sm(NO3)3·6H2O = 10:20:(0.3-0.7), R U при комнатной температуре (20°С) и (56) (продолжение): "Chemical transformation of solvent-derived ozonolysis products: acid-catalysed ...

Method of manufacturing trioxane

기상으로 포름알데히드로부터 트리옥산을 촉매적으로 제조하는 본 발명의 방법은 스팀에 의해 활성화되거나 활성화될 수 없는 바나딜 인산수소·1/2수화물을 포함하는 촉매를 사용한다. 본 방법은 부산물이 없으며 공간-시간 수율이 높다. 반응기내 침착물도 존재하지 않는다.

Crown ether compound and application thereof

本发明公开了一种冠醚类化合物及其应用，其作为胶粘剂，化学结构明确，成分单一，不需要添加各种辅助物质，粘附过程简单，无需有机溶剂参与，避免了因溶剂的存在，而使被粘物变形、错位和收缩等弊病，应用于水下粘附玻璃、有机玻璃、金属、聚四氟乙烯板乃至各种生物组织(如猪皮)等材料，是一种操作方便、粘附速度快、可防水、粘附能力强、可重复使用、无有机溶剂、绿色环保的胶粘剂。

A kind of no sulfuric acid process metaformaldehyde synthesizer and its synthesis route

本发明公开了化学工艺技术领域的一种无硫酸法三聚甲醛合成装置及其合成工艺路线，包括主反应器、预反应器、催化精馏塔、冷凝器、萃取罐、再沸器、出料泵、侧线采出泵和回流泵，该种无硫酸法三聚甲醛合成装置及其合成工艺路线，以酸性固体酸树脂作为催化剂，以高浓度甲醛作为反应原料，采用催化精馏的方法合成和初步提纯三聚甲醛，初步反应后进入催化精馏塔将反应生成的三聚甲醛，水，甲醛，实现三聚甲醛，水、甲醛，高沸物杂质的初步分离，固体酸催化剂分离简单同时生产过程中没有硫酸加入，反应物料对设备材质腐蚀相对较小，节约材料投资，不产生废酸，合成三聚甲醛所得粗三聚甲醛含量高于现行主流工艺，因此后续分离能耗降低。

Method of production of kraun-ethers

Crown ether derivatives of the general formula I …<CHEM>… wherein… Z<1> is a group of the general formula …<CHEM>… (in which Ra represents an alkyl group having 1-4 carbon atoms and Rb represents an alkyl group having 1-20 carbon atoms) are useful in the preparation of ion-selective electrodes having a long lifetime.

Asymmetric aldol reaction method with chiral lead catalyst

Method for preparing extrapure fluorosulfonylimide with removing methallic cation

The present invention relates to a process for the preparation of a fluorosulfonylimide salt in which metal cations are completely removed. The process of the present invention is a very economically efficient process in which a fluorosulfonylimide salt is obtained by completely removing the metal cation with respect to the fluorosulfonylimide content or by using only 1% or less of crown ether relative to the lithium salt and hydrate content Can be manufactured. As a result, it is expected that the efficiency of the obtained fluorosulfonylimide salt is ensured and the cell efficiency is also improved. On the other hand, the fluorosulfonylimide salt having a reduced content of impurities produced by the method of the present invention has a problem that the capacity of an electrochemical device such as a secondary cell, a capacitor, a capacitor, It is possible to provide a high-performance electrolyte fluorosulfonylimide salt that is difficult to generate.

Process for preparing trioxane from gaseous formaldehyde and catalyst therefor

NOVEL URANYLE ION CAPTURING AGENTS AND PROCESS FOR THEIR PREPARATION

AGENTS DE CAPTURE DES IONS URANYLE. ILS SONT CONSTITUES PAR DES COMPOSES COMPRENANT UN POLYMERE LIE CHIMIQUEMENT A AU MOINS UN DES GROUPEMENTS X, X ET X D'UN COMPOSE MACROCYCLIQUE REPRESENTE PAR LA FORMULE GENERALE: (CF DESSIN DANS BOPI) TRAITEMENT NOTAMMENT DE L'EAU DE MER, POUR EN EXTRAIRE LES IONS URANYLE. URANYLE ION CAPTURING AGENTS. THEY ARE CONSTITUTED BY COMPOUNDS INCLUDING A POLYMER CHEMICALLY BOUND TO AT LEAST ONE OF THE X, X AND X GROUPS OF A MACROCYCLIC COMPOUND REPRESENTED BY THE GENERAL FORMULA: (CF DRAWING IN BOPI) TREATMENT IN PARTICULAR OF SEA WATER, FOR EXTRACT URANYLE IONS.

Calix¦4¦arènes-cronnes, their preparation process and their use for the selective extraction of cesium and actinides.

NEW COMPLEXES FOR CATION SEPARATION

L'invention concerne des complexes comprenant un matériau à structure matricielle comportant des domaines complexant des terres rares ou des métaux stratégiques, leur procédé de préparation, et leur utilisation pour extraire ou séparer les terres rares ou les métaux stratégiques dans un milieu aqueux ou organique.

Tricycloalkylidene peroxides - from 1-hydroxy-1'-hydro peroxydicyclohexyl peroxide or 1, 1'-dihydroperoxydicycloalkyl peroxi

Tricycloalkylidene peroxides are prepd. by reacting 1-hydroxy-11-hydroperoxydicyclohexyl peroxide or a 1,11-dihydroperoxydicyloalkyl peroxide with a cyclic ketone in an organic solvent contg. a strong acid catalyst. The rings may carry substituents. Dicyclohexylidene-2-methylcyclohexylidene peroxide, dicyclohexylidene octylidene peroxide, dicyclohexylidene cyclododecylidene peroxide, dicyclohexylidene-3-methyl-5-methoxycyclohexylidene peroxide, dicyclododecylidene cycloheptylidene peroxide and dicyclododecylidene cyclopentylidene peroxide are claimed. The peroxides are intermediates for macrocyclic products. They can also be used to crosslink polymers and as polymerisation initiators. They have antiparasitic, esp. antimalarial, activity. Solid ketones can be used. New peroxides can be obtained in high yield. The peroxide soln. obtained can be used directly for the conversion to macrocyclic cpds.

Crown-ethers used as active ingredients of ionselective membrane electrodes

Crown ether derivatives of the general formula I …<CHEM>… wherein… Z<1> is a group of the general formula …<CHEM>… (in which Ra represents an alkyl group having 1-4 carbon atoms and Rb represents an alkyl group having 1-20 carbon atoms) are useful in the preparation of ion-selective electrodes having a long lifetime.

PROCESS FOR THE PREPARATION OF TRIOXANE

Patent FR2469410B1

Process for the production of metaldehyde

Macrocyclic polyethers containing aromatic residues and their cationic complexes

Process for curing polyepoxides using heterocyclic polymercaptans and resulting products

Trioxane stabilised with phenolic cpds. - also chlorohydrocarbons, pref. 1,1,1- trichloroethane stabilised with this mixture

Trioxane is stabilised, partic. against oxidn., by incorporating 0.1-20% based on the trioxane, of >=1 phenol chosen from (a) monophenols contg. 1 or 2 benzene rings opt. substd. by 1-6C alkyl and/or 1-2C alkoxy, and 1-2C alkyl ethers of monophenols, (b) diphenols contg. 1 or 2 benzene rings opt. substd. by 1-6C alkyl and 1-2C alkyl ethers of these phenols, (c) triphenols with a phenyl ring opt. substd. by 1-4C alkyl. Also 1-2C chloro-substd. satd. aliphatic hydrocarbons contain 0.01-15% trioxane and 0.001 to 3% of at least one phenol as (a) to (c) above and 0.1 to 7.5% of a 1-5C alcohol, 0.1 to 4% of an up to 4C cyclic ether or an up to 8C linear ether, 0. to 4% of an up to 4C nitroalkane, 0 to 5% of an alkyl nitrile or alkenyl nitrile up to 4C, and 0 to 5% of a alkyl ketone up to 6C. Also 1,1,1-trichloroethane contains 0.01-15% trioxane and 0.001 to 3% of an >=1 phenol (a) to (c), 0.1-7.5% of tert. -butanol, 0.1-4% of butylene oxide, 0-4% of nitromethane, 0-5% of acetonitrile and 0-5% of methylethylketone. Used particularly for stabilising 1,1,1-trichloroethane against degradation by contact with metals such as Fe etc., the time of stabilisation at present is 1/4 -48 hrs. is insufficient for cases where the trichloroethane is used for long periods such as degreasing and cleaning metals or dry cleaning clothes and textiles. The above stabilisation of the trioxane renders it more effective.

Process for the purification of cyclic aldehyde oligomers