A biocompatible, non-biodegradable, non-toxic polymer useful for nanoparticle pharmaceutical compositions
Опубликовано: 30-04-2013
Автор(ы): Anand C Burman, GUPTA Pawan Kumar, Jaggi Manu, Khattar Dhiraj, Kumar Mukesh, Mukherjee Rama, Mullick Sanjoy, Praveen Rajendran, Prusthy Deepak, Singh Manoj Kumar, Singh Shobhit
Принадлежит: Fresenius Kabi Oncology Ltd
Реферат: THE INVENTION RELATES TO A BIOCOMPATIBLE, AND NON-TOXIC POLYMER OF FORMULA (I), COMPRISING OF THREE MONOMERIC UNITS, SELECTED FROM 1-VINYLPYRROLIDONE (VP), N-ISOPROPYLACRYLAMIDE (NIPAM), AND ESTER OF MALEIC ANHYDRIDE AND POLYETHYLENE GLYCOL (MPEG), CROSS-LINKED WITH A BI-FUNCTIONAL VINYL DERIVATIVE, OF HIGH PURITY AND SUBSTANTIALLY FREE OF RESPECTIVE TOXIC MONOMERIC CONTAMINANTS, AND A PROCESS FOR PREPARATION THEREOF. THE INVENTION FURTHER RELATES TO NANOPARTICULATE PHARMACEUTICAL COMPOSITIONS OF POORLY WATER-SOLUBLE DRUGS OR COMPOUNDS COMPRISING THE POLYMER OF THE INVENTION, WHICH ARE SAFE, LESS-TOXIC AND CONVENIENT FOR BEDSIDE ADMINSTRATION TO PATIENTS IN NEED THEREOF. FURTHERMORE, THE INVENTION RELATES TO A HIGHLY SELECTIVE METHOD FOR PREPARATION OF NANOPARTICULATE PHARMACEUTICAL COMPOSITIONS OF POORLY WATER-SOLUBLE DRUGS OR COMPOUNDS.
A biocompatible, non-biodegradable, non-toxic polymer useful for nanoparticle pharmaceutical compositions
Номер патента: CA2635469A1. Автор: Rajendran Praveen,Mukesh Kumar,Manoj Kumar Singh,Dhiraj Khattar,Rama Mukherjee,Anand C. Burman,Manu Jaggi,Sanjoy Mullick,Pawan Kumar Gupta,Shobhit Singh,Deepak Prusthy. Владелец: Individual. Дата публикации: 2007-07-05.