Substituerede 1,4-dihydropyridinlactoner, fremgangsmaader til deres fremstilling og deres anvendelse som laegemidler.

Substituerede 1,4-dihydropyridinlactoner, fremgangsmaader til deres fremstilling og deres anvendelse som laegemidler

Номер патента: DK144984A
Опубликовано: 26-09-1984
Автор(ы): Friedrich Bossert, Guenter Thomas, Matthias Schramm, Rainer Gross, SIEGFRIED Goldmann
Принадлежит: Bayer AG
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Рисунок 1. Взаимосвязь патентов (ближайшие 20).

Circulation-active novel chromone- and thiochromone-substituted 1,4-dihydropyridine-lactones

Номер патента: US4555512A. Автор: SIEGFRIED Goldmann,GUNTER Thomas,Friedrich Bossert,Matthias Schramm,Rainer Gross. Владелец: Bayer AG. Дата публикации: 1985-11-26.

SUBSTITUTED 1,4-DIHYDROPYRIDIN LACTONES, PROCEDURES FOR THEIR PREPARATION AND THEIR USE AS MEDICINES

Номер патента: DK144984D0. Автор: SIEGFRIED Goldmann,Guenter Thomas,Friedrich Bossert,Matthias Schramm,Rainer Gross. Владелец: Bayer AG. Дата публикации: 1984-02-29.

CHROMON AND THIOCHROMONE SUBSTITUTED 1,4-DIHYDROPYRIDIN LACTONE, SEVERAL PROCESSES FOR THEIR PRODUCTION AND THEIR USE IN MEDICINAL PRODUCTS

Номер патента: DE3311003A1. Автор: Günter Dr. Thomas,Friedrich Dipl.-Chem. Dr. 5600 Wuppertal Bossert,Siegfried Dipl.-Chem. Dr. Goldmann,Rainer Dr. 5600 Wuppertal Groß,Matthias Dr. 5000 Köln Schramm. Владелец: Bayer AG. Дата публикации: 1984-09-27.

CHROMON- AND TIOCHROMON-SUBSTITUTED 1,4-DIHYDROPYRIDINE LACTATES, MORE PROCEDURES FOR THEIR PREPARATION AND THEIR USE IN PHARMACEUTICALS

Номер патента: NO840950L. Автор: SIEGFRIED Goldmann,Friedrich Bossert,Matthias Schramm,Rainer Gross,Thomas Guent. Владелец: Bayer AG. Дата публикации: 1984-09-26.

Chromone-and thiochromone-substituted 1,4-dihydropyridine-lactones,their preparation and pharmaceutical compositions containing them

Номер патента: IL71314A0. Автор: . Владелец: Bayer AG. Дата публикации: 1984-06-29.

Chromone-substituted and thiochromone-substituted 1, 4-dihydropyridine-lactones, manufacture and use

Номер патента: JPS59193887A. Автор: マテイアス・シユラム,ジ−クフリ−ト・ゴルトマン,フリ−ドリツヒ・ボツセルト,ギユンタ−・ト−マス,ライナ−・グロ−ス. Владелец: Bayer AG. Дата публикации: 1984-11-02.

Chromone- and thiochromone-substited 1,4-dihydropyridine lactones, processes for their preparation and their use as pharmaceutical preparations

Номер патента: EP0123095A3. Автор: Siegfried Dr. Goldmann,Friedrich Dr. Bossert,Matthias Dr. Schramm,Günter Dr. Thomas,Rainer Dr. Gross. Владелец: Bayer AG. Дата публикации: 1986-12-03.

Chromone- and thiochromone-substited 1,4-dihydropyridine lactones, processes for their preparation and their use as pharmaceutical preparations

Номер патента: DE3474824D1. Автор: Siegfried Dr Goldmann,Friedrich Dr Bossert,Matthias Dr Schramm,Rainer Dr Gross,Gunter Dr Thomas. Владелец: Bayer AG. Дата публикации: 1988-12-01.

Chromone- and thiochromone-substited 1,4-dihydropyridine lactones, processes for their preparation and their use as pharmaceutical preparations.

Номер патента: ES8707958A1. Автор: . Владелец: Bayer AG. Дата публикации: 1987-09-01.

Chromone- and thiochromone-substited 1,4-dihydropyridine lactones, processes for their preparation and their use as pharmaceutical preparations.

Номер патента: ES8707959A1. Автор: . Владелец: Bayer AG. Дата публикации: 1987-09-01.

Chromone- and thiochromone-substited 1,4-dihydropyridine lactones, processes for their preparation and their use as pharmaceutical preparations.

Номер патента: ES8707957A1. Автор: . Владелец: Bayer AG. Дата публикации: 1987-09-01.

Chromone- and thiochromone-substited 1,4-dihydropyridine lactones, processes for their preparation and their use as pharmaceutical preparations

Номер патента: EP0123095A2. Автор: Siegfried Dr. Goldmann,Friedrich Dr. Bossert,Matthias Dr. Schramm,Günter Dr. Thomas,Rainer Dr. Gross. Владелец: Bayer AG. Дата публикации: 1984-10-31.

Chromone- and thiochromone-substited 1,4-dihydropyridine lactones, processes for their preparation and their use as pharmaceutical preparations.

Номер патента: ES8607307A1. Автор: . Владелец: Bayer AG. Дата публикации: 1986-06-16.

Chromone- and thiochromone-substited 1,4-dihydropyridine lactones, processes for their preparation and their use as pharmaceutical preparations.

Номер патента: ES8707952A1. Автор: . Владелец: Bayer AG. Дата публикации: 1987-09-01.

Process for producing 1,4-dihydropyridine-lactone derivatives substituted with chromone - and thiochromone-groups

Номер патента: HU189849B. Автор: SIEGFRIED Goldmann,Guenter Thomas,Friedrich Bossert,Matthias Schramm,Rainer Gross. Владелец: Bayer Ag,De. Дата публикации: 1986-08-28.

Sila-substituted 1,4-dihydropyridine derivatives, processes for their preparation, pharmaceutical compositions and process for their preparation

Номер патента: EP0010130B1. Автор: Robertson Dr. Towart,Wulf Dr. Vater,Reinhold Dr. Tacke,Anke Bentlage. Владелец: Bayer AG. Дата публикации: 1981-12-23.

Sila-substituted 1,4-dihydropyridine derivatives their production and pharmaceutical compositions containing them

Номер патента: IL58103A0. Автор: . Владелец: Bayer AG. Дата публикации: 1979-12-30.

Nitro-substituted 1,4-dihydropyridines, processes for _their production and their medicinal use

Номер патента: US4248873A. Автор: Gerhard Franckowiak,Horst Meyer,Stanislav Kazda,Friedrich Bossert,Egbert Wehinger,Robertson Towart,Arend Heise,Kurt Stoepel. Владелец: Bayer AG. Дата публикации: 1981-02-03.

N-substituted-tetrahydrothiazines, process for their preparation, and their use as pesticides

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1-ALKYL-SUBSTITUTED 1,4-DIHYDROPYRIDINE LACTONES AND THEIR USE IN PHARMACEUTICALS

Номер патента: DK158517C. Автор: SIEGFRIED Goldmann,Hilmar Bischoff,Dieter Petzinna,Walter Puls,Friedrich Bossert,Klaus Schlossmann. Владелец: Bayer AG. Дата публикации: 1990-11-05.

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Imidazolyl and pyridyl derivatives of phenyl substituted 1,4-dihydropyridines and process for their preparation

Номер патента: US5514693A. Автор: Patricia Salvati,Paolo Cozzi,Germano Carganico,Mariia Menichincheri. Владелец: Farmitalia Carlo Erba SRL. Дата публикации: 1996-05-07.

2-substituted 1,4-dihydropyridine derivatives

Номер патента: GB2196631A. Автор: Kiyoshi Kimura,Toshio Tomita,Masahiro Kise,Masami Tsuda,Iwao Morito. Владелец: Nippon Shinyaku Co Ltd. Дата публикации: 1988-05-05.

2-substituted 1,4-dihydropyridine derivative

Номер патента: JPS63115890A. Автор: Kiyoshi Kimura,Iwao Morita,Toshio Tomita,Masahiro Kise,Masami Tsuda,木村　喜代史,森田　岩男,黄瀬　正博,冨田　敏夫,正己津田. Владелец: Nippon Shinyaku Co Ltd. Дата публикации: 1988-05-20.

Trifluoromethyl-phenoxy-phenyl-silicon derivatives, processes for their preparation, and their use as herbicides and plant-growth regulators

Номер патента: US4481365A. Автор: Robert Schmidt,Klaus Lurssen,Ludwig Eue,Heinz Forster. Владелец: Bayer AG. Дата публикации: 1984-11-06.

Trifluoromethyl-phenoxy-phenyl-silicon derivatives, processes for their preparation, and their use as herbicides and plant-growth regulators

Номер патента: CA1179337A. Автор: Robert Schmidt,Klaus Lurssen,Ludwig Eue,Heinz Forster. Владелец: Bayer AG. Дата публикации: 1984-12-11.

Chromone- and thiochromone-substituted 1,4- dihydropyridine derivatives, several processes for their preparation and their use in medicaments

Номер патента: CA1236460A. Автор: SIEGFRIED Goldmann,Gerhard Franckowiak,GUNTER Thomas,Matthias Schramm,Rainer Gross. Владелец: Bayer AG. Дата публикации: 1988-05-10.

Substituted 1,4-dihydropyridines, method for their preparation and their use as pharmaceuticals

Номер патента: EP0116708A1. Автор: Melitta Dr. Just,Karl Dr. Schönafinger,Helmut Dr. Bohn,Piero Dr. Martorana. Владелец: Cassella Farbwerke Mainkur AG. Дата публикации: 1984-08-29.

Chromone- and thiochromone-substituted 1,4-dihydropyridines, processes for their preparation and their use in pharmaceutical preparations

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2-substituted-1,4-dihydropyridines,method for their preparation and pharmaceutical compositions containing them

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New highly selective process for the preparation of enantiomerically pure phenyl-substituted 1, 4- dihydropyridine-3,5-dicarboxylic acid derivatives

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Furopyridinyl-substituted 1,4-dihydropyridine derivatives and methods of use thereof

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Pharmaceutical compositions containing phenyl-substituted 1,4-dihydropyridines certain such novel compounds and their preparation

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SUBSTITUTED 1,4-DIHYDROPYRIDIN-3-CARBONIC ACID PIPERAZIDES, METHOD FOR THE PRODUCTION AND THEIR USE IN MEDICINAL PRODUCTS

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PROCEDURE FOR THE PREPARATION OF ENANTIOMERALLY PURE POLICY SUBSTITUTED 1,4-DIHYDROPYRIDINES.

Номер патента: NO913188D0. Автор: Marco Frigerio,Andrea Zaliani,Roberto Di Domenico,Carlo Riva,Giorgio Long,Carmelo A Gandolfi. Владелец: Boehringer Mannheim Italia. Дата публикации: 1991-08-15.

4-Phenyl-3-substituted 1,4-dihydropyridine esters with cerebral activity

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A PROCEDURE FOR THE PREPARATION OF ENANTIOMERALLY PURE POLY-SUBSTITUTED 1,4-DIHYDROPYRIDINES.

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Method for synthesis of symmetric ester of 4-substituted 1,4-dihydropyridine-3,5-dicarboxylic acid or its physiologically acceptable salt

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PROCEDURES FOR THE PREPARATION OF SUBSTITUTED 1,4-DIHYDROPYRIDINES

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FUROPYRIDINYL-SUBSTITUTED 1,4-DIHYDROPYRIDINE DERIVATIVES AND METHODS OF USE THEREOF

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5-Membered heteroaryl substituted 1,4-dihydropyridine compounds as bradykinin antagonists

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Method of producing substituted 1,4-dihydropyridines

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Process for preparing methionine-substituted 1,4-dihydropyridines

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Method of new substituted 1,4-dihydropyridines production

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New highly selective process for the preparation of enantiomerically pure phenyl-substituted 1,4- dihydropyridine-3, 5-dicarboxylic acid derivatives

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Unsymmetrical esters of N-substituted 1,4-dihydropyridine 3,5-dicarboxylic acid

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Antibodies comprising site-specific non-natural amino acid residues, methods of their preparation and methods of their use

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Phenothiazines and their derivatives for use as a medicament

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1h-furo[3,2-c]pyrazole compounds useful as kinase inhibitors

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Preparation and Uses of 7-Azaindenoisoquinolines

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camptothecin derivatives, process for their preparation, pharmaceutical composition and their use

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Polyazamacrocyclofluoromonoalkylphosphonic acids, and their complexes, for use as contrast agents

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Derivatives of 3-(guanidinocarbonyl) heterocycle, methods of preparation and intermediates thereof, their use as medicaments, and pharmaceutical compositions therefrom

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Polyisocyanates containing allophanate and isocyanurate groups, a process for their production from cyclic diisocyanates and their use in two-component coating compositions

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Diamino alcohols and their use as renin inhibitor

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Benzimidazoyl glp-1 receptor agonists, pharmaceutical compositions comprising the same, and methods for their use

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Gpcr receptor agonists, pharmaceutical compositions comprising the same, and methods for their use

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Novel atp-sensitive potassium channel potentiators, their preparation and use

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Gpcr receptor agonists, pharmaceutical compositions comprising the same, and methods for their use

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Gpcr receptor agonists, pharmaceutical compositions comprising the same, and methods for their use

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Aminoalkyl-imidazothiadiazole-alkenecarboxylic acid amides, intermediates for their preparation and their use in medicaments

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Indane derivatives, process for their preparation and intermediates obtained, their use as medicines, and pharmaceutical compositions containing them

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Substituted 1-aminoalkylamino-4-aryloxypiperidines a process for their preparation intermediates thereof and their use as medicaments

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Thiazole sulfides and their use as immunomodulators

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Fluorine-substituted cyclic amino compounds and methods for their preparation, pharmaceutical compositions and their use

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Decahydroquinoline derivatives, method for their preparation and intermediates thereof, their use as medicaments and their pharmaceutical compositions

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Amino alcohol derivatives and their activity as renin inhibitors

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NOVEL DERIVATIVES OF IMIDAZOLE, PROCESS FOR THEIR PREPARATION, THE NEW INTERMEDIATES OBTAINED, THEIR USE AS MEDICAMENTS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING SAME.

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Gpcr receptor agonists, pharmaceutical compositions comprising the same, and methods for their use

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N-heterocylic gpcr receptor agonists, pharmaceutical compositions comprising the same, and methods for their use

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Benzimidazoyl glp-1 receptor agonists, pharmaceutical compositions comprising the same, and methods for their use

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Gpcr receptor agonists, pharmaceutical compositions comprising the same, and methods for their use

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Benzimidazoyl glp-1 receptor agonists, pharmaceutical compositions comprising the same, and methods for their use

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Bicyclic derivatives, methods for their preparing, pharmaceutical composition containing thereof, their using in treatment and method for treatment of mammals by their using

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Solid forms of the tartrate salt of 3-((1r,3r)-1-(2,6-difluoro-4-((1-(3-fluoropropyl)azetidin-3-yl)amino)phenyl)-3-methyl-1,3,4,9-tetrahydro-2h-pyrido[3,4-b]indol-2-yl)-2,2-difluoropropan-1-ol, process for their preparation and methods of their use in treating cancers

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P- (4-CHLOROBENZOYL) -PHENOXYISOBUTYRIC ACID ESTER OF 3-HYDROXY-QUINUCLIDINE AND ITS DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING SAME, PARTICULARLY USEFUL AS HYPOCHOLESTEROLEMIANTS AND HYPOTRIGLYCERIDEMIANS

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Alkoxybenzylpyridopyrimidines, methods for their preparation, formulations thereof and their use in medicine

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2,2'-Alkylenediindole derivatives, process for their production, medicines containing them and their use as anti-ulcer agents

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Acrylic derivatives of piperazine, the method of preparing same and their application in therapeutics

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Glucocorticoid mimetics, methods for their preparation, pharmaceutical compositions and their application

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New use and new derivatives of imidazole their preparation the new intermediates obtained their use as medicaments and the pharmaceutical compositions containing them

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Naphtacene derivative, process of preparation and compositions containing it

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(n-alkylcarbamoyl) methyl enulosides and related pyranoside containing an alfa, beta, gama, delta - unsaturated ester, their preparation and their efficacy as antibacterial agents

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Berberine salts, ursodeoxycholic salts and combinations, methods of preparation and application thereof

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Solid forms of dabigatran etexilate mesylate and processes for their preparation

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Aza-bicycloalkyl ethers and their use as alpha7-nachr agonists

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5-aminotetrahydroquinoline-2-carboxylic acids and their use

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Aza-bicyloalkyl ethers and their use as alpha7-nachr agonists

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Bicyclic compounds and their use as antibacterial agents and beta-lactamase inhibitors

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Adamantane and azabicyclo-octane and nonane derivatives process of their preparation and their use as dpp-iv inhibitors

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Substituted beta-carbolines, method for their preparing

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Derivatives of benzamide, method for their preparing and pharmaceutical composition based on thereof

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Substituted 1-aminoalkyl-lactams and their use as muscarinic receptor antagonists

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2-amino-8-cyclopropyl-5-oxo-5,8-dihydro-pyrido [2,3-d]- pyrimidine-6-carboxylic acid compounds, their production and their medicinal use

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Substituted thiophenylalkenylcarboxylic acid guanidides, process for their preparation, their use as a medicament or diagnostic, and medicament containing them

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Derivatives of aryl carboxylic acids, methods for their preparing, pharmaceutical composition based on thereof, methods for treatment and prophylaxis of different diseases, intermediate compounds and methods for their preparing

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Diazine-fused amidine compounds as bace inhibitors, compositions, and their use

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Benzoylguanidines substituted by heterocyclic N-oxide, process for their preparation and pharmaceutical compositions containing them

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Indolyl derivatives substituted with a thiazole ring and their use as ppar modulators

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Anthranilamides and methods of their use

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Five-membered heterocycles having biphenylsulfonyl substitution, process for their preparation, their use as a medicament or diagnostic, and medicament comprising them

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Fused heterocyclic isoxazoline derivatives and their use as anti-derpressants

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Anthranilamides with a heteroarylsulfonyl side chain, process for their preparation, their use as medicament or diagnostic aid, and pharmaceutical preparations containing them

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Novel vitronectin receptor antagonist derivatives, method for preparing same, use thereof as medicines and pharmaceutical compositions containing same

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Pyrazolo-quinazoline derivatives, process for their preparation and their use as kinase inhibitors

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N-alkylated thiazolium salts and process for their preparation

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Rhodanine derivatives, a process for their preparation, pharmaceutical compositions and their use

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Benzimidazole derivatives,their preparation process,the intermediates obtained,their use as medicaments and the pharmaceutical compositions containing them

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Sulfonamidodioxepanes, method of their preparation, intermediates, salts and their using

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6-butyl-2,4-dinitrophenols and their esters for use as - soil nematocides or fungicides

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Epoxy modified polyamines and their dithiocarbamic salts useful as water clarifiers

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Epoxy modified polyamines and their dithiocarbamic salts useful as water clarifiers

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New pyrazolylethyl-diethylenetriaminotetraacetic acids and their lanthanide complexes, useful as contrast agents for diagnostic magnetic resonance imaging

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PROCEDURE FOR THE PREPARATION OF NAFTIRIDIN CARBOXYLIC ACIDS AND THEIR SALTS.

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Fluorinated cycloalkyl-substituted benzoylguanidines, method for their preparing, their using as medicinal agent and medicinal agent comprising thereof

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Substituted 5-hydroxy-2-heteroaryl-3-phenylpentanonitrile derivatives, processes for their preparation and their use as herbicides and/or plant growth regulators

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Water soluble fluorescent or colored dyes and methods for their use

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Olivine-type compounds: method for their preparation and use in cathode materials for sodium-ion batteries

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Polymeric ethylene oxide/propylene oxide or ethylene oxide/butylene oxide ether carboxylic acids, a process for their preparation and their use

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Procedure for obtaining acid, 3, 4, 5 trimetoxibenzoilamidocarboxilico and their salts. (Machine-translation by Google Translate, not legally binding)

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PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS

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