Antibodies directed against amyloid-beta peptide and methods of using same
Номер патента: NZ552480A
Опубликовано: 29-01-2010
Автор(ы): Arnon Rosenthal, Jan Markus Grimm, Jaume Pons, Wei-Hsien Ho
Принадлежит: Rinat Neuroscience Corp
Опубликовано: 29-01-2010
Автор(ы): Arnon Rosenthal, Jan Markus Grimm, Jaume Pons, Wei-Hsien Ho
Принадлежит: Rinat Neuroscience Corp
Реферат: Provided is the use of an antibody that specifically binds to a beta-amyloid peptide or an aggregated form of a beta-amyloid peptide, wherein the antibody comprises at least one CDR region selected from the group consisting of a specified amino acid sequence of heavy or light chain CDR1, CDR2 or CDR3 region for the manufacture of a medicament for the treatment of a disease characterized by aberrant deposition of beta-amyloid in a subject. Further provided are variants of the antibodies, polynucleotides encoding the antibodies and methods of making the antibodies.
Antibodies directed against amyloid-beta peptide and methods using same
Номер патента: US20120269805A1. Автор: Arnon Rosenthal,Jaume Pons,Wei-Hsien Ho,Jan Markus Grimm. Владелец: Rinat Neuroscience Corp. Дата публикации: 2012-10-25.