环肽类抗肿瘤活性化合物及其制备方法与应用.

环肽类抗肿瘤活性化合物及其制备方法与应用

Номер патента: CN112778403B
Опубликовано: 19-08-2022
Автор(ы): 丛薇, 何世鹏, 刘婧, 李英华, 汤华, 胡宏岗, 高飞
Принадлежит: UNIVERSITY OF SHANGHAI FOR SCIENCE AND TECHNOLOGY
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Рисунок 1. Взаимосвязь патентов (ближайшие 20).

Cyclic peptide antitumor agents

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Cyclic peptide antitumor agents

Номер патента: US20050159346A1. Автор: Thomas Adrian,Gerald Soff,Wenxin Gu,Richard Silverman,Shouxin Liu. Владелец: Individual. Дата публикации: 2005-07-21.

Cyclic peptide antitumor agents

Номер патента: US7709443B2. Автор: Wenxin Gu,Richard B. Silverman,Thomas E. Adrian,Gerald A. Soff,Shouxin Liu. Владелец: Northwestern University. Дата публикации: 2010-05-04.

Cell-permeable cyclic peptides and uses thereof

Номер патента: WO2022251372A1. Автор: Cameron PYE,Joshua SCHWOCHERT,Anthony Silvestri. Владелец: Unnatural Products Inc.. Дата публикации: 2022-12-01.

New cyclic peptide compounds

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Cyclic peptide dimers

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Synthetic cyclic peptide mimetics

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Synthetic cyclic peptide mimetics

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Cell-permeable cyclic peptides and uses thereof

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Cell-permeable cyclic peptides and uses thereof

Номер патента: EP4351620A1. Автор: Cameron PYE,Joshua SCHWOCHERT,Anthony Silvestri. Владелец: Unnatural Products Inc. Дата публикации: 2024-04-17.

Cell-permeable cyclic peptides and uses thereof

Номер патента: US20240199702A1. Автор: Cameron PYE,Joshua SCHWOCHERT,Anthony Silvestri. Владелец: Unnatural Products Inc. Дата публикации: 2024-06-20.

Designer cyclic peptides—HIV gp120 antagonists and their applications

Номер патента: US8361969B2. Автор: Przemyslaw Czyryca. Владелец: Individual. Дата публикации: 2013-01-29.

Designer Cyclic Peptides - HIV gp120 Antagonists and their Applications

Номер патента: US20120270806A1. Автор: Przemyslaw Czyryca. Владелец: Individual. Дата публикации: 2012-10-25.

Cyclic peptides, methods of synthesis, and methods of treatment

Номер патента: US11753447B2. Автор: Adam G. Kreutzer,James S. Nowick. Владелец: UNIVERSITY OF CALIFORNIA. Дата публикации: 2023-09-12.

Synthetic cyclic peptide mimetics

Номер патента: US20240316225A1. Автор: Brigitte Guerin,William Lubell,Pradeep Chauhan,Samia Ait-Mohand,Ramesh Chingle,Maram HABASHI,Michal RICHMAN,Suresh VUTLA,Veronique DUMULON-PERREAULT,Shai RAHIMPOUR. Владелец: Societe de Commercialisation des Produits de la Recherche Appliquee SOCPRA. Дата публикации: 2024-09-26.

Novel cyclic peptide compounds

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A cyclic peptide and pharmaceutical composition comprising the same for inhibiting proliferation of hev

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Cyclic peptide compound or pharmacologically acceptable salt thereof and method for producing same

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Номер патента: EP4378937A1. Автор: Qiang Zhang. Владелец: Shanghai Allist Pharmaceuticals Inc. Дата публикации: 2024-06-05.

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Номер патента: MY200925A. Автор: Wei Zheng,Chen Zhang,Fei Ye,Jianmin Wang,Longbin HUANG,Zhenggang HUANG,Pangke Yan,Yonggang Wei,Anbang HUANG. Владелец: Sichuan Haisco Pharmaceutical Co Ltd. Дата публикации: 2024-01-24.

GLP-1 agonist polypeptide compound and salt thereof, and synthesis method and application thereof

Номер патента: CN111253475B. Автор: 施国强,王蔡典,赵呈青,李顺子. Владелец: Hangzhou Sinopep Aosainuo Pharmaceutical Technology Development Co ltd. Дата публикации: 2021-03-09.

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Номер патента: CN113307785B. Автор: 许明峰,朱芹,田霖丹,戴杨帆. Владелец: Hangzhou Normal University. Дата публикации: 2022-09-23.

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Butylphthalide-telmisartan heterocomplex, preparation method and application thereof

Номер патента: US20190375729A1. Автор: Cunfang Wang,Tao Pang,Zhangjian HUANG,Wenbin ZENG,Jinxiang DENG,Weijie WU,Tingyu Huang. Владелец: Guangdong Longfu Medicine Co ltd. Дата публикации: 2019-12-12.

Quinazoline compound, and preparation method therefor and application thereof

Номер патента: US20240262793A1. Автор: Fei Zhao,Guangxin Xia,Gongsheng LI,Yuji Wang,Ying KE,Yichen Wu,Lijun Hao,Lisha DU. Владелец: Shanghai Pharmaceuticals Holding Co Ltd. Дата публикации: 2024-08-08.

Butylphthalide-telmisartan heterocomplex, preparation method and application thereof

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Номер патента: AU2020327501A1. Автор: Liang Ye,Rui Zhang,Bo Cui,Dawei Yu,Jingwei Tian,Guangying DU,Zongliang LIU,Fangxia ZOU. Владелец: Geneora Pharma Shijiazhuang Co Ltd. Дата публикации: 2022-02-24.

Dendritic polyethylene glycol derivative, and preparation method and application thereof

Номер патента: US20200131107A1. Автор: Hui Zhu,Xuan Zhao,Meina Lin. Владелец: Tianjin Jenkem Technology Co Ltd. Дата публикации: 2020-04-30.

Small-molecule compound SPAM1 for up-regulating neuropeptide PACAP and receptor PAC1-R thereof, and preparation method therefor and application thereof

Номер патента: AU2020447435B2. Автор: Rongjie Yu. Владелец: Chen Jianhuan. Дата публикации: 2022-12-01.

Regulator containing tricyclic derivative, preparation method therefor and application thereof

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Biflavone-iron complex, preparation method and application thereof

Номер патента: US20200239506A1. Автор: LI Xu,Shilong Yang,Fuliang CAO. Владелец: NANJING FORESTRY UNIVERSITY. Дата публикации: 2020-07-30.

Ox40-targeted antibody, and preparation method therefor and application thereof

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Small-molecule compound SPAM1 for up-regulating neuropeptide PACAP and receptor PAC1-R thereof, and preparation method therefor and application thereof

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Cyclic dinucleotide metal compound, and preparation and application thereof

Номер патента: US20240317792A1. Автор: Xiangshi TAN,Daofeng XIANG,Yingxuan TAN. Владелец: Hangzhou Xingao Biotechnology Co Ltd. Дата публикации: 2024-09-26.

Berberine salts, ursodeoxycholic salts and combinations, methods of preparation and application thereof

Номер патента: US20230295151A1. Автор: Liping Liu. Владелец: Shenzhen Hightide Biopharmaceutical Ltd. Дата публикации: 2023-09-21.

Preparation and application of triterpenoids with effect of improving glucose and lipid metabolism disorders

Номер патента: US20230022783A1. Автор: Yan Zhang,Ping Li,XiaoJun Tang,Pengfei Zhou,Guang Liu,Mingwei Zhang,Zhihao ZHAO,Xuchao JIA,Zhencheng Wei,Yunayuan Deng. Владелец: Sericultural&agri Food Research Institute Guangdong Academy Of Agricultural Sciences. Дата публикации: 2023-01-26.

Anti-dll3 antibody and preparation method therefor, drug conjugate and application thereof

Номер патента: EP4378955A1. Автор: Tong Yang,Fang Wu,Wenbo Zhang,Baoxia Wang,Yijun Shen,Qingsong GUO,Bei Gao,Likai MENG. Владелец: Shanghai Fudan Zhangjiang Bio pharmaceutical Co Ltd. Дата публикации: 2024-06-05.

2-(aryl-2-yl) morpholine and deuterated derivative thereof, preparation method therefor and application thereof

Номер патента: EP4428128A1. Автор: Wensheng Yu,Yidong Su,Zhiqiang Huang,Haining DENG,Kailong Li,Xiaohan Zhou. Владелец: Shanghai Hansoh Biomedical Co Ltd. Дата публикации: 2024-09-11.

RORyT MODULATOR, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF

Номер патента: US20240317686A1. Автор: Chen Shi,Tao Liang,Qian Wang,Guangxin Xia,Yongxin Zhao,Guosheng Wu,Ying KE,Zhijun Xiang,Bingbin ZHANG,Sijie Shu,Guoyong HUO,Lingwen Li. Владелец: Shanghai Pharmaceuticals Holding Co Ltd. Дата публикации: 2024-09-26.

Benzimidazole derivatives and application thereof for gamma-amino-butyric acid (gabaa) receptor complex modulation

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2,6-dioxaspiro [4,5] decane derivatives and preparation method therefor and pharmaceutical applications thereof

Номер патента: US20200255444A1. Автор: Yang Zhang,JIAN Li,Jie Li,Shuhui Chen,Zhixiang Li,Jikui Sun,Wentao Wu,Guangwen Yang. Владелец: Shandong Luye Pharmaceutical Co Ltd. Дата публикации: 2020-08-13.

Quinolinamine compound, preparation method therefor and application thereof in pharmaceuticals

Номер патента: US20240327388A1. Автор: FENG He,Fanglong Yang,Weikang Tao,Minqiang JIA,Huanyu TANG,Yonglei QUE. Владелец: Jiangsu Hengrui Pharmaceutical Co Ltd. Дата публикации: 2024-10-03.

Cycloalkene derivative regulator, preparation method therefor, and application thereof

Номер патента: US20240360109A1. Автор: Jun Wang,Wensheng Yu,Yidong Su,Xiaofeng MAO,Xiaohan Zhou. Владелец: Shanghai Hansoh Biomedical Co Ltd. Дата публикации: 2024-10-31.

Multi-functional composition and preparation method and application thereof

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Isoquinoline compound, manufacturing method therefor, and application thereof

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Multifunctional immunity-targeted micromolecule anti-cancer medicine Bestazomib (Bestazomib) and preparation method and application thereof

Номер патента: US12054502B2. Автор: Jian Zhang,Zhen Zhang,Xiaoyang Li,Xiaobo Xu,Wenfang Xu,Yuqi JIANG,Leqiao TAN,Yongxue HUANG,Xuejian WANG. Владелец: Shandong Hubble Kisen Biological Technonlogy Co Ltd. Дата публикации: 2024-08-06.

RTN4B polypeptide, monoclonal antibody thereof, monoclonal antibody-producing hybridoma cell strain, and, preparation and application thereof

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Rtn4b polypeptide, monoclonal antibody thereof, monoclonal antibody-producing hybridoma cell strain, and, preparation and application thereof

Номер патента: US20150125885A1. Автор: Long Yu,Yanhua Wu,Lisha Tang,Guoqing Ji,Dingding Han. Владелец: FUDAN UNIVERSITY. Дата публикации: 2015-05-07.

Fused tetracyclic compound, preparation method therefor and application thereof in medicine

Номер патента: US20240327434A1. Автор: FENG He,Yang Chen,Feng Shen,Xin Li,Weikang Tao,Huaide DONG. Владелец: Jiangsu Hengrui Pharmaceutical Co Ltd. Дата публикации: 2024-10-03.

Imidazotriazine thiobenzamide derivative, and preparation method and application thereof

Номер патента: US20240294535A1. Автор: Xinyi Wang,Zhengwu Shen,Bin Deng,Xuejiang Chen,Yunxiang Fan,Yangli SHEN,Yinshuang WU,Hongzhu BIAN. Владелец: Yunbaiyao Zhengwu Science And Technology (shanghai) Co Ltd. Дата публикации: 2024-09-05.

1-phenyl propanone compounds and application thereof

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Substituted benzo or pyridopyrimidine amine inhibitor, preparation method therefor, and application thereof

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Substituted benzo or pyridopyrimidine amine inhibitor, preparation method therefor, and application thereof

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Beta-lactamase inhibitors and application thereof

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Pyrimidine-fused cyclic compound and preparation method and use thereof

Номер патента: EP4397664A1. Автор: Tao Jiang,Tao Liang,Kai Ma,Qi Huang,Jiong Lan,Jichen Zhao,Xiaoming Xu,Fusheng ZHOU,Leitao ZHANG,Lijian CAI,Chonglan LIN,Zhubo LIU,Yandong LU. Владелец: Zhejiang Genfleet Therapeutics Co Ltd. Дата публикации: 2024-07-10.

Pyrido[2,3-d]pyrimidine HIV-1 reverse transcriptase inhibitor, preparation method therefor and application thereof

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Terpineol and preparation method and application thereof

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Terpineol and preparation method and application thereof

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Sos1 degrading agent and preparation method therefor and application thereof

Номер патента: US20240261418A1. Автор: Yan Feng,Hong Wei,Qiao WANG,Zhengqing YE,Chenli Ding,Shiqiang Li,Shuchen XIE. Владелец: Shanghai Leadingtac Pharmaceutical Co Ltd. Дата публикации: 2024-08-08.

Sos1 degrading agent and preparation method therefor and application thereof

Номер патента: US20240261417A1. Автор: Yan Feng,Hong Wei,Qiao WANG,Zhengqing YE,Chenli Ding,Shiqiang Li,Shuchen XIE. Владелец: Shanghai Leadingtac Pharmaceutical Co Ltd. Дата публикации: 2024-08-08.

Salt of selective fgfr4 inhibitor, and preparation method therefor and application thereof

Номер патента: US20240287044A1. Автор: Yi Li,Lei Chen,Jinqing Zhong,Yongxiang Gong,Xiaohe Zheng,Xinlong Zhang,Lifei MAO. Владелец: Zhejiang Hisun Pharmaceutical Co Ltd. Дата публикации: 2024-08-29.

Abiraterone derivative, preparation and application thereof

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Fused heterocyclic compound and application thereof, pharmaceutical compositions containing same and application thereof

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Abiraterone derivative and preparation and application thereof

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Salt form of pyrrolotriazine compound, crystal form thereof, and preparation method therefor

Номер патента: US20240254144A1. Автор: Ning Jiang,XU You,Xiongbin Xu,Shuhui Chen,Lingyun Wu,Xiawei WEI. Владелец: Jumbo Drug Bank Co Ltd. Дата публикации: 2024-08-01.

Pyrimidines applicable as anti-infectious agents, and applications thereof

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Halogen-substituted phenylate compound and applications thereof

Номер патента: AU2020334850A1. Автор: Yu Li,Haibo Li,Yuanwei Chen,Xinghai Li,Chengzhi Zhang,Wu Du. Владелец: Hinova Pharmaceuticals Inc. Дата публикации: 2022-03-10.

Salt form of pyrrolotriazine compound, crystal form thereof, and preparation method therefor

Номер патента: ZA202310368B. Автор: Ning Jiang,XU You,Xiongbin Xu,Shuhui Chen,Lingyun Wu,Xiawei WEI. Владелец: Jumbo Drug Bank Co Ltd. Дата публикации: 2024-05-30.

7-ethyl-10-hydroxycamptothecin drug precursor with fluorescence activity, and preparation method and use thereof

Номер патента: US20240156990A1. Автор: Han Xu,Hui He,Zhengqing GUO,Yangyang Huang,Dandan Ji,Dingding AI. Владелец: SUZHOU UNIVERSITY. Дата публикации: 2024-05-16.

Small molecule compounds having naphthylamine structure and application thereof

Номер патента: US20240254078A1. Автор: Dong Liu,Xiaoyan Xu,Zhen Tian,Mengyang FAN,Hongguang XIA,Xufeng CEN,Ronghai WU. Владелец: Hangzhou Phecdamed Co Ltd. Дата публикации: 2024-08-01.

Small molecule compounds having naphthylamine structure and application thereof

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Bicyclic compound and application thereof

Номер патента: EP4428125A1. Автор: Jian Zhang,Yun Sun,Yu Wang,Teng MA,Pingping Wang,Lieming Ding,Jiabing Wang,Hong LAN,Rongwen YANG,Xuegang YI. Владелец: Betta Pharmaceuticals Co Ltd. Дата публикации: 2024-09-11.

Small molecule compounds having naphthylamine structure and application thereof

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Cyclic peptides for targeting epidermal growth factor receptor and mutations thereof for drug delivery

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Pyrrolopyrimidine compounds and application thereof

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Salt of benzothiopyrone compound, and preparation method therefor and application thereof

Номер патента: ZA202203673B. Автор: Yan Li,Peng Li,Gang Li,Tingting ZHANG,Chen Ma,Haihong Huang,Baolian Wang. Владелец: Inst Materia Medica Cams. Дата публикации: 2024-01-31.

Selective parp1 inhibitor and application thereof

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Selective parp1 inhibitor and application thereof

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Pyrrolopyrazole derivatives, preparation method thereof and application thereof in medicine

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New [2-(dimethylamino)-2-phenylbutyl]-3,4,5-trimetoxybenzoate 4-methyl-2h-chromen-2-on-7-ilsulphate compound and application thereof

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Cyano-substituted pyridine and cyano-substituted pyrimidine compound and preparation method therefor and application thereof

Номер патента: EP4083021A1. Автор: Qiang Zhang,Yueming SUN,Leifu YANG,Shannan YU,Nanqiao ZHENG,Zhenke GUO. Владелец: Beijing Scitech MQ Pharmaceuticals Ltd. Дата публикации: 2022-11-02.

Cyano-substituted pyridine and cyano-substituted pyrimidine compound and preparation method therefor and application thereof

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Bicyclic heterocyclic fgfr4 inhibitor, pharmaceutical composition and preparation comprising same, and application thereof

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Lappaconitine derivative with analgesic activity, and preparation and application thereof

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Camptothecin compound, preparation method therefor, and application thereof

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Camptothecin compound, preparation method therefor, and application thereof

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Camptothecin compound, preparation method therefor, and application thereof

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Truncated evans blue modified fibroblast activation protein inhibitor, preparation method and application thereof

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Preparation method and application of sesquiterpenes and their dimers

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Heterocyclic compound and application thereof in medicine

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Truncated evans blue modified fibroblast activation protein inhibitor, preparation method and application thereof

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Selective parp1 inhibitor and application thereof

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Human Type 14 Replication Defective Adenovirus Vector and Preparation Method for Same and Applications Thereof

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Five-membered ring-substituted pyridazinol compounds and derivatives, preparation methods, herbicidal compositions and applications thereof

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