Synthesis of vinyl cyclobutyl intermediates
Номер патента: EP4146634A1
Опубликовано: 15-03-2023
Автор(ы): Austin G. Smith, Gabrielle St-Pierre, Kyle D. BAUCOM, Michael T. CORBETT, Neil Fred Langille, Peter K. Dornan, Philipp C. ROOSEN, Roberto Profeta, Sheng Cui
Принадлежит: AMGEN INC
Опубликовано: 15-03-2023
Автор(ы): Austin G. Smith, Gabrielle St-Pierre, Kyle D. BAUCOM, Michael T. CORBETT, Neil Fred Langille, Peter K. Dornan, Philipp C. ROOSEN, Roberto Profeta, Sheng Cui
Принадлежит: AMGEN INC
Реферат: Provided herein are processes for synthesizing intermediates useful in preparing Mcl-1 inhibitors. In particular, provided herein are processes for synthesizing compound F, or a salt thereof, wherein R1 and OPG2 are described herein. Compound F can be useful in synthesizing compound A1, or a salt of solvate thereof, and compound A2, or a salt of solvate thereof.
Method for combined synthesis of urea and melamine
Номер патента: RU2446153C2. Автор: Федерико ЗАРДИ,Паоло БРУНЕНГО,Паоло СТИККИ. Владелец: Уреа Касале С.А.. Дата публикации: 2012-03-27.