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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Применить Всего найдено 5985. Отображено 100.

26-04-2012 дата публикации

Composition, method for preparing same, and use thereof for improving the fluidity and temperature resistance of composite materials

Номер: US20120101192A1

Автор: Cedric Dever, Jacques Barbier

Принадлежит: Valagro Carbone Renouvelable Poitou Charentes SAEM

A composition or master batch including at least one functionalized polyglycerol, at least one biopolymer, and a meal obtained from plant carbon, and its use for improving the fluidity in the molten state and the heat resistance of composite materials, in particular composites based on biopolymers that are optionally loaded with plant meal. Also, a process for the preparation of this composition, as well as the materials that integrate it.

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Номер записи: 1

07-06-2012 дата публикации

Process of Producing Thermoplastic Starch/Polymer Blends

Номер: US20120139154A1

Автор: Hongbo Li, Michel Huneault

Принадлежит: NATIONAL RESEARCH COUNCIL OF CANADA

A process of producing a thermoplastic starch/polymer blend involves introducing dry starch into a twin-screw extruder at a first location along the extruder, introducing a plasticizer into the twin-screw extruder at a second location along the extruder downstream of the first location to form a starch paste and then gelatinizing the starch paste in the extruder to form thermoplastic starch, and, introducing dry polymer at ambient temperature into the twin-screw extruder at a third location along the extruder downstream of the second location to form a blend with the thermoplastic starch in the extruder.

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Номер записи: 2

28-06-2012 дата публикации

Aqueous composition for enteric hard capsule, method of preparing enteric hard capsule, and enteric hard capsule prepared using the method

Номер: US20120161364A1

Автор: Eun Hee Park, Hyon Ho Baek, Jae Uk Cha, Jin Ryul Son, Min Gyu Song, Sung Wan Lee

Принадлежит: Samsung Fine Chemicals Co Ltd

An aqueous composition for an enteric hard capsule, a method of preparing an enteric hard capsule, and an enteric hard capsule prepared using the method. The aqueous composition for an enteric hard capsule includes an enteric base material, a capsule forming aid, and a neutralizing agent. The method of preparing an enteric hard capsule includes: preparing an aqueous composition by dissolving an enteric base material, a capsule forming aid, and a neutralizing agent in water; preheating the aqueous composition to a temperature that is less than the gelation temperature for the aqueous composition; immersing a mold pin heated to a temperature that is greater than the gelation temperature for the aqueous composition into the aqueous composition; taking the mold pin out of the aqueous composition to obtain a film formed on the mold pin; and maintaining the film at a temperature that is equal to or greater than the gelation temperature for the aqueous composition for a predetermined period of time to fix the film on the mold pin and drying the film.

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Номер записи: 3

09-08-2012 дата публикации

Foaming agent for plastics

Номер: US20120202902A1

Автор: David Kümmet, Hendrik Wermter, Rainer Schnee, Rüdiger WISSEMBORSKI, Thomas Futterer

Принадлежит: Chemische Fabrik Budenhiem KG

A process for the production of foamed plastic parts, in which a blowing agent composition is introduced into a plastic matrix and causes pore formation in the plastic matrix by releasing at least carbon dioxide gas from the blowing agent composition, wherein the blowing agent composition contains at least one carbon dioxide carrier selected from carbonates, hydrogen carbonates and carbamates of alkali metals, alkaline earth metals, aluminum, transition metals and/or ammonium, and at least one acid carrier.

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Номер записи: 4

07-03-2013 дата публикации

Capsule having broad color spectrum

Номер: US20130058989A1

Автор: Cale E. Murray

Принадлежит: Qualicaps Inc

The present invention is directed to a capsule comprising a water-soluble compound suitable for the capsule, and a mixture of colorant agents, wherein the color of the capsule may be in the range of 15<L<90; −30<a<+75; −37<b<+46 as measured in accordance with the Lab color space. The present invention further includes capsules containing a filling such as food, medicine, cosmetics, agrichemicals, feed or active biological ingredient.

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Номер записи: 5

14-03-2013 дата публикации

Biodegradable pellets foamed by irradiation

Номер: US20130065055A1

Автор: Catia Bastioli, Daniele Turati, Matteo Nicolini, Roberto Lombi

Принадлежит: Novamont SpA

This invention relates to biodegradable starch-based pellets which foamable by irradiation, which are particularly suitable for the manufacture of foam articles, characterised in that they have a porous structure with a low porous external skin. This invention also relates to foam articles obtained from these.

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Номер записи: 6

28-03-2013 дата публикации

COPOLYESTER BLENDS WITH ENHANCED TEAR STRENGTH

Номер: US20130079440A1

Автор: Hasty Noel M., Stancik Edward J., Teasley Mark F., Wilczek Lech

Принадлежит: E I DU PONT DE NEMOURS AND COMPANY

This invention relates to aliphatic-aromatic copolyesters that can exhibit improved tear strength and improved rate of biodegradation. Particularly to an aliphatic-aromatic copolyester having a dicarboxylic acid component and a glycol component. The invention also relates to articles and blends using the copolyesters. 1. A blend comprising an aliphatic-aromatic copolyester consisting essentially of a. about 95 to 40 mole percent of terephthalic acid component;', 'b. about 5 to 60 mole percent of a linear aliphatic dicarboxylic acid component; and', 'c. about 0 to 30 mole percent of an alicyclic dicarboxylic acid component; and, 'I. a dicarboxylic acid component consisting essentially of, based on 100 mole percent total acid component a. about 100 to 76 mole percent of a linear aliphatic glycol component;', 'b. about 0 to 4 mole percent of a dialkylene glycol component; and', 'c. about 0 to 30 mole percent of an alicyclic glycol component;, 'II. a glycol component consisting essentially of, based on 100 mole percent total glycol componentwherein Ic+IIc>2 mole percent,and at least one other polymeric material.2. The blend of wherein said other polymeric material is a natural polymer.3. The blend of wherein said other polymeric material is selected from the group consisting of a natural polymer claim 2 , starch claim 2 , and poly(lactic acid).4. A shaped article comprising the blend of .5. A film comprising the blend of .6. The film of with tear strength greater than about 5000 g/mm according to ASTM D1922.7. The film of with tear strength greater than about 8000 g/mm according to ASTM D1922.8. The film of with tear strength greater than about 16000 g/mm according to ASTM D1922. This invention relates to blends containing aliphatic-aromatic copolyesters and other polymers. The blends can exhibit improved tear strength and improved rate of biodegradation.As population increases, resources become scarce and societal habits have a greater impact on our environment. ...

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Номер записи: 7

28-03-2013 дата публикации

Starch/rubber latex compound and method for manufacturing same using coupling reagent

Номер: US20130079441A1

Автор: Hyun Chul Cho, Hyung Seok Kim, Jong Hyuk Lim, Seok Min JANG, Ur Ryong Cho

Принадлежит: Hyundai Motor Co, Industry University Cooperation Foundation of Korea University of Technology and Education

Disclosed is a rubber composition obtained by chemically blending rubber with a filler, particularly in which Latex rubber is directly blended with a starch solution obtained by gelatinizing starch in water. Herein, as a coupling agent between Latex rubber and starch, resorcinol-formaldehyde is used. By this, a vulcanized rubber compound is prepared. When resorcinol-formaldehyde is used as a coupling agent during the blending of the Latex rubber with the gelatinized starch solution, it is possible to solve the problem of tensile strength lowering caused by low affinity with rubber. Furthermore, it is possible to inhibit starch loss caused by high water-solubility, during the blending of starch in a liquid state. Also, the physical property of the vulcanized rubber compound can be varied according to the amount of the added coupling agent.

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Номер записи: 8

18-04-2013 дата публикации

TEMPERATURE-SENSITIVE CARRIER FOR CARRYING A PHYSIOLOGICALLY ACTIVE SUBSTANCE AND PREPARATION METHOD THEREOF

Номер: US20130095186A1

Автор: JUNG Young Seok, Na Kun

Принадлежит:

The present invention relates to a temperature-sensitive carrier for carrying a physiologically active substance and a preparation method thereof. Specifically, the temperature-sensitive carrier according to the present invention comprises an amphiphilic biodegradable block copolymer containing polysaccharide or polysaccharide and succinic anhydride as a hydrophilic block and polylactide as a non-ionic block. A hydrophilic polymer-polylactide copolymer according to the present invention forms a stable complex with a physiologically active substance such as protein, polynucleotide and the like in vivo via ionic bonding and temperature-sensitive hydrophobic bonding. Therefore, a copolymer according to the present invention can facilitate in vivo delivery of a physiologically active substance and used as an in vivo drug delivery system. 1. A temperature-sensitive carrier for carrying a physiologically active substance , which comprises a copolymer of (i) a combination of a polysaccharide and succinic anhydride and (ii) polylactide.2. The temperature-sensitive carrier according to claim 1 , wherein said polysaccharide is inherently charged and comprises a non-toxic unit having a molecular weight of at least 5 claim 1 ,000.3. The temperature-sensitive carrier according to claim 2 , wherein said polysaccharide is a hydrophilic pullulan or hyaluronic acid derivative.4. The temperature-sensitive carrier according to claim 1 , wherein (i) a combination of a polysaccharide and succinic anhydride and (ii) polylactide are combined in the weight ratio of 1:0.5 to 1:5.5. The temperature-sensitive carrier according to claim 1 , wherein said carrier is combined with at least one physiologically active substance selected from the group consisting of protein claim 1 , peptide claim 1 , nucleotide and small organic compounds having a hydrophobic or hydrophilic functional group.6. The temperature-sensitive carrier according to claim 5 , wherein said physiologically active substance is ...

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Номер записи: 9

18-04-2013 дата публикации

PLANT MATERIAL COMPOSITIONS AND METHOD FOR PREPARING SAME

Номер: US20130096236A1

Автор: Beaudoux Didier, Bernaerts Joel, Constant Bernard, Coudyser Laurie, Mentink Leon

Принадлежит: ROQUETTE FRERES

The present invention relates to a novel thermoplastic composition, characterized in that it contains: a) 15% to 60% of at least one starchy material; b) 10% to 30% of at least one starchy material plasticizer; c) 15% to 70% of at least one polyolefin; and d) 10% to 40% of at least one plant material selected among plant fibers and plant fillers. The invention also relates to a thermoplastic composition preparation method that includes the following steps: (i) selecting at least one composition (a) containing at least one starchy material, one plasticizer of said starchy material, and one polyolefin; (ii) selecting at least one plant material (b) selected among plant fibers and plant fillers, said plant material being formed of particles, the dimensions of which are between 0.5 and 5000 micrometers; and (iii) mixing the composition (a) and the plant material (b) so as to obtain the thermoplastic composition according to the invention. 121-. (canceled)22. A thermoplastic composition , comprising:a) from 15 to 60% of at least one amylaceous material,b) from 10 to 30% of at least one plasticizing agent for amylaceous material with a molar mass of greater than 18 g/mol and less than 5000 g/mol,c) from 15 to 65% of at least one polyolefin, andd) from 10 to 40% of at least one plant material chosen from plant fibers and plant fillers,said amylaceous material a) being plasticized by the plasticizing agent b) and these percentages being expressed by dry weight, with respect to the dry weight of said composition.23. The composition according to claim 22 , wherein it comprises:a) from 15 to 50% of at least one amylaceous material,b) from 10 to 25% of at least one plasticizing agent for amylaceous material.c) from 25 to 50% of at least one polyolefin, andd) from 15 to 40% of at least one plant material chosen from plant fibers and plant fillers.24. The composition according to claim 22 , wherein it comprises claim 22 , in total claim 22 , at least 27% claim 22 , or from 30 to ...

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Номер записи: 10

18-04-2013 дата публикации

STARCH-BASED COMPOSITIONS FOR LATEX REPLACEMENT

Номер: US20130096239A1

Автор: Biltresse Stephane, Bregola Massimo, Timmermans Maurice

Принадлежит: Cargill, Incorporated

A method for producing starch-based compositions, and the composition produced therewith, for use as latex substitutes for full or partial latex replacement in applications such as carpet backing. 117.-. (canceled)18. A process for the production of a starch-based composition , the process comprising:a) providing a starch product, wherein the starch product is a cold water soluble starch product;b) reacting the starch product with a stabilizing agent;c) neutralizing the stabilized starch product; andd) functionalizing the starch product obtained in step (c).19. The process of claim 18 , wherein the starch product is selected from the group consisting of starch claim 18 , starch derivatives claim 18 , and mixtures thereof.20. The process of claim 18 , wherein the stabilizing agent is selected from the group consisting of an unsaturated organic compound with two or more hydrophilic polar groups claim 18 , precursors of the unsaturated organic compound claim 18 , oligomers based on the unsaturated compound claim 18 , and mixtures thereof.21. The process of claim 18 , wherein the stabilizing agent is itaconic acid.22. The process of claim 18 , wherein the stabilizing agent is used in an amount of 0.5 to 10% by weight based on the total dry weight of the starch product.23. The process of claim 18 , wherein step (b) further comprises reacting the starch product with an initiator.24. The process of claim 23 , wherein the initiator is a persulfate.25. The process of claim 18 , wherein functionalizing comprises reacting the starch product obtained in step (c) with a reagent selected from the group consisting of a wet strength agent claim 18 , a plasticizer claim 18 , and mixtures thereof.26. The process of claim 18 , further comprising thinning the starch product prior to step (c).27. The starch-based composition obtained by the process of .28. A binder composition comprising:{'claim-ref': {'@idref': 'CLM-00027', 'claim 27'}, 'the composition of ; and, optionally,'}latex.29. ...

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Номер записи: 11

09-05-2013 дата публикации

Compositions and methods for increasing poultry hatchability and early performance

Номер: US20130116174A1

Автор: Billy Hargis, Walter Bottje

Принадлежит: University of Arkansas

Compositions and methods of improving poultry hatch health are provided herein. Poultry hatch health and hatchability may be improved by administering compositions in ovo prior to hatch. The compositions include iodinated tyrosine-containing proteins, suitably iodinated casein, and carbohydrates.

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Номер записи: 12

30-05-2013 дата публикации

POLYPHASE BIODEGRADABLE COMPOSITIONS CONTAINING AT LEAST ONE POLYMER OF VEGETABLE ORIGIN

Номер: US20130136879A1

Автор: Capuzzi Luigi

Принадлежит: Novamont S.p.A.

Polyphase biodegradable compositions having a good resistance to ageing comprising a continuous phase comprising at least one hydrophobic polyester and at least one dispersed phase of polymer of vegetable origin. The hydrophobic polyester constituting the continuous phase is incompatible with the polymer of vegetable origin. The compositions comprise a plasticiser comprising at least 75% of a mixture of diglycerol, triglycerol and tetraglycerol. 1. Polyphase biodegradable compositions having good resistance to ageing comprising:(a) a continuous phase comprising at least one hydrophobic polyester,(b) at least one dispersed phase comprising at least one polymer of vegetable origin,in which the hydrophobic polyester of the continuous phase is incompatible with the polymer of vegetable origin, said compositions being characterised by the fact of comprising 2-70% by weight, with respect to the weight of the polymer of vegetable origin, of a plasticizer comprising at least 75% by weight, with respect to the total weight of said plasticizer, of a mixture of diglyerol, triglycerol and tetraglycerol.2. Polyphase biodegradable compositions according to claim 1 , comprising:(a) as regards the continuous phase, at least one hydrophobic polyester in a percentage of between 98 and 45% by weight with respect to the sum of components (a) and (b),(b) as regards the dispersed phase, at least one polymer of vegetable origin in a percentage between 2 and 55% by weight with respect to the sum of components (a) and (b).3. Polyphase biodegradable compositions according to in which the hydrophobic polyester is of the diacids-diol type.4. Polyphase biodegradable compositions according to claim 3 , in which said hydrophobic polyester of the diacids-diol type is aliphatic-aromatic.5. Polyphase biodegradable compositions according to in which the aliphatic-aromatic polyester of the diacid/diol type contains as the aliphatic acid an acid selected from oxalic acid claim 4 , malonic acid claim 4 ...

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Номер записи: 13

06-06-2013 дата публикации

Edible adhesive

Номер: US20130142926A1

Автор: Olga Romero Busqué, Rafael Alfredo Fernandez De Muniain Comajuncosa

Принадлежит: Individual

The present invention relates to a method of manufacturing an edible glue comprising preparing a solution of starches, the preparation of a solution of preservatives, the mixing of the solution of preservatives to the solution of starches, the preparation of a solution of organic acids and the mixing of the organic acid mixture to the mixture of starches and preservatives, giving an edible glue comprising a mixture of starch, a mixture of organic acids, a mixture of preservatives and water.

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Номер записи: 14

06-06-2013 дата публикации

Low-profile additives on the basis of renewable resources

Номер: US20130144002A1

Автор: Bauers Florian, Zarka Michael Tobias

Принадлежит: Wacker Chemie AG

The invention relates to the use of polymers on the basis of renewable resources as LPA, characterized in that the polymers on the basis of renewable resources can be obtained by the radically initiated polymerization of one or more ethylenically unsaturated monomers in the presence of one or more renewable resources selected from the group consisting of carbohydrates and natural rubbers. 1. A method of making a composite component , comprising curing a radically crosslinkable polymer composition comprising one or more radically crosslinkable polymers , one or more ethylenically unsaturated monomers selected from unsaturated polyester resins and vinyl ester resins , optionally initiators , optionally fillers , and optionally further additions , and said radically crosslinkable polymer composition further comprising one or more polymers based on renewable raw materials obtained by radically initiated polymerization of one or more ethylenically unsaturated monomers in the presence of one or more renewable raw materials selected from the group consisting of carbohydrates and natural rubbers.2. The method as claimed in claim 1 , wherein the ethylenically unsaturated monomers are selected from the group consisting of vinyl esters claim 1 , (meth)acrylic esters claim 1 , vinylaromatics claim 1 , olefins claim 1 , 1 claim 1 ,3-dienes claim 1 , and vinyl halides.3. The method as claimed in claim 1 , wherein the polymers based on renewable raw materials comprise one or more monomer units from the group consisting of vinyl acetate claim 1 , vinyl esters of α-branched monocarboxylic acids having 9 to 11 C atoms claim 1 , vinyl chloride claim 1 , ethylene claim 1 , methyl acrylate claim 1 , methyl methacrylate claim 1 , ethyl acrylate claim 1 , ethyl methacrylate claim 1 , propyl acrylate claim 1 , propyl methacrylate claim 1 , n-butyl acrylate claim 1 , n-butyl methacrylate claim 1 , 2-ethylhexyl acrylate claim 1 , and styrene.4. The method as claimed in claim 1 , wherein the ...

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Номер записи: 15

20-06-2013 дата публикации

COMPOSITION COMPRISING NANOPARTICLES AND A METHOD FOR THE PREPARATION THEREOF

Номер: US20130152823A1

Автор: Al Deyab Salem S., El-Naggar Mehrez El-Sayed, Fouda Moustafa Mohamed Gaballa El-Sayed, Shaheen Tharwat Ibrahim

Принадлежит: KING SAUD UNIVERSITY

The present invention relates to a composition comprising nanoparticles stabilized by an at least partially deprotonated biopolymer and a method for the preparation thereof. 1. Composition comprising nanoparticles stabilized by an at least partially deprotonated biopolymer.2. Composition according to claim 1 , wherein the nanoparticles are metal and/or metal oxide nanoparticles.3. Composition according to claim 1 , wherein the biopolymer is starch.4. Composition according to claim 1 , wherein the diameter of the nanoparticles is in a range from 1 to 25 nm.5. Composition according to claim 1 , wherein the metal and/or metal oxide concentration is in a range from 100 ppm to 2000 ppm.6. Composition according to claim 1 , wherein the nanoparticles feature a narrow size distribution.7. Method for preparing a composition according claim 1 , comprising the steps:a) providing a solution of a base in a first solvent;b) dissolving the biopolymer in the solution of step a);c) optionally diluting the solution obtained in step b) to obtain a first solution;d) optionally adjusting the pH of the solution of step b) or c) to a value higher than 9 to achieve a first solution;e) providing a second solution comprising a nanoparticle precursor in a second solvent;f) adding the second solution to the first solution;g) heating the mixture obtained in step f); andh) optionally at least partially removing first and second solvents.8. Method according to claim 7 , wherein the base is an alkali and/or an alkaline earth hydroxide and/or an alkali and/or an alkaline earth alkoxide.9. Method according to claim 7 , wherein the first and the second solvent are at least one polar and protic solvent.10. Method according to claim 7 , wherein steps a) claim 7 , b) claim 7 , c) and/or e) are carried out at 20-30° C.11. Method according to claim 7 , wherein the pH of the first solution after step d) is in a range from 10 to 13.12. Method according to claim 7 , wherein the nanoparticle precursor is a ...

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Номер записи: 16

20-06-2013 дата публикации

MOLDED ARTICLES OF STARCH-POLYMER-WAX-OIL COMPOSITIONS

Номер: US20130158169A1

Автор: Allen William Maxwell, Bond Eric Bryan, Noda Isao

Принадлежит:

Molded articles formed from compositions comprising thermoplastic starch, thermoplastic polymers, and oils, waxes, or combinations thereof are disclosed, where the oil, wax, or combination is dispersed throughout the thermoplastic polymer. 1. A molded article comprising a composition comprising an intimate admixture of(a) a thermoplastic starch;(b) a thermoplastic polymer; and(c) an oil, wax, or combination thereof present in an amount of about 5 wt % to about 40 wt %, based upon the total weight of the composition.2. The molded article of claim 1 , wherein the thermoplastic polymer comprises a polyolefin claim 1 , a polyester claim 1 , a polyamide claim 1 , copolymers thereof claim 1 , or combinations thereof.3. The molded article of claim 2 , wherein the thermoplastic polymer is selected from the group consisting of polypropylene claim 2 , polyethylene claim 2 , polypropylene co-polymer claim 2 , polyethylene co-polymer claim 2 , polyethylene terephthalate claim 2 , polybutylene terepthalate claim 2 , polylactic acid claim 2 , polyhydroxyalkanoates claim 2 , polyamide-6 claim 2 , polyamide-6 claim 2 ,6 claim 2 , and combinations thereof.4. The molded article of claim 1 , wherein the thermoplastic polymer comprises polypropylene.5. The molded article of claim 4 , wherein the polypropylene has a molecular weight of about 20 kDa to about 400 kDa.6. The molded article of claim 4 , wherein the polypropylene has a melt flow index of greater than 5 g/10 min.7. The molded article of claim 6 , wherein the polypropylene has a melt flow index of greater than 10 g/10 min.8. The molded article of claim 1 , comprising about 20 wt % to about 90 wt % of the thermoplastic polymer claim 1 , based upon the total weight of the composition.9. The molded article of claim 8 , comprising about 30 wt % to 70 wt % of the thermoplastic polymer claim 8 , based upon the total weight of the composition.10. The molded article of claim 1 , comprising about 8 wt % to about 30 wt % of the oil ...

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Номер записи: 17

04-07-2013 дата публикации

TOUGHENED POLYESTER BLENDS

Номер: US20130171383A1

Автор: GOHIL RAMESHCHANDRA M.

Принадлежит: E I DU PONT DE NEMOURS AND COMPANY

The properties of melt blends of specific aliphatic-aromatic copolyesters and starch are improved by addition of a combination of polylactic acid, graft copolymers such maleic anhydride grafted polyethylene and maleic anhydride grafted polystyrene, and a hindered phenolic antioxidant. The blends exhibit increased melt strength and maximum draw down ratio versus blends of only aliphatic-aromatic copolyesters and starch. Films made from the blend are compostable and exhibit an attractive combination of mechanical and rheological properties for packaging materials. 1. A composition comprising a melt blend of(a) 50 to 70 wt % copolyester made from monomers comprising 1,3-propanediol, terephthalic acid, and a linear aliphatic dicarboxylic acid, wherein the molar ratio of terephthalic acid to linear aliphatic acid is between 75:25 and 80:20;(b) 15 to 50 wt % starch;(c) 6 to 13 wt % polylactic acid;(d) 0.5 to 5.0 wt % graft copolymer of a polyolefin or a polystyrene; and(e) optionally 0.5 to 5.0 wt % hindered phenol antioxidant.2. The composition of claim 1 , wherein the linear aliphatic dicarboxylic acid is sebacic acid.3. The composition of claim 1 , wherein the graft copolymer is polyethylene-graft-maleic anhydride or polystyrene-graft-maleic anhydride.4. The composition of claim 1 , wherein the hindered phenol antioxidant is 3-(3 claim 1 ,5-di-tert-butyl-4-hydroxyphenyl)propionate.5. The composition of claim 1 , further comprising a nucleating agent.6. The composition of claim 1 , further comprising a chain extender.7. The composition of claim 1 , wherein the starch is a thermoplastic starch.8. The composition of claim 1 , wherein the starch is gelatinized and comprises a polyol plasticizer.9. The composition of claim 8 , wherein the polyol plasticizer is glycerol.10. A film comprising the composition of having an elongation at break greater than 250 percent at 20″/min strain rate claim 1 , and melt strength greater than 450 cN at 160° C.11. An article comprising the ...

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Номер записи: 18

18-07-2013 дата публикации

METHOD FOR IMPROVING THE REMOVAL OF WATER

Номер: US20130180679A1

Автор: Kajanto Isko, Laine Janne, Taipale Tero

Принадлежит: UPM-KYMMENE CORPORATION

The invention relates to a method for improving the removal of water in a composition containing microfibrillated cellulose. According to the invention, a cationic polyelectrolyte that has a low molecular weight and a molecular weight of less than 10000 is provided in the composition containing microfibrillated cellulose. 1. A method for improving the removal of water in a composition containing microfibrillated cellulose , wherein a cationic polyelectrolyte that has a low molecular weight and a molecular weight of less than 10000 is provided in the composition containing microfibrillated cellulose.2. The method according to claim 1 , wherein water is removed from the composition containing microfibrillated cellulose using a predetermined water removal technique.3. The method according to claim 1 , wherein the composition is a fiber mixture containing microfibrillated cellulose.4. The method according to claim 1 , wherein a cationic polyelectrolyte is added to the composition containing microfibrillated cellulose.5. The method according to claim 1 , wherein the cationic polyelectrolyte is first added to the fiber composition and microfibrillated cellulose is then added to the composition.6. The method according to claim 1 , wherein the cationic polyelectrolyte is added to the composition containing microfibrillated cellulose claim 1 , which is then added to the fiber composition.7. The method according to claim 1 , wherein a water removal treatment is performed substantially in one step to remove water from the composition containing microfibrillated cellulose.8. The method according to claim 1 , wherein the water removal treatment is performed in at least two steps to remove water from the composition containing microfibrillated cellulose.9. The method according to claim 1 , wherein the employed cationic polyelectrolyte is a mixture that contains at least one cationic polyelectrolyte that has a low molecular weight and a molecular weight of less than 10000.10. The ...

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Номер записи: 19

18-07-2013 дата публикации

TACKIFIER AND MODIFIED STARCH FORMULATION, SYSTEM AND METHOD

Номер: US20130184381A1

Автор: Bilodeau Rick, Marsden Lloyd

Принадлежит: RANTEC CORPORATION

This disclosure describes formulations, systems and methods for a novel tackifier. The novel tackifier is composed of a modified starch and an acrylamide. 1. A tackifier formulation , the formulation comprising:a modified starch, the modified starch is a vegetable derived starch treated with an enhancer,wherein the enhancer is at least a solution containing a borate salt; andan acrylamide.2. The formulation of wherein the enhancer also includes a surfactant claim 1 , a caustic metal hydroxide claim 1 , a dry organic acid claim 1 , and a dry flow enhancer.3. The formulation of claim 2 , wherein the solution containing the borate salt further includes water and a heavy alcohol;wherein the borate containing salt is a at least one of borax, sodium metaborate, zinc borate, and boric acid;wherein the heavy alcohol is glycerin;wherein the surfactant is a polyethylene glycol;wherein the caustic metal hydroxide is a calcium hydroxide in a dry powder form;wherein the dry organic acid is a fumaric acid blended into the vegetable derived starch until a ratio is reached that provides a pH in a range from about 5.5 to about 7 when the modified starch is added to water; andwherein the dry flow enhancer is a micron sized or fumed silica.4. The formulation of wherein the enhancer also includes at least one of a surfactant claim 1 , a caustic metal hydroxide claim 1 , a dry organic acid claim 1 , and a dry flow enhancer.5. The formulation of wherein the solution containing borate salt is heated to maximize an amount of the borate salt solubilized.6. The formulation of wherein the enhancer is a surfactant.7. The formulation of wherein the enhancer is a caustic metal hydroxide.8. The formulation of wherein the enhancer is a dry organic acid.9. The formulation of wherein the enhancer is a dry flow enhancer.10. The formulation of wherein the acrylamide includes a polyacrylamide in dry powder form.11. The formulation of wherein the tackifier prevents formation of non-dispersed lumps when ...

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Номер записи: 20

25-07-2013 дата публикации

FILM-FORMING COMPOSITION FOR SOFT CAPSULES

Номер: US20130189522A1

Автор: Amemiya Tohru, Fujii Takuma, Nagura Masanori

Принадлежит: R.P. SCHERER TECHNOLOGIES, LLC

Provided herein is a film-forming composition for use in the preparation of a soft capsule, which comprises (a) acid-decomposed waxy corn starch; (b) a gelling agent; and (c) a plasticizer. A soft capsule comprising a shell produced using the film-forming composition disclosed herein has excellent characteristic properties with respect to physical strength, disintegration ability, odor, taste, color and lack of adhesion and also exhibits excellent stability with time. 1. A film-forming composition for use in the preparation of a soft capsule , said film-forming composition comprising:(a) acid-decomposed waxy corn starch;(b) a gelling agent; and(c) a plasticizer.2. The composition as set forth in claim 1 , wherein the acid-decomposed waxy corn starch has a viscosity ranging from about 5 to about 100 mPa·S as determined using a 20% by mass aqueous solution thereof at 80° C.3. The composition as set forth in claim 1 , wherein the gelling agent is carrageenan.4. The composition as set forth in claim 1 , wherein the plasticizer is glycerin claim 1 , sorbitol claim 1 , polyethylene glycol or a mixture thereof.5. The composition as set forth in claim 1 , further comprising (d) a buffering agent.6. The composition as set forth in claim 5 , wherein the buffering agent is a sodium salt claim 5 , a potassium salt or a calcium salt.7. The composition as set forth in claim 1 , wherein the composition is free of any buffering agent.8. A soft capsule shell made using the film-forming composition of .9. A soft capsule comprising the shell of and a capsule-filling material accommodated within the shell. The present invention relates to a film-forming composition for soft capsules suitably used for forming soft capsules and a soft capsule prepared using the composition.Soft capsules have widely been employed in the fields of pharmaceutical preparations, cosmetics and foods. In this respect, gelatin has widely been used as a principal component for constituting the shell of such a ...

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Номер записи: 21

01-08-2013 дата публикации

POLYMER FOAM

Номер: US20130196103A1

Автор: Leufgens Markus, Scheirs John

Принадлежит: TRISTANO PTY LTD

The present invention relates to foam comprising thermoplastic starch, polyolefin, polyolefin wax, ethylene vinyl alkanoate copolymer, and ethylene acrylic copolymer, and also to a method of preparing the same. 1. A foam comprising thermoplastic starch , polyolefin , polyolefin wax , ethylene vinyl alkanoate copolymer , and ethylene acrylic copolymer.2. The foam according to claim 1 , wherein the thermoplastic starch is present in an amount ranging from about 1.5 wt % to about 50 wt % claim 1 , the polyolefin is present in an amount ranging from about 25 wt % to about 97 wt % claim 1 , the polyolefin wax is present in an amount ranging from about 0.05 wt % to about 4 wt % claim 1 , the ethylene vinyl alkanoate copolymer is present in an amount ranging from about 0.4 wt % to about 15 wt % claim 1 , and the ethylene acrylic copolymer is present in an amount ranging from about 0.6 wt % to about 18 wt %.3. The foam according to which has a closed cell structure.4. The foam according to claim 1 , wherein the thermoplastic starch is derived from corn starch claim 1 , potato starch claim 1 , wheat starch claim 1 , soy bean starch claim 1 , tapioca starch claim 1 , hi-amylose starch or combinations thereof.5. The foam according to claim 1 , wherein the polyolefin is selected from low density polyethylene (LDPE) and linear low density polyethylene (LLDPE).6. The foam according to claim 1 , wherein the polyolefin wax is polyethylene wax.7. The foam according to claim 1 , wherein the polyolefin wax has a melt viscosity at 120° C. ranging from about 100 mm/s to about 1200 mm/s as measured according to ASTM 2162.8. The foam according to claim 1 , wherein the ethylene vinyl alkanoate copolymer is selected from ethylene vinyl acetate claim 1 , ethylene vinyl propionate claim 1 , ethylene vinyl butyrate claim 1 , ethylene vinyl isobutyrate claim 1 , ethylene vinyl valerate claim 1 , ethylene vinyl caproate claim 1 , and combinations thereof.9. The foam according to claim 1 , ...

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Номер записи: 22

08-08-2013 дата публикации

Homogeneous Biodegradable Mixture for Shaped-Bodies: Method for Preparing

Номер: US20130199408A1

Автор: Poovarodom Ngamtip

Принадлежит:

The method for preparing a homogeneous biodegradable mixture is described for production of shape-bodies. Reinforce fillers are fibers from various natural sources especially those wastes from varieties of manufacturing. Long thin fibers are obtained by longitudinal abrasion of bamboo waste. Boiling the fibers in water for 20 minutes at pH 8 where supernatant is decanted helps getting rid of chlorophyll. Fibers are further ground to preferable length of 2-4 mm. The treated fibers were mixed with all other ingredients in a rotor, spinning at a speed 1,800-2,000 rpm at ambient temperature for 510 minutes. Starch particles and other ingredients penetrate and mix thoroughly with the fibrous materials. Water is gradually added while kneading to form a perfect dough ready for manufacturing of the desired shape bodies. 1. Method for preparing a homogeneous biodegradable mixture for production of shape-bodies having desirable strength comprises step of dispersing fibrous reinforcing fillers uniformly by dry mixing fibers with all other ingredients using centrifugal force.2. Method for preparing a homogeneous biodegradable mixture for production of shape-bodies of where fibrous reinforcing fillers prepared from bamboo or other grasses of family-Poaceae claim 1 , or Cyperaceae or waste from the wood or food industries and where fibers are obtained by longitudinal abrasion of bamboo.3. Method for preparing a homogeneous biodegradable mixture of where fibrous reinforcing fillers are of 2-4 mm in length.4. Method for preparing a homogeneous biodegradable mixture of where centrifugal force used is 1 claim 1 ,800-2 claim 1 ,000 rpm at ambient temperature for 5-10 minutes.6. Method for preparing a homogeneous biodegradable mixture of where said fibrous reinforcing fillers make up 5-30% of the composition.7. Method for preparing a homogeneous biodegradable mixture of where reinforcing fillers are selected from groups of natural fibrous materials such as fibers from bamboo claim 1 , ...

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Номер записи: 23

08-08-2013 дата публикации

ENCAPSULATED PICOPLATIN

Номер: US20130202690A1

Автор: Breitz Hazel B., Leigh Alistair J., Phillips Angelica F., Procyshyn Christopher A.

Принадлежит: Poniard Pharmaceuticals, Inc.

The invention provides an encapsulated unit dosage form for picoplatin that is adapted for oral administration of the picoplatin containing a substantially dry powder with about 20 to 55 wt % picoplatin in the physical form of a picoplatin particulate wherein an average picoplatin particle diameter is less than about 10 microns. The picoplatin particles are dispersed within the powder of the formulation which includes a substantially water-soluble, water-dispersible, or water-absorbing carbohydrate and an effective amount of up to about 5 wt % of a lubricant. 167.-. (canceled)68. A unit dosage form for picoplatin , adapted for oral administration of the picoplatin , comprising a substantially water-soluble capsule shell , the capsule shell enclosing a formulation comprising a substantially dry powder comprising about 10 to 60 wt % particulate picoplatin , a substantially water-soluble , water-dispersible , or water-absorbing carbohydrate , and an effective amount of up to about 5 wt % of a lubricant.69. The unit dosage form of wherein the particulate picoplatin is of less than about 10 microns average particle diameter claim 68 , and preferably wherein about 90% of the particulate picoplatin has a particle diameter of less than about 5 microns.70. The unit dosage form of wherein the particulate picoplatin is dispersed within substantially every particle of the powder of the formulation and/or wherein the formulation does not comprise an oxidant claim 69 , a metal oxide claim 69 , or a compound comprising a halo claim 69 , ═N(H) claim 69 , —NH claim 69 , or —SH moiety.71. The unit dosage form of wherein the carbohydrate comprises a monosaccharide claim 69 , a disaccharide claim 69 , a sugar alcohol claim 69 , a cellulose claim 69 , a modified cellulose claim 69 , or a mixture thereof.72. The unit dosage form of wherein the capsule shell comprises hard gelatin claim 68 , gelatin/PEG claim 68 , or hydroxypropyl methyl cellulose claim 68 , and preferably wherein the ...

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Номер записи: 24

08-08-2013 дата публикации

GREEN MATERIAL BASED ARTICLE, COMPOSITION, AND METHOD OF PRODUCING SAME

Номер: US20130202843A1

Автор: Agosta Shawn M.

Принадлежит:

Articles of manufacture, compositions of matter, and methods are involved with but are not limited to: substantially uniformly mixing components including at least one or more starch based components, one or more gluten based components, one or more fibrous components, one or more starch agents, and water to produce a mixture; forming said mixture into a predefined shape to produce a formed mixture; treating with curing heat treatment to increase linking within the one or more starch based components involving the one or more starch agents to produce a cured, formed mixture; dehydrating said cured, formed mixture to remove a substantial portion of water to produce a dehydrated, cured, formed mixture; and sealing at least portions of external surfaces to produce a sealed, dehydrated, cured, formed mixture. In addition to the foregoing, other method aspects are described in the claims, drawings, and text forming a part of the present disclosure. 1. An article of manufacture comprising:a formed, substantially dehydrated subsequent to forming, substantially uniform mixture of components at least including one or more starch based components, one or more gluten based components, and one or more fibrous based components, said one or more starch based components having been treated to thereby increase linking within said one or more starch based components prior to dehydration.2. The article of manufacture of wherein a formed claim 1 , substantially dehydrated subsequent to forming claim 1 , substantially uniform mixture of components at least including one or more starch based components claim 1 , one or more gluten based components claim 1 , and one or more fibrous based components claim 1 , said one or more starch based components having been treated to thereby increase linking within said one or more starch based components prior to dehydration comprises:the formed, substantially dehydrated subsequent to forming, substantially uniform mixture of components at least ...

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Номер записи: 25

05-09-2013 дата публикации

STARCH-BASED THERMOPLASTIC COMPOSITES

Номер: US20130231421A1

Автор: Chang Chih-jen, Chang Hsieh-Yung, Chen Chien-Ming, Chung Yao-Chu, Liao Cheng-Feng, Liao Sheng-Ju

Принадлежит: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE

In an embodiment, a starch-based thermoplastic composite is provided. The starch-based thermoplastic composite includes enzyme-degraded thermoplastic starch (TPS) having a debranching rate of 40-90%, polycarbonate (PC) and acrylonitrile butadiene styrene (ABS), wherein the polycarbonate (PC) has a weight ratio of 15-60% in the starch-based thermoplastic composite. The starch-based thermoplastic composite further includes an impact modifier and a compatibilizer. 1. A starch-based thermoplastic composite , comprising:enzyme-degraded thermoplastic starch (TPS) having a debranching rate of 40-90%;polycarbonate (PC), wherein the polycarbonate (PC) has a weight ratio of 15-60% in the starch-based thermoplastic composite; andacrylonitrile butadiene styrene (ABS).2. The starch-based thermoplastic composite as claimed in claim 1 , wherein the enzyme-degraded thermoplastic starch (TPS) has a debranching rate of 40-60%.3. The starch-based thermoplastic composite as claimed in claim 1 , wherein the enzyme-degraded thermoplastic starch (TPS) has a weight ratio of 10-70% in the starch-based thermoplastic composite.4. The starch-based thermoplastic composite as claimed in claim 1 , wherein the enzyme-degraded thermoplastic starch (TPS) has a weight ratio of 10-35% in the starch-based thermoplastic composite.5. The starch-based thermoplastic composite as claimed in claim 1 , wherein 95% of the enzyme-degraded thermoplastic starch (TPS) has a particle size less than 1.5 μm.6. The starch-based thermoplastic composite as claimed in claim 1 , wherein the polycarbonate (PC) has a weight ratio of 30-45% in the starch-based thermoplastic composite.7. The starch-based thermoplastic composite as claimed in claim 1 , wherein the acrylonitrile butadiene styrene (ABS) has a weight ratio of 15-60% in the starch-based thermoplastic composite.8. The starch-based thermoplastic composite as claimed in claim 1 , wherein the acrylonitrile butadiene styrene (ABS) has a weight ratio of 30-45% in the ...

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Номер записи: 26

10-10-2013 дата публикации

Artificial snow and method for making same

Номер: US20130264508A1

Автор: Elizabeth Quee, John Quee

Принадлежит: Thomas FX Group Inc

A non-toxic, non-static, environmentally benign artificial snow product is made by extruding a mixture of starch, polyvinyl alcohol, hydrogenated soy flakes and talc to form an extruded starch product and processing the extruded starch product into snow flake like fragments. The snow flake like fragments may be sorted by size. Colorant may be added to yield artificial snow flakes in various festive colors.

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Номер записи: 27

17-10-2013 дата публикации

Modeling compounds and methods of making and using the same

Номер: US20130274377A1

Автор: Doane, Hall Tania, JR. Linwood E., Tsimberg Lev

Принадлежит: HASBRO, INC.

Modeling compounds and methods for making the same are described. The modeling compounds, in some embodiments, comprise about 20% to about 40% by weight starch-based binder, and about 0.15% to about 1.2% by weight microspheres dispersed throughout the compounds. In some embodiments, the modeling compound further comprises vinylpyrrolidone polymers. 1. A modeling composition comprising:(a) about 30% to about 60% by weight water;(b) about 20% to about 40% by weight starch-based binder;(c) about 2.0% to about 8.0% by weight lubricant;(d) about 0.5% to about 4.0% by weight surfactant;(e) about 5% to about 20% by weight salt;(f) about 0.1% to about 1% by weight preservative;(g) about 0.5% to about 10% by weight retrogradation inhibitor;(h) about 0.15% to about 1.2% by weight microspheres(i) about 0.5% to about 8% by weight vinylpyrrolidone polymers;(j) 0% to about 15% polyol;(k) 0% to about 1% by weight hardener;(l) 0% to about 0.5% by weight fragrance; and(m) 0% to about 5% by weight colorant.2. The modeling composition of claim 1 , wherein the polyols are selected form the group consisting of glycerine claim 1 , sorbitol claim 1 , propylene glycol and some combination thereof.3. The modeling composition of claim 1 , wherein the microspheres are selected from the group consisting of pre-expanded microspheres claim 1 , glass microspheres claim 1 , and some combination thereof.4. The modeling composition of claim 1 , wherein the microspheres are hollow microspheres claim 1 , solid microspheres or some combination thereof.5. The modeling composition of claim 1 , wherein the microspheres have a size ranging from about 20 microns to about 130 microns.6. The modeling composition of claim 1 , wherein the salt is selected from the group consisting of sodium chloride claim 1 , calcium chloride claim 1 , potassium chloride and some combination thereof.7. The modeling composition of claim 1 , wherein the lubricant is selected from the group consisting of mineral oil claim 1 , ...

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Номер записи: 28

24-10-2013 дата публикации

FIBROUS ELEMENTS COMPRISING FAST WETTING SURFACTANTS AND METHODS FOR MAKING SAME

Номер: US20130280508A1

Автор: Heinzman Stephen Wayne, James Michael David, WOODS Brooke Marie

Принадлежит: The Procter & Gamble Company

Fibrous elements, such as filaments and/or fibers, and more particularly to fibrous elements that contain a fast wetting surfactant, fibrous structures made therefrom, and methods for making same are provided. 1. A fibrous element comprising a blend comprising a fibrous element-forming polymer and a fast wetting surfactant.2. The fibrous element according to wherein the fibrous element-forming polymer comprises a hydroxyl polymer.3. The fibrous element according to wherein the hydroxyl polymer comprises a polysaccharide.4. The fibrous element according to wherein the fibrous element-forming polymer is selected from the group consisting of: polyvinyl alcohol claim 1 , polyvinyl alcohol derivatives claim 1 , polyvinyl alcohol copolymers claim 1 , gums claim 1 , arabinans claim 1 , galactans claim 1 , proteins claim 1 , and mixtures thereof.5. The fibrous element according to wherein the blend comprises two or more fibrous element-forming polymers.6. The fibrous element according to wherein the fast wetting surfactant is selected from the group consisting of: anionic surfactants claim 1 , cationic surfactants claim 1 , nonionic surfactants claim 1 , zwitterionic surfactants claim 1 , and mixtures thereof.7. The fibrous element according to wherein the fast wetting surfactant comprises a sulfosuccinate surfactant.8. The fibrous element according to wherein the blend further comprises a non-hydroxyl polymer selected from the group consisting of: polyacrylamide and its derivatives; polyacrylic acid claim 1 , polymethacrylic acid claim 1 , and their esters; polyethyleneimine; copolymers made from mixtures of monomers of the aforementioned polymers; and mixtures thereof.9. The fibrous element according to wherein the non-hydroxyl polymer comprises polyacrylamide.10. The fibrous element according to wherein the fibrous element comprises a filament.11. A fibrous structure comprising a plurality of fibrous elements according to .12. The fibrous structure according to wherein ...

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Номер записи: 29

31-10-2013 дата публикации

STARCH COMPOSITION FOR USE IN PAPER MANUFACTURE

Номер: US20130284389A1

Автор: Roux Rudy, Voigt Andreas

Принадлежит: Cargill, Incorporated

The starch composition comprises a cationic, cross-linked starch that is partly swollen and partly gelatinized. It has a gelatinization coefficient gT smaller than 0.7 with T the jet cooking temperature. The starch composition suitably comprises a wheat starch or a blend of a wheat starch and another starch, for instance a root or tuber starch. 115.-. (canceled)17. The starch composition of claim 16 , wherein the starch composition has a gelatinization coefficient gT smaller than 0.7 claim 16 , the gelatinization coefficient being defined according to the formula gT=(ηref−ηjet claim 16 , T)/(ηref−ηfinal) with ηref being the Brookfield viscosity after batch cooking at 96° C.; ηjet claim 16 , T being the sample Brookfield viscosity after jet cooking at temperature T; and ηfinal being 40 mPas claim 16 , wherein all Brookfield viscosities are measured at 3% dry solids claim 16 , 100 rpm claim 16 , spindle 2 and 50° C.18. The composition of claim 16 , wherein the starch composition has a gelatinization coefficient gT smaller than 0.6 claim 16 , the gelatinization coefficient being defined according to the formula gT=(ηref−ηjet claim 16 , T)/(ηref−ηfinal) with ηref being the Brookfield viscosity after batch cooking at 96° C.; ηjet claim 16 , T being the sample Brookfield viscosity after jet cooking at temperature T of 120° C.; and ηfinal being 40 mPas claim 16 , wherein all Brookfield viscosities are measured at 3% dry solids claim 16 , 100 rpm claim 16 , spindle 2 and 50° C.19. The composition of claim 16 , wherein the first starch comprises a wheat starch.20. The composition of claim 16 , wherein the first starch comprises a wheat starch claim 16 , wherein the wheat starch has been cross-linked with a diether cross-linker.21. The composition of claim 16 , wherein the first starch comprises a wheat starch claim 16 , wherein the wheat starch has been cross-linked with a diether cross-linker applied in an amount of 60 to 500 ppm.22. The composition of claim 16 , wherein ...

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Номер записи: 30

31-10-2013 дата публикации

Bulk Enteric Capsule Shells

Номер: US20130287840A1

Автор: Benameur Hassan, Cade Dominique Nicolas, Schreiber Sophie

Принадлежит: Capsugel Belgium NV

The present disclosure relates to aqueous compositions for use in the manufacture of capsule shells endowed with bulk enteric properties. The present disclosure also relates, in part, to aqueous dispersions suitable for the implementation of said manufacturing process, and to enteric capsule shells and hard capsules obtained therewith. 1. An aqueous composition for the manufacture of enteric hard capsule shells , comprising:(a) an aqueous dispersion of non-salified cellulose acetate phthalate (CAP), said CAP being present in an amount ranging from about 10% to about 40% by weight of the total weight of said aqueous composition;(b) at least one processing aid present in an amount ranging from about 4% to about 20% by weight of the total weight of said aqueous composition, wherein said at least one processing aid is selected from polyoxyethylene- polyoxypropylene- polyoxyethylene tri-block polymers or mixtures thereof, having an average molecular weight ranging from about 1000 to about 20000 and a polyoxyethylene ratio ranging from about 10% to about 85%; and(c) water.2. The composition according to claim 1 , wherein the total amount of the CAP and the at least one processing aid range from about 14.9% to about 50% combined claim 1 , by weight of the total weight of the composition.3. The composition according to claim 1 , wherein the CAP is in the form of finely divided solid particles having an average diameter ranging from about 0.1 to about 10 microns.4. The composition according to claim 1 , wherein the at least one processing aid is selected from poloxamers or mixtures thereof.5. The composition according to claim 1 , further comprising at least one pharmaceutically acceptable or food acceptable colouring agent.6. The composition according to claim 1 , further comprising at least one film forming aid.7. The composition according to claim 6 , wherein the at least one film forming aid is selected from thickening agents claim 6 , structuring agents claim 6 , ...

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Номер записи: 31

31-10-2013 дата публикации

Hard Capsules

Номер: US20130287842A1

Автор: Dominique Nicolas Cade, Takahisa Takubo

Принадлежит: Capsugel Belgium NV

Publicly available pullulan hard capsule shells present certain drawbacks, notably a non fully satisfactory shell mechanical strength (i.e. shell brittleness) at shell low LOD. Improving this property is a particularly desirable goal for pullulan hard capsule shells. The present invention solves this and other objects by providing new hard pullulan capsule shells and capsules comprising (I) moisture, (II) a mono-, di-, and oligosaccharides free pullulan and (III) a setting system. Also provided are an aqueous composition and a dip-molding manufacturing method for the manufacture of such shells and capsules.

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Номер записи: 32

31-10-2013 дата публикации

Abuse resistant capsules

Номер: US20130287843A1

Автор: Victor Morrison Young

Принадлежит: MW Encap Ltd

Hard shell capsules filled with a pharmaceutical medicament and at least one modifier, selected to prevent abuse of the medicament are described. The modifier may have a high melting point, and therefore melt at a temperature too high to inject or be insoluble in liquid, having a density less than 1, to prevent “spiking” of drinks. The modifier may also be a waxy substance which cannot be crushed, a viscosity modifier, a dye or a taste modifier.

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Номер записи: 33

07-11-2013 дата публикации

Bulk enteric capsule shells

Номер: US20130295188A1

Автор: Dominique Nicolas Cade, Hugues Straub

Принадлежит: Capsugel France SAS

The present disclosure relates to aqueous composition comprising hydroxypropyl methyl cellulose acetate succinate (HPMCAS) polymer dispersed in water, wherein the dispersed polymer is partially neutralized with at least one alkaline material. The instant disclosure also relates to compositions for use in methods of making capsule shells endowed with bulk enteric properties. The present disclosure also relates to capsules made according with the compositions and methods of the present disclosure.

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Номер записи: 34

14-11-2013 дата публикации

EPOXIDIZED FATTY ACID ALKYL ESTERS AS FLEXIBILIZERS FOR POLY(LACTIC ACID)

Номер: US20130303653A1

Автор: Donnelly Zuzanna

Принадлежит: Arkema Inc.

A composition containing (a) at least one biodegradable/biorenewable thermoplastic material that includes poly(lactic acid) (PLA); and (b) at least one plasticizer that includes an epoxidized fatty acid alkyl ester is provided. In some embodiments, the epoxidized fatty acid alkyl ester is methyl epoxy soyate. It was found that epoxidized fatty acid alkyl esters impart a reduction in tensile modulus in compositions containing PLA. The compositions may be formed into films, such as those used in food packaging. A method that includes extruding a composition comprising PLA and at least one epoxidized fatty acid alkyl ester is provided. 1. A composition comprising:(a) at least one biodegradable/biorenewable thermoplastic material comprising poly(lactic acid); and(b) at least one plasticizer comprising an epoxidized fatty acid alkyl ester.2. The composition of claim 1 , wherein the epoxidized fatty acid alkyl ester is an epoxidized fatty acid methyl ester.3. The composition of claim 1 , wherein the epoxidized fatty acid alkyl ester is methyl epoxy soyate.4. The composition of claim 1 , wherein the epoxidized fatty acid alkyl ester is an epoxidized fatty acid alkyl ester of a vegetable oil.5. The composition of claim 1 , wherein the epoxidized fatty acid alkyl ester is selected from the group consisting of epoxidized biodiesel and epoxidized derivatives of biodiesel.6. The composition of claim 1 , wherein the epoxidized fatty acid alkyl ester is an alkyl ester of an epoxidized C-Cfatty acid.7. The composition of claim 1 , wherein the epoxidized fatty acid alkyl ester is an epoxidized castor oil-based fatty acid alkyl ester.8. The composition of claim 1 , wherein the plasticizer comprises a blend of multiple epoxidized fatty acid alkyl esters.9. The composition of claim 1 , wherein the plasticizer further comprises an epoxidized oil.10. The composition of claim 9 , wherein the epoxidized oil comprises epoxidized soybean oil.11. The composition of claim 1 , wherein the ...

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Номер записи: 35

21-11-2013 дата публикации

FORMULATIONS COMPRISING EXINE SHELLS

Номер: US20130309298A1

Автор: ATKIN Stephen Lawrence, BECKETT Stephen Thomas, DIEGO-TABOADA Alberto, MACKENZIE Grahame

Принадлежит:

A formulation containing an active substance encapsulated within an exine shell of a naturally occurring spore, together with a protective additive which is also encapsulated within the exine shell. 137-. (canceled)38. A formulation comprising an active substance encapsulated within an exine shell of a naturally occurring spore , together with a protective additive which is also encapsulated within the exine shell , wherein the active substance comprises a hydrophilic and/or hydrolysable and/or acid-labile substance and/or a proteinaceous material; a carbohydrate; a lipid; a nucleoside , nucleotide or nucleic acid; a vitamin or co-vitamin; an essential fatty acid; an essential mineral or mineral-containing substance; a glyconutrient; a phytonutrient; a nutritional agent; or a micro-organism; and/or a substance selected from peptides , enzymes , probiotics and prebiotics; and the protective additive is a solid or semi-solid at room temperature.39. The formulation of claim 38 , wherein the active substance comprises a hydrophilic and/or hydrolysable and/or acid-labile substance and/or a substance selected from peptides claim 38 , enzymes claim 38 , probiotics and prebiotics.40. The formulation of claim 38 , wherein the active substance comprises a substance selected from peptides claim 38 , enzymes claim 38 , probiotics and prebiotics.41. The formulation of claim 38 , wherein the protective additive is water insoluble.42. The formulation of claim 38 , wherein the protective additive comprises one or more lipids or materials having a lipid component.43. The formulation of claim 42 , wherein the protective additive comprises a lipid or material having a lipid component selected from the group consisting of a butter or other solid fat; a fatty acid having a C11 to C22 carbon chain length; a fatty acid ester; a fatty acid amide; a phospholipid; a glycolipid; a lipid sulphate; a lipid sulphonate; a monoglyceride; a diglyceride claim 42 , and a triglyceride.44. The ...

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Номер записи: 36

28-11-2013 дата публикации

METHOD FOR TREATING A PATIENT VIA PHOTODYNAMIC THERAPY COMPRISING A MACROMOLECULAR CAPSULE

Номер: US20130315989A1

Автор: Baek Kangkyun, Hota Raghunandan, JUNG Hyuntae, KIM Kimoon, Kim Youngkook, PARK Kyeng Min, Yun Gyeongwon

Принадлежит: POSTECH ACADEMY-INDUSTRY FOUNDATION

A composition for photodynamic therapy including a polymer capsule having a diameter of about nm to about nm synthesized by copolymerization of a flat aromatic compound represented by Formula (see the specification) and an organic compound represented by Formula (see the specification). 3. The method of claim 1 , wherein the compound of Formula 1 has a C-Cethenyl (—CH═CH) or ethynyl (—C≡CH) group.4. The method of claim 1 , wherein the compound of Formula 2 is selected from the group consisting of 1 claim 1 ,8-octanedithiol claim 1 , 3 claim 1 ,6-dioxa-1 claim 1 ,8-octanedithiol claim 1 , pentaerythritol tetrakis(3-mercaptopropionate) claim 1 , trimethylolpropane tri(3-mercaptopropionate) claim 1 , and a combination thereof.5. The method of claim 1 , wherein the photodynamic therapy is for the treatment of liver cancer claim 1 , lung cancer claim 1 , uterine cancer claim 1 , skin cancer claim 1 , bronchogenic cancer claim 1 , brain cancer claim 1 , or gastric cancer.6. The method of claim 1 , wherein a pharmacologically active agent is encapsulated into an internal part of the polymer capsule.7. The method of claim 6 , wherein the pharmacologically active agent is an anti-cancer agent.8. The method of claim 7 , wherein the anti-cancer agent is selected from the group consisting of doxorubicin claim 7 , daunorubicin claim 7 , paclitaxel claim 7 , docetaxel claim 7 , Taxol claim 7 , and Glivec.9. The method of claim 6 , wherein the pharmacologically active agent is a drug for the treatment of a side effect of photodynamic therapy. This application is a continuation application of U.S. patent application Ser. No. 13/264,427, filed Oct. 14, 2011 (now pending), the disclosure of which is herein incorporated by reference in its entirety. The U.S. patent application Ser. No. 13/264,427 is a national entry of International Application No. PCT/KR2009/006032, filed on Oct. 20, 2009, which claims priority to Korean Application No. 10-2009-0032959 filed on Apr. 15, 2009, the ...

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Номер записи: 37

02-01-2014 дата публикации

CARBOXYMETHYL STARCH AND CHITOSAN POLYELECTROLYTE COMPLEXES

Номер: US20140005280A1

Автор: Assaad Elias, MATEESCU Mircea-Alexandru

Принадлежит: 4413261 Canada Inc. (Spencer Canada)

A carboxymethyl starch and chitosan polyelectrolyte complex is provided. A carrier comprising this polyelectrolyte complex along with a solid oral dosage form comprising this polyelectrolyte complex are also provided. A method of manufacturing the polyelectrolyte complex is also provided. 1. A carboxymethyl starch and chitosan polyelectrolyte complex , wherein the carboxymethyl starch is a high amylose carboxymethyl starch.2. The polyelectrolyte complex of claim 1 , wherein the carboxymethyl starch is a carboxymethyl starch salt.3. The polyelectrolyte complex of claim 2 , wherein the carboxymethyl starch salt is sodium carboxymethyl starch or potassium carboxymethyl starch.4. (canceled)5. The polyelectrolyte complex of claim 2 , wherein the carboxymethyl starch salt is partially protonated.6. The polyelectrolyte complex of claim 1 , wherein the degree of substitution of the carboxymethyl starch is between about 0.03 and about 2.7. The polyelectrolyte complex of claim 6 , wherein the degree of substitution of the carboxymethyl starch is about 0.14.8. The polyelectrolyte complex of claim 1 , wherein the degree of deacetylation of the chitosan is about 65% or more.9. The polyelectrolyte complex of claim 8 , wherein the degree of deacetylation of the chitosan is about 80%.10. The polyelectrolyte complex of claim 1 , wherein the molecular weight of the chitosan is about 100 kDa or more.11. The polyelectrolyte complex of claim 10 , wherein the molecular weight of the chitosan is between about 400 and about 700 kDa.12. The polyelectrolyte complex of claim 11 , wherein the molecular weight of the chitosan is about 700 kDa.13. The polyelectrolyte complex of claim 1 , wherein —NH groups of the chitosan and —COO groups of the carboxymethyl starch are present in a (—NH:—COO) ratio ranging from about to about 1:0.5 to about 0.5:1.14. The polyelectrolyte complex of claim 13 , wherein the —NH groups of the chitosan and the —COO groups of the carboxymethyl starch are present in a 1 ...

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Номер записи: 38

02-01-2014 дата публикации

METHOD FOR PRODUCING PLASTICIZED STARCH BY USING 1,3-PROPANEDIOL AND RESULTING COMPOSITION

Номер: US20140005308A1

Автор: Macedo Galvaing Sophie

Принадлежит: METABOLIC EXPLORER

The present invention concerns a method for manufacturing a starch-based plasticized composition comprising starch and a plasticizer said plasticizer comprising 1,3-propanediol (PDO). The invention also concerns a plasticized material comprising the plasticized starch composition of the invention and a polymer. 114-. (canceled)15. A method for manufacturing a starch-based plasticized composition comprising the following:a) mixing a solid composition comprising a starch and a plasticizer composition comprising 1,3-propanediol, andb) obtaining a plasticized composition by reacting the mixture of (a).16. The method of claim 15 , wherein the solid composition in (a) contains at least 45 weight % of starch.17. The method of claim 15 , wherein the solid composition in (a) contains at least 60 weight % of starch.18. The method of claim 15 , wherein the plasticizer composition comprises 1 claim 15 ,3-propanediol and at least one other plasticizer.19. The method of claim 18 , wherein the amount of 1 claim 18 ,3-propanediol in the plasticizer composition ranges from 25 to 100% by weight of the total plasticizer composition.20. The method of claim 18 , wherein the amount of 1 claim 18 ,3-propanediol in the plasticizer composition ranges from 50 to 100% by weight of the total plasticizer composition.21. The method of claim 15 , wherein the plasticizer comprises a mixture of 1 claim 15 ,3-propanediol and sorbitol.22. The method of claim 15 , wherein further comprising adding at least one cross-linking agent selected from:diisocyanates optionally comprising methylenediphenyl-diisocyanate (MDI), toluene-diisocyanate (TDI), naphthalene-diisocyanate (NDI), hexamethylen-diisocyanate (HDMI) and lysine-diisocyanate (LDI), andorganic diacids optionally comprising succinic acid, adipic acid, glutaric acid, oxalic acid, malonic acid, maleic acid and corresponding anhydrides.23. The method of claim 15 , wherein (b) is realised by heating the mixture of (a).24. The method of claim 15 , ...

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Номер записи: 39

09-01-2014 дата публикации

POLYOLEFIN COMPOSITIONS COMPRISING BIO-BASED STARCH MATERIALS

Номер: US20140011921A1

Автор: Bagrodia Shriram, Bash Thomas F., Kelly William E., Scheer Frederic

Принадлежит: Cereplast, Inc,

Polyolefin compositions and methods of making and using the polyolefin compositions are provided. In a general embodiment, the present disclosure provides a composition comprising a polyolefin, a compatibilizer, a starch and a plasticizer. 1. A method of making a polyolefin composition , the method comprising:blending a polyolefin, a compatibilizer, a starch and a plasticizer to form a mixture.2. The method of comprising extruding the blended mixture to form an extrudate.3. The method of comprising shaping the extrudate to form an article selected from the group consisting of toys claim 2 , computer casing claim 2 , DVDs claim 2 , toiletries claim 2 , combs claim 2 , consumer products claim 2 , cellular phone casings claim 2 , bags claim 2 , foam material products claim 2 , packaging claim 2 , automobile parts claim 2 , cookware and combinations thereof.4. The method of claim 3 , wherein the articles are made by a process selected from the group consisting of injection molding claim 3 , thermoforming claim 3 , film blowing claim 3 , stretch blow molding claim 3 , extrusion blow molding claim 3 , extrusion coatings claim 3 , profile extrusion claim 3 , film extrusion claim 3 , cast films claim 3 , cast products and combinations thereof.5. The method of claim 1 , wherein the polyolefin is selected from the group consisting of polyethylene claim 1 , polypropylene claim 1 , polybutene and combinations thereof.6. The method of claim 5 , wherein the polyethylene is selected from the group consisting of low density polyethylene claim 5 , high density polyethylene claim 5 , linear low density polyethylene and combinations thereof.7. The method of claim 1 , wherein the compatibilizer is selected from the group consisting of maleic anhydride grafted polypropylene claim 1 , maleic anhydride grafted polyethylene claim 1 , maleic anhydride grafted polybutene and combinations thereof.8. The method of claim 1 , wherein the compatibilizer comprises maleated polypropylene with a ...

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Номер записи: 40

23-01-2014 дата публикации

Water-Sensitive Biodegradable Film

Номер: US20140023806A1

Автор: Shi Bo, Wang James H.

Принадлежит: KIMBERLY-CLARK WORLDWIDE, INC.

A film that is biodegradable and water-sensitive (e.g., water-soluble, water-dispersible, etc.) in that it loses its integrity over time in the presence of water is provided. More specifically, the film contains a combination of a biodegradable polyester and a water-sensitive thermoplastic starch. The desired water-sensitive attributes of film may be achieved in the present invention by selectively controlling a variety of aspects of the film construction, such as the nature of the components employed, the relative amount of each component, the manner in which the film is formed, and so forth. 1. A water-sensitive biodegradable film , the film comprising:from about 1 wt. % to about 20 wt. % of at least one biodegradable polyester, wherein the biodegradable polyester includes at least one biodegradable aliphatic-aromatic copolyester that has a melting point of from about 50° C. to about 180° C. and a glass transition temperature of about 0° C. or less; andfrom about 60 wt. % to about 99 wt. % of at least one water-sensitive thermoplastic starch component, wherein the thermoplastic starch component comprises from about 60 wt. % to about 80 wt. % of at least one water-soluble, chemically modified starch, from about 0.5 wt. % to about 4 wt. % of at least one surfactant, and from about 20 wt. % to about 40 wt. % of at least one plasticizer, wherein the water-soluble chemically modified starch comprises a starch ester, a hydroxyalkyl starch, or a combination thereof;wherein the film has a thickness of about 50 micrometers or less and exhibits visible disintegration when sloshed in tap water for 30 seconds at a frequency of 3.5 sloshes per second, the film further exhibiting a dry ultimate tensile strength of from about 20 to about 50 Megapascals in the machine direction and a dry modulus of elasticity of from about 400 to about 1000 Megapascals in the machine direction.24-. (canceled)5. The water-sensitive biodegradable film of claim 1 , wherein the biodegradable ...

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Номер записи: 41

20-02-2014 дата публикации

SUSTAINED-RELEASE NANOPARTICLE COMPOSITIONS AND METHODS USING THE SAME

Номер: US20140050798A1

Автор: Labhasetwar Vinod D., Reddy Maram K., Sahoo Sanjeeb K.

Принадлежит: Board of Regents of the Univ. of Nebraska by and Behalf of the University of Nebraska Medical Cente

The present invention is a composition composed of a therapeutic agent encapsulated in a copolymer of an N-alkylacrylamide, a vinyl monomer, and a polyethylene glycol (PEG) conjugate and a method for using the same in the treatment or prevention of a disease or condition. 13.-. (canceled)4. A sustained-release nanoparticle composition comprising a therapeutic agent and a cross-linked copolymer of an N-alkylacrylamide , a vinyl monomer selected from the group consisting of a vinyl alcohol , a vinyl ether , a vinyl ester , vinyl pyrrolidone , or a combination of said vinyl monomers , and a polyethylene glycol (PEG) conjugate in nanoparticle form , wherein the weight per weight ratio of the N-alkylacrylamide , vinyl monomer and (PEG) conjugate is 70-90:9-20:1-10 , said therapeutic agent being encapsulated in said copolymer.5. The sustained-release nanoparticle composition of claim 4 , wherein said therapeutic agent is selected from the group consisting of antibiotics claim 4 , antirestenotics claim 4 , anti-proliferative agents claim 4 , anti-neoplastic agents claim 4 , chemotherapeutic agents claim 4 , cardiovascular agents claim 4 , anti-inflammatory agents claim 4 , immunosuppressive agents claim 4 , anti-apoptotic and anti-tissue damage agents.6. The sustained-release nanoparticle composition of claim 4 , wherein said therapeutic agent comprises an anti-proliferative agent.7. The sustained-release nanoparticle composition of claim 4 , wherein said ratio is 80:15:5.8. The sustained-release nanoparticle composition of claim 4 , wherein said nanoparticles have an average diameter in the range of 20 nm to 100 nm as measured by transmission electron microscopy.9. The sustained-release nanoparticle composition of claim 4 , wherein said therapeutic agent is an anti-apoptotic agent.10. The sustained-release nanoparticle composition of claim 9 , wherein said anti-apoptotic agent is selected from the group consisting of galectin-3 claim 9 , (-) deprenyl claim 9 , rapamycin ...

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Номер записи: 42

06-03-2014 дата публикации

COMPOSITION FOR A STARCH CONTAINER, STARCH CONTAINER USING SAME, AND METHOD FOR MANUFACTURING THE STARCH CONTAINER

Номер: US20140061089A1

Автор: Kim Heon Moo, Kim Kang Soo

Принадлежит: YOUL CHON CHEMICAL CO., LTD.

Provided is a composition for a starch container, comprising: 20 to 60 weight % of an undenatured starch; 5 to 30 weight % of a pulp fiber powder; 0.1 to 2 weight % of a photocatalyst; 0.5 to 5 weight % of a release agent; and 0.01 to 5 weight % of a capsule type blowing agent preparations; and the remainder being a solvent. Also provided is a starch container using the composition. The above-described composition of the present invention may be used not only as a material for a disposable container which has improved blowing property, and which is lightweight and has improved moldability, but also as a material for an eco-friendly starch container having eco-friendly characteristics. 1. A composition for a starch container , comprising: 20-60 wt % of an unmodified starch; 5-30 wt % of a pulp fiber powder; 0.1-2 wt % of a photocatalyst; 0.5-5 wt % of a release agent; 0.01-5 wt % of a capsule-type blowing agent; and a solvent as the remainder.2. The composition for a starch container according to claim 1 , wherein the capsule-type blowing agent comprises: an inner part comprising a hydrocarbon as a blowing agent; and an outer part comprising a thermoplastic material.3. The composition for a starch container according to claim 2 , wherein the hydrocarbon is a material that is gasified at or below the softening point of the thermoplastic material and the thermoplastic material is a material that can endure a pressure of 300 kg/cmor higher.4. The composition for a starch container according to claim 3 , wherein the hydrocarbon is selected from a group consisting of propane claim 3 , propylene claim 3 , butene claim 3 , n-butane claim 3 , isobutane claim 3 , isopentane claim 3 , neopentane claim 3 , n-pentane claim 3 , n-hexane claim 3 , isohexane claim 3 , heptane claim 3 , octane claim 3 , nonane and decane.5. The composition for a starch container according to claim 3 , wherein the thermoplastic material is selected from a group consisting of a nitrile-based monomer ...

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Номер записи: 43

20-03-2014 дата публикации

POLYMERIC STRUCTURES AND METHOD FOR MAKING SAME

Номер: US20140079914A1

Автор: CABELL David William, KECK Fred J., Loebker David Warren, Mackey Larry Neil, RICHARDS Mark Ryah

Принадлежит: The Procter & Gamble Company

Polymeric structures, methods for making same, fibrous structures comprising same and fibrous product incorporating same are provided. 1. A fibrous structure comprising a fiber comprising a PVOH and a hydroxyl polymer starch , wherein the fibrous structure exhibits a dry lint score of less than about 50.2. The fibrous structure according to wherein the fibrous structure comprises two or more fibers that are associated with one another.3. The fibrous structure according to wherein the fibrous structure comprises two or more regions that exhibit different values of a common intensive property relative to each other.4. The fibrous structure according to wherein the common intensive property is selected from the group consisting of: density claim 3 , basis weight claim 3 , caliper claim 3 , substrate thickness claim 3 , elevation claim 3 , opacity claim 3 , crepe frequency and mixtures thereof.5. A fibrous product comprising one or more fibrous structures according to .6. The fibrous structure according to wherein the fibrous structure exhibits a wet pill area of less than about 4%.7. The fibrous structure according to wherein the fiber further comprises a crosslinking system comprising a crosslinking agent claim 1 , wherein the hydroxyl polymer starch is crosslinked by the crosslinking agent such that the fiber as a whole does not exhibit a melting point.8. The fibrous structure according to wherein the fiber exhibits a fiber diameter of less than about 50 μm.9. The fibrous structure according to claim 1 , wherein the fibrous structure comprises two or more fibers at least one of which comprises a fiber comprising PVOH and a hydroxyl polymer starch claim 1 , wherein the fibrous structure comprises a first region comprising associated fibers and a second region comprising non-associated fibers.10. The fibrous structure according to wherein the fibrous structure comprises two or more regions that exhibit different values of a common intensive property relative to each ...

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Номер записи: 44

20-03-2014 дата публикации

Process for Improving the Flow Rate of an Aqueous Dispersion

Номер: US20140080944A1

Автор: Andermann, Bluemle Michael J., Broecher Markus, JR. Lawrence, Peltier Jeffrey

Принадлежит: Hercules Inc

A process for improving the flow rate of an aqueous dispersion which comprises adding a natural polymer to said aqueous system and then adding a synthetic polymer to the aqueous system. 1. A process for improving the flow rate of an aqueous dispersion comprising(a) adding a natural polymer to the aqueous dispersion, and(b) then adding a synthetic polymer to the aqueous dispersion, wherein the natural polymer and the synthetic polymer is an amount effective to increase the flow rate of the aqueous dispersion.2. The process of wherein the natural polymer is a polysaccharide.3. The process of wherein the polysaccharide is a dextran.4. The process of wherein the synthetic polymer is selected from the group consisting of water soluble anionic polymers claim 3 , cationic polymers claim 3 , amphoteric polymers claim 3 , nonionic polymers claim 3 , and mixtures thereof.5. The process of wherein the synthetic polymer is an anionic polymer.6. The process of wherein the anionic polymer is selected from the group consisting of copolymers derived from 2-acrylamido 2-methylpropane sulfonic acid claim 5 , copolymers of acrylic acid and acrylamide claim 5 , homopolymers of acrylic acid claim 5 , homopolymers of acrylamide claim 5 , and combinations thereof.7. The process of wherein the anionic polymer comprises a copolymer of sodium acrylate and acrylamide or a copolymer of acrylic acid and acrylamide.8. The process of wherein the pH of the anionic polymer is about 5 to about 10.9. The process of wherein Mw of the dextran is about 5 claim 5 ,000 to about 40 claim 5 ,000 claim 5 ,0000.10. The process of wherein Mw of the anionic polymer is about 500 claim 9 ,000 to about 25 claim 9 ,000 claim 9 ,000.11. The process of wherein the PDI of the dextran is about 1.0 to about 0.12. The process of wherein weight ratio of natural polymer and synthetic polymer is a ratio effective to increase the flow rate of the aqueous dispersion.13. The process of wherein weight ratio of natural polymer ...

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Номер записи: 45

20-03-2014 дата публикации

Process for Improving the Rheological Properties of an Aqueous Dispersion

Номер: US20140080945A1

Автор: Jeffrey H. Peltier, Lawrence J. ANDERMANN, Jr., Markus Broecher, Michael James Bluemle

Принадлежит: HERCULES LLC

A process for improving the rheological properties of an aqueous dispersion comprising adding a rheology modifier to the aqueous dispersion, and then adding a water soluble synthetic polymer flocculant to the aqueous dispersion. The rheology modifier may be selected from the group consisting of natural polymers, semi-natural polymers, synthetic materials and combinations thereof. The water soluble synthetic polymer flocculant may be selected from the group consisting of water soluble anionic polymers, cationic polymers, amphoteric polymers, nonionic polymers, and combinations thereof.

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Номер записи: 46

27-03-2014 дата публикации

Biodegradable material

Номер: US20140087106A1

Автор: Daniel Arnillas Perez, Maria Begona Gomis Gomis, Paul William Law, Tony Longdon

Принадлежит: Biome Bioplastics Ltd

A thermoplastic, biodegradable polymer blend showing high surface energy and good adhesion without the need for pre-treatment consists of starch in the range 10% to 60% by weight of the polymer blend, one or more further carrier polymers in the range 40% to 90% by weight of the polymer blend and one or more process aids in the range 0% to 0.5% by weight of the polymer blend. The polymer blends typically have a surface energy after processing of at least 40 mN/m.

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Номер записи: 47

27-03-2014 дата публикации

Hydroxypropyl Methyl Cellulose Hard Capsules and Process of Manufacture

Номер: US20140088202A1

Автор: Cade Dominique Nicolas, He Xiongwei David

Принадлежит: Capsugel Belgium NV

A composition for manufacture of hard hydroxypropyl methyl cellulose capsules comprising a film forming material of hydroxypropyl methyl cellulose having a methoxy content of 27.0-30.0% (w/w), and a hydroxypropoxy content of 4.0-7.5% and as a 2% weight solution, a viscosity of 3.5-6.0 cPs at 20° C., dipping compositions, process for manufacture of hard hydroxypropyl methyl cellulose capsules according to a dip coating process and hard capsule shells. 1. An aqueous composition for manufacture of hard capsules , comprising , [{'sup': +', '++', '++, '(i) the group consisting of at least one cation selected from the group consisting of K+, Na+, Li+, NH4, Ca, Mg and mixtures thereof and'}, '(ii) at least one gelling agent selected from the group consisting of alginates, agar gum, guar gum, locust bean gum (carob), carrageenan, tara gum, gum Arabic, ghatti gum, khaya grandifolia gum, tragancanth gum, karaya gum, pectin, arabian (araban), xanthan, gellan gum, konjac mannan, galactomannan, funoran, and mixtures thereof., 'in an aqueous solvent, 15-25% by weight, based on the total weight of the aqueous composition, of a hydroxypropyl methyl cellulose 2906 (HPMC 2906) having a methoxy content of 27.0-30.0% (w/w), a hydroxypropoxy content of 4.0-7.5% (w/w) and a viscosity of 3.5-6.0 cPs as a 2% weight solution in water at 20° C., and less than 1% of a gelling system selected from'}2. The composition according to claim 1 , wherein the hydroxypropyl methyl cellulose has a viscosity of 4.0-5.0 cPs as a 2% weight solution in water at 20° C.3. The composition according to claim 1 , wherein 17-23% by weight based on the total weight of the aqueous composition claim 1 , is hydroxypropyl methyl cellulose.4. The composition according to claim 1 , wherein the aqueous solvent is water.513-. (canceled)14. A hydroxypropyl methyl cellulose hard capsule shell containing a hydroxypropyl methyl cellulose having a methoxy content of 27.0-30.0% (w/w) claim 1 , a hydroxypropoxy content of 4.0-7. ...

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Номер записи: 48

10-04-2014 дата публикации

POLYMER COMPOSITION FOR MANUFACTURNING BIODEGRADABLE ARTICLES AND PROCESS THEREOF

Номер: US20140096861A1

Автор: Abhyankar Chandrashekhar Ramchandra, Banerjee Mrinal Kanti

Принадлежит: Essel Propack Limited

The present disclosure provides a bio-degradable polymer composition comprising: 30% to 50% (w/w) of an extrusion grade bio-degradable polymer; and 50% to 70% (w/w) of an injection molding grade bio-degradable polymer. The bio-degradable polymer composition of the present disclosure is used for manufacturing bio-degradable article, such as bio-degradable tubes. The present disclosure further provides a process for manufacturing of bio-degradable tube. These and other features, aspects, and advantages of the present subject matter will become better understood with reference to the following description and appended claims. This summary is provided to introduce a selection of concepts in a simplified form. 1. A biodegradable polymer composition , comprising:(A) 30% to 50% (w/w) of an extrusion grade bio-degradable polymer; and(B) 50% to 70% (w/w) of an injection molding grade bio-degradable polymer.2. The biodegradable polymer composition as recited in claim 1 , further comprising:(C) a biopolymer additive, in an amount of 4% to 10% (w/w) of the weight of the composition.3. The biodegradable polymer composition as recited in claim 1 , wherein both the extrusion grade biodegradable polymer and the injection grade bio-degradable polymer are food grade biopolymers.4. The biodegradable polymer composition as recited in claim 1 , wherein the bio-degradable polymer is selected from polylactic acid (PLA) claim 1 , polyhydroxy alkanoate (PHA) claim 1 , polyglycolide (PGA) claim 1 , polycaprolactone (PCL) claim 1 , polysaccharide claim 1 , and combinations thereof.5. The biodegradable polymer composition as recited in claim 1 , comprising:(A1) 35% to 45% (w/w) of an extrusion grade bio-degradable polymer; and(B1) 55% to 65% (w/w) of an injection molding grade bio-degradable polymer.6. A bio-degradable article made of the polymer composition as recited in .7. The bio-degradable article as recited in claim 6 , wherein the article is a tube.8. A process of manufacturing the a ...

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Номер записи: 49

10-04-2014 дата публикации

CONTINUOUS METHOD FOR PRODUCING NANOPARTICLES AND NANOPARTICLES OBTAINED BY MEANS OF SAID METHOD

Номер: US20140099377A1

Автор: Casanova Yepes Herley, Higuita Gonzalez Lina Paola

Принадлежит: UNIVERSIDAD DE ANTIOQUIA

The invention relates to a continuous method for producing inorganic or organic nanoparticles having multiple nuclei functionalised with proteins, using a T-type reactor that operates at high pressure, the primary particles that form the nuclei of the nanoparticles being smaller than 10 nm and said primary particles being immersed in a proteinaceous matrix that forms the nanoparticle in sizes of between 30 nm and 500 nm. The invention also relates to the nanoparticles produced by means of said method. 1. A nanoparticles producing process characterized in that is a continuous process and comprises the following stages:a) Provide two different water soluble precursor solutions of organic or inorganic salts prepared at pH above 6, and a temperature between 2° C. and 50° C., containing protein and optionally solubilized active ingredient in one or two precursor solutions;b) Mixing precursor solutions in a quick and continuous way using a high pressure homogenizer having a T-type reactor operating at a pressure between 10 MPa and 400 MPa with temperature control between 2° C., and 95° C.; andc) Receive recently formed nanoparticles in a container that may contain water or aqueous diluents which prevents aggregation of nanoparticles.2. The process of producing nanoparticles according to characterized in that the water soluble claim 1 , organic or inorganic precursor salts are selected from the group consisting of soluble magnesium salts claim 1 , soluble calcium salts claim 1 , soluble barium salts claim 1 , strontium soluble salts claim 1 , soluble carbonates salts claim 1 , soluble phosphates salts claim 1 , soluble silicates salts claim 1 , soluble sulfates salts claim 1 , soluble oxalates salts claim 1 , soluble citrates salts claim 1 , and mixtures thereof.3. The process of producing nanoparticles according to characterized in that proteins as dispersants claim 1 , stabilizers and functionalizing agents of nanoparticles are selected from the groups consisting of milk ...

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Номер записи: 50

10-04-2014 дата публикации

Thermoplastic elastomer compositions having biorenewable content

Номер: US20140100311A1

Автор: Alain Perreault, Basil D. Favis, Kevin Cai, Prashant A. BHADANE, Ryszard Brzoskowski, Yundong Wang

Принадлежит: CERESTECH Inc, Teknor Apex Co

Thermoplastic elastomer compositions, in particular derived from one or more styrenic block copolymers wherein at least one styrenic block copolymer comprises a controlled distribution copolymer block including a conjugated diene and a mono alkenyl arene, a plurality of biorenewable materials, preferably a softener and one or more synergistic additives such as a polar polymer; a synergistic block copolymer such as a relatively high molecular weight styrenic block copolymer; and/or filler. Numerous desirable articles can be formed from the compositions. Processes for preparing the compositions and articles are disclosed.

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Номер записи: 51

07-01-2021 дата публикации

DEFINED DOSE CANNABIS POD

Номер: US20210000789A1

Автор: HARRISON Nancy, Wagner Christopher

Принадлежит:

pods comprising a defined dose of and methods for making said pods. This method comprises milling or grinding the , passing it through a mesh or sieve, determining the desired amount of cannabinoid, and encapsulating the dose in a textile. 216.-. (canceled)18CannabisCannabisCannabis sativa, Cannabis indica, Cannabis ruderalis. The pod of wherein the plant material preparation includes material derived from one or more plants from a species selected from the group consisting of claim 17 , and hybrids thereof.19CannabisCannabis indica.. The pod of wherein the species is20CannabisCannabis. The pod of wherein the plant material preparation includes material prepared from inflorescence.21. The pod of further comprising one or more additives selected from among terpenes claim 17 , terpenoids claim 17 , pod stabilizers claim 17 , humectants claim 17 , vaporization aids claim 17 , fillers and flavours.22. The pod of wherein the amount of THC is less than a psychotropic dose.23. The pod of wherein the amount of THCA is less than 1.0 mg.24. The pod of comprising:THCA in an amount between 1-165 mg,THC in an amount less than 1.0 mg; andCBDA in an amount between 0.1-70 mg,and having total mass 100-500 mg.25. The pod of comprising:THCA in an amount less than 5.0 mg,THC in an amount between 1-135 mg; andCBD in an amount between 0.1-70 mg,and having total mass 100-500 mg.26. The pod of comprising:THCA in an amount less than 1.0 mg,THC in an amount less than 1.0 mg; andCBD in an amount between 5-90 mg,and having total mass 100-500 mg.27CannabisCannabis. The pod of wherein one or more of the plant material preparation is prepared from one or more plants selected from the group consisting of Charlotte's Web and other high CBDA claim 17 , low THCA plant varieties.28. The pod of wherein the textile contains no synthetic polymer.29. The pod of wherein the textile is organically sourced.30. The pod of wherein the pod comprises no chemical adhesive.31. The pod of claim 17 , wherein the pod ...

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Номер записи: 52

03-01-2019 дата публикации

ENTERIC CAPSULE

Номер: US20190000768A1

Автор: Hayano Akihiko, Shimokawa Yoshiyuki

Принадлежит:

There are manufactured an enteric capsule comprising: a seamless capsule consisting of a capsule fill and a shell layer; and an enteric coating layer on the shell layer, the enteric coating layer comprising one selected from a methacrylic acid-based polymer, polyvinyl acetate phthalate, organic acid ester of hydroxypropylmethylcellulose, carboxymethylethylcellulose, and cellulose acetate phthalate; and an enteric seamless capsule further comprising a subcoating layer between the shell layer of the seamless capsule and the enteric coating layer, the subcoating layer consisting of hydroxypropylcellulose and the like. The enteric seamless capsule has acid resistance and also enables controlled dissolution for each application site in the body. 1. An enteric capsule comprising:a seamless capsule consisting of a capsule fill and a shell layer; andan enteric coating layer on the shell layer, the enteric coating layer comprising one or more selected from the group consisting of a methacrylic acid-based polymer, polyvinyl acetate phthalate, organic acid ester of hydroxypropylmethylcellulose, carboxymethylethylcellulose, and cellulose acetate phthalate.2. The enteric capsule according to claim 1 , wherein the shell layer of the seamless capsule comprises gelatin and glycerin.3. The enteric capsule according to claim 1 , wherein the enteric coating layer comprises 30 to 80 parts by mass of one or more selected from the group consisting of a methacrylic acid-based polymer claim 1 , polyvinyl acetate phthalate claim 1 , and cellulose acetate phthalate based on 100 parts by mass of the enteric coating layer.4. The enteric capsule according to claim 1 , wherein the enteric coating layer comprises 50 to 100 parts by mass of one or more selected from the group consisting of organic acid ester of hydroxypropylmethylcellulose claim 1 , carboxymethylethylcellulose claim 1 , and cellulose acetate phthalate based on 100 parts by mass of the enteric coating layer.5. The enteric capsule ...

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Номер записи: 53

04-01-2018 дата публикации

PHARMACEUTICAL COMPOSITIONS FOR COLON-SPECIFIC DELIVERY

Номер: US20180000740A1

Автор: Li Lianli

Принадлежит:

Disclosed are pharmaceutical particulates which release a pharmaceutical compound into the colon following oral administration. A particulate comprises a core comprising a pharmaceutical compound, an inner coating surrounding the core, wherein the inner coating comprises a pharmaceutically acceptable polysaccharide that is susceptible to enzymatic digestion by one or more enzymes present colonic microflora, and an outer coating surrounding the inner coating, wherein the outer coating comprises a polymer which is stable at upper gastrointestinal pH but can dissolve at pH>6. The core of a particulate can further comprise an excipient such as a diluent, a binder, a disintegrant, a lubricant, a glidant or a combination thereof. Particulates can comprise pharmaceutical compounds for treating colonic diseases such as infection, ulcerative colitis, colon cancer, and Crohn's disease. 1. A pharmaceutical composition comprising particulates comprising:a. a core comprising metronidazole and one or more pharmaceutically acceptable excipients;b. an inner coating surrounding the core comprising a polysaccharide enzyme substrate polymer which is dissolved by enzymes in the colon; andc. an outer coating surrounding the inner coating comprising a polymethacrylate which dissolves at pH≧6.2. The particulate as recited in wherein said core is formulated for immediate release.3. The particulate as recited in wherein said core dissolves at aqueous medium in less than about 60 minutes.4. The particulate as recited in claim 1 , wherein said particulates have a distribution of particle sizes in a range of about 1 mm to about 3 mm.5. The particulate as recited in claim 1 , wherein the one or more pharmaceutically acceptable excipients is selected from the group consisting of a diluent claim 1 , a binder claim 1 , a disintegrant claim 1 , a lubricant claim 1 , a glidant and a combination thereof.6. The particulate as recited in claim 1 , wherein the polysaccharide is selected from the group ...

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Номер записи: 54

02-01-2020 дата публикации

PROBIOTIC COMPOSITIONS AND DOSAGE FORMS, AND METHODS FOR PREPARING AND USING THE SAME

Номер: US20200000732A1

Автор: Rao K. Gnaneshwar

Принадлежит:

The invention relates to probiotic dosage forms, probiotic compositions contained within the dosage forms, and compositions used for sealing the probiotic dosage forms, as well as methods for preparing and using the probiotic dosage forms. 18-. (canceled)9. A probiotic dosage form comprising:a sealed, two piece capsule comprised of a plant-based cellulose,{'sub': 'w', 'a composition within the sealed capsule, the composition comprising a probiotic organism, a carrier agent having a water activity (a) level at or below 0.5, and from about 1 to about 4 weight percent of a suspending agent, wherein the weight percent is based on the total weight of the composition; and'}an anaerobic inert gas within the sealed capsule;wherein the seal is formed by applying a liquid composition comprising a plant-based cellulose externally of the two piece capsule.10. The probiotic dosage form according to claim 9 , wherein the plant-based cellulose of the two piece capsule is the same as the plant-based cellulose that is present within the seal.11. The probiotic dosage form according to claim 9 , wherein the plant-based cellulose of the two piece capsule is different from the plant-based cellulose that is present within the seal.12. The probiotic dosage form according to claim 9 , wherein the plant-based cellulose of the two piece capsule and the plant-based cellulose present within the seal are independently selected from the group consisting of alkyl-substituted cellulose ethers claim 9 , hydroxyalkyl-substituted cellulose ethers claim 9 , alkylcelluloses claim 9 , hydroxyalkylcelluloses claim 9 , hydroxyalkylalkylcelluloses claim 9 , carboxyalkylcelluloses claim 9 , carboxyalkyl-alkylcelluloses claim 9 , and mixtures thereof.13. (canceled)14. The probiotic dosage form according to claim 9 , wherein each capsule piece comprises a composition consisting of HPMC claim 9 , carrageenan claim 9 , potassium acetate claim 9 , and water.15. The probiotic dosage form according to claim 9 , ...

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Номер записи: 55

03-01-2019 дата публикации

Modified cellulose fibers and preparation method

Номер: US20190002669A1

Автор: Frank-Jürgen METHNER, Niklas Ole Brandt, Thomas Kunz

Принадлежит: TECHNISCHE UNIVERSITAET BERLIN

The invention relates to a method for the preparation of modified cellulose fibers for artificial clarification of active haze substances from liquids. In addition, the invention relates to a modified cellulose fiber obtained by the method according to the invention for artificial clarification of active haze substances from a liquid, and to auxiliary filtering means containing one or more of the modified cellulose fibers.

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Номер записи: 56

13-01-2022 дата публикации

CAPSULE FORMULATION

Номер: US20220008296A1

Автор: Hutchison Keith, Takubo Takahisa

Принадлежит: Capsugel Belgium NV

[Technical Problem] A problem of the present invention is, in one aspect, to provide a capsule formulation including an active ingredient and the like that may deteriorate upon contacting an acid, wherein the capsule formulation makes it possible not to deteriorate the active ingredient and the like by a gastric acid which enters into a capsule film. 1. A method for protecting an active ingredient from an acid , comprising:dispersing or dissolving the active ingredient in an oil that is acceptable for pharmaceuticals or foods and which (i) protects the active ingredient from the acid and (ii) has a specific gravity of 0.95 or lower; andencapsulating the oil comprising the active ingredient in an acid resistant hard capsule comprising a water-soluble film forming polymer and gellan gum.2. The method of claim 1 , wherein the acid resistant hard capsule has a body portion and a cap portion and the method further comprises sealing the acid resistant hard capsule at a fitted part of body portion and the cap portion using a band sealing solution.3. The method of claim 1 , wherein the active ingredient is a pharmaceutical claim 1 , a dietary supplement claim 1 , a peptide claim 1 , an amino acid claim 1 , a protein claim 1 , a glycoprotein claim 1 , an enzyme fermented food claim 1 , an enzyme claim 1 , a coenzyme claim 1 , a vitamin claim 1 , a living microbe claim 1 , a plant extract claim 1 , propolis claim 1 , or any combination thereof.4. The method of claim 1 , wherein the oil has a specific gravity of 0.94 or lower.5. The method of claim 1 , wherein the oil is a plant oil claim 1 , an animal oil claim 1 , a fish oil claim 1 , or a mineral oil.6. The method of claim 1 , wherein the oil is a medium-chain triglyceride claim 1 , safflower oil claim 1 , olive oil claim 1 , soybean oil claim 1 , linseed oil claim 1 , rice germ oil claim 1 , wheat germ oil claim 1 , coconut oil claim 1 , corn oil claim 1 , cottonseed oil claim 1 , palm oil claim 1 , palm nucleus oil claim ...

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Номер записи: 57

03-01-2019 дата публикации

A method for producing a sizing agent composition, a sizing agent composition and use thereof

Номер: US20190003126A1

Автор: Lepo Anneli, Turkki Tarja, Turunen Elsi

Принадлежит: KEMIRA OYJ

The present invention relates to a sizing agent composition comprising starch, lignosulfonate and poly(alkyl acrylate), poly(alkyl (meth)acrylate), a mixture of poly(alkyl acrylate) and poly(alkyl methacrylate) or a copolymer of alkyl acrylate and alkyl (meth)acrylate. The present invention further relates to a method for preparing the sizing agent composition, and use of the sizing agent composition for sizing paper, paper products or board. 1. A sizing agent composition comprising starch , lignosulfonate and poly(alkyl acrylate) or poly(alkyl methacrylate) or mixture of poly(alkyl acrylate) and poly(alkyl methacrylate) or a copolymer of alkyl acrylate and alkyl methacrylate.2. The sizing agent composition according to claim 1 , wherein the starch is anionic starch claim 1 , cationic starch or amphoteric starch claim 1 , preferably anionic starch cationic starch claim 1 , more preferably anionic starch.3. The sizing agent composition according to claim 1 , wherein the starch has a molecular weight Mof at most 10000 g/mol claim 1 , preferably from 300 g/mol to 10000 claim 1 , more preferably from 500 g/mol to 5000 g/mol.4. The sizing agent composition according to claim 1 , wherein the poly(alkyl acrylate) is selected from a group consisting of polymers obtainable by free radical copolymerization of at least one ethylenically unsaturated monomer of C-C-alkyl acrylate claim 1 , preferably the poly(alkyl acrylate) is poly(tert-butylacrylate); and{'sub': 1', '8, 'the poly(alkyl methacrylate) is selected from a group consisting of polymers obtainable by free radical copolymerization of at least one ethylenically unsaturated monomer of C-C-alkyl (meth)acrylate, preferably the poly(alkyl methacrylate) is poly(tert-butyl methacrylate).'}5. The sizing agent composition according to claim 1 , wherein the copolymer of alkyl acrylate and alkyl methacrylate is a copolymer of ethylenically unsaturated monomer of C-C-alkyl acrylate and ethylenically unsaturated monomer of C-C- ...

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Номер записи: 58

10-01-2019 дата публикации

DUAL RELEASE DOSAGE FORM CAPSULE AND METHODS, DEVICES AND SYSTEMS FOR MAKING SAME

Номер: US20190008781A1

Автор: PUCKETT John

Принадлежит: Gel Cap Technologies, LLC

Provided is a dual dosage form capsule, methods for producing and systems for making the same, which can provide dual release of the two dosages. The dual dosage form capsule has a first capsule member containing a first fill material and a second capsule member containing a second fill material. A band couples the first capsule member to the second capsule member and forms a third chamber defined by an inner surface of the band and each cap of the capsule members. An aperture allows fluid into the third chamber causing the band to at least partially dissolve so that the caps of the capsule members are exposed. The caps of the capsule members can dissolve at the same or different rates to control the timing of the release of the first and second fill materials and hence an active ingredient included within the fill material. 1. A dual dosage capsule , comprising:a first capsule member comprising a first fill material;a second capsule member comprising a second fill material; anda band having a first end connected to the first capsule member to sealingly contain the first fill material in the first capsule member and an opposing second end connected to the second capsule member to sealingly contain the second fill material in the second capsule member, thereby defining an internal chamber between the first capsule member and the second capsule member within the band;wherein the band comprises one or more apertures therethrough radially oriented relative to a longitudinal axis of the capsule, thereby placing the internal chamber in fluid communication with the environment outside the capsule.2. The dual dosage capsule of claim 1 , wherein the first end of the annular band is open and has an end of the first capsule member received therein and the second end of the annular band is open and has an end of the second capsule member received therein claim 1 , or the first end of the annular band is received in an open end of the first capsule member and the second end of ...

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Номер записи: 59

10-01-2019 дата публикации

POWDER COMPONENT-CONTAINING SEAMLESS CAPSULE AND METHOD FOR MANUFACTURING SAME

Номер: US20190008782A1

Автор: Nakano Osami

Принадлежит:

An object of the present invention is to increase an amount of a powder component dispersed in a content in a seamless capsule. The present invention relates to a seamless capsule including a content and an outer shell enclosing the content adjacently to the content, and provides a powder component-containing seamless capsule in which the content is a suspension prepared by dispersing a powder component, which is poorly soluble in water and oil, in an oil component or a hydrophilic component, the content has a specific gravity of 1 or more, and a difference (Δd=d−d) between the specific gravity (d) of the content and a specific gravity (d) of the outer shell is within the range of −0.15 to +0.05 and a method for manufacturing the same. 115-. (canceled)16. A powder component-containing seamless capsule comprising:a content; andan outer shell enclosing the content adjacently to the content,{'sub': B', 'A', 'A', 'B, 'wherein the content is a suspension prepared by dispersing a powder component that is poorly soluble in water and oil, in an oil component or a hydrophilic component, the content has a specific gravity of 1 or more, and a difference (Δd=d−d) between the specific gravity (d) of the content and a specific gravity (d) of the outer shell is within a range of −0.15 to +0.05.'}17. The powder component-containing seamless capsule according to claim 16 , wherein one or more outermost layers enclosing the outer shell are provided on an outer side of the outer shell.18. The powder component-containing seamless capsule according to claim 16 , wherein the specific gravity of the outer shell is adjusted by adding a specific gravity regulator.19. The powder component-containing seamless capsule according to claim 18 , wherein the specific gravity regulator is selected from the group consisting of inorganic or organic powder having a particle density of 0.9 to 6.0 g/cmand a mixture thereof.20. The powder component-containing seamless capsule according to claim 16 , ...

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Номер записи: 60

08-01-2015 дата публикации

Bulk Enteric Capsule Shells

Номер: US20150010620A1

Автор: Benameur Hassan, Cade Dominique Nicolas, Schreiber Sophie

Принадлежит:

The present disclosure relates to aqueous compositions for use in the manufacture of capsule shells endowed with bulk enteric properties. The present disclosure also relates, in part, to aqueous dispersions suitable for the implementation of said manufacturing process, and to enteric capsule shells and hard capsules obtained therewith. 1. An aqueous composition for the manufacture of enteric hard capsule shells , comprising:(a) an aqueous dispersion of non-salified cellulose acetate phthalate (CAP), said CAP being present in an amount ranging from about 10% to about 40% by weight of the total weight of said aqueous composition;(b) at least one processing aid present in an amount ranging from about 4% to about 20% by weight of the total weight of said aqueous composition, wherein said at least one processing aid is selected from polyoxyethylene-polyoxypropylene-polyoxyethylene tri-block polymers or mixtures thereof, having an average molecular weight ranging from about 1000 to about 20000 and a polyoxyethylene ratio ranging from about 10% to about 85%; and(c) water.2. The composition according to claim 1 , wherein the total amount of the CAP and the at least one processing aid range from about 14.9% to about 50% combined claim 1 , by weight of the total weight of the composition.3. The composition according to claim 1 , wherein the CAP is in the form of finely divided solid particles having an average diameter ranging from about 0.1 to about 10 microns.4. The composition according to claim 1 , wherein the at least one processing aid is selected from poloxamers or mixtures thereof.5. The composition according to claim 1 , further comprising at least one pharmaceutically acceptable or food acceptable colouring agent.6. The composition according to claim 1 , further comprising at least one film forming aid.7. The composition according to claim 6 , wherein the at least one film forming aid is selected from thickening agents claim 6 , structuring agents claim 6 , ...

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Номер записи: 61

10-01-2019 дата публикации

MICELLAR NANOCOMPLEX

Номер: US20190008830A1

Автор: BAE Ki Hyun, CHUNG Joo Eun, Kurisawa Motoichi, LEE Esther, Nunnarpas Yongvongsoontorn, TAN Min-Han, Ying Jackie Y.

Принадлежит:

The present invention relates to micellar nanocomplexes and a method of forming the same. The micellar nanocomplex comprises a micelle and an agent encapsulated within said micelle, where the micelle comprises a polymer-flavonoid conjugate, wherein said polymer is bonded to the B ring of said flavonoid. The micellar nanocomplex may have useful applications as a drug-delivery system. 124-. (canceled)25. A polymer-flavonoid conjugate comprising a polymer bonded to the B ring of a flavonoid.26. The polymer-flavonoid conjugate of claim 25 , wherein said polymer is selected from the group consisting of a polysaccharide claim 25 , polyacrylamide claim 25 , poly(N-isopropylacrylamide) claim 25 , poly(oxazoline) claim 25 , polyethylenimine claim 25 , poly(acrylic acid) claim 25 , polymethacrylate claim 25 , poly(ethylene glycol) claim 25 , poly(ethylene oxide) claim 25 , poly(vinyl alcohol) claim 25 , poly(vinylpyrrolidinone) claim 25 , polyethers claim 25 , poly(allylamine) claim 25 , polyanhydrides claim 25 , poly(β-amino ester) claim 25 , poly(butylene succinate) claim 25 , polycaprolactone claim 25 , polycarbonate claim 25 , polydioxanone claim 25 , poly(glycerol) claim 25 , polyglycolic acid claim 25 , poly(3-hydroxypropionic acid) claim 25 , poly(2-hydroxyethyl methacrylate) claim 25 , poly(N-(2-hydroxypropyl)methacrylamide) claim 25 , polylactic acid claim 25 , poly(lactic-co-glycolic acid) claim 25 , poly(ortho esters) claim 25 , poly(2-oxazoline) claim 25 , poly(sebacic acid) claim 25 , poly(terephthalate-co-phosphate) and copolymers thereof.27. The polymer-flavonoid conjugate of claim 25 , wherein said flavonoid is selected from the group consisting of (−)-epicatechin claim 25 , (+)-epicatechin claim 25 , (−)-catechin claim 25 , (+)-catechin claim 25 , epicatechin gallate claim 25 , epigallocatechin claim 25 , epigallocatechin gallate claim 25 , Fisetinidol claim 25 , Gallocatechin claim 25 , Gallocatechin gallate claim 25 , Mesquitol and Robinetinidol claim 25 , ...

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Номер записи: 62

10-01-2019 дата публикации

PHARMACEUTICAL FORMULATIONS OF A HIF HYDROXYLASE INHIBITOR

Номер: US20190008846A1

Автор: Conca David, Flippin Lee Allen, Leigh Scott David, Witschi Claudia, Wright Lee Robert

Принадлежит:

The present disclosure relates to pharmaceutical formulations of [(4-hydroxy-1-methyl-7-phenoxy-isoquinoline-3-carbonyl)-amino]-acetic acid and methods of use thereof. 1. A pharmaceutical composition formulated to prevent or reduce the photodegradation of an active ingredient [(4-hydroxy-1-methyl-7-phenoxy-isoquinoline-3-carbonyl)-amino]-acetic acid , the composition comprising the active ingredient [(4-hydroxy-1-methyl-7-phenoxy-isoquinoline-3-carbonyl)-amino]-acetic acid , and an effective amount of a photostabilizing agent , which photostabilizing agent:i) prevents the transmission of light at a wavelength range of between about 200 nm and 550 nm; andii) is admixed with the active ingredient, or provided in an outer coating or shell surrounding the active ingredient, such that the composition upon exposure to light contains less than about 0.2% w/w photodegradation product of [(4-hydroxy-1-methyl-7-phenoxy-isoquinoline-3-carbonyl)-amino]-acetic acid relative to the amount of [(4-hydroxy-1-methyl-7-phenoxy-isoquinoline-3-carbonyl)-amino]-acetic acid.2. The pharmaceutical composition of claim 1 , wherein the photostabilizing agent comprises titanium dioxide and at least one additional dye selected from the group consisting of a red dye claim 1 , a yellow dye claim 1 , and a combination of a red dye and a yellow dye.3. The pharmaceutical composition of claim 1 , wherein the photostabilizing agent comprises titanium dioxide and at least one additional dye selected from the group consisting of iron oxide red claim 1 , Allura Red AC claim 1 , Allura Red AC Aluminum Lake claim 1 , iron oxide yellow claim 1 , Sunset Yellow FCF claim 1 , and Sunset Yellow FCF Aluminum Lake claim 1 , or a combination thereof.4. The pharmaceutical composition of claim 1 , comprising from about 20 mg to about 200 mg of [(4-hydroxy-1-methyl-7-phenoxy-isoquinoline-3-carbonyl)-amino]-acetic acid.5. The pharmaceutical composition of claim 1 , comprising about 20 mg claim 1 , about 50 mg claim 1 ...

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Номер записи: 63

27-01-2022 дата публикации

DOUGH-LIKE PLAY COMPOUNDS, KITS, AND METHODS OF MAKING AND USING THE SAME

Номер: US20220025184A1

Автор: Osnato Jeffrey, Williams Dexter

Принадлежит:

The present disclosure relates generally to compositions which form a dough-like moldable play compound when combined with a solvent, as well as kits, and methods of making and using the same. More particularly, it relates to compositions, kits, and methods of making and using a powder composition which forms a dough-like moldable play compound with a solvent. In a preferred embodiment, the solvent comprises water. 1. A powder pre-mix composition , comprising:between 5 wt. % and about 80 wt. % of a binding agent; wherein the binding agent comprises wheat flour, corn starch, or a combination thereof;a salt; andbetween 2 wt. % and 25 wt. % of a humectant; wherein the humectant comprises mineral oil, glycerin, sorbitol, or a combination thereof;wherein the powder pre-mix composition forms a moldable play compound when combined with a solvent.2. The composition of claim 1 , wherein the binding agent comprises wheat flour and corn starch in a ratio of from about 2:1 to about 1:2.3. The composition of claim 1 , wherein the salt comprises sodium chloride and is present in the composition in an amount of from about 25 wt-% to about 60 wt-%.4. The composition of claim 1 , wherein the composition further comprises a silica and/or silicone comprising polydimethyl siloxane claim 1 , silica claim 1 , dimethicone/vinyl dimethicone cross polymer and silica claim 1 , or a combination thereof claim 1 , and is present in the composition in an amount of from about 2 wt-% to about 40 wt-%.5. The composition of claim 1 , wherein the binding agent is further treated with one or more additional humectants comprising glycerin claim 1 , mineral oil claim 1 , or a combination thereof.6. The composition of claim 1 , wherein the composition further comprises from about 0.5 wt-% to about 7 wt-% of tartaric acid or a salt thereof.7. The composition of claim 1 , wherein the composition is substantially free of water.8. The composition of claim 1 , wherein the solvent is water.9. The composition ...

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Номер записи: 64

11-01-2018 дата публикации

BIODEGRADABLE PELLETS FOAMED BY IRRADIATION

Номер: US20180009970A1

Автор: Bastioli Catia, Lombi Roberto, Nicolini Matteo, Turati Daniele

Принадлежит:

This invention relates to biodegradable starch-based pellets which foamable by irradiation, which are particularly suitable for the manufacture of foam articles, characterised in that they have a porous structure with a low porous external skin. This invention also relates to foam articles obtained from these. 1. A process for the preparation of foamed articles , said process comprising irradiating biodegradable low density , self-sealing pellets , said pellets comprising starch essentially free of native crystallinity which does not have endothermic gelatinisation peaks associated with a ΔH of more than 0.4 J/g of dry starch when analysed by differential scanning calorimetry in a hermetic capsule with a water/dry starch ratio of 4 , said pellets being characterized by:a porous internal structure having void area greater than 15% with respect to the area of the cross-section of the pellet;a mean equivalent diameter of pores less than 100 microns andan external skin with pores in number less than 80% with respect to the internal structure having a mean equivalent diameter lower or equal to the mean equivalent diameter of the pores of the internal structure.2. The process according to claim 1 , wherein said pellets comprise at least a further polymer of synthetic or natural origin.4. The process according to claim 2 , wherein said further polymer of natural origin is selected from the group consisting of cellulose claim 2 , lignin claim 2 , proteins claim 2 , phospholipids claim 2 , casein claim 2 , polysaccharides claim 2 , natural gums claim 2 , rosinic acid claim 2 , dextrins claim 2 , their mixtures and derivatives thereof.5. The process according to claim 2 , wherein said further polymer of synthetic origin is selected from the group consisting of:thermoplastic polymers comprising homopolymers and copolymers of linear or branched aliphatic hydroxyacid having C2-C24 main chain, their lactons and lactides as well as their copolymers with aliphatic polyesters of the ...

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Номер записи: 65

03-02-2022 дата публикации

MODIFIED RELEASE DOXYCYCLINE COMPOSITION

Номер: US20220031714A1

Автор: Baheti Ankit, Padhi Bijay Kumar, Raghuvanshi Rajeev Singh

Принадлежит:

Doxycycline formulations with a reduced food effect are disclosed. Particularly disclosed are modified release formulations which can be administered once a day and exhibit a reduced food effect. Methods of treating inflammatory conductions such as rosacea or inflammatory symptoms such as the papules and pustules of rosacea or acne vulgaris are also disclosed. 111-. (canceled)12. A method of treating inflammatory rosacea or an inflammatory symptom of either rosacea or acne vulgaris comprising administering to a human patient in need thereof a modified release oral composition comprising:(i) about 30 to less than about 50 mg of doxycycline, based on the equivalent weight of doxycycline base, wherein the doxycycline is in an amount of about 15-20% w/w;(ii) about 10-18% w/w of one or more water soluble and insoluble polymers; and(iii) about 1-20% w/w of one or more pharmaceutically acceptable excipients; [{'sub': 0', '30, '(a) average input rate of about 4 ng/hr/mL to about 15 ng/hr/mL during a time period of Tmin to Tmin, and'}, {'sub': 0', '60, '(b) average input rate of about 15 ng/hr/mL to about 40 ng/hr/mL during a time period of Tmin to Tmin.'}], 'wherein the composition is free of any immediate release component; and wherein the composition provides at least one of the following pharmacokinetic parameters13. The method according to claim 12 , wherein the doxycycline is an acid addition salt of doxycycline.14. The method according to claim 13 , wherein the acid addition salt of doxycycline is doxycycline hyclate.15. The method according to claim 14 , wherein the doxycycline hyclate is present in an amount of about 46 mg.16. The method according to claim 12 , wherein the composition exhibits a reduced food effect selected from the group consisting of an AUC of less than about 15% and a Cof less than about 40% upon oral administration to a human.17. The method according to claim 16 , wherein the composition exhibits a reduced food effect as a Cof less than about 35 ...

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Номер записи: 66

18-01-2018 дата публикации

Multi-Compartment Capsule

Номер: US20180015044A1

Автор: Gazzaniga Andrea, Melocchi Alice, Parietti Federico, Zema Lucia

Принадлежит:

A method of making a capsule comprising a plurality of compartments, the method comprising: initiating extrusion of a filament solution through a filament extruder; laying the filament solution to form a base of the capsule; forming a first compartment in the plurality of compartments, wherein the forming creates a first barrier wall having a first predetermined release time; forming a second compartment in the plurality of compartments, wherein the forming creates a second barrier wall having a second predetermined release time; filling the first compartment with a first material; filling the second compartment with a second material; and sealing the plurality of compartments thereby forming the capsule with a first sealed compartment and a second sealed compartment. 1. A method of making a capsule comprising a plurality of compartments , the method comprising:A) initiating extrusion of a filament solution through a filament extruder;B) laying the filament solution to form a base of the capsule;C) forming a first compartment in the plurality of compartments, wherein the forming C) creates a first barrier wall having a first predetermined release time;D) forming a second compartment in the plurality of compartments, wherein the forming D) creates a second barrier wall having a second predetermined release time;E) filling the first compartment with a first material;F) filling the second compartment with a second material; andG) sealing the plurality of compartments thereby forming the capsule with a first sealed compartment and a second sealed compartment.2. The method of wherein the forming C) and forming D) and performed concurrently.3. The method of wherein the forming C) and forming D) and performed sequentially.4. The method of wherein the first predetermined release time is different than the second predetermined release time.5. The method of wherein the first predetermined release time is the same as the second predetermined release time.6. The method of ...

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Номер записи: 67

18-01-2018 дата публикации

COMPOSITION FOR ENTERIC HARD CAPSULE AND METHOD FOR PRODUCING ENTERIC HARD CAPSULE

Номер: US20180015045A1

Автор: Maruyama Naosuke

Принадлежит: SHIN-ETSU CHEMICAL CO., LTD.

A composition for an enteric hard capsule by taking advantage of conventionally unknown thermal gelation characteristics of a neutralized aqueous solution of an enteric polymer, so as to obtain an enteric capsule having sufficient water and acid resistances. More specifically, the composition has hypromellose acetate succinate having a molar substitution with an acetyl group per anhydroglucose unit of 0.6 to 0.8 and a ratio of the molar substitution with an acetyl group to a molar substitution with a succinyl group per anhydroglucose unit of 2.0 to 4.0, a neutralizer, and water method produces an enteric hard capsule having the steps of: immersing a core pin heated at 50 to 80° C. in the composition, taking the immersed core pin out of the composition, and drying a gel layer of the hypromellose acetate succinate formed on the taken-out core pin. 1. A composition for an enteric hard capsule , the composition comprising:hypromellose acetate succinate having a molar substitution with an acetyl group per anhydroglucose unit of 0.6 to 0.8 and a ratio of the molar substitution with an acetyl group to a molar substitution with a succinyl group per anhydroglucose unit of 2.0 to 4.0;a neutralizer; andwater.2. The composition for an enteric hard capsule according to claim 1 , wherein a 15% by weight aqueous solution of the hypromellose acetate succinate neutralized with ammonia in an amount equivalent to the molar substitution with a succinyl group has a gelation temperature of 5 to 60° C.3. The composition for an enteric hard capsule according to claim 1 , wherein a 15% by weight aqueous solution of the hypromellose acetate succinate neutralized with ammonia in an amount equivalent to the molar substitution with a succinyl group has a gel strength at 60° C. of 10 Pa or more.4. The composition for an enteric hard capsule according to claim 1 , wherein the neutralizer is contained in an amount of 80 to 120% by mole claim 1 , relative to the molar substitution with a succinyl ...

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Номер записи: 68

17-01-2019 дата публикации

Use of a Polyanionic Composition

Номер: US20190015514A1

Автор: DANGERFIELD John A., Gunzburg Walter H., Tan Wee Jin

Принадлежит:

Disclosed herein is a use of a composition, comprising a non-toxic polyanionic material or a salt thereof to dissociate a polymeric membrane. In addition, a method of dissociating a polymeric membrane is also presented, the method comprising the steps of providing a polymeric membrane; and dissociating the polymeric membrane by adding a composition comprising a non-toxic polyanionic material to the polymeric membrane. 1. Use of a composition comprising a non-toxic polyanionic material or a salt thereof to dissociate a polymeric membrane , wherein the non-toxic polyanionic material is a polysaccharide sulfate , a poly(sodium styrene sulfonate) or a polyacrylic acid or a salt thereof , provided that the polysaccharide sulfate is not a glycosoaminoglycan.2. The use of claim 1 , wherein the polymeric membrane is in the form of a capsule that encapsulates a substance or in the form of a barrier that blocks free movement of a substance.3. The use of or claim 1 , wherein the polymeric membrane comprises sodium cellulose sulfate and polydiallyldimethylammonium chloride (pDADMAC).4. The use of or claim 1 , wherein the substance is selected from one or more of the group consisting of cells claim 1 , proteins claim 1 , biocompatible particles claim 1 , and chemical compounds claim 1 , optionally wherein the substance is a plurality of cells.5. The use of any one of the preceding claims claim 1 , wherein the polyanionic material or a salt thereof has a number average molecular weight of from 4 claim 1 ,000 to 20 claim 1 ,000 Daltons claim 1 , optionally from 4 claim 1 ,500 to 15 claim 1 ,000 Daltons (e.g. from 5 claim 1 ,000 to 10 claim 1 ,000 Daltons claim 1 , such as 5 claim 1 ,000 Daltons).6. The use of any one of the preceding claims claim 1 , wherein the polyanionic material or salt thereof is a polysaccharide sulfate claim 1 , optionally wherein each saccharide unit of the polysaccharide sulfate contains from 1 to 3 sulfate groups.7. The use of claim 6 , wherein the ...

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Номер записи: 69

21-01-2016 дата публикации

Benzene Polycarboxylic Acid Compounds and Their Use as Drug

Номер: US20160017104A1

Автор: Fedoros Elena I., Pigarev Evgeny Sergeevich, Shipov Valery Pavlovich

Принадлежит: RDInnovation ApS

The present invention relates to new benzene polycarboxylic acids compound, which is prepared by alkaline oxidation of hydrolyzed lignin. The present invention also relates to the use of the new benzene polycarboxylic acids compound as part of a composite substance, where the composite substance is prepared by complexing or encapsulating the new benzene polycarboxylic acid compounds with a metal cation. The present invention also relates to a method for preparing the new benzene polycarboxylic acids compound and for its use in cosmetic, nutraceutical and pharmaceutical compositions.

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Номер записи: 70

18-01-2018 дата публикации

THERMOSET FOAMS, AND METHOD FOR MANUFACTURING SAME FROM REDUCING SUGARS AND AMINES

Номер: US20180016356A1

Автор: Savonnet Marie

Принадлежит: SAINT-GOBAIN ISOVER

A process for manufacturing a solid thermoset foam includes the following successive stages: (a) providing an expandable and thermosetting composition including a first reactant chosen from reducing sugars and a second reactant chosen from primary amines, primary amine acid addition salts, secondary amines, secondary amine acid addition salts, and ammonium salts of formula R(NH)where n is an integer at least equal to 1 and R represents the residue of an organic or inorganic acid; (b) introducing the expandable and thermosetting composition into a mold or applying the expandable composition to a support so as to form a film having a thickness at least equal to 1 mm; and (c) heating the expandable and thermosetting composition to a temperature at least equal to 140° C. to react the first reactant with the second reactant and to form, by polymerization and chemical foaming, a block of solid thermoset foam. 1. A process for manufacturing a solid thermoset foam , comprising the following successive stages: a first reactant chosen from reducing sugars,', {'sup': n−', '+', 'n−, 'sub': 4', 'n, 'a second reactant chosen from primary amines, primary amine acid addition salts, secondary amines, secondary amine acid addition salts, and ammonium salts of formula R(NH)where n is an integer at least equal to 1 and R represents a residue of an organic or inorganic acid,'}, 'the expandable and thermosetting composition containing less than 50% by weight of water,, '(a) making available an expandable and thermosetting composition containing(b) introducing the expandable and thermosetting composition into a mold or applying the expandable and thermosetting composition on a support so as to form a film having a thickness at least equal to 1 mm,(c) heating the expandable and thermosetting composition to a temperature at least equal to 140° C., so as to react the first reactant with the second reactant and to form, by polymerization and chemical foaming, a block of solid thermoset foam.2 ...

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Номер записи: 71

17-01-2019 дата публикации

Moldable compositions and methods of using thereof

Номер: US20190016877A1

Автор: Anthony C. Drago, III, David E. Rowan, Michael G. Moskal, Michael L. Spera

Принадлежит: Crayola LLC

The present invention provides moldable compositions that are capable of resisting slumping and cracking when allowed to dry and harden. Embodiments of the moldable composition comprise water, fillers including arrowroot and kaolin clay, at least one polar polymeric resin (e.g., polyvinyl alcohol), at least one thickening agent (e.g., ammonium pentaborate tetrahydrate), one or more pH adjusters (e.g., triethanolamine, sodium bicarbonate), a humectant (e.g., propylene glycol, glycerin), optionally at least one releasing agent (e.g., mineral oil), and optionally at least one additive.

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Номер записи: 72

22-01-2015 дата публикации

Gastric Reflux Resistant Dosage Forms

Номер: US20150024044A1

Автор: Chidambaram Nachiappan

Принадлежит:

Gastric resistant film-forming compositions are described herein. The composition comprises a gastric resistant natural polymer, a film-forming natural polymer, and optionally a gelling agent. Suitable gastric resistant natural polymers include polysaccharides such as pectin and pectin-like polymers. The film-forming composition can be used to prepare soft or hard shell gelatin capsules which can encapsulate a liquid or semi-solid fill material or a solid tablet (Softlet®) comprising an active agent and one or more pharmaceutically acceptable excipients. Alternatively, the composition can be administered as a liquid with an active agent dissolved or dispersed in the composition. The compositions are not only gastric resistant but may also prevent gastric reflux associated with odor causing liquids, such as fish oil or garlic oil, encapsulated in a unit dosage form and esophageal irritation due to the reflux of irritant drugs delivered orally. 134-. (canceled)35. An oral gastric resistant soft capsule shell , prepared by a process comprising:A) preparing a mixture comprising(a) pectin in an amount from 2% to less than 5% by weight;(b) gelatin in an amount from 25% to 40% by weight;(c) glycerol in an amount from 8% to 30% by weight;(d) a divalent cation in an amount from 1% to 2% by weight;(e) water;B) casting the gel mass into films or ribbons; andC) forming the capsule shell.36. The capsule shell of claim 35 , wherein the concentration of pectin is from 2% to 4% by weight.37. The capsule shell of claim 35 , wherein the divalent cation is selected from the group consisting of calcium salts claim 35 , magnesium salts claim 35 , and calcium gelatin.38. The capsule shell of claim 35 , wherein the mixture further comprises one or more excipients selected from the group consisting of opacifiers claim 35 , colorants claim 35 , humectants claim 35 , preservatives claim 35 , flavorings claim 35 , buffering salts and acids claim 35 , and combinations thereof.39. The capsule ...

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Номер записи: 73

17-04-2014 дата публикации

PROCESS FOR MANUFACTURING A SURFACE-TREATED COMPACTED MATERIAL PROCESSABLE ON A SINGLE SCREW PLASTICS CONVERSION EQUIPMENT

Номер: US20140107258A1

Автор: Ammann Ernst, Haldemann Peter, Hersche Emil, Knerr Michael

Принадлежит:

The present invention relates to the field of processing thermoplastic polymers, particularly the present invention relates to a process for manufacturing compacted material suitable for the use in thermoplastic polymers without a compounding step, comprising the steps of a) providing at least one primary powder material; b) providing at least one molten surface treatment polymer; c) simultaneously or subsequently feeding the at least one primary powder material and the at least one molten surface treatment polymer into the high speed mixer unit of a cylindrical treatment chamber; d) mixing the at least one primary powder material and the at least one molten surface treatment polymer in the high speed mixer, e) transferring the mixed material obtained from step d) to a cooling unit, as well as the compacted material obtained by this process and its use in thermoplastic polymers. 1. A surface-treated compacted material obtained by a process comprising the following steps:a) providing at least one primary powder material;b) providing at least one molten surface treatment polymer;c) simultaneously or subsequently feeding the at least one primary powder material and the at least one molten surface treatment polymer into the high speed mixer unit of a cylindrical treatment chamber;d) mixing the at least one primary powder material and the at least one molten surface treatment polymer in the high speed mixer; ande) transferring the mixed material obtained from step d) to a cooling unit.2. The surface-treated compacted material according to claim 1 , that is completely redispersible in thermoplastic polymer matrices without compounding step.3. The surface-treated compacted material according to claim 1 , that is non-dusting.4. The surface-treated compacted material according to claim 1 , wherein at least one surface treatment agent is fed simultaneously with or after the feeding of the at least one primary powder material into the high speed mixer unit of a cylindrical ...

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Номер записи: 74

25-01-2018 дата публикации

BINDER COMPOSITIONS AND PROCESSES OF PREPARING IRON ORE PELLETS

Номер: US20180023167A1

Автор: Luo Yuping, Macy Patrick, Moore Lucas

Принадлежит:

Binder compositions for agglomerating iron ore fines are provided, the compositions comprising: one or more types of modified starch and one or more types of synthetic dry polymers. A process for preparing iron ore pellets with the binder compositions is also provided, the process comprising: (i) adding a binder composition to particulate iron ore to form a mixture; and (ii) forming the mixture into pellets. 1. A binder composition for agglomerating iron ore fines comprising: one or more types of modified starch and one or more types of synthetic dry polymer.2. The composition of claim 1 , wherein the composition comprises:(a) about 5 to about 50% by weight one or more types of modified starch; and(b) about 50 to about 95% by weight one or more types of synthetic dry polymer.3. The composition of claim 1 , wherein the composition comprises: (a) about 20 to about 50% by weight one or more types of modified starch; and (b) about 50 to about 80% by weight one or more types of synthetic dry polymer.4. The composition of claim 1 , wherein the modified starch is gelled corn starch.5. The composition of claim 1 , wherein the binder composition further comprises one or more types of alkaline materials.6. The composition of claim 1 , wherein the synthetic dry polymer is anionic or has a net anionic charge.7. The composition of claim 1 , wherein the synthetic dry polymer is an acrylamide-containing polymer.8. The composition of claim 1 , wherein the synthetic dry polymer is a copolymer of acrylamide and acrylic acid.9. The composition of claim 1 , wherein the charge of the synthetic dry polymer is from about 5 to about 40 mole % charge.10. The composition of claim 1 , wherein the charge of the synthetic dry polymer is from about 5 to about 15 mole %.11. The composition of claim 1 , comprising at least 25% modified starch.12. The composition of claim 1 , comprising about 20 to about 50% gelled corn starch and about 50 to about 80% a copolymer of acrylamide and acrylic acid ...

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Номер записи: 75

10-02-2022 дата публикации

Method for producing low-cost fully biodegradable disposable straw

Номер: US20220041865A1

Автор: Dong Wu, Jingren HE, Rui Zhang, Shuxin YE, Sijia JIANG, Yubao Li

Принадлежит: China Yunhong Holdings Co Ltd, Guozhong Xinghe Biomedical Technology Co Ltd, Yunhong Environmental Technology Co Ltd

A method for producing a low-cost fully biodegradable disposable straw. Natural plant powder is prepared. Deacetylated konjac gel is prepared. The taro starch-cassava starch is crosslinked. The raw material is stirred and mixed to obtain the mixed raw material, and the mixed raw material is heated. The heated raw material is added to the beverage straw manufacturing unit to obtain a straw crude. The straw crude is cut to obtain several straws. The quality inspection, the disinfection and the packaging of the straw are carried out, and the fully biodegradable straw is obtained, finally.

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Номер записи: 76

23-01-2020 дата публикации

DEBRANCHING ENZYME MODIFIED STARCH, THE PREPARING METHOD AND USE THEREOF IN HARD CAPSULE PRODUCTION

Номер: US20200023064A1

Автор: CHANG Ruei-Jan, CHAO Hsin-Yi, Chen Wei-yu, Lee Pei-Hsuan

Принадлежит:

The present invention relates to a modified starch and a method for obtaining the modified starch by using a debranching enzyme, such as isoamylase, pullulanase, limit dextrinase and the like. The debranching enzyme modified starch of present invention exhibits excellent film-forming capacity, film strength, and gelation ability, so as to be used as a material for making hard capsules without the use of coagulants and plasticizers. 1. A modified starch gel composition for producing hard empty capsules , comprising a debranching enzyme modified starch solution , wherein the modified starch has a degree of branching that is reduced by 30% to 70% and posesses gelation ability and sufficient film strength for preparing hard empty capsules without additional plasticizer and coagulant.2. The modified starch gel composition according to claim 1 , wherein the starch solution is prepared from a starch which is selected from the group consisting of natural starch.3. The modified starch gel composition according to claim 1 , wherein the modified starch has a degree of branching that is reduced by 30% to 50%.4. The modified starch gel composition according to claim 1 , wherein the modified starch gel has a viscosity of 500 to 5 claim 1 ,000 cP measured at a gel temperature of 60° C.5. The modified starch gel composition according to claim 1 , wherein the debranching enzyme is a pullulanase.6. (canceled)7. (canceled)8. A method of preparing the modified starch gel according to claim 1 , which comprises:dissolving the starch in water (1:2-1:10 wt/wt) to obtain the starch solution;adding the debranching enzyme to the starch solution to obtain a mixture (the amount of the debranching enzyme is 0.00001% to 5% of the weight of the starch), and reacting at 40-70° C. for 0.5-5 hours;heating the mixture to 80° C. or above to inactivate the debranching enzyme; andcooling the mixture to 40-70° C. to obtain the modified starch gel.9. The method of preparing the modified starch gel ...

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Номер записи: 77

28-01-2021 дата публикации

SILICIC ACID FORMULATION AND USE THEREOF

Номер: US20210023125A1

Автор: CALOMME Mario Remi Yvonne, PASSWATER Richard Alan, VAN DE SOMPELE Patrick Wilfried Godfried

Принадлежит:

The capsule comprises a capsule shell and filled With an acidic liquid formulation comprising stabilized silicic acid, wherein the capsule shell comprises a polysaccharide and/or a polysaccharide derivative. The stabilization may be achieved with a quaternary ammonium compound. The capsule can be part of a capsule-in-capsule product, wherein the outer capsule contains furthermore a composition such as an oil. The capsule may be applied as a dietary supplement or as a medicament. 1. A capsule comprising a capsule shell and filled with an acidic liquid formulation comprising stabilized silicic acid , wherein the capsule shell comprises a polysaccharide and/or a polysaccharide derivative.2. The capsule of claim 1 , wherein the stabilized silicic acid substantially comprises monomers and/or oligomers of silicic acid.3. The capsule of claim 1 , wherein the liquid formulation has a pH in the range of 0 to 2.5.4. The capsule of claim 1 , wherein the silicic acid is stabilized with a quaternary ammonium compound claim 1 , such as a choline compound claim 1 , wherein the quaternary claim 1 , ammonium compound is present in a concentration of at least 20 wt % of the liquid formulation.5. The capsule of claim 1 , wherein the formulation comprises water in an amount of at most 15 wt % water.6. The capsule of claim 1 , wherein the formulation has a viscosity in the range of 0.08.10to 2.0.10mPas.7. The capsule of claim 6 , wherein the formulation further comprises a rheological additive chosen from the group of amorphous silica.8. The capsule of claim 7 , wherein the liquid formulation contains a diluent in an amount of at most 10 wt % or is free of diluents.9. The capsule of claim 1 , wherein the polysaccharide and/or polysaccharide derivative is chosen from the group of cellulose claim 1 , cellulose derivative claim 1 , starch claim 1 , modified starch claim 1 , pullulan and dextran and mixtures thereof.10. The capsule of claim 9 , wherein the cellulose and/or cellulose ...

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Номер записи: 78

23-01-2020 дата публикации

BIODEGRADABLE NATURAL PLASTIC CONTAINER

Номер: US20200024044A1

Автор: Wright Monica Elizabeth

Принадлежит:

A biodegradable container made from plant-based plastic that holds, in a preferred embodiment, one to two ounces of a gel-like or otherwise viscous liquid for immediate nutrition. Once opened and used, the container can be safely disposed of on the ground where it will be broken down by natural factors like rain over several days. 1. A container for a nutrition product comprising:a flexible container body formed at one end with an integral tear-away tab, the container body comprising naturally biodegradable bioplastic material.2. The container of wherein said biodegradable bioplastic material is edible and is made from a composition comprising water and/or juice; starch; acetic acid; citric acid; and plant-based glycerin.3. The container of wherein said biodegradable and edible plastic material is made from a composition comprising at least 73.2-77.4% water claim 1 , fruit juice claim 1 , vegetable juice or any combination thereof.4. The container of claim 3 , wherein the composition comprises 7.7-9.2% starch claim 3 , wherein the starch is selected from the group consisting of corn starch claim 3 , potato starch claim 3 , tapioca starch claim 3 , wheat starch claim 3 , rice starch claim 3 , and mixtures thereof.5. The container of claim 4 , wherein the composition comprises 3.0-4.6% acetic acid.6. The container of claim 5 , wherein the composition comprises 7.7-9.2% citric acid.7. The container of claim 6 , wherein the composition comprises 1.3-1.5% plant-based glycerin.8. The container of claim 7 , wherein the composition comprises 1.9-2.3% agarose and agaropectin mixture.9. The container of claim 8 , wherein the composition comprises 1.1% collagen.10. The container of claim 9 , wherein the composition comprises less than 0.1% thyme oil.11. A one-piece container for a nutrition product comprising a pair of flexible sheets joined about a peripheral edge portion and including an integral tear away tab portion claim 9 , said flexible sheets comprising a naturally ...

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Номер записи: 79

23-01-2020 дата публикации

HIGH TEMPERATURE TOLERANT, MODIFIED CATIONIC STARCH-BASED ADDITIVES FOR WATER CLARIFICATION

Номер: US20200024527A1

Автор: Jakubowski Wojciech, Thomas Jason J., Tomla Cristabel

Принадлежит: Baker Hughes, a GE company, LLC

The present disclosure is directed to additives comprising modified cationic starches that may be applied to a production fluid at high temperatures, such as temperatures ranging from about 80° C. to about 300° C., for separating water from an emulsion in the production fluid. 1. A method for separating water from an emulsion comprising hydrocarbons and water , the method comprising: introducing an additive into a fluid containing the emulsion , the additive comprising an effective amount of a modified cationic starch to separate at least a portion of the water from the emulsion , wherein the temperature of the fluid or the additive ranges from about 80° C. to about 300° C.2. The method of claim 1 , wherein the fluid is a production fluid selected from the group consisting of a hydrocarbon stream claim 1 , an aqueous stream claim 1 , and combinations thereof.3. The method of claim 1 , wherein the additive further comprises a water clarifier compound.4. The method of claim 3 , wherein the water clarifier compound is selected from a group consisting of polycondensate based on N claim 3 ,N′-bis[3-(dimethylamino)propyl]urea claim 3 , polyacrylate copolymers claim 3 , polyacrylamide copolymers claim 3 , poly(acrylate/acrylamide) copolymers claim 3 , polycondensate based on alkanolamines claim 3 , and combinations thereof.5. The method of claim 1 , wherein the modified cationic starch is derived from a starch selected from a group consisting of corn starches claim 1 , potato starches claim 1 , tapioca starches claim 1 , sago starches claim 1 , rice starches claim 1 , wheat starches claim 1 , waxy maize starches claim 1 , grain sorghum starches claim 1 , grain starches claim 1 , plant starches claim 1 , carbohydrates claim 1 , lignin claim 1 , polysaccharides claim 1 , and combinations thereof.6. The method of claim 1 , wherein the modified cationic starch is a quaternary ammonium cation starch. The method of claim 1 , wherein the additive comprises 36 wt. % to about 95 wt ...

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Номер записи: 80

04-02-2016 дата публикации

COHERENT BLOOD COAGULATION STRUCTURE OF WATER-INSOLUBLE CHITOSAN AND WATER-DISPERSIBLE STARCH COATING

Номер: US20160030623A1

Автор: Drake James F.

Принадлежит:

An absorbent layer for moderating blood flow from a wound has a non-woven fabric layer of water-insoluble chitosan fibers having a coating of water-absorbent starch on at least one face of the fabric layer. The coating of water-absorbent starch penetrates into the fabric layer from a first surface over the chitosan fibers to a depth of at least 25% of the fabric layer of chitosan fibers. The chitosan fibers have average diameters of from 5 to 30 micrometers. The average weight of starch/chitosan may decrease from the first surface from which the starch has penetrated into the fabric to the depth of at least 50% of the fabric layer. The starch may be modified to include hydrophilic groups into or onto molecular chains of the starch. 1. An absorbent layer comprising a non-woven fabric layer of water-insoluble chitosan fibers having a coating of water-absorbent starch on at least one face of the fabric layer.2. The layer of wherein the coating of water-absorbent starch penetrates into the fabric layer from a first surface over the chitosan fibers to a depth of at least 25% of the fabric layer of chitosan fibers.3. The layer of wherein the chitosan fibers have average diameters of from 5 to 30 micrometers.4. The layer of wherein the chitosan fibers have average diameters of from 8 to 25 micrometers.5. The layer of wherein the chitosan fibers have average diameters of from 10 to 20 micrometers.6. The layer of wherein the chitosan fibers have average diameters of from 8 to 25 micrometers.7. The layer of wherein the coating of water-absorbent starch penetrates from a first surface into the fabric layer over the chitosan fibers to a depth of at least 50% of the fabric layer of chitosan fibers towards a second surface of the layer.8. The layer of wherein the coating of water-absorbent starch penetrates from a first surface into the fabric layer over the chitosan fibers to a depth of at least 50% of the fabric layer of chitosan fibers towards a second surface of the layer.9. ...

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Номер записи: 81

02-02-2017 дата публикации

SUPRAMOLECULAR CAPSULES

Номер: US20170028374A1

Автор: Abell Christopher, COULSTON Roger, Scherman Oren Alexander, Zhang Jing

Принадлежит: Cambridge Enterprise Limited

Provided is a capsule having a shell of material that is a supramolecular cross-linked network. The network is formed from a host-guest complexation of cucurbituril (the host) and one or more building blocks comprising suitable guest functionality. The complex non-covalently crosslinks the building block and/or non-covalently links the building block to another building block thereby forming the supramolecular cross-linked network. The capsules are obtained or obtainable by the complexation of a composition comprising cucurbituril and one or more building blocks having suitable cucurbituril guest functionality thereby to form a supramolecular cross-linked network. 1. A capsule having a shell which is obtainable from the complexation of a composition comprising a host and one or more building blocks having suitable host guest functionality thereby to form a supramolecular cross-linked network.2. The capsule of claim 1 , wherein the host is selected from cucurbituril claim 1 , cyclodextrin claim 1 , calix[n]arene claim 1 , and crown ether claim 1 , and the one or more building blocks have suitable host guest functionality for the cucurbituril claim 1 , cyclodextrin claim 1 , calix[n]arene or crown ether host.3. The capsule of claim 2 , wherein the host is cucurbituril and the one or more building blocks have suitable cucurbituril guest functionality.4. The capsule of claim 3 , wherein the shell is obtainable from the complexation of (a) a composition comprising cucurbituril and (1) or (2); or (b) a composition comprising a plurality of covalently linked cucurbituril and (1) claim 3 , (2) or (3) claim 3 , wherein:(1) comprises a first building block covalently linked to a plurality of first cucurbituril guest molecules and a second building block covalently linked to a plurality of second cucurbituril guest molecules, wherein a first guest molecule and a second guest molecule together with cucurbituril are suitable for forming a ternary guest-host complex,(2) comprises ...

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Номер записи: 82

02-02-2017 дата публикации

Starch Compositions And Use Thereof

Номер: US20170029601A1

Автор: McCaffrey Nicholas John

Принадлежит:

There is provided a starch composition comprising a crosslinked starch. The composition may be useful in a variety of applications, for example, in thermoformed articles or as a component in multilayer films. 2. The starch composition according to claim 1 , wherein the at least one second starch is present in an amount of at least 5% by weight based on the total dry weight of starch in the composition.3. The starch composition according to claim 1 , wherein the at least one second starch is present in an amount from between 5% to 50% by weight claim 1 , based on the total dry weight of starch in the composition.4. The starch composition according to claim 1 , wherein the at least one second starch is derived from a non-crosslinked starch treated with from 0.001 to 5% by weight of one or more crosslinking agents based on the dry weight of the non-crosslinked starch.5. The starch composition according to claim 4 , wherein the crosslinking agent is selected from phosphorus oxychloride claim 4 , epichlorohydrin claim 4 , hydrophobic cationic epoxides claim 4 , sulphates claim 4 , diacid anhydrides and phosphate derivatives prepared by reaction with sodium or potassium orthophosphate or tripolyphosphate and combinations thereof.6. The starch composition according to claim 1 , wherein the chemical modification independently comprises a hydroxyalkyl Cgroup or the product of reaction of starch with an anhydride of a carboxylic acid.7. The starch composition according to claim 1 , wherein the first and second starch are chemically modified so as to have a degree of substitution independently from 0.01 to 1.5.8. The starch composition according to claim 1 , wherein the first or second starch is independently selected from wheat starch claim 1 , corn starch claim 1 , tapioca starch claim 1 , potato starch claim 1 , cassava starch claim 1 , pea starch claim 1 , oat starch claim 1 , arrowroot starch or rice starch or mixtures thereof.9. The starch composition according to claim ...

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Номер записи: 83

17-02-2022 дата публикации

Drug composition for treating breast cancer and method for manufacturing the same

Номер: US20220047559A1

Автор: Chu-Ting Li, Dean-Mo Liu, Wen-Lien Wang

Принадлежит: National Chiao Tung University Hsinchu City Taiwan

The present invention relates to a drug composition and method for treating breast cancer, and more specifically, to use carboxymethyl-hexanoyl chitosan (CHC) to co-encapsulate a heat shock protein 90 (HSP90) inhibitor and a hydrophobic drug. The two drugs can be co-encapsulated with high encapsulation efficiency and co-delivered to breast cancerous cells, and achieve a synergistic efficacy to kill the cancerous cells.

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Номер записи: 84

31-01-2019 дата публикации

METHODS AND SYSTEMS FOR IMPROVED BIOAVAILABILITY OF ACTIVE PHARMACEUTICAL INGREDIENTS INCLUDING ESOMEPRAZOLE

Номер: US20190029965A1

Автор: Benameur Hassan, Lee Chang Q.

Принадлежит: Capsugel Belgium NV

The present disclosure relates to delivery systems and methods for increasing the bioavailability and increasing the absorption rate by monolithic enteric capsule administration to humans of active ingredients compared to the bioavailability of active ingredients enterically coated for modified release or gastric protection, particularly acid sensitive active ingredients such as esomeprazole, omeprazole, and other proton pump inhibitors, systems for delivering active pharmaceutical ingredients to humans or animals via monolithic enteric capsules, and improved methods of treating gastrointestinal disorders with such methods and delivery systems. 1. An enteric drug delivery system comprising: a monolithic enteric hard capsule filled with the active pharmaceutical ingredient , wherein the active pharmaceutical ingredient has not been enterically coated for modified release or gastric protection , wherein less than about 10% of the active pharmaceutical ingredient is released from the monolithic enteric capsule after about 2 hours in a pH of about 1.2 , wherein at least about 80% of the active pharmaceutical ingredient is released from the monolithic enteric capsule after about 30 min at pH of about 6.8 , and wherein more than about 95% of the active ingredient is released in the intestine; wherein the active pharmaceutical ingredient is a proton pump inhibitor selected from the group consisting of dexlanzoprazole , esomeprazole , ilaprazole , leminoprazole , lanzoprazole , omeprazole , pantoprazole , paripiprazole , rabeprazole , tenatoprazole and combinations , pharmaceutically acceptable salts , derivatives , and enantiomers thereof.2. The system according to claim 1 , wherein the monolithic enteric capsule yields a peak plasma concentration (C) that is equal to or higher than the peak plasma concentration achieved by the active pharmaceutical ingredient from administration of an oral dosage form comprising at least one enteric coating for modified release or gastric ...

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Номер записи: 85

04-02-2021 дата публикации

GASTROINTESTINAL SITE-SPECIFIC ORAL VACCINATION FORMULATIONS ACTIVE ON THE ILEUM AND APPENDIX

Номер: US20210030669A1

Автор: KABADI Mohan, Schentag Jerome J.

Принадлежит:

The invention provides oral vaccine formulations which deliver an antigen in the vicinity of the distal ileum and the area of the ileal Brake and/or the appendix. These vaccines are useful in the treatment and/or prevention of variety of disorders, including viral and bacterial infections and cancers. Related methods of treatment which use the oral vaccine formulations of the invention are also provided. 1. An oral vaccine formulation which delivers an antigen in the vicinity of the distal ileum of the gastrointestinal tract and optionally , the appendix , the formulation comprising:(a) a plurality of cores, each of which comprise:(1) an antigen and an optional adjuvant;(2) a first enteric coating which encapsulates the antigen, which is substantially insoluble at a pH of less than a range of between about 7.0 to about 7.6, and which is comprised of one or more compositions selected from the group consisting of poly(dl-lactide-coglycolide, chitosan (Chi) stabilized with PVA (poly-vinylic alcohol), a lipid, an alginate, carboxymethylethylcellulose (CMEC), cellulose acetate trimellitiate (CAT), hydroxypropylmethyl cellulose phthalate (HPMCP), hydroxypropylmethyl cellulose, ethyl cellulose, color con, food glaze and mixtures of hydroxypropylmethyl cellulose and ethyl cellulose, polyvinyl acetate phthalate (PVAP), cellulose acetate phthalate (CAP), shellac, copolymers of methacrylic acid and ethyl acrylate, and copolymers of methacrylic acid and ethyl acrylate to which a monomer of methylacrylate has been added during polymerization; and optionally(3) a second enteric coating which is compositionally the same or different as the first coating, which is substantially insoluble at a pH of less than a range of between about 1.0 to about 5.3, which is encapsulated within the first coating, and which is comprised of one or more compositions selected from the group consisting of polyvinyl acetate phthalate (PVAP), cellulose acetate phthalate (CAP), shellac, copolymers of ...

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Номер записи: 86

11-02-2016 дата публикации

Non-Gelatin Enteric Soft Capsules

Номер: US20160038425A1

Автор: Fang Qi, Hariharan Madhu, HEFLIN Josh

Принадлежит:

Described herein are pharmaceutical enteric soft capsules that do not contain gelatin as a film-forming polymer. In particular, compositions and methods for manufacturing enteric soft capsules comprising carrageenans as film forming polymers are disclosed. 1. An oral enteric soft capsule shell formed from a gel mass composition comprising:(a) a carrageenan composition;(b) a filler;(c) a methacrylic acid copolymer;(d) one or more plasticizers;(e) an alkaline aqueous solvent; and(f) water.2. The composition of claim 1 , wherein the carrageenan composition comprises about 1% to about 15% of the gel mass.3. The composition of claim 1 , wherein the carrageenan composition comprises about 3% to about 5% of the gel mass.4. The composition of or claim 1 , wherein the carrageenan composition comprises iota carrageenan and kappa carrageenan.5. The composition of claim 4 , wherein the weight percentage ratio range of iota carrageenan to kappa carrageenan in the gel mass is about 2.5:1 to about 5:1.6. The composition of claim 4 , wherein the weight percentage ratio range of iota carrageenan to kappa carrageenan in the gel mass is about 3:1 to about 4:1.7. The composition of claim 4 , wherein the iota carrageenan comprises from about 0.5% to about 12% by weight of the gel mass.8. The composition of claim 4 , wherein the iota carrageenan is present in an amount of from about 9% to about 12% by weight of the gel mass.9. The composition of claim 4 , wherein the iota carrageenan comprises from about 2.5% to about 4% by weight of the gel mass.10. The composition of claim 4 , wherein the kappa carrageenan comprises from about 0.5% to about 4% by weight of the gel mass.11. The composition of claim 4 , wherein the kappa carrageenan comprises from about 0.5% to about 1% by weight of the gel mass.12. The composition of claim 1 , wherein the methacrylic acid copolymer comprises about 8% to about 20% of the gel mass.13. The composition of claim 1 , wherein the methacrylic acid copolymer ...

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Номер записи: 87

11-02-2016 дата публикации

LACTOBACILLUS PLANTARUM CAPSULE FOR POULTRY AND USE THEREOF

Номер: US20160038547A1

Автор: Li Jianshu, SHAO Suying

Принадлежит:

The present invention relates to a capsule and use thereof, and belongs to the technical field of microbe feed additives. The capsule consists of a wall material, , a cryoprotectant, stachyose, and zymolytic powders; wherein the wall material is composed of zymolytic soybean protein isolate, chitosan, xanthan gum, carrageenin, glycerin and trehalose, and when formulated into a mixed solution, the above substances have concentrations of 7 to 10% zymolytic soybean protein isolate, 1 to 2% chitosan, 1 to 3% xanthan gum, 0.1 to 0.5% carrageenin, 0.3 to 1% glycerin, and 0.5 to 2% trehalose. The capsule of the present invention enhances resistance of the capsule to gastric acid, has very good enteric solubility, besides, it can effectively inhibit the growth of pathogenic germs to improve immunity, decrease incidence of diseases in livestock and poultry, and improve the breeding quality and benefit. 1Lactobacillus plantarumLactobacillus plantarumMorchella esculentaLactobacillus plantarum. A capsule , consisting of a wall material , , a cryoprotectant , stachyose , and zymolytic powders , wherein the wall material is composed of zymolytic soybean protein isolate , chitosan , xanthan gum , carrageenin , glycerin and trehalose , and when formulated into a mixed solution , the above substances have concentrations of 7 to 10% zymolytic soybean protein isolate , 1 to 2% chitosan , 1 to 3% xanthan gum , 0.1 to 0.5% carrageenin , 0.3 to 1% glycerin , and 0.5 to 2% trehalose , respectively; the has a preservation number of CGMCC NO. 9405; and the cryoprotectant is composed of skim milk powder , trehalose , and maltodextrin.2Lactobacillus plantarum. The capsule of claim 1 , characterized in that claim 1 , the zymolytic soybean protein isolate is prepared by a method including: formulating a solution of soybean protein isolate at a concentration of 10 to 13% claim 1 , heating to 30-45° C. claim 1 , adjusting the solution to pH 3-5 claim 1 , added therein an acid proteinase at 0.1 to ...

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Номер записи: 88

09-02-2017 дата публикации

ACID RESISTANT BANDING SOLUTION FOR ACID RESISTANT TWO PIECE HARD CAPSULES

Номер: US20170035699A1

Автор: Cade Dominique Nicolas, He Xiongwei

Принадлежит: Capsugel Belgium NV

The present disclosure relates to acid resistant banding solutions for two piece hard capsules endowed with acid resistant properties, and methods of making and using acid resistant banding solutions. The present disclosure also relates, in part, to methods for banding such acid resistant capsules which provides an acid resistant seal between the capsule parts and achieves increased acid resistance in vitro. 1. A banded capsule dosage form comprising:a) an acid resistant, two piece hard capsule comprising a body and a cap;b) the body and the cap being telescopically engaged to encapsulate an active agent; andc) an acid resistant band around the two piece hard capsule that seals a gap between the body and the cap, the acid resistant band comprising at least one acid resistant polymer selected from hydroxypropyl methylcellulose phthalate (HPMCP), cellulose acetate phthalate (CAP), hydroxypropyl methylcellulose acetate succinate (HPMCAS), and mixtures thereof;wherein the banded capsule dosage form provides improved resistance to acid media relative to a non-banded, closed capsule dosage form, as evaluated using a United States Pharmacopeia (“USP”) disintegration method (Chapter 701) in pH 1.2 media.2. The banded capsule dosage form of wherein the two piece hard capsule comprises HPMC claim 1 , HPCMAS claim 1 , or CAP.3. The banded capsule dosage form according to claim 1 , wherein the acid resistant band was formed from a composition comprising at least one alkaline compound selected from sodium bicarbonate claim 1 , sodium carbonate claim 1 , potassium carbonate claim 1 , potassium bicarbonate claim 1 , sodium hydroxide claim 1 , tri sodium phosphate claim 1 , sodium perborate claim 1 , potassium hydroxide claim 1 , lithium hydroxide claim 1 , lithium carbonate claim 1 , lithium bicarbonate claim 1 , ammonium carbonate claim 1 , ammonium bicarbonate claim 1 , ammonium hydroxide claim 1 , ammonia claim 1 , and mixtures thereof.4. The banded capsule dosage form ...

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Номер записи: 89

24-02-2022 дата публикации

PHARMACEUTICAL FORMULATIONS OF A HIF HYDROXYLASE INHIBITOR

Номер: US20220054474A1

Автор: Conca David, Flippin Lee Allen, Leigh Scott David, Witschi Claudia, Wright Lee Robert

Принадлежит:

The present disclosure relates to pharmaceutical formulations of [(4-hydroxy-1-methyl-7-phenoxy-isoquinoline-3-carbonyl)-amino]-acetic acid and methods of use thereof. 1. A pharmaceutical composition formulated to prevent or reduce the photodegradation of an active ingredient [(4-hydroxy-1-methyl-7-phenoxy-isoquinoline-3-carbonyl)-amino]-acetic acid , the composition comprising the active ingredient [(4-hydroxy-1-methyl-7-phenoxy-isoquinoline-3-carbonyl)-amino]-acetic acid , and an effective amount of a photostabilizing agent , which photostabilizing agent:i) prevents the transmission of light at a wavelength range of between about 200 nm and 550 nm; andii) is admixed with the active ingredient, or provided in an outer coating or shell surrounding the active ingredient, such that the composition upon exposure to light contains less than about 0.2% w/w photodegradation product of [(4-hydroxy-1-methyl-7-phenoxy-isoquinoline-3-carbonyl)-amino]-acetic acid relative to the amount of [(4-hydroxy-1-methyl-7-phenoxy-isoquinoline-3-carbonyl)-amino]-acetic acid.2. The pharmaceutical composition of claim 1 , wherein the photostabilizing agent comprises titanium dioxide and at least one additional dye selected from the group consisting of a red dye claim 1 , a yellow dye claim 1 , and a combination of a red dye and a yellow dye.3. The pharmaceutical composition of claim 1 , wherein the photostabilizing agent comprises titanium dioxide and at least one additional dye selected from the group consisting of iron oxide red claim 1 , Allura Red AC claim 1 , Allura Red AC Aluminum Lake claim 1 , iron oxide yellow claim 1 , Sunset Yellow FCF claim 1 , and Sunset Yellow FCF Aluminum Lake claim 1 , or a combination thereof.4. The pharmaceutical composition of claim 1 , comprising from about 20 mg to about 200 mg of [(4-hydroxy-1-methyl-7-phenoxy-isoquinoline-3-carbonyl)-amino]-acetic acid.5. The pharmaceutical composition of claim 1 , comprising about 20 mg claim 1 , about 50 mg claim 1 ...

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Номер записи: 90

07-02-2019 дата публикации

Aqueous polymer dispersion, its use and method for preparing aqueous polymer dispersion

Номер: US20190040169A1

Автор: Lepo Anneli, Peuranen Helena

Принадлежит: KEMIRA OYJ

The invention relates to an aqueous polymer dispersion having a viscosity of ≤150 m Pas at 40% solids content and comprising polymer particles having a particle size D50 less than 85 nm. The polymer dispersion is obtainable by free radical emulsion copolymerisation of at least monomer (a) and monomer (b), where monomer (a) is at least one optionally substituted styrene and monomer (b) is at least one C1-C4-alkyl (meth)acrylate, in a reaction mixture comprising degraded starch which has an average molecular weight Mn<1000 g/mol. The invention relates also to the use of the polymer dispersion and method for preparing it. 2. The polymer dispersion according to claim 1 , wherein the aqueous polymer dispersion has the viscosity in the range of 1-150 mPas claim 1 , preferably 5-100 mPas claim 1 , more preferably 5-70 mPas claim 1 , even more preferably 5-49 mPas claim 1 , measured at 40 weight-% solids content.3. The polymer dispersion according to claim 1 , wherein the degraded starch has an average molecular weight Mn<800 g/mol claim 1 , preferably <500 g/mol.4. The polymer dispersion according to claim 1 , wherein the degraded starch may has an average molecular weight Mn in the range of 100-990 g/mol claim 1 , preferably 100-790 g/mol claim 1 , more preferably 100-490 g/mol claim 1 , even more preferably 100-400 g/mol.5. The polymer dispersion according to claim 1 , wherein the degraded starch is non-ionic or has an anionic net charge.6. The polymer dispersion according claim 1 , wherein the degraded starch is degraded anionic potato or tapioca starch.7. The polymer dispersion according claim 1 , wherein the amount of degraded starch in the reaction mixture at the beginning of the polymerisation is in the range of 5-60 weight-% claim 1 , preferably 10-45 weight-% claim 1 , more preferably 11-35 weight-%.8. The polymer dispersion according claim 1 , wherein the reaction mixture comprises also at least one monomer (c) claim 1 , which is ethylenically unsaturated and ...

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Номер записи: 91

18-02-2021 дата публикации

ENTERIC SOFTGEL CAPULES

Номер: US20210046013A1

Автор: Ahmad Humera, Do Jonathan, LIN JING

Принадлежит:

Enteric softgel capsules comprise a fill material and an enteric shell composition, characterized in that the enteric nature of the capsules may be achieved without an enteric coating or added conventional enteric polymers. 1. An enteric softgel capsule comprising:(a) a fill material; and wherein the fill material comprises at least one pharmaceutically active ingredient,', 'wherein the enteric shell composition comprises about 2% w/w to about 10% w/w of a carrageenan, about 10% w/w to about 30% w/w of a gelatin, about 10% w/w to about 35% w/w of a plasticizer, and about 20% w/w to about 50% why of a solvent, and', 'wherein the enteric softgel capsule is free of conventional enteric polymers., '(b) an enteric shell composition,'}2. An enteric softgel capsule comprising:(a) a fill material; and wherein the fill material comprises at least one pharmaceutically active ingredient,', 'wherein the enteric shell composition comprises about 2% w/w to about 10% w/w of a carrageenan, about 10% w/w to about 30% w/w of a gelatin, about 10% w/w to about 35% w/w of a plasticizer, about 20% w/w to about 50% w/w of a solvent, and about 0.1% w/w to about 3% w/w of a buffer and/or alkalizing agent, and', 'wherein the n ric softgel capsule is free of conventional enteric polymers., '(b) an enteric shell composition,'}3. The enteric softgel capsule of or , wherein the carrageenan comprises at least one of iota-carrageenan , kappa-carrageenan and mixtures thereof.4. The enteric saftgel capsule of claim 3 , wherein the carrageenan is iota-carrageenan.5. The enteric softgel capsule of or claim 3 , wherein the gelatin comprises at least one of Type A gelatin claim 3 , Type B gelatin and mixtures thereof.6. The enteric softgel capsule of or claim 3 , wherein the gelatin comprises at least one of fish gelatin claim 3 , hide gelatin claim 3 , bone gelatin and mixtures thereof.7. The enteric softgel capsule of claim 5 , wherein the gelatin is Type B high bloom gelatin.8. The enteric softgel ...

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Номер записи: 92

12-02-2015 дата публикации

METHODS AND COMPOSITIONS RELATING TO STARCH FIBERS

Номер: US20150045454A1

Автор: Kong Lingyan, Ziegler Gregory R.

Принадлежит: THE PENN STATE RESEARCH FOUNDATION

Methods are provided according to aspects of the present invention for making starch fiber or particle compositions by wet-electrospinning or wet-electrospraying including providing a solution or dispersion of starch in an aqueous or non-aqueous solvent or dispersant, where the starch is present at a concentration above the critical entanglement concentration, with the proviso that the aqueous or non-aqueous solvent or dispersant does not consist only of water; heating the solution or dispersion of starch to a temperature above the crystallization temperature of the starch; electro spinning or electro spraying the heated solution or dispersion of starch to produce starch fibers or starch particles, respectively; and contacting the starch fibers or starch particles with a coagulation bath fluid. 1. A method for making a starch fiber composition or starch particle composition , comprising:providing a spinning dope comprising a solution or dispersion of starch in an aqueous or non-aqueous solvent or dispersant, where the starch is present at a concentration above the critical entanglement concentration where starch fibers are to be produced or where the starch is present at a concentration from 1% to 40% weight % where starch particles are to be produced, with the proviso that the aqueous or non-aqueous solvent or dispersant does not consist only of water;heating the spinning dope to a temperature above the melting temperature or dissolution temperature of starch in the solvent or dispersant to produce a heated spinning dope;wet-electrospinning or wet-electrospraying the heated spinning dope to produce starch fibers or starch particles, respectively; andcontacting the starch fibers or starch particles with a coagulation bath fluid, forming a starch fiber composition or starch particle composition.2. The method of claim 1 , further comprising: washing the starch fiber composition or starch particle composition in a wash fluid to at least partially remove the solvent or ...

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Номер записи: 93

18-02-2021 дата публикации

INDUCTION HEATING SYSTEMS

Номер: US20210046297A1

Автор: FRYSHMAN Bernard

Принадлежит:

A food packaging system has a housing that includes a food receptacle. The food receptacle includes a food product that is available for purchase. A slot formed in the housing, and an induction heating element is positioned in the slot. 1. A food packaging system comprising:a housing that includes a food receptacle, wherein the food receptacle includes a food product that is available for purchase;a slot formed in the housing; andan induction heating element positioned in the slot.2. The food packaging system of claim 1 , wherein the housing is formed from a non-ferromagnetic material.3. The food packaging system of claim 1 , wherein the housing is formed from a heat resistant material.4. The food packaging system of claim 1 , wherein the housing includes a plurality of slots claim 1 , and further comprising a plurality of induction heating elements positioned in the plurality of slots.5. The food packaging system of claim 1 , wherein the induction heating element is positioned in the slot such that only a portion of the food product is heated by the induction heating element.6. The food packaging system of claim 1 , wherein the induction heating element includes a ferrous portion and a non-ferrous portion connected to the non-ferrous portion.7. The food packaging system of claim 6 , wherein the non-ferrous portion comprises a handle.8. The food packaging system of claim 1 , wherein the non-ferrous portion is made from a ceramic material.9. The food packaging system of claim 1 , wherein the food product comprises a dehydrated food claim 1 , and wherein the food receptacle is configured to receive water for preparation of the dehydrated food.10. The food packaging system of claim 1 , wherein claim 1 , upon receipt of electromagnetic radiation claim 1 , the induction heating element generates heat that warms the food product.11. A method of packaging food comprising:forming a housing that includes a food receptacle and a slot formed in the housing;placing a food ...

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Номер записи: 94

18-02-2016 дата публикации

PHARMACEUTICAL FORMULATION

Номер: US20160045436A1

Автор: Mohr Detlef, SOMMER Florian

Принадлежит:

The present invention relates to pharmaceutical formulations of highly active drugs with limited shelf-life in aqueous media, suitable to be administered by a caregiver person to a patient avoiding or minimizing the risk of exposure, contact or contamination of the caregiver person with the active product ingredient (API), preferably an EGFR-TKI such as afatinib dimaleate. 1. A pharmaceutical kit comprising(i) at least one water-soluble pharmaceutical capsule containing a powder formulation of a drug comprising an active pharmaceutical ingredient (API) susceptible to hydrolytic decomposition,(ii) 50 to 250 ml of a suitable pharmaceutically acceptable solvent as a reconstitution medium contained in a pharmaceutically acceptable container 5 to 300% oversized by volume, for preparation of an oral solution comprising the API ready for administration with a shelf-life of the oral solution of up to 6 months at ambient temperature, and, optionally(iii) an oral syringe of suitable volume and graduation which can be connected with the bottle via an adapter plug, for dosing and administration,and, optionally,(iv) handling instructions comprising preparation of the oral API solution, measurement, withdrawal and administration of a dose.2. The pharmaceutical kit of comprising(i) at least one water-soluble pharmaceutical capsule with capsule shells made of HPMC, PVA (polyvinylalcohol), starch or Pullulan (α-1,4-; α-1,6-glucan) containing a powder formulation comprising an API susceptible to hydrolytic decomposition, (a) 0.1%-5% by weight of one or more pharmaceutically acceptable artificial sweeteners or 0.1%-70% by weight of one or more pharmaceutically acceptable natural sweeteners or 0.1%-65% by weight of one or more pharmaceutically acceptable natural sweeteners and 0.1%-5% by weight of one or more pharmaceutically acceptable artificial sweeteners,', '(b) 0.01-1% by weight of one or more pharmaceutically acceptable acids,', '(c) 0.01-1% by weight of one or more ...

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Номер записи: 95

06-02-2020 дата публикации

ESTERIFIED STARCH AND STARCH-CONTAINING PLASTIC COMPOSITION

Номер: US20200040109A1

Автор: ITOH Kengou

Принадлежит: JAPAN CORN STARCH CO., LTD.

There is provided esterified starch which can be produced without using a non-aqueous organic solvent and has water resistance and miscibility with another plastic, and a starch-containing plastic composition. The esterified starch is obtained such that a starch mixture containing starch and a polyhydric alcohol, which is subjected to a heat treatment, is esterified with a vinyl ester and carbonate. Since the starch in the starch mixture enters a state in which starch granules are disintegrated by the polyhydric alcohol, by heating the starch mixture containing starch and a polyhydric alcohol, it is possible to esterify the starch without using a non-aqueous organic solvent and to obtain esterified starch having a high ester substitution degree. According to the esterified starch of the present invention, it is possible to obtain a starch-containing plastic composition having high hydrophobicity, and excellent water resistance and miscibility with another plastic. 1. An esterified starch obtained by performing an esterification treatment on a starch mixture containing starch and a polyhydric alcohol , which is subjected to a heat treatment , with a vinyl ester and carbonate.2. The esterified starch according to claim 1 , wherein no organic solvent is substantially used in the esterification treatment.3. The esterified starch according to claim 1 , wherein the starch mixture contains a dibasic acid.4. The esterified starch according to claim 1 , wherein the carbonate contains sodium carbonate.5. The esterified starch according to claim 1 , wherein the heat treatment is performed while the starch mixture is kneaded using a twin-screw extruder.6. The esterified starch according to claim 1 , wherein an ester substitution degree of the esterified starch is 1.0 to 2.9.7. A starch-containing plastic composition comprising:{'claim-ref': {'@idref': 'CLM-00001', 'claim 1'}, 'the esterified starch according to ; and'}plastic.8. The starch-containing plastic composition ...

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Номер записи: 96

16-02-2017 дата публикации

NON-STICKY NANOFIBROUS MEMBRANE HAVING CORE AND SHELL AND PROCESS OF PRODUCING SAME

Номер: US20170042822A1

Автор: Chen Chien-Tzung, Chen Chih-Hao, Chen Jyh-Ping, Chen Shih-Hsien, Shyu Victor Bong-Hang

Принадлежит:

A process of producing a non-sticky nanofibrous membrane includes pouring dimethylformamide (DMF) and dichloromethane into a first flask; pouring about 1 to about 40 wt % of polycaprolactone (PCL) into the first flask to prepare a PCL solution therein; keeping the first flask in a predetermined temperature wherein volumetric ratio of DMF and dichloromethane is 1:9 to 9:1; pouring hyaluronic acid (HA) into a second flask to prepare an HA solution having 1.75 wt % of HA; and activating an electrospinning technique to process the PCL solution in the first flask and the HA solution in the second flask, thereby producing an NFM having a core and a shell. 1. A process of producing a nanofibrous membrane (NFM) having a core and a shell comprising the steps of:(a) pouring dimethylformamide (DMF) and dichloromethane into a first flask;(b) pouring about 1 to about 40 wt % of polycaprolactone (PCL) into the first flask to prepare a PCL solution therein;(c) keeping the first flask in a predetermined temperature wherein volumetric ratio of DMF and dichloromethane is 1:9 to 9:1;(d) pouring hyaluronic acid (HA) into a second flask to prepare an HA solution having 1.75 wt % of HA; and(e) activating an electrospinning technique to process the PCL solution in the first flask and the HA solution in the second flask, thereby producing an NFM having a core and a shell.2. The process of claim 1 , wherein step (b) comprises the sub-steps of:(b-1) adding about 0.01 to about 10 wt % of silver nitrate to the first flask; and(b-2) placing the first flask in an ultraviolet box to be radiated for 3 hours to form nano silver by subjecting to optical reduction.3. The process of claim 2 , wherein volumetric ratio of DMF and dichloromethane is 2:8; 0.8 g of PCL is added to the first flask claim 2 , and the PCL solution has 8 wt % of PCL and 0.5 wt % of silver nitrate.4. The process of claim 1 , wherein the PCL is about 1.75 wt % and step (d) comprises the sub-steps of:(d-1) pouring about 0.5 wt % ...

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Номер записи: 97

16-02-2017 дата публикации

PENTAAZA MACROCYCLIC RING COMPLEXES POSSESSING ORAL BIOAVAILABILITY

Номер: US20170042907A1

Автор: KEENE Jeffery L., RILEY Dennis P., SCHALL Otto F.

Принадлежит:

Aspects of the present disclosure relate to compounds which have enhanced oral bioavailability. A transition metal complex includes a transition metal coordinated by a macrocycle comprising the pentaaza 15-membered macrocyclic ring corresponding to Formula A and two axial ligands having the formula —OC(O)X. 138-. (canceled)40. A pharmaceutical composition comprising the pentaaza macrocyclic ring complex of and a pharmaceutically acceptable excipient.41. The pharmaceutical composition of wherein the composition comprises linoleoyl polyoxyl-6 glycerides (NF).42. The pharmaceutical composition of wherein the pharmaceutical composition is suitable for oral administration to a human subject.43. The pharmaceutical composition of wherein the pharmaceutical composition is in a solid or semi-solid dosage form.44. The pharmaceutical composition of wherein the pharmaceutical composition is in the form of a tablets claim 40 , gelatin capsules claim 40 , HPMC capsules claim 40 , gel or suspension suitable for oral administration.45. The pharmaceutical composition of wherein the pharmaceutical composition comprises an enteric coating layer. The present disclosure generally relates to transition metal pentaaza 15-membered macrocyclic ring complexes which have improved properties, including significant oral bioavailability.Transition metal pentaaza 15-membered macrocyclic ring complexes having the macrocyclic ring system corresponding to Formula A have been shown to be effective in a number of animal and cell models of human disease, as well as in treatment of conditions afflicting human patients.For example, in a rodent model of colitis, one such compound, GC4403, has been reported when administered by intraperitoneal (ip) injection to significantly reduce the injury to the colon of rats subjected to an experimental model of colitis (see Cuzzocrea et al., 432, 79-89 (2001)).GC4403 administered ip has also been reported to attenuate the radiation damage arising both in a clinically ...

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Номер записи: 98

19-02-2015 дата публикации

ACID RESISTANT CAPSULES

Номер: US20150050334A1

Автор: Cade Dominique Nicolas, He Xiongwei David

Принадлежит:

The present invention relates to new acid resistant hard pharmaceutical capsules, a process for their manufacture and use of such capsules particularly but not exclusively for oral administration of pharmaceuticals, veterinary products, food and dietary supplements to humans or animals. The capsules of the invention are obtained by aqueous compositions comprising a water soluble film forming polymer and gellan gum in a mutual weight ratio of 4 to 15 weight parts of gellan gum for 100 weight parts of film forming polymer. 115-. (canceled)16. An aqueous composition comprising an aqueous solvent , gellan gum , and at least one water-soluble , film forming polymer , wherein the weight ratio of gellan gum to said at least one water soluble , film forming polymer is ranges from about 4/100 to about 15/100 , and wherein the composition does not comprise additional gelling aids.17. The aqueous composition according to claim 16 , further comprising at least one additive selected from the group consisting of inert claim 16 , non-toxic pharmaceutical grade or food grade pigments claim 16 , plasticizers claim 16 , surfactants claim 16 , and flavouring agents.18. The aqueous composition according to claim 16 , wherein the at least one water soluble film forming polymer is selected from the group consisting of HPMC claim 16 , gelatine claim 16 , pullulan claim 16 , PVA hydroxypropyl starch claim 16 , and mixtures thereof.19. The aqueous composition according to claim 18 , wherein the at least one water-soluble film forming polymer is selected from the group consisting of HPMC claim 18 , gelatin and mixtures thereof.20. The aqueous composition according to claim 19 , wherein the at least one water-soluble film forming polymer is HPMC.21. The aqueous composition according to claim 16 , wherein the ratio of gellan gum ranges from about 4.5/100 to about 6/100 parts by weight of the at least one water soluble film forming polymer.22. The aqueous composition according to claim 16 , ...

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Номер записи: 99

03-03-2022 дата публикации

Method For Preparing Natural Organic Macromolecular Water Treatment Agent

Номер: US20220062856A1

Автор: Liu Jun, Zhuo Jinming, Zhuo Yuguo

Принадлежит: Hebei University of Environmental Engineering

Method for preparing a natural organic macromolecular water treatment agent including: dissolving amylose corn starch in an alkali solution, stirring for 30 min, to obtain a suspension, freezing the suspension to fully frozen state, melting and dialyzing, to obtain a corn starch dispersion; mixing a modified flax fiber, the dispersion, nano-hybrid silica and distilled water, performing 800 W ultrasonication for 10 min, to obtain a treated suspension; taking an amount of a superabsorbent macromolecular resin with a certain shape, making it absorb water and swell into a solid hydrogel with the certain shape; mixing the solid hydrogel and the treated suspension, static defoaming, loading into a mold and solidifying, drying until the solid hydrogel is completely dehydrated, to obtain a hollow agent; spraying a catalytic degrading agent/toxin degrading agent on the surface of the hollow agent and/or the inner wall of holes thereof, to obtain the target agent.

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Номер записи: 100