METHOD OF TREATING SCARS AND ß-CATENIN-MEDIATED DISORDERS USING NEFOPAM COMPOUNDS
Номер патента: EP2512468A1
Опубликовано: 24-10-2012
Автор(ы): Benjamin A. Alman, Helen Hong, Raymond Poon
Принадлежит: Hospital for Sick Children HSC
Опубликовано: 24-10-2012
Автор(ы): Benjamin A. Alman, Helen Hong, Raymond Poon
Принадлежит: Hospital for Sick Children HSC
Реферат: Methods of treating disorders mediated by β-catenin comprising administration of Nefopam compounds are provided In particular, the treatment of disorders arising from excessive or undesired expression of β- catenin is contemplated Said compounds include Nefopam, analogues thereof, prodaigs thereof, and salts and solvates of Nefopam The β-catenin mediated disorders are preferably selected from the group consisting of fibroproliferative disorders (such as scars, aggressive fibramtoses, and fibroses) and cancer (such as colon cancer, melanoma, liver cancer, ovarian cancer, endometrial cancer, medullobalstoma pilomatricomas, and prostate cancer)
METHODS AND FORMULATIONS FOR TREATING SCARS AND BETA-CATENIN-MEDIATED DISORDERS
Номер патента: US20170172980A1. Автор: Poon Raymond,Hong Helen,Alman Benjamin A.,Gauzer Gene. Владелец: . Дата публикации: 2017-06-22.