Inhibitors of brutonæs tyrosine kinase
Номер патента: SG166093A1
Опубликовано: 29-11-2010
Автор(ы): Erik Verner, Lee Honigberg, Zhengying Pan
Принадлежит: Pharmacyclics Inc
Опубликовано: 29-11-2010
Автор(ы): Erik Verner, Lee Honigberg, Zhengying Pan
Принадлежит: Pharmacyclics Inc
Реферат: Disclosed herein are compounds that form covalent bonds with Bruton's tyrosine kinase (Btk). Also described are irreversible inhibitors of Btk. Methods for the preparation of the compounds are disclosed. Also disclosed are pharmaceutical compositions that include the compounds. Methods of using the Btk inhibitors are disclosed, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, and inflammatory diseases or conditions. (no suitable figure)
Inhibitors of bruton's tyrosine kinase
Номер патента: ZA201100893B. Автор: Erik Verner,Lee Honigberg,Zhengying Pan. Владелец: Pharmacyclics Inc. Дата публикации: 2013-03-27.