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Небесная энциклопедия

Космические корабли и станции, автоматические КА и методы их проектирования, бортовые комплексы управления, системы и средства жизнеобеспечения, особенности технологии производства ракетно-космических систем

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Мониторинг СМИ

Мониторинг СМИ и социальных сетей. Сканирование интернета, новостных сайтов, специализированных контентных площадок на базе мессенджеров. Гибкие настройки фильтров и первоначальных источников.

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Форма поиска

Поддерживает ввод нескольких поисковых фраз (по одной на строку). При поиске обеспечивает поддержку морфологии русского и английского языка
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Применить Всего найдено 848. Отображено 193.
16-07-2003 дата публикации

Isolation methods and appartus

Номер: GB0000313732D0
Автор:
Принадлежит:

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15-08-1977 дата публикации

VERFAHREN ZUR AUTOMATISCHEN STEUERUNG EINES INDUSTRIELLEN CHROMATOGRAPHISCHEN PROZESSES

Номер: ATA875772A
Автор:
Принадлежит:

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15-03-2009 дата публикации

SAMPLE GIVER, IN PARTICULAR FOR THE HIGH SPEED LIQUID CHROMATOGRAPHY

Номер: AT0000423308T
Принадлежит:

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15-12-1986 дата публикации

CHROMATOGRAFIEGERAET AND PROCEDURES FOR ITS ENTERPRISE.

Номер: AT0000023953T
Принадлежит:

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31-03-1994 дата публикации

On-line product identification in a chromatography effluent by subtraction

Номер: AU0000647929B2
Принадлежит:

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14-05-2001 дата публикации

Automated plant extraction method and arrays for high throughput screening

Номер: AU0001453801A
Принадлежит:

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20-08-2001 дата публикации

Mapping of differential display of proteins

Номер: AU0003488001A
Принадлежит:

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05-12-2000 дата публикации

Device for reducing loss of liquid during fraction collection

Номер: AU0004966000A
Принадлежит:

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28-06-2001 дата публикации

SYSTEM AND METHOD FOR AUTOMATED MATCHED ION POLYNUCLEOTIDE CHROMATOGRAPHY

Номер: CA0002393849A1
Принадлежит:

In an extensive Matched Ion Polynucleotide Chromatography (MIPC) system and method, and the computer programs or software associated therewith, the system provides automated options for sample selection, mobile phase gradient selection and control, column and mobile phase temperature control, and fragment collection for a wide variety of MIPC separation processes. MIPC separation processes can be applied to effect size-based separation of DNA fragments, mutation detection, DNA fragment purification, PCR process monitoring and other novel processes. This invention is directed to the system and software which automates many of these procedures, facilitating use of the system to achieve complex separation methods. In one embodiment of the invention, a user specifies a size range of double stranded DNA fragment(s) in a mixture, the software calculates a solvent gradient to elute the fragment(s), and the system performs the chromatographic separation using the calculated gradient. In an embodiment ...

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30-11-1963 дата публикации

Impulsadapter

Номер: CH0000373578A
Принадлежит: CESKOSLOVENSKA AKADEMIE VED

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31-10-1975 дата публикации

Номер: CH0000568087A5
Автор:
Принадлежит: SUOMEN SOKERI OY, SUOMEN SOKERI OSAKEYHTIOE

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29-08-1975 дата публикации

Номер: CH0000565577A5
Автор:
Принадлежит: HEWLETT PACKARD GMBH, HEWLETT-PACKARD GMBH

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15-01-1988 дата публикации

DEVICE FOR THE ALLOCATION A RIESELNDEN OF A SUBSTANCE.

Номер: CH0000663727A5
Автор: ZEMP, GEORG
Принадлежит: CONTRAVES AG

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28-05-2004 дата публикации

Fraction collector, for use in column chromatography, has rows of vessels in holder, slide moving along this which carries filling tube, its position being controlled by sensor which reads bar code strip

Номер: CH0000694001A5
Автор: LEHKY DR. PAVEL
Принадлежит: PAVEL LEHKY DR, Dr Pavel Lehky

Fraction collector, for use in column chromatography, has rows of vessels in a holder (B). A slide (A) moves along this which carries a filling tube, its position being controlled by a sensor which reads a bar code strip (D1, D2).

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23-02-1968 дата публикации

Process of production and measurement of enrichment

Номер: FR0001514094A
Автор:
Принадлежит:

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08-07-2015 дата публикации

샘플을 분석하고 샘플 분획을 수집하기 위한 방법 및 장치

Номер: KR1020150079988A
Принадлежит:

... 본 발명에는 하나 이상의 검출기를 사용하여 샘플을 분석하는 방법 및 장치가 개시되어 있다.

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15-01-2000 дата публикации

PERMEABILITY MEASURING METHOD AND MEASURING DEVICE OF PERMEATED MATERIAL PASSING THROUGH NON-POROUS MEMBRANE

Номер: KR20000001465A
Принадлежит:

PURPOSE: A permeability measure method and a measure device of permeated material passing through a non-porous membrane are provided to measure on-line the changing form according to the time of permeability about the permeated material such as a solution, vapor, gas passing through a non-porous high molecular membrane. CONSTITUTION: A permeability measure method of permeated material passing through a non-porous membrane comprises the steps of:storing liquid supplied solution to be permeated in the supplied solution container(16) and controlling at a temperature of a specific level; permeating the supplied solution in the supplied solution container(16) using a supplying pump; for the permeated material permeated the permeating membrane(20) to pass a mass current measuring instrument(28); measuring the permeating speed of the permeated material; measuring the constitution of the permeated material on line; condensing the permeated material passed through a gas chromatography(38) in a condenser ...

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20-05-2010 дата публикации

COLLECTION SYSTEM FOR PURIFICATION FLOWSTREAMS

Номер: WO2010056313A1
Принадлежит:

A collection system for collecting samples from a flowstream (5) exiting a supercritical fluid chromatography system is provided. The collection system comprises: (i) a first back pressure regulator (10) on the flowstream as it exits the chromatography system, (ii) a gas-liquid separator (30) having a tapered and angled dripper (65), which introduces the flow into the separator at an angle tangential to the separator wall; and (iii) one or more fraction collectors (15), wherein the fraction collector is at a reduced pressure collection point, between 100 bar and atmospheric pressure. A collection system for HPLC is also provided, as well as a process for collection of samples from a flowstream.

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08-04-1999 дата публикации

APPARATUS AND METHOD FOR RADIOACTIVITY MEASUREMENT IN LIQUID CHROMATOGRAPHY

Номер: WO1999017104A1
Автор: LEE, Dian, Y.
Принадлежит:

A stop-flow method and apparatus for measuring radioactivity in a liquid chromatographic eluate in which flow is stopped and resumed so that radioactivity of desired portions of the eluate can be measured accurately in a stationary manner. The sample is passed through a chromatographic column (10) to a radioactivity detector (17) via valve (47) under the control of controller (35). The valve (47) is closed in response to signals from a timer, the radioactivity detector (17) or other detector (12) to stop eluate flow and permit stationary measurement. In a second embodiment, eluate fractions may be stored in a capillary storage device prior to passage to the radioactivity detector (17) for stationary measurement.

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23-12-1999 дата публикации

DEVICE AND METHOD FOR THE LIQUID CHROMATOGRAPHIC SEPARATION OF SUBSTANCE MIXTURES UNDER PRESSURE

Номер: WO1999065587A1
Принадлежит:

The invention relates to a device and method for the liquid chromatographic separation of substance mixtures under pressure. The aim of the invention is to provide a device and method for the liquid chromatographic separation of different types of substance mixtures under pressure with which the substance mixture and the separated samples in the case of less complex substance mixtures can be separated, processed and isolated in less time and in a manner which is less complicated. To this end, a device provided for the liquid chromatographic separation of substance mixtures under pressure is comprised of a sample feeding system (5), pumps (3, 4, 9, 12), a detection system (7), a fraction issuing device (17), a computing unit, and multiple way valves. The inventive device is characterized in that only one separating column (6) and one solid phase extraction unit (10) are coupled in a pressure-stable manner.

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23-08-1966 дата публикации

Номер: US0003267646A1
Автор:
Принадлежит:

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15-12-2005 дата публикации

Single-pass compound purification and analysis

Номер: US2005277199A1
Принадлежит:

The present invention relates to high-throughput compound purification and analysis systems that include representative sample fraction storage components that are structured to at least transiently store representative sample fraction aliquots prior to analysis. In addition, related computer program products and methods are also provided.

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19-02-2014 дата публикации

Preparative liquid chromatograph using plural detectors

Номер: EP1380329B1
Автор: Waki, Hiroaki
Принадлежит: Shimadzu Corporation

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01-11-2006 дата публикации

Fraction collector for composition analysis

Номер: GB0002418157B

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07-01-1976 дата публикации

FRACTION COLLECTOR

Номер: GB0001420423A
Автор:
Принадлежит:

... 1420423 Fraction collector HEWLETT PACKARD LTD 12 Dec 1973 [28 Dec 1972] 57593/73 Heading B1H [Also in Division G1] A fraction collector for collecting the liquid fractions of a liquid chromatography system includes stationary means for mounting a plurality of fraction receivers in spaced relationship around the periphery of a circle, a delivery line for delivering liquid fractions to the receivers, the delivery line having a nozzle and being rotatably mounted whereby the nozzle can move around the circle, and means for rotating the delivery line intermittently whereby the nozzle moves in steps from one receiver to another. The fraction receivers may be test-tubes, or funnel-shaped holes in a suitable insert connected by pipelines to remote receivers. Holes between these intended to receive samples of interest may be connected together to a common receiver.

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19-11-1975 дата публикации

CHROMATOGRAPHIC PROCESSES

Номер: GB0001414795A
Автор:
Принадлежит:

... 1414795 Invert sugar separation process SUOMEN SOKERI OSAKEYHTIO 23 Oct 1972 [27 Oct 1971] 48752/72 Heading C2S [Also in Division B1] Invert sugar is separated into glucose and fructose by chromatography. The angle of rotation and the concentration of the effluent is continuously monitored and the figures fed to a computer which decides where to cut between a glucose fraction, an intermediate fraction which is recycled, and a fructose fraction.

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21-07-1971 дата публикации

IMPROVEMENTS IN OR RELATING TO GAS CHROMATOGRAPHY

Номер: GB0001240121A
Принадлежит:

... 1,240,121. Gas chromatography apparatus. PYE Ltd. 24 Sept, 1968 [30 Sept., 1967; 25 July, 1968], Nos. 44629/67 and 35661/68. Heading B1L. [Also in Division G3]. Separate traps in trap unit TU are presented to the outlet of gas chromatograph column C to isolate desired fractions, the trap changing mechanism being controlled by means of a predetermined punched tape programme in conjunction with means for comparing the output signal of detector D with a reference level, preselected for low, medium or high settings by means of microswitches MS1-3 in pen recorder PR. Trap index controller TC comprises a number of banks of switches (S1A to S6C), any one of which may be selected in sequence by solenoid actuator SA which is advanced by closing selector advance microswitch MS5; when a sample is injected on to the column, sample inject microswitch MS6 is operated and solenoid actuator SA is returned to the first bank of switches. Switches SID to S6D select the operative bank of switches S1A to S6C ...

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05-11-2002 дата публикации

Method and system for carrying out repetitive, preparative chromatography

Номер: AU2002304720A8
Принадлежит:

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29-06-2000 дата публикации

AUTOMATED ON-LINE EVAPORATING LIGHT SCATTERING DETECTION TO QUANTIFY ISOLATED FLUID SAMPLE COMPOUNDS IN MICROTITER PLATE FORMAT

Номер: CA0002356218A1
Принадлежит:

Single pass methods and systems for measuring the total masses of individual compounds present in fluid samples in real time, and particularly for fluid samples prepared in microtiter plate format are provided. Individual compounds are isolated by fluid separation column (14). Portions of the individual compounds isolated by column (14) are analyzed by mass spectrometer (16), which determines their concentration on the basis of their molecular weights, and an evaporative light scattering detector (24), (which determines the total masses of each of the isolated compounds passing therethrough). Total collected masses of the individual compounds are calculated by determining the amount and portion of the isolated compounds diverted into evaporative light scattering detector (24) during a period of fraction collection.

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23-11-2000 дата публикации

DEVICE FOR REDUCING LOSS OF LIQUID DURING FRACTION COLLECTION

Номер: CA0002371565A1
Автор: ANDERSSON, LARS
Принадлежит:

Spillage of liquid during switching of receptacles in a fraction collector is avoided by introducing a device in the flow path between an inlet tubing (6) and a dispensing means (5), said device comprising an expandable chamber (34) that accommodates liquid during the time interval for switching from one receptacle (3) to the next (3').

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09-10-2003 дата публикации

A CHROMATOGRAPHY SYSTEM FOR AUTOMATICALLY SEPARATING DIFFERENT COMPOUNDS IN A SAMPLE

Номер: CA0002480075A1
Принадлежит:

A chromatography system (10) including a chromatography column (18) connected to receive a sample and separate different compounds in the sample, a flow- through detector (10) that outputs a signal indicating the presence of compounds in the sample leaving the column (18), a fraction collector (22) that directs fractions of the sample from the column (18) to separate fraction wells (26), and an electronic controller (28) that receives inputs from the detector (10) and controls the fraction collector (22). The electronic controller (28) monitors the signal from the detector (10) over time and initiates a cut from one well (26) to another at the fraction collector (22) when the signal over time experiences a shoulder where the slope of the signal over time does not change in sign but does change by more than a predetermined amount.

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28-04-1991 дата публикации

COLUMN ANALYZER SYSTEM

Номер: CA0002028689A1
Принадлежит:

COLUMN ANALYZER SYSTEM An analyzer system for automatic column chromatography, and method for its use, includes an array of chromatograph columns and multi-cell cuvettes associated with each column. Chromatographic separation takes place under a constant, low fluid pressure. A pressure system distributes air to each column during chromatographic separation but prevents leakage of air if the column array is partially empty. The multi-cell cuvette collects and separates the eluates associated with a single column. The system provides for automatic removal of caps from the bottoms of the chromatograph columns and provides for automatic optical density reading.

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09-03-2000 дата публикации

FRACTION COLLECTION SYSTEM AND METHOD

Номер: CA0002308309A1
Принадлежит:

A system for separating an aqueous stream of mixed polynucleotides into a series of length-based polynucleotide fractions and collecting one or more of the length-based polynucleotide fractions into separate containers. The system comprises a separation column containing separation media for separating an aqueous stream of mixed polynucleotides into a series of length-based polynucleotide fractions; a container including one or more single-sample containers; an ejection chamber having a separated sample inlet for receiving the length-based polynucleotide fractions, a waste outlet for discharging uncollected sample, and a capillary-sized fraction outlet positioned to discharge a selected length-based polynucleotide fraction into a single-sample container. The system also includes means for effecting discharge of a selected length-based polynucleotide fraction into the separate container. The means for effecting discharge of a selected length-based polynucleotide fraction into a separate ...

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22-02-2017 дата публикации

Chromatography lab system

Номер: CN0106461629A
Принадлежит:

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02-04-1971 дата публикации

Programmed collecting of fractions in - a chromatograph

Номер: FR0002050935A5
Автор: [UNK]
Принадлежит: SP KONSTRUKTORS

An electronic potentiometric recording device's collector wire is driven by a motor, whose speed and direction of rotation can be controlled. A further collector wire is mechanically coupled with the 1st. A commutation switch is provided for the fracton collector of the chromatograph. Potentiometers set the programmes for the collection of fractions. They, together, with the 2nd collector wire, are in a bridge with 4 arms. Thus the potentiometers, the electronic recording device and the 2nd collector wire form a programming unit, whose output is connected wire form a programming unit, whose output is connected with the commutation switch. Controls can be connected by a switch between a pair of opposite corners of the bridge.

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02-12-1994 дата публикации

Automatic device for treatment using column chromatography, and liquid detector usable in such a device

Номер: FR0002705582A1
Принадлежит:

L'invention concerne un dispositif automatique de traitement par chromatographie sur colonne et le détecteur de liquide utilisable dans un tel dispositif. Ce dispositif comprend une colonne 1 remplie de phase solide 3 et munie d'au moins un détecteur de liquide 9, 11 à l'entrée de la colonne. Les réactifs sont introduits dans la colonne par l'intermédiaire d'une tulipe 13 et d'une pompe 15 au moyen d'un ensemble comprenant un doseur 27, une vanne multivoie 29 et des récipients de réactifs 251 , 252 ... 25n . Dans ce dispositif, les moyens de commande d'introduction des réactifs et d'ouverture de la vanne de sortie 7 de la colonne sont asservis au(x) détecteur(s) de liquides 17, 9, 11 de façon à automatiser le fonctionnement en évitant tout mélange de réactifs.

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26-08-1983 дата публикации

DEVICE OF CHROMATOGRAPHY AND PROCESS OF IMPLEMENTATION

Номер: FR0002522154A1
Принадлежит: HORIBA JOBIN YVON SAS

DISPOSITIF DE CHROMATOGRAPHIE ET PROCEDE DE MISE EN OEUVRE. L'INVENTION EST RELATIVE A UN DISPOSITIF DE CHROMATOGRAPHIE PREPARATIVE EN PHASE LIQUIDE COMPRENANT UNE COLONNE SOUS FORME D'UN TUBE CYLINDRIQUE MUNI A SA PARTIE INFERIEURE D'UN COUVERCLE; UN DISPOSITIF DE REMPLISSAGE PR DESTINE A ETRE RELIE PAR UNE BUSE DE COMPRESSION ET COMPRENANT UN VERIN ACTIONNANT UN CORPS SOLIDE NON POREUX PERMETTANT DE COMPRIMER LA PHASE STATIONNAIRE REMPLISSANT LADITE COLONNE PAR L'INTERMEDIAIRE DE LA BUSE DE COMPRESSION; UNE TETE D'INJECTION DESTINEE A ETRE FIXEE SUR LA COLONNE APRES SON REMPLISSAGE C, LADITE TETE D'INJECTION COMPRENANT UNE PAROI INFERIEURE ET UN BOITIER D'INJECTION D'UN DIAMETRE INFERIEUR A LA TETE D'INJECTION MUNI DE PLUSIEURS ARRIVEES LATERALES DE SOLUTE, LADITE TETE D'INJECTION COMPORTANT SUR LA FACE SUPERIEURE UNE ARRIVEE CENTRALE DE SOLVANT ET DES MOYENS PERMETTANT AU SOLVANT DE CONTOURNER LE BOITIER D'INJECTION; UNE POMPE P RELIEE A LADITE TETE D'INJECTION COMPRENANT QUATRE PISTONS ACTIONNES PAR DES CAMES OU DES BIELLES DISPOSEES A 90 LES UNES PAR RAPPORT AUX AUTRES DONT LE SUPPORT N'EST PAS SOLIDAIRE DU BLOC; UN DISPOSITIF DE DETECTION CONSISTANT EN UN MONTAGE EN DOUBLE DETECTION D; UN COLLECTEUR DE FRACTIONS RELIE AU DISPOSITIF DE DETECTION COMPRENANT DEUX COMPARTIMENTS SUPERPOSES. CHROMATOGRAPHY DEVICE AND PROCESS FOR IMPLEMENTATION. THE INVENTION RELATES TO A PREPARATIVE LIQUID PHASE CHROMATOGRAPHY DEVICE INCLUDING A COLUMN IN THE FORM OF A CYLINDRICAL TUBE WITH ITS LOWER PART WITH A COVER; A PR FILLING DEVICE INTENDED TO BE CONNECTED BY A COMPRESSION NOZZLE AND INCLUDING A CYLINDER ACTIVATING A SOLID NON-POROUS BODY ALLOWING TO COMPRESS THE STATIONARY PHASE FILLING THE said COLUMN THROUGH THE COMPRESSION NOZZLE; AN INJECTION HEAD INTENDED TO BE FIXED ON THE COLUMN AFTER ITS FILLING C, THE AID INJECTION HEAD INCLUDING A BOTTOM WALL AND AN INJECTION BOX WITH A DIAMETER LOWER THAN THE INJECTION HEAD ...

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25-02-2021 дата публикации

SAMPLE HANDLING AND DISPATCHING INDIVIDUAL SAMPLE PACKAGES

Номер: US20210055268A1
Принадлежит:

A sampling unit for handling a sample fluid includes a sample container having a length and being configured for receiving and storing the sample fluid, and a sample segment dispatching unit configured for providing a plurality of individual sample packages of the fluidic sample, each contained in a respective volume segment along the length of the sample container, and for individually dispatching each of the plurality of individual sample packages for further processing in a fluid processing unit. 1. A sampling unit for handling a sample fluid , the sample unit comprising:a sample container having a length and being configured to receive and store the sample fluid, wherein a composition of the sample fluid is not homogeneous over the length of the sample container; anda sample segment dispatching unit configured to provide a plurality of individual sample packages of the fluidic sample, each contained in a respective volume segment along the length of the sample container, and to individually dispatch each of the plurality of individual sample packages for further processing in a fluid processing unit.2. The sampling unit of claim 1 , comprising at least one of:the sample container comprises an inlet and an outlet, and the length is between the inlet and the outlet;the sample fluid comprises a plurality of different compounds;the sample fluid comprises a plurality of different compounds having different distributions of concentration over the length of the sample container;the sample fluid comprises a plurality of different compounds, each compound having a respective spatial concentration distribution along the length of the sample container resulting from a previous sample processing selected from the group consisting of: a chromatographic separation, a flow reaction, a chemical reaction, a fermentation, and a sample withdrawal from a process fluid;the sample fluid comprises a plurality of different compounds being pre-fractionated by a previous chromatographic ...

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13-06-2002 дата публикации

Apparatus and method for preparative supercritical fluid chromatography

Номер: US2002070169A1
Автор:
Принадлежит:

A fractionated sample collection process and device having at least one pressurized chamber used to gather and store liquid samples generated from a flow stream containing a mixture of highly compressed gas, compressible liquid, or supercritical fluid and a relatively incompressible liquid. A bank of multiple collection chambers is secured together in a frame to form a cassette unit. Each collection chamber may house a replaceable liner such as a test tube vial, to hold a fractionated liquid phase sample. After filling with sample, a collection chamber is returned to a clean state and ready for refilling with a new sample by manually or automatically replacing the liner. The separation and collection process partitions the liquid phase, containing modifier and dissolved sample components from the gaseous phase components upstream of the collection chamber so that liquid phase has controlled discharge into the collection chamber. Movement and replacement of collection chamber liners to capture ...

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24-07-2019 дата публикации

METHOD AND APPARATUS FOR CHROMATOGRAPH NANO-FLOW FRACTIONATOR

Номер: EP3514530A1
Принадлежит: Thermo Finnigan LLC

A nano-flow fractionator apparatus, comprises: one or more sources of mobile phase solvent; a source of auxiliary solvent; a sample injection valve; a chromatographic column having an inner diameter of less than or equal to 75 micro-meters, a column inlet end and a column outlet end; a solvent fraction delivery line comprising: an inlet end that is configured to receive eluate that is emitted from the column outlet end and an outlet end that is configured to dispense the eluate to each of a plurality of sample fraction containers; a fluid junction configured to receive the eluate that is emitted from the column outlet end and to receive a flow of the auxiliary solvent that is delivered from the source of auxiliary solvent and to deliver the eluate and the flow of auxiliary solvent to the solvent fraction delivery line.

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21-12-2016 дата публикации

AUTOMATED LIQUID CHROMATOGRAPHY SYSTEM WITH A FLUID HANDLING SYSTEM

Номер: EP2440913B1
Принадлежит: GE Healthcare Bio-Sciences AB

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27-08-2008 дата публикации

СПОСОБ ДЛЯ ПОДГОТОВКИ ОБРАЗЦОВ ДЛЯ АНАЛИЗА, УСТРОЙСТВО ДЛЯ ЕГО РЕАЛИЗАЦИИ И МАГАЗИН ДЛЯ ПОДГОТОВКИ ОБРАЗЦОВ ДЛЯ АНАЛИЗА

Номер: RU2332673C2
Принадлежит: ЖИЛЬСОН С.А.С. (FR)

Изобретение относится к способам подготовки образцов для анализа. В устройстве для твердофазной экстракции (SPE), как только все колонки SPE-планшета наполняются жидкостью, иглы взаимодействуют со сцепляющими конструкциями на нажимном элементе для прижима вниз планшета вместе с поджатой вверх подошвой в уплотнительное зацепление с периферической проставкой, окружающей контейнер. Одновременно создается вакуум благодаря соответствующему управлению клапаном, и все колонки одновременно передают жидкость в сливной контейнер. Затем вакуум сбрасывается, иглы входят в зацепление с углублениями для перемещения каретки над сборным контейнером, и аналогичная рабочая последовательность возобновляется. Технический результат - устранение загрязнения колонки при ускорении пробоподготовки. 3 н. и 22 з.п. ф-лы, 17 ил.

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27-01-2006 дата публикации

СПОСОБЫ, МАГАЗИН И УСТРОЙСТВО ДЛЯ ПОДГОТОВКИ ОБРАЗЦОВ ДЛЯ АНАЛИЗА

Номер: RU2005127585A
Принадлежит:

... 1. Способ подготовки образцов для анализа, содержащий этапы, в соответствии с которыми впрыскивают, по меньшей мере, одну жидкость в отдельные колонки подвижного планшета посредством, по меньшей мере, одной подвижной впрыскивающей иглы; перемещают планшет между, по меньшей мере, двумя рабочими позициями перемещением, по меньшей мере, одной упомянутой иглы, когда, по меньшей мере, одна игла связана, по меньшей мере, непрямым взаимным зацеплением с упомянутым планшетом; отличающийся тем, что взаимное зацепление имеет место между иглами и зацепляющими конструкциями вне колонок. 2. Способ по п.1, отличающийся тем, что взаимное зацепление осуществляется между наконечником иглы и углублением, которое имеет приводную связь с планшетом. 3. Способ по п.1 или 2, отличающийся тем, что для разных перемещений планшета, взаимное зацепление осуществляется, соответственно, в разных местах относительно планшета. 4. Способ по п.2, отличающийся тем, что для разных перемещений планшета, взаимное зацепление ...

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23-05-1985 дата публикации

Коллектор фракций

Номер: SU1157446A1
Принадлежит:

... 1. КОЛЛЕКТОР ФРАКЦИЙ, содержащий кортус с держателями пробирок, адаптер, направляпщне с ползунами и фиксатором поперечного перемещения адаптера, механизм . продольного перемещения адаптера с фиксатором, установленный на указанных ползунах, и блок управления, отличающийся тем, что, с целью упрощения конструкции, держатели пробирок установлены один -. над другим и наклонно к горизонтальной плоскости, а направляюв ие установлены вертикально с двух сторон корпуса. 2.Коллектор фракций по п«, отличающийся тем, что ,на направляющих выполнены пазы и выступы , длина которых соответствует величине перемещения адаптера с держателя на другой, i и расположены они так, что выступам на одной стороне направляющей соотвествуют пазы на другой направлякгщей , взаимодействующие с фиксатором, вьшолненным в виде стержня, установленного концами в ползунах 3.Коллектор фракций по п.1, отличающий с я тем, .что адаптер вьтолнен из эластичной трубО1 ки. sl 4 О ...

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28-03-1974 дата публикации

Gas chromatographic analysis - branched stream of separated constituents is retained on support strip for direct comparison with chromatogram

Номер: DE0002246836A1
Принадлежит:

A method of gas chromatographic analysis of samples operates by breadking down the sample in a separation column into its separate constituents or compounds, so that these leave the column in succession; the constituents or compounds are identified in a detector, the detector signals being recorded in the form of a graph on a moving chromatogram sheet, the graph having peaks corresponding to the separate cpds. A partial stream is branched off from the flow leaving the separation column and is directed towards a support strip which is moved synchronously with the chromatogram sheet. This support strip pref. has a coating of an absorbing material. Pref., the support strip is of Al foil coated with alumina or silica gel. The method enables a direct comparison to be made between the peaks, indicating individual features on the chromatogram and the corresponding portions of material retained on the strip.

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24-11-1965 дата публикации

Apparatus for collecting fractions separated by gas-chromatography

Номер: GB0001010767A
Принадлежит:

... 1,010,767. Automatically collecting gas chromatography fractions. IMPERIAL CHEMICAL INDUSTRIES Ltd. Jan. 8, 1964 [Jan. 29, 1963], No. 3627/63. Heading B1L. An apparatus for collecting gas chromatography fractions comprises a detector which feeds signals to a recorder to give a chromatogram, a two position switch actuated by the recorder at any desired level rising or falling on the chromatogram. which switch is connected to another two position switch in such a way that an electric motor can be switched on or off by the first switch irrespective of the position of the second, the electric motor driving a multi-station stop-dwell-go mechanism which is connected to a rotary valve assembly having a stationary upper face with an inlet port leading to the discharge end of the detector and a lower rotating member having a plurality of exit ports which are aligned sequentially and automatically by the apparatus with the inlet port according to the fractions which emerge from the column. In a specific ...

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24-11-1971 дата публикации

ANALYTICAL APPARATUS

Номер: GB0001254708A
Автор:
Принадлежит:

... 1,254,708. Analysis; chromatography. TECHNICON CORP. 26 Nov., 1968 [29 Nov., 1967], No. 56138/68. Heading B1X. [Also in Division G1] An analytical apparatus for continuously treating a flowing stream, e.g. of protein, for chemical analysis comprises a liquid chromatography system and a colorimeter which is used as an analyzer and incorporates a gas segment detector to provide a signal to shut down the apparatus if liquid flow in the apparatus falls below or rises above the normal value, thus protecting the apparatus from possible damage. Fig. 2 illustrates a suitable colorimeter arrangement in which effluent from a chromatography column mixed with colour producing reagents and segmentised by gas segments is passed through passageway 110 in colorimeter 100, and peristaltic pump 104 is adjusted so that it pumps out only liquid through passages 106+116 for analysis, and gas out through leg 122. If the flow is normal only liquid will pass. out through tube 128 past bubble detector flow cell ...

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15-01-1997 дата публикации

PRODUCT INFORMATION IN CHROMATOGRAPHI EFFLUENTEN BY DIFFERENCE FORMATION

Номер: AT0000147281T
Принадлежит:

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15-08-2010 дата публикации

PLATFORM FOR PROTEIN PROFILING

Номер: AT0000476654T
Принадлежит:

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20-10-2003 дата публикации

Automatic sample collector

Номер: AU2003229564A8
Принадлежит:

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02-04-2015 дата публикации

Methods and apparatus for analyzing samples and collecting sample fractions

Номер: AU2013228049B2
Принадлежит:

Methods and apparatus for analyzing a sample using at least one detector are disclosed.

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01-02-2011 дата публикации

APPARATUS FOR ASSAY, SYNTHESIS AND STORAGE, AND METHODS OF MANUFACTURE, USE, AND MANIPULATION THEREOF

Номер: CA0002425476C
Принадлежит: BIOTROVE, INC.

The invention features methods of making devices, or "platens" having a high- density array of through-holes, as well as methods of cleaning and refurbishing the surfaces of the platens. The invention further features methods of making high-density arrays of chemical, biochemical, and biological compounds, having many advantages over conventional, lower-density arrays. The invention includes methods by which many physical, chemical or biological transformations can be implemented in serial or in parallel within each addressable through-hole of the devices. Additionally, the invention includes methods of analizying the contents of the array, including assaying of physical properties of the samples. In various embodiments, the reagents can be contained within the through-holes by capillary action, attached to the walls of the through-hole. The porous material can be, for example, a gel, a bead, sintered glass, or particulate matter, or can be the inner wall of a ghrough-hole that has been ...

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09-09-2005 дата публикации

Installation for separating the components of a fluid by pressurised liquid chromatography where some of the separated components are collected or rejected

Номер: FR0002867089A1
Принадлежит: BIONISIS SA

The components are separated into a number of parallel separation channels (A, B, C.). A first controller (22) selectively connects the outlet of the separation channel(s) to one of two parallel means (20) of temporary storage and a second controller (24) connects the temporary storage to means of collection (28) or rejection (30) depending on the components detected (by 16) in the channels : The installation includes a movable arm (32) carrying the outlets (26) from the means of storage, and means of controlling the movement of this arm in translation above the means of collection, for example a micro-well plate, a series of tubes, reaction well bars or similar. A third means of control selectively connects the inlets to the means of temporary storage to a supply of gas or liquid under pressure to ensure continuous transfer of the components in the temporary storage to the means of collection or rejection. The first and second means of control are electrovalves and/or control valves. The means of detecting fluid in the separation channels comprises cells (16), for example of the type measuring the adsorption of a light ray. The installation also includes equipment for measuring a characteristic property of the components passing through the separation channels, for example their molecular mass, and means (10, 12, 44) of supplying this equipment with a train of samples from the separation channel. The installation also includes means of sampling a predetermined or programmable quantity of component in each channel, with the means of depositing these samples in a pipe connecting in series the means of sampling for the measurement cells and means (44) of transporting the sampled quantities in the pipe (12) to the measuring equipment (14). The means of transport is a circulating pump connected to the end of the pipe opposite to the measuring device. The means of sampling includes electrovalves. A means of sampling is branched on each separation channel and comprises a ...

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26-08-1983 дата публикации

DISPOSITIF DE CHROMATOGRAPHIE ET PROCEDE DE MISE EN OEUVRE

Номер: FR0002522154A
Принадлежит:

DISPOSITIF DE CHROMATOGRAPHIE ET PROCEDE DE MISE EN OEUVRE. L'INVENTION EST RELATIVE A UN DISPOSITIF DE CHROMATOGRAPHIE PREPARATIVE EN PHASE LIQUIDE COMPRENANT UNE COLONNE SOUS FORME D'UN TUBE CYLINDRIQUE MUNI A SA PARTIE INFERIEURE D'UN COUVERCLE; UN DISPOSITIF DE REMPLISSAGE PR DESTINE A ETRE RELIE PAR UNE BUSE DE COMPRESSION ET COMPRENANT UN VERIN ACTIONNANT UN CORPS SOLIDE NON POREUX PERMETTANT DE COMPRIMER LA PHASE STATIONNAIRE REMPLISSANT LADITE COLONNE PAR L'INTERMEDIAIRE DE LA BUSE DE COMPRESSION; UNE TETE D'INJECTION DESTINEE A ETRE FIXEE SUR LA COLONNE APRES SON REMPLISSAGE C, LADITE TETE D'INJECTION COMPRENANT UNE PAROI INFERIEURE ET UN BOITIER D'INJECTION D'UN DIAMETRE INFERIEUR A LA TETE D'INJECTION MUNI DE PLUSIEURS ARRIVEES LATERALES DE SOLUTE, LADITE TETE D'INJECTION COMPORTANT SUR LA FACE SUPERIEURE UNE ARRIVEE CENTRALE DE SOLVANT ET DES MOYENS PERMETTANT AU SOLVANT DE CONTOURNER LE BOITIER D'INJECTION; UNE POMPE P RELIEE A LADITE TETE D'INJECTION COMPRENANT QUATRE PISTONS ...

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05-08-2015 дата публикации

Номер: KR1020150090283A
Автор:
Принадлежит:

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05-07-2018 дата публикации

SINGLE-USE, DISPOSABLE HIGH-PRESSURE LIQUID CHROMATOGRAPHY COLUMNS FOR HIGH-THROUGHPUT ANALYSIS

Номер: WO2018126064A2
Автор: OZBAL, Can
Принадлежит:

A device for separating one or more molecules of interest in a liquid specimen including a monolithic body defining a fractionation column. The column includes an inlet opening at a proximal end of the fractionation column; an outlet opening at a distal, opposite end of the fractionation column; a solid phase chamber positioned between the inlet opening and the outlet opening; a specimen introduction area adjacent a proximal end of the solid phase chamber; an analyte exit area adjacent a distal end of the solid phase chamber; an inlet chamber adjacent the inlet opening that tapers into the specimen introduction area; and an outlet chamber that extends from the analyte exit area to the outlet opening. A metered amount of solid phase packed within the solid phase chamber between a first porous frit and a second porous frit of the solid phase chamber.

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14-01-1999 дата публикации

PROCESS FOR DETERMINING THE NUMBER OF COMPONENTS IN PEAKS, BANDS AND SIGNALS OF CHROMATOGRAMS, ELECTROGRAMS AND SPECTROGRAMS OF ALL TYPES

Номер: WO1999001760A1
Принадлежит:

A process is disclosed for determining the number of components in peaks, bands and signals of chromatograms, electrograms and spectrograms of all types obtained for purposes of analysis and substance separation in spectrograms of all types wherever energy-correlated measurement values as a function of an evolving parameter are formed and decomposed again. The problem addressed by the invention is that of designing a simple process. This problem is solved in that the different energy-correlated measurement values of a family of such measurement values produced from such a parameter are mutually related, so that characteristic geometric figures are obtained in which the originating evolving parameters are no longer contained. The thus obtained figures are gradually reduced, depending on their complexity, into straight lines, then into points. The number of components which contribute to the peaks and thus the composition of the total spectrogram in terms of the elements that make it up are ...

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12-03-2020 дата публикации

GAS CHROMATOGRAPH DEVICE AND GAS CHROMATOGRAPH DEVICE ANALYSIS SUPPORT METHOD

Номер: WO2020049614A1
Принадлежит:

The gas chromatograph device (100) is equipped with a calculation unit (2) that acquires information on a flow path (36) between a branch unit (33) and a detector (34) and information identifying the type of detector connected to the flow path and calculates at least one of the flow rate of a gas in the flow path, the linear velocity of a gas in the flow path, and the pressure of the branch unit based on the information acquired.

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29-01-1985 дата публикации

Sample treatment device

Номер: US0004495975A1
Принадлежит: Pharmacia AB

A device for treating samples, for example collection of fractions from a chromatographic separation process, comprises a series of test containers (11), a treatment unit (5) and an apparatus (4) for creating relative motion between the test containers and the treatment unit. The treatment unit passes the test containers in sequence and subjects the same to one or more treatment steps. According to the invention the test tubes are detected and their position indicated by a sensor (9) which is arranged to trigger the treatment step or steps when contacting a given area on the respective test container (11), especially by the resilient biasing of a spring (13).

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10-08-1993 дата публикации

ON-LINE PRODUCT IDENTIFICATION IN A CHROMATOGRAPHY EFFLUENT BY SUBTRACTION

Номер: US0005234586A
Автор:
Принадлежит:

Disclosed is a method and apparatus for the rapid identification of a solute of interest in an effluent stream. The method involves separation of the solutes in the effluent and identification of a particular solute of interest by its selective subtraction from the effluent stream.

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05-09-2002 дата публикации

Analysis system and analysis method

Номер: US2002122745A1
Автор:
Принадлежит:

An analysis system which permits sample pretreatment which comprises: a sample rack; a sample container supply, a sample dispenser, a solvent-removing evaporator, a solvent dispenser for dispensing a second solvent, a sample-stirring means, a sample aspirating-and-transferring means, a sample recovery means, a sample container recovery means, and a control means for controlling the aforementioned various means.

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04-08-2004 дата публикации

Methods, rack and device for preparing samples for analysis

Номер: EP0001443330A1
Автор: Kubacki, Michel
Принадлежит:

In a solid phase extraction (SPE) device, once all the columns 31 of the SPE plate 29 are filled with liquid (81), the needles (47) cooperate with engagement formations (49) on a pusher element (24) for pushing down the plate (29) together with an upwardly biased shoe (23) into sealing engagement with a peripheral spacer (13) surrounding a container (11). Simultaneously, vacuum (78) is applied by appropriate control of a valve (76) and all the columns simultaneously transfer liquid into the drain container. Then, vacuum is released, needles (47) engage recesses (51) to move a carriage (20) above a collect container (12) and a similar prosecution is resumed.

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16-12-2004 дата публикации

FRACTIONAL COLLECTION DEVICE FOR LIQUID CHROMATOGRAPHY

Номер: JP2004354222A
Принадлежит:

PROBLEM TO BE SOLVED: To enable the preparation of a plurality of sample containers by enabling the automatic continuous execution of a collecting work. SOLUTION: This device comprises a storage part 6 capable of storing a plurality of sample containers, and a carrying mechanism 3 adapted so as to be capable of performing the taking-out or replacement of a sample container in the storage part 6 followed by carrying, and positioning the sample container under a nozzle 22 in order to drop a liquid to the sample container. COPYRIGHT: (C)2005,JPO&NCIPI ...

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23-02-1988 дата публикации

Коллектор фракций

Номер: SU1376043A1
Принадлежит:

Изобретение относится к конструкциям коллекторов фракций и может быть использовано для сбора фракций в жидкостном хроматографе. Целью изобретения является упрощение конструкции коллектора. Коллектор дополнительно снабжен измерителем-ограничителем количества раствора, отбираемого в пробирку, и выполнен в виде подпружиненного кронштейна, взаимодействующего с пробиркой и штативом. Пробирки свободно установлены в гнездах штатива, свободно подвешенного на оси. Точка подвеса штатива расположена выше его центра тяжести. Привод штатива является магнитной мешалкой. 1 ил. с S сл ...

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01-10-2015 дата публикации

VERFAHREN ZUM SAMMELN VON FRAKTIONEN FÜR EIN FLÜSSIGKEITSCHROMATOGRAPHIESYSTEM

Номер: DE102015102752A1
Принадлежит:

Beschrieben werden ein Fraktionssammler und ein Verfahren zum Sammeln von Fraktionen für ein Flüssigkeitschromatographiesystem. Das Verfahren umfasst das Umlenken eines Flüssigkeitschromatographiesystemflusses von einem Abfallkanal in ein Sammelrohr bei einem Beginn eines Fraktionssammelfensters und das Sammeln des Systemflusses, der von dem Sammelrohr während des Fraktionssammelfensters abgegeben wird. Am Ende des Fensters wird der Systemfluss zu dem Abfallkanal umgelenkt und ein Fluss eines Waschlösungsmittels wird dem Sammelrohr zugeführt, um in dem Sammelrohr am Ende des Fensters verbleibende Flüssigkeit von dem Sammelrohr abzugeben. Das Verfahren kann die Menge der gesammelten Fraktionen erhöhen und es kann Kreuzkontamination einer nachfolgend gesammelten Fraktion verringern oder eliminieren. Das Verfahren ist zweckdienlich für Anwendungen im analytischen Maßstab, wo die gesammelten Fraktionen Volumina aufweisen können, die durch eine begrenzte Anzahl von Tröpfchen definiert werden ...

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15-05-2009 дата публикации

PROCEDURE AND DEVICE FOR THE ULLAGE REDUCTION DURING PARLIAMENTARY GROUP COLLECTION

Номер: AT0000429636T
Принадлежит:

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07-06-2007 дата публикации

Sample injector, in particular for high-power liquid chromatography

Номер: AU2006319577A2
Принадлежит:

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25-07-2013 дата публикации

Collection System For Purification Flowstreams

Номер: US20130186831A1
Принадлежит: THAR INSTRUMENTS, INC.

A collection system for collecting samples from a flowstream () exiting a supercritical fluid chromatography system is provided. The collection system comprises: (i) a first back pressure regulator () on the flowstream as it exits the chromatography system, (ii) a gas-liquid separator () having a tapered and angled dripper (), which introduces the flow into the separator at an angle tangential to the separator wall; and (iii) one or more fraction collectors (), wherein the fraction collector is at a reduced pressure collection point, between 100 bar and atmospheric pressure. A collection system for HPLC is also provided, as well as a process for collection of samples from a flowstream. 1. A collection system for continuous collections of fractions from a flowstream exiting a supercritical fluid chromatography system , the collection system comprising:(i) a first back pressure regulator on the flowstream as it exits the chromatography system;(ii) a gas-liquid separator having a tapered and angled dripper, which introduces the flow into the separator at an angle tangential to the separator wall; and(iii) one or more fraction collectors, wherein the fraction collector is at a reduced pressure collection point, between 100 bar and atmospheric pressure.2. The collection system of claim 1 , further comprising a solvent make-up pump on the flowstream following the first back pressure regulator.3. The collection system of claim 1 , further comprising a heat exchanger on the flowstream following the first back pressure regulator.4. The collection system of claim 1 , further comprising a second back-pressure regulator placed on a gas line that exits from the gas-liquid separator.5. The collection system of claim 1 , further comprising a separator rinse pump.6. The collection system of claim 1 , wherein the angle of the dripper is between 10 and 80 degrees from vertical.7. The collection system of claim 1 , wherein the ratio of the diameter of the dripper outlet to the ...

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08-08-2013 дата публикации

SAMPLE PROCESSING SYSTEM

Номер: US20130202486A1
Принадлежит:

This invention provides a sample processing system in which only one sample container is rested in one holder, the system being contemplated to prevent a mix-up of samples from occurring. 1. A sample processing system comprising:a conveyance line that conveys a holder between a labeling unit and a aliquoter unit; anda control unit that controls the labeling unit and the aliquoter unit; wherein:one primary-sample container or secondary-sample container is held in one holder;the labeling unit includesa first identifier-reading device that reads an identifier of the holder holding a primary-sample container conveyed by the conveyance line,a printer that prints a label based on information from the control unit as well as on the identifier, read by the first identifier-reading device, of the holder holding the primary-sample container, and affixes the label to a secondary-sample container,a mounting mechanism that mounts the labeled secondary-sample container in a holder, anda second identifier-reading device that reads an identifier of the holder having the secondary-sample container mounted therein; andthe aliquoter unit includesa third identifier-reading device that reads the identifier of the holder conveyed from the labeling unit by the conveyance line and having the primary-sample container mounted therein,a fourth identifier-reading device that reads the identifier of the holder conveyed from the labeling unit by the conveyance line and having the secondary-sample container mounted therein, anda dispenser that dispenses a sample from the primary-sample container conveyed from the labeling unit by the conveyance line into the secondary-sample container conveyed from the labeling unit by the conveyance line.2. The sample processing system according to claim 1 , wherein:the control unit includes a collator adapted to check for matching between the identifier, read by the third identifier-reading device, of the holder holding the primary-sample container, and the ...

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26-12-2013 дата публикации

FLUID SAMPLING APPARATUS AND COLLECTOR PAD SPLITTER

Номер: US20130344615A1
Принадлежит:

A fluid sampling apparatus having a container and a splitter disposed in the container. The splitter is operative for dividing an absorbent pad of a sample collector into two portions. The splitter may have a base and clamping arrangement connected to the base. The clamping arrangement is operative for clamping onto a first portion of the absorbent pad so that the first portion of the absorbent pad can be separated from a second portion of the absorbent pad by pulling the sample collector away from the splitter. 1. A device for dividing an absorbent pad of a sample collector into two portions , the device comprising a clamping arrangement for clamping onto a first portion of the absorbent pad so that the first portion of the absorbent pad can be separated from a second portion of the absorbent pad by pulling the sample collector away from the device.2. The device according to claim 1 , further comprising a base member for supporting the clamping arrangement.3. The device according to claim 2 , wherein the base member has an annular shape.4. The device according to claim 2 , wherein the clamping arrangement includes a clamping member.5. The device according to claim 4 , wherein the clamping member is C-shaped.6. The device according to claim 4 , further comprising a resilient arm member connecting the clamping member to the base member.7. The device according to claim 4 , wherein the clamping member includes a beveled leading edge surface.8. The device according to claim 4 , wherein the base member defines an opening with opposing ear portions.9. The device according to claim 8 , wherein the clamping arrangement further includes another clamping member and wherein the ear portions align with a gap between the clamping members.10. The device according to claim 8 , wherein the ear members each have a chamfered edge.11. A fluid sampling apparatus comprising:a container; anda splitter disposed in the container, the splitter for dividing an absorbent pad of a sample ...

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20-03-2014 дата публикации

BLOOD COMPONENT SAMPLING SYSTEM AND BLOOD PROCESSING SYSTEMS AND METHODS EMPLOYING SAME

Номер: US20140080113A1
Принадлежит: Fenwal, Inc.

A blood component sampling system and method are disclosed. The system is pre-connected and includes a collected blood component container and a reservoir having substantially fixed volume and at least one volumetric indicator indicating a selected volume and a sample container docking station configured to cooperate with a sample collection container. The system and method provide ease of sampling with reduced risk of contamination. 1. A pre-connected sterile blood component sampling system comprising:a collected blood component container;at least one reservoir having substantially fixed volume, at least one volumetric indicator indicating a selected volume within the reservoir;a sample container docking station configured to cooperate with a sample collection container;a first fluid flow path selectively communicating between the blood component container and the at least one reservoir;a second fluid flow path selectively communicating between the at least one reservoir and the docking station; andwhereby a blood component sample of selected volume may be transferred from the collected blood component container to the reservoir and from the reservoir to docking station for withdrawal into a sample collection container.2. The system of further comprising a blood processing circuit for separating the collected blood component from whole blood.3. The system of wherein the at least one reservoir comprises a rigid container.4. The system of wherein the at least one reservoir comprises a flexible container including a constraint that substantially fixes the maximum volume of the container.5. The system of further comprising a valve between the blood component container and the at least one reservoir.6. The system of further comprising a valve between the at least one reservoir and the sample container docking station.7. The system of in which the volumetric indicator is configured to indicate a volume corresponding to one or more selected volumetric sample sizes to ...

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06-01-2022 дата публикации

A Fraction Collection System and Method

Номер: US20220001300A1
Автор: Stafstrom Nils
Принадлежит:

A method for fraction collection and a fraction collection system () comprising: —a dispensing device () including an outlet () configured for dispensing fractions of a liquid received from a connected system; —plural receptacles () configured for receiving one or more of said fractions, wherein the receptacles () and the dispensing device () are movable in relation to each other into a number of different positions such that the dispensing device () is capable of dispensing a respective fraction of said liquid into one or more of the receptacles (); —a waste collection device (), which is arranged in the fraction collection system () such that it is movable into at least a first and a second position wherein, in said first position, an inlet () of the waste collection device () is positioned below the outlet () of the dispensing device () such that liquid being dispensed from the outlet () of the dispensing device () is received in the waste collection device () and wherein, in the second position, the inlet () of the waste collection device () is not positioned below the outlet () of the dispensing device () such that fractions being dispensed from the dispensing device () can be received in one or more of the receptacles (). 1. A fraction collection system comprising:a dispensing device including an outlet configured for dispensing fractions of a liquid received from a connected system;plural receptacles configured for receiving one or more of said fractions, wherein the receptacles the dispensing device are movable in relation to each other into a number of different positions such that the dispensing device is capable of dispensing a respective fraction of said liquid into one or more of the receptacles;a waste collection device, which is arranged in the fraction collection system such that it is movable into at least a first and a second position wherein, in said first position, an inlet of the waste collection device is positioned below the outlet of the ...

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18-01-2018 дата публикации

IMPACT CENTRIFUGAL SEPARATOR AND ASSOCIATED METHODS FOR FRACTION COLLECTION IN SUPERCRITICAL FLUID SYSTEMS

Номер: US20180015390A1
Автор: Wikfors Edwin E.
Принадлежит:

A separator (e.g. an impact centrifugal separator) is for use in collection of liquid portions of a bi-phasic flowstream in a supercritical fluid system. A separator chamber defines an interior space, surrounded by a spiral channel and that has an exit at a lower portion of the separator chamber. A flowstream director (e.g. an entry lube) focuses the flowstream so that the flowstream impacts a wail of the spiral channel at an angle that promotes coalescence of the liquid component. The spiral channel may promote further coalescence of the liquid portions within the constraining spiral channel after impact. A central director may be included in the interior space of the separator chamber to promote flow of the gaseous component toward the exit. A dripper may be included in fluid communication with the spiral channel, for example, in the exit and to direct the coalesced liquid into a collection vessel. 1. A separator for use in collection of liquid portions of a bi-phasic flowstream in a supercritical fluid system , the bi-phasic flowstream including a gaseous and liquid component , the impact centrifugal separator comprising:a separator chamber defining an interior space surrounded by a spiral channel that is open to the interior space, the interior space having an exit at a lower portion of the separator chamber, anda flowstream director configured to focus the bi-phasic flowstream into the spiral channel so that the bi-phasic flowstream impacts a wall of the spiral channel at an angle that promotes coalescence of the liquid component within the spiral channel.2. The impact centrifugal separator of claim 1 , wherein the flowstream director comprises an entry tube claim 1 , having a distal end claim 1 , entering the separator chamber so that the bi-phasic flowstream leaving the distal end is focused and impacts the wall of the spiral channel at an angle that promotes coalescence of the liquid component within the constraining spiral channel.3. The impact centrifugal ...

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17-01-2019 дата публикации

UNIT FOR NON-CONTINUOUS SAMPLE FRACTIONATION AND INTEGRATION, AND DUAL ONLINE MULTIFUNCTIONAL LIQUID CHROMATOGRAPHY DEVICE HAVING SAME

Номер: US20190017974A1

Disclosed are non-continuous sample fractionating and concatenating device and a dual online multidimensional liquid chromatography system having the same. The non-continuous sample fractionating and concatenating device according to an embodiment of the present disclosure includes a sample supply module which supplies a sample to be analyzed, and a sample fractionation module connected to the sample supply module, and which is continuously supplied with the sample, sets a plurality of unit sample supply times obtained by equally dividing a total sample supply time during which the sample is supplied from the sample supply module, sets a plurality of unit fractionation intervals obtained by equally dividing each of the plurality of unit sample supply times, and concatenates and stores the sample supplied during corresponding unit fractionation intervals within each unit sample supply time to acquire a plurality of fractions. 1. A non-continuous sample fractionating and concatenating device , comprising:a sample supply module which supplies a sample to be analyzed; anda sample fractionation module connected to the sample supply module, and which is continuously supplied with the sample, sets a plurality of unit sample supply times obtained by equally dividing a total sample supply time during which the sample is supplied from the sample supply module, sets a plurality of unit fractionation intervals obtained by equally dividing each of the plurality of unit sample supply times, and concatenates and stores the sample supplied during corresponding unit fractionation intervals within each unit sample supply time to acquire a plurality of fractions.2. The non-continuous sample fractionating and concatenating device according to claim 1 , wherein the sample fractionation module includes:a first fractionation valve connected to the sample supply module, into which the sample is introduced;a second fractionation valve provided adjacent to the first fractionation valve; anda ...

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17-02-2022 дата публикации

NON-CONTIGUOUS SAMPLE FRACTIONATING AND CONCATENATING DEVICE AND DUAL ONLINE MULTIDIMENSIONAL LIQUID CHROMATOGRAPHY SYSTEM HAVING THE SAME

Номер: US20220050087A1

Disclosed are non-contiguous sample fractionating and concatenating device and a dual online multidimensional liquid chromatography system having the same. The non-contiguous sample fractionating and concatenating device according to an embodiment of the present disclosure includes a sample supply module which supplies a sample to be analyzed, and a sample fractionation module connected to the sample supply module, and which is continuously supplied with the sample, sets a plurality of unit sample supply times obtained by equally dividing a total sample supply time during which the sample is supplied from the sample supply module, sets a plurality of unit fractionation intervals obtained by equally dividing each of the plurality of unit sample supply times, and concatenates and stores the sample supplied during corresponding unit fractionation intervals within each unit sample supply time to acquire a plurality of fractions. 1. A non-contiguous sample fractionating and concatenating device , comprising:a sample supply module which supplies a sample to be analyzed; anda sample fractionation module connected to the sample supply module, and which is continuously supplied with the sample, sets a plurality of unit sample supply times obtained by equally dividing a total sample supply time during which the sample is supplied from the sample supply module, sets a plurality of unit fractionation intervals obtained by equally dividing each of the plurality of unit sample supply times, and concatenates and stores the sample supplied during corresponding unit fractionation intervals within each unit sample supply time to acquire a plurality of fractions.2. The non-contiguous sample fractionating and concatenating device according to claim 1 , wherein the sample fractionation module includes:a first fractionation valve connected to the sample supply module, into which the sample is introduced;a second fractionation valve provided adjacent to the first fractionation valve; anda ...

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04-02-2021 дата публикации

LIQUID WASTE MONITORING DEVICE

Номер: US20210033501A1
Автор: ANDO Shotaro
Принадлежит:

Liquid waste is temporarily received by a liquid waste receiver that is provided on a discharge path for liquid waste generated in an analyzer to a liquid waste tank. An outflow liquid receiver is arranged adjacent to the liquid waste receiver, the liquid waste receiver and the outflow liquid receiver are partitioned by a partition having a certain height, and a liquid sensor is arranged in the outflow liquid receiver. In a case where an abnormality occurs in discharging of the liquid waste, the liquid waste accumulated in the liquid waste receiver flows over the partition to flow into the outflow liquid receiver, and is detected by the liquid sensor. Because the liquid waste flows into the outflow liquid receiver only in a case where an abnormality occurs in discharging of the liquid waste, an abnormality in discharging of the liquid waste can be detected by the liquid sensor. 1. A liquid waste monitoring device comprising:a liquid waste receiver that is provided on a discharge path for a liquid waste sent from at least one analyzer that constitutes an analysis system for carrying out an analysis using liquid, and is used to receive the liquid waste temporarily and discharge the liquid waste;an outflow liquid receiver that is provided with a partition provided between the outflow liquid receiver and the liquid waste receiver, and is used to receive a liquid waste that has flowed over the partition to flow out from the liquid waste receiver; anda liquid sensor that is provided in the outflow liquid receiver and is used to detect a liquid waste that has flowed out from the liquid waste receiver,whereinthe outflow liquid receiver is configured to receive a leak liquid in the analyzer, and the leak liquid that has flowed into the outflow receiver is detected by the liquid sensor or a separately provided second liquid sensor.2. The liquid waste monitoring device according to claim 1 , whereinthe liquid waste receiver and the outflow liquid receiver are sections ...

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25-02-2016 дата публикации

Systems and methods for aseptic sampling

Номер: US20160053296A1
Принадлежит: General Electric Co

A sampling assembly configured to be coupled to a sample source is provided. The sampling assembly is configured to facilitate aseptic sampling at one or more instances in time. The sampling assembly includes a first conduit having a first port and a second port, where the first port is configured to be coupled to the sample source, and where the second port is configured to be hermetically sealed. The sampling assembly further includes a plurality of sub-conduits having corresponding sub-ports, where each of the plurality of sub-conduits is operatively coupled to the first conduit at respective connection points, and where each of the sub-ports is in fluidic communication with the first conduit. Moreover, the sampling assembly includes a plurality of sampling kits, where each sampling kit of the plurality of sampling kits is operatively connected to a respective sub-port of a corresponding sub-conduit.

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15-05-2014 дата публикации

SCREENING DEVICE FOR ANALYSIS OF BODILY FLUIDS

Номер: US20140134073A1
Принадлежит:

A screening device for testing bodily fluids for the presence of certain constituents. The device can include a planar front face through which all of the test strips are viewed. The device also includes an inclined surface that directs the fluid under test to test strips with more efficiency, and partitions the fluid that is directed to a given test strip to better assure that the test strip receives an adequate amount of bodily fluid for a valid analysis. In one embodiment, the device includes a three-dimensional gasket that creates a pressurized environment upon insertion of the sampling stem for improved diffusion of the bodily fluid into the test strips. 1. A device for testing a sample of bodily fluid , comprising:a cup including a plurality of sides extending upward from a containment bottom, said plurality of sides and said containment bottom defining a cavity, said containment bottom including an inclined surface that intersects each of said plurality of sides, said inclined surface intersecting a first side of said plurality of sides along a junction line, said junction line being located at a lowermost extremity of said cavity when the cup is in an upright position, said inclined surface and said first side defining an acute angle therebetween, said plurality of sides defining an upper perimeter of said cup, said containment bottom including a pedestal portion that extends upwards from said inclined surface, said pedestal portion including a top face having a perimeter that is substantially normal to said insertion axis;a holder disposed in said cavity of said cup, said holder including a front face adjacent said first side of said cup, said front face including a plurality of parallel ribs that define a plurality of parallel elongate channels, said plurality of parallel elongate channels each defining a channel axis that extends substantially perpendicular to said junction line, each of said plurality of parallel elongate channels being adapted to hold a ...

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27-02-2020 дата публикации

FRACTION COLLECTOR CONTROLLER AND PREPARATIVE LIQUID CHROMATOGRAPH

Номер: US20200064315A1
Принадлежит: SHIMADZU CORPORATION

A fraction collector controller includes a threshold storing part, a peak detecting part, a number-of-points-of-data setting part, and a control part. The peak detecting part retrieves, at regular intervals, signals that are from a detector of a liquid chromatograph and are used as points of data, and detects a start point and an end point of a peak by comparing a signal strength and/or an inclination of each of the points of data with the threshold(s). The number-of-points-of-data setting part is configured to set a number of the points of data with which the peak detecting part compares the threshold(s) to detect a start point and an end point of a peak. 13-. (canceled)4. A fraction collector controller for controlling a fraction collector connected to an outlet of a detector of a liquid chromatograph , comprising:a threshold storing part that stores a threshold(s) used for detection of a peak;a peak detecting part configured to retrieve, at regular intervals, signals that are from the detector of the liquid chromatograph and are used as points of data, and to detect a start point and an end point of a peak by comparing a signal strength and/or an inclination of each of the points of data with the threshold(s) stored by the threshold storing part;a number-of-points-of-data setting part configured to set a number of the points of data with which the peak detecting part compares the threshold(s) to detect a start point and an end point of a peak; anda control part configured to control operation of the fraction collector so that components of individual peaks detected by the peak detecting part are collected individually,wherein the peak detecting part is configured to detect a start point or an end point of a peak when, as a condition, a number of successive points of data each of which is detected as the start point or the end point of the peak by comparison of a signal strength and/or an inclination of the point of data with the threshold(s) is equal to or larger ...

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27-02-2020 дата публикации

Variable fluidic restrictor having selective restriction

Номер: US20200064316A1
Принадлежит: Waters Technologies Corp

A variable fluidic restrictor of a liquid chromatography system including a stator body, the stator body include a plurality of fluidic channels located within the stator body, wherein each fluidic channel of the plurality of fluidic channels includes a restrictor element, wherein a flow of a fluid through the variable fluidic restrictor is selectively restricted based on a position of an external element coupled to the stator body is provided. Furthermore, an associated method is also provided.

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16-04-2015 дата публикации

Plasma etching apparatus

Номер: US20150102011A1
Автор: Maxime Varvara
Принадлежит: SPTS Technologies Ltd

A plasma etching apparatus includes first, second and third chambers, and a plasma generation device. An inner cross-sectional area and shape of the second chamber interior substantially corresponds to the upper surface of a substrate, and a substrate support is disposed so that, in use, the substrate is substantially in register with the interior of the second chamber, and the upper surface of the substrate is positioned at a distance of 80 mm or less from the interface between the second and third chambers.

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16-04-2015 дата публикации

Fixed Chamber Separator With Adjustment Withdrawal Member

Номер: US20150104824A1
Принадлежит:

A separation device that can include a separation tube or container that has a wall defining an internal volume into which a material can be placed is disclosed. The material can include a multi-component mixture or solution. A secondary tube or withdrawal cannula can be placed and/or moved within the tube to withdrawal a material form the tube. 1. A system to access at least one component of a multiple component material , comprising:a separation container configured to receive the multiple component material including a sidewall extending from a first end to a second end, the sidewall having an internal surface;a first internal extension wall portion extending towards a central axis of the separation container; anda withdrawal member moveable within the container and configured to interact with the first internal extension wall to assist in removing at least one component of the multiple component material from the separation container;wherein the withdrawal member is moveable between a first position and a second position within the separation container and relative to the first internal extension wall.2. The system of claim 1 , wherein the first internal extension wall portion is angled towards the second end of the separation container.3. The system of claim 1 , wherein the first internal extension wall portion includes a first section and a second section claim 1 , wherein the first section is angled at a first angle towards the second end and the second section is angled at a second angle towards the first end of the container;wherein the withdrawal member is configured to move from the first position to access a component at the first section to the second position to access a second component at the second section.4. The system of claim 3 , wherein the withdrawal member includes:an elongated portion having a withdrawal bore formed therethrough; andan distal portion having a sealing portion at an end of the elongated portion and at least one port formed ...

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19-04-2018 дата публикации

Cooling liquid eluent of a carbon dioxide chromatography system after gas-liquid separation

Номер: US20180106770A1
Принадлежит: Waters Technologies Corp

The present disclosure relates to methodologies, systems and apparatus for cooling a supersaturated or mixed-phase solution to increase the solubility of gases dissolved therein. In a fluid chromatography system, the mobile phase may include a pressurized mixture including a gas, such as CO 2 , and prior to fraction collection and/or detection a portion of the gas is extracted via a gas/liquid separator. Cooling the substantially liquid phase eluent exiting the gas/liquid separator increases the solubility of any remnant gas still dissolved within the eluent. The increased solubility of the remnant gas prevents out gassing, provides more consistent flow of the eluent through the system, and results in more efficient collection and analysis of a desired sample.

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19-04-2018 дата публикации

Fraction Collection System with a Task Scheduler

Номер: US20180107185A1
Автор: THORNTON Kevin
Принадлежит:

A fraction collection system includes one or more chromatography columns. The system also includes one or more fraction collectors for collecting effluent from the columns. The fraction collectors include several racks, each holding a set of collection receptacles. A control system interfaces with the fraction collectors to implement experiments. The control system provides a user interface with which users can schedule runs. The user interface includes a graphical representation of the racks and tubes of the fraction collectors. Users can schedule runs to groups of tubes, and a visual attribute of the representation of the tube in the user interface is updated to indicate that the tubes are assigned to a run. 1. A fraction collection system comprising:one or more chromatography columns;one or more fraction collectors configured to collect effluent from the one or more chromatography columns, each fraction collector including a plurality of racks, each rack holding a plurality of collection receptacles; and a visualization area configured to display a graphical representation of the at least one fraction collector, the graphical representation including a plurality of first geometric shapes corresponding to the plurality of racks, each of the plurality of first geometric shapes encompassing a plurality of second geometric shapes representing the corresponding plurality of collection receptacles; and', 'user controls for scheduling a run to a subset of the collection receptacles, a visual attribute of those of the second geometric shapes that correspond to the subset of the collection receptacles being updated responsive to the scheduling of the run., 'a control system, communicatively coupled to the one or more fraction collectors, the control system configured to provide a run-scheduling interface comprising2. The fraction collection system of claim 1 , wherein a total number of the one or more chromatography columns is greater than a total number of the one or ...

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03-05-2018 дата публикации

A Method and Apparatus for Performing Liquid Chromatography Purification

Номер: US20180120271A1
Принадлежит: GE HEALTHCARE BIO-SCIENCES AB

The present invention relates to a method for performing liquid chromatography purification of one or more target molecules from a sample comprising: providing an eluent flow having one or more target molecules, measuring an output parameter indicative of the content of the one or more target molecules in the eluent flow, storing output parameter data, and dividing the eluent flow into consecutive eluent fractions, dividing the output parameter data into corresponding data fractions, in each data fraction obtaining a value indicative of characteristic behavior of the measured output parameter, identifying trends in the measured output parameter based upon the obtained value in consecutive data fractions, and identifying peak(s) in the measured output parameter correlated to eluent fractions based upon the identified trends, whereby information of identified peak(s) and correlated eluent fraction(s) can be presented and purified sample(s) from the eluent may be collected. 1. A method for performing liquid chromatography purification of one or more target molecules from a sample comprising the steps:a) performing chromatography purification of the sample providing an eluent flow comprising the one or more target molecules,b) measuring an output parameter indicative of the content of the one or more target molecules in the eluent flow, storing output parameter data, andc) dividing the eluent flow into consecutive eluent fractions, and dividing the output parameter data into corresponding data fractions,wherein said method further comprises the steps:d) in each data fraction, obtaining a value indicative of characteristic behavior of the measured output parameter in step b),e) identifying trends in the measured output parameter based upon the obtained value in consecutive data fractions, andf) identifying peak(s) in the measured output parameter correlated to eluent fraction(s) based upon the identified trends.2. The method according to claim 1 , wherein said value ...

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02-05-2019 дата публикации

CHROMATOGRAPHY LAB SYSTEM FOR ANALYZING SAMPLES INCLUDING A COOLING COMPARTMENT WITH AN IDENTIFYING DEVICE THAT IDENTIFIES A FRACTION COLLECTOR DEVICE

Номер: US20190128859A1
Принадлежит: GE HEALTHCARE BIO-SCIENCES AB

A chromatography lab system comprising a cooling compartment arranged to hold both fraction collector devices and sample containers, whereby the cooling compartment comprises an identifying device which is arranged to identify the fraction collector devices such that fractions from the chromatography are collected only in the fraction collector devices. 1. A chromatography laboratory system comprising:a cooling compartment comprising:at least two holder positions configured to hold both fraction collector devices for collecting chromatographically separated fractions and sample containers for providing samples for input into the chromatography laboratory system, andan identifying device comprising a reader configured to read identifying information assigned to the fraction collector devices, to determine that fractions can be supplied to the fraction collection devices, such that said fractions are collected only in the fraction collector devices and not in the sample containers.2. A chromatography laboratory system according to claim 1 , wherein the cooling compartment comprises a plurality of holders in the at least two holder positions claim 1 , wherein the holder positions are configured to hold different types of fraction collector devices or sample containers claim 1 , whereby the identifying device is arranged to identify if a respective holder of the plurality of holders is arranged to hold fraction collector devices.3. A chromatography laboratory system according to claim 2 , wherein the cooling compartment comprises a tray comprising the at least two holder positions.4. A chromatography laboratory system according to claim 3 , wherein each of the at least two holder positions is configured to hold either fraction collector device holders or sample container holders and a type of holder is changeable between different runs of the chromatography lab system.5. A chromatography laboratory system according to claim 4 , wherein at least the holders that are ...

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17-05-2018 дата публикации

PREPARATIVE CHROMATOGRAPH

Номер: US20180136174A1
Принадлежит:

A preparative chromatograph for collecting target components in a sample temporally separated in a column of a chromatograph in respective preparative containers is provided with: a detection unit having a flow cell accommodated in a housing and a detector for detecting a component that passes through the flow cell; a first pipe that connects the column and an inlet end of the flow cell; a flow path switching unit accommodated in the housing and configured to selectively flow the components that passed through the flow cell through a preparative flow path that is a flow path connected to the preparative containers or a waste liquid flow path; and a second pipe accommodated in the housing and connecting an outlet end of the flow cell and the flow path switching unit. 1. A preparative chromatograph for collecting target components in a sample temporally separated in a column of a chromatograph in respective preparative containers , comprising:a) a detection unit having a flow cell accommodated in a housing and a detector for detecting components that pass through the flow cell;b) a first pipe that connects the column and an inlet end of the flow cell;c) a flow path switching unit accommodated in the housing and configured to selectively flow the components that passed through the flow cell to a preparative flow path which is a flow path to be connected to the respective preparative containers or a waste liquid flow path; andd) a second pipe accommodated in the housing, the second pipe connecting an outlet end of the flow cell and the flow path switching unit.2. The preparative chromatograph as recited in claim 1 ,wherein the detection unit is an absorptiometer equipped with an LED light source.3. The preparative chromatograph as recited in claim 1 ,wherein the detection unit is equipped with an optical fiber that transmits irradiation light emitted from a light source arranged outside the housing and irradiated to the flow cell.4. The preparative chromatograph as ...

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08-09-2022 дата публикации

PREPARATIVE LIQUID CHROMATOGRAPH

Номер: US20220283132A1
Принадлежит:

A preparative liquid chromatograph for separating and extracting components in a sample, the preparative liquid chromatograph including a separation channel () through which a mobile phase flows, an injector () that injects the sample into the mobile phase, a separation column () for separating components in the sample injected into the mobile phase, the separation column () being provided downstream of the injector () on the separation channel (), a detector () for detecting peaks of the components separated by the separation column (), a fraction collector () configured to collect an eluate from the separation column () into a plurality of collection containers () at a downstream of the detector () while fractionating the eluate, and a controller () for controlling operation of the fraction collector (), wherein the fraction collector () is provided with peak collection containers () and waste liquid collection containers (), each peak collection container () is used for collecting a peak portion including a collection target peak detected by the detector () in the eluate, and each waste liquid collection container () is used for collecting a waste liquid portion not including the collection target peak in the eluate, and the controller () is configured to collect the peak portion including the collection target peak detected by the detector () in the eluate in the peak collection container (), and to collect at least a part of the waste liquid portion in the waste liquid collection container (). 1. A preparative liquid chromatograph for separating and extracting components in a sample , the preparative liquid chromatograph comprising:a separation channel through which a mobile phase flows;an injector that injects the sample into the mobile phase;a separation column for separating the components in the sample injected into the mobile phase, the separation column being provided downstream of the injector on the separation channel;a detector for detecting peaks of ...

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25-05-2017 дата публикации

CHROMATOGRAPHY LAB SYSTEM

Номер: US20170146498A1
Принадлежит:

A chromatography lab system comprising a cooling compartment arranged to hold both fraction collector devices and sample containers, whereby the cooling compartment comprises an identifying device which is arranged to identify the fraction collector devices such that fractions from the chromatography are collected only in the fraction collector devices. 1. A chromatography lab system comprising a cooling compartment arranged to hold both fraction collector devices and sample containers , whereby the cooling compartment comprises an identifying device which is arranged to identify the fraction collector devices such that fractions from the chromatography are collected only in the fraction collector devices.2. A chromatography lab system according to claim 1 , wherein the cooling compartment comprises at least two holder positions claim 1 , into which holder positions different types of holders for either fraction collector devices or sample containers can be positioned claim 1 , whereby the identifying device is arranged to identify if the holder is arranged to hold fraction collector devices.3. A chromatography lab system according to claim 2 , wherein the cooling compartment comprises a tray comprising the at least two holder positions.4. A chromatography lab system according to claim 3 , wherein each holder position can be used for either fraction collector device holders or sample container holders and this can be changed between different runs of the chromatography system.5. A chromatography lab system according to claim 4 , wherein at least the holders that are arranged to hold fraction collector devices are provided with codes that are read by the identifying device.6. A chromatography lab system according to claim 5 , wherein the cooling compartment comprises at least one port where a sample tube can enter the cooling compartment.7. A method for cooling samples in a chromatography lab system comprising the steps of:placing a sample container in the same ...

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23-05-2019 дата публикации

Method and System for Providing Information from a Fraction Collector in a Liquid Chromatography System

Номер: US20190154641A1
Принадлежит: GE HEALTHCARE BIO-SCIENCES AB

The present invention relates to a method for providing information from a fraction collector in a liquid chromatography system, the system comprising a column, at least one reservoir for containing a fluid, at least one pump connected to said reservoir, a column arranged to receive an input from the reservoir, a measuring device for performing measurements on a fluid output from the column, and a fraction collector for receiving said fluid output in a plurality of receiving vessels, wherein the method comprises—determining at least one parameter of the fraction collector, and—providing information of said parameter on a display in the form of a graphical representation. 1. A method for providing information from a fraction collector in a liquid chromatography system , the system comprising a column , at least one reservoir for containing a fluid , at least one pump connected to said reservoir , a column arranged to receive an input from the reservoir , a measuring device for performing measurements on a fluid output from the column , and a fraction collector for receiving said fluid output in a plurality of receiving vessels , wherein the method comprisesdetermining at least one parameter of the fraction collector, andproviding information relating to said parameter in the form of a graphical representation on a display.2. The method according to claim 1 , wherein the method further comprises receiving information from said measuring device and providing said information together with the information of the parameter on the display.3. The method according to claim 1 , wherein the method further comprises controlling the system in response to said at least one parameter of the fraction collector and/or said information from the measuring device said controlling being provided by user input claim 1 , optionally during chromatographic operation of said system.4. The method according to claim 1 , wherein said at least one parameter is a position of at least one ...

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04-09-2014 дата публикации

FRACTION COLLECTION APPARATUS

Номер: US20140246116A1
Автор: Eriksson Christer
Принадлежит: GE HEALTHCARE BIO-SCIENCES AB

The invention relates to a fraction collector apparatus (′) for positioning at least one fraction collector nozzle (), comprising a frame () arranged for guiding the at least one nozzle () to different positions () in order to collect and dispense fractions () of a substance to or from containers (). At least one track () is arranged in the frame (), and in which at least one track () an endless movable transporting means () is arranged; on which transporting means () the at least one nozzle () is attached; a first actuating means () is connected to said transporting means () for actuating said transporting means () in the track (), so that said at least one nozzle () is movable in different positions () along said track (). The invention also relates to a method of positioning a fraction collector nozzle () by means of such a fraction collection apparatus (′). 1424226810210121241812121042210. A fraction collector apparatus for positioning at least one fraction collector nozzle () , comprising a frame () arranged for guiding the at least one nozzle () to different positions () in order to collect and dispense fractions () of a substance to or from containers () , wherein at least one track () is arranged in the frame () , and in which at least one track () an endless movable transporting means () is arranged; on which transporting means () the at least one nozzle () is attached; a first actuating means () is connected to said transporting means () for actuating said transporting means () in the track () , so that said at least one nozzle () is movable in different positions () along said track ().2241214414424. The apparatus of claim 1 , wherein a nozzle holding means () arranged on said transporting means () and in that a tube () is connected to said at least one nozzle () claim 1 , so that the tube () and the nozzle () are detachable from the nozzle holding means ().312. The apparatus of claim 1 , wherein said endless transporting means () is a chain claim 1 , ...

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29-09-2022 дата публикации

SYSTEM AND METHOD FOR ISOLATION OF INTACT EXTRACELLULAR VESICLES WITH NEAR-SINGLE-VESICLE RESOLUTION COUPLED WITH ON-LINE CHARACTERIZATION

Номер: US20220305405A1

A method and system are disclosed for isolating intact acellular particles using size exclusion and for obtaining size and concentration of such isolated particles. In one embodiment, the disclosure is directed to use of Particle Purification Liquid Chromatography (PPLC), a high-resolution chromatographic size-guided turbidimetry-enabled system for dye-free isolation, on-line characterization, and retrieval of intact acellular particles, including extracellular vesicles (EVs) and membraneless condensate particles (MCs) from various biofluids. 1. A method for isolating intact acellular particles comprising:(i) providing a biofluid sample containing intact acellular particles of different sizes;(ii) separating the biofluid sample using a size exclusion gradient into subpopulations of intact acellular particles, each respective subpopulation individually comprising a different size range of intact acellular particles; and(iii) isolating a respective subpopulation.2. The method of wherein the biofluid sample comprises one or more of the following: a biological fluid claim 1 , a body fluid claim 1 , a culture fluid obtained from a human cell claim 1 , a culture fluid obtained from a bacterial cell claim 1 , a culture fluid obtained from a fungus cell.3. The method of further comprising:(iv) analyzing the respective subpopulation to determine size of the intact acellular particles therein, the concentration of the intact acellular particles therein, or both.4. The method of wherein the intact acellular particles comprise extracellular vesicles claim 1 , membraneless condensate particles claim 1 , or both.5. The method of wherein the separating step of (ii) comprises contacting the biofluid sample with size exclusion beads to separate the intact acellular particles into the subpopulations.6. The method of wherein the size exclusion beads comprise different pore sizes and are configured to form the gradient going from largest pore size to smallest pore size and wherein the ...

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29-09-2022 дата публикации

AUTOMATED SEMI-PREPARATIVE GRADIENT RECYCLING LIQUID CHROMATOGRAPHY

Номер: US20220308020A1
Автор: GRITTI Fabrice
Принадлежит: WATERS TECHNOLOGIES CORPORATION

The disclosure relates to a gradient twin column recycling chromatography method that is used to separate a mixture containing closely eluting compounds. In one embodiment, a sample includes a primary organic compound and one or more impurities that closely elute with the primary organic compound. A gradient mobile phase is initially used to remove unwanted early eluting and late eluting impurities from the sample. After the gradient removal of some of the impurities is complete, the remaining mixture of the primary organic compound and the closely eluting impurities are separated using recycle chromatography methodology with an isocratic mobile phase. 1. A method of performing recycling chromatography comprising: a first chromatographic column and a second chromatographic column coupled to each other in series; and', 'a fraction collector coupled to the first chromatographic column and the second chromatographic column;', 'passing the sample through the first chromatographic column using a gradient mobile phase stream, wherein during passage of the sample through the first chromatographic column one or more of the impurities are transferred to the fraction collector and the organic compound and as least one of the one or more impurities are transferred to the second chromatographic column as an analyte band;', 'passing the analyte band through the second chromatographic column using an isocratic mobile phase stream;', 'recycling the analyte band from the second chromatographic column to the first chromatographic column and from the first chromatographic column to the second chromatographic column using the isocratic mobile phase stream until a baseline resolution of the organic compound and one or more of the impurities is achieved;', 'passing the organic compound to the fraction collector., 'injecting a sample into a mobile phase flow stream of a chromatography system to create a combined flow stream, the sample comprising an organic compound and one or more ...

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25-09-2014 дата публикации

APPARATUS, SYSTEM AND METHOD FOR MASS DIRECTED CHROMATOGRAPHY

Номер: US20140284279A1
Принадлежит: Biotage AB

The present invention provides an apparatus that can be used to connect a flash chromatography instrument to a fraction collector and a mass detector to perform mass-directed flash chromatography. 1. Apparatus comprising a first inlet for receiving a first fluid stream;', 'a second inlet for receiving a second fluid stream;', 'a by-passable delay loop;', 'an outlet; and', 'an active splitter between said first inlet and said by-passable delay loop,, 'a first fluid path comprising'}wherein the active splitter is configured to move a portion of a fluid stream in said first fluid path to a fluid stream in a second fluid path,said second fluid path including an inlet upstream of the active splitter and an outlet downstream of the active splitter.2. Apparatus according to claim 1 , wherein said first fluid path includes a first valve between the first inlet port of the first fluid path and the active splitter wherein said first valve in one position directs the fluid flow directly to the outlet port of the first fluid path and in another position directs the fluid flow to the active splitter.3. Apparatus according claim 1 , wherein said first fluid path comprises a second valve between the active splitter and the by-passable delay loop claim 1 , wherein said second valve in one position directs the fluid flow to the outlet port of the first fluid path and in another position directs the fluid flow to the delay loop.4. Apparatus according to claim 1 , wherein the second inlet is configured for direct manual injection of a fluid sample.5. Apparatus according to claim 1 , further comprising in said second fluid path a pump upstream of the active splitter and configured to pump solvent from a solvent reservoir into said second fluid path claim 1 , and optionally a pressure sensor configured to measure the pressure in the second fluid path.6. Apparatus according to claim 1 , further comprising in said second fluid path a filter downstream of said active splitter.7. Apparatus ...

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12-07-2018 дата публикации

Preparative liquid chromatographic apparatus

Номер: US20180196020A1
Автор: Kihachiro Okura
Принадлежит: Yamazen Corp

An object of the present disclosure is to reduce labor for dispensing by a preparative liquid chromatographic apparatus by performing qualitative analysis simultaneously with dispensing and omitting labor for qualitative analysis after dispensing. A preparative liquid chromatographic apparatus comprising: a column (A) for separating components in a sample; a dispensing unit (B) for dispensing an eluate from the column; a detector (C) for the eluate; an analysis unit (D) for the eluate; a display unit (E) for displaying an analysis result; a data storage unit (G) for storing data; and an arithmetic control unit (F) for controlling the display unit (E) and the data storage unit (G), wherein the analysis unit (D) has at least one qualitative analysis unit for continuously and qualitatively analyzing the eluate, and the data storage unit (G) stores at least a measurement result of the detector (C), qualitative analysis data of an effluent analyzed by the analysis unit (D), and an acquisition position of each fraction dispensed by the dispensing unit (B), wherein the display unit (E) simultaneously displays a chromatogram acquired by the detector (C) and the acquisition position of the dispensing unit (B) and displays a correspondence relationship between the each fraction and the chromatogram, and wherein with respect to a specific dispensed sample designated in accordance with an observer's desire by using the correspondence relationship between the each fraction and the chromatogram shown in the display unit (E), the qualitative analysis data selected from the data storage unit (G) is displayed on the display unit (E) by using the arithmetic control unit (F).

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03-09-2015 дата публикации

METHOD OF FRACTION COLLECTION FOR A LIQUID CHROMATOGRAPHY SYSTEM

Номер: US20150246296A1
Принадлежит:

Described are a fraction collector and a method of fraction collection for a liquid chromatography system. The method includes diverting a liquid chromatography system flow from a waste channel to a collection tube at a start of a fraction collection window and collecting the system flow dispensed from the collection tube during the fraction collection window. At the end of the window, the system flow is diverted to the waste channel and a flow of a wash solvent is provided to the collection tube to dispense liquid remaining in the collection tube at the end of the window from the collection tube. The method can increase the amount of the collected fraction and can reduce or eliminate cross-contamination of a subsequently collected fraction. The method is useful for analytical scale applications where the collected fractions may have volumes defined by a limited number of drops dispensed from the collection tube. 1. A fraction collector for a liquid chromatography system , the fraction collector comprising:a valve having a first port to receive a liquid chromatography system flow, a second port in fluidic communication with a waste channel, a third port and a fourth port, the valve having a first state in which the first port is in fluidic communication with the third port and the second port is in fluidic communication with the fourth port, the valve having a second state in which the first port is in fluidic communication with the second port and the third port is in fluidic communication with the fourth port, the valve having a control port to receive a valve control signal to control the valve to be in one of the first or second states;a wash solvent source in fluidic communication with the fourth port and configured to provide a flow of a wash solvent, the wash solvent source having a control port to receive a wash control signal to control the flow of the wash solvent; anda collection tube in fluidic communication with the third port to receive the liquid ...

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25-07-2019 дата публикации

Method and Apparatus for Chromatograph Nano-Flow Fractionator

Номер: US20190227040A1
Принадлежит: Thermo Finnigan LLC

A nano-flow fractionator apparatus, comprises: one or more sources of mobile phase solvent; a source of auxiliary solvent; a sample injection valve; a chromatographic column having an inner diameter of less than or equal to 75 micro-meters, a column inlet end and a column outlet end; a solvent fraction delivery line comprising: an inlet end that is configured to receive eluate that is emitted from the column outlet end and an outlet end that is configured to dispense the eluate to each of a plurality of sample fraction containers; a fluid junction configured to receive the eluate that is emitted from the column outlet end and to receive a flow of the auxiliary solvent that is delivered from the source of auxiliary solvent and to deliver the eluate and the flow of auxiliary solvent to the solvent fraction delivery line.

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30-07-2020 дата публикации

FRACTION COLLECTOR CONTROL DEVICE AND PREPARATIVE LIQUID CHROMATOGRAPH

Номер: US20200240966A1
Принадлежит:

A fraction collector control device includes a peak designation part that displays a chromatogram for setting and requires a user to select at least one peak in the chromatogram for setting, a parameter extraction part that extracts, as a parameter, a signal level and/or a slope at a start point and an end point of each peak designated by a user, and a threshold candidate generation part that generates, based on the parameter extracted by the parameter extraction part, a threshold candidate usable as a common threshold for detecting start points of all peaks designated by a user and a common threshold for detecting end points of all peaks designated by a user. 1. A fraction collector control device for controlling operation of a fraction collector ,the fraction collector being a device for fractionating and collecting components separated in an analysis column of a liquid chromatograph based on a signal obtained by a detector of the liquid chromatograph,the fraction collector control device comprising:a peak designation part configured to display a chromatogram based on analysis data of a liquid chromatograph acquired in advance as a chromatogram for setting, and to require a user to select at least one peak in the chromatogram for setting;a parameter extraction part configured to extract, as a parameter, a signal level and/or a slope at a start point and an end point of each peak designated by the user;a threshold candidate generation part configured to generate, based on the parameter extracted by the parameter extraction part, a threshold candidate usable as a common threshold for detecting start points of all peaks designated by the user and a common threshold for detecting end points of all peaks designated by the user; anda control part configured to control the fraction collector and to detect peaks by using a threshold determined based on the threshold candidate generated by the threshold candidate generation part so that components of the peaks are ...

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18-12-2014 дата публикации

Particulate Material Sample Divider

Номер: US20140366652A1
Принадлежит:

A particulate material sample divider includes a separation cone extending downwardly and radially outwardly from a central apex to an annular bottom edge with separator baffles supported on an outer surface of the separation cone at circumferentially spaced apart positions so as to define alternate first and second channels extends downwardly and radially outwardly between respective adjacent pairs of the baffles. A hopper supported above the separation cone discharges the sample over the cone for separation into the first and second channels. Each second channel only communicates with a second collection area to an outer side of a divider wall between the bottom edge of the cone. Each first channel includes an aperture in the separation cone such that each first channel only communicates through the aperture to a first collection area at an inner side of the divider wall. 1. A sample divider for dividing particulate material into two portions , the divider comprising:a separation cone extending downwardly and radially outwardly from a central apex to an annular bottom edge;a hopper supported above the separation cone so as to taper downwardly and inwardly towards a discharge opening at a bottom end of the hopper which is centrally located above the central apex of the separation cone;a gate member supported at the bottom end of the hopper so as to be operable relative to the discharge opening between an open position and a closed position;a plurality of separator baffles supported on an outer surface of the separation cone at circumferentially spaced apart positions so as to define a plurality of first channels and a plurality of second channels in which each of the first and second channels extends downwardly and radially outwardly between an adjacent pair of the separator baffles;an annular divider wall extending downwardly from the bottom edge of the separation cone so as to define a first collection area adjacent an inner side of the divider wall and a second ...

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28-09-2017 дата публикации

PORTABLE EFFICIENT MAGNETIC SOLID PHASE EXTRACTION DEVICE AND EXTRACTION METHOD THEREOF

Номер: US20170276576A1
Принадлежит:

A device comprises a contact reaction chamber, a circulating water inlet, a clear water basin, a circulating pump, a circulating water outlet, a solid phase extractant collecting tank, a magnetic holder, an electromagnet, a solid-liquid separation area, a drain valve, a wall sprinkling water inlet, and a wall sprinkling pipe, wherein, the contact reaction chamber is in a conical shape, and utilizes hydraulic power to perform stir to ensure no dead corner exists during contact stir; the obconical solid-liquid separation area increases the action area between a magnetic solid phase extractant and the electromagnet; the solid phase extractant collecting tank is in a downwards protruding dish shape to prevent the solid phase extractant from losing. 112341512526789101112131141214215161718. A portable efficient magnetic solid phase extraction device , characterized in that: the device mainly comprises a contact reaction chamber () , a circulating water inlet () , a clear water basin () , a three-way valve c() , a water delivery pipe a-(-) , a water delivery pipe a-(-) , a circulating pump () , a circulating water outlet () , a solid phase extractant collecting tank () , a magnetic holder () , an electromagnet () , a solid-liquid separation area () , a water outlet () , a three-way valve d() , a water delivery pipe b-(-) , a water delivery pipe b-(-) , a drain pipe () , a drain valve () , a wall sprinkling water inlet () , and a wall sprinkling pipe () ,{'b': 2', '7', '1', '2', '4', '1', '5', '1', '7', '4', '3', '7', '4', '1', '11', '12', '8', '10', '9', '11, 'wherein, the circulating water inlet () and the circulating water outlet () are respectively located at the upper part and lower part of the contact reaction chamber (); the circulating water inlet () is connected to the three-way valve c() via the water delivery pipe a-(-); the circulating water outlet () is connected to the three-way valve c() via a pipe; the clear water basin () is connected to the pipe between ...

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06-10-2016 дата публикации

FRACTION COLLECTOR

Номер: US20160288016A1
Принадлежит: SHIMADZU CORPORATION

A moving section that moves in the horizontal plane direction at above a collection container section where collection containers are set is provided with a nozzle holding section for holding a nozzle, and a waste port holding section for holding a waste port. The moving section is capable of moving the nozzle holding section or the waste port holding section. Accordingly, one of a state where the waste port is at a position immediately below the tip of the nozzle and a state where the waste port is not at the position immediately below the tip of the nozzle may be achieved. 1. A fraction collector comprising:a collection container section for setting a collection container whose top is open so as to collect a sample flowing out of a detector of a liquid chromatograph;a moving section for moving in a horizontal plane direction at above the collection container section;a nozzle that is connected to a channel through which a liquid flowing out of the detector flows;a nozzle holding section, provided at the moving section, for holding the nozzle in such a way that a tip of the nozzle faces downward;a waste port, whose top is open, for leading a waste liquid to a drain;a waste port holding section, provided at the moving section, for holding the waste port; anda drive mechanism for moving the nozzle holding section or the waste port holding section so as to selectively achieve a state where the waste port is at a position immediately below the tip of the nozzle or a state where the waste port is not at the position immediately below the tip of the nozzle.2. The fraction collector according to claim 1 , further comprising:a collection operation section for performing a collection operation of achieving, when a start point of a peak originating from a sample component is detected based on a detection signal of the detector, the state where the waste port is not present at the position immediately below the nozzle, before a liquid at a part corresponding to the peak ...

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10-09-2020 дата публикации

Method for Operating a Fractionation Collector During Chromatography

Номер: US20200284769A1
Автор: Bozic Alexander
Принадлежит:

The present invention describes a method of operating a fractionation collector in chromatography, and a chromatograph system for carrying out the method, wherein a solvent composition is pumped into a chromatography column, which contains at least a portion of a first solvent that is liquid under normal conditions and contains a portion of a second solvent that is gaseous at normal conditions, and the composition flowing out of the chromatography column is at least partially introduced into a detector, wherein a composition containing the first solvent, after leaving the chromatography column, is introduced into a collection vessel of the fraction collector in dependence of the detector signal, and the amount of liquid that is introduced into a collecting vessel of the fraction collector is selected in dependence of the portion of said first solvent. 1. A method of operating a fractionation collector for chromatography , wherein a solvent composition is pumped into a chromatography column that contains at least a portion of a first solvent that is liquid under normal conditions , and contains a portion of a second solvent that is gaseous under normal conditions , and the composition flowing out of said chromatography column is at least partially introduced into a detector , wherein a composition containing said first solvent , after leaving the chromatography column , is introduced into a collecting vessel of the fraction collector in dependence of the detector signal , and the amount of liquid that is introduced into a collecting vessel of said fraction collector is selected in dependence of the portion of said first solvent.2. The method according to claim 1 , wherein the solvent composition pumped into a chromatography column is changed in the course of the chromatography.3. The method according to claim 1 , wherein the portion of the first solvent in the solvent composition is determined via a time of the beginning of the fraction collection claim 1 , and a ...

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08-11-2018 дата публикации

PREPARATIVE SEPARATION CHROMATOGRAPH SYSTEM

Номер: US20180321200A1
Принадлежит: SHIMADZU CORPORATION

A preparative separation chromatograph system having a column for temporally separating components in a sample and for discharging an eluate fluid with the components, a detector for obtaining an absorbance spectrum of the eluate fluid, and a fraction collector for continuously creating a chromatogram. The system further includes: a peak section determiner; a differential value determiner for calculating a differential spectrum value and for determining whether or not the absolute value of the differential spectrum value is equal to or less than a predetermined value; and a fraction collector controller for controlling the fraction collector so as to fractionate the eluate fluid during a period of time for which it is determined that the chromatogram peak of the target component is present and for which it is also determined the absolute value of the differential spectrum value is equal to or less than the predetermined value. 1. A preparative separation chromatograph system having a column for temporally separating components in a sample and for discharging an eluate fluid with the components , a detector for obtaining an absorbance spectrum A(λ) of the eluate fluid , and a fraction collector for continuously creating a chromatogram S(t) in real time based on the absorbance spectrum A(λ) and for fractionating the eluate fluid based on the chromatogram S(t) to separately collect a target component , the system further comprising:a) a peak section determiner for determining whether or not a chromatogram peak of the target component is present based on the chromatogram S(t);b) a differential value calculator for calculating a differential spectrum value A′(λ0)=d(A(λ))/dλ|λ=λ0 which is a value of a wavelength differential d(A(λ))/dλ of the absorbance spectrum A(λ) at a known wavelength λ0 at which an absorbance of the target component has a local maximum or local minimum value; andc) a fraction collector controller for controlling the fraction collector so as to ...

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24-11-2016 дата публикации

Device and Method for Clinical Data Sampling and Specimen Banking

Номер: US20160341754A1
Автор: ROSENBLOOM Alan

A system and method are described that allow the autonomous collection of relevant data and samples from a patient during a clinical trial or during routine care. Sampling is accomplished by drawing multiple samples into tubing, such as microfluidic tubing, and using a pump to move the samples through the tubing. A spacer fluid is provided to separate each sample and to prevent contamination between each. A microcontroller is used to control the operation of the pump and to gather data about the patient from the electronic medical record or other alternative inputs, and the sampling, including data from onboard sensors. 1. A patient data and sample collection and banking system comprising:a tube capable of transporting a sample;a first pump coupled to the tube, wherein the first pump moves the sample through the tube;a spacer fluid;a second pump in fluid communication with the spacer fluid and connected to the tube, wherein the second pump is capable of injecting the spacer fluid into the tube;a sensor capable of differentiating between the sample and the spacer fluid contained within the tube, wherein the sensor generates a data signal;a microcontroller electrically connected to each of the sensor, the first pump, and the second pump, wherein the microcontroller sends control signals to the first pump and the second pump, causing the second pump to interpose the spacer fluid between the sample and an adjacent subsequent sample; anda communications interface connecting the microcontroller to a database, wherein the microcontroller is capable of receiving and transmitting data through the communications interface.2. The system of claim 1 , further comprising:a storage vessel, wherein a portion of the tube is contained within an interior volume of the storage vessel; anda cooling device that cools the interior volume of the storage vessel.3. The system of claim 2 , wherein the cooling device is a thermoelectric cooler.4. The system of claim 1 , wherein the database is ...

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06-12-2018 дата публикации

Subsurface Environment Sampler

Номер: US20180348093A1
Принадлежит:

A Sampler and process for collecting, growing, inoculating and evaluating microbes in-situ. The Sampler may be loaded with an active or inert media to assist with the collection of microbes. It is closed and lowered to a desired depth. Sampler is opened to initiate sampling. Materials are added to the sampler to stimulate growth or change the environment. To collect and grow in situ microbes, the sampler is left open for a period of time, a trigger closes and seals the sampler capturing contents specific to that location. The sampler is lifted preserving the in-situ conditions from the collection location. The contents of the sampler can be interrogated through sealed ports at the field site or at a remote location. The sampler can also be utilized as a biologic reactor allowing researchers to connect laboratory equipment to analyze, modify, or cultivate the collected sample. 1. A Subsurface Environment Sampler comprising:a first housing including an actuator with a source connected to an end of the first housing to trigger the actuator;a second housing mated with the first housing with a removable cap placed on the end of the second housing;at least a collection chamber placed in the second housing;at least two slots formed in the second housing surrounding an entire outer perimeter of the second housing exposing the chamber to the environment;the actuator capable of closing the Sampler by exerting force on the chamber, thereby creating a seal between the chamber and the second housing to maintain in-situ condition at depths greater than 250 feet.2. A Subsurface Environment Sampler of claim 1 , with the chamber further comprising a third housing claim 1 , and a screened microbial collection module placed in the third housing with caps formed on each end of the third housing.3. A Subsurface Environment Sampler of claim 2 , with each of the caps of the chamber including compressible material to seal the chamber.4. A Subsurface Environment Sampler of claim 3 , with ...

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20-12-2018 дата публикации

APPARATUS FOR ASSAY, SYNTHESIS AND STORAGE, AND METHODS OF MANUFACTURE, USE, AND MANIPULATION THEREOF

Номер: US20180361345A1
Принадлежит:

The invention features methods of making devices, or “platens”, having a high-density array of through-holes, as well as methods of cleaning and refurbishing the surfaces of the platens. The invention further features methods of making high-density arrays of chemical, biochemical, and biological compounds, having many advantages over conventional, lower-density arrays. The invention includes methods by which many physical, chemical or biological transformations can be implemented in serial or in parallel within each addressable through-hole of the devices. Additionally, the invention includes methods of analyzing the contents of the array, including assaying of physical properties of the samples. 150-. (canceled)51. A device for filling through-holes in a platen , the device comprising:a platen comprising a two-dimensional array of through-holes, each of the through-holes configured to receive at least one reagent;a nozzle having an aperture of a suitable size to inject a sample into a plurality of the array of through-holes; anda valve configured to control a flow of a sample through the nozzle;wherein the nozzle is configured to move in at least two dimensions to predetermined positions over respective ones of the plurality of through-holes.52. The device of claim 51 , wherein the nozzle is positioned so as to contact the platen.53. (canceled)54. The device of claim 51 , further comprising a computer that controls the valve and controls the predetermined positions of the nozzle over the plurality of through-holes.5563-. (canceled)64. A method of storing a plurality of samples in an assay-ready claim 51 , high-density format claim 51 , the method comprising:a) providing a platen having a plurality of through-holes;b) loading the through-holes with said samples dissolved in a mixture comprising two solvents, a first solvent having a low vapor pressure and a second solvent having a higher vapor pressure; andc) evaporating the second solvent to result in a plurality ...

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15-09-1981 дата публикации

Method of automatic control of invert sugar fractionating

Номер: SU865133A3

As disclosed herein, the angle of optical rotation, concentration, flow rate and temperature of the components such as, for example, glucose and fructose in an aqueous solution emerging from a fractionating process are continuously measured and signals corresponding to the measurements are fed to a computer. The computer calculates the instantaneous and/or average purity and/or the expected purity of the components and, when predetermined purity values are reached, the computer controls the distribution of the various fractions in accordance with a preset program.

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13-01-1982 дата публикации

Control circuit for micro flow rate

Номер: JPS576358A
Автор: Kenichi Kanehira
Принадлежит: Tokyo Rikakikai Co Ltd

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01-02-1994 дата публикации

Apparatus for coupled liquid chromatography and nuclear magnetic resonance spectroscopy measurements

Номер: US5283036A
Принадлежит: Bruker Analytische Messtechnik GmbH

Apparatus is provided for coupled liquid chromatography and nuclear magnetic resonance (NMR) spectroscopy measurements. The apparatus includes a liquid chromatograph, an intermediate storage device for intermediately storing of components of a probe eluent and an NMR spectrometer. Selected intermediately stored components are fed to an NMR measurement unit. The intermediate storing device includes a number of capillary tubes, which are switchable by an automatically controlled valve arrangement for selectively receiving and delivering desired eluent components.

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18-05-1984 дата публикации

Patent FR2522154B1

Номер: FR2522154B1
Автор: [UNK]
Принадлежит: HORIBA JOBIN YVON SAS

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10-02-2022 дата публикации

Preparative chromatograph

Номер: JP7006811B2
Автор: 隆之 入来
Принадлежит: Shimadzu Corp

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25-09-2018 дата публикации

Preparative separation chromatograph

Номер: CN106053616B
Автор: 入来隆之, 大古场努
Принадлежит: Shimadzu Corp

提供一种制备分离色谱仪,包括:具有检测器(15)的色谱仪10;馏分收集器(20);控制器(34),用于参考当来自检测器(15)的输出信号的变化率超过正参考值时的点,命令馏分收集器发起收集操作,并且参考变化率的绝对值在变化率转向负之后变得比负参考值的绝对值小的点,中止操作;存储部(31),用于存储采样率信息,采样率信息将输出信号的值与控制器确定变化率的时间间隔关联;以及采样率确定器(33),用于基于采样率信息和输出信号的实际值,确定用于计算变化率的时间间隔。

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30-07-2003 дата публикации

Apparatus for assay, synthesis and storage, and methods of manufacture, use, and manipulation thereof

Номер: EP1330306A2
Принадлежит: Biotrove Inc

The invention features methods of making devices, or 'platens' having a high-density array of through-holes, as well as methods of cleaning and refurbishing the surfaces of the platens. The invention further features methods of making high-density arrays of chemical, biochemical, and biological compounds, having many advantages over conventional, lower-density arrays. The invention includes methods by which many physical, chemical or biological transformations can be implemented in serial or in parallel within each addressable through-hole of the devices. Additionally, the invention includes methods of analizying the contents of the array, including assaying of physical properties of the samples. In various embodiments, the reagents can be contained within the through-holes by capillary action, attached to the walls of the through-hole. The porous material can be, for example, a gel, a bead, sintered glass, or particulate matter, or can be the inner wall of a ghrough-hole that has been chemically etched. In particular embodiments, the arrays can include invidual molecules, complexes of molecules, viruses, cells, groups of cells, pieces of tissue, or small particles or beads. The members of the arrays can aslo, for example, function as transducers that report the presence of an analyte (e.g., by providing an easily detected signal), or they can function as selective binding agents for the retention of analytes of interest. Using these methods, arrays corresponding to a large plurality of human genes (e.g., using nucleic acid probes) can also be prepared.

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01-05-2018 дата публикации

A kind of Fishery Ecology cultivation water intellectual monitoring equipment

Номер: CN107976339A
Автор: 吴传江
Принадлежит: Individual

本发明涉及一种渔业生态养殖水质智能监测装备,包括移动装置,移动装置的左侧安装有取样装置,移动装置包括移动底板,移动底板的中部设置有移动升降孔,移动升降孔内设置有移动固定机构,移动底板的下端设置有两个移动驱动机构,两个移动驱动机构对称位于移动底板的左右两侧,移动底板的下端安装有漂浮气垫。本发明可以解决现有水质研究取样过程中存在的需要人工驾驶水上漂浮设备在水面上进行移动作业,需要人工对研究的水域进行取样处理等难题,可以实现生态养殖水质自动化移动抽样的功能,无需人工操作,不受天气影响,且具有稳定性好、灵活性高,操作简单、劳动强度小与工作效率高等优点。

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13-07-2011 дата публикации

Chromatograph mass spectrometer

Номер: JP4725082B2
Автор: 佳克 梅村
Принадлежит: Shimadzu Corp

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16-03-1999 дата публикации

Liquid chromatography

Номер: JPH1172489A
Принадлежит: HITACHI LTD

(57)【要約】 【課題】迅速な同定を行い、同定能力を向上させ、同定 が確実に行われたことを確認容易な液体クロマトグラ フ、さらに実試料中から目的成分のみを確実に分取可能 な液体クロマトグラフを提供すること。 【解決手段】ポンプ,試料注入装置,カラム,フォトダ イオードアレイ検出器,既知成分のスペクトルを登録し たスペクトルライブラリを持つデータ処理装置により構 成されるクロマトグラフにおいて、あらかじめ前記スペ クトルライブラリより選択されたスペクトルと、実試料 における各ピークのスペクトルとを比較する。 【効果】目的成分の同定に要するスペクトル比較回数が 減少し、さらに分析中でも同定可能であることから迅速 な同定を行うことができる。

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04-10-2011 дата публикации

Systems for filling a sample array by droplet dragging

Номер: US8029745B2
Принадлежит: Massachusetts Institute of Technology

Systems for filling sample array by droplet dragging are provided. One aspect of the invention provides an array filling system for filling a platen having a platen surface and an array of receptacles, the receptacles having an internal surface and the receptacles separated by the platen surface, the system comprising: a liquid transfer device capable of holding liquid; and a controller configured to position the liquid transfer device in proximity to the platen surface and to move the liquid transfer device across the surface and over the receptacles to be filled so as to cause sequential communication of liquid in the liquid transfer device with the interior surface of each receptacle.

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07-09-2018 дата публикации

A kind of micro- plastic multi-cavity room sampler of surface water

Номер: CN108507837A
Автор: 刘志东

本发明公开了一种表层水体微塑料多腔室取样装置,包括圆柱型网具框架、若干滤网结构、贯穿装置内部的连杆、若干与连杆相配合的限位装置、漏盒、以及固设于网具框架两侧的浮漂组成,所述装置内的若干滤网及滤网结构从上至下网孔尺寸大小依次减小,与现有技术相比,现有的表层水体微塑料采集装置仅通过一次滤网过滤筛选水体中的微塑料垃圾,无法将其分隔开,本发明提供的装置能对水体表面的不同体积微塑料、有机污染球体垃圾进行筛查,结构简单设计合理。

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02-01-1975 дата публикации

Dosing device

Номер: DE2233913B2
Принадлежит: Instrumentation Laboratory Co

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07-03-2019 дата публикации

Method for operating a fractionation collector in a chromatography

Номер: DE102017120421A1
Автор: Anmelder Gleich
Принадлежит: Alexander BOZIC

Die vorliegende Erfindung beschreibt ein Verfahren zum Betreiben eines Fraktionierungssammlers bei einer Chromatographie, wobei eine Lösungsmittelzusammensetzung in eine Chromatographiesäule gepumpt wird, die zumindest einen Anteil an einem ersten Lösemittel enthält, das bei Normalbedingungen flüssig ist, und einen Anteil an einem zweiten Lösemittel enthält, das bei Normalbedingungen gasförmig ist, und die aus der Chromatographiesäule fließende Zusammensetzung zumindest teilweise in einen Detektor eingeleitet wird, wobei eine das erste Lösungsmittel enthaltende Zusammensetzung nach dem Verlassen der Chromatographiesäule in Abhängigkeit des Detektorsignals in ein Sammelgefäß des Fraktionssammlers eingeleitet wird und die Menge an Flüssigkeit, die in ein Sammelgefäß des Fraktionssammlers eingeleitet wird, in Abhängigkeit des Anteils an dem ersten Lösungsmittel gewählt wird.Weiterhin beschreibt die vorliegende Erfindung eine Chromatographieanlage zur Durchführung des vorliegenden Verfahrens. The present invention describes a method of operating a fractionation collector in a chromatography wherein a solvent composition is pumped into a chromatography column containing at least a portion of a first solvent which is liquid under normal conditions and containing a proportion of a second solvent which is incorporated herein by reference Normal conditions is gaseous, and the composition flowing from the chromatography column is at least partially introduced into a detector, wherein a composition containing the first solvent is introduced after leaving the chromatography column in response to the detector signal in a collecting vessel of the fraction collector and the amount of liquid in a collecting vessel of the fraction collector is introduced, depending on the proportion of the first solvent is selected.Further, the present invention describes a chromatographic system for carrying out the present method.

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23-06-1978 дата публикации

DIVIDER DEVICE FOR LIQUID SAMPLES INTO ALIQUOT PORTIONS

Номер: FR2372578A7
Автор: [UNK]
Принадлежит: Mettler Instrumente AG

Dispositif diviseur d'échantillons liquides. Il comprend un rotor central 36 comportant une cavité 38 dans laquelle se déverse l'échantillon devant être divisé et qui comporte au moins un trou radial transversal 50, 50', 50'' dans sa cloison, le rotor étant entouré de plusieurs chambres fixes 14 dont les cloisons 26 qui les séparent sont à arête vive au moins dans la zone de sortie des trous transversaux, certaines au moins de ces chambres étant équipées d'une tubulure d'écoulement 18. Application à tous les appareils diviseurs d'échantillons et très avantageusement à ceux qui sont équipés d'un rotor de séparateur centrifuge. Liquid sample divider device. It comprises a central rotor 36 comprising a cavity 38 into which the sample to be divided flows and which comprises at least one transverse radial hole 50, 50 ', 50' 'in its partition, the rotor being surrounded by several fixed chambers 14 in which the partitions 26 which separate them have a sharp edge at least in the area of exit from the transverse holes, at least some of these chambers being equipped with a flow pipe 18. Application to all sample dividing devices and very advantageously to those which are equipped with a rotor of a centrifugal separator.

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11-02-2011 дата публикации

DEVICE FOR TRANSFERRING A MEDIUM

Номер: FR2940439B1
Автор: Stephane Olivier
Принадлежит: Millipore Corp

Le dispositif pour le transfert d'un milieu comprend un barillet (2) et au moins un élément de transfert (3) dudit milieu, ledit élément de transfert (3) comportant un conduit (45) de transfert dudit milieu muni à une extrémité d'une aiguille (31), un septum (32), et un organe de manoeuvre (33) de ladite aiguille (31), ledit élément de transfert (3) comportant également des moyens de verrouillage (61, 65) adaptés à coopérer avec des moyens de verrouillage complémentaires (15) dudit barillet (2) pour verrouiller ladite aiguille (31) dans une position d'attente, lesdits moyens de verrouillage (61, 62, 65) appartenant audit organe de manoeuvre (33) et coopérant avec lesdits moyens de verrouillage complémentaires (15) à un endroit du barillet (2) distinct de l'endroit par lequel débouche de la cavité (20), du côté opposé à ladite aiguille (31), ledit conduit (45). The device for transferring a medium comprises a barrel (2) and at least one transfer element (3) of said medium, said transfer element (3) comprising a duct (45) for transferring said medium provided at one end with a needle (31), a septum (32), and an operating member (33) of said needle (31), said transfer element (3) also comprising locking means (61, 65) adapted to cooperate with complementary locking means (15) of said barrel (2) for locking said needle (31) in a standby position, said locking means (61, 62, 65) belonging to said operating member (33) and cooperating with said complementary locking means (15) at a location of the barrel (2) distinct from the location through which the cavity (20) opens, on the side opposite to said needle (31), said duct (45).

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27-05-2005 дата публикации

METHOD AND DEVICE FOR ANALYZING A BLOOD SAMPLE

Номер: FR2841653B1
Автор: Comte Roger Le
Принадлежит: ABX SA

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25-06-2010 дата публикации

DEVICE FOR TRANSFERRING A MEDIUM

Номер: FR2940439A1
Автор: Stephane Olivier
Принадлежит: Millipore Corp

Le dispositif pour le transfert d'un milieu comprend un barillet (2) et au moins un élément de transfert (3) dudit milieu, ledit élément de transfert (3) comportant un conduit (45) de transfert dudit milieu muni à une extrémité d'une aiguille (31), un septum (32), et un organe de manoeuvre (33) de ladite aiguille (31), ledit élément de transfert (3) comportant également des moyens de verrouillage (61, 65) adaptés à coopérer avec des moyens de verrouillage complémentaires (15) dudit barillet (2) pour verrouiller ladite aiguille (31) dans une position d'attente, lesdits moyens de verrouillage (61, 62, 65) appartenant audit organe de manoeuvre (33) et coopérant avec lesdits moyens de verrouillage complémentaires (15) à un endroit du barillet (2) distinct de l'endroit par lequel débouche de la cavité (20), du côté opposé à ladite aiguille (31), ledit conduit (45). The device for the transfer of a medium comprises a barrel (2) and at least one transfer element (3) of said medium, said transfer element (3) comprising a conduit (45) for transferring said medium provided at one end. a needle (31), a septum (32), and an actuator (33) of said needle (31), said transfer member (3) also having locking means (61, 65) adapted to cooperate with complementary locking means (15) of said cylinder (2) for locking said needle (31) in a waiting position, said locking means (61, 62, 65) belonging to said operating member (33) and cooperating with said complementary locking means (15) at a location of the barrel (2) distinct from the place through which the cavity (20) opens, on the opposite side to said needle (31), said duct (45).

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29-09-2017 дата публикации

A kind of isolated planktonic organism halving sampling equipment

Номер: CN105372098B

本发明公开了一种隔离式浮游生物等分取样设备,旨在提供一种不仅能够有效提高浮游生物样品数量计算的工作效率,而且可以保证完整浮游生物样品数量的计算准确性的浮游生物等分取样设备。它包括机架,通过水平轴杆可转动设置在机架上的隔离筒及用于驱动隔离筒转动的旋转执行机构,隔离筒内设有若干与水平轴杆相垂直的分离隔板,分离隔板的面积小于隔离筒内腔的横截面积,且各分离隔板沿水平轴杆的轴向在隔离筒内分隔出若干个隔离槽,分离隔板上设有自适应均分机构,该自适应均分机构包括设置在分离隔板侧面上并沿水平轴杆径向延伸的径向导向孔,设置在分离隔板上并连通相连两隔离槽的平衡通孔及设置在径向导向孔内的活塞体。

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05-01-1973 дата публикации

Automated chromatographic analysis - for dangerous substances such as products of nuclear fission

Номер: FR2138461A1
Автор: [UNK]
Принадлежит: Commissariat a lEnergie Atomique CEA

In the automatic collection of multi-fraction eluate from an ion-exchange chromatography column, solution for analysis is fed into the column and followed by a series of elements, one at a time, to produce a sequence of different eluates. Collecting jars are positioned by a rotary table at the column outlet, so that each jar receives an individual eluate; heaters are provided which heat the jars during the eluation process so that evaporation of eluate is concurrent with eluation, extraction hoods being fitted to clear fumes arising during the evaporation.

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09-06-2006 дата публикации

COMPONENT SEPARATION INSTALLATION IN SEVERAL PARALLEL WAYS

Номер: FR2867089B1
Принадлежит: BIONISIS SA

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24-08-1953 дата публикации

Automatic dosing device

Номер: FR1035361A
Автор:
Принадлежит: Technicon Chromatography Corp

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25-05-1973 дата публикации

Patent FR2138461B1

Номер: FR2138461B1
Автор: [UNK]
Принадлежит: Commissariat a lEnergie Atomique CEA

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16-08-1968 дата публикации

Automatic collector

Номер: FR1536218A
Принадлежит: Commissariat a lEnergie Atomique CEA

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10-05-1996 дата публикации

Rotary-plate appts. for collection or distribution of liq. samples

Номер: FR2726653A1

The moving part is a circular horizontal plate (7) with polyethylene cups (11) fitted into holes (10) arranged in a spiral groove (12). The fixed part has a framework of two horizontal square PVC boards spaced apart by four pillars and carrying, in addn. to the plate, a rail (15) extending across it for guidance of a carriage (17).Liq. delivered by tube (21) is distributed by an electrically operated valve (22) to a curved capillary positioned above a selected cup. The latter is detected by a photoelectric cell on the carriage.

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13-01-1989 дата публикации

METHOD AND DEVICE FOR DISTRIBUTING A PRIMARY VOLUME OF A FLUID ADVANTAGEUALLY A LIQUID, IN A DETERMINED NUMBER OF SECONDARY VOLUMES HAVING A PREDEFINED RELATIONSHIP BETWEEN THEM, BY USING SYMETRICALLY DISTRIBUTED DISCHARGE ORIFICES IN A SELF DISTRIBUTION CHAMBER -MEM SYMMETRIC

Номер: FR2617963A1
Автор: [UNK]

L'invention concerne un procédé et un dispositif de répartition d'un volume primaire d'un fluide à répartir en un nombre déterminé de volumes secondaires présentant une relation prédéfinie entre eux. Ce dispositif est caractérisé en ce qu'il comprend une enceinte creuse fermée définissant une chambre de répartition de fluide à répartir pourvue d'un orifice d'admission du fluide à répartir et d'un nombre d'orifices d'évacuation du fluide à répartir équivalent au nombre de volumes secondaires désiré, ladite chambre ayant un axe de symétrie et les orifices d'évacuation étant répartis symétriquement par rapport à cet axe de symétrie, ledit dispositif étant pourvu de moyens de répartition uniformes 16, 17 assurant une alimentation et un arrêt d'alimentation simultané et uniforme des orifices d'évacuation avec une surface de séparation unique entre le fluide à répartir et l'atmosphère ou éventuellement un fluide propulseur; et de préférence des moyens 10 d'introduction d'un fluide propulseur 12 non miscible avec le fluide à répartir, sous pression, sont prévus, pour obliger le fluide à répartir à s'écouler complètement par lesdits orifices d'évacuation. L'invention fournit un dispositif versatile de répartition très précise. The invention relates to a method and a device for distributing a primary volume of a fluid to be distributed into a determined number of secondary volumes having a predefined relationship between them. This device is characterized in that it comprises a closed hollow chamber defining a distribution chamber for the fluid to be distributed provided with an inlet port for the fluid to be distributed and a number of discharge orifices for the fluid to be distributed. equivalent to the number of secondary volumes desired, said chamber having an axis of symmetry and the discharge openings being distributed symmetrically with respect to this axis of symmetry, said device being provided ...

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27-11-2015 дата публикации

METHOD FOR COLLECTING FRACTIONS IN CHROMATOGRAPHY RECEPTACLES AND ASSOCIATED DEVICE

Номер: FR3021229A1
Автор: Mohamed Shaimi
Принадлежит: PIC Solution SAS

Le procédé de collecte de fractions dans une série de réceptacles (1,2,...,72) issus d'une chromatographie liquide, gazeuse ou avec éluent supercritique, destiné à être mis en œuvre par un dispositif de collecte (100) comportant deux têtes de collecte (113,123), comporte des étapes de : a. positionnement d'une première tête de collecte sur un réceptacle N de la série de réceptacles ; b. collecte d'une fraction dans le réceptacle N avec la première tête de collecte ; c. positionnement d'une deuxième tête de collecte sur un réceptacle N+1 de la série de réceptacles, adjacent au réceptacle N ; d. collecte d'une fraction dans le réceptacle N+1 avec la deuxième tête de collecte ; e. positionnement de la première tête de collecte sur le réceptacle N+2 de la série de réceptacles, adjacent au réceptacle N+1 ; f. répétition des étapes b à e sur l'ensemble des réceptacles de la série de réceptacles.

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13-08-1976 дата публикации

Patent FR2146412B1

Номер: FR2146412B1
Автор: [UNK]
Принадлежит: Instrumentation Laboratory Co

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13-07-1978 дата публикации

SAMPLE DISTRIBUTION METHOD AND PROGRAMMABLE SAMPLE FRACTION COLLECTOR APPARATUS, FOR IMPLEMENTING THIS PROCESS

Номер: FR2374632A1
Автор: Lage Allan Nordlund
Принадлежит: Pharmacia Fine Chemicals AB

La présente invention concerne un procédé pour distribuer des échantillons dans des récipients d'essai, ainsi qu'un appareil pour la mise en oeuvre de ce procédé. L'appareil collecteur de fraction d'échantillons est entièrement automatique et permet une distribution d'échantillons dans des récipients de différentes dimensions, disposés en rangées et en colonnes. Les échantillons sont distribués selon un mode de remplissage goutte à goutte. Application à l'analyse chimique automatisée. The present invention relates to a method for dispensing samples into test vessels, as well as an apparatus for carrying out this method. The fractional sample collection device is fully automatic and allows samples to be dispensed into containers of different sizes, arranged in rows and columns. The samples are dispensed in a drip filling mode. Application to automated chemical analysis.

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16-05-2008 дата публикации

DEVICE AND INSTALLATION FOR COLLECTING AND TESTING THE WATER OF A BASIN, SUCH AS A SWIMMING POOL

Номер: FR2908518A1
Принадлежит: COVALTECH

Ce dispositif (10) comporte :- une barrette (16) délimitant des compartiments (18) contenant chacun un réactif,- des moyens automatisés (40, 62, 64, 78, 82) de remplissage des compartiments par de l'eau prélevée depuis une voie (42) de circulation d'eau provenant du bassin, pour former des solutions aqueuses de mélange,- des moyens de mesure de caractéristiques physico-chimiques des solutions aqueuses,- un châssis (10) de support des moyens de remplissage et des moyens de mesure, et- des moyens (112, 120) d'entraînement motorisé de la barrette par rapport au châssis depuis une configuration de repos (configuration B), dans laquelle les compartiments sont déconnectés des moyens de remplissage, à une configuration de test qualitatif (configuration D) dans laquelle chaque solution aqueuse est soumise aux moyens de mesure.L'automatisation et la motorisation de ce dispositif le rendent facile d'utilisation, tout en garantissant de bonnes précision et répétabilité des mesures de la qualité de l'eau. This device (10) comprises: - a bar (16) delimiting compartments (18) each containing a reagent, - automated means (40, 62, 64, 78, 82) for filling the compartments with water taken from a channel (42) for circulating water from the pool to form aqueous mixing solutions; means for measuring the physicochemical characteristics of the aqueous solutions; a frame (10) for supporting the filling means and measuring means, and motorized drive means (112, 120) of the bar relative to the frame from a rest configuration (configuration B), in which the compartments are disconnected from the filling means, to a test configuration qualitative (configuration D) in which each aqueous solution is subjected to the measuring means. The automation and the motorization of this device make it easy to use, while guaranteeing good accuracy and repeatability of the measurements. es of water quality.

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09-04-1976 дата публикации

Automatic sampler for waste water - requiring no energy source and having lightweight non-bulky properties

Номер: FR2284872A1
Автор: [UNK]
Принадлежит: Charret Jean

Automatic sampler for waste water comprises a pipe arranged to allow utilisation of the loss of load for distributing the samples, without using any additional energy source. The pipe extends spirally, with its loops disposed in vertical planes and alternating with discharge openings which may be directed downwardly, to the left or right and in a horizontal or oblique plane. The air outlet pipes for evacuating the receptacles have their upper ends disposed at a higher level that the main feed pipe.

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27-12-1996 дата публикации

Automatic receiver for fractions from crude oil distn. analysis

Номер: FR2735783A1
Автор: Remy Geoffray
Принадлежит: TECHTRION

Dispositif du type comprenant un récipient de recueil intermédiaire des distillats, thermostaté, et équipé d'au moins une électrovanne d'entrée des distillats et d'une électrovanne de sortie de ceux-ci vers différents récipients de recueil final. Selon l'invention, entre le récipient de recueil intermédiaire (3) et les récipients (5) de recueil final est disposé un sas (4) comportant, à sa partie supérieure, un orifice (33) d'amenée des distillats depuis le récipient de recueil intermédiaire (3), et un orifice (34) permettant, à l'aide de trois vannes (35, 36, 37), de relier l'intérieur du sas (4) respectivement avec une source de vide, avec l'atmosphère et avec l'installation de distillation, pour réaliser une équipression avec cette dernière, et à sa partie inférieure, une électrovanne (38) de transfert du distillat vers un collecteur pour récipients de recueil final.

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09-08-1932 дата публикации

sampler

Номер: FR730248A
Автор:
Принадлежит: Appareils et Evaporateurs Kestner SA

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31-05-2019 дата публикации

APPARATUS FOR SEPARATING CHEMICAL COMPOUNDS PRESENT IN A SAMPLE WITH A CORROSIVE ELUANT

Номер: FR3033261B1

La présent invention concerne un appareil pour séparer des composés chimiques présents dans un échantillon avec un éluant corrosif à travers une colonne de séparation comprenant un dispositif de pompage de l'éluant corrosif et/ou de l'échantillon dans la colonne de séparation, un capteur de niveau, un collecteur et un contrôleur programmable relié au capteur pour déclencher le dispositif de pompage lorsque le signal est reçu; elle porte également sur un procédé de séparation et de récupération mis en œuvre à l'aide dudit appareil. The present invention relates to an apparatus for separating chemical compounds present in a sample with a corrosive eluent through a separation column comprising a device for pumping the corrosive eluent and / or the sample in the separation column, a sensor a collector and a programmable controller connected to the sensor for triggering the pumping device when the signal is received; it also relates to a separation and recovery process implemented using said apparatus.

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30-08-1963 дата публикации

pulse transmitter in particular for chromatographic analysis apparatus

Номер: FR1336579A
Автор:
Принадлежит: Czech Academy of Sciences CAS

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23-11-2006 дата публикации

measuring device

Номер: DE19704237B4
Принадлежит: TDK Micronas GmbH

Messeinrichtung zur Messung oder Untersuchung physiologischer und/oder physikalischer Parameter an biologischem Material oder von in einem Analyten enthaltenen chemischen und bioaktiven Substanzen, mit mehreren elektrischen oder elektronischen Sensoranordnungen, die einen mit einer Auswerteeinrichtung verbindbaren Messausgang aufweisen, sowie mit einer Beprobungseinrichtung zum parallelen, separaten Zuführen von Beprobungsmedium zu jeder Sensoranordnung, und wobei die Beprobungseinrichtung jeweils einer Sensoranordnung zugeordnete Beprobungskanäle mit einer Abgabeöffnung zum Zuführen von Beprobungsmedien aufweist, dadurch gekennzeichnet, dass die Beprobungseinrichtung (4) ein rechenartiges Beprobungsteil (12) aufweist, das an einer gemeinsamen Schwenkachse (16) angreifende Schwenkfinger (13) hat, an deren Ende sich jeweils die Abgabeöffnung (15) befindet, derart, dass die Abgabeöffnungen (15) in eine Abgabe- oder Beprobungsstellung jeweils bei einer Sensoranordnung (2) und in eine zur Sensoranordnung (2) beabstandete Ausgangs- oder Ruhestellung bringbar sind. measuring device for the measurement or examination of physiological and / or physical Parameter on biological material or contained in an analyte chemical and bioactive substances, with multiple electrical or electronic sensor arrangements, the one with an evaluation have connectable measuring output, as well as with a sampling device for parallel, separate feeding from sampling medium to each sensor array, and wherein the sampling device each associated with a sensor array sampling channels with a Dispensing opening to Respectively of sampling media, characterized in that the Sampling device (4) a rake-type sampling part (12) having, on a common pivot axis (16) attacking Pivoting finger (13) has, at the end of each of the discharge opening (15) such that the discharge openings (15) are arranged in a discharge or sampling position in each case in a sensor arrangement (2) and in a sensor arrangement (2) spaced ...

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26-08-1975 дата публикации

Vacuum-operated sampler and distributor for multiple sampling operation

Номер: US3901084A
Автор: Harrison D Brailsford
Принадлежит: Harrison D Brailsford

The sampler includes a distributor with first and second members movable relative to each other in several specific positions. In each position a transfer port in one member is aligned with a different port in the other member. Each of the latter ports is connected to a separate sample receptacle, and the transfer port is connected to the intake line of a vacuum pump. A bellows and a valve are also connected to the intake line to the pump, and the valve is actuated to open and close at certain times relative to a cycle of operation in which the pump draws into the system a sample, which may be gas or liquid depending on the construction of the sampler. When the valve is closed, the pump draws air out of the bellows causing the latter to contract and operate an advancement device to align the transfer port with the next port in the other member.

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19-01-2004 дата публикации

Method and device for analyzing a blood sample

Номер: AU2003258791A1
Автор: Roger Le Comte
Принадлежит: ABX SA

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27-10-2008 дата публикации

FACILITY COLLECTOR WITH ADJUSTABLE PALLET

Номер: RU2007112508A

1. Сборник фракций, содержащийопорную систему,каретку, поддерживаемую опорной системой с возможностью перемещения,удлинитель, присоединенный к каретке,распределительную головку, которая присоединена к удлинителю с возможностью перемещения и которая может перемещаться с кареткой относительно опорной системы в первой плоскости, иоснование сборника, присоединенное с возможностью перемещения к опорной системе, причем основание сборника может перемещаться во второй плоскости, перпендикулярной первой плоскости, без перемещения опорной системы.2. Сборник по п.1, в котором опорная система содержит левую стойку, правую стойку и верхнюю перемычку.3. Сборник по п.2, в котором опорная система дополнительно содержит переднюю перемычку.4. Сборник по п.2, в котором основание сборника содержит поддон для удерживания сосудов-сборников и держатели, которые выходят из поддона с обеспечением крепления к опорной системе.5. Сборник по п.4, в котором поддон предназначен для поддержки по меньшей мере одной подставки, которая предназначена для удержания по меньшей мере одного сосуда-сборника.6. Сборник по п.4, в котором левая стойка содержит первый штифт, правая стойка содержит второй штифт, а каждый из держателей основания сборника содержит точку крепления, предназначенную для размещения в ней первого штифта или второго штифта.7. Сборник по п.6, в котором точка крепления является пазом.8. Сборник по п.6, в котором точка крепления является отверстием.9. Сборник по п.6, в котором первый штифт и второй штифт фиксированы.10. Сборник по п.4, в котором левая стойка имеет первое отверстие, правая стойка имеет второе отверстие, а каждый из держателе� ÐÎÑÑÈÉÑÊÀß ÔÅÄÅÐÀÖÈß (19) RU (11) 2007 112 508 (13) A (51) ÌÏÊ B01D 15/08 (2006.01) ÔÅÄÅÐÀËÜÍÀß ÑËÓÆÁÀ ÏÎ ÈÍÒÅËËÅÊÒÓÀËÜÍÎÉ ÑÎÁÑÒÂÅÍÍÎÑÒÈ, ÏÀÒÅÍÒÀÌ È ÒÎÂÀÐÍÛÌ ÇÍÀÊÀÌ (12) ÇÀßÂÊÀ ÍÀ ÈÇÎÁÐÅÒÅÍÈÅ (21), (22) Çà âêà: 2007112508/15, 08.09.2005 (71) Çà âèòåëü(è): ÄÆÈËÑÎÍ, ÈÍÊ. (US) (30) Êîíâåíöèîííûé ïðèîðèòåò: 10.09.2004 US 60/609,105 (43) Äàòà ïóáëèêàöèè çà ...

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08-08-2006 дата публикации

Fraction collector for composition analysis

Номер: US7086279B2
Принадлежит: Waters Investments Ltd

A method and apparatus for controlling fraction collection in an eluent stream flowing from an LC column. A triggering detector recognizes the presence of a target substance according to characteristics of chromatographic peaks in the eluent stream and initiates a delay timer to trigger the fraction collector. A waste stream detector is disposed at any distance from the fraction collector to detect peaks in the waste stream flowing from a fraction collector. The signature of fraction collector actuation is seen by the waste stream detector, permitting the delay time to be adjusted for optimal collection of the target compound. The presence or absence of a peak or the characteristics of a remnant peak detected by the waste stream detector are used to confirm that the target component of the eluent stream was collected as intended by the fraction collector.

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Sampling apparatus

Номер: GB1386106A
Автор:
Принадлежит: SAMPFLO Ltd

1386106 Sampling liquids SAMPFLO Ltd 1 Oct 1973 [10 Nov 1972] 51903/72 Heading B8N Apparatus for sampling effluent comprises a rotary table 10 supporting a circumferential array of containers 12 for successive movement past the outlet of a discharge conduit 22, and a collector ring 31 interposed between the outlet and the containers and provided with openings 32 which register with the containers. The collector ring 31 and the containers may be mounted on the rotary table 10 with the openings 32 separated by inverted V portions. A pump may be controlled by a timer for periodically extracting water from a stream, passing it through a pipe 13 and directing it through an outlet 26 to a disposal pipe 23. A solenoid 21 is provided for flexing the outlet 26 so that it delivers down the discharge conduit 22 into the divisions of the collector ring 31. The samples may be taken while the table 10 rotates continuously bringing the containers in turn into resistor with the discharge conduit 22; the table may hold twelve containers 12 and arranged to rotate at the rate of one revolution in twelve hours so that each container would be in a position to receive a sample for a period of one hour. If desired, the collector ring may be separate from the table with the containers resting on the table beneath the collector ring.

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DEVICE FOR PRECISE FLUID DIVIDING

Номер: DE2251397A1
Принадлежит: Damon Corp

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Effluent isolating device - of fractions from column chromatography

Номер: DE2110814A1
Автор: Klaus Dr Keck
Принадлежит: Individual

Electro-mechanical device, using operational amplifier and logic circuit, drives fraction collector such that each eluted fraction, or required peak, is collected separately in a single container, unwanted fractions being pooled. Instrument responds to a change in signal relative to a preset value.

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Fraction collector

Номер: EP0204329A2

A fraction collector in which the relative movement of the fractionating column drain and the fraction receiving vessels can be altered by pneumatic drive, locking and control means. <IMAGE>

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Purification preparative equipment

Номер: JP4615101B2
Автор: 徹 茗荷谷

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SAMPLE DIVIDER

Номер: DE3637757A1
Принадлежит: Krupp Polysius AG

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Chemical sampling apparatus

Номер: US3484206A
Автор: Herbert Loebl
Принадлежит: Joyce Loebl and Co Ltd

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Generation and use of discovery ion currents in mass spectrometry

Номер: JP7229163B2
Принадлежит: Advion Inc

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Chromatograph/mass spectrometer

Номер: US7269994B2
Автор: Yoshikatsu Umemura
Принадлежит: Shimadzu Corp

The present invention provides a chromatograph/mass spectrometer capable of producing a composite chromatogram from plural chromatogram signals without causing the baseline level to rise or the intensity of the chromatogram peak to decrease. The chromatograph/mass spectrometer includes a chromatograph unit for separating a sample into components in the order of time, a mass spectrometer unit for analyzing the components of the sample, and a signal generator for producing a signal carrying a chromatogram obtained by the analysis. It also includes a chromatogram composer for receiving signals of plural chromatograms simultaneously measured under different conditions, for choosing the largest value of the plural signals for each point in time, and for integrating the chosen values to produce a composite chromatogram.

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Specimen distributor for liq. chromatography, e.g. with packed separating columns - has distribution plate with channels on top and bottom surfaces connected by bores distributed over surface

Номер: DE4118501A1
Принадлежит: SAEULENTECHNIK DR ING HERBERT

A specimen distributor for transverse distribution of axially introduced liquid specimens onto the surfaces of separating media contains a distribution plate (1) whose centre acts as an impact plate (6) and whose top and bottom surfaces have channels (4,5,9) connected via bores (7) distributed over the surface. The plate is of thin, cylindrical form and the channels and bores are of minimal vol. A concentric channel system on the upper surface can have radial connecting channels. USE/ADVANTAGE - E.g. for liquid chromatography with packed separating columns or polymer membranes. Distributor developed to ensure optimal specimen distribution over surface and max. selectivity of separating columns or membranes.

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