Methods of using 4-amino-n-[4-(methoxymethyl)phenyl]-7-(1-methylcyclopropyl)-6-(3-morpholinoprop-1-yn-1-yl)-7h-pyrrolo[2,3-d]pyrimidine-5-carboxamide for the treatment of tumors
Номер патента: CA3201329A1
Опубликовано: 27-05-2022
Автор(ы): Alberto Bernareggi, Annalisa Bonifacio, Claudio Giuliano, Emanuela Lovati, Isao Miyazaki, Masanori Kato, Miharu Igarashi, Ruben GIORGINO, Simona Doria
Принадлежит: HELSINN HEALTHCARE SA, Taiho Pharmaceutical Co Ltd
Опубликовано: 27-05-2022
Автор(ы): Alberto Bernareggi, Annalisa Bonifacio, Claudio Giuliano, Emanuela Lovati, Isao Miyazaki, Masanori Kato, Miharu Igarashi, Ruben GIORGINO, Simona Doria
Принадлежит: HELSINN HEALTHCARE SA, Taiho Pharmaceutical Co Ltd
Реферат: The present invention relates to compositions and methods for treating patients with cancer having a RET gene abnormality comprising administering HM06/TAS0953, for example patients with non-small cell lung cancer (NSCLC), and that may also have brain and/or leptomeningeal metastases, or another solid tumor; where the patient is administered an effective amount of HM06/TAS0953, where the HM06/TAS0953 can be formulated in a composition and administered orally in a single or multiple doses; and where the patients may have previously received and/or have developed resistance to another RET-selective or multi-kinase inhibitor.
Methods of using 4-amino-n-[4-(methoxymethyl)phenyl]-7-(1-methylcyclopropyl)-6-(3-morpholinoprop-1-yn-1-yl)-7h-pyrrolo[2,3-d]pyrimidine-5-carboxamide for the treatment of tumors
Номер патента: EP4247379A1. Автор: Claudio Giuliano,Masanori Kato,Isao Miyazaki,Alberto Bernareggi,Ruben GIORGINO,Emanuela Lovati,Simona Doria,Annalisa Bonifacio,Miharu Igarashi. Владелец: Taiho Pharmaceutical Co Ltd. Дата публикации: 2023-09-27.