30-05-2023 дата публикации
Номер: CN116178236A
Автор:
JIANG YUXIN,
ZHU HONGLIANG,
ZENG WEI,
DING KE,
LIU YUNHAI,
SONG YANFANG,
YANG YANG,
GAO HANG,
CHEN YONG,
ZHAO XIN,
WEI ZHITAO,
LI LEI,
SHI YISHENG,
ZHANG JUE,
LI FENGCHUANG
Принадлежит:
The invention provides a preparation method of N-methyl pyrrolidone. The method takes anhydrous monomethylamine and gamma-butyrolactone as raw materials, and comprises the following steps: S1, mixing anhydrous monomethylamine, gamma-butyrolactone and a liquid phase from a solid-liquid separation step, and reacting to obtain an amination reaction solution containing 4-hydroxy-N-methylbutyramide; s2, cooling the amination reaction liquid to obtain a solid-liquid mixture; s3, carrying out solid-liquid separation on the solid-liquid mixture, returning a liquid phase to S1, mixing the liquid phase with anhydrous monomethylamine and gamma-butyrolactone, and continuing amination reaction; and S4, melting the solid, and then feeding the molten solid into a dehydration reactor to prepare the N-methyl pyrrolidone. The purity gt can be obtained; 99.85 wt% of 4-hydroxy-N-methyl butyramide, and 99.85 wt% of 4-hydroxy The N-methyl pyrrolidone is prepared, and the conversion rate can reach gt; the purity ...
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