Treatment of hepatic fibrosis with imatinib mesylate
Номер патента: EP1699461A4
Опубликовано: 06-05-2009
Автор(ы): Efsevia Albanis, Scott Friedman
Принадлежит: Mount Sinai School of Medicine
Опубликовано: 06-05-2009
Автор(ы): Efsevia Albanis, Scott Friedman
Принадлежит: Mount Sinai School of Medicine
Реферат: Disclosed herein is a method for treating hepatic fibrosis comprising administering to a patient in need of such treatment an amount effective to treat hepatic fibrosis of imatinib mesylate. This is based on the ability of imatinib mesylate to down regulate stellate cell activation in culture and in vivo. Hepatic fibrosis is not limited to patients with chronic Hepatitis B, Hepatitis C, non-alcoholic steatophepatitis (NASH), alcoholic liver disease, metabolic liver diseases (Wilson's disease, hemochromatosis), biliary obstruction (congenital or acquired) or liver diseases associated with fibrosis of unknown cause.
Treatment of hepatic fibrosis with imatinib mesylate
Номер патента: WO2005065690A1. Автор: Scott Friedman,Efsevia Albanis. Владелец: MOUNT SINAI SCHOOL OF MEDICINE OF NEW YORK UNIVERSITY. Дата публикации: 2005-07-21.