BICYCLIC HPK1 INHIBITORS.

BICYCLIC HPK1 INHIBITORS

Номер патента: US20220169644A1
Опубликовано: 02-06-2022
Автор(ы): ADELINET Christophe Denis Pascal, COUPA Sophie, EDWARDS James Patrick, Mevellec Laurence Anne, VIALARD Jorge Eduardo, Wroblowski Berthold
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Рисунок 1. Взаимосвязь патентов (ближайшие 20).

Pyrido[3,2-d]pyrimidines as hpk1 inhibitors

Номер патента: AU2023254182A1. Автор: BIN Li,Momar TOURE,Yanping Wang,Theresa Johnson,Constantin Neagu,James Cummings,Eugene Chekler,Emily FRIIS. Владелец: Merck Patent GmBH. Дата публикации: 2024-10-03.

Pyrido[3,2-d]pyrimidines as hpk1 inhibitors

Номер патента: WO2023201185A1. Автор: BIN Li,Momar TOURE,Yanping Wang,Theresa Johnson,Constantin Neagu,James Cummings,Eugene Chekler,Emily FRIIS. Владелец: Merck Patent GmBH. Дата публикации: 2023-10-19.

Substituted 6-azabenzimidazole compounds as hpk1 inhibitors

Номер патента: EP4371987A1. Автор: Jeff Zablocki,Musong Kim,Rao V. Kalla,Sundaramoorthi Swaminathan,Gary B. Phillips,Jayaraman Chandrasekhar,Julian A. Codelli,Suet C. YEUNG,Thao D. Perry,Gayatri BALAN,Mark J. Bartlett,John H. Conway,Jennifer L. COSMAN,Seung H. Lee,Jennifer R. Lo,Jennifer A. Loyer-Drew,Scott A. Mitchell,Patrick J. SALVO,Joshua J. Van Veldhuizen,Zachary A. KASUN. Владелец: Gilead Sciences Inc. Дата публикации: 2024-05-22.

Indazoles as hematopoietic progenitor kinase 1 (hpk1) inhibitors and methods of using same

Номер патента: AU2021347913A9. Автор: Jinhwa Lee,Misoon KIM,Suyeon JO,Keonseung Lim,A Yeong Park,Jae Eun Kim,Seung Mook Lim,Gadhe Changdev GORAKSHNATH,Hwajung NAM,Yeonguk JEON,Yejin HWANG. Владелец: 1St Biotherapeutics Inc. Дата публикации: 2024-06-27.

Hpk1 inhibitors and uses thereof

Номер патента: EP3994133A4. Автор: HAO LIU,SONG Feng,Wei Huang,Xiaotian Zhu,Hua Zhou,Lei Wu,Wenge Zhong,Rongqiang LIU,Kate Xin Wen. Владелец: Qilu Regor Therapeutics Inc. Дата публикации: 2023-11-22.

Substituted 6-azabenzimidazole compounds as hpk1 inhibitors

Номер патента: IL282535B1. Автор: . Владелец: Gilead Sciences Inc. Дата публикации: 2024-01-01.

INDAZOLES AS HEMATOPOIETIC PROGENITOR KINASE 1 (HPK1) INHIBITORS AND METHODS USING SAME

Номер патента: US20220098193A1. Автор: Lee Jinhwa,Kim Jae Eun,JO Suyeon,LIM Keonseung,PARK A Yeong,GORAKSHNATH Gadhe Changdev,NAM Hwajung,JEON Yeonguk,HWANG Yejin,KIM Misoon,LIM Seung Mook. Владелец: . Дата публикации: 2022-03-31.

Hpk1 inhibitors

Номер патента: US20220177458A1. Автор: Laurence Anne Mevellec,James Patrick Edwards,Sophie Coupa,Jorge Eduardo Vialard,Berthold Wroblowski,Christophe Denis Pascal ADELINET. Владелец: Janssen Research and Development LLC. Дата публикации: 2022-06-09.

AMINOPYRAZINE COMPOUNDS AS HPK1 INHIBITOR AND THE USE THEREOF

Номер патента: US20220289712A1. Автор: Liu Ye,LI Jing,Wang Zhiwei,XU Sanjia,SUN Hanzi. Владелец: . Дата публикации: 2022-09-15.

Azalactam Compounds as HPK1 Inhibitors

Номер патента: US20200172539A1. Автор: Nair Sajiv Krishnan,Jalaie Mehran,Tuttle Jamison Bryce,McTigue Michele Ann,Kania Robert Steven,Gallego Rebecca Anne,Ahmad Omar Khaled,Johnson Ted William,Zhou Dahui,Del Bel Matthew L.,Zhou Ru,He Mingying. Владелец: PFIZER INC.. Дата публикации: 2020-06-04.

Azalactam Compounds as HPK1 Inhibitors

Номер патента: US20220401424A1. Автор: Nair Sajiv Krishnan,Jalaie Mehran,Tuttle Jamison Bryce,McTigue Michele Ann,Kania Robert Steven,Gallego Rebecca Anne,Zhou Dahui,Del Bel Matthew L.,Zhou Ru,He Mingying,Cho-Schultz Sujin,Barber Joyann,Schmitt Anne-Marie Dechert. Владелец: PFIZER INC.. Дата публикации: 2022-12-22.

2, 3-dihydro-1H-pyrrolo [3,4-c ] pyridin-1-one derivatives as HPK1 inhibitors for the treatment of cancer

Номер патента: CN113316576A. Автор: S·K·奈尔,R·S·卡尼亚,M·何,R·周,D·周,R·A·加莱戈,O·K·艾哈迈德,T·W·约翰逊,J·B·塔特尔,M·雅拉耶,M·A·麦克蒂格,M·L·戴尔贝尔,A-M·D·施米特. Владелец: PFIZER INC. Дата публикации: 2021-08-27.

2,3-dihydro-1H-pyrrolo(3,4-c)pyridin-1-one derivatives as HPK1 inhibitors for the treatment of cancer

Номер патента: AU2019378184A1. Автор: Robert Steven Kania,Mingying He,Ru Zhou,Sajiv Krishnan Nair,Mehran Jalaie,Ted William Johnson,Omar Khaled AHMAD,Michele Ann Mctigue,Jamison Bryce Tuttle,Dahui Zhou,Matthew L. DEL BEL,Rebecca Anne Gallego,Anne-Marie Dechert Schmitt. Владелец: PFIZER INC. Дата публикации: 2021-05-27.

Substituted 6-azabenzimidazole compounds as hpk1 inhibitors

Номер патента: CA3117556A1. Автор: Jeff Zablocki,Musong Kim,Rao V. Kalla,Sundaramoorthi Swaminathan,Gary B. Phillips,Jayaraman Chandrasekhar,Julian A. Codelli,Suet C. YEUNG,Thao D. Perry,Gayatri BALAN,Mark J. Bartlett,John H. Conway,Jennifer L. COSMAN,Seung H. Lee,Jennifer R. Lo,Jennifer A. Loyer-Drew,Scott A. Mitchell,Patrick J. SALVO,Joshua J. Van Veldhuizen,Zachary A. KASUN. Владелец: Gilead Sciences Inc. Дата публикации: 2020-05-07.

Anilinopyrimidines as haematopoietic progenitor kinase 1 (hpk1) inhibitors

Номер патента: EP3548479A1. Автор: Xiaotian Zhu,Wei-Sheng Huang,Yun Zhang,Willmen Youngsaye,Erin GENO. Владелец: Ariad Pharmaceuticals Inc. Дата публикации: 2019-10-09.

2,3-dihydro-1h-pyrrolo[3,4-c]pyridin-1-one derivatives as hpk1 inhibitors for the treatment of cancer

Номер патента: PH12021551117A1. Автор: Robert Steven Kania,Mingying He,Ru Zhou,Sajiv Krishnan Nair,Mehran Jalaie,Ted William Johnson,Omar Khaled AHMAD,Michele Ann Mctigue,Jamison Bryce Tuttle,Dahui Zhou,Rebecca Anne Gallego,Anne-Marie Dechert Schmitt,Bel Matthew L Del. Владелец: Pfizer. Дата публикации: 2021-11-22.

Bicyclic compound as hpk1 inhibitor and application thereof

Номер патента: WO2022171034A1. Автор: 周峰,刘磊,唐任宏,任晋生,刘扬,刘力锋,唐锋. Владелец: 江苏先声药业有限公司. Дата публикации: 2022-08-18.

Novel HPK1 inhibitor and preparation method and application thereof

Номер патента: CN115244050A. Автор: 张建华,刘胜洋,江磊,冯志勇,金贤,石倩,寿建勇,徐圆,赵海霞. Владелец: Shanghai Ennovabio Pharmaceuticals Co Ltd. Дата публикации: 2022-10-25.

Anilinopyrimidine AS as a hematopoietic precursor kinase 1 (HPK1) inhibitor

Номер патента: JP7025426B2. Автор: ウェイ－シェンファン，,ユンジャン，,ウィルメンヤングセイ，,シャオティアンジュー，,エリンゲーノ，. Владелец: アリアドファーマシューティカルズ，インコーポレイテッド. Дата публикации: 2022-02-24.

Azaindoles as HPK1 inhibitor

Номер патента: CN110402248A. Автор: B·陈,魏斌清,胡永韩,S·马尔霍特拉,E·甘西亚,T·赫夫隆,L·加扎德,M·兰奇伯里,E·西沃德,A·麦迪. Владелец: F Hoffmann La Roche AG. Дата публикации: 2019-11-01.

Azalactam compounds as hpk1 inhibitors

Номер патента: CR20220548A. Автор: Robert Steven Kania,Mingying He,Ru Zhou,Sajiv Krishnan Nair,Sujin Cho-Schultz,Mehran Jalaie,Michele Ann Mctigue,Jamison Bryce Tuttle,Dahui Zhou,Rebecca Anne Gallego,Anne-Marie Dechert Schmitt,Bel Matthew L Del,Joyann Barber. Владелец: Pfizer. Дата публикации: 2022-12-12.

AZALACTAM COMPOUNDS AS HPK1 INHIBITORS

Номер патента: DOP2021000088A. Автор: Jalaie Mehran,Zhou Dahui,Zhou Ru,He Mingying,Steven Kania Robert,Khaled Ahmad Omar,Ann Mctigue Michele,Krishnan Nair Sajiv,Bryce Tuttle Jamison,William Johnson Ted,Anne Gallego Rebecca,L Del Bel Matthew,Dechert Schmitt Anne-Marie. Владелец: Pfizer. Дата публикации: 2021-06-30.

Azalactam compounds as hpk1 inhibitors

Номер патента: CA3061392A1. Автор: Robert Steven Kania,Mingying He,Ru Zhou,Sajiv Krishnan Nair,Mehran Jalaie,Ted William Johnson,Omar Khaled AHMAD,Jamison Bryce Tuttle,Dahui Zhou,Michele MCTIGUE,Rebecca Anne Gallego,Anne-Marie Dechert Schmitt,Matthew Del Bel. Владелец: PFIZER INC. Дата публикации: 2020-05-15.

Azalactam compounds as HPK1 inhibitors

Номер патента: AU2021265578B2. Автор: Robert Steven Kania,Mingying He,Ru Zhou,Sajiv Krishnan Nair,Sujin Cho-Schultz,Mehran Jalaie,Michele Ann Mctigue,Jamison Bryce Tuttle,Dahui Zhou,Matthew L. DEL BEL,Rebecca Anne Gallego,Anne-Marie Dechert Schmitt,Joyann Barber. Владелец: PFIZER INC. Дата публикации: 2024-03-28.

2,3-dihydro-1h-pyrrolo[3,4-c]pyridin-1-one derivatives as hpk1 inhibitors for the treatment of cancer

Номер патента: ZA202103099B. Автор: Robert Steven Kania,Mingying He,Ru Zhou,Sajiv Krishnan Nair,Mehran Jalaie,Ted William Johnson,Omar Khaled AHMAD,Michele Ann Mctigue,Jamison Bryce Tuttle,Dahui Zhou,Rebecca Anne Gallego,Anne-Marie Dechert Schmitt,Bel Matthew L Del. Владелец: Pfizer. Дата публикации: 2023-11-29.

Substituted 6-azabenzimidazole compounds as hpk1 inhibitors

Номер патента: EP3873903B1. Автор: Jeff Zablocki,Musong Kim,Rao V. Kalla,Sundaramoorthi Swaminathan,Gary B. Phillips,Jayaraman Chandrasekhar,Julian A. Codelli,Suet C. YEUNG,Thao D. Perry,Gayatri BALAN,Mark J. Bartlett,John H. Conway,Jennifer L. COSMAN,Seung H. Lee,Jennifer R. Lo,Jennifer A. Loyer-Drew,Scott A. Mitchell,Patrick J. SALVO,Joshua J. Van Veldhuizen,Zachary A. KASUN. Владелец: Gilead Sciences Inc. Дата публикации: 2024-01-24.

Substituted indazoles as hematopoietic progenitor kinase 1 (HPK1) inhibitors

Номер патента: US11834467B2. Автор: Jinhwa Lee,Misoon KIM,Suyeon JO,Keonseung Lim,A Yeong Park,Jae Eun Kim,Seung Mook Lim,Gadhe Changdev GORAKSHNATH,Hwajung NAM,Yeonguk JEON,Yejin HWANG. Владелец: 1St Biotherapeutics Inc. Дата публикации: 2023-12-05.

2,3-dihydro-1h-pyrrolo[3,4-c]pyridin-1-on-derivater som hpk1-inhibitorer til behandling af cancer

Номер патента: DK3880676T3. Автор: Robert Steven Kania,Mingying He,Ru Zhou,Sajiv Krishnan Nair,Mehran Jalaie,Ted William Johnson,Omar Khaled AHMAD,Michele Ann Mctigue,Jamison Bryce Tuttle,Dahui Zhou,Rebecca Anne Gallego,Anne-Marie Dechert Schmitt,Bel Matthew L Del. Владелец: Pfizer. Дата публикации: 2023-09-04.

Azalactam Compounds as HPK1 Inhibitors

Номер патента: US20220401424A1. Автор: Robert Steven Kania,Mingying He,Ru Zhou,Sajiv Krishnan Nair,Sujin Cho-Schultz,Mehran Jalaie,Michele Ann Mctigue,Jamison Bryce Tuttle,Dahui Zhou,Matthew L. DEL BEL,Rebecca Anne Gallego,Anne-Marie Dechert Schmitt,Joyann Barber. Владелец: PFIZER INC. Дата публикации: 2022-12-22.

Heterocyclic compounds useful as hpk1 inhibitors

Номер патента: WO2023138612A1. Автор: Hui Yang,Haiquan Fang,Xiaolei Liu. Владелец: Silexon Ai Technology Co., Ltd.. Дата публикации: 2023-07-27.

Substituted 6-azabenzimidazole compounds as hpk1 inhibitors

Номер патента: IL282535B2. Автор: . Владелец: Gilead Sciences Inc. Дата публикации: 2024-05-01.

Indazoles as hematopoietic progenitor kinase 1 (hpk1) inhibitors and methods using same

Номер патента: US20220098193A1. Автор: Jinhwa Lee,Misoon KIM,Suyeon JO,Keonseung Lim,A Yeong Park,Jae Eun Kim,Seung Mook Lim,Gadhe Changdev GORAKSHNATH,Hwajung NAM,Yeonguk JEON,Yejin HWANG. Владелец: 1St Biotherapeutics Inc. Дата публикации: 2022-03-31.

Indazoles as hematopoietic progenitor kinase 1 (hpk1) inhibitors and methods of using same

Номер патента: EP4217358A1. Автор: Jinhwa Lee,Misoon KIM,Suyeon JO,Keonseung Lim,A Yeong Park,Jae Eun Kim,Seung Mook Lim,Gadhe Changdev GORAKSHNATH,Hwajung NAM,Yeonguk JEON,Yejin HWANG. Владелец: 1St Biotherapeutics Inc. Дата публикации: 2023-08-02.

Indazoles as hematopoietic progenitor kinase 1 (hpk1) inhibitors and methods using same

Номер патента: US20220098219A1. Автор: Jinhwa Lee,Misoon KIM,Suyeon JO,Keonseung Lim,A Yeong Park,Jae Eun Kim,Seung Mook Lim,Gadhe Changdev GORAKSHNATH,Hwajung NAM,Yeonguk JEON,Yejin HWANG. Владелец: 1St Biotherapeutics Inc. Дата публикации: 2022-03-31.

Hpk1 inhibitors and uses thereof

Номер патента: EP4175951B1. Автор: HAO LIU,SONG Feng,Wei Huang,Xiaotian Zhu,Hua Zhou,Lei Wu,Wenge Zhong,Rongqiang LIU,Kate Xin Wen. Владелец: Regor Pharmaceuticals Inc. Дата публикации: 2024-05-01.

Hpk1 inhibitors and uses thereof

Номер патента: US20230339896A1. Автор: HAO LIU,SONG Feng,Wei Huang,Xiaotian Zhu,Hua Zhou,Lei Wu,Wenge Zhong,Rongqiang LIU,Kate Xin Wen. Владелец: Regor Pharmaceuticals Inc. Дата публикации: 2023-10-26.

Azalactam Compounds as HPK1 Inhibitors

Номер патента: US20240197703A1. Автор: Robert Steven Kania,Mingying He,Ru Zhou,Sajiv Krishnan Nair,Sujin Cho-Schultz,Mehran Jalaie,Michele Ann Mctigue,Jamison Bryce Tuttle,Dahui Zhou,Matthew L. DEL BEL,Rebecca Anne Gallego,Anne-Marie Dechert Schmitt,Joyann Barber. Владелец: PFIZER INC. Дата публикации: 2024-06-20.

Heteroaryl compounds as hpk1 inhibitors and methods of using same

Номер патента: WO2023137406A1. Автор: Jianming Bao,Yongkui Sun,Weiguo QUAN,Koc Kan Ho,Weiping Ma,Mengchao Shi. Владелец: Foshan Ionova Biotherapeutics Co., Inc.. Дата публикации: 2023-07-20.

Tetrahydropyrido[3,4-d]pyrimidines compounds as hpk1 inhibitors

Номер патента: WO2023220541A1. Автор: BIN Li,Momar TOURE,Yufang Xiao,Yanping Wang,Theresa Johnson,Satenig Guler,Constantin Neagu,Emily FRIIS,Maria DIPOTO,Andrea UNZUE-LOPEZ. Владелец: Merck Patent GmBH. Дата публикации: 2023-11-16.

TETRAHYDROPYRIDO[3,4-d]PYRIMIDINES AS HPK1 INHIBITORS

Номер патента: US20240025922A1. Автор: BIN Li,Momar TOURE,Yufang Xiao,Yanping Wang,Theresa Johnson,Satenig Guler,Constantin Neagu,Andrea Unzue Lopez,Emily FRIIS,Maria DIPOTO. Владелец: Merck Patent GmBH. Дата публикации: 2024-01-25.

Hpk1 inhibitors and methods of use thereof

Номер патента: WO2024081385A1. Автор: Xuelei Yan,Manmohan Reddy Leleti,Jay Patrick POWERS,Ehesan Ul Sharif,Joice THOMAS,Pradeep NAREDDY,Sandeep DHANJU,Padmanabha V. KATTAMURI. Владелец: Arcus Biosciences, Inc.. Дата публикации: 2024-04-18.

Solid forms of an HPK1 inhibitor

Номер патента: US11787784B2. Автор: William Frietze,Zhongjiang JIA. Владелец: Incyte Corp. Дата публикации: 2023-10-17.

2'-(quinolin-3-yl)-5',6'-dihydrospiro[azetidine-3,4'-pyrrolo[1,2-b]pyrazole]-1-carboxylate derivatives and related compounds as map4k1 (hpk1) inhibitors for the treatment of cancer

Номер патента: WO2021249913A9. Автор: Peng Cheng,Lars Wortmann,Ulf Bömer,Ulrich LÜCKING,Judith GÜNTHER,Gabriele Leder,Rienk Offringa,Xuewei Wang,Detlef STÖCKIGT,Steffen Müller,Jeffrey Stuart MOWAT,Rafael CARRETERO,Anders Roland FRIBERG,Yuanyuan YAN,Lara Patricia KUHNKE. Владелец: Bayer Aktiengesellschaft. Дата публикации: 2022-02-03.

Combination of hpk1 inhibitor and axl inhibitor in cancer therapy

Номер патента: WO2024206869A2. Автор: Hua Wang,Huamin Wang. Владелец: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM. Дата публикации: 2024-10-03.

Combination of hpk1 inhibitor and axl inhibitor in cancer therapy

Номер патента: WO2024206869A3. Автор: Hua Wang,Huamin Wang. Владелец: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM. Дата публикации: 2024-11-07.

Hpk1 inhibitors and methods of using same

Номер патента: NZ738268A. Автор: Yong Liu,Radoslaw Laufer,Heinz W Pauls,Peter Brent Sampson,Sze-Wan Li,Narendra Kumar B Patel,Yunhui Lang,Grace Ng. Владелец: Univ Health Network. Дата публикации: 2024-04-26.

Hpk1 inhibitors, preparation method and application thereof

Номер патента: CA3097949C. Автор: Xuebin Liao. Владелец: Zhuhai Yufan Biotechnologies Co Ltd. Дата публикации: 2024-04-23.

HPK1 inhibitors, preparation method and application thereof

Номер патента: AU2019260159B2. Автор: Xuebin Liao. Владелец: Zhuhai Yufan Biotechnologies Co Ltd. Дата публикации: 2024-06-06.

HPK1 inhibitors, preparation method and application thereof

Номер патента: US11999725B2. Автор: Xuebin Liao. Владелец: Zhuhai Yufan Biotechnologies Co Ltd. Дата публикации: 2024-06-04.

Substituted pyrazine-2-carboxamides as hpk1 inhibitors for the treatment of cancer

Номер патента: EP4373817A1. Автор: Li Sha,YE Wu,James Sheppeck,Jason Grant Kettle,Frederick Woolf Goldberg,Kun SONG,Dedong Wu,Tyler Grebe,Jason Shields,Neil Patrick Grimster,Robert Evans ZIEGLER,Kathryn Giblin,Amber Balazs,Randolph Escobar,Anthony Metrano,Adelphe Mfuh,Lucas Morrill,Sten NILSSON LILL. Владелец: AstraZeneca AB. Дата публикации: 2024-05-29.

N-(phenyl)-2-(phenyl)pyrimidine-4-carboxamide derivatives and related compounds as HPK1 inhibitors for treating cancer

Номер патента: AU2019223955B2. Автор: Qinda YE,Jun Pan,Alexander Sokolsky,Oleg VECHORKIN,Wenqing Yao,Evan STYDUHAR. Владелец: Incyte Corp. Дата публикации: 2024-06-13.

3-[(1h-pyrazol-4-yl)oxy]pyrazin-2-amine compounds as hpk1 inhibitor and use thereof

Номер патента: EP4222150A1. Автор: Jing Li,Zhiwei Wang,Sanjia Xu. Владелец: Beigene Ltd. Дата публикации: 2023-08-09.

3-[(1h-pyrazol-r-yl)oxy]pyrazin-2-amine compounds as hpk1 inhibitor and use thereof

Номер патента: US20240317714A1. Автор: Jing Li,Zhiwei Wang,Sanjia Xu. Владелец: Beigene Ltd. Дата публикации: 2024-09-26.

INDAZOLES AS HEMATOPOIETIC PROGENITOR KINASE 1 (HPK1) INHIBITORS AND METHODS USING SAME

Номер патента: US20220098219A1. Автор: Lee Jinhwa,Kim Jae Eun,JO Suyeon,LIM Keonseung,PARK A Yeong,GORAKSHNATH Gadhe Changdev,NAM Hwajung,JEON Yeonguk,HWANG Yejin,KIM Misoon,LIM Seung Mook. Владелец: . Дата публикации: 2022-03-31.

HPK1 INHIBITORS AND METHODS OF USING SAME

Номер патента: US20180179221A1. Автор: Liu Yong,Pauls Heinz W.,Laufer Radoslaw,Li Sze-Wan,Lang Yunhui,Patel Narendra Kumar B.,Ng Grace,Sampson Peter Brent. Владелец: . Дата публикации: 2018-06-28.

HPK1 INHIBITORS AND METHODS OF USING SAME

Номер патента: US20200190104A1. Автор: Liu Yong,Pauls Heinz W.,Laufer Radoslaw,Li Sze-Wan,Lang Yunhui,Patel Narendra Kumar B.,Ng Grace,Sampson Peter Brent. Владелец: . Дата публикации: 2020-06-18.

HPK1 INHIBITORS, PREPARATION METHOD AND APPLICATION THEREOF

Номер патента: US20210276994A1. Автор: LIAO Xuebin. Владелец: . Дата публикации: 2021-09-09.

ANILINOPYRIMIDINES AS HAEMATOPOIETIC PROGENITOR KINASE 1 (HPK1) INHIBITORS

Номер патента: US20190382379A1. Автор: Zhang Yun,Zhu Xiaotian,Huang Wei-Sheng,Youngsaye Willmen,Geno Erin. Владелец: . Дата публикации: 2019-12-19.

HPK1 inhibitors and methods of use thereof

Номер патента: CN107922431B. Автор: 刘勇,P·B·桑普森,N·K·B·帕特尔,H·W·鲍尔斯,李诗韵,G·恩格,R·劳弗,郎云辉. Владелец: UNIVERSITY HEALTH NETWORK. Дата публикации: 2021-06-04.

Isofuranone compounds useful as HPK1 inhibitors

Номер патента: ES2925450T3. Автор: Yan Chen,Erika M V Araujo,Bireshwar Dasgupta,Andrew P Degnan,Matthew D Hill,Godwin Kwame Kumi,Harold A Mastalerz,Mark D Wittman,Bradley C Pearce,Guifen Zhang. Владелец: Bristol Myers Squibb Co. Дата публикации: 2022-10-18.

Diazanaphthalenes as HPK1 inhibitors

Номер патента: CN110678466B. Автор: B·陈,魏斌清,梁军,胡永韩,陆爱军,J·德罗布尼克,M·肖,S·马尔霍特拉,A·马丁,胡百华,王炜如,E·甘西亚,G·琼斯,D·法沃,K·C·方,A·古德,C·斯蒂瓦拉,B·丹尼尔斯,L·加扎德,T·赫夫伦,M·赫斯特斯,R·门登卡,N·拉贾帕克萨,J·泰利斯,周爱和,M·W·卡特赖特,M·兰奇伯里,E·西沃德. Владелец: F Hoffmann La Roche AG. Дата публикации: 2023-01-31.

Hpk1 inhibitors and methods of using same

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