Peptides derived from the attachment (g) protein of respiratory syncytial virus
Номер патента: EP1015595A1
Опубликовано: 05-07-2000
Автор(ы): Gerald E. Hancock, Paul W. Tebbey
Принадлежит: American Cyanamid Co
Опубликовано: 05-07-2000
Автор(ы): Gerald E. Hancock, Paul W. Tebbey
Принадлежит: American Cyanamid Co
Реферат: An altered G protein or portion thereof of RSV which retains immunogenicity and which, when incorporated into an immunogenic composition or vaccine and administered to a vertebrate, does not induce enhanced disease (e.g., atypical pulmonary inflammation such as pulmonary eosinophilia) upon subsequent infection with RSV, is disclosed. In a particular embodiment, the altered G protein comprises an alteration in the region from amino acid 184 to amino acid 198. Immunogenic compositions and vaccines comprising the altered RSV G protein, and optionally comprising RSV F protein, are also disclosed.
Plant-derived vaccines against respiratory syncytial virus
Номер патента: US20110076302A1. Автор: Schuyler S. Korban,Jagdeep Sandhu,Dennis E. Buetow,Sergei F. Krasnyanski. Владелец: Individual. Дата публикации: 2011-03-31.