СОЕДИНЕНИЕ КЕТОНА ИЛИ ОКСИМА И ГЕРБИЦИД

Настоящее изобретение относится к соединению оксима или его соли формулы (1), которое может быть использовано в качестве гербицида:,где B представляет собой кольцо из любого одного из B-1-а или B-2-а; Q представляет собой =NOR; а R, R, R, R, R, R-R, A, Z, Z, Z, m, n имеют значения, указанные в формуле изобретения. 2 н. и 1 з.п. ф-лы, 26 табл., 23 пр.

БИЦИКЛИЧЕСКОЕ АРОМАТИЧЕСКОЕ СОЕДИНЕНИЕ, ФАРМАЦЕВТИЧЕСКАЯ И КОСМЕТИЧЕСКАЯ КОМПОЗИЦИИ

Изобретение относится к новым биоароматическим соединениям общей формулы I, где значения R1, R2, R3, X и Ar указаны в п.1 формулы. Они обладают активностью в областях дифференциации и пролиферации клеток. Описывается также фармацевтическая композиция, предназначенная для лечения дерматологических, ревматических, респираторных, сердечно-сосудистых и офтальмологических заболеваний, а также и косметическая композиция для гигиены тела и для ухода за волосами. 3 с. и 13 з.п.ф-лы, 4 ил.

ГЕТЕРОЦИКЛИЧЕСКИЕ КОНДЕНСИРОВАННЫЕ БЕНЗОИЛГУАНИДИНЫ, ИХ ПОЛУЧЕНИЕ И ИХ ПРИМЕНЕНИЕ В КАЧЕСТВЕ ИНГИБИТОРОВ КЛЕТОЧНОГО NA+/H+-АНТИНОСИТЕЛЯ

... 1. Циклические сульфоны формулы I где R1 и R2 обозначают соответственно независимо друг от друга Н, А, СF3, CH2F, CHF2, C2F5, Hal, ОН, ОА, NH2, NHA, NA2, NO2 или CN; X обозначает CR4R5; C = Z, O, S, NH, NA или NR3; Y обозначает CR6R7, C = Z, O, NH, NA или NR3; Z обозначает O, S, NH, NA, NOH, NOA, CH2, СНА или CA2; R4, R5, R6; R7 обозначают соответственно независимо друг от друга Н, A, R3, Hal, ОН, ОА, SH, SA, NH2 NHA или NA2 или же R5 и R6 или R7 и R8 обозначают соответственно вместе также связь, причем в каждой молекуле может появляться максимально только одна подобная связь; R4 и R5 обозначают вместе также О-(CH2)2-O или O-(СН2)3-O; R8 и R9 обозначают соответственно независимо друг от друга Н или А; А обозначает алкил с 1-6 С-атомами, На1 обозначает F, Сl, Вr или I и R3 обозначает фенил или бензил незамещенный или замещенный одно-, дву- или трехкратно А, ОА, NH2, NHA, NA2, F, Cl, Br и/или СF3 и n обозначает 0 или 1, и их физиологически приемлемые соли. 2. Соединения по п.1, представляющие ...

Способ получения 3-бром-2-метил-5-фенилтиофена

СПОСОБ ПОЛУЧЕНИЯ З-БРОМ-2МЕТИЛ-5-ФЕНИЛТИОФЕНА на основе дибромпроизводного 2-метилтиофена с использованием металлорганического синтеза в эфирной среде, о т л ичающийся тем, что, с целью упрощения процесса, в качестве дибромпроизводного 2-метилтиофена используют 3,4-дибром-2-метил-5-фенилтиофен , который подвергают взаимодействию с магнием в присутствии дибромэтана при кипении реакционной смеси с последующим добавлением дизтилоксалата и кислотным гидролизом полученной смеси.

Способ получения производных 1-оксо-5-инданилоксиуксусной кислоты

VERFAHREN ZUR HERSTELLUNG VON AROMATISCHEN SULFONSAEUREN

Neue Thienylcarbonsäureester von Aminoalkoholen, ihre Quaternierungsprodukte sowie die Herstellung und Verwendung dieser Verbindungen.

PROCESS FOR PREPARING 7BETA-ACYLAMINO-7ALPHA-ALKOXY-CEPHALOSPORINS

Oxime carbamates and oxime carbonates for the protection of cultivated crops

Oxime carbamates and oxime carbonates of the formula Ar-CX= N-O-CO-R, wherein Ar is a phenyl, naphthyl, fury or thienyl group, which may carry certain substituents, or Ar is a carboxylic ester or carbamyl group, X is cyano, lower alkanoyl, carboxylic ester, -COOH, hydrogen, carboxylic amide, halogen or lower alkyl, and -COR is one of certain carboxylic amide, ester or thioester groups, are suitable as antidotes for the protection of cultivated plants against harmful agricultural chemicals, in particular against herbicides which are insufficiently compatible with the cultivated plants. These compounds of the formula I can be used either on their own or together with the agricultural chemicals. One of the possibilities offered is the dressing or immersion treatment of seed or of seedlings, of the crop to be protected, with solutions or dispersions of compounds of the formula I.

New derivatives of the carboxylic acid cyclopropane, their preparation, their application to the fight against the parasites and the compositions containing them.

N (heterocyclic aminocarbonyl) aryl sulphonamides weedkillers, compositions the container and processes using them.

Derived from 2-cyclohexene-1-one.

HERBICIDES AND PLANT GROWTH-ADJUSTING MEANS AND THEIR USE

MITTEL ZUM SCHUTZ VON KULTURPFLANZEN VON AGGRESSI-VEN HERBIZIDEN

VERFAHREN ZUR HERSTELLUNG VON NEUEN SALICYLANILID-DERIVATEN UND IHREN SALZEN

HERBIZIDE UND PFLANZENWACHSTUMSREGULIERENDE MITTEL UND DEREN VERWENDUNG

PROCEDURE FOR the PRODUCTION OF NEW ONE 3 (2 ' PERHALOGENALKYLVINYL) - 2,2-DIMETHYLCYCLOPROPANCARBONSAEUREESTERN

PROCEDURE FOR the PRODUCTION OF NEW ONE 2-CYCLOHEXEN-1-ON-DERIVATEN

PROCEDURE FOR THE PRODUCTION OF AN OPTICALLY ACTIVE ONE OF ALDEHYDE INTERMEDIATE PRODUCT

PROCEDURE FOR THE PRODUCTION OF NEW SALICYLANILID DERIVATIVES AND YOUR SALTS

PROCEDURE FOR THE PRODUCTION OF AN OPTICALLY ACTIVE ONE OF ALDEHYDE INTERMEDIATE PRODUCT

FUNGICIDE MEANS

PROCEDURES FOR THE PRODUCTION OF NEW SUBSTI TUIERTEN AMINO ACIDS AND/OR THEIR ESTERS AND YOUR SALTS

PROCEDURE FOR THE PRODUCTION OF NEW SUBSTITUTED ACETIC ACID ESTERS

RETROVIRALE PROTEASE INHIBITORS

MORE CYCLOHEXENONOXIMETHER, PROCEDURES AND INTERMEDIATE PRODUCTS FOR YOUR PRODUCTION AND YOUR USE THAN HERBICIDES

NEW ONE AZIRIDIN AND PHENAETHANOLAMINDERIVATE.

FUNGICIDE MEANS

Prostaglandins and analogues as agents for lowering intraocular pressure

OXIME CARBAMATES AND OXIME CARBONATES

COMPOUNDS WITH TERMINAL AMINOCARBOXYLIC ACID GROUPING

PYRROLIDINE DERIVATIVES

These are described novel pyrrolidine derivatives of the general formula (I) , wherein R1 represents the 2-thienyl group or a phenyl group substituted by a lower tertiary amino group, R2 and R3 each independently represent a hydrogen atom or a lower alkyl group and R4 represents a phenyl group which may be substituted by halogen, lower alkyl, lower alkoxy, nitro or primary, lower secondary or lower tertiary amino, with the proviso that R1 represents a phenyl group substituted by a lower tertiary amino group when R4 represents a phenyl or halo-substituted phenyl group, and acid addition salts thereof which show analgesic activity without being addictive.

PROCESS FOR PRODUCING OPTICALLY ACTIVE 2- (2',2'-DIHALOVINYL)-CYCLOPROPANE-1- CARBOXYLIC ACIDS SUBSTITUTED IN THE 3-POSITION, AND DERIVATIVES THEREOF, AS WELL AS NOVEL 4-(2',2', 2'-TRIHALOETHYL)-CYCLOBUTANE-1-SULFONIC ACID SALTS

A novel process for the preparation of optically active 2-(2',2'-dihalogenovinyl)-cyclopropane-1-carboxylic acids substituted in the 3-position, and derivatives thereof, and also novel 4-(2',2',2'-trihalogenoethyl)-cyclobutane-1-sulfonic acid salts are described. In the said process, racemates of specific cyclobutanones are reacted either with the sulfurous acid salt of an optically actlve base or in the presence of water and sulfur dloxide with an optically actlve base to give a 4 (2',2',2'-trihalogenoethyl)-cyclobutane-1-sulfonic acid salt. The resulting pure diastereomers are either reacted direct in the presence of a base to give optically active 2-(2',2'-dihalogenovinyl)-cyclopropane-1-carboxylic acids or acid derivatives, or, alternatively, the pure diastereomers are decomposed to optically active cyclobutanones, after which the latter are converted in the presence of a base to the desired optically active cyclopropanecarboxylic acids, which in the main are obtained in the cis-configuration ...

OXIME CARBAMATES AND OXIME CARBONATES FOR THE PROTECTION OF CULTIVATED CROPS

Oxime carbamates and oxime carbonates of the formula I given herein are suitable as antidotes for the protection of cultivated plants against harmful agricultural chemicals, in particular against herbicides which are insufficiently compatible with the cultivated plants. These compounds of the formula I can be used either on their own or together with the agricultural chemicals. One of the possibilities offered is the dressing or immersion treatment of s ed or of seedlings, of the crop to be protected, with solutions or dispersions of compounds of the formula I.

DERIVES DE L'ACIDE CYCLOPROPANE CARBOXYLIQUE, LEUR PREPARATION, ET LEUR APPLICATION A LA LUTTE CONTRE LES PARASITES

INDENYL ACETIC ACIDS AND PROCESSES FOR PREPARING SAME

(1-OXO-2-ARYL OR THIENYL-2-SUBSTITUTED-5-INDANYLOXY (OR THIO)) NOIC ACIDS AND DERIVATIVES THEREOF AND PROCESSES FOR PREPARING SAME

CONDENSED HETEROCYCLIC PYRAZOLE DERIVATIVES AS KINASE INHIBITORS

Bicyclo-pyrazole compound of formula (I) and pharmaceutically acceptable salts thereof, as defined in the specification, processes for their preparation, combinatorial libraries comprising a plurality of them and pharmaceutical compositions thereof, are herewith disclosed: the compounds of the invention are useful, in therapy, as protein kinase inhibitors, for instance in the treatment of cancer.

PROCESS FOR PRODUCING ENYNE DERIVATIVES

A process for producing an enyne derivative of the formula: wherein R1 is a hydrogen atom, a lower alkyl group, a halo lower alkyl group, a lower alkenyl group, a lower alkynyl group or a cycloalkyl group, R2 is a hydrogen atom or a group of the formula: wherein each of R3, R31 and R32 which may be the same or different, is a hydrogen atom or a lower alkyl group, each of R4, R5, R41 and R51 which may be the same or different, is a hydrogen atom, a halogen atom, a hydroxyl group, a lower alkyl group or a lower alkoxy group, R42 is a hydroxyl group, a halogen atom, a group of the formula B-O- (wherein B is a protecting group for a hydroxyl group), a hydroxymethyl group, a formyl group, a carboxyl group, a lower alkoxycarbonyl group, a lower alkanoyl group, an amino group, a mercapto group or a group of the formula R6-X-Y- (wherein R6 is a phenyl or thienyl group which may have one or two substituents selected from the group consisting of a halogen atom, a hydroxyl group, a lower alkyl ...

SUBSTITUTED 4-BIARYLBUTYRIC OR 5-BIARYLPENTANOIC ACIDS AND DERIVATIVES AS MATRIX METALLOPROTEASE INHIBITORS

Inhibitors for matrix metalloproteases, pharmaceutical compositions containing them, and a process for using them to treat a variety of physiological conditions. The compounds of the invention have the generalized formula (T) x A-B-D-E-G, wherein A and B are aryl or heteroaryl rings; each T is a substituent group; x is 0, 1 or 2; the group D represents (a), (b), (c), (d), or (e); the group E represents a two or three carbon chain bearing one to three substituent groups which are independent or are involved in ring formation, possible structures being shown in the text and claims; and the group G represents -PO3H2, -M, (f), (g), or (h), in which M represents -CO2H, -CON(R11)2, or -CO2R12; and R13 represents any of the side chains of the 19 noncyclic naturally occurring amino acids, and include pharmaceutically acceptable salts thereof.

MITTEL ZUR BEEINFLUSSUNG DER PFLANZENENTWICKLUNG.

PROCEDURE FOR THE PRODUCTION OF CEPHALOSPORINDERIVATEN.

PROCEDURE FOR THE PRODUCTION OF SALICYLANILID DERIVATIVES.

FOR CONTROL OF UNWANTED VEGETATION APTITUDE SULFONAMIDHALTIGE COMPOSITIONS, PRODUCTION AND USE THE SAME.

PROCEDURES FOR THE PRODUCTION OF NEW SUBSTITUTED AMINO ACIDS.

PROCEDURE FOR THE PRODUCTION OF ECYL CYANIDES.

Process for the preparation of [1-oxo-2-aryl- or -thienyl-2-subst.-5-indanyloxy-(or -thio)]alkanecarboxylic acids and their derivatives

Process for the preparation of thienylpolyenes

PROCESS FOR PREPARING DERIVATIVES OF CYCLOPENTANE.

PROCEDURE FOR the PRODUCTION of a 6,6,6-TRIHALOGEN-3,3-DIMETHYL-4-HEXENSAEUREESTERS.

Process for the preparation of [1-oxo-2-aryl- or -thienyl-2-subst.-5-indanyloxy- (or -thio)]alkanecarboxylic acids or their alkyl esters

... [1-Oxo-2-aryl- or -thienyl-2-subst.-5-indanyloxy- (or -thio)]alkanecarboxylic acids or their alkyl esters of the formula are prepared. The substituents in the formula are described in Claim 1. These compounds are obtained by reacting an appropriately substituted [1-oxo-2-aryl- or -2-thienyl-5-indanyloxy- (or -thio)]alkanecarboxylic acid or a lower alkyl ester thereof with an alkylating agent which supplies the radical R. The resulting compounds, which are in the form of the free acid, can be converted into lower alkyl esters or salts. The corresponding amides are likewise prepared from compounds of the formula I which are in the form of the free acid by converting the acid with thionyl chloride into the acid chloride and then reacting the latter with an amine. The resulting compounds have therapeutic activity and can be used, in particular, in diuretic and saluretic agents.

CYCLOPROPANECARBOXYLIC ACID DERIVATIVES, THEIR USE FOR PEST CONTROL AND COMPOSITIONS CONTAINING THEM.

PESTICIDE.

Dye for dye-sensitized solar cell and dye-sensitized solar cell

Disclosed is a dye for dye-sensitized solar cells, which exhibits high affinity and adhesion to porous metal oxides, while having excellent solubility in organic solvents. The dye for dye-sensitized solar cells contains a specific phosphorylthiophene compound represented by formula (1). A dye-sensitized solar cell using the dye for dye-sensitized solar cells is also disclosed.

DERIVED ACYLES SUBSTITUTE AMINO-ACIDS, HAS ACTIVITY ANTI-HYPERTENSIVE

PROCESS FOR THE PREPARATION OF 7-B-ACYLAMINO 7 A- ALCOXYCEPHALOSPORINES

N-(HETEROCYCLIQUE AMINOCARBONYL)ARYL SULFONAMIDES HERBICIDES, COMPOSITIONS LES CONTENANT ET PROCEDES LES UTILISANT

L'invention se rapporte à la chimie organique. Elle concerne des composés de la formule ...

NOVEL BICYCLIC DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

NOVEL BICYCLIC DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Composés de formule (I) : où R1, R2, R3, R4, R5, R6, R7, R8, R14, W, A et n sont tels que définis dans la description. Médicaments.

Sulfonation of aromatic compounds in the presence of solvents

QUATERNARY THENYL PHOSPHONIUM SALTS

Insecticidal substituted acetate compounds

CHEMICAL DERIVATIVES AND THEIR APPLICATION LIKE AGENT ANTITELOMERASE

CHEMICAL DERIVATIVES AND THEIR APPLICATION LIKE AGENT ANTITELOMERASE

CHEMICAL DERIVATIVES AND THEIR APPLICATION LIKE AGENT ANTITELOMERASE

Liquid-crystalline medium comprising stabiliser

PHOTOCHEMICAL REACTION PREPARATIVE METHOD OF FOUR-MEMBERED RING COMPOUNDS

The photochemical reaction preparative method of the four-membered ring compounds of general formula I or II is provided, wherein the light source is the mixing light source or single band light source with the wave length of 250nm to 500nm, and the use of the said compounds in the domain of chemistry, biology and medical science as B type G protein couple receptor regulator is also provided.

FLUORESCENT NUCLEOSIDE ANALOGS AND COMBINATORIAL FLUOROPHORE ARRAYS COMPRISING SAME

The present invention provides fluorescent nucleoside analogs which comprise a fluorescent cyclic compound joined to a carbon of a sugar molecule such as pentose, hexose, ribose or deoxyribose or analogs thereof in either an α or β configuration. The subject compounds are useful as probes in the study of the structure and dynamics of nucleid acids and their complexes with proteins. In addition, the subject compounds are useful in any technique which uses labeled oligonucleotides for detection. Non-fluorescent spacer molecules in which a cyclohexane, cyclohexene, decalin, or benzene is joined to a carbon of a sugar moiety such as pentose, hexose, ribose or deoxyribose are also provided. Also provided are the 5' dimethoxytrityl-3'-O-phosphoramidite derivatives, suitable for incorporation into oligonucleotides by automated synthesizers. Combinatorial fluorophore array (CFA) libraries comprising oligomers of the subjects nucleoside analogs attached to one or more solid supports are also provided ...

Novel sulfonamides

The present invention provides wherein R1 is selected from the group consisting of C1-C10 alkoxy, OH and NR4R5; R2 is selected from the group consisting of C1-C10 alkyl and (CH2)nOH; R3 is selected from the group consisting of C1-C10 alkyl, heteroaryl, e.g. thienyl, furanyl and pyridyl, phenyl, mono, -di-, tri-substituted phenyl and heteroaryl; R4 and R5 are independently selected from the group consisting of H, C1-C10 alkyl, C1-C10 alkyl hydroxyl; m is 0 or an integer from 1 to 3 and n is an integer of from 1 to 4. These compounds are useful in lowering intraocular pressure and/or treating glaucoma or providing neuroprotection to the eye of a human patient.

Process for the production of thiophenes from alpha-methylene ketones in the single-stage process and new ortho-fused thiophenes produced by means of the process

Described is a novel process which can be carried out as a single-stage synthesis for the production of substituted and/or b,d- ortho-fused thiophenes. Serving as starting compounds and α-methylene ketones which are reacted in an preferably alcoholic solvent with bromine whereafter the formed intermediate product after separation from the solvent is reacted directly with a sulphurising agent. Preferably under reflux conditions in a suitable solvent to form the end product. In this way also hitherto unknown ortho-fused thiophene compounds are synthesized more especially those with 5 or 9 rings condensed with one another.

Optically active phenyl acetates

Substituted acetate compounds represented by the formula which are useful as pesticides and pesticidal composition containing the substituted acetate compounds as active ingredients, as well as processes for preparing the compounds and the compositions are disclosed.

SMALL-MOLECULE MODULATORS OF MELANIN EXPRESSION

The present invention relates to small molecule modulators of melanin expression and methods of making the small molecules. Also disclosed are methods of increasing pigmentation in a cell which involve providing compounds of the present invention and contacting a cell with the compounds under conditions effective to induce melanin expression in the cell, thereby increasing pigmentation. The present invention also relates to compositions containing compounds of the present invention and a carrier.

Mono-, oligo- and poly-bis(thienyl)arylenes and their use as charge transport materials

The invention relates to the use of mono-, oligo- and poly-bis(thienyl) arylenes as charge transport materials or semiconductors in electrooptical, electronic and electroluminescent devices, to charge transport and semiconductor materials, components and devices comprising mono-, oligo- and poly-bis(thienyl) arylenes, and to novel mono-, oligo- and poly-bis(thienyl) arylenes.

Pesticidal compounds

A compound of Formula (I): (I) R1(CA=CA1)x-C(=X)NR²R3 where R1 is alkyl optionally substituted by a group selected from alkoxy, alkenyl, alkynyl, alkenyloxy, alkynyloxy, aryl, aryloxy, arylalkoxy and cycloalkyl fused to an aryl ring; x = 1 or 2; X = O or S; each A and A1 is independently hydrogen, alkyl or haloalkyl; R² is alkyl, alkenyl or cycloalkyl any of which may be substituted by halo, alkenyl, alkyl, cycloalkyl, alkynyl, dioxalanylalkyl or alkoxy; and R3 is selected from groups (A) to (D): (A) -Y=X1-(R4)a where X1 is O or S, Y is phosphorus or carbon, R4 is hydrogen, alkyl, alkoxy, acyl or CO2R5 where R5 is alkyl or aryl, and a is 1 or 2 (B) -S(R6)(O)b where R6 is alkyl, aryl, aryloxy, alkoxy, thioalkoxy, thioaryl, alkythio, alkoxythio or arylthio and b is 0, 1 or 2 (C) -S(O)cNR7R8 where c is 0, 1 or 2, R7 is -COR9 or -CO2R9 where R9 is hydrogen, alkyl or a fluorine atom, a group (A) or (B) as defined above, or alkyl substituted by acyl, carboalkoxy or cyano, and R8 is alkyl (D) ...

NEW COMPOUNDS

СЛОЖНЫЕ ЭФИРЫ ТИЕНИЛКАРБОНОВОЙ КИСЛОТЫ И АМИНОСПИРТОВ, СПОСОБ ИХ ПОЛУЧЕНИЯ И ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ, ОБЛАДАЮЩАЯ АНТИХОЛИНЕРГИЧЕСКОЙ АКТИВНОСТЬЮ

Использование: в фармакологии в качестве лекарственных средств. Заявленные соединения получают путем переэтерификации метилового эфира ди-(2-диенил)гликолевой кислоты соответствующим спиртом. Продукт: сложный скопиновый эфир ди-(2-тиенил)гликолевой кислоты, т. пл. 238 - 241oC (разложение) 2 с. и 2 з.п. ф-лы, 5 табл., 1 ил.

ДИЗАМЕЩЕННЫЕ ФУРАНОНЫ, ТИАЗОЛЫ И ПЕНТЕНОНЫ В КАЧЕСТВЕ ИНГИБИТОРОВ ЦИКЛООКСИГЕНАЗЫ, СПОСОБ ИХ ПОЛУЧЕНИЯ, ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ И СПОСОБ ЛЕЧЕНИЯ

Описывается соединение формулы 1 или его фармацевтически приемлемая соль, где X-Y-Z выбирают из группы, включающей в себя a) -C(O)CH2CH2-, b) -С(O)-O-CR5(R5)-, c) -S-N= CH, d) -CH=N-S-, когда сторона b) представляет собой двойную связь, а сторона a) и c) представляют собой простые связи; и X-Y-Z представляет группу =N-S-CH=, когда стороны a и c представляют собой двойные связи, а сторона b представляет собой простую связь; R1 выбирают из группы, включающей в себя a) S(O)2CH3, b) S(O)2NH2, c) S(O)2NHC(O)CF3; R2 выбирают из группы, включающей в себя a) C3, C4, C5, C6 и C7-циклоалкил, b) моно-, ди- или тризамещенный фенил, в котором заместители выбирают из группы, включающей в себя (1) водород, (2) галоген, (3) C1-6-алкокси, (4) C1-6-алкилтио, (5) -CO2H; R5 и R6 каждый независимо выбарают из группы, включающей в себя (a) водород, (b) C1-6-алкил. Описывается также способ получения вышеуказанных соединений, способ лечения и фармацевтическая композиция на основе соединений формулы 1 для лечения ...

S-ЗАМЕЩЕННЫЕ N-1-[(ГЕТЕРО)АРИЛ]АЛКИЛ-N'-[(ГЕТЕРО)АРИЛ]АЛКИЛИЗОТИОМОЧЕВИНЫ, СПОСОБ ИХ ПОЛУЧЕНИЯ, ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ, СПОСОБ ИЗУЧЕНИЯ ГЛУТАМАТЭРГИЧЕСКОЙ СИСТЕМЫ, СПОСОБЫ ЛЕЧЕНИЯ (ВАРИАНТЫ)

... 1. S-замещенные N-1-[(гетеро)арил]алкил-N’-1-[(гетеро)арил]алкилизотиомочевины общей формулы I в которой Y и Z могут быть одинаковыми или различными и независимо представляют возможно замещенный арил или возможно замещенный (возможно частично или полностью гидрированный) гетероарил; знак (#) обозначает возможность наличия хирального атома углерода; R1 и R2 могут быть одинаковыми или различными и независимо представляют Н или низший алкил; R3 представляет низший алкил, возможно замещенный алкенил, возможно замещенный циклоалкил, циклоалкенил, аралкил или группу общей формулы -(CH2)n-W, в которой n=1-4, a W выбран из группы, состоящей из возможно замещенного арила, возможно замещенного (возможно частично или полностью гидрированного) гетероарила, возможно замещенного циклоалкила, этенила, необязательно моно-, или ди-замещенного низшим алкилом, группы COOR5, в которой R5 представляет Н, низший алкил, фенил, группы CH2OR5, в которой R5 имеет значения, определенные выше, группы NR6R7, в которой ...

Способ получения производных салициланилида

VERFAHREN ZUR HERSTELLUNG VON ACYLCYANIDEN (B)

NEUE CYCLOPROPANCARBONSAEUREDERIVATE, DEREN HERSTELLUNG, DEREN VERWENDUNG BEI DER BEKAEMPFUNG VON PARASITEN UND DIE SIE ENTHALTENDEN ZUSAMMENSETZUNGEN

NEW ANTIPARASITIC AND PESTICIDAL DERIVATIVES OF CYCLOPROPANE CARBOXYLIC ACIDS

2-HYDROXYLIMINOALKYL-2-CYCLOHEXENE-1-ONE DERIVATIVES

... 1455200 2 - Hydroxyliminoalkyl - 2 - cyclohexen-1-ones and their herbicidal compositions NIPPON SODA CO Ltd 17 Dec 1974 [24 Dec 1973] 54405/74 Heading C2C The invention comprises compounds of general Formula I wherein R is a phenyl or C 1-6 alkyl group; R2 is a C 1-4 alkyl, C 3 or C 4 alkenyl, propargyl, (C 1-4 alkoxy)methyl, methyl thiomethyl or benzyl group; substituents X are selected from C 1-6 alkyl, (C 1-2 alkoxy) carbonyl, styryl, furyl, thienyl or phenyl which is optionally substituted by one or more halogen, methyl or methoxy groups or X is a polymethylene group -(CH 2 -)-m where m is 4 or 5, n is 0 or an integer from 1 to 3; Z is a substituent R-A- or T in which A is or -SO 2 -, T is methyl or benzyl and R is a C 1-2 alkyl, phenyl, optionally substituted by at least one halogen, methyl, methoxy or introgroup, benzyl, phenoxymethyl or halogen substituted phenoxymethyl group. The compounds of Formula I may be prepared by reacting a compound of Formula III in which R 1 , ...

INHIBITORS OF RETROVIRALER PROTEASEN

PROCEDURE FOR THE PRODUCTION OF ECYL CYANIDES

PROCEDURE FOR the PRODUCTION OF NEW ONE 3 (2 ' PERHALOGENALKYLVINYL) - 2,2-DIMETHYLCYCLOPROPANCARBONS [UREESTERN

FUNGIZIDES MITTEL

VERFAHREN ZUR HERSTELLUNG VON ACYLCYANIDEN

VERFAHREN ZUR HERSTELLUNG VON NEUEN 7BETA- -ACYLAMIDO-3-CEPHEM VERBINDUNGEN MIT ENDSTAENDIGER AMINOCARBONSAEUREGRUPPIERUNG IN DER ACYLAMIDOSEITENKETTE

PROCEDURE FOR THE PRODUCTION OF THIOPHENEN FROM ALPHA METHYLENKETONEN IN THE POTTING PROCEDURE AND MEANS OF THE PROCEDURE MANUFACTURE NEW ONE ANELLIERTE THIOPHENE.

MEANS TO THE PROTECTION OF CULTIVATED PLANTS OF AGGRESSIVE HERBICIDES

PROCEDURE FOR THE PRODUCTION OF ECYL CYANIDES

PROCEDURE FOR THE PRODUCTION OF O-SUBSTITUTING HYDROXYLAMINEN.