COMPOUNDS DERIVED FROM BICYCLE HETEROCICLES; PHARMACEUTICAL COMPOSITION; PREPARATION PROCEDURE; AND USE TO TREAT BENIGN OR MALIGNUM TUMORS, DISEASES OF THE RESPIRATORY ROADS, GASTROINTESTINAL TRACT, BILIARY DUCTS, VESICULA
Номер патента: CL2004000284A1
Опубликовано: 14-01-2005
Автор(ы): Frank Solca Flavio Himmelsbach
Принадлежит: Boehringer Ingelheim Int
Опубликовано: 14-01-2005
Автор(ы): Frank Solca Flavio Himmelsbach
Принадлежит: Boehringer Ingelheim Int
Реферат: LA PRESENTE INVENCIO SE REFIERE A HETEROCICLOS BICICLICOS DE FORMULA GENERAL EN LA QUE Ra,Rb,Rc,Rd,Re Y X SE DEFINEN COMO EN LA REIVINDICACION 1, SUS TAUTOMEROS SUS ESTEROISOMEROS, SU MEZCLAS Y SUS SALES, EN PARTICULAR SUS SALES FISIOLOGICAMENTE COMPATIBLES CON ACIDCOS INORGANICOS U ORGANICOS, LOS CUALES POSEEN VALIOSAS PROPIEDADES FARMACOLOGICAS, EN PARTICULAR UN EFECTO INHIBIDOR SOBRE LA TRANSDUCCION DE SENAL PROPORCIONADA POR LA TIROSINAQUINASAS, SU USO PARA EL TRTAMIENTO DE ENFERMEDADES, EN PARTICULAR DE ENFERMEDADES TUMORALES, ASI COMO DE LA HIPERPLASIA BENIGNA DE LA PROSTATA (BHP) DE ENFERMEDADES DE LOS PULMONES Y DE LAS VIAS RESIRATORIAS Y SU PREPARACION. THE PRESENT INVENTION REFERS TO BICYCLIC HETEROCICLES OF GENERAL FORMULA IN WHICH Ra, Rb, Rc, Rd, Re YX ARE DEFINED AS IN REIVINDICATION 1, ITS TAUTOMERS ITS STEROISOMERS, ITS MIXTURES AND ITS SALTS, IN PARTICULATE ITS PHYSIOLOGICALLY SALTS INORGANIC OR ORGANIC ACIDES, WHICH HAVE VALUABLE PHARMACOLOGICAL PROPERTIES, IN PARTICULATE AN INHIBITING EFFECT ON THE SENAL TRANSDUCTION PROVIDED BY THE THYROSINAQUINAS, ITS USE FOR THE TREATMENT OF DISEASES, IN PARTICULAR AS A DISEASE OF THE DISEASE (BHP) OF DISEASES OF THE LUNGS AND THE RESIRATORY ROADS AND ITS PREPARATION.
Bicyclic heterocycles, pharmaceutical compositions containing these compounds, their use and processes for preparing them
Номер патента: US20100267718A1. Автор: Frank Himmelsbach,Rainer Soyka,Birgit Jung. Владелец: Individual. Дата публикации: 2010-10-21.